Matthew Nix, PhD

Title(s)Assistant Professor, Laboratory Medicine
SchoolSchool of Medicine
Address185 Berry Street Bldg B, #001
San Francisco CA 94158
Phone--
ORCID ORCID Icon0000-0001-7741-5368 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Alternative target recognition elements for chimeric antigen receptor (CAR) T cells: beyond standard antibody fragments. Cytotherapy. 2024 Mar 02. Nix MA, Wiita AP. PMID: 38466264.
      View in: PubMed   Mentions: 1     Fields:    
    2. Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies. J Immunother Cancer. 2023 11 24; 11(11). Temple WC, Nix MA, Naik A, Izgutdina A, Huang BJ, Wicaksono G, Phojanakong P, Serrano JAC, Young EP, Ramos E, Salangsang F, Steri V, Xirenayi S, Hermiston M, Logan AC, Stieglitz E, Wiita AP. PMID: 38007238; PMCID: PMC10680002.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Structural surfaceomics reveals an AML-specific conformation of integrin β2 as a CAR T cellular therapy target. Nat Cancer. 2023 Nov; 4(11):1592-1609. Mandal K, Wicaksono G, Yu C, Adams JJ, Hoopmann MR, Temple WC, Izgutdina A, Escobar BP, Gorelik M, Ihling CH, Nix MA, Naik A, Xie WH, Hübner J, Rollins LA, Reid SM, Ramos E, Kasap C, Steri V, Serrano JAC, Salangsang F, Phojanakong P, McMillan M, Gavallos V, Leavitt AD, Logan AC, Rooney CM, Eyquem J, Sinz A, Huang BJ, Stieglitz E, Smith CC, Moritz RL, Sidhu SS, Huang L, Wiita AP. PMID: 37904046; PMCID: PMC10663162.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance. Nat Commun. 2022 07 15; 13(1):4121. Ferguson ID, Patiño-Escobar B, Tuomivaara ST, Lin YT, Nix MA, Leung KK, Kasap C, Ramos E, Nieves Vasquez W, Talbot A, Hale M, Naik A, Kishishita A, Choudhry P, Lopez-Girona A, Miao W, Wong SW, Wolf JL, Martin TG, Shah N, Vandenberg S, Prakash S, Besse L, Driessen C, Posey AD, Mullins RD, Eyquem J, Wells JA, Wiita AP. PMID: 35840578; PMCID: PMC9287322.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    5. Author Correction: IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells. Nature. 2021 Apr; 592(7852):E3. Lee J, Robinson ME, Ma N, Artadji D, Ahmed MA, Xiao G, Sadras T, Deb G, Winchester J, Cosgun KN, Geng H, Chan LN, Kume K, Miettinen TP, Zhang Y, Nix MA, Klemm L, Chen CW, Chen J, Khairnar V, Wiita AP, Thomas-Tikhonenko A, Farzan M, Jung JU, Weinstock DM, Manalis SR, Diamond MS, Vaidehi N, Müschen M. PMID: 33712811.
      View in: PubMed   Mentions:    Fields:    
    6. Surface Proteomics Reveals CD72 as a Target for In Vitro-Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL. Cancer Discov. 2021 08; 11(8):2032-2049. Nix MA, Mandal K, Geng H, Paranjape N, Lin YT, Rivera JM, Marcoulis M, White KL, Whitman JD, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, Fattahi F, Hann BC, Satpathy AT, Manglik A, Stieglitz E, Wiita AP. PMID: 33727310; PMCID: PMC8338785.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    7. IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells. Nature. 2020 12; 588(7838):491-497. Lee J, Robinson ME, Ma N, Artadji D, Ahmed MA, Xiao G, Sadras T, Deb G, Winchester J, Cosgun KN, Geng H, Chan LN, Kume K, Miettinen TP, Zhang Y, Nix MA, Klemm L, Chen CW, Chen J, Khairnar V, Wiita AP, Thomas-Tikhonenko A, Farzan M, Jung JU, Weinstock DM, Manalis SR, Diamond MS, Vaidehi N, Müschen M. PMID: 33149299; PMCID: PMC8087162.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    8. Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28046-28055. Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, Lim SA, Zhou XX, Hobman TC, Kortemme T, Wells JA. PMID: 33093202; PMCID: PMC7668070.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    9. Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. bioRxiv. 2020 Aug 04. Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Lim SA, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, Zhou XX, Hobman TC, Kortemme T, Wells JA. PMID: 32766586; PMCID: PMC7402043.
      View in: PubMed   Mentions:
    10. Signalling input from divergent pathways subverts B cell transformation. Nature. 2020 07; 583(7818):845-851. Chan LN, Murakami MA, Robinson ME, Caeser R, Sadras T, Lee J, Cosgun KN, Kume K, Khairnar V, Xiao G, Ahmed MA, Aghania E, Deb G, Hurtz C, Shojaee S, Hong C, Pölönen P, Nix MA, Chen Z, Chen CW, Chen J, Vogt A, Heinäniemi M, Lohi O, Wiita AP, Izraeli S, Geng H, Weinstock DM, Müschen M. PMID: 32699415; PMCID: PMC7394729.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    11. Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis. Leukemia. 2020 10; 34(10):2754-2765. Sarin V, Yu K, Ferguson ID, Gugliemini O, Nix MA, Hann B, Sirota M, Wiita AP. PMID: 32123307; PMCID: PMC7483300.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    12. Electrostatic Similarity Analysis of Human β-Defensin Binding in the Melanocortin System. Biophys J. 2015 Nov 03; 109(9):1946-58. Nix MA, Kaelin CB, Palomino R, Miller JL, Barsh GS, Millhauser GL. PMID: 26536271; PMCID: PMC4643202.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    13. Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors. Chem Biol. 2013 Jun 20; 20(6):784-95. Nix MA, Kaelin CB, Ta T, Weis A, Morton GJ, Barsh GS, Millhauser GL. PMID: 23790489; PMCID: PMC3714013.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    14. Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3. J Invest Dermatol. 2012 Sep; 132(9):2255-62. Swope VB, Jameson JA, McFarland KL, Supp DM, Miller WE, McGraw DW, Patel MA, Nix MA, Millhauser GL, Babcock GF, Abdel-Malek ZA. PMID: 22572817; PMCID: PMC3627493.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    15. Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF. Eur J Immunol. 2011 Nov; 41(11):3291-300. Semple F, MacPherson H, Webb S, Cox SL, Mallin LJ, Tyrrell C, Grimes GR, Semple CA, Nix MA, Millhauser GL, Dorin JR. PMID: 21809339; PMCID: PMC3494976.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    16. New ligands for melanocortin receptors. Int J Obes (Lond). 2008 Dec; 32 Suppl 7:S19-27. Kaelin CB, Candille SI, Yu B, Jackson P, Thompson DA, Nix MA, Binkley J, Millhauser GL, Barsh GS. PMID: 19136986.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    17. A -defensin mutation causes black coat color in domestic dogs. Science. 2007 Nov 30; 318(5855):1418-23. Candille SI, Kaelin CB, Cattanach BM, Yu B, Thompson DA, Nix MA, Kerns JA, Schmutz SM, Millhauser GL, Barsh GS. PMID: 17947548; PMCID: PMC2906624.
      View in: PubMed   Mentions: 151     Fields:    
    18. Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling? Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3638-43. Tomiuk S, Hofmann K, Nix M, Zumbansen M, Stoffel W. PMID: 9520418; PMCID: PMC19888.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    19. Ceramide-independent CD28 and TCR signaling but reduced IL-2 secretion in T cells of acid sphingomyelinase-deficient mice. Eur J Immunol. 1998 Mar; 28(3):874-80. Stoffel B, Bauer P, Nix M, Deres K, Stoffel W. PMID: 9541582.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
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