Anthony Wong, MD, PhD

Title(s)Assistant Professor, Radiation Oncology
SchoolSchool of Medicine
Address1600 Divisadero Street
ORCID ORCID Icon0000-0002-9288-061X Additional info
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    Collapse Education and Training
    Yale University, New Haven, CTBS05/2004Molecular Biophysics and Biochemistry
    Albert Einstein College of Medicine, Bronx, NYMD, PhD05/2012Biomedical Sciences
    Memorial Sloan Kettering Cancer Center, New York, NY06/2013Transitional Year Internship
    University of Chicago, Chicago, IL06/2017Radiation Oncology Residency

    Collapse Overview 
    Collapse Overview
    I am a board-certified radiation oncologist specializing in management of genitourinary malignancies, including prostate, bladder, renal, and testicular malignancies. My clinical areas of expertise include high dose rate (HDR) prostate brachytherapy, stereotactic body radiation therapy (SBRT), and bladder-preserving trimodality therapy.

    My research interests involve using new technologies, such as advanced imaging and genomic analysis, to improve radiation therapy for genitourinary malignancies. For example, in collaboration with the department of radiology, I am utilizing PSMA PET to map patterns of prostate cancer progression and relapse in the newly diagnosed and post-treatment settings. I am also investigating the use of HDR prostate brachytherapy in technically challenging scenarios, including patients with a prior history of transurethral resection of the prostate and patients who previously received pelvic radiation.

    With regards to ongoing clinical trials, I am the radiation oncology site primary investigator for the UCSF institutional clinical trial investigating prostate SBRT and immunotherapy for newly diagnosed oligometastatic prostate cancer (CC#16703). I am the site PI for the FORMULA-509 trial (CC#18551), a multicenter randomized trial evaluating the use of apalutamide and abiraterone during post-prostatectomy salvage radiation therapy for prostate cancer patients with high-risk features. I am the site PI for NRG Oncology RTOG 3506 clinical trial evaluating the use of enzalutamide in patients during post-prostatectomy salvage radiation therapy for prostate cancer patients with high-risk features. In collaboration with UCSF and SFVA pathology departments, I am investigating the genomic landscape of variant histology prostate cancers in the interest of developing novel therapeutics.

    I am interested in expanding the use of ablative radiation techniques. In collaboration with colleagues in the department of cardiology, I am working to bring a stereotactic body radiation therapy program for refractory ventricular arrhythmias to UCSF.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Salvage high dose rate brachytherapy for recurrent prostate cancer after definitive radiation. Pract Radiat Oncol. 2021 May 30. Wu SY, Wong AC, Shinohara K, Roach M, Cunha JAM, Valdes G, Hsu IC. PMID: 34077809.
      View in: PubMed   Mentions:
    2. TERT promoter mutations and other prognostic factors in patients with advanced urothelial carcinoma treated with an immune checkpoint inhibitor. J Immunother Cancer. 2021 May; 9(5). de Kouchkovsky I, Zhang L, Philip EJ, Wright F, Kim DM, Natesan D, Kwon D, Ho H, Ho S, Chan E, Porten SP, Wong AC, Desai A, Huang FW, Chou J, Oh DY, Pruthi RS, Fong L, Small EJ, Friedlander TW, Koshkin V. PMID: 33980590.
      View in: PubMed   Mentions:    Fields:    
    3. Prostate-specific Membrane Antigen and Fluciclovine Transporter Genes are Associated with Variable Clinical Features and Molecular Subtypes of Primary Prostate Cancer. Eur Urol. 2021 Apr 08. Chu CE, Alshalalfa M, Sjöström M, Zhao SG, Liu Y, Chou J, Herlemann A, Mahal B, Kishan A, Spratt DE, Cooperberg M, Small E, Wong A, Porten S, Hope TA, Ross AE, Davicioni E, Nguyen P, Karnes RJ, Carroll PR, Schaeffer E, Feng FY. PMID: 33840559.
      View in: PubMed   Mentions:    Fields:    
    4. A Virion-Based Assay for Glycoprotein Thermostability Reveals Key Determinants of Filovirus Entry and Its Inhibition. J Virol. 2020 08 31; 94(18). Bortz RH, Wong AC, Grodus MG, Recht HS, Pulanco MC, Lasso G, Anthony SJ, Mittler E, Jangra RK, Chandran K. PMID: 32611759.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. NRG Oncology Updated International Consensus Atlas on Pelvic Lymph Node Volumes for Intact and Postoperative Prostate Cancer. Int J Radiat Oncol Biol Phys. 2021 Jan 01; 109(1):174-185. Hall WA, Paulson E, Davis BJ, Spratt DE, Morgan TM, Dearnaley D, Tree AC, Efstathiou JA, Harisinghani M, Jani AB, Buyyounouski MK, Pisansky TM, Tran PT, Karnes RJ, Chen RC, Cury FL, Michalski JM, Rosenthal SA, Koontz BF, Wong AC, Nguyen PL, Hope TA, Feng F, Sandler HM, Lawton CAF. PMID: 32861817.
      View in: PubMed   Mentions:    Fields:    
    6. Noninvasive ventricular tachycardia ablation: Should we apply the accelerator or the brake? Heart Rhythm. 2020 Aug; 17(8):1249-1250. Dewland TA, Wong AC, Gerstenfeld EP. PMID: 32289468.
      View in: PubMed   Mentions:    Fields:    
    7. Mouse- and patient-derived CAM xenografts for studying metastatic renal cell carcinoma. Enzymes. 2019; 46:59-80. Ishihara M, Hu J, Wong A, Cano-Ruiz C, Wu L. PMID: 31727277.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    8. Histological features and prognostic significance of treatment effect in lymph node metastasis in head and neck squamous cell carcinoma. Histopathology. 2019 Jan; 74(2):321-331. Scherpelz KP, Wong AC, Lingen MW, Taxy JB, Cipriani NA. PMID: 30144145.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Late toxicity after post-prostatectomy intensity modulated radiation therapy: Evaluating normal-tissue sparing guidelines. Adv Radiat Oncol. 2018 Jul-Sep; 3(3):339-345. Akthar AS, Wong AC, Parekh AD, Hubert G, Son CH, Pelizzari CA, Liauw SL. PMID: 30202803.
      View in: PubMed   Mentions:
    10. PMRT: Please Mind Randomized Trials. Int J Radiat Oncol Biol Phys. 2017 08 01; 98(5):976-977. Wong AC, Chmura SJ. PMID: 28721908.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. A feasibility study of 2-mm bolus for postmastectomy radiation therapy. Pract Radiat Oncol. 2017 May - Jun; 7(3):161-166. Das LC, Golden DW, Perevalova E, Wong AC, De Nardo K, Stepaniak C, Joyce DS, McCabe BP, Hasan Y, Chmura SJ, McCall A. PMID: 28089526.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    12. Clinical and molecular markers of long-term survival after oligometastasis-directed stereotactic body radiotherapy (SBRT). Cancer. 2016 07 15; 122(14):2242-50. Wong AC, Watson SP, Pitroda SP, Son CH, Das LC, Stack ME, Uppal A, Oshima G, Khodarev NN, Salama JK, Weichselbaum RR, Chmura SJ. PMID: 27206146.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    13. Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs. Oncotarget. 2016 May 03; 7(18):26496-515. Ranoa DR, Parekh AD, Pitroda SP, Huang X, Darga T, Wong AC, Huang L, Andrade J, Staley JP, Satoh T, Akira S, Weichselbaum RR, Khodarev NN. PMID: 27034163.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    14. Physicians' beliefs about the benefits and risks of adjuvant therapies for stage II and stage III colorectal cancer. J Oncol Pract. 2014 Sep; 10(5):e360-7. Wong AC, Stock S, Schrag D, Kahn KL, Salz T, Charlton ME, Rogers SO, Goodman KA, Keating NL. PMID: 24986112.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. A novel method for accurate and reproducible functional cup positioning in total hip arthroplasty. J Arthroplasty. 2013 Aug; 28(7):1200-5. Meftah M, Yadav A, Wong AC, Ranawat AS, Ranawat CS. PMID: 23462497.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    16. Biomarker and pharmacologic evaluation of the ?-secretase inhibitor PF-03084014 in breast cancer models. Clin Cancer Res. 2012 Sep 15; 18(18):5008-19. Zhang CC, Pavlicek A, Zhang Q, Lira ME, Painter CL, Yan Z, Zheng X, Lee NV, Ozeck M, Qiu M, Zong Q, Lappin PB, Wong A, Rejto PA, Smeal T, Christensen JG. PMID: 22806875.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    17. Pain management after total knee arthroplasty using a multimodal approach. Orthopedics. 2012 May; 35(5):e660-4. Meftah M, Wong AC, Nawabi DH, Yun RJ, Ranawat AS, Ranawat CS. PMID: 22588407.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    18. Structural basis for differential neutralization of ebolaviruses. Viruses. 2012 04; 4(4):447-70. Bale S, Dias JM, Fusco ML, Hashiguchi T, Wong AC, Liu T, Keuhne AI, Li S, Woods VL, Chandran K, Dye JM, Saphire EO. PMID: 22590681.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    19. A shared structural solution for neutralizing ebolaviruses. Nat Struct Mol Biol. 2011 Nov 20; 18(12):1424-7. Dias JM, Kuehne AI, Abelson DM, Bale S, Wong AC, Halfmann P, Muhammad MA, Fusco ML, Zak SE, Kang E, Kawaoka Y, Chandran K, Dye JM, Saphire EO. PMID: 22101933.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    20. Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature. 2011 Aug 24; 477(7364):340-3. Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. PMID: 21866103.
      View in: PubMed   Mentions: 439     Fields:    Translation:HumansAnimalsCells
    21. PF-03732010: a fully human monoclonal antibody against P-cadherin with antitumor and antimetastatic activity. Clin Cancer Res. 2010 Nov 01; 16(21):5177-88. Zhang CC, Yan Z, Zhang Q, Kuszpit K, Zasadny K, Qiu M, Painter CL, Wong A, Kraynov E, Arango ME, Mehta PP, Popoff I, Casperson GF, Los G, Bender S, Anderes K, Christensen JG, VanArsdale T. PMID: 20829331.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    22. A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry. J Virol. 2010 Jan; 84(1):163-75. Wong AC, Sandesara RG, Mulherkar N, Whelan SP, Chandran K. PMID: 19846533.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    23. PF-00477736 mediates checkpoint kinase 1 signaling pathway and potentiates docetaxel-induced efficacy in xenografts. Clin Cancer Res. 2009 Jul 15; 15(14):4630-40. Zhang C, Yan Z, Painter CL, Zhang Q, Chen E, Arango ME, Kuszpit K, Zasadny K, Hallin M, Hallin J, Wong A, Buckman D, Sun G, Qiu M, Anderes K, Christensen JG. PMID: 19584159.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    24. Drosophila hnRNP A1 homologs Hrp36/Hrp38 enhance U2-type versus U12-type splicing to regulate alternative splicing of the prospero twintron. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2577-82. Borah S, Wong AC, Steitz JA. PMID: 19196985.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    25. An intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomes. Mol Cell Biol. 2004 Mar; 24(5):1855-69. Scamborova P, Wong A, Steitz JA. PMID: 14966268.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    26. JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. Genes Dev. 2003 May 15; 17(10):1271-80. Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ. PMID: 12756228.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
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