Aoife O'Donovan, PhD
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| Title | Assistant Professor |
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| School | UCSF School of Medicine |
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| Department | Psychiatry |
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| Address | 3333 Calif. St,Laurel Heights San Francisco CA 94143
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| Phone | 415-476-7748 |
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Biography | Society in Science | 2010
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| 2015 | Branco Weiss Fellowship | | Academy of Behavioral Medicine Research | 2012 | | Neal E. Miller New Investigator Award | | American Psychosomatic Society | 2008 | | Scholar Award | | Psychoneuroimmunology Research Society | 2008
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| 2011 | Trainee Award | | Rotary International | 2007
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| 2009 | Ambassadorial Scholarship | | The Fulbright Program | 2007
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| 2008 | Fulbright Scholarship | | Psychological Society of Ireland | 2007 | | Postgraduate Student of the Year | | Newman Scholarship Program | 2004
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| 2007 | Craig Dobbin Newman Scholarship | | University College Cork | 1998 | | College Scholar Award |
Overview People who experience traumatic or enduring psychological stress are more likely to develop age-related diseases such as cardiovascular, autoimmune and neurodegenerative disorders and to die at a younger age than people who do not experience such psychological stress. My research is focused on revealing how such psychological stress “gets under the skin” and more precisely “into cells” to increase risk for age-related diseases. In my current work, I aim to identify psychological and biological factors that account for the faster rate of biological aging observed in people experiencing psychological stress, and to guide the development of targeted interventions to reduce the deleterious effects of severe stress exposure.
Bibliographic
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O'Donovan A, Rush G, Hoatam G, Hughes BM, McCrohan A, Kelleher C, O'Farrelly C, Malone KM. SUICIDAL IDEATION IS ASSOCIATED WITH ELEVATED INFLAMMATION IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER. Depress Anxiety. 2013 Mar 15.
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Aschbacher K, O'Donovan A, Wolkowitz OM, Dhabhar FS, Su Y, Epel E. Good stress, bad stress and oxidative stress: Insights from anticipatory cortisol reactivity. Psychoneuroendocrinology. 2013 Mar 9.
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O'Donovan A, Slavich GM, Epel ES, Neylan TC. Exaggerated neurobiological sensitivity to threat as a mechanism linking anxiety with increased risk for diseases of aging. Neurosci Biobehav Rev. 2013 Jan; 37(1):96-108.
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Adler N, Pantell MS, O'Donovan A, Blackburn E, Cawthon R, Koster A, Opresko P, Newman A, Harris TB, Epel E. Educational attainment and late life telomere length in the Health, Aging and Body Composition Study. Brain Behav Immun. 2013 Jan; 27(1):15-21.
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O'Donovan A, Neylan TC, Metzler T, Cohen BE. Lifetime exposure to traumatic psychological stress is associated with elevated inflammation in the Heart and Soul Study. Brain Behav Immun. 2012 May; 26(4):642-9.
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O'Donovan A, Tomiyama AJ, Lin J, Puterman E, Adler NE, Kemeny M, Wolkowitz OM, Blackburn EH, Epel ES. Stress appraisals and cellular aging: A key role for anticipatory threat in the relationship between psychological stress and telomere length. Brain Behav Immun. 2012 May; 26(4):573-9.
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Tomiyama AJ, O'Donovan A, Lin J, Puterman E, Lazaro A, Chan J, Dhabhar FS, Wolkowitz O, Kirschbaum C, Blackburn E, Epel E. Does cellular aging relate to patterns of allostasis? An examination of basal and stress reactive HPA axis activity and telomere length. Physiol Behav. 2012 Apr 12; 106(1):40-5.
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Prather AA, Puterman E, Lin J, O'Donovan A, Krauss J, Tomiyama AJ, Epel ES, Blackburn EH. Shorter leukocyte telomere length in midlife women with poor sleep quality. J Aging Res. 2011; 2011:721390.
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Puterman E, O'Donovan A, Adler NE, Tomiyama AJ, Kemeny M, Wolkowitz OM, Epel E. Physical activity moderates effects of stressor-induced rumination on cortisol reactivity. Psychosom Med. 2011 Sep; 73(7):604-11.
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O'Donovan A, Pantell MS, Puterman E, Dhabhar FS, Blackburn EH, Yaffe K, Cawthon RM, Opresko PL, Hsueh WC, Satterfield S, Newman AB, Ayonayon HN, Rubin SM, Harris TB, Epel ES. Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study. PLoS One. 2011; 6(5):e19687.
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O'Donovan A, Epel E, Lin J, Wolkowitz O, Cohen B, Maguen S, Metzler T, Lenoci M, Blackburn E, Neylan TC. Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder. Biol Psychiatry. 2011 Sep 1; 70(5):465-71.
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O'Donovan A, Sun B, Cole S, Rempel H, Lenoci M, Pulliam L, Neylan T. Transcriptional control of monocyte gene expression in post-traumatic stress disorder. Dis Markers. 2011; 30(2-3):123-32.
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Neylan TC, Sun B, Rempel H, Ross J, Lenoci M, O'Donovan A, Pulliam L. Suppressed monocyte gene expression profile in men versus women with PTSD. Brain Behav Immun. 2011 Mar; 25(3):524-31.
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Puterman E, Lin J, Blackburn E, O'Donovan A, Adler N, Epel E. The power of exercise: buffering the effect of chronic stress on telomere length. PLoS One. 2010; 5(5):e10837.
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O'Donovan A, Hughes BM, Slavich GM, Lynch L, Cronin MT, O'Farrelly C, Malone KM. Clinical anxiety, cortisol and interleukin-6: evidence for specificity in emotion-biology relationships. Brain Behav Immun. 2010 Oct; 24(7):1074-7.
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Slavich GM, O'Donovan A, Epel ES, Kemeny ME. Black sheep get the blues: a psychobiological model of social rejection and depression. Neurosci Biobehav Rev. 2010 Sep; 35(1):39-45.
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O'Donovan A, Lin J, Tillie J, Tillie JM, Dhabhar FS, Wolkowitz OM, Wolkowitz O, Blackburn EH, Blackburn E, Epel ES, Epel E. Pessimism correlates with leukocyte telomere shortness and elevated interleukin-6 in post-menopausal women. Brain Behav Immun. 2009 May; 23(4):446-9.
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O'Donovan A, Hughes BM. Access to social support in life and in the laboratory: combined impact on cardiovascular reactivity to stress and state anxiety. J Health Psychol. 2008 Nov; 13(8):1147-56.
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O'Loughlin C, Murphy NF, Conlon C, O'Donovan A, Ledwidge M, McDonald K. Quality of life predicts outcome in a heart failure disease management program. Int J Cardiol. 2010 Feb 18; 139(1):60-7.
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O'Donovan, A.
Hughes, B.M. Factors that moderate the effects of social support on cardiovascular reactivity to stress. Int J Psychol. & Psychol. Therapy. 2008; (8):85-102.
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O'Donovan A, Hughes B. Social support and loneliness in college students: effects on pulse pressure reactivity to acute stress. Int J Adolesc Med Health. 2007 Oct-Dec; 19(4):523-8.
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O'Donovan, A.
Hughes, B.M. Your best interests at heart?. The Psychologist. 2006; (19):216-219.
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Dymond S, O'Hora D, Whelan R, O'Donovan A. Citation Analysis of Skinner's Verbal Behavior: 1984-2004. Behav Anal. 2006; 29(1):75-88.
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