Loading...

Michelle Hermiston, MD, PhD

Title(s)Associate Professor, Pediatrics
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone415-476-3831
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency Pediatrics
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training

    Collapse Research 
    Collapse Research Activities and Funding
    Improving risk allocation and developing novel therapies for children with T-ALL
    NIH/NCI R01CA193776May 4, 2015 - Apr 30, 2020
    Role: Co-Principal Investigator
    Interplay of Innate and Adaptive Immunity in Lupus Pathogenesis
    NIH/NIAID R01AI089831Jun 1, 2010 - May 31, 2015
    Role: Principal Investigator
    Role of CD45 in Hematopoiesis and Lymphomagenesis
    NIH/NCI K08CA098418Jul 11, 2003 - Jun 30, 2007
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites
    Collapse Student Projects

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Successful Outcomes of Newly Diagnosed T Lymphoblastic Lymphoma: Results From Children's Oncology Group AALL0434. J Clin Oncol. 2020 Jun 17; JCO2000531. Hayashi RJ, Winter SS, Dunsmore KP, Devidas M, Chen Z, Wood BL, Hermiston ML, Teachey DT, Perkins SL, Miles RR, Raetz EA, Loh ML, Winick NJ, Carroll WL, Hunger SP, Lim MS, Gross TG, Bollard CM. PMID: 32552472.
      View in: PubMed   Mentions:    Fields:    
    2. JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation. Blood. 2020 Jun 12. Meyer L, Verbist KC, Albeituni S, Scull BP, Bassett R, Stroh AN, Tillman H, Allen CE, Hermiston M, Nichols KE. PMID: 32530039.
      View in: PubMed   Mentions:    Fields:    
    3. Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes. J Clin Invest. 2020 Feb 03; 130(2):863-876. Meyer LK, Huang BJ, Delgado-Martin C, Roy RP, Hechmer A, Wandler AM, Vincent TL, Fortina P, Olshen AB, Wood BL, Horton TM, Shannon KM, Teachey DT, Hermiston ML. PMID: 31687977.
      View in: PubMed   Mentions:    Fields:    
    4. Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study. Clin Cancer Res. 2020 May 15; 26(10):2297-2307. Burke MJ, Kostadinov R, Sposto R, Gore L, Kelley SM, Rabik C, Trepel JB, Lee MJ, Yuno A, Lee S, Bhojwani D, Jeha S, Chang BH, Sulis ML, Hermiston ML, Gaynon P, Huynh V, Verma A, Gardner R, Heym KM, Dennis RM, Ziegler DS, Laetsch TW, Oesterheld JE, Dubois SG, Pollard JA, Glade-Bender J, Cooper TM, Kaplan JA, Farooqi MS, Yoo B, Guest E, Wayne AS, Brown PA. PMID: 31969338.
      View in: PubMed   Mentions:    Fields:    
    5. The Combination of Dexamethasone and Ruxolitinib Synergistically Attenuates Disease Manifestations in a Preclinical Model of Hemophagocytic Lymphohistiocytosis. Blood. 2019 Nov 13; 134(Supplement_1):81-81. Lauren K. Meyer, Katherine Verbist, Sabrin Albeituni, Rachel Bassett, Michelle L. Hermiston, Kim E. Nichols. .
      View in: Publisher Site   Mentions:
    6. Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia. Blood. 2019 Nov 13; 134(Supplement_1):805-805. Lauren K. Meyer, Cristina Delgado-Martin, Phillip P. Sharp, Dustin McMinn, Christopher J. Kirk, Jack Taunton, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    7. Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis. Blood. 2019 Nov 13; 134(Supplement_1):3343-3343. Aleksandra S. Dain, Michelle L. Hermiston, Kristin A. Shimano, Sandhya Kharbanda, Alexis Melton, Jasmeen Dara, James N Huang, Christopher C. Dvorak. .
      View in: Publisher Site   Mentions:
    8. Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: Recommendations from the North American Consortium for Histiocytosis (NACHO). Pediatr Blood Cancer. 2019 11; 66(11):e27929. Jordan MB, Allen CE, Greenberg J, Henry M, Hermiston ML, Kumar A, Hines M, Eckstein O, Ladisch S, Nichols KE, Rodriguez-Galindo C, Wistinghausen B, McClain KL. PMID: 31339233.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. CRLF2 rearrangement in Ph-like acute lymphoblastic leukemia predicts relative glucocorticoid resistance that is overcome with MEK or Akt inhibition. PLoS One. 2019; 14(7):e0220026. Meyer LK, Delgado-Martin C, Maude SL, Shannon KM, Teachey DT, Hermiston ML. PMID: 31318944.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Calming the storm in HLH. Blood. 2019 07 11; 134(2):103-104. Zinter MS, Hermiston ML. PMID: 31296541.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    11. Gene expression signature associated with in vitro dexamethasone resistance and post-induction minimal residual disease in pediatric T-cell acute lymphoblastic leukemia. Journal of Clinical Oncology. 2019 May 20; 37(15_suppl):10033-10033. Lauren K. Meyer, Cristina Delgado-Martin, Ritu Roy, Benjamin J. Huang, Tiffaney Vincent, Adam Olshen, Brent L. Wood, Yu Liu, Jinghui Zhang, Charles Grenfell Mullighan, Terzah M. Horton, Mignon L. Loh, Meenakshi Devidas, Elizabeth A. Raetz, Robert J. Hayashi, Stuart Winter, Kimberly P. Dunsmore, Stephen Hunger, David T. Teachey, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    12. Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities. Br J Haematol. 2019 06; 185(6):1158-1170. Burkhardt B, Hermiston ML. PMID: 30809797.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. The bone marrow microenvironment as a mediator of chemoresistance in acute lymphoblastic leukemia. Cancer Drug Resistance. 2019 Jan 1. Lauren K Meyer, Michelle L Hermiston. .
      View in: Publisher Site   Mentions:
    14. The epigenome in pediatric acute lymphoblastic leukemia: drug resistance and therapeutic opportunities. Cancer Drug Resistance. 2019 Jan 1. Lauren K Meyer, Michelle L Hermiston. .
      View in: Publisher Site   Mentions:
    15. Mechanisms of Glucocorticoid Response and Resistance in Lymphoid Malignancies. . 2019 Jan 1; 21:1-26. Lauren K. Meyer, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    16. Children's Oncology Group (COG) AALL0434: Successful Disease Control without Cranial Radiation in Newly Diagnosed T Lymphoblastic Lymphoma (T-LL). Blood. 2018 Nov 29; 132(Supplement 1):1000-1000. Robert James Hayashi, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Brent Wood, Michelle L. Hermiston, David T Teachey, Sherrie L. Perkins, Rodney R. Miles, Elizabeth A. Raetz, Mignon L. Loh, Naomi Winick, William L. Carroll, Stephen P. Hunger, Megan S. Lim, Catherine M. Bollard, Thomas G. Gross. .
      View in: Publisher Site   Mentions:
    17. Glucocorticoids Paradoxically Induce Intrinsic Steroid Resistance through a STAT5-Mediated Survival Mechanism in T-Cell Acute Lymphoblastic Leukemia. Blood. 2018 Nov 29; 132(Supplement 1):913-913. Lauren K. Meyer, Benjamin Huang, Ritu Roy, Aaron Hechmer, Anica Wandler, Cristina Delgado-Martin, Adam B. Olshen, Terzah M. Horton, David T Teachey, Kevin M. Shannon, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    18. Ibrutinib significantly inhibited Bruton's tyrosine kinase (BTK) phosphorylation,in-vitro proliferation and enhanced overall survival in a preclinical Burkitt lymphoma (BL) model. Oncoimmunology. 2019; 8(1):e1512455. Chu Y, Lee S, Shah T, Yin C, Barth M, Miles RR, Ayello J, Morris E, Harrison L, Van de Ven C, Galardy P, Goldman SC, Lim MS, Hermiston M, McAllister-Lucas LM, Giulino-Roth L, Perkins SL, Cairo MS. PMID: 30546948.
      View in: PubMed   Mentions:
    19. Age-Related Impaired Efficacy of Bone Marrow Cell Therapy for Myocardial Infarction Reflects a Decrease in B Lymphocytes. Mol Ther. 2018 07 05; 26(7):1685-1693. An S, Wang X, Ruck MA, Rodriguez HJ, Kostyushev DS, Varga M, Luu E, Derakhshandeh R, Suchkov SV, Kogan SC, Hermiston ML, Springer ML. PMID: 29914756.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    20. High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL. SLAS Discov. 2018 08; 23(7):732-741. Perez DR, Nickl CK, Waller A, Delgado-Martin C, Woods T, Sharma ND, Hermiston ML, Loh ML, Hunger SP, Winter SS, Chigaev A, Edwards B, Sklar LA, Matlawska-Wasowska K. PMID: 29746793.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    21. Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study. Leukemia. 2018 11; 32(11):2316-2325. Sun W, Malvar J, Sposto R, Verma A, Wilkes JJ, Dennis R, Heym K, Laetsch TW, Widener M, Rheingold SR, Oesterheld J, Hijiya N, Sulis ML, Huynh V, Place AE, Bittencourt H, Hutchinson R, Messinger Y, Chang B, Matloub Y, Ziegler DS, Gardner R, Cooper T, Ceppi F, Hermiston M, Dalla-Pozza L, Schultz KR, Gaynon P, Wayne AS, Whitlock JA. PMID: 29728694.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia. Blood. 2018 03 01; 131(9):995-999. Bride KL, Vincent TL, Im SY, Aplenc R, Barrett DM, Carroll WL, Carson R, Dai Y, Devidas M, Dunsmore KP, Fuller T, Glisovic-Aplenc T, Horton TM, Hunger SP, Loh ML, Maude SL, Raetz EA, Winter SS, Grupp SA, Hermiston ML, Wood BL, Teachey DT. PMID: 29305553.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    23. Evaluation and treatment of Langerhans cell histiocytosis patients with central nervous system abnormalities: Current views and new vistas. Pediatr Blood Cancer. 2018 Jan; 65(1). Yeh EA, Greenberg J, Abla O, Longoni G, Diamond E, Hermiston M, Tran B, Rodriguez-Galindo C, Allen CE, McClain KL. PMID: 28944988.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases. Proc Natl Acad Sci U S A. 2017 06 13; 114(24):E4782-E4791. McNally JP, Millen SH, Chaturvedi V, Lakes N, Terrell CE, Elfers EE, Carroll KR, Hogan SP, Andreassen PR, Kanter J, Allen CE, Henry MM, Greenberg JN, Ladisch S, Hermiston ML, Joyce M, Hildeman DA, Katz JD, Jordan MB. PMID: 28533414.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    25. JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias. Leukemia. 2017 12; 31(12):2568-2576. Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML. PMID: 28484265.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    26. Mechanism of IL-10 Protective Effect in Development of Childhood B Cell Acute Lymphoblastic Leukemia. Blood. 2016 Dec 2; 128(22):4075-4075. Briana Fitch, Michelle L. Hermiston, Joseph L. Wiemels, Scott C. Kogan. .
      View in: Publisher Site   Mentions:
    27. Measurement of Phosphorylated ERK As a Prognostic and Predictive Marker for MEK Inhibition in Pediatric B-Lymphoblastic Leukemia: A Pilot Study. Blood. 2016 Dec 2; 128(22):1739-1739. Pillai Pallavi Madhusoodhan, Nikki Ann Evensen, Jason Saliba, Ashfiyah Chowdhury, Daniel Newman, Cristina Delgado-Martin, Teena Bhatla, Mignon L. Loh, Michelle L. Hermiston, William L. Carroll. .
      View in: Publisher Site   Mentions:
    28. Microrna (miR)-17-92 Contributes to Therapy Resistance in Burkitt Lymphoma Cells. Blood. 2016 Dec 2; 128(22):2944-2944. Rodney R. Miles, Vladimir Rodic, Matthew J. Barth, Mitchell S. Cairo, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    29. JAK/STAT Pathway Inhibition Reverts IL7-Induced Glucocorticoid Resistance in a Subset of Human T-Cell Acute Lymphoblastic Leukemia. Blood. 2016 Dec 2; 128(22):3963-3963. Cristina Delgado-Martin, Kristin Shimano, Matthew S Zinter, Justin T. Wahlstrom, Geoffrey A. Smith, Jack Taunton, Stuart S. Winter, Justine E. Roderick, Michelle Kelliher, Terzah M. Horton, Brent L. Wood, David T Teachey, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    30. CRLF2 Rearrangement Status in Ph-like ALL Predicts Intrinsic Glucocorticoid Resistance In Vitro that is Reversible with Targeted MAPK and PI3K Pathway Inhibition. Blood. 2016 Dec 2; 128(22):910-910. Lauren K Meyer, Cristina Delgado-Martin, Shannon L Maude, David T Teachey, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    31. Targeting childhood, adolescent and young adult non-Hodgkin lymphoma: therapeutic horizons. Br J Haematol. 2016 05; 173(4):625-36. Galardy PJ, Bedekovics T, Hermiston ML. PMID: 27019108.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. Ibrutinib Alone and in Combination with Dexamethasone and Carfilzomib Significantly Inhibits Cell Proliferation in Primary Mediastinal B-Cell Lymphoma (PMBL): Ibrutinib May be a Future Targeted Agent in Combination Therapy in Patients with PMBL. Blood. 2015 Dec 3; 126(23):4852-4852. Sanghoon Lee, Changhong Yin, Janet Ayello, Erin Morris, Lauren Harrison, Carmella van de Ven, Matthew J. Barth, Rodney R. Miles, Paul J. Galardy, Stanton Goldman, Megan S Lim, Michelle L. Hermiston, Linda McAllister-Lucas, Lisa Giulino-Roth, Sherrie L. Perkins, Mitchell S. Cairo. .
      View in: Publisher Site   Mentions:
    33. Ibrutinib Significantly Prolonged Survival in a Human Burkitt Lymphoma (BL) Xenograft NSG Mouse Model: Ibrutinib May be a Potential Adjuvant Agent in the Treatment of BL. Blood. 2015 Dec 3; 126(23):5117-5117. Sanghoon Lee, Changhong Yin, Janet Ayello, Erin Morris, Timmy O'Connell, Lauren Harrison, Carmella van de Ven, Matthew J. Barth, Rodney R. Miles, Paul J. Galardy, Stanton Goldman, Megan S Lim, Michelle L. Hermiston, Linda McAllister-Lucas, Lisa Giulino-Roth, Sherrie L. Perkins, Mitchell S. Cairo. .
      View in: Publisher Site   Mentions:
    34. MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia. Blood. 2015 Nov 05; 126(19):2202-12. Jones CL, Gearheart CM, Fosmire S, Delgado-Martin C, Evensen NA, Bride K, Waanders AJ, Pais F, Wang J, Bhatla T, Bitterman DS, de Rijk SR, Bourgeois W, Dandekar S, Park E, Burleson TM, Madhusoodhan PP, Teachey DT, Raetz EA, Hermiston ML, Müschen M, Loh ML, Hunger SP, Zhang J, Garabedian MJ, Porter CC, Carroll WL. PMID: 26324703.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    35. Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production. J Immunol. 2015 Apr 15; 194(8):3675-86. Mills RE, Lam VC, Tan A, Cresalia N, Oksenberg N, Zikherman J, Anderson M, Weiss A, Hermiston ML. PMID: 25769918.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    36. Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia. Blood. 2015 Mar 12; 125(11):1759-67. Maude SL, Dolai S, Delgado-Martin C, Vincent T, Robbins A, Selvanathan A, Ryan T, Hall J, Wood AC, Tasian SK, Hunger SP, Loh ML, Mullighan CG, Wood BL, Hermiston ML, Grupp SA, Lock RB, Teachey DT. PMID: 25645356.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    37. The CXCR4/CXCL12 Axis Mediates Chemotaxis, Survival, and Chemoresistance in T-Cell Acute Lymphoblastic Leukemia. Blood. 2014 Dec 6; 124(21):3629-3629. Angela Liou, Cristina Delgado-Martin, David T. Teachey, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    38. MAPK Signaling Cascades Mediate Distinct Glucocorticoid Resistance Mechanisms in Pediatric B-Precursor ALL. Blood. 2014 Dec 6; 124(21):789-789. Courtney L Jones, Christy M Gearheart, Susan Fosmire, Cristina Delgado-Martin, Faye Pais, Jinhua Wang, Teena Bhatla, Danielle S Bitterman, Simone R de Rijk, Wallace Bourgeois, Smita C. Dandekar, Elizabeth A. Raetz, Michelle L. Hermiston, Michael J Garabedian, Christopher C. Porter, William L. Carroll. .
      View in: Publisher Site   Mentions:
    39. Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia. Br J Haematol. 2014 Oct; 167(1):87-99. Dandekar S, Romanos-Sirakis E, Pais F, Bhatla T, Jones C, Bourgeois W, Hunger SP, Raetz EA, Hermiston ML, Dasgupta R, Morrison DJ, Carroll WL. PMID: 24995804.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    40. A(nother) RAF mutation in LCH. Blood. 2014 May 15; 123(20):3063-5. Shannon K, Hermiston M. PMID: 24832939.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    41. Inhibition Of The Wnt Pathway Leads To Improved Chemosensitivity In Pediatric Acute Lymphoblastic Leukemia. Blood. 2013 Nov 15; 122(21):1428-1428. Smita C. Dandekar, Eleny Romanos-Sirakis, Faye Pais, Teena Bhatla, Courtney L Jones, Wallace Bourgeois, Stephen P. Hunger, Elizabeth A. Raetz, Michelle L. Hermiston, Ramanuj Dasgupta, Debra J. Morrison, William L. Carroll. .
      View in: Publisher Site   Mentions:
    42. Transcription Activator-Like Effector Nucleases (TALENs)-Mediated Deletion Of MIR17HG In Burkitt Lymphoma Cells Decreases mTOR Pathway Activity and Increases Chemosensitivity. Blood. 2013 Nov 15; 122(21):243-243. Faye Pais, Sanghoon Lee, Vladimir Rodic, Matthew J. Barth, Mitchell S. Cairo, Michelle L. Hermiston, Rodney R. Miles. .
      View in: Publisher Site   Mentions:
    43. Histone Deacetylase Inhibitors Enhance Cell Death In Burkitt Lymphoma Cells By Modulating Expression Of The WNT/ß-Catenin Pathway and Survivin. Blood. 2013 Nov 15; 122(21):1291-1291. Faye Pais, Matthew J. Barth, Rodney R. Miles, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    44. The structural wedge domain of the receptor-like tyrosine phosphatase CD45 enforces B cell tolerance by regulating substrate specificity. J Immunol. 2013 Mar 15; 190(6):2527-35. Zikherman J, Parameswaran R, Hermiston M, Weiss A. PMID: 23396948.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    45. Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations. Leukemia. 2013 Jul; 27(7):1570-3. Li M, Jones L, Gaillard C, Binnewies M, Ochoa R, Garcia E, Lam V, Wei G, Yang W, Lobe C, Hermiston M, Passegué E, Kogan SC. PMID: 23443342.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    46. The Order of Exposure to Cytotoxic Chemotherapy and the Proteasome Inhibitor Bortezomib Dictates the Extent of Reversal of Chemotherapy Resistance in T-ALL. Blood. 2012 Nov 16; 120(21):1355-1355. May Y. Szeto, Justin Wahlstrom, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    47. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 2012 Jan 11; 481(7380):157-63. Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG. PMID: 22237106.
      View in: PubMed   Mentions: 523     Fields:    Translation:HumansCells
    48. Aberrant MAPK and PI3K Signaling Contribute to Chemotherapy Resistance in T Cell Acute Lymphoblastic Leukemia by Altering the Balance of Apoptosis Mediators,. Blood. 2011 Nov 18; 118(21):3490-3490. Justin Wahlstrom, Kristin Ammon, Christopher Esquivel, Jason Law, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    49. Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project. Blood. 2011 Nov 18; 118(21):68-68. Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Susan L. Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch, Charles Lu, Shann-Ching Chen, Racquel Collins-Underwood, Jing Ma, Kathryn G. Roberts, Stanley Pounds, Lei Wei, Anatoly Ulyanov, Jared Becksfort, Pankaj Gupta, Robert Huether, Richard Kriwacki, Daniel McGoldrick, David Zhao, Daniel Alford, Stephen Espy, Kiran Chand Bobba, Guangchun Song, Deqing Pei, Cheng Cheng, Stefan Roberts, Michael Barbato, Dario Campana, Elaine Coustan-Smith, William E. Evans, Sheila A Shurtleff, Maria Kleppe, Jan Cools, Kristin Shimano, Michelle L. Hermiston, Sergei Doulatov, Kolja Eppert, Elisa Laurenti, Faiyaz Notta, John E Dick, Giuseppe Basso, Stephen P. Hunger, Mignon L Loh, Meenakshi Devidas, Brent L. Wood, Stuart S. Winter, Kimberly Dunsmore, Robert S. Fulton, Lucinda A. Fulton, Xin Hong, Christopher C. Harris, David J. Dooling, Kerri Ochoa, Kimberly J Johnson, John C Obenauer, Ching-Hon Pui, Susana C. Raimondi, Clayton W Naeve, Timothy J Ley, Elaine R Mardis, Richard K Wilson, James R Downing, Charles G Mullighan. .
      View in: Publisher Site   Mentions:
    50. Donor myocardial infarction impairs the therapeutic potential of bone marrow cells by an interleukin-1-mediated inflammatory response. Sci Transl Med. 2011 Sep 14; 3(100):100ra90. Wang X, Takagawa J, Lam VC, Haddad DJ, Tobler DL, Mok PY, Zhang Y, Clifford BT, Pinnamaneni K, Saini SA, Su R, Bartel MJ, Sievers RE, Carbone L, Kogan S, Yeghiazarians Y, Hermiston M, Springer ML. PMID: 21918107.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    51. Chapter 95 CD45. Handbook of Cell Signaling. 2010 Jan 1; 743-748. Michelle L. Hermiston, Vikas Gupta, Arthur Weiss. .
      View in: Publisher Site   Mentions:
    52. Distinct Signaling Profiles and Drug Responses Identify Subpopulations of Pediatric T-Cell Acute Lymphoblastic Leukemia and Lymphoma Patients. Blood. 2009 Nov 20; 114(22):1595-1595. Jason Law, Kristin Ammon, Matt Zinter, Jason Wen, Brian Cook, Jonathan M Irish, Michelle L. Hermiston. .
      View in: Publisher Site   Mentions:
    53. PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background. J Immunol. 2009 Apr 01; 182(7):4093-106. Zikherman J, Hermiston M, Steiner D, Hasegawa K, Chan A, Weiss A. PMID: 19299707.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    54. Requirement for CD45 in fine-tuning mast cell responses mediated by different ligand-receptor systems. Cell Signal. 2009 Aug; 21(8):1277-86. Grochowy G, Hermiston ML, Kuhny M, Weiss A, Huber M. PMID: 19332117.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    55. Oncogenic Kras initiates leukemia in hematopoietic stem cells. PLoS Biol. 2009 Mar 17; 7(3):e59. Sabnis AJ, Cheung LS, Dail M, Kang HC, Santaguida M, Hermiston ML, Passegué E, Shannon K, Braun BS. PMID: 19296721.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    56. CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells. Immunol Rev. 2009 Mar; 228(1):288-311. Hermiston ML, Zikherman J, Zhu JW. PMID: 19290935.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    57. Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):546-51. Hermiston ML, Zikherman J, Tan AL, Lam VC, Cresalia NM, Oksenberg N, Goren N, Brassat D, Oksenberg JR, Weiss A. PMID: 19129486.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    58. B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency. J Exp Med. 2008 Nov 24; 205(12):2755-61. Gupta VA, Hermiston ML, Cassafer G, Daikh DI, Weiss A. PMID: 19001138.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    59. Langerhans' Cell Histiocytosis. Clinical Endocrine Oncology. 2008 Apr 15; 325-330. Matthew F. Gorman, Michelle Hermiston, Katherine K. Matthay. .
      View in: Publisher Site   Mentions:
    60. A Point Mutation in the Juxtamembrane Wedge of CD45 Impacts Myeloid Development and Generates a Novel Model for Hemophagocytic Disorders in the Context of a MHC I-Restricted Transgene. Blood. 2007 Nov 16; 110(11):317-317. Michelle L. Hermiston, Fleur R. de Graaf, Art Weiss. .
      View in: Publisher Site   Mentions:
    61. The Phenotypic Consequences of an Activating Mutation in the Juxtamembrane Wedge of CD45 Is Sensitive to Genetic Modifiers. Blood. 2006 Nov 16; 108(11):1730-1730. Michelle L. Hermiston, Nicole M. Cresalia, Viola Lam, Allison L. Tan, Arthur Weiss. .
      View in: Publisher Site   Mentions:
    62. Epstein-Barr virus-associated B cell lymphoproliferative disease in a child with neonatal-onset multisystem inflammatory disease. Arthritis Rheum. 2006 Oct 15; 55(5):823-5. Modica R, Emery H, Lam W, Hermiston M, Grenert J, Wirt M, von Scheven E. PMID: 17013844.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    63. Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production. Proc Natl Acad Sci U S A. 2006 May 02; 103(18):7012-7. Hesslein DG, Takaki R, Hermiston ML, Weiss A, Lanier LL. PMID: 16627620.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    64. The juxtamembrane wedge negatively regulates CD45 function in B cells. Immunity. 2005 Dec; 23(6):635-47. Hermiston ML, Tan AL, Gupta VA, Majeti R, Weiss A. PMID: 16356861.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    65. Chapter 114 CD45. Handbook of Cell Signaling. 2003 Jan 1; (Annu. Rev. Immunol.121994):689-691. Zheng Xu, Michelle L. Hermiston, Arthur Weiss. .
      View in: Publisher Site   Mentions:
    66. A practical approach to the evaluation of the anemic child. Pediatr Clin North Am. 2002 Oct; 49(5):877-91. Hermiston ML, Mentzer WC. PMID: 12430617.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    67. Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. J Clin Invest. 2002 Jan; 109(1):9-14. Hermiston ML, Xu Z, Majeti R, Weiss A. PMID: 11781344.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    68. CD45: a critical regulator of signaling thresholds in immune cells. Annu Rev Immunol. 2003; 21:107-37. Hermiston ML, Xu Z, Weiss A. PMID: 12414720.
      View in: PubMed   Mentions: 223     Fields:    Translation:HumansAnimalsCells
    69. Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature. 1997 Apr 24; 386(6627):796-804. Fazeli A, Dickinson SL, Hermiston ML, Tighe RV, Steen RG, Small CG, Stoeckli ET, Keino-Masu K, Masu M, Rayburn H, Simons J, Bronson RT, Gordon JI, Tessier-Lavigne M, Weinberg RA. PMID: 9126737.
      View in: PubMed   Mentions: 191     Fields:    Translation:HumansAnimalsCells
    70. Forced expression of the tumor suppressor adenomatosis polyposis coli protein induces disordered cell migration in the intestinal epithelium. Proc Natl Acad Sci U S A. 1996 Sep 03; 93(18):9588-93. Wong MH, Hermiston ML, Syder AJ, Gordon JI. PMID: 8790374.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    71. Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system. Genes Dev. 1996 Apr 15; 10(8):985-96. Hermiston ML, Wong MH, Gordon JI. PMID: 8608945.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    72. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science. 1995 Nov 17; 270(5239):1203-7. Hermiston ML, Gordon JI. PMID: 7502046.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCells
    73. Organization of the crypt-villus axis and evolution of its stem cell hierarchy during intestinal development. Am J Physiol. 1995 May; 268(5 Pt 1):G813-22. Hermiston ML, Gordon JI. PMID: 7762665.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    74. In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J Cell Biol. 1995 Apr; 129(2):489-506. Hermiston ML, Gordon JI. PMID: 7721948.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    75. Differentiation and self-renewal in the mouse gastrointestinal epithelium. Curr Opin Cell Biol. 1994 Dec; 6(6):795-803. Gordon JI, Hermiston ML. PMID: 7880525.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    76. Chimeric-transgenic mice represent a powerful tool for studying how the proliferation and differentiation programs of intestinal epithelial cell lineages are regulated. Proc Natl Acad Sci U S A. 1993 Oct 01; 90(19):8866-70. Hermiston ML, Green RP, Gordon JI. PMID: 8415622.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    77. Use of transgenic mice to characterize the multipotent intestinal stem cell and to analyze regulation of gene expression in various epithelial cell lineages as a function of their position along the cephalocaudal and crypt-to-villus (or crypt-to-surface epithelial cuff) axes of the gut. Seminars in Cell and Developmental Biology. 1993 Oct 1; 4(5):275-291. Michelle L. Hermiston, Jeffrey I. Gordon. .
      View in: Publisher Site   Mentions:
    78. Simultaneous localization of six antigens in single sections of transgenic mouse intestine using a combination of light and fluorescence microscopy. J Histochem Cytochem. 1992 Sep; 40(9):1283-90. Hermiston ML, Latham CB, Gordon JI, Roth KA. PMID: 1506665.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    79. Use of transgenic mice to infer the biological properties of small intestinal stem cells and to examine the lineage relationships of their descendants. Proc Natl Acad Sci U S A. 1991 Nov 01; 88(21):9407-11. Roth KA, Hermiston ML, Gordon JI. PMID: 1946352.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    80. Isolation of mutants defective in early steps of meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics. 1991 May; 128(1):79-88. Malone RE, Bullard S, Hermiston M, Rieger R, Cool M, Galbraith A. PMID: 2060778.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals