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Matthew Zapala, MD

Title(s)Assistant Professor, Radiology
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone--
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    Collapse Biography 
    Collapse Awards and Honors
    Boston Children’s Hospital2015Pediatric Radiology Fellow Teaching Award
    University of California, San Diego 2009Gold Humanism Honor Society
    University of California, San Diego2009Merck Academic Achievement
    Stanford University1998Departmental Research Honors

    Collapse Overview 
    Collapse Overview
    Matthew Zapala, MD, PhD, is an assistant professor of clinical radiology in the Pediatric Radiology section in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. In 2007, he received his PhD in biomedical science-bioinformatics from the University of California, San Diego, where he also completed his medical degree in 2009. In 2010, he completed his one-year internship from Scripps Mercy Hospital in San Diego, California. From 2010-2014, Dr. Zapala finished his four-year Diagnostic Radiology residency from the University of California, San Diego, followed by a pediatric radiology fellowship from Boston Children’s Hospital/Harvard Medical School in 2015.

    Dr. Zapala is a member of the Radiologic Society of North America, American Roentgen Ray Society and the Society of Pediatric Radiology.

    Specialty:
    Pediatric Radiology

    Expertise:
    Pediatric imaging

    Professional Interests:
    Pediatric radiology, genomics, radiogenomics, bioinformatics, statistical genetics, low dose CT, child abuse, fluoroscopy

    Education and Training:
    • Medical School: University of California, San Diego
    • PhD: University of California, San Diego
    • Internship: Scripps Mercy Hospital, San Diego, California
    • Residency: University of California, San Diego
    • Fellowship: Boston Children's Hospital – Pediatric Radiology

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Monitoring Arteriovenous Malformation Response to Genotype-Targeted Therapy. Pediatrics. 2020 Sep; 146(3). Edwards EA, Phelps AS, Cooke D, Frieden IJ, Zapala MA, Fullerton HJ, Shimano KA. PMID: 32859736.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Evaluating the Performance of Augmented Reality in Displaying Magnetic Resonance Imaging-Derived Three-Dimensional Holographic Models. J Med Imaging Radiat Sci. 2020 03; 51(1):95-102. Chang F, Laguna B, Uribe J, Vu L, Zapala MA, Devincent C, Courtier J. PMID: 31862176.
      View in: PubMed   Mentions:    Fields:    
    3. Improved diagnostic confidence and accuracy of pediatric elbow fractures with digital tomosynthesis. Pediatr Radiol. 2020 03; 50(3):363-370. Zapala MA, Livingston K, Bokhari D, Phelps AS, Courtier JL, Ma C, Seo Y, MacKenzie JD. PMID: 31745596.
      View in: PubMed   Mentions:    Fields:    
    4. Digital tomosynthesis of the pediatric elbow. Pediatr Radiol. 2019 11; 49(12):1643-1651. Zapala MA, Livingston K, Phelps AS, MacKenzie JD. PMID: 31686170.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Assessment of quiet T2 weighted PROPELLER sequence in pediatric abdominal imaging. Clin Imaging. 2019 Jan - Feb; 53:12-16. Zaccagnino E, Devincent C, Leelakanok N, Phelps AS, Zapala M, Worters PW, Courtier J. PMID: 30286312.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    6. Intussusception: past, present and future. Pediatr Radiol. 2017 Aug; 47(9):1101-1108. Edwards EA, Pigg N, Courtier J, Zapala MA, MacKenzie JD, Phelps AS. PMID: 28779197.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    7. Assessing 3D T2 FSE sequence for identification of the normal appendix: working toward a single-sequence MR appendicitis protocol. Emerg Radiol. 2017 Dec; 24(6):653-660. Leelakanok N, Phelps AS, Zapala MA, Kato K, Ohliger M, Li Y, Courtier J. PMID: 28725923.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Thoracic Neoplasms in Children: Contemporary Perspectives and Imaging Assessment. Radiol Clin North Am. 2017 Jul; 55(4):657-676. Zapala MA, Ho-Fung VM, Lee EY. PMID: 28601174.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Musculoskeletal Traumatic Injuries in Children: Characteristic Imaging Findings and Mimickers. Radiol Clin North Am. 2017 Jul; 55(4):785-802. Ho-Fung VM, Zapala MA, Lee EY. PMID: 28601180.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Incidental Findings on Pediatric Abdominal Magnetic Resonance Angiography. Acad Radiol. 2017 09; 24(9):1107-1113. Leelakanok N, Zapala MA, Edwards EA, Phelps AS, Mackenzie JD, Courtier J. PMID: 28285838.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Comparison of Mechanical Versus Hand Administration of IV Contrast Agents for Pediatric Pulmonary CT Angiography. AJR Am J Roentgenol. 2017 Mar; 208(3):632-636. Zapala MA, Zurakowski D, Lee EY. PMID: 28075612.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Magnetic resonance imaging of Müllerian duct anomalies in children. Pediatr Radiol. 2016 May; 46(6):796-805. Li Y, Phelps A, Zapala MA, MacKenzie JD, MacKenzie TC, Courtier J. PMID: 27229498.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Growth recovery lines are more common in infants at high vs. low risk for abuse. Pediatr Radiol. 2016 Aug; 46(9):1275-81. Zapala MA, Tsai A, Kleinman PK. PMID: 27147078.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. The radiogenomic risk score stratifies outcomes in a renal cell cancer phase 2 clinical trial. Eur Radiol. 2016 Aug; 26(8):2798-807. Jamshidi N, Jonasch E, Zapala M, Korn RL, Brooks JD, Ljungberg B, Kuo MD. PMID: 26560727.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    15. The Radiogenomic Risk Score: Construction of a Prognostic Quantitative, Noninvasive Image-based Molecular Assay for Renal Cell Carcinoma. Radiology. 2015 Oct; 277(1):114-23. Jamshidi N, Jonasch E, Zapala M, Korn RL, Aganovic L, Zhao H, Tumkur Sitaram R, Tibshirani RJ, Banerjee S, Brooks JD, Ljungberg B, Kuo MD. PMID: 26402495.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    16. Statistical properties of multivariate distance matrix regression for high-dimensional data analysis. Front Genet. 2012; 3:190. Zapala MA, Schork NJ. PMID: 23060897.
      View in: PubMed   Mentions:
    17. Identification of polymorphisms associated with hypertriglyceridemia and prolonged survival induced by bexarotene in treating non-small cell lung cancer. Anticancer Res. 2011 Jun; 31(6):2303-11. Luo W, Schork NJ, Marschke KB, Ng SC, Hermann TW, Zhang J, Sanders JM, Tooker P, Malo N, Zapala MA, Dziewanowska ZE, Negro-Vilar A, Meglasson MD. PMID: 21737656.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. In silico QTL mapping of basal liver iron levels in inbred mouse strains. Physiol Genomics. 2011 Feb 11; 43(3):136-47. McLachlan S, Lee SM, Steele TM, Hawthorne PL, Zapala MA, Eskin E, Schork NJ, Anderson GJ, Vulpe CD. PMID: 21062905.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    19. The effects of globin on microarray-based gene expression analysis of mouse blood. Mamm Genome. 2010 Jun; 21(5-6):268-75. Winn ME, Zapala MA, Hovatta I, Risbrough VB, Lillie E, Schork NJ. PMID: 20473674.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    20. Gene expression in mouse brain following chronic hypoxia: role of sarcospan in glial cell death. Physiol Genomics. 2008 Feb 19; 32(3):370-9. Zhou D, Wang J, Zapala MA, Xue J, Schork NJ, Haddad GG. PMID: 18056785.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    21. Detecting genetic variation in microarray expression data. Genome Res. 2007 Aug; 17(8):1228-35. Greenhall JA, Zapala MA, Cáceres M, Libiger O, Barlow C, Schork NJ, Lockhart DJ. PMID: 17609390.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    22. Accommodating pathway information in expression quantitative trait locus analysis. Genomics. 2007 Jul; 90(1):132-42. Wessel J, Zapala MA, Schork NJ. PMID: 17493783.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    23. DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies. Genome Biol. 2007; 8(2):R25. Hovatta I, Zapala MA, Broide RS, Schadt EE, Libiger O, Schork NJ, Lockhart DJ, Barlow C. PMID: 17324278.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    24. Multivariate regression analysis of distance matrices for testing associations between gene expression patterns and related variables. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19430-5. Zapala MA, Schork NJ. PMID: 17146048.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimals
    25. Adult mouse brain gene expression patterns bear an embryologic imprint. Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29):10357-62. Zapala MA, Hovatta I, Ellison JA, Wodicka L, Del Rio JA, Tennant R, Tynan W, Broide RS, Helton R, Stoveken BS, Winrow C, Lockhart DJ, Reilly JF, Young WG, Bloom FE, Lockhart DJ, Barlow C. PMID: 16002470.
      View in: PubMed   Mentions: 80     Fields:    Translation:Animals
    26. Elevated gene expression levels distinguish human from non-human primate brains. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):13030-5. Cáceres M, Lachuer J, Zapala MA, Redmond JC, Kudo L, Geschwind DH, Lockhart DJ, Preuss TM, Barlow C. PMID: 14557539.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansAnimals
    27. Software and methods for oligonucleotide and cDNA array data analysis. Genome Biol. 2002; 3(6):SOFTWARE0001. Zapala MA, Lockhart DJ, Pankratz DG, Garcia AJ, Barlow C, Lockhart DJ. PMID: 12093384.
      View in: PubMed   Mentions: 9     Fields: