William Temple, MD

Title(s)Clinical Fellow, Pediatrics
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone--
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    Collapse Biography 
    Collapse Education and Training
    UC Los Angeles, Los Angeles, CAB.S.06/2011Microbiology, Immunology, and Molecular Genetics
    UC San Francisco, San Francisco, CAM.D.05/2016Medicine
    UC San Francisco, San Francisco, CA06/2019Pediatrics Residency
    UC San Francisco, San Francisco, CA07/2022Clinical Fellow, Pediatric Hematology & Oncology
    UC San Francisco, San Francisco, CA07/2024Advanced Fellow, Pediatric Blood & Marrow Transplantation and Immunotherapy

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    CD72 nanoCARs for treatment of relapsed/refractory B cell malignancies
    American Society of Hematology - Research Training Award for Fellows Jul 1, 2022 - Jun 30, 2022
    CD72 Nanobody-based CAR-T cells for relapsed/refractory B cell malignancies
    Chan Zuckerberg Biohub Physician-Scientist Fellowship Program Jul 1, 2020 - Jun 30, 2023
    CD72 Nanobody-based CAR-T cells for relapsed/refractory B cell malignancies
    NIH T32 - Research Training in Childhood Cancer Jul 1, 2020 - Jun 30, 2022
    Role: Trainee on the grant

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Blood. Humanized Nanobody Anti-CD72 CAR-T Cells Efficiently Eliminate B-Cell Malignancies Via Improved Affinity for CD72 but Induce Persistent Antigen Downregulation In Vivo. 2022. William C Temple, Gianina Wicaksono, Akul Naik, Adila Izgutdina, Matthew A Nix, Elizabeth Young, Paul Phojanakong, Juan Antonio Camara Serrano, Veronica Steri, Fernando Salangsang, Arun P Wiita. View Publication.
    2. Blood. Structural Surfaceomics Reveals an AML-Specific Conformation of Integrin-β2 As an Immunotherapeutic Target. 2022. Kamal Mandal, Gianina Wicaksono, Clinton Yu, Jarrett J Adams, Michael R Hoopmann, William C Temple, Bonell Patino Escobar, Maryna Gorelik, Christian Ihling, Matthew A Nix, Akul Naik, Emilio Ramos, Corynn Kasap, Veronica Steri, Juan Antonio Camara Serrano, Fernando Salangsang, Paul Phojanakong, Melanie McMillan, Victor Gavallos, Andrew D Leavitt, Andrea Sinz, Benjamin J. Huang, Elliot Stieglitz, Catherine Smith, Robert L Moritz, Sachdeva S Sidhu, Lan Huang, Arun P Wiita. View Publication.
    3. Leukemia Research. CD72 nanobody CAR-T cells have potent antitumor efficacy in B cell malignancies. 2022; 121:S8. W. Temple, M. Nix, G. Wicaksono, D. Wang, P. Phojanakong, V. Steri, B. Hann, M. Hermiston, A. Wiita. View Publication.
    4. Incorporating Radiomics into Machine Learning Models to Predict Outcomes of Neuroblastoma. J Digit Imaging. 2022 06; 35(3):605-612. Liu G, Poon M, Zapala MA, Temple WC, Vo KT, Matthay KK, Mitra D, Seo Y. PMID: 35237892; PMCID: PMC9156639.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Blood. CD72 Nanobody-Based CAR-T Cells Have Potent Anti-Tumor Efficacy in B Cell Malignancies. 2021; (138 (Suppl):1717. Matthew A Nix, William C Temple, William Karlon, Donghui Wang, Paul Phojanakong, Veronica Steri, Byron Hann, Arun P Wiita. View Publication.
    6. Association of image-defined risk factors with clinical features, histopathology, and outcomes in neuroblastoma. Cancer Med. 2021 04; 10(7):2232-2241. Temple WC, Vo KT, Matthay KK, Balliu B, Coleman C, Michlitsch J, Phelps A, Behr S, Zapala MA. PMID: 33314708; PMCID: PMC7982630.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring. Front Genet. 2018; 9:642. Martin LJ, Meng Q, Blencowe M, Lagarrigue S, Xiao S, Pan C, Wier J, Temple WC, Devaskar SU, Lusis AJ, Yang X. PMID: 30619467; PMCID: PMC6297185.
      View in: PubMed   Mentions: 5  
    8. Erratum to: Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's Oncology Group. Eur J Nucl Med Mol Imaging. 2016 Jul; 43(7):1396. Temple W, Mendelsohn L, Kim GE, Nekritz E, Gustafson WC, Lin L, Giacomini K, Naranjo A, Van Ryn C, Parisi MT, Shulkin BL, Yanik GA, Kreissman SG, Hogarty M, Matthay KK, DuBois SG. PMID: 27044383.
      View in: PubMed   Mentions:    Fields:    
    9. Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's Oncology Group. Eur J Nucl Med Mol Imaging. 2016 Mar; 43(3):474-481. Temple W, Mendelsohn L, Kim GE, Nekritz E, Gustafson WC, Lin L, Giacomini K, Naranjo A, Van Ryn C, Yanik GA, Kreissman SG, Hogarty M, Matthay KK, DuBois SG. PMID: 26338179; PMCID: PMC4733400.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells