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Molecular underpinnings of aging contributing to systemic sclerosis pathogenesis. Current Opinion in Rheumatology. 2024 Oct 18.
Yang YM, Boin BF, Wolters WP. .
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Molecular Endotypes of Idiopathic Pulmonary Fibrosis: A Latent Class Analysis of Two Multicenter Observational Cohorts. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):455-464.
Maddali MV, Moore AR, Sinha P, Newton CA, Kim JS, Adegunsoye A, Ma SF, Strek ME, Chen CH, Linderholm AL, Zemans RL, Moore BB, Wolters PJ, Martinez FJ, Rogers AJ, Raj R, Noth I, Oldham JM. PMID: 38913573; PMCID: PMC11351813.
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2 Fields:
Translation:
Humans
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Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis. Nature. 2024 Jul; 631(8021):627-634.
Tsukui T, Wolters PJ, Sheppard D. PMID: 38987592.
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5 Fields:
Translation:
HumansAnimalsCells
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A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis. J Clin Invest. 2024 Jul 09; 134(18).
Cohen ML, Brumwell AN, Ho TC, Garakani K, Montas G, Leong D, Ding VW, Golden JA, Trinh BN, Jablons DM, Matthay MA, Jones KD, Wolters PJ, Wei Y, Chapman HA, Le Saux CJ. PMID: 38980870; PMCID: PMC11405054.
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Phage Immunoprecipitation-Sequencing Reveals CDHR5 Autoantibodies in Select Patients With Interstitial Lung Disease. ACR Open Rheumatol. 2024 Sep; 6(9):568-580.
Upadhyay V, Yoon YM, Vazquez SE, Velez TE, Jones KD, Lee CT, Law CS, Wolters PJ, Lee S, Yang MM, Farrand E, Noth I, Strek ME, Anderson MS, DeRisi JL, Sperling AI, Shum AK. PMID: 38952015; PMCID: PMC11506559.
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Proteomic profiling of bronchoalveolar lavage fluid uncovers protein clusters linked to survival in idiopathic forms of interstitial lung disease. ERJ Open Research. 2024 Jun 20; 00192-2024.
Ngo NL, Rekowski RM, Koestler KD, Yorozuya YT, Saito SA, Azeem AI, Harrison HA, Demoruelle DM, Boomer BJ, England EB, Wolters WP, Molyneaux MP, Castro CM, Lee LJ, Solomon SJ, Koronuma KK, Washburn WM, Matson MS. .
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PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2024 Sep 01; 327(3):L319-L326.
Kudryashova TV, Zaitsev SV, Jiang L, Buckley BJ, McGuckin JP, Goncharov D, Zhyvylo I, Lin D, Newcomb G, Piper B, Bogamuwa S, Saiyed A, Teos L, Pena A, Ranson M, Greenland JR, Wolters PJ, Kelso MJ, Poncz M, DeLisser HM, Cines DB, Goncharova EA, Farkas L, Stepanova V. PMID: 38860847; PMCID: PMC11444499.
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1 Fields:
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HumansAnimalsCells
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Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry. Lung. 2024 Jun; 202(3):269-273.
Chang SE, Jia G, Gao X, Schiffman C, Gupta S, Wolters P, Neighbors M. PMID: 38753183; PMCID: PMC11142961.
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Humans
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The Next Best Thing. Chest. 2024 May; 165(5):1033-1034.
Pugashetti JV, Wolters PJ. PMID: 38724139.
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An in vivo screening platform identifies senolytic compounds that target p16INK4a+ fibroblasts in lung fibrosis. J Clin Invest. 2024 Mar 07; 134(9).
Lee JY, Reyes NS, Ravishankar S, Zhou M, Krasilnikov M, Ringler C, Pohan G, Wilson C, Ang KK, Wolters PJ, Tsukui T, Sheppard D, Arkin MR, Peng T. PMID: 38451724; PMCID: PMC11060735.
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1 Fields:
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HumansAnimalsCells
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Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover. Nat Commun. 2024 Feb 20; 15(1):1531.
Podolsky MJ, Kheyfets B, Pandey M, Beigh AH, Yang CD, Lizama CO, Datta R, Lin LL, Wang Z, Wolters PJ, McManus MT, Qi L, Atabai K. PMID: 38378719; PMCID: PMC10879544.
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PubMed Mentions:
1 Fields:
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HumansAnimalsCells
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Gene expression meta-analysis reveals aging and cellular senescence signatures in scleroderma-associated interstitial lung disease. Frontiers in Immunology. 2024 Jan 25; 15:1326922.
Yang YM, Lee LS, Neely NJ, Hinchcliff HM, Wolters WP, Sirota SM. .
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Reply: Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease. Eur Respir J. 2024 Jan; 63(1).
Zhang D, Adegunsoye A, Oldham JM, Wolters PJ, Garcia CK, Newton CA. PMID: 38237997; PMCID: PMC11002962.
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HumansCells
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Short peripheral blood leukocyte telomere length in rheumatoid arthritis-interstitial lung disease. Thorax. 2024 01 18; 79(2):182-185.
Doyle TJ, Juge PA, Peljto AL, Lee S, Walts AD, Esposito AJ, Poli S, Gill R, Hatabu H, Nishino M, Dellaripa PF, Weinblatt ME, Shadick NA, Demoruelle MK, Sparks JA, Rosas IO, Granger B, Deane KD, Crestani B, Wolters PJ, Dieudé P, Lee JS. PMID: 38071573; PMCID: PMC10911453.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Invasive mucinous adenocarcinoma of the lung with bronchorrhea - A marked reduction volume of sputum after SARS-CoV-2 infection. Respir Med Case Rep. 2024; 47:101982.
Liu X, Zhou X, Zhang X, Sun L, Zhao G, Mao S, Li F, Gu X, Wolters PJ, Liu S. PMID: 38298453; PMCID: PMC10828440.
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Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease. Eur Respir J. 2023 11; 62(5).
Zhang D, Adegunsoye A, Oldham JM, Kozlitina J, Garcia N, Poonawalla M, Strykowski R, Linderholm AL, Ley B, Ma SF, Noth I, Strek ME, Wolters PJ, Garcia CK, Newton CA. PMID: 37591536; PMCID: PMC10695771.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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An interleukin 6 responsive plasma cell signature is associated with disease progression in systemic sclerosis interstitial lung disease. iScience. 2023 Nov 17; 26(11):108133.
Jia G, Ramalingam TR, Heiden JV, Gao X, DePianto D, Morshead KB, Modrusan Z, Ramamoorthi N, Wolters P, Lin C, Khanna D, Arron JR. PMID: 37867940; PMCID: PMC10585397.
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Short airway telomeres are associated with primary graft dysfunction and chronic lung allograft dysfunction. J Heart Lung Transplant. 2023 12; 42(12):1700-1709.
Greenland JR, Guo R, Lee S, Tran L, Kapse B, Kukreja J, Hays SR, Golden JA, Calabrese DR, Singer JP, Wolters PJ. PMID: 37648073; PMCID: PMC10858720.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Targeted alveolar regeneration with Frizzled-specific agonists. Cell. 2023 07 06; 186(14):2995-3012.e15.
Nabhan AN, Webster JD, Adams JJ, Blazer L, Everrett C, Eidenschenk C, Arlantico A, Fleming I, Brightbill HD, Wolters PJ, Modrusan Z, Seshagiri S, Angers S, Sidhu SS, Newton K, Arron JR, Dixit VM. PMID: 37321220.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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PCSK6 and Survival in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2023 06 01; 207(11):1515-1524.
Oldham JM, Allen RJ, Lorenzo-Salazar JM, Molyneaux PL, Ma SF, Joseph C, Kim JS, Guillen-Guio B, Hernández-Beeftink T, Kropski JA, Huang Y, Lee CT, Adegunsoye A, Pugashetti JV, Linderholm AL, Vo V, Strek ME, Jou J, Muñoz-Barrera A, Rubio-Rodriguez LA, Hubbard R, Hirani N, Whyte MKB, Hart S, Nicholson AG, Lancaster L, Parfrey H, Rassl D, Wallace W, Valenzi E, Zhang Y, Mychaleckyj J, Stockwell A, Kaminski N, Wolters PJ, Molina-Molina M, Banovich NE, Fahy WA, Martinez FJ, Hall IP, Tobin MD, Maher TM, Blackwell TS, Yaspan BL, Jenkins RG, Flores C, Wain LV, Noth I. PMID: 36780644; PMCID: PMC10263132.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Protein biomarkers of disease progression in patients with systemic sclerosis associated interstitial lung disease. Sci Rep. 2023 05 27; 13(1):8645.
Cerro-Chiang G, Ayres M, Rivas A, Romero T, Parker SJ, Mastali M, Elashoff D, Chen P, Van Eyk JE, Wolters PJ, Boin F, Zaman T. PMID: 37244972; PMCID: PMC10224939.
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1 Fields:
Translation:
Humans
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Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants. Am J Respir Crit Care Med. 2023 05 01; 207(9):1194-1202.
Peljto AL, Blumhagen RZ, Walts AD, Cardwell J, Powers J, Corte TJ, Dickinson JL, Glaspole I, Moodley YP, Vasakova MK, Bendstrup E, Davidsen JR, Borie R, Crestani B, Dieude P, Bonella F, Costabel U, Gudmundsson G, Donnelly SC, Egan J, Henry MT, Keane MP, Kennedy MP, McCarthy C, McElroy AN, Olaniyi JA, O'Reilly KMA, Richeldi L, Leone PM, Poletti V, Puppo F, Tomassetti S, Luzzi V, Kokturk N, Mogulkoc N, Fiddler CA, Hirani N, Jenkins RG, Maher TM, Molyneaux PL, Parfrey H, Braybrooke R, Blackwell TS, Jackson PD, Nathan SD, Porteous MK, Brown KK, Christie JD, Collard HR, Eickelberg O, Foster EE, Gibson KF, Glassberg M, Kass DJ, Kropski JA, Lederer D, Linderholm AL, Loyd J, Mathai SK, Montesi SB, Noth I, Oldham JM, Palmisciano AJ, Reichner CA, Rojas M, Roman J, Schluger N, Shea BS, Swigris JJ, Wolters PJ, Zhang Y, Prele CMA, Enghelmayer JI, Otaola M, Ryerson CJ, Salinas M, Sterclova M, Gebremariam TH, Myllärniemi M, Carbone RG, Furusawa H, Hirose M, Inoue Y, Miyazaki Y, Ohta K, Ohta S, Okamoto T, Kim DS, Pardo A, Selman M, Aranda AU, Park MS, Park JS, Song JW, Molina-Molina M, Planas-Cerezales L, Westergren-Thorsson G, Smith AV, Manichaikul AW, Kim JS, Rich SS, Oelsner EC, Barr RG, Rotter JI, Dupuis J, O'Connor G, Vasan RS, Cho MH, Silverman EK, Schwarz MI, Steele MP, Lee JS, Yang IV, Fingerlin TE, Schwartz DA. PMID: 36602845; PMCID: PMC10161752.
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14 Fields:
Translation:
Humans
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Inhibition of MRTF activation as a clinically achievable anti-fibrotic mechanism for pirfenidone. Eur Respir J. 2023 04; 61(4).
Ma HY, Vander Heiden JA, Uttarwar S, Xi Y, N'Diaye EN, LaCanna R, Caplazi P, Gierke S, Moffat J, Wolters PJ, Ding N. PMID: 36585256; PMCID: PMC10133585.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Identification of a Genetic Susceptibility Locus for Idiopathic Pulmonary Fibrosis in the 16p Subtelomere Using Whole-Genome Sequencing. Am J Respir Crit Care Med. 2023 04 01; 207(7):941-944.
Donoghue LJ, Stockwell AD, Neighbors M, Sheng RX, Prabhakaran R, Wolters PJ, Lancaster LH, Kropski JA, Blackwell TS, McCarthy MI, Yaspan BL. PMID: 36603154; PMCID: PMC10111979.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Interstitial Lung Disease in Veterans: Leveraging Big Data to Bridge Evidence and Practice Gaps. Ann Am Thorac Soc. 2023 04; 20(4):504-507.
Kaul B, Petersen LA, Rosas IO, Lee JS, Martinez FJ, Bandi VD, Helmer DA, Wolters PJ, Collard HR, Whooley MA. PMID: 36623290.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts. Nat Commun. 2023 03 17; 14(1):1489.
Adegunsoye A, Newton CA, Oldham JM, Ley B, Lee CT, Linderholm AL, Chung JH, Garcia N, Zhang D, Vij R, Guzy R, Jablonski R, Bag R, Voogt RS, Ma SF, Sperling AI, Raghu G, Martinez FJ, Strek ME, Wolters PJ, Garcia CK, Pierce BL, Noth I. PMID: 36932145; PMCID: PMC10023792.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Evaluation of Pulmonary Fibrosis Outcomes by Race and Ethnicity in US Adults. JAMA Netw Open. 2023 03 01; 6(3):e232427.
Adegunsoye A, Freiheit E, White EN, Kaul B, Newton CA, Oldham JM, Lee CT, Chung J, Garcia N, Ghodrati S, Vij R, Jablonski R, Flaherty KR, Wolters PJ, Garcia CK, Strek ME. PMID: 36897590; PMCID: PMC10984340.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir. Immunity. 2023 03 14; 56(3):576-591.e10.
Wang C, Hyams B, Allen NC, Cautivo K, Monahan K, Zhou M, Dahlgren MW, Lizama CO, Matthay M, Wolters P, Molofsky AB, Peng T. PMID: 36822205; PMCID: PMC10578134.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Diffuse lung involvement in rheumatoid arthritis: a respiratory physician's perspective. Chin Med J (Engl). 2023 Feb 05; 136(3):280-286.
Huang H, Chen R, Shao C, Xu Z, Wolters PJ. PMID: 36689640; PMCID: PMC10106218.
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1 Fields:
Translation:
Humans
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Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 11 15; 206(10):1259-1270.
Borie R, Cardwell J, Konigsberg IR, Moore CM, Zhang W, Sasse SK, Gally F, Dobrinskikh E, Walts A, Powers J, Brancato J, Rojas M, Wolters PJ, Brown KK, Blackwell TS, Nakanishi T, Richards JB, Gerber AN, Fingerlin TE, Sachs N, Pulit SL, Zappala Z, Schwartz DA, Yang IV. PMID: 35816432; PMCID: PMC9746850.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis. Cell Metab. 2022 09 06; 34(9):1377-1393.e8.
Xi Y, LaCanna R, Ma HY, N'Diaye EN, Gierke S, Caplazi P, Sagolla M, Huang Z, Lucio L, Arlantico A, Jeet S, Brightbill H, Emson C, Wong A, Morshead KB, DePianto DJ, Roose-Girma M, Yu C, Tam L, Jia G, Ramalingam TR, Marsters S, Ashkenazi A, Kim SH, Kelly R, Wu S, Wolters PJ, Feldstein AE, Vander Heiden JA, Ding N. PMID: 35987202.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange. Dev Cell. 2022 07 11; 57(13):1566-1581.e7.
Zhang K, Yao E, Wang SA, Chuang E, Wong J, Minichiello L, Schroeder A, Eckalbar W, Wolters PJ, Chuang PT. PMID: 35714603; PMCID: PMC9308505.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis. JCI Insight. 2022 05 23; 7(10).
Wilson C, Mertens TC, Shivshankar P, Bi W, Collum SD, Wareing N, Ko J, Weng T, Naikawadi RP, Wolters PJ, Maire P, Jyothula SS, Thandavarayan RA, Ren D, Elrod ND, Wagner EJ, Huang HJ, Dickey BF, Ford HL, Karmouty-Quintana H. PMID: 35420997; PMCID: PMC9220956.
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3 Fields:
Translation:
Animals
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Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria. Elife. 2022 04 06; 11.
Zhang K, Yao E, Chen B, Chuang E, Wong J, Seed RI, Nishimura SL, Wolters PJ, Chuang PT. PMID: 35384838; PMCID: PMC9183236.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Impaired CD8+ T Cell Proliferation to Alloantigens in Lung Transplant Recipients with Idiopathic Pulmonary Fibrosis is Associated with P53 Upregulation. The Journal of Heart and Lung Transplantation. 2022 Apr 1; 41(4):s182.
Wang WP, Leung LJ, Lam LA, Lee LS, Calabrese CD, Hays HS, Golden GJ, Kukreja KJ, Singer SJ, Wolters WP, Tang TQ, Greenland GJ. .
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Genetically increased circulating FUT3 level leads to reduced risk of idiopathic pulmonary fibrosis: a Mendelian randomisation study. Eur Respir J. 2022 02; 59(2).
Nakanishi T, Cerani A, Forgetta V, Zhou S, Allen RJ, Leavy OC, Koido M, Assayag D, Jenkins RG, Wain LV, Yang IV, Lathrop GM, Wolters PJ, Schwartz DA, Richards JB. PMID: 34172473; PMCID: PMC8828995.
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5 Fields:
Translation:
Humans
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A simple method to generate human airway epithelial organoids with externally orientated apical membranes. Am J Physiol Lung Cell Mol Physiol. 2022 03 01; 322(3):L420-L437.
Boecking CA, Walentek P, Zlock LT, Sun DI, Wolters PJ, Ishikawa H, Jin BJ, Haggie PM, Marshall WF, Verkman AS, Finkbeiner WE. PMID: 35080188; PMCID: PMC8917940.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Proteomic biomarkers of progressive fibrosing interstitial lung disease: a multicentre cohort analysis. Lancet Respir Med. 2022 06; 10(6):593-602.
Bowman WS, Newton CA, Linderholm AL, Neely ML, Pugashetti JV, Kaul B, Vo V, Echt GA, Leon W, Shah RJ, Huang Y, Garcia CK, Wolters PJ, Oldham JM. PMID: 35063079; PMCID: PMC9177713.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma. Sci Transl Med. 2022 01 12; 14(627):eabf8188.
Headland SE, Dengler HS, Xu D, Teng G, Everett C, Ratsimandresy RA, Yan D, Kang J, Ganeshan K, Nazarova EV, Gierke S, Wedeles CJ, Guidi R, DePianto DJ, Morshead KB, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Klementowicz JE, Shi Y, Wang J, Bevers J, Ramirez-Carrozzi V, Pappu R, Abbas A, Vander Heiden J, Choy DF, Yadav R, Modrusan Z, Panettieri RA, Koziol-White C, Jester WF, Jenkins BJ, Cao Y, Clarke C, Austin C, Lafkas D, Xu M, Wolters PJ, Arron JR, West NR, Wilson MS. PMID: 35020406.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis. Thorax. 2022 05; 77(5):508-510.
Furusawa H, Peljto AL, Walts AD, Cardwell J, Molyneaux PL, Lee JS, Fernández Pérez ER, Wolters PJ, Yang IV, Schwartz DA. PMID: 34996848; PMCID: PMC9013199.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Cut from the Same Cloth: Similarities between Hypersensitivity Pneumonitis and Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 01 01; 205(1):4-6.
Yang MM, Wolters PJ. PMID: 34748715; PMCID: PMC8865579.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells. Nat Cell Biol. 2022 01; 24(1):10-23.
Kathiriya JJ, Wang C, Zhou M, Brumwell A, Cassandras M, Le Saux CJ, Cohen M, Alysandratos KD, Wang B, Wolters P, Matthay M, Kotton DN, Chapman HA, Peng T. PMID: 34969962; PMCID: PMC8761168.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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The prognostic role of matrix metalloproteinase-7 in scleroderma-associated interstitial lung disease. Eur Respir J. 2021 12; 58(6).
Matson SM, Lee SJ, Peterson RA, Achtar-Zadeh NA, Boin F, Wolters PJ, Lee JS. PMID: 34588190; PMCID: PMC9724002.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Molecular programs of fibrotic change in aging human lung. Nat Commun. 2021 11 02; 12(1):6309.
Lee S, Islam MN, Boostanpour K, Aran D, Jin G, Christenson S, Matthay MA, Eckalbar WL, DePianto DJ, Arron JR, Magee L, Bhattacharya S, Matsumoto R, Kubota M, Farber DL, Bhattacharya J, Wolters PJ, Bhattacharya M. PMID: 34728633; PMCID: PMC8563941.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Lung Transplant Recipients with Idiopathic Pulmonary Fibrosis Have Impaired Alloreactive Immune Responses. The Journal of Heart and Lung Transplantation. 2021 Nov 1.
Wang WP, Leung LJ, Lam LA, Lee LS, Calabrese CD, Hays HS, Golden GJ, Kukreja KJ, Singer SJ, Wolters WP, Tang TQ, Greenland GJ. .
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Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF. Respir Res. 2021 Oct 19; 22(1):265.
Decaris ML, Schaub JR, Chen C, Cha J, Lee GG, Rexhepaj M, Ho SS, Rao V, Marlow MM, Kotak P, Budi EH, Hooi L, Wu J, Fridlib M, Martin SP, Huang S, Chen M, Muñoz M, Hom TF, Wolters PJ, Desai TJ, Rock F, Leftheris K, Morgans DJ, Lepist EI, Andre P, Lefebvre EA, Turner SM. PMID: 34666752; PMCID: PMC8524858.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Treatment of fibrotic interstitial lung disease: current approaches and future directions. Lancet. 2021 10 16; 398(10309):1450-1460.
Johannson KA, Chaudhuri N, Adegunsoye A, Wolters PJ. PMID: 34499866.
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26 Fields:
Translation:
Humans
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Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates. Ann Am Thorac Soc. 2021 09; 18(9):1464-1474.
Maheshwari JA, Kolaitis NA, Anderson MR, Benvenuto L, Gao Y, Katz PP, Greenland J, Wolters PJ, Covinsky K, Hays SR, Kukreja J, Calabrese DR, Venado A, Shah RJ, Leard LE, Trinh B, Huang CY, Glidden D, Kleinhenz ME, Golden JA, Sutter N, Tietje-Ulrich G, Criner RN, Arcasoy SM, Christie JD, Diamond J, Singer JP. PMID: 33565917; PMCID: PMC8489868.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis. Sci Transl Med. 2021 08 04; 13(605).
Sun T, Huang Z, Liang WC, Yin J, Lin WY, Wu J, Vernes JM, Lutman J, Caplazi P, Jeet S, Wong T, Wong M, DePianto DJ, Morshead KB, Sun KH, Modrusan Z, Vander Heiden JA, Abbas AR, Zhang H, Xu M, N'Diaye EN, Roose-Girma M, Wolters PJ, Yadav R, Sukumaran S, Ghilardi N, Corpuz R, Emson C, Meng YG, Ramalingam TR, Lupardus P, Brightbill HD, Seshasayee D, Wu Y, Arron JR. PMID: 34349032.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimals
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Peripheral blood leucocyte telomere length is associated with progression of interstitial lung disease in systemic sclerosis. Thorax. 2021 12; 76(12):1186-1192.
Liu S, Chung MP, Ley B, French S, Elicker BM, Fiorentino DF, Chung LS, Boin F, Wolters PJ. PMID: 34272332; PMCID: PMC9262637.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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MUC5B promoter variant rs35705950 and rheumatoid arthritis associated interstitial lung disease survival and progression. Semin Arthritis Rheum. 2021 10; 51(5):996-1004.
Juge PA, Solomon JJ, van Moorsel CHM, Garofoli R, Lee JS, Louis-Sydney F, Rojas-Serrano J, González-Pérez MI, Mejia M, Buendia-Roldán I, Falfán-Valencia R, Ambrocio-Ortiz E, Manali E, Papiris SA, Karageorgas T, Boumpas D, Antoniou KM, Sidiropoulos P, Trachalaki A, van der Vis JJ, Jamnitski A, Grutters JC, Kannengiesser C, Borie R, Kawano-Dourado L, Wemeau-Stervinou L, Flipo RM, Nunes H, Uzunhan Y, Valeyre D, Saidenberg-Kermanac'h N, Boissier MC, Richez C, Schaeverbeke T, Doyle T, Wolters PJ, Debray MP, Boileau C, Porcher R, Schwartz DA, Crestani B, Dieudé P. PMID: 34411838.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Invariant Natural Killer T cells coordinate removal of senescent cells. Med. 2021 08 13; 2(8):938-950.
Arora S, Thompson PJ, Wang Y, Bhattacharyya A, Apostolopoulou H, Hatano R, Naikawadi RP, Shah A, Wolters PJ, Koliwad S, Bhattacharya M, Bhushan A. PMID: 34617070; PMCID: PMC8491998.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Molecular mapping of interstitial lung disease reveals a phenotypically distinct senescent basal epithelial cell population. JCI Insight. 2021 04 22; 6(8).
DePianto DJ, Heiden JAV, Morshead KB, Sun KH, Modrusan Z, Teng G, Wolters PJ, Arron JR. PMID: 33705361; PMCID: PMC8119199.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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MAV(S)erick mitochondria: an unconventional role for mitochondrial antiviral signalling protein in pulmonary fibrosis. Eur Respir J. 2021 04; 57(4).
Naikawadi RP, Wolters PJ. PMID: 33858852.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Molecular markers of telomere dysfunction and senescence are common findings in the usual interstitial pneumonia pattern of lung fibrosis. Histopathology. 2021 Jul; 79(1):67-76.
Lee JS, La J, Aziz S, Dobrinskikh E, Brownell R, Jones KD, Achtar-Zadeh N, Green G, Elicker BM, Golden JA, Matthay MA, Kukreja J, Schwartz DA, Wolters PJ. PMID: 33432658; PMCID: PMC8195814.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Leukocyte telomere length and mycophenolate therapy in chronic hypersensitivity pneumonitis. Eur Respir J. 2021 03; 57(3).
Adegunsoye A, Morisset J, Newton CA, Oldham JM, Vittinghoff E, Linderholm AL, Strek ME, Noth I, Garcia CK, Wolters PJ, Ley B. PMID: 33122338; PMCID: PMC8104021.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Autoantibodies targeting telomere-associated proteins in systemic sclerosis. Ann Rheum Dis. 2021 07; 80(7):912-919.
Adler BL, Boin F, Wolters PJ, Bingham CO, Shah AA, Greider C, Casciola-Rosen L, Rosen A. PMID: 33495152; PMCID: PMC8217217.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Blocking LOXL2 and TGFβ1 signalling induces collagen I turnover in precision-cut lung slices derived from patients with idiopathic pulmonary fibrosis. Thorax. 2021 07; 76(7):729-732.
Wei Y, Dong W, Jackson J, Ho TC, Le Saux CJ, Brumwell A, Li X, Klesney-Tait J, Cohen ML, Wolters PJ, Chapman HA. PMID: 33472968; PMCID: PMC8222054.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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The Pulmonary Fibrosis Foundation Patient Registry. Rationale, Design, and Methods. Ann Am Thorac Soc. 2020 12; 17(12):1620-1628.
Wang BR, Edwards R, Freiheit EA, Ma Y, Burg C, de Andrade J, Lancaster L, Lindell K, Nathan SD, Raghu G, Gibson K, Gulati M, Mason W, Noth I, Schmidt B, Spino C, Staszak S, Stauffer J, Wolters PJ, Cosgrove GP, Flaherty KR. PMID: 32776789.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
Extracellular BMP1 is the major proteinase for COOH-terminal proteolysis of type I procollagen in lung fibroblasts. Am J Physiol Cell Physiol. 2021 02 01; 320(2):C162-C174.
N'Diaye EN, Cook R, Wang H, Wu P, LaCanna R, Wu C, Ye Z, Seshasayee D, Hazen M, Lin W, Tyagi T, Hotzel I, Tam L, Newman R, Roose-Girma M, Wolters PJ, Ding N. PMID: 33206546.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis. Cell Rep Med. 2020 11 17; 1(8):100140.
Gao X, Jia G, Guttman A, DePianto DJ, Morshead KB, Sun KH, Ramamoorthi N, Vander Heiden JA, Modrusan Z, Wolters PJ, Jahreis A, Arron JR, Khanna D, Ramalingam TR. PMID: 33294861; PMCID: PMC7691442.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCellsCTClinical Trials
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Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures. Am J Respir Crit Care Med. 2020 11 15; 202(10):1430-1444.
Furusawa H, Cardwell JH, Okamoto T, Walts AD, Konigsberg IR, Kurche JS, Bang TJ, Schwarz MI, Brown KK, Kropski JA, Rojas M, Cool CD, Lee JS, Wolters PJ, Yang IV, Schwartz DA. PMID: 32602730; PMCID: PMC7667907.
View in:
PubMed Mentions:
38 Fields:
Translation:
Humans
-
Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol. 2020 11; 22(11):1295-1306.
Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T. PMID: 33046884; PMCID: PMC7642162.
View in:
PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury. Am J Pathol. 2020 12; 190(12):2355-2375.
Baluk P, Naikawadi RP, Kim S, Rodriguez F, Choi D, Hong YK, Wolters PJ, McDonald DM. PMID: 33039355; PMCID: PMC7734600.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Essential Components of an Interstitial Lung Disease Clinic: Results From a Delphi Survey and Patient Focus Group Analysis. Chest. 2021 04; 159(4):1517-1530.
Graney BA, He C, Marll M, Matson S, Bianchi P, Cosgrove GP, Lee JS, PFF CCN Delphi Collaborators. PMID: 33031832; PMCID: PMC7534733.
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PubMed Mentions:
8 Fields:
Translation:
Humans
-
Airway Epithelial Telomere Dysfunction Drives Remodeling Similar to Chronic Lung Allograft Dysfunction. Am J Respir Cell Mol Biol. 2020 10; 63(4):490-501.
Naikawadi RP, Green G, Jones KD, Achtar-Zadeh N, Mieleszko JE, Arnould I, Kukreja J, Greenland JR, Wolters PJ. PMID: 32551854; PMCID: PMC7528921.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Telomere length in patients with unclassifiable interstitial lung disease: a cohort study. Eur Respir J. 2020 08; 56(2).
Ley B, Liu S, Elicker BM, Henry TS, Vittinghoff E, Golden JA, Jones KD, Wolters PJ. PMID: 32341108.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Age-dependent regulation of cell-mediated collagen turnover. JCI Insight. 2020 05 21; 5(10).
Podolsky MJ, Yang CD, Valenzuela CL, Datta R, Huang SK, Nishimura SL, Dallas SL, Wolters PJ, Le Saux CJ, Atabai K. PMID: 32315288; PMCID: PMC7259530.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis. Elife. 2020 05 12; 9.
Zhang K, Yao E, Lin C, Chou YT, Wong J, Li J, Wolters PJ, Chuang PT. PMID: 32394892; PMCID: PMC7217702.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Long-term ozone exposure is positively associated with telomere length in critically ill patients. Environ Int. 2020 08; 141:105780.
Wang C, Wolters PJ, Calfee CS, Liu S, Balmes JR, Zhao Z, Koyama T, Ware LB. PMID: 32417614; PMCID: PMC7535086.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCellsPHPublic Health
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Frailty after lung transplantation is associated with impaired health-related quality of life and mortality. Thorax. 2020 08; 75(8):669-678.
Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD, Singer JP. PMID: 32376733; PMCID: PMC8023537.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Diaphragmatic Atrophy May Limit Progression of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2020 05 01; 201(9):e72-e73.
Venado A, Witt LJ, Kallianos K, Wolters PJ. PMID: 31825660.
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PubMed Mentions: Fields:
Translation:
Humans
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Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nat Commun. 2020 04 21; 11(1):1920.
Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, Adams TS, Schupp JC, Poli SD, Rosas IO, Kaminski N, Matthay MA, Wolters PJ, Sheppard D. PMID: 32317643; PMCID: PMC7174390.
View in:
PubMed Mentions:
241 Fields:
Translation:
HumansAnimalsCells
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Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis. N Engl J Med. 2020 03 12; 382(11):1068-1070.
Chapman HA, Wei Y, Montas G, Leong D, Golden JA, Trinh BN, Wolters PJ, Le Saux CJ, Jones KD, Hills NK, Foster E, Oldham JM, Linderholm AL, Kotak P, Decaris M, Turner S, Song JW. PMID: 32160670; PMCID: PMC7297220.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
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A Systematically Derived Exposure Assessment Instrument for Chronic Hypersensitivity Pneumonitis. Chest. 2020 06; 157(6):1506-1512.
Barnes H, Morisset J, Molyneaux P, Westall G, Glaspole I, Collard HR, CHP Exposure Assessment Collaborators. PMID: 31958445; PMCID: PMC7268442.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
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Peripheral blood leukocyte telomere length is associated with survival of sepsis patients. Eur Respir J. 2020 01; 55(1).
Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ. PMID: 31619475; PMCID: PMC7359873.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Interaction Between Epithelial and Mesenchymal Cells in Interstitial Lung Disease. . 2020 Jan 1.
Cohen CM, Wolters WP. .
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Publisher Site Mentions:
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Rare Protein-Altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis. Am J Respir Crit Care Med. 2019 11 01; 200(9):1154-1163.
Ley B, Torgerson DG, Oldham JM, Adegunsoye A, Liu S, Li J, Elicker BM, Henry TS, Golden JA, Jones KD, Dressen A, Yaspan BL, Arron JR, Noth I, Hoffmann TJ, Wolters PJ. PMID: 31268371; PMCID: PMC6888660.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Regulatory T cells in skin are uniquely poised to suppress profibrotic immune responses. Sci Immunol. 2019 09 06; 4(39).
Kalekar LA, Cohen JN, Prevel N, Sandoval PM, Mathur AN, Moreau JM, Lowe MM, Nosbaum A, Wolters PJ, Haemel A, Boin F, Rosenblum MD. PMID: 31492709; PMCID: PMC6848056.
View in:
PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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Oxygen in patients with fibrotic interstitial lung disease: an international Delphi survey. Eur Respir J. 2019 08; 54(2).
Lim RK, Humphreys C, Morisset J, Holland AE, Johannson KA, O2 Delphi Collaborators. PMID: 31097522.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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A nonlinear relationship between visceral adipose tissue and frailty in adult lung transplant candidates. Am J Transplant. 2019 11; 19(11):3155-3161.
Anderson MR, Kolaitis NA, Gao Y, Kukreja J, Greenland J, Hays S, Wolters P, Golden J, Diamond J, Palmer S, Arcasoy S, Udupa J, Christie JD, Lederer DJ, Singer JP. PMID: 31278829; PMCID: PMC7863776.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
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Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 07 15; 200(2):199-208.
Moore C, Blumhagen RZ, Yang IV, Walts A, Powers J, Walker T, Bishop M, Russell P, Vestal B, Cardwell J, Markin CR, Mathai SK, Schwarz MI, Steele MP, Lee J, Brown KK, Loyd JE, Crapo JD, Silverman EK, Cho MH, James JA, Guthridge JM, Cogan JD, Kropski JA, Swigris JJ, Bair C, Kim DS, Ji W, Kim H, Song JW, Maier LA, Pacheco KA, Hirani N, Poon AS, Li F, Jenkins RG, Braybrooke R, Saini G, Maher TM, Molyneaux PL, Saunders P, Zhang Y, Gibson KF, Kass DJ, Rojas M, Sembrat J, Wolters PJ, Collard HR, Sundy JS, O'Riordan T, Strek ME, Noth I, Ma SF, Porteous MK, Kreider ME, Patel NB, Inoue Y, Hirose M, Arai T, Akagawa S, Eickelberg O, Fernandez IE, Behr J, Mogulkoc N, Corte TJ, Glaspole I, Tomassetti S, Ravaglia C, Poletti V, Crestani B, Borie R, Kannengiesser C, Parfrey H, Fiddler C, Rassl D, Molina-Molina M, Machahua C, Worboys AM, Gudmundsson G, Isaksson HJ, Lederer DJ, Podolanczuk AJ, Montesi SB, Bendstrup E, Danchel V, Selman M, Pardo A, Henry MT, Keane MP, Doran P, Vašáková M, Sterclova M, Ryerson CJ, Wilcox PG, Okamoto T, Furusawa H, Miyazaki Y, Laurent G, Baltic S, Prele C, Moodley Y, Shea BS, Ohta K, Suzukawa M, Narumoto O, Nathan SD, Venuto DC, Woldehanna ML, Kokturk N, de Andrade JA, Luckhardt T, Kulkarni T, Bonella F, Donnelly SC, McElroy A, Armstong ME, Aranda A, Carbone RG, Puppo F, Beckman KB, Nickerson DA, Fingerlin TE, Schwartz DA. PMID: 31034279; PMCID: PMC6635791.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Prevalence and Clinical Significance of Antineutrophil Cytoplasmic Antibodies in North American Patients With Idiopathic Pulmonary Fibrosis. Chest. 2019 10; 156(4):715-723.
Liu GY, Ventura IB, Achtar-Zadeh N, Elicker BM, Jones KD, Wolters PJ, Collard HR, Adegunsoye A, Strek ME, Ley B. PMID: 31181198; PMCID: PMC6859239.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Pulmonary physiology is poorly associated with radiological extent of disease in systemic sclerosis-associated interstitial lung disease. Eur Respir J. 2019 05; 53(5).
Jhajj A, Gill HP, Hague CJ, Murphy D, Elicker B, Soon J, Sulaiman N, Castillo-Saldana D, Wilcox PG, Dunne J, Lee JS, Wolters PJ, Ley B, Jones KD, Morisset J, Ryerson CJ. PMID: 30846470.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Significance of bronchiolocentric fibrosis in patients with histopathological usual interstitial pneumonia. Histopathology. 2019 Jun; 74(7):1088-1097.
Tanizawa K, Ley B, Vittinghoff E, Elicker BM, Henry TS, Wolters PJ, Brownell R, Liu S, Collard HR, Jones KD. PMID: 30742318; PMCID: PMC6506377.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Telomere length and genetic variant associations with interstitial lung disease progression and survival. Eur Respir J. 2019 04; 53(4).
Newton CA, Oldham JM, Ley B, Anand V, Adegunsoye A, Liu G, Batra K, Torrealba J, Kozlitina J, Glazer C, Strek ME, Wolters PJ, Noth I, Garcia CK. PMID: 30635297; PMCID: PMC6612265.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Molecular endpoints for establishing target engagement by novel idiopathic pulmonary fibrosis therapies. Eur Respir J. 2019 03; 53(3).
Wolters PJ, Cottin V. PMID: 30886027.
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PubMed Mentions: Fields:
Translation:
Humans
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Association between greenhouse working exposure and bronchial asthma: A pilot, cross-sectional survey of 5,420 greenhouse farmers from northeast China. J Occup Environ Hyg. 2019 Apr; 16(4):286-293.
Liu S, Wolters PJ, Zhang Y, Zhao M, Liu D, Wang L, Zhao G, Mao S, Wu L, Zhao H, Wang X. PMID: 30822226.
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PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
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Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol. 2019 02; 20(2):163-172.
Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi RP, Wolters PJ, Abate AR, Butte AJ, Bhattacharya M. PMID: 30643263; PMCID: PMC6340744.
View in:
PubMed Mentions:
1664 Fields:
Translation:
HumansAnimalsCells
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Increased Extracellular Vesicles Mediate WNT5A Signaling in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2018 12 15; 198(12):1527-1538.
Martin-Medina A, Lehmann M, Burgy O, Hermann S, Baarsma HA, Wagner DE, De Santis MM, Ciolek F, Hofer TP, Frankenberger M, Aichler M, Lindner M, Gesierich W, Guenther A, Walch A, Coughlan C, Wolters P, Lee JS, Behr J, Königshoff M. PMID: 30044642.
View in:
PubMed Mentions:
94 Fields:
Translation:
HumansCells
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Pirfenidone in the kaleidoscope: reflecting mechanisms through different angles. Eur Respir J. 2018 11; 52(5).
Tzouvelekis A, Wolters PJ. PMID: 30467176.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Histopathological and molecular analysis of idiopathic pulmonary fibrosis lungs from patients treated with pirfenidone or nintedanib. Histopathology. 2019 Jan; 74(2):341-349.
Zhang Y, Jones KD, Achtar-Zadeh N, Green G, Kukreja J, Xu B, Wolters PJ. PMID: 30152895.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease. N Engl J Med. 2018 12 06; 379(23):2209-2219.
Juge PA, Lee JS, Ebstein E, Furukawa H, Dobrinskikh E, Gazal S, Kannengiesser C, Ottaviani S, Oka S, Tohma S, Tsuchiya N, Rojas-Serrano J, González-Pérez MI, Mejía M, Buendía-Roldán I, Falfán-Valencia R, Ambrocio-Ortiz E, Manali E, Papiris SA, Karageorgas T, Boumpas D, Antoniou K, van Moorsel CHM, van der Vis J, de Man YA, Grutters JC, Wang Y, Borie R, Wemeau-Stervinou L, Wallaert B, Flipo RM, Nunes H, Valeyre D, Saidenberg-Kermanac'h N, Boissier MC, Marchand-Adam S, Frazier A, Richette P, Allanore Y, Sibilia J, Dromer C, Richez C, Schaeverbeke T, Lioté H, Thabut G, Nathan N, Amselem S, Soubrier M, Cottin V, Clément A, Deane K, Walts AD, Fingerlin T, Fischer A, Ryu JH, Matteson EL, Niewold TB, Assayag D, Gross A, Wolters P, Schwarz MI, Holers M, Solomon JJ, Doyle T, Rosas IO, Blauwendraat C, Nalls MA, Debray MP, Boileau C, Crestani B, Schwartz DA, Dieudé P. PMID: 30345907; PMCID: PMC6371965.
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PubMed Mentions:
190 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
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Laparoscopic anti-reflux surgery for the treatment of idiopathic pulmonary fibrosis (WRAP-IPF): a multicentre, randomised, controlled phase 2 trial. Lancet Respir Med. 2018 09; 6(9):707-714.
Raghu G, Pellegrini CA, Yow E, Flaherty KR, Meyer K, Noth I, Scholand MB, Cello J, Ho LA, Pipavath S, Lee JS, Lin J, Maloney J, Martinez FJ, Morrow E, Patti MG, Rogers S, Wolters PJ, Yates R, Anstrom KJ, Collard HR. PMID: 30100404.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCTClinical Trials
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Prognostic and predictive biomarkers for patients with idiopathic pulmonary fibrosis treated with pirfenidone: post-hoc assessment of the CAPACITY and ASCEND trials. Lancet Respir Med. 2018 08; 6(8):615-626.
Neighbors M, Cabanski CR, Ramalingam TR, Sheng XR, Tew GW, Gu C, Jia G, Peng K, Ray JM, Ley B, Wolters PJ, Collard HR, Arron JR. PMID: 30072107.
View in:
PubMed Mentions:
57 Fields:
Translation:
Humans
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Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study. Lancet Respir Med. 2018 08; 6(8):603-614.
Dressen A, Abbas AR, Cabanski C, Reeder J, Ramalingam TR, Neighbors M, Bhangale TR, Brauer MJ, Hunkapiller J, Reeder J, Mukhyala K, Cuenco K, Tom J, Cowgill A, Vogel J, Forrest WF, Collard HR, Wolters PJ, Kropski JA, Lancaster LH, Blackwell TS, Arron JR, Yaspan BL. PMID: 29891356; PMCID: PMC6487850.
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PubMed Mentions:
87 Fields:
Translation:
Humans
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Air Pollution Exposure Is Associated With Lower Lung Function, but Not Changes in Lung Function, in Patients With Idiopathic Pulmonary Fibrosis. Chest. 2018 07; 154(1):119-125.
Johannson KA, Vittinghoff E, Morisset J, Wolters PJ, Noth EM, Balmes JR, Collard HR. PMID: 29355549; PMCID: PMC6045778.
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PubMed Mentions:
38 Fields:
Translation:
HumansPHPublic Health
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Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic? Lancet Respir Med. 2018 02; 6(2):154-160.
Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G, Maher TM, Molina-Molina M, Noble PW, Raghu G, Richeldi L, Schwarz MI, Selman M, Wuyts WA, Schwartz DA. PMID: 29413083; PMCID: PMC5903445.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansCells
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Identification of Diagnostic Criteria for Chronic Hypersensitivity Pneumonitis: An International Modified Delphi Survey. Am J Respir Crit Care Med. 2018 04 15; 197(8):1036-1044.
Morisset J, Johannson KA, Jones KD, Wolters PJ, Collard HR, Walsh SLF, Ley B, HP Delphi Collaborators. PMID: 29172641; PMCID: PMC6839923.
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PubMed Mentions:
86 Fields:
Translation:
Humans
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The MUC5B promoter polymorphism and telomere length in patients with chronic hypersensitivity pneumonitis: an observational cohort-control study. Lancet Respir Med. 2017 08; 5(8):639-647.
Ley B, Newton CA, Arnould I, Elicker BM, Henry TS, Vittinghoff E, Golden JA, Jones KD, Batra K, Torrealba J, Garcia CK, Wolters PJ. PMID: 28648751; PMCID: PMC5555581.
View in:
PubMed Mentions:
114 Fields:
Translation:
HumansCells
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Mortality Risk Prediction in Scleroderma-Related Interstitial Lung Disease: The SADL Model. Chest. 2017 11; 152(5):999-1007.
Morisset J, Vittinghoff E, Elicker BM, Hu X, Le S, Ryu JH, Jones KD, Haemel A, Golden JA, Boin F, Ley B, Wolters PJ, King TE, Collard HR, Lee JS. PMID: 28629914; PMCID: PMC5812750.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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A recurring theme in pulmonary fibrosis genetics. Eur Respir J. 2017 05; 49(5).
Wolters PJ. PMID: 28495682.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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The performance of the GAP model in patients with rheumatoid arthritis associated interstitial lung disease. Respir Med. 2017 06; 127:51-56.
Morisset J, Vittinghoff E, Lee BY, Tonelli R, Hu X, Elicker BM, Ryu JH, Jones KD, Cerri S, Manfredi A, Sebastiani M, Gross AJ, Ley B, Wolters PJ, King TE, Kim DS, Collard HR, Lee JS. PMID: 28502419; PMCID: PMC5506836.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
-
CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis. Thorax. 2017 09; 72(9):780-787.
Jia G, Chandriani S, Abbas AR, DePianto DJ, N'Diaye EN, Yaylaoglu MB, Moore HM, Peng I, DeVoss J, Collard HR, Wolters PJ, Egen JG, Arron JR. PMID: 28250200.
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Pathologic Findings and Prognosis in a Large Prospective Cohort of Chronic Hypersensitivity Pneumonitis. Chest. 2017 09; 152(3):502-509.
Wang P, Jones KD, Urisman A, Elicker BM, Urbania T, Johannson KA, Assayag D, Lee J, Wolters PJ, Collard HR, Koth LL. PMID: 28223152.
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PubMed Mentions:
56 Fields:
Translation:
Humans
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The use of pretest probability increases the value of high-resolution CT in diagnosing usual interstitial pneumonia. Thorax. 2017 May; 72(5):424-429.
Brownell R, Moua T, Henry TS, Elicker BM, White D, Vittinghoff E, Jones KD, Urisman A, Aravena C, Johannson KA, Golden JA, King TE, Wolters PJ, Collard HR, Ley B. PMID: 28082530; PMCID: PMC5555580.
View in:
PubMed Mentions:
33 Fields:
Translation:
Humans
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Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity. JCI Insight. 2016 Dec 22; 1(21):e89073.
Lofgren S, Hinchcliff M, Carns M, Wood T, Aren K, Arroyo E, Cheung P, Kuo A, Valenzuela A, Haemel A, Wolters PJ, Gordon J, Spiera R, Assassi S, Boin F, Chung L, Fiorentino D, Utz PJ, Whitfield ML, Khatri P. PMID: 28018971; PMCID: PMC5161207.
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PubMed Mentions:
39 Fields:
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Use of Mycophenolate Mofetil or Azathioprine for the Management of Chronic Hypersensitivity Pneumonitis. Chest. 2017 03; 151(3):619-625.
Morisset J, Johannson KA, Vittinghoff E, Aravena C, Elicker BM, Jones KD, Fell CD, Manganas H, Dubé BP, Wolters PJ, Collard HR, Ryerson CJ, Ley B. PMID: 27816444; PMCID: PMC6026221.
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PubMed Mentions:
78 Fields:
Translation:
Humans
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Donor-Reactive Regulatory T Cell Frequency Increases During Acute Cellular Rejection of Lung Allografts. Transplantation. 2016 10; 100(10):2090-8.
Greenland JR, Wong CM, Ahuja R, Wang AS, Uchida C, Golden JA, Hays SR, Leard LE, Rajalingam R, Singer JP, Kukreja J, Wolters PJ, Caughey GH, Tang Q. PMID: 27077597; PMCID: PMC5030122.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis. JCI Insight. 2016 09 08; 1(14):e86704.
Naikawadi RP, Disayabutr S, Mallavia B, Donne ML, Green G, La JL, Rock JR, Looney MR, Wolters PJ. PMID: 27699234; PMCID: PMC5033906.
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PubMed Mentions:
133 Fields:
Translation:
AnimalsCells
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Brief Report: Whole-Exome Sequencing for Identification of Potential Causal Variants for Diffuse Cutaneous Systemic Sclerosis. Arthritis Rheumatol. 2016 09; 68(9):2257-62.
Mak AC, Tang PL, Cleveland C, Smith MH, Kari Connolly M, Katsumoto TR, Wolters PJ, Kwok PY, Criswell LA. PMID: 27111861; PMCID: PMC5568050.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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P131 Telomere Dysfunction in Alveolar Epithelial Cells Causes Pulmonary Fibrosis: Role for TRF1. QJM. 2016 Sep 1; 109(suppl_1):s67-s67.
Naikawadi NR, Disayabutr DS, Mallavia MB, Donne DM, Green GG, Rock RJ, Looney LM, Wolters WP. .
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Prediction of histopathologic usual interstitial pneumonia among ILD cases with a non-diagnostic high-resolution computed tomography scan. QJM. 2016 Sep 1; 109(suppl_1):s13-s13.
Brownell BR, Henry HT, Elicker EB, Vittinghoff VE, Jones JK, Urisman UA, Aravena-leon AC, Golden GJ, King KT, Wolters WP, Collard CH, Ley LB. .
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Publisher Site Mentions:
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P042 A tale of three cohorts: variability in the prognostic value of IPF biomarkers. QJM. 2016 Sep 1; 109(suppl_1):s35-s35.
DePianto DD, Jia JG, Abbas AA, Lewin-koh LN, Holweg HC, Kervitsky KD, Brown BK, Kondoh KY, Wolters WP, Collard CH, Arron AJ. .
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Publisher Site Mentions:
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‘Assessment of Prognostic and predictive properties of blood biomarkers in pivotal clinical studies of Pirfenidone’. QJM. 2016 Sep 1; 109(suppl_1):s15-s15.
Genentech GN, Cabanski CC, D.J. DD, Ramalingam RT, Tew TG, Jia JG, Abbas AA, Peng PK, Ray RJ, Palme PS, Dziadek DS, Ritter RM, Kirchgaessler KK, Ley LB, Wolters WP, Collard CH, Arron AJ. .
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Publisher Site Mentions:
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Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis. PLoS One. 2016; 11(8):e0158047.
Tatler AL, Goodwin AT, Gbolahan O, Saini G, Porte J, John AE, Clifford RL, Violette SM, Weinreb PH, Parfrey H, Wolters PJ, Gauldie J, Kolb M, Jenkins G. PMID: 27494713; PMCID: PMC4975449.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis. PLoS One. 2016; 11(6):e0158367.
Disayabutr S, Kim EK, Cha SI, Green G, Naikawadi RP, Jones KD, Golden JA, Schroeder A, Matthay MA, Kukreja J, Erle DJ, Collard HR, Wolters PJ. PMID: 27362652; PMCID: PMC4928999.
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PubMed Mentions:
72 Fields:
Translation:
HumansCells
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Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia. BMC Genet. 2016 06 07; 17(1):74.
Fingerlin TE, Zhang W, Yang IV, Ainsworth HC, Russell PH, Blumhagen RZ, Schwarz MI, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch DA, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Murphy E, Smith K, McKean D, Pedersen BS, Talbert J, Powers J, Markin CR, Beckman KB, Lathrop M, Freed B, Langefeld CD, Schwartz DA. PMID: 27266705; PMCID: PMC4895966.
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PubMed Mentions:
56 Fields:
Translation:
HumansCells
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A diagnostic model for chronic hypersensitivity pneumonitis. Thorax. 2016 10; 71(10):951-4.
Johannson KA, Elicker BM, Vittinghoff E, Assayag D, de Boer K, Golden JA, Jones KD, King TE, Koth LL, Lee JS, Ley B, Wolters PJ, Collard HR. PMID: 27245779; PMCID: PMC5530732.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression. J Biol Chem. 2016 Apr 29; 291(18):9540-53.
Tatler AL, Habgood A, Porte J, John AE, Stavrou A, Hodge E, Kerama-Likoko C, Violette SM, Weinreb PH, Knox AJ, Laurent G, Parfrey H, Wolters PJ, Wallace W, Alberti S, Nordheim A, Jenkins G. PMID: 26861876; PMCID: PMC4850293.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes. Sci Rep. 2016 Jan 22; 6:19755.
Withana NP, Ma X, McGuire HM, Verdoes M, van der Linden WA, Ofori LO, Zhang R, Li H, Sanman LE, Wei K, Yao S, Wu P, Li F, Huang H, Xu Z, Wolters PJ, Rosen GD, Collard HR, Zhu Z, Cheng Z, Bogyo M. PMID: 26797565; PMCID: PMC4726431.
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PubMed Mentions:
55 Fields:
Translation:
Animals
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Frailty Phenotypes, Disability, and Outcomes in Adult Candidates for Lung Transplantation. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1325-34.
Singer JP, Diamond JM, Gries CJ, McDonnough J, Blanc PD, Shah R, Dean MY, Hersh B, Wolters PJ, Tokman S, Arcasoy SM, Ramphal K, Greenland JR, Smith N, Heffernan P, Shah L, Shrestha P, Golden JA, Blumenthal NP, Huang D, Sonett J, Hays S, Oyster M, Katz PP, Robbins H, Brown M, Leard LE, Kukreja J, Bacchetta M, Bush E, D'Ovidio F, Rushefski M, Raza K, Christie JD, Lederer DJ. PMID: 26258797; PMCID: PMC4731703.
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PubMed Mentions:
84 Fields:
Translation:
Humans
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Interstitial lung diseases in the hospitalized patient. BMC Med. 2015 Sep 25; 13:245.
Disayabutr S, Calfee CS, Collard HR, Wolters PJ. PMID: 26407727; PMCID: PMC4584017.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Survival in interstitial pneumonia with features of autoimmune disease: a comparison of proposed criteria. Respir Med. 2015 Oct; 109(10):1326-31.
Assayag D, Kim EJ, Elicker BM, Jones KD, Golden JA, King TE, Koth LL, Shum AK, Wolters PJ, Collard HR, Lee JS. PMID: 26303338.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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The effect of bronchodilators on forced vital capacity measurement in patients with idiopathic pulmonary fibrosis. Respir Med. 2015 Aug; 109(8):1058-62.
Assayag D, Vittinghoff E, Ryerson CJ, Cocconcelli E, Tonelli R, Hu X, Elicker BM, Golden JA, Jones KD, King TE, Koth LL, Lee JS, Ley B, Shum AK, Wolters PJ, Ryu JH, Collard HR. PMID: 26140806; PMCID: PMC4522344.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Lung transplantation for hypersensitivity pneumonitis. Chest. 2015 Jun; 147(6):1558-1565.
Kern RM, Singer JP, Koth L, Mooney J, Golden J, Hays S, Greenland J, Wolters P, Ghio E, Jones KD, Leard L, Kukreja J, Blanc PD. PMID: 25412059; PMCID: PMC4451710.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Classification of usual interstitial pneumonia in patients with interstitial lung disease: assessment of a machine learning approach using high-dimensional transcriptional data. Lancet Respir Med. 2015 Jun; 3(6):473-82.
Kim SY, Diggans J, Pankratz D, Huang J, Pagan M, Sindy N, Tom E, Anderson J, Choi Y, Lynch DA, Steele MP, Flaherty KR, Brown KK, Farah H, Bukstein MJ, Pardo A, Selman M, Wolters PJ, Nathan SD, Colby TV, Myers JL, Katzenstein AL, Raghu G, Kennedy GC. PMID: 26003389.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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Transforming Growth Factor-β and Interleukin-1β Signaling Pathways Converge on the Chemokine CCL20 Promoter. J Biol Chem. 2015 Jun 05; 290(23):14717-28.
Brand OJ, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson AJ, Hill A, Jablons D, Wolters P, Lou J, Marks JD, Baron JL, Nishimura SL. PMID: 25918170; PMCID: PMC4505537.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Overexpression of inhibitor of DNA-binding 2 attenuates pulmonary fibrosis through regulation of c-Abl and Twist. Am J Pathol. 2015 Apr; 185(4):1001-11.
Yang J, Velikoff M, Agarwal M, Disayabutr S, Wolters PJ, Kim KK. PMID: 25661109; PMCID: PMC4380847.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Subacute onset of pulmonary langerhans cell histiocytosis with resolution after smoking cessation. Am J Respir Crit Care Med. 2014 Dec 01; 190(11):e64.
Wolters PJ, Elicker BM. PMID: 25436789.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Fibulin-1 predicts disease progression in patients with idiopathic pulmonary fibrosis. Chest. 2014 Oct; 146(4):1055-1063.
Jaffar J, Unger S, Corte TJ, Keller M, Wolters PJ, Richeldi L, Cerri S, Prêle CM, Hansbro PM, Argraves WS, Oliver RA, Oliver BG, Black JL, Burgess JK. PMID: 24832167; PMCID: PMC4188142.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis. Thorax. 2015 Jan; 70(1):48-56.
DePianto DJ, Chandriani S, Abbas AR, Jia G, N'Diaye EN, Caplazi P, Kauder SE, Biswas S, Karnik SK, Ha C, Modrusan Z, Matthay MA, Kukreja J, Collard HR, Egen JG, Wolters PJ, Arron JR. PMID: 25217476; PMCID: PMC4472447.
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PubMed Mentions:
128 Fields:
Translation:
HumansCells
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Dipeptidyl peptidase I controls survival from Klebsiella pneumoniae lung infection by processing surfactant protein D. Biochem Biophys Res Commun. 2014 Jul 18; 450(1):818-823.
Sutherland RE, Barry SS, Olsen JS, Salantes DB, Caughey GH, Wolters PJ. PMID: 24955853; PMCID: PMC4107110.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Selective targeting of TGF-β activation to treat fibroinflammatory airway disease. Sci Transl Med. 2014 Jun 18; 6(241):241ra79.
Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL. PMID: 24944194; PMCID: PMC4341974.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimals
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Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation. Lancet Respir Med. 2014 Jul; 2(7):557-65.
Stuart BD, Lee JS, Kozlitina J, Noth I, Devine MS, Glazer CS, Torres F, Kaza V, Girod CE, Jones KD, Elicker BM, Ma SF, Vij R, Collard HR, Wolters PJ, Garcia CK. PMID: 24948432; PMCID: PMC4136521.
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PubMed Mentions:
138 Fields:
Translation:
HumansCells
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Endogenously expressed IL-13Rα2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts. J Immunol. 2014 Jul 01; 193(1):111-9.
Chandriani S, DePianto DJ, N'Diaye EN, Abbas AR, Jackman J, Bevers J, Ramirez-Carrozzi V, Pappu R, Kauder SE, Toy K, Ha C, Modrusan Z, Wu LC, Collard HR, Wolters PJ, Egen JG, Arron JR. PMID: 24879793.
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PubMed Mentions:
33 Fields:
Translation:
HumansCellsCTClinical Trials
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Predicting survival across chronic interstitial lung disease: the ILD-GAP model. Chest. 2014 Apr; 145(4):723-728.
Ryerson CJ, Vittinghoff E, Ley B, Lee JS, Mooney JJ, Jones KD, Elicker BM, Wolters PJ, Koth LL, King TE, Collard HR. PMID: 24114524.
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PubMed Mentions:
178 Fields:
Translation:
Humans
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Serum IgE clearance is facilitated by human FcεRI internalization. J Clin Invest. 2014 Mar; 124(3):1187-98.
Greer AM, Wu N, Putnam AL, Woodruff PG, Wolters P, Kinet JP, Shin JS. PMID: 24569373; PMCID: PMC3938266.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Increased susceptibility to Klebsiella pneumonia and mortality in GSNOR-deficient mice. Biochem Biophys Res Commun. 2013 Dec 06; 442(1-2):122-6.
Tang CH, Seeley EJ, Huang X, Wolters PJ, Liu L. PMID: 24239886; PMCID: PMC3885541.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease. Sci Transl Med. 2013 Oct 09; 5(206):206ra139.
Shum AK, Alimohammadi M, Tan CL, Cheng MH, Metzger TC, Law CS, Lwin W, Perheentupa J, Bour-Jordan H, Carel JC, Husebye ES, De Luca F, Janson C, Sargur R, Dubois N, Kajosaari M, Wolters PJ, Chapman HA, Kämpe O, Anderson MS. PMID: 24107778; PMCID: PMC3882146.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Pathogenesis of idiopathic pulmonary fibrosis. Annu Rev Pathol. 2014; 9:157-79.
Wolters PJ, Collard HR, Jones KD. PMID: 24050627; PMCID: PMC4116429.
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PubMed Mentions:
374 Fields:
Translation:
HumansCells
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Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet. 2013 Jun; 45(6):613-20.
Fingerlin TE, Murphy E, Zhang W, Peljto AL, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch D, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Cogan JD, Mason WR, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Smith K, McKean D, Pedersen BS, Talbert J, Kidd RN, Markin CR, Beckman KB, Lathrop M, Schwarz MI, Schwartz DA. PMID: 23583980; PMCID: PMC3677861.
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PubMed Mentions:
411 Fields:
Translation:
HumansCells
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Noradrenergic neurons regulate monocyte trafficking and mortality during gram-negative peritonitis in mice. J Immunol. 2013 May 01; 190(9):4717-24.
Seeley EJ, Barry SS, Narala S, Matthay MA, Wolters PJ. PMID: 23543756; PMCID: PMC3973442.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Prevalence and prognosis of unclassifiable interstitial lung disease. Eur Respir J. 2013 Sep; 42(3):750-7.
Ryerson CJ, Urbania TH, Richeldi L, Mooney JJ, Lee JS, Jones KD, Elicker BM, Koth LL, King TE, Wolters PJ, Collard HR. PMID: 23222877.
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PubMed Mentions:
95 Fields:
Translation:
Humans
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Prevalence and clinical significance of circulating autoantibodies in idiopathic pulmonary fibrosis. Respir Med. 2013 Feb; 107(2):249-55.
Lee JS, Kim EJ, Lynch KL, Elicker B, Ryerson CJ, Katsumoto TR, Shum AK, Wolters PJ, Cerri S, Richeldi L, Jones KD, King TE, Collard HR. PMID: 23186614; PMCID: PMC3543473.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis. Respir Res. 2012 Nov 20; 13:105.
Cha SI, Ryerson CJ, Lee JS, Kukreja J, Barry SS, Jones KD, Elicker BM, Kim DS, Papa FR, Collard HR, Wolters PJ. PMID: 23167970; PMCID: PMC3547729.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16354-9.
Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan YN, Jan LY, Rock JR. PMID: 22988107; PMCID: PMC3479591.
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PubMed Mentions:
180 Fields:
Translation:
HumansAnimalsCells
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Integrin α9β1 in airway smooth muscle suppresses exaggerated airway narrowing. J Clin Invest. 2012 Aug; 122(8):2916-27.
Chen C, Kudo M, Rutaganira F, Takano H, Lee C, Atakilit A, Robinett KS, Uede T, Wolters PJ, Shokat KM, Huang X, Sheppard D. PMID: 22772469; PMCID: PMC3448403.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Inflection points in sepsis biology: from local defense to systemic organ injury. Am J Physiol Lung Cell Mol Physiol. 2012 Sep; 303(5):L355-63.
Seeley EJ, Matthay MA, Wolters PJ. PMID: 22707617; PMCID: PMC3468422.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Noradrenergic neurons regulate the egress and trafficking of splenic monocytes and influence mortality during Gram-negative infection in mice. Critical Care. 2012 Jun 1; 16(Suppl 3):p71.
Seeley SE, Barry BS, Matthay MM, Wolters WP. .
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Relative versus absolute change in forced vital capacity in idiopathic pulmonary fibrosis. Thorax. 2012 May; 67(5):407-11.
Richeldi L, Ryerson CJ, Lee JS, Wolters PJ, Koth LL, Ley B, Elicker BM, Jones KD, King TE, Ryu JH, Collard HR. PMID: 22426899.
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PubMed Mentions:
67 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
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Bronchoalveolar lavage pepsin in acute exacerbation of idiopathic pulmonary fibrosis. Eur Respir J. 2012 Feb; 39(2):352-8.
Lee JS, Song JW, Wolters PJ, Elicker BM, King TE, Kim DS, Collard HR. PMID: 22183478; PMCID: PMC5529033.
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PubMed Mentions:
75 Fields:
Translation:
Humans
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Parasitic infection improves survival from septic peritonitis by enhancing mast cell responses to bacteria in mice. PLoS One. 2011; 6(11):e27564.
Sutherland RE, Xu X, Kim SS, Seeley EJ, Caughey GH, Wolters PJ. PMID: 22110673; PMCID: PMC3217977.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Interleukin-1beta induces increased transcriptional activation of the transforming growth factor-beta-activating integrin subunit beta8 through altering chromatin architecture. J Biol Chem. 2011 Oct 21; 286(42):36864-74.
Markovics JA, Araya J, Cambier S, Somanath S, Gline S, Jablons D, Hill A, Wolters PJ, Nishimura SL. PMID: 21878622; PMCID: PMC3196125.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2011 Dec 15; 184(12):1390-4.
Lee JS, Ryu JH, Elicker BM, Lydell CP, Jones KD, Wolters PJ, King TE, Collard HR. PMID: 21700909; PMCID: PMC3262030.
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PubMed Mentions:
133 Fields:
Translation:
Humans
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In search of the fibrotic epithelial cell: opportunities for a collaborative network. Thorax. 2012 Feb; 67(2):179-82.
Jenkins G, Blanchard A, Borok Z, Bradding P, Ehrhardt C, Fisher A, Hirani N, Johnson S, Königshoff M, Maher TM, Millar A, Parfrey H, Scotton C, Tetley T, Thickett D, Wolters P, ECIPF workshop. PMID: 21680569.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice. J Leukoc Biol. 2011 Sep; 90(3):591-7.
Seeley EJ, Sutherland RE, Kim SS, Wolters PJ. PMID: 21653231; PMCID: PMC3157900.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. J Clin Invest. 2011 Jul; 121(7):2863-75.
Kitamura H, Cambier S, Somanath S, Barker T, Minagawa S, Markovics J, Goodsell A, Publicover J, Reichardt L, Jablons D, Wolters P, Hill A, Marks JD, Lou J, Pittet JF, Gauldie J, Baron JL, Nishimura SL. PMID: 21646718; PMCID: PMC3223836.
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PubMed Mentions:
99 Fields:
Translation:
HumansAnimalsCells
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Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2011 Jul; 301(1):L71-8.
Marmai C, Sutherland RE, Kim KK, Dolganov GM, Fang X, Kim SS, Jiang S, Golden JA, Hoopes CW, Matthay MA, Chapman HA, Wolters PJ. PMID: 21498628; PMCID: PMC3129898.
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PubMed Mentions:
79 Fields:
Translation:
HumansAnimalsCells
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Viral infection in acute exacerbation of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2011 Jun 15; 183(12):1698-702.
Wootton SC, Kim DS, Kondoh Y, Chen E, Lee JS, Song JW, Huh JW, Taniguchi H, Chiu C, Boushey H, Lancaster LH, Wolters PJ, DeRisi J, Ganem D, Collard HR. PMID: 21471095; PMCID: PMC3136996.
View in:
PubMed Mentions:
123 Fields:
Translation:
HumansCells
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Transcription of the transforming growth factor beta activating integrin beta8 subunit is regulated by SP3, AP-1, and the p38 pathway. J Biol Chem. 2010 Aug 06; 285(32):24695-706.
Markovics JA, Araya J, Cambier S, Jablons D, Hill A, Wolters PJ, Nishimura SL. PMID: 20519498; PMCID: PMC2915706.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2010 Jul; 299(1):L3-7.
Collard HR, Calfee CS, Wolters PJ, Song JW, Hong SB, Brady S, Ishizaka A, Jones KD, King TE, Matthay MA, Kim DS. PMID: 20418386; PMCID: PMC2904092.
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PubMed Mentions:
85 Fields:
Translation:
Humans
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Undifferentiated connective tissue disease-associated interstitial lung disease: changes in lung function. Lung. 2010 Apr; 188(2):143-9.
Kinder BW, Shariat C, Collard HR, Koth LL, Wolters PJ, Golden JA, Panos RJ, King TE. PMID: 20069430; PMCID: PMC2837880.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages. J Clin Invest. 2009 Dec; 119(12):3713-22.
Atabai K, Jame S, Azhar N, Kuo A, Lam M, McKleroy W, Dehart G, Rahman S, Xia DD, Melton AC, Wolters P, Emson CL, Turner SM, Werb Z, Sheppard D. PMID: 19884654; PMCID: PMC2786804.
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119 Fields:
Translation:
AnimalsCells
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Could N-acetylcysteine slow progression of idiopathic pulmonary fibrosis by inhibiting EMT? Am J Physiol Lung Cell Mol Physiol. 2009 Nov; 297(5):L803-4.
Wolters PJ. PMID: 19700642.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med. 2009 Aug; 15(8):940-5.
Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP. PMID: 19633655; PMCID: PMC2736875.
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335 Fields:
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HumansAnimalsCells
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Neutrophil-derived IL-6 limits alveolar barrier disruption in experimental ventilator-induced lung injury. J Immunol. 2009 Jun 15; 182(12):8056-62.
Wolters PJ, Wray C, Sutherland RE, Kim SS, Koff J, Mao Y, Frank JA. PMID: 19494331; PMCID: PMC2737530.
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35 Fields:
Translation:
AnimalsCells
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Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis. J Clin Invest. 2009 Jan; 119(1):213-24.
Kim KK, Wei Y, Szekeres C, Kugler MC, Wolters PJ, Hill ML, Frank JA, Brumwell AN, Wheeler SE, Kreidberg JA, Chapman HA. PMID: 19104148; PMCID: PMC2613463.
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228 Fields:
Translation:
HumansAnimalsCells
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Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killing. J Immunol. 2008 Oct 15; 181(8):5598-605.
Sutherland RE, Olsen JS, McKinstry A, Villalta SA, Wolters PJ. PMID: 18832718; PMCID: PMC2610024.
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79 Fields:
Translation:
AnimalsCells
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Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest. 2007 Nov; 117(11):3359-68.
Sun J, Sukhova GK, Yang M, Wolters PJ, MacFarlane LA, Libby P, Sun C, Zhang Y, Liu J, Ennis TL, Knispel R, Xiong W, Thompson RW, Baxter BT, Shi GP. PMID: 17932568; PMCID: PMC2000808.
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PubMed Mentions:
121 Fields:
Translation:
HumansAnimalsCells
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Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients. J Clin Invest. 2007 Nov; 117(11):3551-62.
Araya J, Cambier S, Markovics JA, Wolters P, Jablons D, Hill A, Finkbeiner W, Jones K, Broaddus VC, Sheppard D, Barzcak A, Xiao Y, Erle DJ, Nishimura SL. PMID: 17965775; PMCID: PMC2040320.
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122 Fields:
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HumansAnimalsCells
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Use of mycophenolate mofetil to treat scleroderma-associated interstitial lung disease. Respir Med. 2008 Jan; 102(1):150-5.
Zamora AC, Wolters PJ, Collard HR, Connolly MK, Elicker BM, Webb WR, King TE, Golden JA. PMID: 17822892.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Relationships between early inflammatory response to bleomycin and sensitivity to lung fibrosis: a role for dipeptidyl-peptidase I and tissue inhibitor of metalloproteinase-3? Am J Respir Crit Care Med. 2007 Dec 01; 176(11):1098-107.
Pottier N, Chupin C, Defamie V, Cardinaud B, Sutherland R, Rios G, Gauthier F, Wolters PJ, Berthiaume Y, Barbry P, Mari B. PMID: 17673693.
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8 Fields:
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AnimalsCells
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PubMed Mentions:
100 Fields:
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Humans
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Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nat Med. 2007 Jun; 13(6):719-24.
Sun J, Sukhova GK, Wolters PJ, Yang M, Kitamoto S, Libby P, MacFarlane LA, Mallen-St Clair J, Shi GP. PMID: 17546038.
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PubMed Mentions:
163 Fields:
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HumansAnimalsCells
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Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis. Gastroenterology. 2007 Jun; 132(7):2422-37.
Cottrell GS, Amadesi S, Pikios S, Camerer E, Willardsen JA, Murphy BR, Caughey GH, Wolters PJ, Coughlin SR, Peterson A, Knecht W, Pothoulakis C, Bunnett NW, Grady EF. PMID: 17570216; PMCID: PMC2366898.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Clinical problem-solving. Anchors away. N Engl J Med. 2007 Feb 01; 356(5):504-9.
Calfee CS, Shah SJ, Wolters PJ, Saint S, King TE. PMID: 17267911.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Neutrophil histamine contributes to inflammation in mycoplasma pneumonia. J Exp Med. 2006 Dec 25; 203(13):2907-17.
Xu X, Zhang D, Zhang H, Wolters PJ, Killeen NP, Sullivan BM, Locksley RM, Lowell CA, Caughey GH. PMID: 17158962; PMCID: PMC2118183.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Cutting edge: Deficiency of macrophage migration inhibitory factor impairs murine airway allergic responses. J Immunol. 2006 Nov 01; 177(9):5779-84.
Wang B, Huang X, Wolters PJ, Sun J, Kitamoto S, Yang M, Riese R, Leng L, Chapman HA, Finn PW, David JR, Bucala R, Shi GP. PMID: 17056501.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci U S A. 2006 Aug 29; 103(35):13180-5.
Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. PMID: 16924102; PMCID: PMC1551904.
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PubMed Mentions:
617 Fields:
Translation:
HumansAnimalsCells
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Cathepsins L and S are not required for activation of dipeptidyl peptidase I (cathepsin C) in mice. Biol Chem. 2006 Aug; 387(8):1143-6.
Mallen-St Clair J, Shi GP, Sutherland RE, Chapman HA, Caughey GH, Wolters PJ. PMID: 16895486; PMCID: PMC2271110.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Neurofibromatosis-associated lung disease: a case series and literature review. Eur Respir J. 2007 Jan; 29(1):210-4.
Zamora AC, Collard HR, Wolters PJ, Webb WR, King TE. PMID: 16870664.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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Mast cells protect mice from Mycoplasma pneumonia. Am J Respir Crit Care Med. 2006 Jan 15; 173(2):219-25.
Xu X, Zhang D, Lyubynska N, Wolters PJ, Killeen NP, Baluk P, McDonald DM, Hawgood S, Caughey GH. PMID: 16210667; PMCID: PMC2662990.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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c-Kit immunophenotyping and metalloproteinase expression profiles of mast cells in interstitial lung diseases. J Pathol. 2005 Jul; 206(3):279-90.
Edwards ST, Cruz AC, Donnelly S, Dazin PF, Schulman ES, Jones KD, Wolters PJ, Hoopes C, Dolganov GM, Fang KC. PMID: 15887294.
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22 Fields:
Translation:
HumansCells
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Tissue-selective mast cell reconstitution and differential lung gene expression in mast cell-deficient Kit(W-sh)/Kit(W-sh) sash mice. Clin Exp Allergy. 2005 Jan; 35(1):82-8.
Wolters PJ, Mallen-St Clair J, Lewis CC, Villalta SA, Baluk P, Erle DJ, Caughey GH. PMID: 15649271; PMCID: PMC2271075.
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PubMed Mentions:
87 Fields:
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AnimalsCells
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Mast cell dipeptidyl peptidase I mediates survival from sepsis. J Clin Invest. 2004 Feb; 113(4):628-34.
Mallen-St Clair J, Pham CT, Villalta SA, Caughey GH, Wolters PJ. PMID: 14966572; PMCID: PMC338261.
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62 Fields:
Translation:
AnimalsCells
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Mast cell cathepsins C and S control levels of carboxypeptidase A and the chymase, mouse mast cell protease 5. Biol Chem. 2003 Oct-Nov; 384(10-11):1527-31.
Henningsson F, Wolters P, Chapman HA, Caughey GH, Pejler G. PMID: 14669996.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Structure and activity of human pancreasin, a novel tryptic serine peptidase expressed primarily by the pancreas. J Biol Chem. 2003 Jan 31; 278(5):3363-71.
Bhagwandin VJ, Hau LW, Mallen-St Clair J, Wolters PJ, Caughey GH. PMID: 12441343.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Lys40 but not Arg143 influences selectivity of angiotensin conversion by human alpha-chymase. Biochim Biophys Acta. 2002 Apr 29; 1596(2):346-56.
Muilenburg DJ, Raymond WW, Wolters PJ, Caughey GH. PMID: 12007614.
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9 Fields:
Translation:
HumansAnimalsCells
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Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice. J Biol Chem. 2001 May 25; 276(21):18551-6.
Wolters PJ, Pham CT, Muilenburg DJ, Ley TJ, Caughey GH. PMID: 11279033.
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70 Fields:
Translation:
AnimalsCells
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Importance of lysosomal cysteine proteases in lung disease. Respir Res. 2000; 1(3):170-7.
Wolters PJ, Chapman HA. PMID: 11667982; PMCID: PMC59556.
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32 Fields:
Translation:
HumansAnimalsCells
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Angiotensin II generation by mast cell alpha- and beta-chymases. Biochim Biophys Acta. 2000 Jul 14; 1480(1-2):245-57.
Caughey GH, Raymond WW, Wolters PJ. PMID: 10899625.
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75 Fields:
Translation:
HumansAnimalsCells
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Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families. J Immunol. 2000 Jun 15; 164(12):6566-75.
Caughey GH, Raymond WW, Blount JL, Hau LW, Pallaoro M, Wolters PJ, Verghese GM. PMID: 10843716.
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36 Fields:
Translation:
HumansAnimalsCells
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Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways. Am J Respir Cell Mol Biol. 2000 Feb; 22(2):183-90.
Wolters PJ, Laig-Webster M, Caughey GH. PMID: 10657939.
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25 Fields:
Translation:
AnimalsCells
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Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta. J Immunol. 1999 May 01; 162(9):5528-35.
Fang KC, Wolters PJ, Steinhoff M, Bidgol A, Blount JL, Caughey GH. PMID: 10228034.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Regulated expression, processing, and secretion of dog mast cell dipeptidyl peptidase I. J Biol Chem. 1998 Jun 19; 273(25):15514-20.
Wolters PJ, Raymond WW, Blount JL, Caughey GH. PMID: 9624139.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Polymer length of teichuronic acid released from cell walls of Micrococcus luteus. J Bacteriol. 1990 Sep; 172(9):5154-9.
Wolters PJ, Hildebrandt KM, Dickie JP, Anderson JS. PMID: 2394683; PMCID: PMC213175.
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PubMed Mentions:
15 Fields:
Translation:
Cells
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Evidence for chloride secretion in the intestine of the winter flounder. Am J Physiol. 1990 Feb; 258(2 Pt 1):C243-7.
O'Grady SM, Wolters PJ. PMID: 2305867.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Cardiac antisecretory peptide inhibits intestinal chloride secretion. Am J Physiol. 1989 Oct; 257(4 Pt 1):C775-80.
O'Grady SM, Wolters PJ. PMID: 2801925.
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Animals
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Regulation of ion transport in porcine gallbladder: effects of VIP and norepinephrine. Am J Physiol. 1989 Jul; 257(1 Pt 1):C52-7.
O'Grady SM, Wolters PJ, Hildebrand K, Brown DR. PMID: 2546435.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Sodium and chloride transport across the isolated porcine gallbladder. Am J Physiol. 1989 Jul; 257(1 Pt 1):C45-51.
O'Grady SM, Wolters PJ. PMID: 2750890.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells