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Paul Wolters, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address505 Parnassus Avenue
San Francisco CA 94117
Phone415-514-2601
ORCID ORCID Icon0000-0002-3108-6164 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoClinical Fellowship

    Collapse Overview 
    Collapse Overview
    Dr. Wolters received in his M.D. degree from the University of Minnesota; trained in internal medicine at the University of Colorado, and pulmonary and critical care medicine at the University of California, San Francisco where he joined the division of pulmonary and critical care medicine in 1999. His primary clinical interest is caring for patients with interstitial lung diseases.

    Research Interests
    The goal of my research program is to understand the molecular pathogenesis of fibrotic lung disease and to use this knowledge to develop novel therapies for treating these diseases. My research group investigates lung fibrosis by applying animal models and translational studies using patient samples to define the cellular and molecular mechanisms that promote lung fibrosis. To achieve this goal, we have established a large repository of biological specimens, obtained from generous patients with interstitial lung diseases, and methods for isolating pure populations of alveolar type II cells from fibrotic lungs that can be used to investigate mechanisms of disease pathogenesis. Our recent scientific focus has been on explaining the role epithelial cells play in promoting lung fibrosis with an emphasis on the roles of the unfolded protein response and aging.



    Collapse Research 
    Collapse Research Activities and Funding
    Lung fibrosis mediated by telomere dysfunction in alveolar type II cells
    NIH/NHLBI R01HL139897Jul 5, 2018 - Jun 30, 2022
    Role: Principal Investigator
    Targeting epithelial cells to treat pulmonary fibrosis
    NIH/NHLBI P01HL108794Aug 9, 2012 - Jul 31, 2017
    Role: Co-Investigator
    Analysis of Alveolar Type II cells in Normal and Fibrotic Human Lung
    NIH/NHLBI R21HL104422Apr 1, 2011 - Mar 31, 2013
    Role: Principal Investigator
    Mast Cells and the Host Response in the Lung
    NIH/NHLBI R01HL075026Jul 2, 2004 - Jun 30, 2009
    Role: Principal Investigator
    MAST CELL CYSTEINE PROTEASES IN LUNG INFLAMMATION
    NIH/NHLBI K08HL004055Aug 4, 1999 - Jun 30, 2004
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Telomere length in patients with unclassifiable interstitial lung disease: a cohort study. Eur Respir J. 2020 Aug; 56(2). Ley B, Liu S, Elicker BM, Henry TS, Vittinghoff E, Golden JA, Jones KD, Wolters PJ. PMID: 32341108.
      View in: PubMed   Mentions:    Fields:    
    2. The Pulmonary Fibrosis Foundation Patient Registry: Rationale, Design, and Methods. Ann Am Thorac Soc. 2020 Aug 10. Wang BR, Edwards R, Freiheit EA, Ma Y, Burg C, de Andrade J, Lancaster L, Lindell K, Nathan SD, Raghu G, Gibson K, Gulati M, Mason W, Noth I, Schmidt B, Spino C, Staszak S, Stauffer J, Wolters PJ, Cosgrove GP, Flaherty KR. PMID: 32776789.
      View in: PubMed   Mentions:    Fields:    
    3. Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures. Am J Respir Crit Care Med. 2020 Jun 30. Furusawa H, Cardwell JH, Okamoto T, Walts AD, Konigsberg IR, Kurche JS, Bang TJ, Schwarz MI, Brown KK, Kropski JA, Rojas M, Cool CD, Lee JS, Wolters PJ, Yang IV, Schwartz DA. PMID: 32602730.
      View in: PubMed   Mentions:    Fields:    
    4. Airway Epithelial Telomere Dysfunction Drives Remodeling Similar to Chronic Lung Allograft Dysfunction. Am J Respir Cell Mol Biol. 2020 Jun 18. Naikawadi RP, Green G, Jones KD, Achtar-Zadeh N, Mieleszko JE, Arnould I, Kukreja J, Greenland J, Wolters PJ. PMID: 32551854.
      View in: PubMed   Mentions:    Fields:    
    5. Age-dependent regulation of cell-mediated collagen turnover. JCI Insight. 2020 May 21; 5(10). Podolsky MJ, Yang CD, Valenzuela CL, Datta R, Huang SK, Nishimura SL, Dallas SL, Wolters PJ, Le Saux CJ, Atabai K. PMID: 32315288.
      View in: PubMed   Mentions: 1     Fields:    
    6. A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis. Elife. 2020 May 12; 9. Zhang K, Yao E, Lin C, Chou YT, Wong J, Li J, Wolters PJ, Chuang PT. PMID: 32394892.
      View in: PubMed   Mentions: 1     Fields:    
    7. Long-term ozone exposure is positively associated with telomere length in critically ill patients. Environ Int. 2020 Aug; 141:105780. Wang C, Wolters PJ, Calfee CS, Liu S, Balmes JR, Zhao Z, Koyama T, Ware LB. PMID: 32417614.
      View in: PubMed   Mentions:    Fields:    
    8. Frailty after lung transplantation is associated with impaired health-related quality of life and mortality. Thorax. 2020 08; 75(8):669-678. Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD, Singer JP. PMID: 32376733.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Diaphragmatic Atrophy May Limit Progression of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2020 05 01; 201(9):e72-e73. Venado A, Witt LJ, Kallianos K, Wolters PJ. PMID: 31825660.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nat Commun. 2020 04 21; 11(1):1920. Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, Adams TS, Schupp JC, Poli SD, Rosas IO, Kaminski N, Matthay MA, Wolters PJ, Sheppard D. PMID: 32317643.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Reversal of TGFß1-Driven Profibrotic State in Patients with Pulmonary Fibrosis. N Engl J Med. 2020 03 12; 382(11):1068-1070. Chapman HA, Wei Y, Montas G, Leong D, Golden JA, Trinh BN, Wolters PJ, Le Saux CJ, Jones KD, Hills NK, Foster E, Oldham JM, Linderholm AL, Kotak P, Decaris M, Turner S, Song JW. PMID: 32160670.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. A Systematically Derived Exposure Assessment Instrument for Chronic Hypersensitivity Pneumonitis. Chest. 2020 Jun; 157(6):1506-1512. Barnes H, Morisset J, Molyneaux P, Westall G, Glaspole I, Collard HR. PMID: 31958445.
      View in: PubMed   Mentions:    Fields:    
    13. Peripheral blood leukocyte telomere length is associated with survival of sepsis patients. Eur Respir J. 2020 01; 55(1). Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ. PMID: 31619475.
      View in: PubMed   Mentions: 2     Fields:    
    14. Interaction Between Epithelial and Mesenchymal Cells in Interstitial Lung Disease. . 2020 Jan 1. Max L. Cohen, Paul J. Wolters. .
      View in: Publisher Site   Mentions:
    15. Rare Protein-Altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis. Am J Respir Crit Care Med. 2019 11 01; 200(9):1154-1163. Ley B, Torgerson DG, Oldham JM, Adegunsoye A, Liu S, Li J, Elicker BM, Henry TS, Golden JA, Jones KD, Dressen A, Yaspan BL, Arron JR, Noth I, Hoffmann TJ, Wolters PJ. PMID: 31268371.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. Regulatory T cells in skin are uniquely poised to suppress profibrotic immune responses. Sci Immunol. 2019 09 06; 4(39). Kalekar LA, Cohen JN, Prevel N, Sandoval PM, Mathur AN, Moreau JM, Lowe MM, Nosbaum A, Wolters PJ, Haemel A, Boin F, Rosenblum MD. PMID: 31492709.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    17. Oxygen in patients with fibrotic interstitial lung disease: an international Delphi survey. Eur Respir J. 2019 08; 54(2). Lim RK, Humphreys C, Morisset J, Holland AE, Johannson KA. PMID: 31097522.
      View in: PubMed   Mentions: 3     Fields:    
    18. A nonlinear relationship between visceral adipose tissue and frailty in adult lung transplant candidates. Am J Transplant. 2019 11; 19(11):3155-3161. Anderson MR, Kolaitis NA, Gao Y, Kukreja J, Greenland J, Hays S, Wolters P, Golden J, Diamond J, Palmer S, Arcasoy S, Udupa J, Christie JD, Lederer DJ, Singer JP. PMID: 31278829.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 07 15; 200(2):199-208. Moore C, Blumhagen RZ, Yang IV, Walts A, Powers J, Walker T, Bishop M, Russell P, Vestal B, Cardwell J, Markin CR, Mathai SK, Schwarz MI, Steele MP, Lee J, Brown KK, Loyd JE, Crapo JD, Silverman EK, Cho MH, James JA, Guthridge JM, Cogan JD, Kropski JA, Swigris JJ, Bair C, Kim DS, Ji W, Kim H, Song JW, Maier LA, Pacheco KA, Hirani N, Poon AS, Li F, Jenkins RG, Braybrooke R, Saini G, Maher TM, Molyneaux PL, Saunders P, Zhang Y, Gibson KF, Kass DJ, Rojas M, Sembrat J, Wolters PJ, Collard HR, Sundy JS, O'Riordan T, Strek ME, Noth I, Ma SF, Porteous MK, Kreider ME, Patel NB, Inoue Y, Hirose M, Arai T, Akagawa S, Eickelberg O, Fernandez IE, Behr J, Mogulkoc N, Corte TJ, Glaspole I, Tomassetti S, Ravaglia C, Poletti V, Crestani B, Borie R, Kannengiesser C, Parfrey H, Fiddler C, Rassl D, Molina-Molina M, Machahua C, Worboys AM, Gudmundsson G, Isaksson HJ, Lederer DJ, Podolanczuk AJ, Montesi SB, Bendstrup E, Danchel V, Selman M, Pardo A, Henry MT, Keane MP, Doran P, Vašáková M, Sterclova M, Ryerson CJ, Wilcox PG, Okamoto T, Furusawa H, Miyazaki Y, Laurent G, Baltic S, Prele C, Moodley Y, Shea BS, Ohta K, Suzukawa M, Narumoto O, Nathan SD, Venuto DC, Woldehanna ML, Kokturk N, de Andrade JA, Luckhardt T, Kulkarni T, Bonella F, Donnelly SC, McElroy A, Armstong ME, Aranda A, Carbone RG, Puppo F, Beckman KB, Nickerson DA, Fingerlin TE, Schwartz DA. PMID: 31034279.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    20. Prevalence and Clinical Significance of Antineutrophil Cytoplasmic Antibodies in North American Patients With Idiopathic Pulmonary Fibrosis. Chest. 2019 10; 156(4):715-723. Liu GY, Ventura IB, Achtar-Zadeh N, Elicker BM, Jones KD, Wolters PJ, Collard HR, Adegunsoye A, Strek ME, Ley B. PMID: 31181198.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Pulmonary physiology is poorly associated with radiological extent of disease in systemic sclerosis-associated interstitial lung disease. Eur Respir J. 2019 05; 53(5). Jhajj A, Gill HP, Hague CJ, Murphy D, Elicker B, Soon J, Sulaiman N, Castillo-Saldana D, Wilcox PG, Dunne J, Lee JS, Wolters PJ, Ley B, Jones KD, Morisset J, Ryerson CJ. PMID: 30846470.
      View in: PubMed   Mentions:    Fields:    
    22. Significance of bronchiolocentric fibrosis in patients with histopathological usual interstitial pneumonia. Histopathology. 2019 Jun; 74(7):1088-1097. Tanizawa K, Ley B, Vittinghoff E, Elicker BM, Henry TS, Wolters PJ, Brownell R, Liu S, Collard HR, Jones KD. PMID: 30742318.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    23. Telomere length and genetic variant associations with interstitial lung disease progression and survival. Eur Respir J. 2019 04; 53(4). Newton CA, Oldham JM, Ley B, Anand V, Adegunsoye A, Liu G, Batra K, Torrealba J, Kozlitina J, Glazer C, Strek ME, Wolters PJ, Noth I, Garcia CK. PMID: 30635297.
      View in: PubMed   Mentions: 3     Fields:    
    24. Molecular endpoints for establishing target engagement by novel idiopathic pulmonary fibrosis therapies. Eur Respir J. 2019 03; 53(3). Wolters PJ, Cottin V. PMID: 30886027.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Association between greenhouse working exposure and bronchial asthma: A pilot, cross-sectional survey of 5,420 greenhouse farmers from northeast China. J Occup Environ Hyg. 2019 Apr; 16(4):286-293. Liu S, Wolters PJ, Zhang Y, Zhao M, Liu D, Wang L, Zhao G, Mao S, Wu L, Zhao H, Wang X. PMID: 30822226.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    26. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol. 2019 02; 20(2):163-172. Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi RP, Wolters PJ, Abate AR, Butte AJ, Bhattacharya M. PMID: 30643263.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    27. Increased Extracellular Vesicles Mediate WNT5A Signaling in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2018 12 15; 198(12):1527-1538. Martin-Medina A, Lehmann M, Burgy O, Hermann S, Baarsma HA, Wagner DE, De Santis MM, Ciolek F, Hofer TP, Frankenberger M, Aichler M, Lindner M, Gesierich W, Guenther A, Walch A, Coughlan C, Wolters P, Lee JS, Behr J, Königshoff M. PMID: 30044642.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    28. Pirfenidone in the kaleidoscope: reflecting mechanisms through different angles. Eur Respir J. 2018 11; 52(5). Tzouvelekis A, Wolters PJ. PMID: 30467176.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. Histopathological and molecular analysis of idiopathic pulmonary fibrosis lungs from patients treated with pirfenidone or nintedanib. Histopathology. 2019 Jan; 74(2):341-349. Zhang Y, Jones KD, Achtar-Zadeh N, Green G, Kukreja J, Xu B, Wolters PJ. PMID: 30152895.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    30. MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease. N Engl J Med. 2018 12 06; 379(23):2209-2219. Juge PA, Lee JS, Ebstein E, Furukawa H, Dobrinskikh E, Gazal S, Kannengiesser C, Ottaviani S, Oka S, Tohma S, Tsuchiya N, Rojas-Serrano J, González-Pérez MI, Mejía M, Buendía-Roldán I, Falfán-Valencia R, Ambrocio-Ortiz E, Manali E, Papiris SA, Karageorgas T, Boumpas D, Antoniou K, van Moorsel CHM, van der Vis J, de Man YA, Grutters JC, Wang Y, Borie R, Wemeau-Stervinou L, Wallaert B, Flipo RM, Nunes H, Valeyre D, Saidenberg-Kermanac'h N, Boissier MC, Marchand-Adam S, Frazier A, Richette P, Allanore Y, Sibilia J, Dromer C, Richez C, Schaeverbeke T, Lioté H, Thabut G, Nathan N, Amselem S, Soubrier M, Cottin V, Clément A, Deane K, Walts AD, Fingerlin T, Fischer A, Ryu JH, Matteson EL, Niewold TB, Assayag D, Gross A, Wolters P, Schwarz MI, Holers M, Solomon JJ, Doyle T, Rosas IO, Blauwendraat C, Nalls MA, Debray MP, Boileau C, Crestani B, Schwartz DA, Dieudé P. PMID: 30345907.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    31. Response. Chest. 2018 09; 154(3):727-728. Johannson KA, Vittinghoff E, Morisset J, Wolters PJ, Noth EM, Balmes JR, Collard HR. PMID: 30195362.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    32. Laparoscopic anti-reflux surgery for the treatment of idiopathic pulmonary fibrosis (WRAP-IPF): a multicentre, randomised, controlled phase 2 trial. Lancet Respir Med. 2018 09; 6(9):707-714. Raghu G, Pellegrini CA, Yow E, Flaherty KR, Meyer K, Noth I, Scholand MB, Cello J, Ho LA, Pipavath S, Lee JS, Lin J, Maloney J, Martinez FJ, Morrow E, Patti MG, Rogers S, Wolters PJ, Yates R, Anstrom KJ, Collard HR. PMID: 30100404.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    33. Prognostic and predictive biomarkers for patients with idiopathic pulmonary fibrosis treated with pirfenidone: post-hoc assessment of the CAPACITY and ASCEND trials. Lancet Respir Med. 2018 08; 6(8):615-626. Neighbors M, Cabanski CR, Ramalingam TR, Sheng XR, Tew GW, Gu C, Jia G, Peng K, Ray JM, Ley B, Wolters PJ, Collard HR, Arron JR. PMID: 30072107.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    34. Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study. Lancet Respir Med. 2018 08; 6(8):603-614. Dressen A, Abbas AR, Cabanski C, Reeder J, Ramalingam TR, Neighbors M, Bhangale TR, Brauer MJ, Hunkapiller J, Reeder J, Mukhyala K, Cuenco K, Tom J, Cowgill A, Vogel J, Forrest WF, Collard HR, Wolters PJ, Kropski JA, Lancaster LH, Blackwell TS, Arron JR, Yaspan BL. PMID: 29891356.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    35. Air Pollution Exposure Is Associated With Lower Lung Function, but Not Changes in Lung Function, in Patients With Idiopathic Pulmonary Fibrosis. Chest. 2018 07; 154(1):119-125. Johannson KA, Vittinghoff E, Morisset J, Wolters PJ, Noth EM, Balmes JR, Collard HR. PMID: 29355549.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    36. Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic? Lancet Respir Med. 2018 02; 6(2):154-160. Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G, Maher TM, Molina-Molina M, Noble PW, Raghu G, Richeldi L, Schwarz MI, Selman M, Wuyts WA, Schwartz DA. PMID: 29413083.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    37. Identification of Diagnostic Criteria for Chronic Hypersensitivity Pneumonitis: An International Modified Delphi Survey. Am J Respir Crit Care Med. 2018 04 15; 197(8):1036-1044. Morisset J, Johannson KA, Jones KD, Wolters PJ, Collard HR, Walsh SLF, Ley B. PMID: 29172641.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    38. The MUC5B promoter polymorphism and telomere length in patients with chronic hypersensitivity pneumonitis: an observational cohort-control study. Lancet Respir Med. 2017 08; 5(8):639-647. Ley B, Newton CA, Arnould I, Elicker BM, Henry TS, Vittinghoff E, Golden JA, Jones KD, Batra K, Torrealba J, Garcia CK, Wolters PJ. PMID: 28648751.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    39. Mortality Risk Prediction in Scleroderma-Related Interstitial Lung Disease: The SADL Model. Chest. 2017 11; 152(5):999-1007. Morisset J, Vittinghoff E, Elicker BM, Hu X, Le S, Ryu JH, Jones KD, Haemel A, Golden JA, Boin F, Ley B, Wolters PJ, King TE, Collard HR, Lee JS. PMID: 28629914.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    40. A recurring theme in pulmonary fibrosis genetics. Eur Respir J. 2017 05; 49(5). Wolters PJ. PMID: 28495682.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. Short lung transplant donor telomere length is associated with decreased CLAD-free survival. Thorax. 2017 11; 72(11):1052-1054. Faust HE, Golden JA, Rajalingam R, Wang AS, Green G, Hays SR, Kukreja J, Singer JP, Wolters PJ, Greenland JR. PMID: 28446663.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    42. The performance of the GAP model in patients with rheumatoid arthritis associated interstitial lung disease. Respir Med. 2017 06; 127:51-56. Morisset J, Vittinghoff E, Lee BY, Tonelli R, Hu X, Elicker BM, Ryu JH, Jones KD, Cerri S, Manfredi A, Sebastiani M, Gross AJ, Ley B, Wolters PJ, King TE, Kim DS, Collard HR, Lee JS. PMID: 28502419.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease. Cell. 2017 04 20; 169(3):497-509.e13. Van Dyken SJ, Liang HE, Naikawadi RP, Woodruff PG, Wolters PJ, Erle DJ, Locksley RM. PMID: 28431248.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    44. (323) Decreased Donor PBMC and Allograft Telomere Length Are Associated with Shorter CLAD-Free Survival. The Journal of Heart and Lung Transplantation. 2017 Apr 1; 36(4):s129-s130. H.E. Faust, J.A. Golden, R. Rajalingam, A.S. Wang, G. Green, S.R. Hays, J. Kukreja, J.P. Singer, P.J. Wolters, J.R. Greenland. .
      View in: Publisher Site   Mentions:
    45. CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis. Thorax. 2017 09; 72(9):780-787. Jia G, Chandriani S, Abbas AR, DePianto DJ, N'Diaye EN, Yaylaoglu MB, Moore HM, Peng I, DeVoss J, Collard HR, Wolters PJ, Egen JG, Arron JR. PMID: 28250200.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    46. Pathologic Findings and Prognosis in a Large Prospective Cohort of Chronic Hypersensitivity Pneumonitis. Chest. 2017 09; 152(3):502-509. Wang P, Jones KD, Urisman A, Elicker BM, Urbania T, Johannson KA, Assayag D, Lee J, Wolters PJ, Collard HR, Koth LL. PMID: 28223152.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    47. The use of pretest probability increases the value of high-resolution CT in diagnosing usual interstitial pneumonia. Thorax. 2017 May; 72(5):424-429. Brownell R, Moua T, Henry TS, Elicker BM, White D, Vittinghoff E, Jones KD, Urisman A, Aravena C, Johannson KA, Golden JA, King TE, Wolters PJ, Collard HR, Ley B. PMID: 28082530.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    48. Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity. JCI Insight. 2016 Dec 22; 1(21):e89073. Lofgren S, Hinchcliff M, Carns M, Wood T, Aren K, Arroyo E, Cheung P, Kuo A, Valenzuela A, Haemel A, Wolters PJ, Gordon J, Spiera R, Assassi S, Boin F, Chung L, Fiorentino D, Utz PJ, Whitfield ML, Khatri P. PMID: 28018971.
      View in: PubMed   Mentions: 14     Fields:    
    49. Use of Mycophenolate Mofetil or Azathioprine for the Management of Chronic Hypersensitivity Pneumonitis. Chest. 2017 03; 151(3):619-625. Morisset J, Johannson KA, Vittinghoff E, Aravena C, Elicker BM, Jones KD, Fell CD, Manganas H, Dubé BP, Wolters PJ, Collard HR, Ryerson CJ, Ley B. PMID: 27816444.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    50. Donor-Reactive Regulatory T Cell Frequency Increases During Acute Cellular Rejection of Lung Allografts. Transplantation. 2016 10; 100(10):2090-8. Greenland JR, Wong CM, Ahuja R, Wang AS, Uchida C, Golden JA, Hays SR, Leard LE, Rajalingam R, Singer JP, Kukreja J, Wolters PJ, Caughey GH, Tang Q. PMID: 27077597.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    51. Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis. JCI Insight. 2016 09 08; 1(14):e86704. Naikawadi RP, Disayabutr S, Mallavia B, Donne ML, Green G, La JL, Rock JR, Looney MR, Wolters PJ. PMID: 27699234.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    52. Brief Report: Whole-Exome Sequencing for Identification of Potential Causal Variants for Diffuse Cutaneous Systemic Sclerosis. Arthritis Rheumatol. 2016 09; 68(9):2257-62. Mak AC, Tang PL, Cleveland C, Smith MH, Kari Connolly M, Katsumoto TR, Wolters PJ, Kwok PY, Criswell LA. PMID: 27111861.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    53. Amplification of TGFß Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis. PLoS One. 2016; 11(8):e0158047. Tatler AL, Goodwin AT, Gbolahan O, Saini G, Porte J, John AE, Clifford RL, Violette SM, Weinreb PH, Parfrey H, Wolters PJ, Gauldie J, Kolb M, Jenkins G. PMID: 27494713.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    54. miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis. PLoS One. 2016; 11(6):e0158367. Disayabutr S, Kim EK, Cha SI, Green G, Naikawadi RP, Jones KD, Golden JA, Schroeder A, Matthay MA, Kukreja J, Erle DJ, Collard HR, Wolters PJ. PMID: 27362652.
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    55. Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia. BMC Genet. 2016 06 07; 17(1):74. Fingerlin TE, Zhang W, Yang IV, Ainsworth HC, Russell PH, Blumhagen RZ, Schwarz MI, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch DA, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Murphy E, Smith K, McKean D, Pedersen BS, Talbert J, Powers J, Markin CR, Beckman KB, Lathrop M, Freed B, Langefeld CD, Schwartz DA. PMID: 27266705.
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    56. A diagnostic model for chronic hypersensitivity pneumonitis. Thorax. 2016 10; 71(10):951-4. Johannson KA, Elicker BM, Vittinghoff E, Assayag D, de Boer K, Golden JA, Jones KD, King TE, Koth LL, Lee JS, Ley B, Wolters PJ, Collard HR. PMID: 27245779.
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    57. Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin avß6 Expression. J Biol Chem. 2016 Apr 29; 291(18):9540-53. Tatler AL, Habgood A, Porte J, John AE, Stavrou A, Hodge E, Kerama-Likoko C, Violette SM, Weinreb PH, Knox AJ, Laurent G, Parfrey H, Wolters PJ, Wallace W, Alberti S, Nordheim A, Jenkins G. PMID: 26861876.
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    58. Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes. Sci Rep. 2016 Jan 22; 6:19755. Withana NP, Ma X, McGuire HM, Verdoes M, van der Linden WA, Ofori LO, Zhang R, Li H, Sanman LE, Wei K, Yao S, Wu P, Li F, Huang H, Xu Z, Wolters PJ, Rosen GD, Collard HR, Zhu Z, Cheng Z, Bogyo M. PMID: 26797565.
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    59. Frailty Phenotypes, Disability, and Outcomes in Adult Candidates for Lung Transplantation. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1325-34. Singer JP, Diamond JM, Gries CJ, McDonnough J, Blanc PD, Shah R, Dean MY, Hersh B, Wolters PJ, Tokman S, Arcasoy SM, Ramphal K, Greenland JR, Smith N, Heffernan P, Shah L, Shrestha P, Golden JA, Blumenthal NP, Huang D, Sonett J, Hays S, Oyster M, Katz PP, Robbins H, Brown M, Leard LE, Kukreja J, Bacchetta M, Bush E, D'Ovidio F, Rushefski M, Raza K, Christie JD, Lederer DJ. PMID: 26258797.
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    60. Interstitial lung diseases in the hospitalized patient. BMC Med. 2015 Sep 25; 13:245. Disayabutr S, Calfee CS, Collard HR, Wolters PJ. PMID: 26407727.
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    61. Survival in interstitial pneumonia with features of autoimmune disease: a comparison of proposed criteria. Respir Med. 2015 Oct; 109(10):1326-31. Assayag D, Kim EJ, Elicker BM, Jones KD, Golden JA, King TE, Koth LL, Shum AK, Wolters PJ, Collard HR, Lee JS. PMID: 26303338.
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    62. The effect of bronchodilators on forced vital capacity measurement in patients with idiopathic pulmonary fibrosis. Respir Med. 2015 Aug; 109(8):1058-62. Assayag D, Vittinghoff E, Ryerson CJ, Cocconcelli E, Tonelli R, Hu X, Elicker BM, Golden JA, Jones KD, King TE, Koth LL, Lee JS, Ley B, Shum AK, Wolters PJ, Ryu JH, Collard HR. PMID: 26140806.
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    63. Lung transplantation for hypersensitivity pneumonitis. Chest. 2015 Jun; 147(6):1558-1565. Kern RM, Singer JP, Koth L, Mooney J, Golden J, Hays S, Greenland J, Wolters P, Ghio E, Jones KD, Leard L, Kukreja J, Blanc PD. PMID: 25412059.
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    64. Classification of usual interstitial pneumonia in patients with interstitial lung disease: assessment of a machine learning approach using high-dimensional transcriptional data. Lancet Respir Med. 2015 Jun; 3(6):473-82. Kim SY, Diggans J, Pankratz D, Huang J, Pagan M, Sindy N, Tom E, Anderson J, Choi Y, Lynch DA, Steele MP, Flaherty KR, Brown KK, Farah H, Bukstein MJ, Pardo A, Selman M, Wolters PJ, Nathan SD, Colby TV, Myers JL, Katzenstein AL, Raghu G, Kennedy GC. PMID: 26003389.
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    65. Transforming Growth Factor-ß and Interleukin-1ß Signaling Pathways Converge on the Chemokine CCL20 Promoter. J Biol Chem. 2015 Jun 05; 290(23):14717-28. Brand OJ, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson AJ, Hill A, Jablons D, Wolters P, Lou J, Marks JD, Baron JL, Nishimura SL. PMID: 25918170.
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    66. (384) Mild Acute Cellular Rejection Is Associated With Systemic Donor-Specific Regulatory and Conventional T Cell Responses. The Journal of Heart and Lung Transplantation. 2015 Apr 1; 34(4):s148. J.R. Greenland, C.M. Wong, R. Ahuja, C. Uchida, J.A. Golden, S.R. Hays, L.E. Leard, J.P. Singer, J. Kukreja, P.J. Wolters, G.H. Caughey, Q. Tang. .
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    68. Subacute onset of pulmonary langerhans cell histiocytosis with resolution after smoking cessation. Am J Respir Crit Care Med. 2014 Dec 01; 190(11):e64. Wolters PJ, Elicker BM. PMID: 25436789.
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    69. P23 Target And Biomarker Discovery For Hedgehog Pathway Activity In Idiopathic Pulmonary Fibrosis In Support Of A Phase 2 Randomised, Double-blind, Placebo-controlled Study To Assess Efficacy And Safety Of Vismodegib In Ipf (island). Thorax. 2014 Dec 1; 69(Suppl 2):a87-a87. G Jia, S Chandriani, AR Abbas, D DePianto, E N’Diaye, M Yaylaoglu, HR Collard, P Wolters, J Egen, A Scalori, A Ackrill, J Hou, J Kaminski, TM Maher, Arron. .
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    70. Fibulin-1 predicts disease progression in patients with idiopathic pulmonary fibrosis. Chest. 2014 Oct; 146(4):1055-1063. Jaffar J, Unger S, Corte TJ, Keller M, Wolters PJ, Richeldi L, Cerri S, Prêle CM, Hansbro PM, Argraves WS, Oliver RA, Oliver BG, Black JL, Burgess JK. PMID: 24832167.
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    71. Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis. Thorax. 2015 Jan; 70(1):48-56. DePianto DJ, Chandriani S, Abbas AR, Jia G, N'Diaye EN, Caplazi P, Kauder SE, Biswas S, Karnik SK, Ha C, Modrusan Z, Matthay MA, Kukreja J, Collard HR, Egen JG, Wolters PJ, Arron JR. PMID: 25217476.
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    72. Dipeptidyl peptidase I controls survival from Klebsiella pneumoniae lung infection by processing surfactant protein D. Biochem Biophys Res Commun. 2014 Jul 18; 450(1):818-823. Sutherland RE, Barry SS, Olsen JS, Salantes DB, Caughey GH, Wolters PJ. PMID: 24955853.
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    73. Selective targeting of TGF-ß activation to treat fibroinflammatory airway disease. Sci Transl Med. 2014 Jun 18; 6(241):241ra79. Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL. PMID: 24944194.
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    74. Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation. Lancet Respir Med. 2014 Jul; 2(7):557-65. Stuart BD, Lee JS, Kozlitina J, Noth I, Devine MS, Glazer CS, Torres F, Kaza V, Girod CE, Jones KD, Elicker BM, Ma SF, Vij R, Collard HR, Wolters PJ, Garcia CK. PMID: 24948432.
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    75. Accumulation of BDCA1? dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. PLoS One. 2014; 9(6):e99084. Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS. PMID: 24915147.
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    76. Endogenously expressed IL-13Ra2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts. J Immunol. 2014 Jul 01; 193(1):111-9. Chandriani S, DePianto DJ, N'Diaye EN, Abbas AR, Jackman J, Bevers J, Ramirez-Carrozzi V, Pappu R, Kauder SE, Toy K, Ha C, Modrusan Z, Wu LC, Collard HR, Wolters PJ, Egen JG, Arron JR. PMID: 24879793.
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    77. Diagnosis of idiopathic pulmonary fibrosis with high-resolution CT. Lancet Respir Med. 2014 May; 2(5):e5. Johannson KA, de Boer K, Wolters PJ, Golden JA, Lee JS, Collard HR. PMID: 24815808.
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    78. Predicting survival across chronic interstitial lung disease: the ILD-GAP model. Chest. 2014 Apr; 145(4):723-728. Ryerson CJ, Vittinghoff E, Ley B, Lee JS, Mooney JJ, Jones KD, Elicker BM, Wolters PJ, Koth LL, King TE, Collard HR. PMID: 24114524.
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    79. Serum IgE clearance is facilitated by human FceRI internalization. J Clin Invest. 2014 Mar; 124(3):1187-98. Greer AM, Wu N, Putnam AL, Woodruff PG, Wolters P, Kinet JP, Shin JS. PMID: 24569373.
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    80. Increased susceptibility to Klebsiella pneumonia and mortality in GSNOR-deficient mice. Biochem Biophys Res Commun. 2013 Dec 06; 442(1-2):122-6. Tang CH, Seeley EJ, Huang X, Wolters PJ, Liu L. PMID: 24239886.
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    81. BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease. Sci Transl Med. 2013 Oct 09; 5(206):206ra139. Shum AK, Alimohammadi M, Tan CL, Cheng MH, Metzger TC, Law CS, Lwin W, Perheentupa J, Bour-Jordan H, Carel JC, Husebye ES, De Luca F, Janson C, Sargur R, Dubois N, Kajosaari M, Wolters PJ, Chapman HA, Kämpe O, Anderson MS. PMID: 24107778.
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    82. Pathogenesis of idiopathic pulmonary fibrosis. Annu Rev Pathol. 2014; 9:157-79. Wolters PJ, Collard HR, Jones KD. PMID: 24050627.
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    83. Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet. 2013 Jun; 45(6):613-20. Fingerlin TE, Murphy E, Zhang W, Peljto AL, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch D, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Cogan JD, Mason WR, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Smith K, McKean D, Pedersen BS, Talbert J, Kidd RN, Markin CR, Beckman KB, Lathrop M, Schwarz MI, Schwartz DA. PMID: 23583980.
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    84. Noradrenergic neurons regulate monocyte trafficking and mortality during gram-negative peritonitis in mice. J Immunol. 2013 May 01; 190(9):4717-24. Seeley EJ, Barry SS, Narala S, Matthay MA, Wolters PJ. PMID: 23543756.
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    85. Prevalence and prognosis of unclassifiable interstitial lung disease. Eur Respir J. 2013 Sep; 42(3):750-7. Ryerson CJ, Urbania TH, Richeldi L, Mooney JJ, Lee JS, Jones KD, Elicker BM, Koth LL, King TE, Wolters PJ, Collard HR. PMID: 23222877.
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    86. S69 Transcriptional Mechanisms Regulating Expression of the Avb6 Integrin in IPF. Thorax. 2012 Dec 1; 67(Suppl 2):a34. AL Tatler, G Saini, A Goodwin, O Gbolohan, RL Clifford, M Al’Hourani, J Porte, S Violette, P Weinreb, A Knox, G Laurent, P Wolters, J Gauldie, M Kolb, G Jenkins. .
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    88. Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis. Respir Res. 2012 Nov 20; 13:105. Cha SI, Ryerson CJ, Lee JS, Kukreja J, Barry SS, Jones KD, Elicker BM, Kim DS, Papa FR, Collard HR, Wolters PJ. PMID: 23167970.
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    89. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16354-9. Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan YN, Jan LY, Rock JR. PMID: 22988107.
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    91. Inflection points in sepsis biology: from local defense to systemic organ injury. Am J Physiol Lung Cell Mol Physiol. 2012 Sep; 303(5):L355-63. Seeley EJ, Matthay MA, Wolters PJ. PMID: 22707617.
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    92. Noradrenergic neurons regulate the egress and trafficking of splenic monocytes and influence mortality during Gram-negative infection in mice. Critical Care. 2012 Jun 1; 16(Suppl 3):p71. EJ Seeley, S Barry, M Matthay, PJ Wolters. .
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    95. Bronchoalveolar lavage pepsin in acute exacerbation of idiopathic pulmonary fibrosis. Eur Respir J. 2012 Feb; 39(2):352-8. Lee JS, Song JW, Wolters PJ, Elicker BM, King TE, Kim DS, Collard HR. PMID: 22183478.
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    96. Parasitic infection improves survival from septic peritonitis by enhancing mast cell responses to bacteria in mice. PLoS One. 2011; 6(11):e27564. Sutherland RE, Xu X, Kim SS, Seeley EJ, Caughey GH, Wolters PJ. PMID: 22110673.
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    97. Interleukin-1beta induces increased transcriptional activation of the transforming growth factor-beta-activating integrin subunit beta8 through altering chromatin architecture. J Biol Chem. 2011 Oct 21; 286(42):36864-74. Markovics JA, Araya J, Cambier S, Somanath S, Gline S, Jablons D, Hill A, Wolters PJ, Nishimura SL. PMID: 21878622.
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    98. Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2011 Dec 15; 184(12):1390-4. Lee JS, Ryu JH, Elicker BM, Lydell CP, Jones KD, Wolters PJ, King TE, Collard HR. PMID: 21700909.
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    99. In search of the fibrotic epithelial cell: opportunities for a collaborative network. Thorax. 2012 Feb; 67(2):179-82. Jenkins G, Blanchard A, Borok Z, Bradding P, Ehrhardt C, Fisher A, Hirani N, Johnson S, Königshoff M, Maher TM, Millar A, Parfrey H, Scotton C, Tetley T, Thickett D, Wolters P. PMID: 21680569.
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    100. Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice. J Leukoc Biol. 2011 Sep; 90(3):591-7. Seeley EJ, Sutherland RE, Kim SS, Wolters PJ. PMID: 21653231.
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    101. Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin avß8-mediated activation of TGF-ß. J Clin Invest. 2011 Jul; 121(7):2863-75. Kitamura H, Cambier S, Somanath S, Barker T, Minagawa S, Markovics J, Goodsell A, Publicover J, Reichardt L, Jablons D, Wolters P, Hill A, Marks JD, Lou J, Pittet JF, Gauldie J, Baron JL, Nishimura SL. PMID: 21646718.
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    102. Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2011 Jul; 301(1):L71-8. Marmai C, Sutherland RE, Kim KK, Dolganov GM, Fang X, Kim SS, Jiang S, Golden JA, Hoopes CW, Matthay MA, Chapman HA, Wolters PJ. PMID: 21498628.
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    103. Viral infection in acute exacerbation of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2011 Jun 15; 183(12):1698-702. Wootton SC, Kim DS, Kondoh Y, Chen E, Lee JS, Song JW, Huh JW, Taniguchi H, Chiu C, Boushey H, Lancaster LH, Wolters PJ, DeRisi J, Ganem D, Collard HR. PMID: 21471095.
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    106. Undifferentiated connective tissue disease-associated interstitial lung disease: changes in lung function. Lung. 2010 Apr; 188(2):143-9. Kinder BW, Shariat C, Collard HR, Koth LL, Wolters PJ, Golden JA, Panos RJ, King TE. PMID: 20069430.
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    107. Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages. J Clin Invest. 2009 Dec; 119(12):3713-22. Atabai K, Jame S, Azhar N, Kuo A, Lam M, McKleroy W, Dehart G, Rahman S, Xia DD, Melton AC, Wolters P, Emson CL, Turner SM, Werb Z, Sheppard D. PMID: 19884654.
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    108. Could N-acetylcysteine slow progression of idiopathic pulmonary fibrosis by inhibiting EMT? Am J Physiol Lung Cell Mol Physiol. 2009 Nov; 297(5):L803-4. Wolters PJ. PMID: 19700642.
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    109. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med. 2009 Aug; 15(8):940-5. Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP. PMID: 19633655.
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    110. Neutrophil-derived IL-6 limits alveolar barrier disruption in experimental ventilator-induced lung injury. J Immunol. 2009 Jun 15; 182(12):8056-62. Wolters PJ, Wray C, Sutherland RE, Kim SS, Koff J, Mao Y, Frank JA. PMID: 19494331.
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    112. Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killing. J Immunol. 2008 Oct 15; 181(8):5598-605. Sutherland RE, Olsen JS, McKinstry A, Villalta SA, Wolters PJ. PMID: 18832718.
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    113. Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest. 2007 Nov; 117(11):3359-68. Sun J, Sukhova GK, Yang M, Wolters PJ, MacFarlane LA, Libby P, Sun C, Zhang Y, Liu J, Ennis TL, Knispel R, Xiong W, Thompson RW, Baxter BT, Shi GP. PMID: 17932568.
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    115. Use of mycophenolate mofetil to treat scleroderma-associated interstitial lung disease. Respir Med. 2008 Jan; 102(1):150-5. Zamora AC, Wolters PJ, Collard HR, Connolly MK, Elicker BM, Webb WR, King TE, Golden JA. PMID: 17822892.
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    116. Relationships between early inflammatory response to bleomycin and sensitivity to lung fibrosis: a role for dipeptidyl-peptidase I and tissue inhibitor of metalloproteinase-3? Am J Respir Crit Care Med. 2007 Dec 01; 176(11):1098-107. Pottier N, Chupin C, Defamie V, Cardinaud B, Sutherland R, Rios G, Gauthier F, Wolters PJ, Berthiaume Y, Barbry P, Mari B. PMID: 17673693.
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    117. Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease? Am J Respir Crit Care Med. 2007 Oct 01; 176(7):691-7. Kinder BW, Collard HR, Koth L, Daikh DI, Wolters PJ, Elicker B, Jones KD, King TE. PMID: 17556720.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    118. Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nat Med. 2007 Jun; 13(6):719-24. Sun J, Sukhova GK, Wolters PJ, Yang M, Kitamoto S, Libby P, MacFarlane LA, Mallen-St Clair J, Shi GP. PMID: 17546038.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    119. Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis. Gastroenterology. 2007 Jun; 132(7):2422-37. Cottrell GS, Amadesi S, Pikios S, Camerer E, Willardsen JA, Murphy BR, Caughey GH, Wolters PJ, Coughlin SR, Peterson A, Knecht W, Pothoulakis C, Bunnett NW, Grady EF. PMID: 17570216.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    120. Clinical problem-solving. Anchors away. N Engl J Med. 2007 Feb 01; 356(5):504-9. Calfee CS, Shah SJ, Wolters PJ, Saint S, King TE. PMID: 17267911.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    121. Neutrophil histamine contributes to inflammation in mycoplasma pneumonia. J Exp Med. 2006 Dec 25; 203(13):2907-17. Xu X, Zhang D, Zhang H, Wolters PJ, Killeen NP, Sullivan BM, Locksley RM, Lowell CA, Caughey GH. PMID: 17158962.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    122. Cutting edge: Deficiency of macrophage migration inhibitory factor impairs murine airway allergic responses. J Immunol. 2006 Nov 01; 177(9):5779-84. Wang B, Huang X, Wolters PJ, Sun J, Kitamoto S, Yang M, Riese R, Leng L, Chapman HA, Finn PW, David JR, Bucala R, Shi GP. PMID: 17056501.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    123. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci U S A. 2006 Aug 29; 103(35):13180-5. Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. PMID: 16924102.
      View in: PubMed   Mentions: 435     Fields:    Translation:HumansAnimalsCells
    124. Cathepsins L and S are not required for activation of dipeptidyl peptidase I (cathepsin C) in mice. Biol Chem. 2006 Aug; 387(8):1143-6. Mallen-St Clair J, Shi GP, Sutherland RE, Chapman HA, Caughey GH, Wolters PJ. PMID: 16895486.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    125. Neurofibromatosis-associated lung disease: a case series and literature review. Eur Respir J. 2007 Jan; 29(1):210-4. Zamora AC, Collard HR, Wolters PJ, Webb WR, King TE. PMID: 16870664.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    126. Mast cells protect mice from Mycoplasma pneumonia. Am J Respir Crit Care Med. 2006 Jan 15; 173(2):219-25. Xu X, Zhang D, Lyubynska N, Wolters PJ, Killeen NP, Baluk P, McDonald DM, Hawgood S, Caughey GH. PMID: 16210667.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    127. c-Kit immunophenotyping and metalloproteinase expression profiles of mast cells in interstitial lung diseases. J Pathol. 2005 Jul; 206(3):279-90. Edwards ST, Cruz AC, Donnelly S, Dazin PF, Schulman ES, Jones KD, Wolters PJ, Hoopes C, Dolganov GM, Fang KC. PMID: 15887294.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    128. Tissue-selective mast cell reconstitution and differential lung gene expression in mast cell-deficient Kit(W-sh)/Kit(W-sh) sash mice. Clin Exp Allergy. 2005 Jan; 35(1):82-8. Wolters PJ, Mallen-St Clair J, Lewis CC, Villalta SA, Baluk P, Erle DJ, Caughey GH. PMID: 15649271.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    129. Mast cell dipeptidyl peptidase I mediates survival from sepsis. J Clin Invest. 2004 Feb; 113(4):628-34. Mallen-St Clair J, Pham CT, Villalta SA, Caughey GH, Wolters PJ. PMID: 14966572.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    130. High-resolution organellar genome analysis of Triticum and Aegilops sheds new light on cytoplasm evolution in wheat. Theor Appl Genet. 2004 Apr; 108(6):1182-90. Provan J, Wolters P, Caldwell KH, Powell W. PMID: 15067406.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    131. Mast cell cathepsins C and S control levels of carboxypeptidase A and the chymase, mouse mast cell protease 5. Biol Chem. 2003 Oct-Nov; 384(10-11):1527-31. Henningsson F, Wolters P, Chapman HA, Caughey GH, Pejler G. PMID: 14669996.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    132. Structure and activity of human pancreasin, a novel tryptic serine peptidase expressed primarily by the pancreas. J Biol Chem. 2003 Jan 31; 278(5):3363-71. Bhagwandin VJ, Hau LW, Mallen-St Clair J, Wolters PJ, Caughey GH. PMID: 12441343.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    133. Lys40 but not Arg143 influences selectivity of angiotensin conversion by human alpha-chymase. Biochim Biophys Acta. 2002 Apr 29; 1596(2):346-56. Muilenburg DJ, Raymond WW, Wolters PJ, Caughey GH. PMID: 12007614.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    134. Frequencies of Ty1- copia and Ty3- gypsy retroelements within the Triticeae EST databases. Theor Appl Genet. 2002 Apr; 104(5):840-844. Echenique V, Stamova B, Wolters P, Lazo G, Carollo L, Dubcovsky J. PMID: 12582644.
      View in: PubMed   Mentions: 19     Fields:    
    135. Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice. J Biol Chem. 2001 May 25; 276(21):18551-6. Wolters PJ, Pham CT, Muilenburg DJ, Ley TJ, Caughey GH. PMID: 11279033.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    136. Importance of lysosomal cysteine proteases in lung disease. Respir Res. 2000; 1(3):170-7. Wolters PJ, Chapman HA. PMID: 11667982.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    137. Angiotensin II generation by mast cell alpha- and beta-chymases. Biochim Biophys Acta. 2000 Jul 14; 1480(1-2):245-57. Caughey GH, Raymond WW, Wolters PJ. PMID: 10899625.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    138. Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families. J Immunol. 2000 Jun 15; 164(12):6566-75. Caughey GH, Raymond WW, Blount JL, Hau LW, Pallaoro M, Wolters PJ, Verghese GM. PMID: 10843716.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    139. Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways. Am J Respir Cell Mol Biol. 2000 Feb; 22(2):183-90. Wolters PJ, Laig-Webster M, Caughey GH. PMID: 10657939.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    140. Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta. J Immunol. 1999 May 01; 162(9):5528-35. Fang KC, Wolters PJ, Steinhoff M, Bidgol A, Blount JL, Caughey GH. PMID: 10228034.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    141. Regulated expression, processing, and secretion of dog mast cell dipeptidyl peptidase I. J Biol Chem. 1998 Jun 19; 273(25):15514-20. Wolters PJ, Raymond WW, Blount JL, Caughey GH. PMID: 9624139.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    142. Polymer length of teichuronic acid released from cell walls of Micrococcus luteus. J Bacteriol. 1990 Sep; 172(9):5154-9. Wolters PJ, Hildebrandt KM, Dickie JP, Anderson JS. PMID: 2394683.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    143. Evidence for chloride secretion in the intestine of the winter flounder. Am J Physiol. 1990 Feb; 258(2 Pt 1):C243-7. O'Grady SM, Wolters PJ. PMID: 2305867.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    144. Cardiac antisecretory peptide inhibits intestinal chloride secretion. Am J Physiol. 1989 Oct; 257(4 Pt 1):C775-80. O'Grady SM, Wolters PJ. PMID: 2801925.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    145. Sodium and chloride transport across the isolated porcine gallbladder. Am J Physiol. 1989 Jul; 257(1 Pt 1):C45-51. O'Grady SM, Wolters PJ. PMID: 2750890.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    146. Regulation of ion transport in porcine gallbladder: effects of VIP and norepinephrine. Am J Physiol. 1989 Jul; 257(1 Pt 1):C52-7. O'Grady SM, Wolters PJ, Hildebrand K, Brown DR. PMID: 2546435.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
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