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    Owen Wolkowitz, MD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentPsychiatry
    Address401 Parnassus Ave, LangPorter
    San Francisco CA 94143
    Phone415-476-7433

       Biography 
       Education and Training
      Institution Degree School or Department Year
      University of MarylandM.D.School of Medicine1979

       ORNG Applications 
       Websites
       Featured Videos
       NIH Grants Awarded
       Global Health
       More Info

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Judd LL, Schettler PJ, Brown ES, Wolkowitz OM, Sternberg EM, Bender BG, Bulloch K, Cidlowski JA, Ronald de Kloet E, Fardet L, Joëls M, Leung DY, McEwen BS, Roozendaal B, Van Rossum EF, Ahn J, Brown DW, Plitt A, Singh G. Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects. Am J Psychiatry. 2014 Oct 1; 171(10):1045-51.
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      2. Verhoeven JE, Révész D, Wolkowitz OM, Penninx BW. Cellular aging in depression: Permanent imprint or reversible process?: An overview of the current evidence, mechanistic pathways, and targets for interventions. Bioessays. 2014 Oct; 36(10):968-78.
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      3. Chen SH, Epel ES, Mellon SH, Lin J, Reus VI, Rosser R, Kupferman E, Burke H, Mahan L, Blackburn EH, Wolkowitz OM. Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults. J Affect Disord. 2014 Dec 1; 169:86-90.
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      4. Révész D, Verhoeven JE, Milaneschi Y, de Geus EJ, Wolkowitz OM, Penninx BW. Dysregulated physiological stress systems and accelerated cellular aging. Neurobiol Aging. 2014 Jun; 35(6):1422-30.
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      5. Verhoeven JE, Révész D, Epel ES, Lin J, Wolkowitz OM, Penninx BW. Major depressive disorder and accelerated cellular aging: results from a large psychiatric cohort study. Mol Psychiatry. 2014 Aug; 19(8):895-901.
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      6. Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT. Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents. Biol Psychiatry. 2013 Dec 15; 74(12):898-907.
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      7. Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT. Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression. J Am Acad Child Adolesc Psychiatry. 2013 Oct; 52(10):1076-1091.e2.
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      8. Yan X, Brown AD, Lazar M, Cressman VL, Henn-Haase C, Neylan TC, Shalev A, Wolkowitz OM, Hamilton SP, Yehuda R, Sodickson DK, Weiner MW, Marmar CR. Spontaneous brain activity in combat related PTSD. Neurosci Lett. 2013 Jun 28; 547:1-5.
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      9. Shalev I, Entringer S, Wadhwa PD, Wolkowitz OM, Puterman E, Lin J, Epel ES. Stress and telomere biology: a lifespan perspective. Psychoneuroendocrinology. 2013 Sep; 38(9):1835-42.
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      10. Aschbacher K, O'Donovan A, Wolkowitz OM, Dhabhar FS, Su Y, Epel E. Good stress, bad stress and oxidative stress: insights from anticipatory cortisol reactivity. Psychoneuroendocrinology. 2013 Sep; 38(9):1698-708.
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      11. Jarcho MR, Slavich GM, Tylova-Stein H, Wolkowitz OM, Burke HM. Dysregulated diurnal cortisol pattern is associated with glucocorticoid resistance in women with major depressive disorder. Biol Psychol. 2013 Apr; 93(1):150-8.
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      12. Rawdin BJ, Mellon SH, Dhabhar FS, Epel ES, Puterman E, Su Y, Burke HM, Reus VI, Rosser R, Hamilton SP, Nelson JC, Wolkowitz OM. Dysregulated relationship of inflammation and oxidative stress in major depression. Brain Behav Immun. 2013 Jul; 31:143-52.
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      13. Woolley JD, Strobl EV, Shelly WB, Karydas AM, Robin Ketelle RN, Wolkowitz OM, Miller BL, Rankin KP. BDNF serum concentrations show no relationship with diagnostic group or medication status in neurodegenerative disease. Curr Alzheimer Res. 2012 Sep; 9(7):815-21.
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      14. O'Donovan A, Tomiyama AJ, Lin J, Puterman E, Adler NE, Kemeny M, Wolkowitz OM, Blackburn EH, Epel ES. Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length. Brain Behav Immun. 2012 May; 26(4):573-9.
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      15. Tomiyama AJ, O'Donovan A, Lin J, Puterman E, Lazaro A, Chan J, Dhabhar FS, Wolkowitz O, Kirschbaum C, Blackburn E, Epel E. Does cellular aging relate to patterns of allostasis? An examination of basal and stress reactive HPA axis activity and telomere length. Physiol Behav. 2012 Apr 12; 106(1):40-5.
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      16. Aschbacher K, Epel E, Wolkowitz OM, Prather AA, Puterman E, Dhabhar FS. Maintenance of a positive outlook during acute stress protects against pro-inflammatory reactivity and future depressive symptoms. Brain Behav Immun. 2012 Feb; 26(2):346-52.
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      17. Aschbacher K, Chen Q, Varga M, Haddad DJ, Yeghiazarians Y, Epel E, Wolkowitz OM, Springer ML. Higher fasting glucose levels are associated with reduced circulating angiogenic cell migratory capacity among healthy individuals. Am J Cardiovasc Dis. 2012; 2(1):12-9.
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      18. Puterman E, O'Donovan A, Adler NE, Tomiyama AJ, Kemeny M, Wolkowitz OM, Epel E. Physical activity moderates effects of stressor-induced rumination on cortisol reactivity. Psychosom Med. 2011 Sep; 73(7):604-11.
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      19. Wolkowitz OM, Wolf J, Shelly W, Rosser R, Burke HM, Lerner GK, Reus VI, Nelson JC, Epel ES, Mellon SH. Serum BDNF levels before treatment predict SSRI response in depression. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1623-30.
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      20. Jeste DV, Wolkowitz OM, Palmer BW. Divergent trajectories of physical, cognitive, and psychosocial aging in schizophrenia. Schizophr Bull. 2011 May; 37(3):451-5.
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      21. O'Donovan A, Epel E, Lin J, Wolkowitz O, Cohen B, Maguen S, Metzler T, Lenoci M, Blackburn E, Neylan TC. Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder. Biol Psychiatry. 2011 Sep 1; 70(5):465-71.
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      22. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Dhabhar FS, Su Y, Reus VI, Rosser R, Burke HM, Kupferman E, Compagnone M, Nelson JC, Blackburn EH. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings. PLoS One. 2011; 6(3):e17837.
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      23. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Reus VI, Rosser R, Burke H, Compagnone M, Nelson JC, Dhabhar FS, Blackburn EH. Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response. Mol Psychiatry. 2012 Feb; 17(2):164-72.
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      24. Wolkowitz OM, Reus VI, Mellon SH. Of sound mind and body: depression, disease, and accelerated aging. Dialogues Clin Neurosci. 2011; 13(1):25-39.
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      25. Jacobs TL, Epel ES, Lin J, Blackburn EH, Wolkowitz OM, Bridwell DA, Zanesco AP, Aichele SR, Sahdra BK, MacLean KA, King BG, Shaver PR, Rosenberg EL, Ferrer E, Wallace BA, Saron CD. Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology. 2011 Jun; 36(5):664-81.
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      26. Lin J, Kroenke CH, Epel E, Kenna HA, Wolkowitz OM, Blackburn E, Rasgon NL. Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline. Brain Res. 2011 Mar 16; 1379:224-31.
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      27. Berger W, Mehra A, Lenoci M, Metzler TJ, Otte C, Tarasovsky G, Mellon SH, Wolkowitz OM, Marmar CR, Neylan TC. Serum brain-derived neurotrophic factor predicts responses to escitalopram in chronic posttraumatic stress disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1; 34(7):1279-84.
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      28. Wolkowitz OM, Epel ES, Reus VI, Mellon SH. Depression gets old fast: do stress and depression accelerate cell aging? Depress Anxiety. 2010 Apr; 27(4):327-38.
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      29. Epel ES, Lin J, Dhabhar FS, Wolkowitz OM, Puterman E, Karan L, Blackburn EH. Dynamics of telomerase activity in response to acute psychological stress. Brain Behav Immun. 2010 May; 24(4):531-9.
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      30. Lin J, Epel E, Cheon J, Kroenke C, Sinclair E, Bigos M, Wolkowitz O, Mellon S, Blackburn E. Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance. J Immunol Methods. 2010 Jan 31; 352(1-2):71-80.
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      31. Wolkowitz OM, Burke H, Epel ES, Reus VI. Glucocorticoids. Mood, memory, and mechanisms. Ann N Y Acad Sci. 2009 Oct; 1179:19-40.
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      32. Dhabhar FS, Burke HM, Epel ES, Mellon SH, Rosser R, Reus VI, Wolkowitz OM. Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression. J Psychiatr Res. 2009 Jul; 43(11):962-9.
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      33. Vinogradov S, Fisher M, Holland C, Shelly W, Wolkowitz O, Mellon SH. Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia? Biol Psychiatry. 2009 Sep 15; 66(6):549-53.
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      34. O'Donovan A, Lin J, Tillie J, Tillie JM, Dhabhar FS, Wolkowitz OM, Wolkowitz O, Blackburn EH, Blackburn E, Epel ES, Epel E. Pessimism correlates with leukocyte telomere shortness and elevated interleukin-6 in post-menopausal women. Brain Behav Immun. 2009 May; 23(4):446-9.
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      35. Maninger N, Wolkowitz OM, Reus VI, Epel ES, Mellon SH. Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS). Front Neuroendocrinol. 2009 Jan; 30(1):65-91.
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      36. Wolkowitz OM, Epel ES, Mellon S. When blue turns to grey: do stress and depression accelerate cell aging? World J Biol Psychiatry. 2008; 9(1):2-5.
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      37. Wolkowitz OM, Lupien SJ, Bigler ED. The "steroid dementia syndrome": a possible model of human glucocorticoid neurotoxicity. Neurocase. 2007 Jun; 13(3):189-200.
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      38. Harris DS, Reus VI, Wolkowitz O, Jacob P, Everhart ET, Wilson M, Mendelson JE, Jones RT. Catecholamine response to methamphetamine is related to glucocorticoid levels but not to pleasurable subjective response. Pharmacopsychiatry. 2006 May; 39(3):100-8.
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      39. Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, Dolbier C, Mendes WB, Blackburn EH. Cell aging in relation to stress arousal and cardiovascular disease risk factors. Psychoneuroendocrinology. 2006 Apr; 31(3):277-87.
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      40. Harris DS, Reus VI, Wolkowitz OM, Mendelson JE, Jones RT. Repeated psychological stress testing in stimulant-dependent patients. Prog Neuropsychopharmacol Biol Psychiatry. 2005 Jun; 29(5):669-77.
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      41. Chao LL, Schuff N, Kramer JH, Du AT, Capizzano AA, O'Neill J, Wolkowitz OM, Jagust WJ, Chui HC, Miller BL, Yaffe K, Weiner MW. Reduced medial temporal lobe N-acetylaspartate in cognitively impaired but nondemented patients. Neurology. 2005 Jan 25; 64(2):282-9.
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      42. Wolkowitz OM, Lupien SJ, Bigler E, Levin RB, Canick J. The "steroid dementia syndrome": an unrecognized complication of glucocorticoid treatment. Ann N Y Acad Sci. 2004 Dec; 1032:191-4.
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      43. Meieran SE, Reus VI, Webster R, Shafton R, Wolkowitz OM. Chronic pregnenolone effects in normal humans: attenuation of benzodiazepine-induced sedation. Psychoneuroendocrinology. 2004 May; 29(4):486-500.
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      44. Ormiston T, Wolkowitz OM, Reus VI, Johnson R, Manfredi F. Hormonal changes with cholesterol reduction: a double-blind pilot study. J Clin Pharm Ther. 2004 Feb; 29(1):71-3.
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      45. Ormiston T, Wolkowitz OM, Reus VI, Manfredi F. Behavioral implications of lowering cholesterol levels: a double-blind pilot study. Psychosomatics. 2003 Sep-Oct; 44(5):412-4.
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      46. Wolkowitz OM, Reus VI. Neurotransmitters, neurosteroids and neurotrophins: new models of the pathophysiology and treatment of depression. World J Biol Psychiatry. 2003 Jul; 4(3):98-102.
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      47. Harris DS, Reus VI, Wolkowitz OM, Mendelson JE, Jones RT. Altering cortisol level does not change the pleasurable effects of methamphetamine in humans. Neuropsychopharmacology. 2003 Sep; 28(9):1677-84.
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      48. Wolkowitz OM, Kramer JH, Reus VI, Costa MM, Yaffe K, Walton P, Raskind M, Peskind E, Newhouse P, Sack D, De Souza E, Sadowsky C, Roberts E. DHEA treatment of Alzheimer's disease: a randomized, double-blind, placebo-controlled study. Neurology. 2003 Apr 8; 60(7):1071-6.
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      49. Seeley WW, Turetsky N, Reus VI, Wolkowitz OM. Benzodiazepines in schizophrenia: prefrontal cortex atrophy predicts clinical response to alprazolam augmentation. World J Biol Psychiatry. 2002 Oct; 3(4):221-4.
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      50. Marco EJ, Wolkowitz OM, Vinogradov S, Poole JH, Lichtmacher J, Reus VI. Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot study. World J Biol Psychiatry. 2002 Jul; 3(3):156-61.
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      51. Kahn AJ, Halloran B, Wolkowitz O, Brizendine L. Dehydroepiandrosterone supplementation and bone turnover in middle-aged to elderly men. J Clin Endocrinol Metab. 2002 Apr; 87(4):1544-9.
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      52. Schuff N, Capizzano AA, Du AT, Amend DL, O'Neill J, Norman D, Kramer J, Jagust W, Miller B, Wolkowitz OM, Yaffe K, Weiner MW. Selective reduction of N-acetylaspartate in medial temporal and parietal lobes in AD. Neurology. 2002 Mar 26; 58(6):928-35.
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      53. Reus VI, Wolkowitz OM. Antiglucocorticoid drugs in the treatment of depression. Expert Opin Investig Drugs. 2001 Oct; 10(10):1789-96.
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      54. Neylan TC, Canick JD, Hall SE, Reus VI, Sapolsky RM, Wolkowitz OM. Cortisol levels predict cognitive impairment induced by electroconvulsive therapy. Biol Psychiatry. 2001 Sep 1; 50(5):331-6.
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      55. Wolkowitz OM, Epel ES, Reus VI. Stress hormone-related psychopathology: pathophysiological and treatment implications. World J Biol Psychiatry. 2001 Jul; 2(3):115-43.
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      56. Harris DS, Wolkowitz OM, Reus VI. Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients. World J Biol Psychiatry. 2001 Apr; 2(2):99-102.
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      57. Heinz A, Weingartner H, George D, Hommer D, Wolkowitz OM, Linnoila M. Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations. Psychiatry Res. 1999 Dec 20; 89(2):97-106.
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      58. Wolkowitz OM, Reus VI. Treatment of depression with antiglucocorticoid drugs. Psychosom Med. 1999 Sep-Oct; 61(5):698-711.
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      59. Costa MM, Reus VI, Wolkowitz OM, Manfredi F, Lieberman M. Estrogen replacement therapy and cognitive decline in memory-impaired post-menopausal women. Biol Psychiatry. 1999 Jul 15; 46(2):182-8.
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      60. Wolkowitz OM, Reus VI, Chan T, Manfredi F, Raum W, Johnson R, Canick J. Antiglucocorticoid treatment of depression: double-blind ketoconazole. Biol Psychiatry. 1999 Apr 15; 45(8):1070-4.
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      61. Wolkowitz OM, Reus VI, Keebler A, Nelson N, Friedland M, Brizendine L, Roberts E. Double-blind treatment of major depression with dehydroepiandrosterone. Am J Psychiatry. 1999 Apr; 156(4):646-9.
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      62. Knutson B, Wolkowitz OM, Cole SW, Chan T, Moore EA, Johnson RC, Terpstra J, Turner RA, Reus VI. Selective alteration of personality and social behavior by serotonergic intervention. Am J Psychiatry. 1998 Mar; 155(3):373-9.
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      63. Reid MS, Ho LB, Tolliver BK, Wolkowitz OM, Berger SP. Partial reversal of stress-induced behavioral sensitization to amphetamine following metyrapone treatment. Brain Res. 1998 Feb 2; 783(1):133-42.
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      64. Wolkowitz OM, Reus VI, Canick J, Levin B, Lupien S. Glucocorticoid medication, memory and steroid psychosis in medical illness. Ann N Y Acad Sci. 1997 Aug 14; 823:81-96.
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      65. Wolkowitz OM, Reus VI, Roberts E, Manfredi F, Chan T, Raum WJ, Ormiston S, Johnson R, Canick J, Brizendine L, Weingartner H. Dehydroepiandrosterone (DHEA) treatment of depression. Biol Psychiatry. 1997 Feb 1; 41(3):311-8.
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      66. Knutson B, Cole S, Wolkowitz O, Reus V, Chan T, Moore E. Serotonergic intervention increases affiliative behavior in humans. Ann N Y Acad Sci. 1997 Jan 15; 807:492-3.
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      67. Reus VI, Wolkowitz OM, Frederick S. Antiglucocorticoid treatments in psychiatry. Psychoneuroendocrinology. 1997; 22 Suppl 1:S121-4.
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      68. Hoff AL, Faustman WO, Wieneke M, Espinoza S, Costa M, Wolkowitz O, Csernansky JG. The effects of clozapine on symptom reduction, neurocognitive function, and clinical management in treatment-refractory state hospital schizophrenic inpatients. Neuropsychopharmacology. 1996 Oct; 15(4):361-9.
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      69. Wolkowitz OM, Reus VI, Manfredi F, Chan T, Ormiston S, Johnson R. Dexamethasone for depression. Am J Psychiatry. 1996 Aug; 153(8):1112; author reply 1112-3.
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      70. Hornig-Rohan M, Wolkowitz OM, Amsterdam JD. Novel strategies for treatment-resistant depression. Psychiatr Clin North Am. 1996 Jun; 19(2):387-405.
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      71. Grasing K, Murphy MG, Lin J, Swigar M, Freedholm D, Clarke L, Zhang J, Wolkowitz OM, Weingartner H, Putnam K, Seibold JR. Human pharmacokinetics and tolerability of L-365,260, a novel cholecystokinin-B antagonist. J Clin Pharmacol. 1996 Apr; 36(4):292-300.
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      72. Wolkowitz OM, Reus VI, Roberts E, Manfredi F, Chan T, Ormiston S, Johnson R, Canick J, Brizendine L, Weingartner H. Antidepressant and cognition-enhancing effects of DHEA in major depression. Ann N Y Acad Sci. 1995 Dec 29; 774:337-9.
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      73. Roy A, Wolkowitz OM, Bissette G, Nemeroff CB. Differences in CSF concentrations of thyrotropin-releasing hormone in depressed patients and normal subjects: negative findings. Am J Psychiatry. 1994 Apr; 151(4):600-2.
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      74. Wolkowitz OM. Prospective controlled studies of the behavioral and biological effects of exogenous corticosteroids. Psychoneuroendocrinology. 1994; 19(3):233-55.
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      75. Rapaport MH, Wolkowitz O, Kelsoe JR, Pato C, Konicki PE, Pickar D. Beneficial effects of nalmefene augmentation in neuroleptic-stabilized schizophrenic patients. Neuropsychopharmacology. 1993 Sep; 9(2):111-5.
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      76. Su TP, Pagliaro M, Schmidt PJ, Pickar D, Wolkowitz O, Rubinow DR. Neuropsychiatric effects of anabolic steroids in male normal volunteers. JAMA. 1993 Jun 2; 269(21):2760-4.
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      77. Wolkowitz OM. Rational polypharmacy in schizophrenia. Ann Clin Psychiatry. 1993 Jun; 5(2):79-90.
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      78. Wolkowitz OM, Weingartner H, Rubinow DR, Jimerson D, Kling M, Berretini W, Thompson K, Breier A, Doran A, Reus VI, et al. Steroid modulation of human memory: biochemical correlates. Biol Psychiatry. 1993 May 15; 33(10):744-6.
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      79. Wolkowitz OM, Reus VI, Manfredi F, Ingbar J, Brizendine L, Weingartner H. Ketoconazole administration in hypercortisolemic depression. Am J Psychiatry. 1993 May; 150(5):810-2.
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      80. Wolkowitz OM, Coppola R, Breier A, Doran AR, Rubinow DR, Berrettini WH, Kling MA, Pickar D. Quantitative electroencephalographic correlates of steroid administration in man. Neuropsychobiology. 1993; 27(4):224-30.
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      81. Goldstein DS, Breier A, Wolkowitz OM, Pickar D, Lenders JW. Plasma levels of catecholamines and corticotrophin during acute glucopenia induced by 2-deoxy-D-glucose in normal man. Clin Auton Res. 1992 Dec; 2(6):359-66.
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      82. Weingartner HJ, Hommer D, Lister RG, Thompson K, Wolkowitz O. Selective effects of triazolam on memory. Psychopharmacology (Berl). 1992; 106(3):341-5.
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      83. Weingartner H, Eckardt M, Molchan S, Sunderland T, Wolkowitz O. Measurement and interpretation of changes in memory in response to drug treatments. Psychopharmacol Bull. 1992; 28(4):331-40.
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      84. Wolkowitz OM, Turetsky N, Reus VI, Hargreaves WA. Benzodiazepine augmentation of neuroleptics in treatment-resistant schizophrenia. Psychopharmacol Bull. 1992; 28(3):291-5.
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      85. Wolkowitz OM, Reus VI, Manfredi F, Ingbar J, Brizendine L. Antiglucocorticoid strategies in hypercortisolemic states. Psychopharmacol Bull. 1992; 28(3):247-51.
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      86. Weingartner HJ, Eckardt MJ, Hommer DW, Mendelson W, Wolkowitz OM. Specificity of memory impairments with triazolam use. Lancet. 1991 Oct 5; 338(8771):883-4.
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      87. Wolkowitz OM, Pickar D. Benzodiazepines in the treatment of schizophrenia: a review and reappraisal. Am J Psychiatry. 1991 Jun; 148(6):714-26.
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      88. Deicken RF, Reus VI, Manfredi L, Wolkowitz OM. MRI deep white matter hyperintensity in a psychiatric population. Biol Psychiatry. 1991 May 1; 29(9):918-22.
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      89. Wolkowitz OM, Bartko JJ, Pickar D. Drug trials and heterogeneity in schizophrenia: the mean is not the end. Biol Psychiatry. 1990 Dec 15; 28(12):1021-5.
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      90. Breier A, Wolkowitz OM, Roy A, Potter WZ, Pickar D. Plasma norepinephrine in chronic schizophrenia. Am J Psychiatry. 1990 Nov; 147(11):1467-70.
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      91. Wolkowitz OM, Rubinow D, Doran AR, Breier A, Berrettini WH, Kling MA, Pickar D. Prednisone effects on neurochemistry and behavior. Preliminary findings. Arch Gen Psychiatry. 1990 Oct; 47(10):963-8.
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      92. Wolkowitz OM, Reus VI, Weingartner H, Thompson K, Breier A, Doran A, Rubinow D, Pickar D. Cognitive effects of corticosteroids. Am J Psychiatry. 1990 Oct; 147(10):1297-303.
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      93. Wolkowitz OM, Gertz B, Weingartner H, Beccaria L, Thompson K, Liddle RA. Hunger in humans induced by MK-329, a specific peripheral-type cholecystokinin receptor antagonist. Biol Psychiatry. 1990 Jul 15; 28(2):169-73.
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      94. Pickar D, Breier A, Hsiao JK, Doran AR, Wolkowitz OM, Pato CN, Konicki PE, Potter WZ. Cerebrospinal fluid and plasma monoamine metabolites and their relation to psychosis. Implications for regional brain dysfunction in schizophrenia. Arch Gen Psychiatry. 1990 Jul; 47(7):641-8.
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      95. Doran AR, Labarca R, Wolkowitz OM, Roy A, Douillet P, Pickar D. Circadian variation of plasma homovanillic acid levels is attenuated by fluphenazine in patients with schizophrenia. Arch Gen Psychiatry. 1990 Jun; 47(6):558-63.
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      96. Wolkowitz OM. Use of the dexamethasone suppression test with mentally retarded persons: review and recommendations. Am J Ment Retard. 1990 Mar; 94(5):509-14.
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      97. Wolkowitz O. Suicidality and corticosteroid psychosis. Biol Psychiatry. 1990 Feb 15; 27(4):459.
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      98. Wolkowitz OM, Papadopoulos NM, Costello R, Breier A, Doran AR, Pickar D, Rubinow D. Prednisone effects on blood-brain barrier permeability and CNS IgG synthesis in healthy humans. Psychoneuroendocrinology. 1990; 15(2):155-8.
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      99. Pickar D, Litman RE, Konicki PE, Wolkowitz OM, Breier A. Neurochemical and neural mechanisms of positive and negative symptoms in schizophrenia. Mod Probl Pharmacopsychiatry. 1990; 24:124-51.
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      100. Rubinow DR, Denicoff KD, Schmidt PJ, Wolkowitz OM, Joffe RT. Models for research in consultation psychiatry. Adv Psychosom Med. 1990; 20:125-35.
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      101. Wolkowitz OM, Breier A, Doran A, Lucas P, Kelsoe J, Paul SM, Pickar D. Alprazolam augmentation of neuroleptics in schizophrenia. Am J Psychiatry. 1989 Aug; 146(8):1087-8.
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      102. Wolkowitz OM, Doran A, Breier A, Roy A, Pickar D. Specificity of plasma HVA response to dexamethasone in psychotic depression. Psychiatry Res. 1989 Aug; 29(2):177-86.
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      103. Bracha HS, Wolkowitz OM, Lohr JB, Karson CN, Bigelow LB. High prevalence of visual hallucinations in research subjects with chronic schizophrenia. Am J Psychiatry. 1989 Apr; 146(4):526-8.
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      104. Wolkowitz OM. Long-lasting behavioral changes following prednisone withdrawal. JAMA. 1989 Mar 24-31; 261(12):1731-2.
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      105. Roy A, Wolkowitz O, Doran A, Pickar D. TRH test in schizophrenic patients and controls. Biol Psychiatry. 1989 Feb 15; 25(4):523-6.
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      106. Doran AR, Rubinow DR, Wolkowitz OM, Roy A, Breier A, Pickar D. Fluphenazine treatment reduces CSF somatostatin in patients with schizophrenia: correlations with CSF HVA. Biol Psychiatry. 1989 Feb 15; 25(4):431-9.
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      107. Pato CN, Wolkowitz OM, Rapaport M, Schulz SC, Pickar D. Benzodiazepine augmentation of neuroleptic treatment in patients with schizophrenia. Psychopharmacol Bull. 1989; 25(2):263-6.
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      108. Breier A, Kelsoe JR, Kirwin PD, Beller SA, Wolkowitz OM, Pickar D. Early parental loss and development of adult psychopathology. Arch Gen Psychiatry. 1988 Nov; 45(11):987-93.
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      109. Wolkowitz OM, Doran AR, Cohen MR, Cohen RM, Wise TN, Pickar D. Single-dose naloxone acutely reduces eating in obese humans: behavioral and biochemical effects. Biol Psychiatry. 1988 Aug; 24(4):483-7.
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      110. Breier A, Wolkowitz OM, Doran AR, Bellar S, Pickar D. Neurobiological effects of lumbar puncture stress in psychiatric patients and healthy volunteers. Psychiatry Res. 1988 Aug; 25(2):187-94.
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      111. Wolkowitz OM, Breier A, Doran A, Kelsoe J, Lucas P, Paul SM, Pickar D. Alprazolam augmentation of the antipsychotic effects of fluphenazine in schizophrenic patients. Preliminary results. Arch Gen Psychiatry. 1988 Jul; 45(7):664-71.
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      112. Sommer BR, Wolkowitz OM. RBC folic acid levels and cognitive performance in elderly patients: a preliminary report. Biol Psychiatry. 1988 Jul; 24(3):352-4.
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      113. Wolkowitz OM. Dexamethasone effects on dopamine and the "prolactin suppression test". Acta Psychiatr Scand. 1988 May; 77(5):618-9.
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      114. Joffe RT, Wolkowitz OM, Rubinow DR, Denicoff K, Tsokos G, Pillemer S. Alternate-day corticosteroid treatment, mood and plasma HVA in patients with systemic lupus erythematosus. Neuropsychobiology. 1988; 19(1):17-9.
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      115. Breier A, Wolkowitz OM, Rapaport M, Paul SM, Pickar D. Metabolic stress effects in normal volunteers and schizophrenic patients. Psychopharmacol Bull. 1988; 24(3):431-3.
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      116. Wolkowitz OM, Breier A, Doran A, Rubinow D, Berrettini W, Coppola R, Gold P, Pickar D. Prednisone-induced behavioral and biological changes in medically healthy volunteers. Psychopharmacol Bull. 1988; 24(3):492-4.
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      117. Breier A, Arora PK, Wolkowitz OM, Pickar D, Paul SM. Metabolic stress produces rapid immunosuppression in humans. Arch Gen Psychiatry. 1987 Dec; 44(12):1108-9.
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      118. Doran AR, Boronow J, Weinberger DR, Wolkowitz OM, Breier A, Pickar D. Structural brain pathology in schizophrenia revisited. Prefrontal cortex pathology is inversely correlated with cerebrospinal fluid levels of homovanillic acid. Neuropsychopharmacology. 1987 Dec; 1(1):25-32.
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      119. Breier A, Wolkowitz OM, Doran AR, Roy A, Boronow J, Hommer DW, Pickar D. Neuroleptic responsivity of negative and positive symptoms in schizophrenia. Am J Psychiatry. 1987 Dec; 144(12):1549-55.
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      120. Lucas PB, Gardner DL, Wolkowitz OM, Cowdry RW. Dysphoria associated with methylphenidate infusion in borderline personality disorder. Am J Psychiatry. 1987 Dec; 144(12):1577-9.
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      121. Breier A, Albus M, Pickar D, Zahn TP, Wolkowitz OM, Paul SM. Controllable and uncontrollable stress in humans: alterations in mood and neuroendocrine and psychophysiological function. Am J Psychiatry. 1987 Nov; 144(11):1419-25.
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      122. Wolkowitz OM, Rubinow DR, Breier A, Doran AR, Davis C, Pickar D. Prednisone decreases CSF somatostatin in healthy humans: implications for neuropsychiatric illness. Life Sci. 1987 Oct 19; 41(16):1929-33.
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      123. Wolkowitz OM, Doran AR, Breier A, Roy A, Jimerson DC, Sutton ME, Golden RN, Paul SM, Pickar D. The effects of dexamethasone on plasma homovanillic acid and 3-methoxy-4-hydroxyphenylglycol. Evidence for abnormal corticosteroid-catecholamine interactions in major depression. Arch Gen Psychiatry. 1987 Sep; 44(9):782-9.
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      124. Pickar D, Wolkowitz OM, Doran AR, Labarca R, Roy A, Breier A, Narang PK. Clinical and biochemical effects of verapamil administration to schizophrenic patients. Arch Gen Psychiatry. 1987 Feb; 44(2):113-8.
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      125. Wolkowitz OM, Weingartner H, Thompson K, Pickar D, Paul SM, Hommer DW. Diazepam-induced amnesia: a neuropharmacological model of an "organic amnestic syndrome". Am J Psychiatry. 1987 Jan; 144(1):25-9.
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      126. Hommer DW, Matsuo V, Wolkowitz OM, Weingartner H, Paul SM. Pharmacodynamic approaches to benzodiazepine action in man. Psychopharmacol Ser. 1987; 3:52-61.
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      127. Pickar D, Wolkowitz OM, Labarca R, Doran AR, Breier A, Paul SM. Biochemical alterations produced by neuroleptics in man: studies of plasma homovanillic acid in schizophrenic patients. Psychopharmacol Ser. 1987; 3:248-54.
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      128. Lucas PB, Gardner DL, Wolkowitz OM, Tucker EE, Cowdry RW. Methylphenidate-induced cardiac arrhythmias. N Engl J Med. 1986 Dec 4; 315(23):1485.
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      129. Amsterdam JD, Henle W, Winokur A, Wolkowitz OM, Pickar D, Paul SM. Serum antibodies to Epstein-Barr virus in patients with major depressive disorder. Am J Psychiatry. 1986 Dec; 143(12):1593-6.
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      130. Roy A, Pickar D, Doran A, Wolkowitz O, Gallucci W, Chrousos G, Gold P. The corticotropin-releasing hormone stimulation test in chronic schizophrenia. Am J Psychiatry. 1986 Nov; 143(11):1393-7.
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      131. Pickar D, Labarca R, Doran AR, Wolkowitz OM, Roy A, Breier A, Linnoila M, Paul SM. Longitudinal measurement of plasma homovanillic acid levels in schizophrenic patients. Correlation with psychosis and response to neuroleptic treatment. Arch Gen Psychiatry. 1986 Jul; 43(7):669-76.
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      132. Hommer DW, Matsuo V, Wolkowitz O, Chrousos G, Greenblatt DJ, Weingartner H, Paul SM. Benzodiazepine sensitivity in normal human subjects. Arch Gen Psychiatry. 1986 Jun; 43(6):542-51.
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      133. Wolkowitz O, Sutton M, Koulu M, Labarca R, Wilkinson L, Doran A, Hauger R, Pickar D, Crawley J. Chronic corticosterone administration in rats: behavioral and biochemical evidence of increased central dopaminergic activity. Eur J Pharmacol. 1986 Apr 2; 122(3):329-38.
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      134. Wolkowitz OM, Doran AR, Breier A, Cohen MR, Pickar D. Endogenous opioid regulation of hypothalamo-pituitary-adrenal axis activity in schizophrenia. Biol Psychiatry. 1986 Apr; 21(4):366-73.
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      135. Roy A, Gold P, Pickar D, Wolkowitz OM, Chrousos G, Paul SM. Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls. J Affect Disord. 1986 Mar-Apr; 10(2):95-9.
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      136. Pickar D, Roy A, Breier A, Doran A, Wolkowitz O, Colison J, Agren H. Suicide and aggression in schizophrenia. Neurobiologic correlates. Ann N Y Acad Sci. 1986; 487:189-96.
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      137. Wolkowitz OM, Pickar D, Doran AR, Breier A, Tarell J, Paul SM. Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia. Am J Psychiatry. 1986 Jan; 143(1):85-7.
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      138. Wolkowitz OM, Sutton ME, Doran AR, Labarca R, Roy A, Thomas JW, Pickar D, Paul SM. Dexamethasone increases plasma HVA but not MHPG in normal humans. Psychiatry Res. 1985 Oct; 16(2):101-9.
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      139. Wolkowitz OM, Doran AR, Cohen MR, Cohen RM, Wise TN, Pickar D. Effect of naloxone on food consumption in obesity. N Engl J Med. 1985 Aug 1; 313(5):327.
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      140. Doran AR, Roy A, Wolkowitz OM. Self-destructive dermatoses. Psychiatr Clin North Am. 1985 Jun; 8(2):291-8.
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      141. Wolkowitz OM, Roy A, Doran AR. Pathologic gambling and other risk-taking pursuits. Psychiatr Clin North Am. 1985 Jun; 8(2):311-22.
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      142. Doran AR, Narang PK, Meigs CY, Wolkowitz OM, Roy A, Breier A, Pickar D. Verapamil concentrations in cerebrospinal fluid after oral administration. N Engl J Med. 1985 May 9; 312(19):1261-2.
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      143. Wolkowitz OM, Paul SM. Neural and molecular mechanisms in anxiety. Psychiatr Clin North Am. 1985 Mar; 8(1):145-58.
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      144. Wolkowitz OM, Tinklenberg JR. Naloxone's effect on cognitive functioning in drug-free and diazepam-treated normal humans. Psychopharmacology (Berl). 1985; 85(2):221-3.
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      145. Doran AR, Pickar D, Labarca R, Douillet P, Wolkowitz OM, Thomas JW, Roy A, Paul SM. Evidence for a daily rhythm of plasma HVA in normal controls but not in schizophrenic patients. Psychopharmacol Bull. 1985; 21(3):694-7.
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      146. Wolkowitz OM, Tinklenberg JR, Weingartner H. A psychopharmacological perspective of cognitive functions. II. Specific pharmacologic agents. Neuropsychobiology. 1985; 14(3):133-56.
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      147. Wolkowitz OM, Tinklenberg JR, Weingartner H. A psychopharmacological perspective of cognitive functions. I. Theoretical overview and methodological considerations. Neuropsychobiology. 1985; 14(2):88-96.
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      148. Stillman R, DeRenzo E, Wolkowitz O, Allen H, Lehman RA, Wyatt RJ. Development of differences in response latencies to right and left visual fields. Brain Cogn. 1984 Jul; 3(3):335-42.
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      149. Stillman RC, Wolkowitz O, Weingartner H, Waldman I, DeRenzo EV, Wyatt RJ. Marijuana: differential effects on right and left hemisphere functions in man. Life Sci. 1977 Dec 15; 21(12):1793-9.
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