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Priya Jaishankar, MS

Title(s)Specialist, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Address600 16th St
San Francisco CA 94158
Phone415-514-1367
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine. ACS Chem Biol. 2020 Apr 17. Bashore C, Jaishankar P, Skelton NJ, Fuhrmann J, Hearn BR, Liu PS, Renslo AR, Dueber EC. PMID: 32302100.
      View in: PubMed   Mentions:    Fields:    
    2. Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J Med Chem. 2019 09 26; 62(18):8480-8496. Pemberton OA, Jaishankar P, Akhtar A, Adams JL, Shaw LN, Renslo AR, Chen Y. PMID: 31483651.
      View in: PubMed   Mentions: 2     Fields:    
    3. Zebrafish studies identify serotonin receptors mediating antiepileptic activity in Dravet syndrome. Brain Commun. 2019; 1(1):fcz008. Griffin AL, Jaishankar P, Grandjean JM, Olson SH, Renslo AR, Baraban SC. PMID: 31667472.
      View in: PubMed   Mentions:
    4. Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound. Cell Chem Biol. 2019 09 19; 26(9):1295-1305.e6. Ehrnhoefer DE, Skotte NH, Reinshagen J, Qiu X, Windshügel B, Jaishankar P, Ladha S, Petina O, Khankischpur M, Nguyen YTN, Caron NS, Razeto A, Meyer Zu Rheda M, Deng Y, Huynh KT, Wittig I, Gribbon P, Renslo AR, Geffken D, Gul S, Hayden MR. PMID: 31353319.
      View in: PubMed   Mentions: 1     Fields:    
    5. Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. ACS Infect Dis. 2019 06 14; 5(6):1013-1021. Torelli NJ, Akhtar A, DeFrees K, Jaishankar P, Pemberton OA, Zhang X, Johnson C, Renslo AR, Chen Y. PMID: 30942078.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    6. Cilia-Associated Oxysterols Activate Smoothened. Mol Cell. 2018 10 18; 72(2):316-327.e5. Raleigh DR, Sever N, Choksi PK, Sigg MA, Hines KM, Thompson BM, Elnatan D, Jaishankar P, Bisignano P, Garcia-Gonzalo FR, Krup AL, Eberl M, Byrne EFX, Siebold C, Wong SY, Renslo AR, Grabe M, McDonald JG, Xu L, Beachy PA, Reiter JF. PMID: 30340023.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Antibacterial Spectrum of a Tetrazole-Based Reversible Inhibitor of Serine ß-Lactamases. Antimicrob Agents Chemother. 2018 08; 62(8). Pemberton OA, Zhang X, Nichols DA, DeFrees K, Jaishankar P, Bonnet R, Adams J, Shaw LN, Renslo AR, Chen Y. PMID: 29844038.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    8. Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Science. 2018 03 30; 359(6383). Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P. PMID: 29599213.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    9. USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature. 2017 10 26; 550(7677):534-538. Kategaya L, Di Lello P, Rougé L, Pastor R, Clark KR, Drummond J, Kleinheinz T, Lin E, Upton JP, Prakash S, Heideker J, McCleland M, Ritorto MS, Alessi DR, Trost M, Bainbridge TW, Kwok MCM, Ma TP, Stiffler Z, Brasher B, Tang Y, Jaishankar P, Hearn BR, Renslo AR, Arkin MR, Cohen F, Yu K, Peale F, Gnad F, Chang MT, Klijn C, Blackwood E, Martin SE, Forrest WF, Ernst JA, Ndubaku C, Wang X, Beresini MH, Tsui V, Schwerdtfeger C, Blake RA, Murray J, Maurer T, Wertz IE. PMID: 29045385.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    10. Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases. J Am Chem Soc. 2017 08 30; 139(34):11650-11653. Acker TM, Gable JE, Bohn MF, Jaishankar P, Thompson MC, Fraser JS, Renslo AR, Craik CS. PMID: 28759216.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6a branch. Elife. 2016 07 20; 5. Gallagher CM, Garri C, Cain EL, Ang KK, Wilson CG, Chen S, Hearn BR, Jaishankar P, Aranda-Diaz A, Arkin MR, Renslo AR, Walter P. PMID: 27435960.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    12. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19; 11(8):870-80. Hearn BR, Jaishankar P, Sidrauski C, Tsai JC, Vedantham P, Fontaine SD, Walter P, Renslo AR. PMID: 26789650.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    13. Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography. J Am Chem Soc. 2015 Jul 01; 137(25):8086-95. Nichols DA, Hargis JC, Sanishvili R, Jaishankar P, Defrees K, Smith EW, Wang KK, Prati F, Renslo AR, Woodcock HL, Chen Y. PMID: 26057252.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    14. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 2015 Apr 15; 4:e07314. Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. PMID: 25875391.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    15. Broad-spectrum allosteric inhibition of herpesvirus proteases. Biochemistry. 2014 Jul 22; 53(28):4648-60. Gable JE, Lee GM, Jaishankar P, Hearn BR, Waddling CA, Renslo AR, Craik CS. PMID: 24977643.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    16. Tailoring small molecules for an allosteric site on procaspase-6. ChemMedChem. 2014 Jan; 9(1):73-7, 2. Murray J, Giannetti AM, Steffek M, Gibbons P, Hearn BR, Cohen F, Tam C, Pozniak C, Bravo B, Lewcock J, Jaishankar P, Ly CQ, Zhao X, Tang Y, Chugha P, Arkin MR, Flygare J, Renslo AR. PMID: 24259468.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    17. Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6. PLoS One. 2012; 7(12):e50864. Heise CE, Murray J, Augustyn KE, Bravo B, Chugha P, Cohen F, Giannetti AM, Gibbons P, Hannoush RN, Hearn BR, Jaishankar P, Ly CQ, Shah K, Stanger K, Steffek M, Tang Y, Zhao X, Lewcock JW, Renslo AR, Flygare J, Arkin MR. PMID: 23227217.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    18. Structure-based design of potent and ligand-efficient inhibitors of CTX-M class A ß-lactamase. J Med Chem. 2012 Mar 08; 55(5):2163-72. Nichols DA, Jaishankar P, Larson W, Smith E, Liu G, Beyrouthy R, Bonnet R, Renslo AR, Chen Y. PMID: 22296601.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    19. Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases. Bioorg Med Chem Lett. 2009 Nov 01; 19(21):6218-21. Bryant C, Kerr ID, Debnath M, Ang KK, Ratnam J, Ferreira RS, Jaishankar P, Zhao D, Arkin MR, McKerrow JH, Brinen LS, Renslo AR. PMID: 19773167.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    20. Potency and selectivity of P2/P3-modified inhibitors of cysteine proteases from trypanosomes. Bioorg Med Chem Lett. 2008 Jan 15; 18(2):624-8. Jaishankar P, Hansell E, Zhao DM, Doyle PS, McKerrow JH, Renslo AR. PMID: 18055204.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    21. A distal methyl substituent attenuates mitochondrial protein synthesis inhibition in oxazolidinone antibacterials. Bioorg Med Chem Lett. 2007 Sep 15; 17(18):5036-40. Renslo AR, Atuegbu A, Herradura P, Jaishankar P, Ji M, Leach KL, Huband MD, Dermyer MR, Wu L, Vara Prasad JV, Gordeev MF. PMID: 17681758.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    22. Conformational constraint in oxazolidinone antibacterials. Part 2: Synthesis and structure-activity studies of oxa-, aza-, and thiabicyclo[3.1.0]hexylphenyl oxazolidinones. Bioorg Med Chem Lett. 2006 Mar 01; 16(5):1126-9. Renslo AR, Gao H, Jaishankar P, Venkatachalam R, Gómez M, Blais J, Huband M, Vara Prasad JV, Gordeev MF. PMID: 16387498.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    23. Conformational constraint in oxazolidinone antibacterials. Synthesis and structure-activity studies of (azabicyclo[3.1.0]hexylphenyl)oxazolidinones. J Med Chem. 2005 Jul 28; 48(15):5009-24. Renslo AR, Jaishankar P, Venkatachalam R, Hackbarth C, Lopez S, Patel DV, Gordeev MF. PMID: 16033280.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    24. Synthesis of aza-, oxa-, and thiabicyclo[3.1.0]hexane heterocycles from a common synthetic intermediate. Org Lett. 2005 Jun 23; 7(13):2627-30. Renslo AR, Gao H, Jaishankar P, Venkatachalam R, Gordeev MF. PMID: 15957907.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
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