Rachel Rutishauser, MD, PhD

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone628-206-8188
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    Collapse Biography 
    Collapse Education and Training
    Harvard UniversityB.A.2003Biology
    Yale UniversityPh.D.2010Immunobiology
    Yale UniversityM.D.2011School of Medicine
    University of California, San FranciscoResidency2014Internal Medicine
    University of California, San FranciscoFellowship2018Infectious Disease
    Collapse Awards and Honors
    Yale University2011The MD/PhD Award
    Yale University2011Norma Bailey Berniker Prize
    UCSF2015SFGH Department of Medicine Clinical Fellow Award
    UCSF2015UCSF Infectious Diseases Division Clinical Fellow Award
    IDSA2015IDWeek Trainee Travel Award
    UCSF2016AIDS Research Institute Clinical Fellow
    HVTN2017HVTN Translational Early Stage Investigator Conference Travel Award
    UCSF2017CFAR Early Career Award for Excellence in Basic Research
    HVTN2018HVTN Translational Early Stage Investigator Conference Travel Award
    CROI2018CROI New Investigator Scholarship
    CROI2019CROI New Investigator Scholarship

    Collapse Overview 
    Collapse Overview
    I am an infectious disease-trained Associate Professor of Medicine in the Division of Experimental Medicine at the University of California, San Francisco. My laboratory focuses on understanding the mechanisms that promote the formation of effective and durable CD8+ T cell immunity to viral pathogens (e.g., HIV, SARS-CoV-2) and vaccination at different stages of human development.

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. In vivo killing of primary HIV-infected cells by peripheral-injected early memory-enriched anti-HIV duoCAR T cells. JCI Insight. 2022 11 08; 7(21). Anthony-Gonda K, Ray A, Su H, Wang Y, Xiong Y, Lee D, Block A, Chilunda V, Weiselberg J, Zemelko L, Wang YY, Kleinsorge-Block S, Reese JS, de Lima M, Ochsenbauer C, Kappes JC, Dimitrov DS, Orentas R, Deeks SG, Rutishauser RL, Berman JW, Goldstein H, Dropulic B. PMID: 36345941; PMCID: PMC9675454.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection. AIDS. 2022 10 01; 36(12):F7-F16. Peluso MJ, Spinelli MA, Deveau TM, Forman CA, Munter SE, Mathur S, Tang AF, Lu S, Goldberg SA, Arreguin MI, Hoh R, Tai V, Chen JY, Martinez EO, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Sette A, Weiskopf D, Kumar N, Lynch KL, Hunt PW, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Glidden DV, Gandhi M, Deeks SG, Rutishauser RL, Henrich TJ. PMID: 35866847; PMCID: PMC9444925.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    3. CD8 + T-cell responses in HIV controllers: potential implications for novel HIV remission strategies. Curr Opin HIV AIDS. 2022 09 01; 17(5):315-324. Rutishauser RL, Trautmann L. PMID: 35777930; PMCID: PMC9378446.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. A cytotoxic-skewed immune set point predicts low neutralizing antibody levels after Zika virus infection. Cell Rep. 2022 05 17; 39(7):110815. McCarthy EE, Odorizzi PM, Lutz E, Smullin CP, Tenvooren I, Stone M, Simmons G, Hunt PW, Feeney ME, Norris PJ, Busch MP, Spitzer MH, Rutishauser RL. PMID: 35584677; PMCID: PMC9151348.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    5. Pneumonia surveillance with culture-independent metatranscriptomics in HIV-positive adults in Uganda: a cross-sectional study. Lancet Microbe. 2022 05; 3(5):e357-e365. Spottiswoode N, Bloomstein JD, Caldera S, Sessolo A, McCauley K, Byanyima P, Zawedde J, Kalantar K, Kaswabuli S, Rutishauser RL, Lieng MK, Davis JL, Moore J, Jan A, Iwai S, Shenoy M, Sanyu I, DeRisi JL, Lynch SV, Worodria W, Huang L, Langelier CR. PMID: 35544096.
      View in: PubMed   Mentions: Translation:HumansCells
    6. Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement. Open Forum Infect Dis. 2022 Feb; 9(2):ofab640. Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger MA, Assenzio MT, Yuan Y, Krone MR, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Scheffler AW, Hsue PY, Henrich TJ, Deeks SG, Martin JN. PMID: 35106317; PMCID: PMC8755302.
      View in: PubMed   Mentions: 18  
    7. Impact of Anti-PD-1 and Anti-CTLA-4 on the Human Immunodeficiency Virus (HIV) Reservoir in People Living With HIV With Cancer on Antiretroviral Therapy: The AIDS Malignancy Consortium 095 Study. Clin Infect Dis. 2021 10 05; 73(7):e1973-e1981. Rasmussen TA, Rajdev L, Rhodes A, Dantanarayana A, Tennakoon S, Chea S, Spelman T, Lensing S, Rutishauser R, Bakkour S, Busch M, Siliciano JD, Siliciano RF, Einstein MH, Dittmer DP, Chiao E, Deeks SG, Durand C, Lewin SR. PMID: 33677480; PMCID: PMC8492152.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsCTClinical Trials
    8. Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms. Cell Rep. 2021 08 10; 36(6):109518. Peluso MJ, Deitchman AN, Torres L, Iyer NS, Munter SE, Nixon CC, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman EA, Spinelli MA, Gandhi M, Trinh L, Wrin T, Petropoulos CJ, Aweeka FT, Rodriguez-Barraquer I, Kelly JD, Martin JN, Deeks SG, Greenhouse B, Rutishauser RL, Henrich TJ. PMID: 34358460; PMCID: PMC8342976.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    9. SARS-CoV-2 Vaccination in the Context of Ongoing HIV Cure-Related Research Studies. J Acquir Immune Defic Syndr. 2021 08 01; 87(4):e232-e233. Peluso MJ, Dee L, Taylor J, Campbell DM, Ehm A, Agosto-Rosario M, Shao S, Williams MC, Hoh R, Rutishauser RL, Deeks SG, Sauceda JA, Dub? K. PMID: 33852502; PMCID: PMC8217209.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    10. SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay. Sci Adv. 2021 Jul; 7(31). Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Donatelli J, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petropoulos CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B. PMID: 34330709; PMCID: PMC8324059.
      View in: PubMed   Mentions: 51     Fields:    
    11. Discordant Virus-Specific Antibody Levels, Antibody Neutralization Capacity, and T-cell Responses Following 3 Doses of SARS-CoV-2 Vaccination in a Patient With Connective Tissue Disease. Open Forum Infect Dis. 2021 Aug; 8(8):ofab393. Peluso MJ, Munter SE, Lynch KL, Yun C, Torres L, Iyer NS, Donatelli J, Ryan L, Deitchman AN, Deeks SG, Rutishauser RL, Henrich TJ. PMID: 34395717; PMCID: PMC8344490.
      View in: PubMed   Mentions: 3  
    12. Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19. medRxiv. 2021 Mar 12. Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Bautista JA, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger M, Assenzio M, Yuan Y, Krone M, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Hsue PY, Henrich TJ, Deeks SG, Martin JN. PMID: 33758895; PMCID: PMC7987054.
      View in: PubMed   Mentions:
    13. Long-Term SARS-CoV-2-Specific Immune and Inflammatory Responses Across a Clinically Diverse Cohort of Individuals Recovering from COVID-19. medRxiv. 2021 Mar 01. Peluso MJ, Deitchman AN, Torres L, Iyer NS, Nixon CC, Munter SE, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman E, Spinelli MA, Gandhi M, Trinh L, Wrin T, Petropoulos CJ, Aweeka FT, Rodriguez-Barraquer I, Kelly JD, Martin JN, Deeks SG, Greenhouse B, Rutishauser RL, Henrich TJ. PMID: 33688685; PMCID: PMC7941662.
      View in: PubMed   Mentions: 1  
    14. Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations. Cells. 2021 02 13; 10(2). Sun B, Tang N, Peluso MJ, Iyer NS, Torres L, Donatelli JL, Munter SE, Nixon CC, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Pulliam L. PMID: 33668514; PMCID: PMC7918597.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    15. TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. JCI Insight. 2021 02 08; 6(3). Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin C, Matus-Nicodemos R, Hoh R, Krone M, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek DC, Brenchley JM, S?kaly RP, Pillai SK, Marson A, Deeks SG, McCune JM, Hunt PW. PMID: 33351785; PMCID: PMC7934879.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    16. Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells. Cell Rep. 2021 01 05; 34(1):108573. Bunis DG, Bronevetsky Y, Krow-Lucal E, Bhakta NR, Kim CC, Nerella S, Jones N, Mendoza VF, Bryson YJ, Gern JE, Rutishauser RL, Ye CJ, Sirota M, McCune JM, Burt TD. PMID: 33406429.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    17. Everolimus, an mTORC1/2 inhibitor, in ART-suppressed individuals who received solid organ transplantation: A prospective study. Am J Transplant. 2021 05; 21(5):1765-1779. Henrich TJ, Schreiner C, Cameron C, Hogan LE, Richardson B, Rutishauser RL, Deitchman AN, Chu S, Rogers R, Thanh C, Gibson EA, Zarinsefat A, Bakkour S, Aweeka F, Busch MP, Liegler T, Baker C, Milush J, Deeks SG, Stock PG. PMID: 32780519; PMCID: PMC9177122.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    18. Clinical Utility of Universal Broad-Range Polymerase Chain Reaction Amplicon Sequencing for Pathogen Identification: A Retrospective Cohort Study. Clin Infect Dis. 2020 09 12; 71(6):1554-1557. Kerkhoff AD, Rutishauser RL, Miller S, Babik JM. PMID: 31907545; PMCID: PMC7486847.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    19. Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol. 2020 05; 21(5):578-587. Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B. PMID: 32231298; PMCID: PMC7183435.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    20. A collaborative, multidisciplinary approach to HIV transmission risk mitigation during analytic treatment interruption. J Virus Erad. 2020 Feb 20; 6(1):34-37. Peluso MJ, Dee L, Campbell D, Taylor J, Hoh R, Rutishauser RL, Sauceda J, Deeks SG, Dub? K. PMID: 32175090; PMCID: PMC7043899.
      View in: PubMed   Mentions: 17  
    21. OP 4.2 Characterising ‘exceptional’ control among HIV elite controllers. Journal of virus eradication. 2019 Dec 1; 5:31. Peluso PM, Burbelo BP, Kumar KS, Munter MS, Hoh HR, Lee LS, Hunt HP, Rutishauser RR, Henrich HT, Deeks DS. .
      View in: Publisher Site   Mentions:
    22. Some Aspects of CD8+ T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):211-219. Deguit CDT, Hough M, Hoh R, Krone M, Pilcher CD, Martin JN, Deeks SG, McCune JM, Hunt PW, Rutishauser RL. PMID: 31513075; PMCID: PMC6746248.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Rapid development of HIV elite control in a patient with acute infection. BMC Infect Dis. 2019 Sep 18; 19(1):815. Morley D, Lambert JS, Hogan LE, De Gascun C, Redmond N, Rutishauser RL, Thanh C, Gibson EA, Hobbs K, Bakkour S, Busch MP, Farrell J, McGetrick P, Henrich TJ. PMID: 31533639; PMCID: PMC6749690.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    24. Inconsistent HIV reservoir dynamics and immune responses following anti-PD-1 therapy in cancer patients with HIV infection. Ann Oncol. 2018 10 01; 29(10):2141-2142. Scully EP, Rutishauser RL, Simoneau CR, Delagrèverie H, Euler Z, Thanh C, Li JZ, Hartig H, Bakkour S, Busch M, Alter G, Marty FM, Wang CC, Deeks SG, Lorch J, Henrich TJ. PMID: 30032204; PMCID: PMC6225895.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    25. HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study. PLoS Med. 2017 Nov; 14(11):e1002417. Henrich TJ, Hatano H, Bacon O, Hogan LE, Rutishauser R, Hill A, Kearney MF, Anderson EM, Buchbinder SP, Cohen SE, Abdel-Mohsen M, Pohlmeyer CW, Fromentin R, Hoh R, Liu AY, McCune JM, Spindler J, Metcalf-Pate K, Hobbs KS, Thanh C, Gibson EA, Kuritzkes DR, Siliciano RF, Price RW, Richman DD, Chomont N, Siliciano JD, Mellors JW, Yukl SA, Blankson JN, Liegler T, Deeks SG. PMID: 29112956; PMCID: PMC5675377.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansCellsPHPublic Health
    26. Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals. Gut Microbes. 2017 09 03; 8(5):440-450. Vujkovic-Cvijin I, Rutishauser RL, Pao M, Hunt PW, Lynch SV, McCune JM, Somsouk M. PMID: 28541799; PMCID: PMC5628639.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    27. Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression. AIDS Res Hum Retroviruses. 2017 07; 33(7):658-667. Rutishauser RL, Hartogensis W, Deguit CD, Krone M, Hoh R, Hecht FM, Pilcher CD, Bacchetti P, Deeks SG, Hunt PW, McCune JM. PMID: 28335609; PMCID: PMC5512309.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsPHPublic Health
    28. Disseminated Acanthamoeba infection in a heart transplant recipient treated successfully with a miltefosine-containing regimen: Case report and review of the literature. Transpl Infect Dis. 2017 Apr; 19(2). Brondfield MN, Reid MJ, Rutishauser RL, Cope JR, Tang J, Ritter JM, Matanock A, Ali I, Doernberg SB, Hilts-Horeczko A, DeMarco T, Klein L, Babik JM. PMID: 28067969; PMCID: PMC5510642.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    29. Antimicrobial Resistance: A Call to Action! Clin Infect Dis. 2017 01 01; 64(1):106-107. Brown L, Langelier C, Reid MJ, Rutishauser RL, Strnad L. PMID: 27794024; PMCID: PMC5159605.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Broad-range PCR for early diagnosis of nosocomial Enterococcus gallinarum meningitis. Infect Dis (Lond). 2016 Aug; 48(8):640-2. Su PY, Miller S, Rutishauser RL, Babik J. PMID: 27097275.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    31. Think global, act local: chronic dysuria and sterile pyuria in an Eritrean-American woman. BMJ Case Rep. 2014 Feb 11; 2014. Rutishauser RL, Langelier C, Baxi SM, Hanks D, Chin-Hong P. PMID: 24518390; PMCID: PMC3926384.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection. Immunity. 2011 Oct 28; 35(4):633-46. Marshall HD, Chandele A, Jung YW, Meng H, Poholek AC, Parish IA, Rutishauser R, Cui W, Kleinstein SH, Craft J, Kaech SM. PMID: 22018471; PMCID: PMC3444169.
      View in: PubMed   Mentions: 181     Fields:    Translation:AnimalsCells
    33. Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection. J Immunol. 2010 Nov 01; 185(9):5315-25. Jung YW, Rutishauser RL, Joshi NS, Haberman AM, Kaech SM. PMID: 20921525; PMCID: PMC4267692.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    34. Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation. Immunol Rev. 2010 May; 235(1):219-33. Rutishauser RL, Kaech SM. PMID: 20536566.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    35. Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity. 2009 Aug 21; 31(2):296-308. Rutishauser RL, Martins GA, Kalachikov S, Chandele A, Parish IA, Meffre E, Jacob J, Calame K, Kaech SM. PMID: 19664941; PMCID: PMC2783637.
      View in: PubMed   Mentions: 325     Fields:    Translation:AnimalsCells
    36. Long-term consequences of agonistic interactions between socially naive juvenile American lobsters (Homarus americanus). Biol Bull. 2004 Dec; 207(3):183-7. Rutishauser RL, Basu AC, Cromarty SI, Kravitz EA. PMID: 15616347.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
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