Synthia Mellon, PhD

Title(s)Professor, Ob/Gyn, Reproductive Sciences
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSW, #1464G
San Francisco CA 94143
Phone415-502-4844
PronounsShe/Her/Hers
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    Collapse Research 
    Collapse Research Activities and Funding
    Cell Aging in Major Depression
    NIH R01MH083784Jul 1, 2008 - Feb 28, 2021
    Role: Co-Principal Investigator
    Origins and Biological Consequences of Human Infertility
    NIH U54HD055764May 3, 2007 - Mar 31, 2017
    Role: Co-Investigator
    Center for Research, Innovation and Training in Reproduction and Infertility
    NIH P50HD055764Apr 1, 2007 - Mar 31, 2023
    Role: Co-Investigator
    Neurosteroids in health and disease
    NIH U01NS049462Jun 15, 2005 - May 31, 2012
    Role: Principal Investigator
    Regulation of Reproduction
    NIH R01HD027970Aug 1, 1991 - Jun 30, 2006
    Role: Principal Investigator
    HORMONAL REGULATION OF STEROIDOGENESIS
    NIH R29HD022013Aug 1, 1986 - Jul 31, 1991
    Role: Principal Investigator
    HORMONAL REGULATION OF STEROIDOGENESIS
    NIH R23HD022013Aug 1, 1986 - Jul 31, 1989
    Role: Principal Investigator
    Integrated Training in Reproductive Sciences
    NIH T32HD007263Jul 1, 1983 - Apr 30, 2024
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Serum brain-derived neurotrophic factor, Val66Met polymorphism and open-label SSRI treatment response in Major Depressive Disorder. Psychoneuroendocrinology. 2024 Jul; 165:107045. Smit AJT, Wu GWY, Rampersaud R, Reus VI, Wolkowitz OM, Mellon SH. PMID: 38636352.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    2. Circulating cell-free mitochondrial DNA levels and glucocorticoid sensitivity in a cohort of male veterans with and without combat-related PTSD. Transl Psychiatry. 2024 Jan 10; 14(1):22. Blalock ZN, Wu GWY, Lindqvist D, Trumpff C, Flory JD, Lin J, Reus VI, Rampersaud R, Hammamieh R, Gautam A, SBPBC, Doyle FJ, Marmar CR, Jett M, Yehuda R, Wolkowitz OM, Mellon SH. PMID: 38200001; PMCID: PMC10781666.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Integrated analysis of proteomics, epigenomics and metabolomics data revealed divergent pathway activation patterns in the recent versus chronic post-traumatic stress disorder. Brain Behav Immun. 2023 10; 113:303-316. Muhie S, Gautam A, Misganaw B, Yang R, Mellon SH, Hoke A, Flory J, Daigle B, Swift K, PTSD Systems Biology Consortium, Hood L, Doyle FJ, Wolkowitz OM, Marmar CR, Ressler K, Yehuda R, Hammamieh R, Jett M. PMID: 37516387.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    4. Shorter telomere length predicts poor antidepressant response and poorer cardiometabolic indices in major depression. Sci Rep. 2023 06 23; 13(1):10238. Rampersaud R, Wu GWY, Reus VI, Lin J, Blackburn EH, Epel ES, Hough CM, Mellon SH, Wolkowitz OM. PMID: 37353495; PMCID: PMC10290110.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Molecular signatures of post-traumatic stress disorder in war-zone-exposed veteran and active-duty soldiers. Cell Rep Med. 2023 05 16; 4(5):101045. Muhie S, Gautam A, Yang R, Misganaw B, Daigle BJ, Mellon SH, Flory JD, Abu-Amara D, Lee I, Wang K, Rampersaud R, PTSD Systems Biology Consortium, Hood L, Yehuda R, Marmar CR, Wolkowitz OM, Ressler KJ, Doyle FJ, Hammamieh R, Jett M. PMID: 37196634; PMCID: PMC10213980.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. The Genetic Basis for the Increased Prevalence of Metabolic Syndrome among Post-Traumatic Stress Disorder Patients. Int J Mol Sci. 2022 Oct 19; 23(20). Misganaw B, Yang R, Gautam A, Muhie S, Mellon SH, Wolkowitz OM, Ressler KJ, Doyle FJ, Marmar CR, Jett M, Hammamieh R. PMID: 36293361; PMCID: PMC9604263.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Dimensions of childhood adversity differentially affect biological aging in major depression. Transl Psychiatry. 2022 10 04; 12(1):431. Rampersaud R, Protsenko E, Yang R, Reus V, Hammamieh R, Wu GWY, Epel E, Jett M, Gautam A, Mellon SH, Wolkowitz OM. PMID: 36195591; PMCID: PMC9532396.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    8. Blood-based mitochondrial respiratory chain function in major depression. Transl Psychiatry. 2021 11 17; 11(1):593. Fernström J, Mellon SH, McGill MA, Picard M, Reus VI, Hough CM, Lin J, Epel ES, Wolkowitz OM, Lindqvist D. PMID: 34789750; PMCID: PMC8599473.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    9. Abnormal levels of mitochondrial proteins in plasma neuronal extracellular vesicles in major depressive disorder. Mol Psychiatry. 2021 12; 26(12):7355-7362. Goetzl EJ, Wolkowitz OM, Srihari VH, Reus VI, Goetzl L, Kapogiannis D, Heninger GR, Mellon SH. PMID: 34471251; PMCID: PMC8872999.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    10. Correction: A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD. Mol Psychiatry. 2021 Sep; 26(9):5010. Yang R, Wu GWY, Verhoeven JE, Gautam A, Reus VI, Kang JI, Flory JD, Abu-Amara D, PTSD Systems Biology Consortium, Hood L, Doyle FJ, Yehuda R, Marmar CR, Jett M, Hammamieh R, Mellon SH, Wolkowitz OM. PMID: 32651479.
      View in: PubMed   Mentions: 1     Fields:    
    11. Serum brain-derived neurotrophic factor remains elevated after long term follow-up of combat veterans with chronic post-traumatic stress disorder. Psychoneuroendocrinology. 2021 Jul 22; 134:105360. Wu GWY, Wolkowitz OM, Reus VI, Kang JI, Elnar M, Sarwal R, Flory JD, Abu-Amara D, Hammamieh R, Gautam A, Doyle FJ, Yehuda R, Marmar CR, Jett M, Mellon SH, SBPBC. PMID: 34757255.
      View in: PubMed   Mentions: 4     Fields:    
    12. Utilization of machine learning for identifying symptom severity military-related PTSD subtypes and their biological correlates. Transl Psychiatry. 2021 04 20; 11(1):227. Siegel CE, Laska EM, Lin Z, Xu M, Abu-Amara D, Jeffers MK, Qian M, Milton N, Flory JD, Hammamieh R, Daigle BJ, Gautam A, Dean KR, Reus VI, Wolkowitz OM, Mellon SH, Ressler KJ, Yehuda R, Wang K, Hood L, Doyle FJ, Jett M, Marmar CR. PMID: 33879773; PMCID: PMC8058082.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    13. "GrimAge," an epigenetic predictor of mortality, is accelerated in major depressive disorder. Transl Psychiatry. 2021 04 06; 11(1):193. Protsenko E, Yang R, Nier B, Reus V, Hammamieh R, Rampersaud R, Wu GWY, Hough CM, Epel E, Prather AA, Jett M, Gautam A, Mellon SH, Wolkowitz OM. PMID: 33820909; PMCID: PMC8021561.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    14. Epigenetic biotypes of post-traumatic stress disorder in war-zone exposed veteran and active duty males. Mol Psychiatry. 2021 08; 26(8):4300-4314. Yang R, Gautam A, Getnet D, Daigle BJ, Miller S, Misganaw B, Dean KR, Kumar R, Muhie S, Wang K, Lee I, Abu-Amara D, Flory JD, PTSD Systems Biology Consortium, Hood L, Wolkowitz OM, Mellon SH, Doyle FJ, Yehuda R, Marmar CR, Ressler KJ, Hammamieh R, Jett M. PMID: 33339956; PMCID: PMC8550967.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    15. Pre-deployment risk factors for PTSD in active-duty personnel deployed to Afghanistan: a machine-learning approach for analyzing multivariate predictors. Mol Psychiatry. 2021 09; 26(9):5011-5022. Schultebraucks K, Qian M, Abu-Amara D, Dean K, Laska E, Siegel C, Gautam A, Guffanti G, Hammamieh R, Misganaw B, Mellon SH, Wolkowitz OM, Blessing EM, Etkin A, Ressler KJ, Doyle FJ, Jett M, Marmar CR. PMID: 32488126; PMCID: PMC8589682.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    16. Pre-treatment allostatic load and metabolic dysregulation predict SSRI response in major depressive disorder: a preliminary report. Psychol Med. 2021 09; 51(12):2117-2125. Hough CM, Bersani FS, Mellon SH, Morford AE, Lindqvist D, Reus VI, Epel ES, Wolkowitz OM. PMID: 32438932.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    17. A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD. Mol Psychiatry. 2021 09; 26(9):4999-5009. Yang R, Wu GWY, Verhoeven JE, Gautam A, Reus VI, Kang JI, Flory JD, Abu-Amara D, PTSD Systems Biology Consortium, Hood L, Doyle FJ, Yehuda R, Marmar CR, Jett M, Hammamieh R, Mellon SH, Wolkowitz OM. PMID: 32382136.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    18. Role of enhanced glucocorticoid receptor sensitivity in inflammation in PTSD: insights from computational model for circadian-neuroendocrine-immune interactions. Am J Physiol Endocrinol Metab. 2020 07 01; 319(1):E48-E66. Somvanshi PR, Mellon SH, Yehuda R, Flory JD, Makotkine I, Bierer L, Marmar C, Jett M, Doyle FJ. PMID: 32315214.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    19. Effect of Combat Exposure and Posttraumatic Stress Disorder on Telomere Length and Amygdala Volume. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 07; 5(7):678-687. Kang JI, Mueller SG, Wu GWY, Lin J, Ng P, Yehuda R, Flory JD, Abu-Amara D, Reus VI, Gautam A, PTSD Systems Biology Consortium, Hammamieh R, Doyle FJ, Jett M, Marmar CR, Mellon SH, Wolkowitz OM. PMID: 32439402.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    20. Vitamin D and inflammation in major depressive disorder. J Affect Disord. 2020 04 15; 267:33-41. Grudet C, Wolkowitz OM, Mellon SH, Malm J, Reus VI, Brundin L, Nier BM, Dhabhar FS, Hough CM, Westrin Å, Lindqvist D. PMID: 32063570; PMCID: PMC10662683.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    21. Novel Pharmacological Targets for Combat PTSD-Metabolism, Inflammation, The Gut Microbiome, and Mitochondrial Dysfunction. Mil Med. 2020 01 07; 185(Suppl 1):311-318. Bersani FS, Mellon SH, Lindqvist D, Kang JI, Rampersaud R, Somvanshi PR, Doyle FJ, Hammamieh R, Jett M, Yehuda R, Marmar CR, Wolkowitz OM. PMID: 32074311; PMCID: PMC8483162.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    22. Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder. Mol Psychiatry. 2020 12; 25(12):3337-3349. Dean KR, Hammamieh R, Mellon SH, Abu-Amara D, Flory JD, Guffanti G, Wang K, Daigle BJ, Gautam A, Lee I, Yang R, Almli LM, Bersani FS, Chakraborty N, Donohue D, Kerley K, Kim TK, Laska E, Young Lee M, Lindqvist D, Lori A, Lu L, Misganaw B, Muhie S, Newman J, Price ND, Qin S, Reus VI, Siegel C, Somvanshi PR, Thakur GS, Zhou Y, PTSD Systems Biology Consortium, Hood L, Ressler KJ, Wolkowitz OM, Yehuda R, Jett M, Doyle FJ, Marmar C. PMID: 31501510; PMCID: PMC7714692.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    23. Accelerated aging in serious mental disorders. Curr Opin Psychiatry. 2019 09; 32(5):381-387. Bersani FS, Mellon SH, Reus VI, Wolkowitz OM. PMID: 31145144; PMCID: PMC6707774.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    24. Cortisol, moderated by age, is associated with antidepressant treatment outcome and memory improvement in Major Depressive Disorder: A retrospective analysis. Psychoneuroendocrinology. 2019 11; 109:104386. Jain FA, Connolly CG, Reus VI, Meyerhoff DJ, Yang TT, Mellon SH, Mackin S, Hough CM, Morford A, Wolkowitz OM. PMID: 31382170; PMCID: PMC6842706.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Mechanistic inferences on metabolic dysfunction in posttraumatic stress disorder from an integrated model and multiomic analysis: role of glucocorticoid receptor sensitivity. Am J Physiol Endocrinol Metab. 2019 11 01; 317(5):E879-E898. Somvanshi PR, Mellon SH, Flory JD, Abu-Amara D, PTSD Systems Biology Consortium;, Wolkowitz OM, Yehuda R, Jett M, Hood L, Marmar C, Doyle FJ. PMID: 31322414; PMCID: PMC6879860.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    26. Accelerating research on biological aging and mental health: Current challenges and future directions. Psychoneuroendocrinology. 2019 08; 106:293-311. Han LKM, Verhoeven JE, Tyrka AR, Penninx BWJH, Wolkowitz OM, Månsson KNT, Lindqvist D, Boks MP, Révész D, Mellon SH, Picard M. PMID: 31154264; PMCID: PMC6589133.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    27. Metabolomic analysis of male combat veterans with post traumatic stress disorder. PLoS One. 2019; 14(3):e0213839. Mellon SH, Bersani FS, Lindqvist D, Hammamieh R, Donohue D, Dean K, Jett M, Yehuda R, Flory J, Reus VI, Bierer LM, Makotkine I, Abu Amara D, Henn Haase C, Coy M, Doyle FJ, Marmar C, Wolkowitz OM. PMID: 30883584; PMCID: PMC6422302.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    28. Low serum brain-derived neurotrophic factor is associated with suicidal ideation in major depressive disorder. Psychiatry Res. 2019 03; 273:108-113. Khan MS, Wu GWY, Reus VI, Hough CM, Lindqvist D, Westrin Å, Nier BM, Wolkowitz OM, Mellon SH. PMID: 30640051; PMCID: PMC6561801.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    29. Epigenetic Age in Male Combat-Exposed War Veterans: Associations with Posttraumatic Stress Disorder Status. Mol Neuropsychiatry. 2018 Oct; 4(2):90-99. Verhoeven JE, Yang R, Wolkowitz OM, Bersani FS, Lindqvist D, Mellon SH, Yehuda R, Flory JD, Lin J, Abu-Amara D, Makotkine I, Marmar C, Jett M, Hammamieh R. PMID: 30397597; PMCID: PMC6206951.
      View in: PubMed   Mentions: 26  
    30. Posttraumatic stress disorder, symptoms, and white matter abnormalities among combat-exposed veterans. Brain Imaging Behav. 2018 Aug; 12(4):989-999. Aschbacher K, Mellon SH, Wolkowitz OM, Henn-Haase C, Yehuda R, Flory JD, Bierer LM, Abu-Amara D, Marmar CR, Mueller SG. PMID: 28823023.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    31. Metabolism, Metabolomics, and Inflammation in Posttraumatic Stress Disorder. Biol Psychiatry. 2018 05 15; 83(10):866-875. Mellon SH, Gautam A, Hammamieh R, Jett M, Wolkowitz OM. PMID: 29628193.
      View in: PubMed   Mentions: 82     Fields:    Translation:Humans
    32. Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder. Neuropsychopharmacology. 2018 06; 43(7):1557-1564. Lindqvist D, Wolkowitz OM, Picard M, Ohlsson L, Bersani FS, Fernström J, Westrin Å, Hough CM, Lin J, Reus VI, Epel ES, Mellon SH. PMID: 29453441; PMCID: PMC5983469.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCellsCTClinical Trials
    33. Increased circulating blood cell counts in combat-related PTSD: Associations with inflammation and PTSD severity. Psychiatry Res. 2017 12; 258:330-336. Lindqvist D, Mellon SH, Dhabhar FS, Yehuda R, Grenon SM, Flory JD, Bierer LM, Abu-Amara D, Coy M, Makotkine I, Reus VI, Aschbacher K, Bersani FS, Marmar CR, Wolkowitz OM. PMID: 28942957.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    34. Whole-genome DNA methylation status associated with clinical PTSD measures of OIF/OEF veterans. Transl Psychiatry. 2017 07 11; 7(7):e1169. Hammamieh R, Chakraborty N, Gautam A, Muhie S, Yang R, Donohue D, Kumar R, Daigle BJ, Zhang Y, Amara DA, Miller SA, Srinivasan S, Flory J, Yehuda R, Petzold L, Wolkowitz OM, Mellon SH, Hood L, Doyle FJ, Marmar C, Jett M. PMID: 28696412; PMCID: PMC5538114.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    35. Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals-preliminary findings. J Psychosom Res. 2017 08; 99:177-180. Fair B, Mellon SH, Epel ES, Lin J, Révész D, Verhoeven JE, Penninx BW, Reus VI, Rosser R, Hough CM, Mahan L, Burke HM, Blackburn EH, Wolkowitz OM. PMID: 28712425; PMCID: PMC5551436.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    36. Severity of anxiety- but not depression- is associated with oxidative stress in Major Depressive Disorder. J Affect Disord. 2017 09; 219:193-200. Steenkamp LR, Hough CM, Reus VI, Jain FA, Epel ES, James SJ, Morford AE, Mellon SH, Wolkowitz OM, Lindqvist D. PMID: 28564628; PMCID: PMC5550320.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    37. Biological predictors of insulin resistance associated with posttraumatic stress disorder in young military veterans. Psychoneuroendocrinology. 2017 Aug; 82:91-97. Blessing EM, Reus V, Mellon SH, Wolkowitz OM, Flory JD, Bierer L, Lindqvist D, Dhabhar F, Li M, Qian M, Abu-Amara D, Galatzer-Levy I, Yehuda R, Marmar CR. PMID: 28521179.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    38. Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression. Psychoneuroendocrinology. 2017 03; 77:122-130. Hough CM, Lindqvist D, Epel ES, Denis MS, Reus VI, Bersani FS, Rosser R, Mahan L, Burke HM, Wolkowitz OM, Mellon SH. PMID: 28038403; PMCID: PMC5336487.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Oxidative stress, inflammation and treatment response in major depression. Psychoneuroendocrinology. 2017 02; 76:197-205. Lindqvist D, Dhabhar FS, James SJ, Hough CM, Jain FA, Bersani FS, Reus VI, Verhoeven JE, Epel ES, Mahan L, Rosser R, Wolkowitz OM, Mellon SH. PMID: 27960139; PMCID: PMC5272818.
      View in: PubMed   Mentions: 185     Fields:    Translation:Humans
    40. Increased pro-inflammatory milieu in combat related PTSD - A new cohort replication study. Brain Behav Immun. 2017 Jan; 59:260-264. Lindqvist D, Dhabhar FS, Mellon SH, Yehuda R, Grenon SM, Flory JD, Bierer LM, Abu-Amara D, Coy M, Makotkine I, Reus VI, Bersani FS, Marmar CR, Wolkowitz OM. PMID: 27638184.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    41. Cortisol/DHEA ratio and hippocampal volume: A pilot study in major depression and healthy controls. Psychoneuroendocrinology. 2016 10; 72:139-46. Jin RO, Mason S, Mellon SH, Epel ES, Reus VI, Mahan L, Rosser RL, Hough CM, Burke HM, Mueller SG, Wolkowitz OM. PMID: 27428086; PMCID: PMC5203799.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    42. Leukocyte telomere length predicts SSRI response in major depressive disorder: A preliminary report. Mol Neuropsychiatry. 2016 Jul; 2(2):88-96. Hough CM, Bersani FS, Mellon SH, Epel ES, Reus VI, Lindqvist D, Lin J, Mahan L, Rosser R, Burke H, Coetzee J, Nelson JC, Blackburn EH, Wolkowitz OM. PMID: 27429957; PMCID: PMC4943759.
      View in: PubMed   Mentions: 17  
    43. Alterations in leukocyte transcriptional control pathway activity associated with major depressive disorder and antidepressant treatment. Transl Psychiatry. 2016 05 24; 6:e821. Mellon SH, Wolkowitz OM, Schonemann MD, Epel ES, Rosser R, Burke HB, Mahan L, Reus VI, Stamatiou D, Liew CC, Cole SW. PMID: 27219347; PMCID: PMC5070063.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    44. A population of atypical CD56(-)CD16(+) natural killer cells is expanded in PTSD and is associated with symptom severity. Brain Behav Immun. 2016 Aug; 56:264-70. Bersani FS, Wolkowitz OM, Milush JM, Sinclair E, Eppling L, Aschbacher K, Lindqvist D, Yehuda R, Flory J, Bierer LM, Matokine I, Abu-Amara D, Reus VI, Coy M, Hough CM, Marmar CR, Mellon SH. PMID: 27025668.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    45. Neuroscience-informed Auditory Training in Schizophrenia: A Final Report of the Effects on Cognition and Serum Brain-Derived Neurotrophic Factor. Schizophr Res Cogn. 2016 Mar 01; 3:1-7. Fisher M, Mellon SH, Wolkowitz O, Vinogradov S. PMID: 26705516; PMCID: PMC4685735.
      View in: PubMed   Mentions: 29  
    46. Association of dimensional psychological health measures with telomere length in male war veterans. J Affect Disord. 2016 Jan 15; 190:537-542. Bersani FS, Lindqvist D, Mellon SH, Epel ES, Yehuda R, Flory J, Henn-Hasse C, Bierer LM, Makotkine I, Abu-Amara D, Coy M, Reus VI, Lin J, Blackburn EH, Marmar C, Wolkowitz OM. PMID: 26571103.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    47. Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation. Brain Behav Immun. 2016 Feb; 52:153-160. Bersani FS, Wolkowitz OM, Lindqvist D, Yehuda R, Flory J, Bierer LM, Makotine I, Abu-Amara D, Coy M, Reus VI, Epel ES, Marmar C, Mellon SH. PMID: 26515034.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    48. Evidence for disrupted gray matter structural connectivity in posttraumatic stress disorder. Psychiatry Res. 2015 Nov 30; 234(2):194-201. Mueller SG, Ng P, Neylan T, Mackin S, Wolkowitz O, Mellon S, Yan X, Flory J, Yehuda R, Marmar CR, Weiner MW. PMID: 26419357.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    49. Telomerase activation as a possible mechanism of action for psychopharmacological interventions. Drug Discov Today. 2015 Nov; 20(11):1305-9. Bersani FS, Lindqvist D, Mellon SH, Penninx BW, Verhoeven JE, Révész D, Reus VI, Wolkowitz OM. PMID: 26166813.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    50. Mitochondrial DNA copy number is reduced in male combat veterans with PTSD. Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 04; 64:10-7. Bersani FS, Morley C, Lindqvist D, Epel ES, Picard M, Yehuda R, Flory J, Bierer LM, Makotkine I, Abu-Amara D, Coy M, Reus VI, Lin J, Blackburn EH, Marmar C, Wolkowitz OM, Mellon SH. PMID: 26120081.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    51. Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging. Neurosci Biobehav Rev. 2015 Aug; 55:333-64. Lindqvist D, Epel ES, Mellon SH, Penninx BW, Révész D, Verhoeven JE, Reus VI, Lin J, Mahan L, Hough CM, Rosser R, Bersani FS, Blackburn EH, Wolkowitz OM. PMID: 25999120; PMCID: PMC4501875.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansCells
    52. PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression. Psychiatry Res. 2015 Apr 30; 232(1):58-64. Wolkowitz OM, Mellon SH, Lindqvist D, Epel ES, Blackburn EH, Lin J, Reus VI, Burke H, Rosser R, Mahan L, Mackin S, Yang T, Weiner M, Mueller S. PMID: 25773002; PMCID: PMC4404215.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    53. Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings. Psychiatry Res. 2014 Dec 30; 224(3):168-74. Lindqvist D, Mueller S, Mellon SH, Su Y, Epel ES, Reus VI, Rosser R, Mahan L, Mackin RS, Yang TT, Wolkowitz OM. PMID: 25266915; PMCID: PMC4254356.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    54. Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults. J Affect Disord. 2014 Dec; 169:86-90. Chen SH, Epel ES, Mellon SH, Lin J, Reus VI, Rosser R, Kupferman E, Burke H, Mahan L, Blackburn EH, Wolkowitz OM. PMID: 25173430; PMCID: PMC4172492.
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    55. Proinflammatory milieu in combat-related PTSD is independent of depression and early life stress. Brain Behav Immun. 2014 Nov; 42:81-8. Lindqvist D, Wolkowitz OM, Mellon S, Yehuda R, Flory JD, Henn-Haase C, Bierer LM, Abu-Amara D, Coy M, Neylan TC, Makotkine I, Reus VI, Yan X, Taylor NM, Marmar CR, Dhabhar FS. PMID: 24929195.
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    56. Dysregulated relationship of inflammation and oxidative stress in major depression. Brain Behav Immun. 2013 Jul; 31:143-52. Rawdin BJ, Mellon SH, Dhabhar FS, Epel ES, Puterman E, Su Y, Burke HM, Reus VI, Rosser R, Hamilton SP, Nelson JC, Wolkowitz OM. PMID: 23201587; PMCID: PMC3669232.
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    57. A culture system to study oligodendrocyte myelination processes using engineered nanofibers. Nat Methods. 2012 Sep; 9(9):917-22. Lee S, Leach MK, Redmond SA, Chong SY, Mellon SH, Tuck SJ, Feng ZQ, Corey JM, Chan JR. PMID: 22796663; PMCID: PMC3433633.
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    58. Expression of P450c17 in the human fetal nervous system. Endocrinology. 2012 May; 153(5):2494-505. Schonemann MD, Muench MO, Tee MK, Miller WL, Mellon SH. PMID: 22434081; PMCID: PMC3339640.
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    59. Oligogenesis and oligodendrocyte progenitor maturation vary in different brain regions and partially correlate with local angiogenesis after ischemic stroke. Transl Stroke Res. 2011 Sep; 2(3):366-75. Jiang L, Shen F, Degos V, Schonemann M, Pleasure SJ, Mellon SH, Young WL, Su H. PMID: 22022343; PMCID: PMC3196661.
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    60. Serum BDNF levels before treatment predict SSRI response in depression. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1623-30. Wolkowitz OM, Wolf J, Shelly W, Rosser R, Burke HM, Lerner GK, Reus VI, Nelson JC, Epel ES, Mellon SH. PMID: 21749907; PMCID: PMC3159044.
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    61. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings. PLoS One. 2011 Mar 23; 6(3):e17837. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Dhabhar FS, Su Y, Reus VI, Rosser R, Burke HM, Kupferman E, Compagnone M, Nelson JC, Blackburn EH. PMID: 21448457; PMCID: PMC3063175.
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    62. Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response. Mol Psychiatry. 2012 Feb; 17(2):164-72. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Reus VI, Rosser R, Burke H, Compagnone M, Nelson JC, Dhabhar FS, Blackburn EH. PMID: 21242992; PMCID: PMC3130817.
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    63. Of sound mind and body: depression, disease, and accelerated aging. Dialogues Clin Neurosci. 2011; 13(1):25-39. Wolkowitz OM, Reus VI, Mellon SH. PMID: 21485744; PMCID: PMC3181963.
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    64. Estrogen receptor beta-selective agonists stimulate calcium oscillations in human and mouse embryonic stem cell-derived neurons. PLoS One. 2010 Jul 27; 5(7):e11791. Zhang L, Blackman BE, Schonemann MD, Zogovic-Kapsalis T, Pan X, Tagliaferri M, Harris HA, Cohen I, Pera RA, Mellon SH, Weiner RI, Leitman DC. PMID: 20668547; PMCID: PMC2910705.
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    65. Serum brain-derived neurotrophic factor predicts responses to escitalopram in chronic posttraumatic stress disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 01; 34(7):1279-84. Berger W, Mehra A, Lenoci M, Metzler TJ, Otte C, Tarasovsky G, Mellon SH, Wolkowitz OM, Marmar CR, Neylan TC. PMID: 20643177; PMCID: PMC2939182.
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    66. Depression gets old fast: do stress and depression accelerate cell aging? Depress Anxiety. 2010 Apr; 27(4):327-38. Wolkowitz OM, Epel ES, Reus VI, Mellon SH. PMID: 20376837.
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    67. Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance. J Immunol Methods. 2010 Jan 31; 352(1-2):71-80. Lin J, Epel E, Cheon J, Kroenke C, Sinclair E, Bigos M, Wolkowitz O, Mellon S, Blackburn E. PMID: 19837074; PMCID: PMC3280689.
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    68. Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression. J Psychiatr Res. 2009 Jul; 43(11):962-9. Dhabhar FS, Burke HM, Epel ES, Mellon SH, Rosser R, Reus VI, Wolkowitz OM. PMID: 19552919.
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    69. Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia? Biol Psychiatry. 2009 Sep 15; 66(6):549-53. Vinogradov S, Fisher M, Holland C, Shelly W, Wolkowitz O, Mellon SH. PMID: 19368899; PMCID: PMC4691262.
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    70. Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS). Front Neuroendocrinol. 2009 Jan; 30(1):65-91. Maninger N, Wolkowitz OM, Reus VI, Epel ES, Mellon SH. PMID: 19063914; PMCID: PMC2725024.
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    71. Regulation of P450c17 expression in the early embryo depends on GATA factors. Endocrinology. 2009 Feb; 150(2):946-56. Shi Y, Schonemann MD, Mellon SH. PMID: 18832096; PMCID: PMC2646537.
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    72. Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone. J Cell Mol Med. 2009 Sep; 13(9B):3786-96. Zampieri S, Mellon SH, Butters TD, Nevyjel M, Covey DF, Bembi B, Dardis A. PMID: 18774957; PMCID: PMC2832077.
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    73. When blue turns to grey: do stress and depression accelerate cell aging? World J Biol Psychiatry. 2008; 9(1):2-5. Wolkowitz OM, Epel ES, Mellon S. PMID: 18273736.
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    74. Neurosteroid regulation of central nervous system development. Pharmacol Ther. 2007 Oct; 116(1):107-24. Mellon SH. PMID: 17651807; PMCID: PMC2386997.
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    75. Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease. Brain Res Rev. 2008 Mar; 57(2):410-20. Mellon SH, Gong W, Schonemann MD. PMID: 17629950; PMCID: PMC2323675.
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    76. Translin coactivates steroidogenic factor-1-stimulated transcription. Mol Endocrinol. 2007 Jan; 21(1):89-105. Mellon SH, Bair SR, Depoix C, Vigne JL, Hecht NB, Brake PB. PMID: 17053042.
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    77. Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease. Proc Natl Acad Sci U S A. 2006 Sep 12; 103(37):13807-12. Langmade SJ, Gale SE, Frolov A, Mohri I, Suzuki K, Mellon SH, Walkley SU, Covey DF, Schaffer JE, Ory DS. PMID: 16940355; PMCID: PMC1564205.
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    78. DNA sequence-dependent regulation of SF-1-mediated transcription. DNA Cell Biol. 2005 Mar; 24(3):148-60. Brake PB, Bair SR, Mellon SH. PMID: 15767781.
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    79. Niemann pick type C disease as a model for defects in neurosteroidogenesis. Endocr Res. 2004 Nov; 30(4):727-35. Mellon S, Gong W, Griffin LD. PMID: 15666818.
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    80. Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone. Nat Med. 2004 Jul; 10(7):704-11. Griffin LD, Gong W, Verot L, Mellon SH. PMID: 15208706.
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    81. Deletion of the mouse P450c17 gene causes early embryonic lethality. Mol Cell Biol. 2004 Jun; 24(12):5383-90. Bair SR, Mellon SH. PMID: 15169901; PMCID: PMC419874.
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    82. The Endocrine Society Ethics Advisory Committee: ethical aspects of conflicts of interests, October 2003. Endocrinology. 2004 Jun; 145(6):3032-41. Komesaroff PA, Bach MA, Danoff A, Grumbach MM, Kaplan S, Lakoski JM, Leitman D, Mellon S, Underwood LE, Leupen S, Endocrine Society Ethics Advisory Committee. PMID: 15140839.
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    83. Molecular mechanism of suppression of testicular steroidogenesis by proinflammatory cytokine tumor necrosis factor alpha. Mol Cell Biol. 2004 Apr; 24(7):2593-604. Hong CY, Park JH, Ahn RS, Im SY, Choi HS, Soh J, Mellon SH, Lee K. PMID: 15024051; PMCID: PMC371106.
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    84. Transcriptional regulation of P450scc gene expression in the embryonic rodent nervous system. Endocrinology. 2004 Feb; 145(2):901-12. Hammer F, Compagnone NA, Vigne JL, Bair SR, Mellon SH. PMID: 14576192.
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    85. Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. J Biol Chem. 2003 Jan 31; 278(5):2837-44. Pandey AV, Mellon SH, Miller WL. PMID: 12444089.
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    86. Synthesis, regulation, and function of neurosteroids. Endocr Res. 2002 Nov; 28(4):463. Mellon SH, Griffin LD. PMID: 12530649.
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    87. Dietary phosphorus transcriptionally regulates 25-hydroxyvitamin D-1alpha-hydroxylase gene expression in the proximal renal tubule. Endocrinology. 2002 Feb; 143(2):587-95. Zhang MY, Wang X, Wang JT, Compagnone NA, Mellon SH, Olson JL, Tenenhouse HS, Miller WL, Portale AA. PMID: 11796514.
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    88. Neurosteroids: biochemistry and clinical significance. Trends Endocrinol Metab. 2002 Jan-Feb; 13(1):35-43. Mellon SH, Griffin LD. PMID: 11750861.
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    89. Biosynthesis of the neurosteroid 3 alpha-hydroxy-4-pregnen-20-one (3 alpha hp), a specific inhibitor of FSH release. Endocrinology. 2001 Nov; 142(11):4617-22. Griffin LD, Mellon SH. PMID: 11606426.
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    90. Biosynthesis and action of neurosteroids. Brain Res Brain Res Rev. 2001 Nov; 37(1-3):3-12. Mellon SH, Griffin LD, Compagnone NA. PMID: 11744070.
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    91. Developmental gonadal expression of the transcription factor SET and its target gene, P450c17 (17alpha-hydroxylase/c17,20 lyase). DNA Cell Biol. 2001 Oct; 20(10):613-24. Zhang P, Compagnone NA, Fiore C, Vigne JL, Culp P, Musci TJ, Mellon SH. PMID: 11749720.
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    92. Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy. Endocrinology. 2001 May; 142(5):1770-7. Fujii E, Mellon SH. PMID: 11316740.
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    93. Modulation of steroidogenesis by selenium in a novel adrenal cell line developed using targeted tumorigenesis. Biofactors. 2001; 14(1-4):229-38. Chanoine JP, Compagnone NA, Wong AC, Mellon SH. PMID: 11568460.
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    94. Current perspectives on the role of neurosteroids in PMS and depression. Int Rev Neurobiol. 2001; 46:479-92. Griffin LD, Conrad SC, Mellon SH. PMID: 11599311.
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    95. Biosynthesis of neurosteroids and regulation of their synthesis. Int Rev Neurobiol. 2001; 46:33-78. Mellon SH, Vaudry H. PMID: 11599305.
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    96. Opposing early inhibitory and late stimulatory effects of insulin-like growth factor-I on myogenin gene transcription. J Cell Biochem. 2000 Jun 12; 78(4):617-26. Adi S, Cheng ZQ, Zhang PL, Wu NY, Mellon SH, Rosenthal SM. PMID: 10861859.
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    97. Novel role for the nuclear phosphoprotein SET in transcriptional activation of P450c17 and initiation of neurosteroidogenesis. Mol Endocrinol. 2000 Jun; 14(6):875-88. Compagnone NA, Zhang P, Vigne JL, Mellon SH. PMID: 10847589.
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    98. Autocrine and paracrine Müllerian inhibiting substance hormone signaling in reproduction. Recent Prog Horm Res. 2000; 55:53-67; discussion 67-8. Ingraham HA, Hirokawa Y, Roberts LM, Mellon SH, McGee E, Nachtigal MW, Visser JA. PMID: 11036933.
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    99. Neurosteroids: biosynthesis and function of these novel neuromodulators. Front Neuroendocrinol. 2000 Jan; 21(1):1-56. Compagnone NA, Mellon SH. PMID: 10662535.
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    100. Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. Proc Natl Acad Sci U S A. 1999 Nov 09; 96(23):13512-7. Griffin LD, Mellon SH. PMID: 10557352; PMCID: PMC23979.
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    101. Ku autoimmune antigen is involved in placental regulation of rat P450c17 gene transcription. DNA Cell Biol. 1999 Mar; 18(3):197-208. Zhang P, Hammer F, Bair S, Wang J, Reeves WH, Mellon SH. PMID: 10098601.
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    102. Orphan receptors, proto-oncogenes and other nuclear factors regulate P450C17 gene transcription. Endocr Res. 1998 Aug-Nov; 24(3-4):505-13. Mellon SH, Compagnone NA, Zhang P. PMID: 9888531.
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    103. 25-Hydroxycholesterol is not a ligand for the orphan nuclear receptor steroidogenic factor-1 (SF-1). Endocrinology. 1998 Jun; 139(6):3026-9. Mellon SH, Bair SR. PMID: 9607816.
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    104. Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4678-83. Compagnone NA, Mellon SH. PMID: 9539798; PMCID: PMC22550.
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    105. Polyribonucleotide phosphorylase is a double-stranded DNA-binding protein. DNA Cell Biol. 1998 Feb; 17(2):169-75. Zhang P, Vigne JL, Mellon SH. PMID: 9502433.
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    106. Expression of steroid sulfatase during embryogenesis. Endocrinology. 1997 Nov; 138(11):4768-73. Compagnone NA, Salido E, Shapiro LJ, Mellon SH. PMID: 9348204.
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    107. Multiple orphan nuclear receptors converge to regulate rat P450c17 gene transcription: novel mechanisms for orphan nuclear receptor action. Mol Endocrinol. 1997 Jun; 11(7):891-904. Zhang P, Mellon SH. PMID: 9178749.
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    108. Characterization of adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice. Steroids. 1997 Feb; 62(2):238-43. Compagnone NA, Bair SR, Mellon SH. PMID: 9055383.
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    109. The testis and the adrenal are (transcriptionally) the same. Steroids. 1997 Jan; 62(1):46-52. Mellon SH, Zhang P. PMID: 9029714.
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    110. Enzymatic properties of transplanted glomerulosa cells. World J Surg. 1996 Sep; 20(7):933-8; discussion 938-9. Scheumann GF, Heitmann P, Teebken OE, Mössinger E, Mellon SH, Pichlmayr R. PMID: 8678974.
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    111. Cytochrome P450 17 alpha-hydroxylase gene expression in differentiating rat trophoblast cells. J Endocrinol. 1996 Jul; 150(1):161-8. Yamamoto T, Chapman BM, Johnson DC, Givens CR, Mellon SH, Soares MJ. PMID: 8708557.
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    112. Expression of the gene for cytochrome P-450 17 alpha-hydroxylase/C17-20 lyase (CYP17) in porcine Leydig cells: identification of a DNA sequence that mediates cAMP response. Biochim Biophys Acta. 1996 Jun 03; 1307(1):73-82. Zhang P, Han XG, Mellon SH, Hall PF. PMID: 8652670.
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    113. The orphan nuclear receptor steroidogenic factor-1 regulates the cyclic adenosine 3',5'-monophosphate-mediated transcriptional activation of rat cytochrome P450c17 (17 alpha-hydroxylase/c17-20 lyase). Mol Endocrinol. 1996 Feb; 10(2):147-58. Zhang P, Mellon SH. PMID: 8825555.
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    114. Transcriptional regulation of P450scc gene expression in neural and steroidogenic cells: implications for regulation of neurosteroidogenesis. Mol Endocrinol. 1995 Nov; 9(11):1571-82. Zhang P, Rodriguez H, Mellon SH. PMID: 8584034.
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    115. Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system. Endocrinology. 1995 Nov; 136(11):5212-23. Compagnone NA, Bulfone A, Rubenstein JL, Mellon SH. PMID: 7588260.
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    116. Targeted ablation of pituitary pre-proopiomelanocortin cells by herpes simplex virus-1 thymidine kinase differentially regulates mRNAs encoding the adrenocorticotropin receptor and aldosterone synthase in the mouse adrenal gland. Mol Endocrinol. 1995 Aug; 9(8):1005-16. Allen RG, Carey C, Parker JD, Mortrud MT, Mellon SH, Low MJ. PMID: 7476975.
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    117. Molecular variants in the P450c11AS gene as determinants of aldosterone synthase activity in the Dahl rat model of hypertension. J Biol Chem. 1995 Jul 14; 270(28):16555-60. Cover CM, Wang JM, St Lezin E, Kurtz TW, Mellon SH. PMID: 7622461.
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    118. Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27. J Hypertens. 1995 Jun; 13(6):637-45. Djavidani B, Sander M, Kreutz R, Zeh K, Bader M, Mellon SH, Vecsei P, Peters J, Ganten D. PMID: 7594421.
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    119. Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis. Endocrinology. 1995 Jun; 136(6):2689-96. Compagnone NA, Bulfone A, Rubenstein JL, Mellon SH. PMID: 7750493.
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    120. Artificial mutations in P450c11AS (aldosterone synthase) can increase enzymatic activity: a model for low-renin hypertension? J Clin Endocrinol Metab. 1995 Mar; 80(3):1040-3. Fardella CE, Rodriguez H, Hum DW, Mellon SH, Miller WL. PMID: 7883820.
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    121. P450c11B3 mRNA, transcribed from a third P450c11 gene, is expressed in a tissue-specific, developmentally, and hormonally regulated fashion in the rodent adrenal and encodes a protein with both 11-hydroxylase and 18-hydroxylase activities. J Biol Chem. 1995 Jan 27; 270(4):1643-9. Mellon SH, Bair SR, Monis H. PMID: 7829497.
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    122. Prenatal diagnosis of congenital lipoid adrenal hyperplasia. J Clin Endocrinol Metab. 1995 Jan; 80(1):200-5. Saenger P, Klonari Z, Black SM, Compagnone N, Mellon SH, Fleischer A, Abrams CA, Shackelton CH, Miller WL. PMID: 7829612.
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    123. Rodent models for studying steroids and hypertension: from fetal development to cells in culture. Steroids. 1995 Jan; 60(1):59-64. Mellon SH, Compagnone N, Sander M, Cover C, Ganten D, Djavidani B. PMID: 7792817.
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    124. Transcriptional regulation of rat cytochrome P450c17 expression in mouse Leydig MA-10 and adrenal Y-1 cells: identification of a single protein that mediates both basal and cAMP-induced activities. DNA Cell Biol. 1994 Nov; 13(11):1087-98. Givens CR, Zhang P, Bair SR, Mellon SH. PMID: 7702752.
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    125. Neurosteroids: biochemistry, modes of action, and clinical relevance. J Clin Endocrinol Metab. 1994 May; 78(5):1003-8. Mellon SH. PMID: 8175951.
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    126. Role of adrenal renin in the regulation of adrenal steroidogenesis by corticotropin. Proc Natl Acad Sci U S A. 1994 Jan 04; 91(1):148-52. Sander M, Ganten D, Mellon SH. PMID: 8278356; PMCID: PMC42903.
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    127. Steroidogenic adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice. Mol Endocrinol. 1994 Jan; 8(1):97-108. Mellon SH, Miller WL, Bair SR, Moore CC, Vigne JL, Weiner RI. PMID: 8152434.
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    128. Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain. Brain Res. 1993 Dec 03; 629(2):283-92. Mellon SH, Deschepper CF. PMID: 8111631.
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    129. Structure and function of the hepatic form of 11 beta-hydroxysteroid dehydrogenase in the squirrel monkey, an animal model of glucocorticoid resistance. Endocrinology. 1993 Jul; 133(1):368-75. Moore CC, Mellon SH, Murai J, Siiteri PK, Miller WL. PMID: 8319583.
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    130. Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B. J Cell Biol. 1993 Jul; 122(1):265-78. Bristow J, Tee MK, Gitelman SE, Mellon SH, Miller WL. PMID: 7686164; PMCID: PMC2119596.
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    131. Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland. J Clin Endocrinol Metab. 1993 Apr; 76(4):968-76. Mesiano S, Mellon SH, Jaffe RB. PMID: 8473412.
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    132. Basic fibroblast growth factor expression is regulated by corticotropin in the human fetal adrenal: a model for adrenal growth regulation. Proc Natl Acad Sci U S A. 1991 Jun 15; 88(12):5428-32. Mesiano S, Mellon SH, Gospodarowicz D, Di Blasio AM, Jaffe RB. PMID: 1711231; PMCID: PMC51886.
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    133. Expression and regulation of adrenodoxin and P450scc mRNA in rodent tissues. DNA Cell Biol. 1991 Jun; 10(5):339-47. Mellon SH, Kushner JA, Vaisse C. PMID: 1863358.
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    134. Zone-specific regulation of two messenger RNAs for P450c11 in the adrenals of pregnant and nonpregnant rats. Proc Natl Acad Sci U S A. 1991 Jun 01; 88(11):4731-5. Malee MP, Mellon SH. PMID: 2052554; PMCID: PMC51740.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    135. Human proopiomelanocortin-(79-96), a proposed androgen stimulatory hormone, does not affect steroidogenesis in cultured human fetal adrenal cells. J Clin Endocrinol Metab. 1991 Jan; 72(1):19-22. Mellon SH, Shively JE, Miller WL. PMID: 1846003.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    136. Tissue-specific, cyclic adenosine 3',5'-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells. Mol Endocrinol. 1990 Dec; 4(12):1972-9. Brentano ST, Picado-Leonard J, Mellon SH, Moore CC, Miller WL. PMID: 1964490.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    137. Effect of extracellular matrix on prolactin secretion and mRNA accumulation in GH3 cells. DNA Cell Biol. 1990 Jun; 9(5):369-75. Elias KA, Weiner RI, Mellon SH. PMID: 2115339.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    138. Extraadrenal steroid 21-hydroxylation is not mediated by P450c21. J Clin Invest. 1989 Nov; 84(5):1497-502. Mellon SH, Miller WL. PMID: 2808702; PMCID: PMC304014.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    139. cAMP regulates P450scc gene expression by a cycloheximide-insensitive mechanism in cultured mouse Leydig MA-10 cells. Proc Natl Acad Sci U S A. 1989 Oct; 86(20):7775-9. Mellon SH, Vaisse C. PMID: 2554289; PMCID: PMC298153.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    140. Cell-specific expression of transfected brain identifier repetitive DNAs. Nucleic Acids Res. 1988 May 11; 16(9):3963-76. Mellon SH, Baxter JD, Gutierrez-Hartmann A. PMID: 2453842; PMCID: PMC336568.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    141. In situ hybridization identifies renin mRNA in the rat corpus luteum. Gynecol Endocrinol. 1987 Sep; 1(3):227-33. Lightman A, Deschepper CF, Mellon SH, Ganong WF, Naftolin F. PMID: 3332536.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    142. Interaction of a tissue-specific factor with an essential rat growth hormone gene promoter element. Mol Cell Biol. 1987 Mar; 7(3):1193-7. West BL, Catanzaro DF, Mellon SH, Cattini PA, Baxter JD, Reudelhuber TL. PMID: 3561414; PMCID: PMC365192.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    143. Analysis by immunocytochemistry and in situ hybridization of renin and its mRNA in kidney, testis, adrenal, and pituitary of the rat. Proc Natl Acad Sci U S A. 1986 Oct; 83(19):7552-6. Deschepper CF, Mellon SH, Cumin F, Baxter JD, Ganong WF. PMID: 3532116; PMCID: PMC386757.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    144. An approach to the molecular biology of congenital adrenal hyperplasia. Ann N Y Acad Sci. 1985; 458:238-51. Chung BC, Matteson KJ, Morin JE, Mellon SH, Miller WL. PMID: 3879125.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    145. Expression and hormonal regulation of the rat growth hormone gene in transfected mouse L cells. DNA. 1984; 3(2):147-55. Karin M, Eberhardt NL, Mellon SH, Malich N, Richards RI, Slater EP, Barta A, Martial JA, Baxter JD, Cathala G. PMID: 6723496.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    146. Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells. J Biol Chem. 1982 Oct 10; 257(19):11627-32. Spindler SR, Mellon SH, Baxter JD. PMID: 7118899.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
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