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James Grenert, MD, PhD

Title(s)Professor, Pathology
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone628-206-6576
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    MayoM.D.2000School of Medicine

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. APOBEC signatures and high tumour mutational burden as predictors of clinical outcomes and response to therapy in patients with urothelial carcinoma. Annals of Oncology. 2020 Sep 1; 31:s593. D. Natesan, L. Zhang, H. Martell, P. Devine, B. Stohr, J. Grenert, J. Van Ziffle, N. Joseph, B.C. Bastian, S. Umetsu, C. Onodera, E. Chan, A. Desai, S. Porten, J. Chou, T. Friedlander, L. Fong, E.J. Small, A. Sweet-Cordero, V.S. Koshkin. .
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    2. Prevalence of Partial Hydatidiform Mole in Products of Conception From Gestations With Fetal Triploidy Merits Reflex Genotype Testing Independent of the Morphologic Appearance of the Chorionic Villi. Am J Surg Pathol. 2020 06; 44(6):849-858. Han LM, Grenert JP, Wiita AP, Quinn M, Fujimoto VY, Rabban JT. PMID: 32205485.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Correlation of tumor mutational burden (TMB) with molecular profiling and clinical characteristics in patients with bladder cancer. Journal of Clinical Oncology. 2020 May 20; 38(15_suppl):e17025-e17025. Divya Natesan, Henry Martell, Patrick Devine, Bradley A. Stohr, James P. Grenert, Jessica Van Ziffle, Nancy M. Joseph, Boris C. Bastian, Sarah E Umetsu, Courtney Onodera, Emily Chan, Arpita Desai, Anthony C. Wong, Sima P. Porten, Jonathan Chou, Terence W. Friedlander, Eric Jay Small, Lawrence Fong, Eric Alejandro Sweet-Cordero, Vadim S Koshkin. .
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    4. Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Acta Neuropathol. 2020 06; 139(6):1071-1088. Mondal G, Lee JC, Ravindranathan A, Villanueva-Meyer JE, Tran QT, Allen SJ, Barreto J, Gupta R, Doo P, Van Ziffle J, Onodera C, Devine P, Grenert JP, Samuel D, Li R, Metrock LK, Jin LW, Antony R, Alashari M, Cheshier S, Whipple NS, Bruggers C, Raffel C, Gupta N, Kline CN, Reddy A, Banerjee A, Hall MD, Mehta MP, Khatib Z, Maher OM, Brathwaite C, Pekmezci M, Phillips JJ, Bollen AW, Tihan T, Lucas JT, Broniscer A, Berger MS, Perry A, Orr BA, Solomon DA. PMID: 32303840.
      View in: PubMed   Mentions: 1     Fields:    
    5. Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features. Acta Neuropathol. 2020 05; 139(5):953-957. Sloan EA, Hilz S, Gupta R, Cadwell C, Ramani B, Hofmann J, Kline CN, Banerjee A, Reddy A, Oberheim Bush NA, Chang S, Braunstein S, Chang EF, Raffel C, Gupta N, Sun PP, Kim JYH, Moes G, Alva E, Li R, Bruggers CS, Alashari M, Wetmore C, Garg S, Dishop M, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Berger MS, Costello JF, Perry A, Solomon DA. PMID: 32157385.
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    6. Molecular characterization of a gastric cancer transmitted from an organ donor to four transplant recipients. Journal of Clinical Oncology. 2020 Feb 1; 38(4_suppl):414-414. Chloe Evelyn Atreya, Meyeon Park, James P. Grenert, Spencer Behr, Amalia Gonzalez, Jonathan Chou, Samantha Maisel, Terence W. Friedlander, Chris E. Freise, Jun Shoji, Thomas John Semrad, Peter Chin-Hong, Eric A. Collisson, Jessica Van Ziffle. .
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    7. Clinicopathologic and molecular features of intracranial desmoplastic small round cell tumors. Brain Pathol. 2020 03; 30(2):213-225. Lee JC, Villanueva-Meyer JE, Ferris SP, Cham EM, Zucker J, Cooney T, Gilani A, Kleinschmidt-DeMasters BK, Trembath D, Mafra M, Chiang J, Ellison DW, Cho SJ, Horvai AE, Van Ziffle J, Onodera C, Devine P, Grenert JP, de Voijs CMA, van Blokland WTM, de Leng WWJ, Ploegmakers MJ, Flucke U, Pekmezci M, Bollen AW, Tihan T, Koelsche C, von Deimling A, Wesseling P, Solomon DA, Perry A. PMID: 31837177.
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    8. Next-Generation Sequencing of Retinoblastoma Identifies Pathogenic Alterations beyond RB1 Inactivation That Correlate with Aggressive Histopathologic Features. Ophthalmology. 2020 Jun; 127(6):804-813. Afshar AR, Pekmezci M, Bloomer MM, Cadenas NJ, Stevers M, Banerjee A, Roy R, Olshen AB, Van Ziffle J, Onodera C, Devine WP, Grenert JP, Bastian BC, Solomon DA, Damato BE. PMID: 32139107.
      View in: PubMed   Mentions: 1     Fields:    
    9. PATH-38. ROSETTE-FORMING GLIONEURONAL TUMOR IS DEFINED BY FGFR1 ACTIVATING ALTERATIONS WITH FREQUENT ACCOMPANYING PI3K AND MAPK PATHWAY MUTATIONS. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi151-vi152. Lucas Calixto-Hope, Julieann Lee, Emily Sloan, Jeffrey Hofmann, Jessica Van Ziffle, Courtney Onodera, James Grenert, Patrick Devine, Cassie Kline, Anu Banerjee, Jennifer Clarke, Jennie Taylor, Nancy Ann Oberheim-Bush, Robin Buerki, Nicholas Butowski, Susan Chang, Mike McDermott, Manish Aghi, Philip Theodosopoulos, Shawn Hervey-Jumper, Mitchel Berger, Corey Raffel, Nalin Gupta, Bette Kleinschmidt-DeMasters, Matthew Wood, Marjorie Grafe, Hua Guo, Peter Sun, Joseph Torkildson, Tabitha Cooney, Cynthia Fata, David Scharnhorst, David Samuel, Serguei Bannykh, Ziad Khatib, Ossama Maher, Gabriel Chamyan, Liset Pelaez, Carole Brathwaite, Lee-way Jin, Mirna Lechpammer, Donald Born, Hannes Vogel, Han Lee, Joanna Phillips, Melike Pekmezci, Andrew Bollen, Tarik Tihan, Arie Perry, David Solomon. .
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    10. PATH-66. THE GENOMIC LANDSCAPE OF SPINAL CORD EPENDYMOMA. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi158-vi158. Biswarathan Ramani, Javier Villanueva-Meyer, Christine Glastonbury, Ece Meram, Kyle Walsh, Jennie Taylor, Jessica van Ziffle, Courtney Onodera, James Grenert, Andrew Bollen, Arie Perry, Tarik Tihan, David Solomon, Melike Pekmezci. .
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    11. Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features. Brain Pathol. 2020 05; 30(3):479-494. Lucas CG, Villanueva-Meyer JE, Whipple N, Oberheim Bush NA, Cooney T, Chang S, McDermott M, Berger M, Cham E, Sun PP, Putnam A, Zhou H, Bollo R, Cheshier S, Poppe MM, Fung KM, Sung S, Glenn C, Fan X, Bannykh S, Hu J, Danielpour M, Li R, Alva E, Johnston J, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. PMID: 31609499.
      View in: PubMed   Mentions: 1     Fields:    
    12. Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas. Acta Neuropathol. 2019 11; 138(5):877-881. Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, McDermott M, Berger M, Raffel C, Gupta N, Sun PP, Li Y, Shah V, Cha S, Braunstein S, Raleigh DR, Samuel D, Scharnhorst D, Fata C, Guo H, Moes G, Kim JYH, Koschmann C, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Phillips JJ, Tihan T, Bollen AW, Perry A, Solomon DA. PMID: 31515627.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. TP53 structural variants in metastatic prostatic carcinoma. PLoS One. 2019; 14(6):e0218618. Sirohi D, Devine P, Grenert JP, van Ziffle J, Simko JP, Stohr BA. PMID: 31216325.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis. Brain Pathol. 2020 01; 30(1):46-62. Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, Kline CN, Gupta N, Raffel C, Samuel D, Ruiz-Diaz I, Magaki S, Wilson D, Neltner J, Al-Hajri Z, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Schniederjan M, Cha S, Perry A, Solomon DA. PMID: 31104347.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1. Acta Neuropathol. 2019 03; 137(3):521-525. Lee JC, Villanueva-Meyer JE, Ferris SP, Sloan EA, Hofmann JW, Hattab EM, Williams BJ, Guo H, Torkildson J, Florez A, Van Ziffle J, Onodera C, Grenert JP, Cho SJ, Horvai AE, Jones DTW, Pfister SM, Koelsche C, von Deimling A, Korshunov A, Perry A, Solomon DA. PMID: 30649606.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    16. The genetic landscape of anaplastic pleomorphic xanthoastrocytoma. Brain Pathol. 2019 01; 29(1):85-96. Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Bastian BC, Grenert JP, Kline CN, Mueller S, Banerjee A, Nicolaides T, Gupta N, Berger MS, Lee HS, Pekmezci M, Tihan T, Bollen AW, Perry A, Shieh JTC, Solomon DA. PMID: 30051528.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    17. Oligodendrogliomas, IDH-mutant and 1p/19q-codeleted, arising during teenage years often lack TERT promoter mutation that is typical of their adult counterparts. Acta Neuropathol Commun. 2018 09 19; 6(1):95. Lee J, Putnam AR, Chesier SH, Banerjee A, Raffel C, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Perry A, Solomon DA. PMID: 30231927.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. The genetic landscape of gliomas arising after therapeutic radiation. Acta Neuropathol. 2019 01; 137(1):139-150. López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C, Gupta N, Kunwar S, Mummaneni P, Aghi M, Theodosopoulos P, Berger M, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. PMID: 30196423.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    19. Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42. Mod Pathol. 2019 01; 32(1):88-99. Stevers M, Rabban JT, Garg K, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Zaloudek C, Solomon DA. PMID: 30171198.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile. Acta Neuropathol. 2018 08; 136(2):339-343. Solomon DA, Korshunov A, Sill M, Jones DTW, Kool M, Pfister SM, Fan X, Bannykh S, Hu J, Danielpour M, Li R, Johnston J, Cham E, Cooney T, Sun PP, Oberheim Bush NA, McDermott M, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Villanueva-Meyer JE, Pekmezci M, Bollen AW, Perry A. PMID: 30006677.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. The genetic landscape of ganglioglioma. Acta Neuropathol Commun. 2018 06 07; 6(1):47. Pekmezci M, Villanueva-Meyer JE, Goode B, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Chamyan G, Maher OM, Khatib Z, Kleinschmidt-DeMasters BK, Samuel D, Mueller S, Banerjee A, Clarke JL, Cooney T, Torkildson J, Gupta N, Theodosopoulos P, Chang EF, Berger M, Bollen AW, Perry A, Tihan T, Solomon DA. PMID: 29880043.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    22. Polyoma virus-associated carcinomas of the urologic tract: a clinicopathologic and molecular study. Mod Pathol. 2018 09; 31(9):1429-1441. Sirohi D, Vaske C, Sanborn Z, Smith SC, Don MD, Lindsey KG, Federman S, Vankalakunti M, Koo J, Bose S, Peralta-Venturina M, Ziffle JV, Grenert JP, Miller S, Chiu C, Amin MB, Simko JP, Stohr BA, Luthringer DJ. PMID: 29765141.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Hepatic angiomyolipoma: mutation analysis and immunohistochemical pitfalls in diagnosis. Histopathology. 2018 Jul; 73(1):101-108. Yan Z, Grenert JP, Joseph NM, Ren C, Chen X, Shafizadeh N, Kakar S. PMID: 29512829.
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    24. Genomic profile of appendiceal goblet cell carcinoid is distinct compared to appendiceal neuroendocrine tumor and conventional adenocarcinoma. Hum Pathol. 2018 07; 77:166-174. Wen KW, Grenert JP, Joseph NM, Shafizadeh N, Huang A, Hosseini M, Kakar S. PMID: 29634977.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. Silver microparticles plus fibrin tissue sealant prevents incisional hernias in rats. J Surg Res. 2018 07; 227:130-136. Primus FE, Young DM, Grenert JP, Harris HW. PMID: 29804844.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    26. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nat Commun. 2018 02 23; 9(1):810. Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, Louis DN, Yong WH, Lopes MB, Rosenblum MK, Butowski N, Tihan T, Bollen AW, Phillips JJ, Wiita AP, Yeh I, Jacobson MP, Bastian BC, Perry A, Solomon DA. PMID: 29476136.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    27. Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation. Acta Neuropathol. 2018 04; 135(4):635-638. Iorgulescu JB, Van Ziffle J, Stevers M, Grenert JP, Bastian BC, Chavez L, Stichel D, Buchhalter I, Samuel D, Nicolaides T, Banerjee A, Mueller S, Gupta N, Tihan T, Bollen AW, Northcott PA, Kool M, Pfister S, Korshunov A, Perry A, Solomon DA. PMID: 29435664.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    28. Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. Mod Pathol. 2018 04; 31(4):660-673. Goode B, Joseph NM, Stevers M, Van Ziffle J, Onodera C, Talevich E, Grenert JP, Yeh I, Bastian BC, Phillips JJ, Garg K, Rabban JT, Zaloudek C, Solomon DA. PMID: 29148537.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    29. Renal NUT carcinoma: a case report. Histopathology. 2018 02; 72(3):528-530. Sirohi D, Garg K, Simko JP, Grenert JP. PMID: 28837236.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Angiocentric glioma with MYB-QKI fusion located in the brainstem, rather than cerebral cortex. Acta Neuropathol. 2017 Oct; 134(4):671-673. Chan E, Bollen AW, Sirohi D, Van Ziffle J, Grenert JP, Kline CN, Tihan T, Perry A, Gupta N, Solomon DA. PMID: 28776091.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation? Cancer Genet. 2017 Oct; 216-217:74-78. Foley N, Van Ziffle J, Yu J, Qi Z, Grenert JP, Yeh I, Bastian B, Kogan S, Mannis GN. PMID: 29025598.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    32. Concomitant Epstein-Barr Virus-associated smooth muscle tumor and granulomatous inflammation of the liver. Pathol Res Pract. 2017 Oct; 213(10):1306-1309. Can NT, Grenert JP, Vohra P. PMID: 28756985.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Genomic profiling of breast secretory carcinomas reveals distinct genetics from other breast cancers and similarity to mammary analog secretory carcinomas. Mod Pathol. 2017 08; 30(8):1086-1099. Krings G, Joseph NM, Bean GR, Solomon D, Onodera C, Talevich E, Yeh I, Grenert JP, Hosfield E, Crawford ED, Jordan RC, van Zante A, Zaloudek C, Shin SJ, Chen YY. PMID: 28548128.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    34. Targeted next-generation DNA sequencing of paired tumor and normal DNA to reveal frequent actionable germline alterations. Journal of Clinical Oncology. 2017 May 20; 35(15_suppl):11575-11575. Wolfgang Michael Korn, Iwei Yey, Jessica Van Ziffle, James P Grenert, Nancy Joseph, David A. Solomon, Megan Laurance, Eric Talevich, Courtney Onodera, Gregor Krings, Bradley A. Stohr, Amie Blanco, Boris C. Bastian. .
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    35. Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro Oncol. 2017 05 01; 19(5):699-709. Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, Tihan T, Bollen AW, Phillips JJ, Korn WM, Yeh I, Bastian BC, Gupta N, Mueller S, Perry A, Nicolaides T, Solomon DA. PMID: 28453743.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    36. Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice. Cell Mol Gastroenterol Hepatol. 2017 Sep; 4(2):223-236. Duwaerts CC, Amin AM, Siao K, Her C, Fitch M, Beysen C, Turner SM, Goodsell A, Baron JL, Grenert JP, Cho SJ, Maher JJ. PMID: 28649594.
      View in: PubMed   Mentions: 1     Fields:    
    37. Uveal Ganglioneuroma due to Germline PTEN Mutation (Cowden Syndrome) Presenting as Unilateral Infantile Glaucoma. Ocul Oncol Pathol. 2017 Jul; 3(2):122-128. DeParis SW, Bloomer M, Han Y, Vagefi MR, Shieh JTC, Solomon DA, Grenert J, de Alba Campomanes AG. PMID: 28868283.
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    38. Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro-Oncology. 2016 Nov 14; now254. Cassie N. Kline, Nancy M. Joseph, James P. Grenert, Jessica van Ziffle, Eric Talevich, Courtney Onodera, Mariam Aboian, Soonmee Cha, David R. Raleigh, Steve Braunstein, Joseph Torkildson, David Samuel, Michelle Bloomer, Alejandra G. de Alba Campomanes, Anuradha Banerjee, Nicholas Butowski, Corey Raffel, Tarik Tihan, Andrew W. Bollen, Joanna J. Phillips, W. Michael Korn, Iwei Yeh, Boris C. Bastian, Nalin Gupta, Sabine Mueller, Arie Perry, Theodore Nicolaides, David A. Solomon. .
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    39. CHIP(-/-)-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: Therapeutic Implications. Sci Rep. 2016 07 12; 6:29423. Kim SM, Grenert JP, Patterson C, Correia MA. PMID: 27406999.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    40. Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity. Mod Pathol. 2016 09; 29(9):1012-27. Liu SY, Joseph NM, Ravindranathan A, Stohr BA, Greenland NY, Vohra P, Hosfield E, Yeh I, Talevich E, Onodera C, Van Ziffle JA, Grenert JP, Bastian BC, Chen YY, Krings G. PMID: 27255162.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    41. TB-02UPFRONT, REAL-TIME TUMOR AND GERMLINE SEQUENCING OF PEDIATRIC BRAIN TUMOR PATIENTS: THE UCSF EXPERIENCE. Neuro-Oncology. 2016 Jun 1; 18(suppl 3):iii169.2-iii169. Cassie Kline, David Solomon, Arie Perry, Boris Bastian, Nancy Joseph, Joanna Phillips, Tarik Tihan, Iwei Yeh, Jessica Van Ziffle, James Grenert, Andrew Bollen, Sabine Mueller, Anuradha Banerjee, Nalin Gupta, Corey Raffel, Steve Braunstein, Soonmee Cha, Mariam Aboian, David Samuel, Joseph Torkildson, Alejandra de Alba Campomanes, Theodore Nicolaides. .
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    42. Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha. Hepatology. 2016 07; 64(1):261-75. Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT. PMID: 26755329.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    43. Inactivating MUTYH germline mutations in pediatric patients with high-grade midline gliomas. Neuro Oncol. 2016 05; 18(5):752-3. Kline CN, Joseph NM, Grenert JP, van Ziffle J, Yeh I, Bastian BC, Mueller S, Solomon DA. PMID: 26902849.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    44. Hereditary Nonpolyposis Colorectal Cancer and Lynch Syndrome. Molecular Pathology in Clinical Practice. 2016 Jan 1; 339-350. James P. Grenert. .
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    45. Applications of STR Genotyping in Surgical Pathology. AJSP Review and Reports. 2016 Jan 1; 21(2):103-106. Anthony Halfacre, Jessica Van Ziffle, James P. Grenert, Nancy M. Joseph. .
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    46. Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury. J Nutr Biochem. 2016 Mar; 29:12-20. Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ. PMID: 26895660.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    47. Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis. BMC Gastroenterol. 2015 Jun 24; 15:72. Pierce AA, Pickens MK, Siao K, Grenert JP, Maher JJ. PMID: 26103964.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    48. Association of tumor morphology with mismatch-repair protein status in older endometrial cancer patients: implications for universal versus selective screening strategies for Lynch syndrome. Am J Surg Pathol. 2014 Jun; 38(6):793-800. Rabban JT, Calkins SM, Karnezis AN, Grenert JP, Blanco A, Crawford B, Chen LM. PMID: 24503759.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    49. Loss of heterozygosity and microsatellite instability are rare in sporadic dedifferentiated liposarcoma: a study of 43 well-characterized cases. Arch Pathol Lab Med. 2014 Jun; 138(6):823-7. Davis JL, Grenert JP, Horvai AE. PMID: 24878023.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    50. Hepatocellular carcinoma arising in adenoma: similar immunohistochemical and cytogenetic features in adenoma and hepatocellular carcinoma portions of the tumor. Mod Pathol. 2014 Nov; 27(11):1499-1509. Kakar S, Grenert JP, Paradis V, Pote N, Jakate S, Ferrell LD. PMID: 24743216.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    51. Lack of association of BRAF mutation with negative prognostic indicators in papillary thyroid carcinoma: the University of California, San Francisco, experience. JAMA Otolaryngol Head Neck Surg. 2013 Nov; 139(11):1164-70. Gouveia C, Can NT, Bostrom A, Grenert JP, van Zante A, Orloff LA. PMID: 24030686.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    52. A multicenter study directly comparing the diagnostic accuracy of gene expression profiling and immunohistochemistry for primary site identification in metastatic tumors. Am J Surg Pathol. 2013 Jul; 37(7):1067-75. Handorf CR, Kulkarni A, Grenert JP, Weiss LM, Rogers WM, Kim OS, Monzon FA, Halks-Miller M, Anderson GG, Walker MG, Pillai R, Henner WD. PMID: 23648464.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    53. Pilocytic astrocytomas of the optic nerve and their relation to pilocytic astrocytomas elsewhere in the central nervous system. Mod Pathol. 2013 Oct; 26(10):1279-87. Reis GF, Bloomer MM, Perry A, Phillips JJ, Grenert JP, Karnezis AN, Tihan T. PMID: 23702730.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    54. A rare presentation of abdominal pain: idiopathic mesenteric phlebosclerosis. Am J Gastroenterol. 2012 Nov; 107(11):1759-60. Siao D, Thoeni R, Grenert JP, Day LW. PMID: 23160302.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    55. Atypical hepatocellular adenoma-like neoplasms with ß-catenin activation show cytogenetic alterations similar to well-differentiated hepatocellular carcinomas. Hum Pathol. 2013 May; 44(5):750-8. Evason KJ, Grenert JP, Ferrell LD, Kakar S. PMID: 23084586.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    56. A Rare Presentation of Abdominal Pain: Idiopathic Mesenteric Phlebosclerosis. The American Journal of Gastroenterology. 2012 Oct 1; 107:s457-s458. Derrick Siao, Ruedi Thoeni, James Grenert, Lukejohn Day. .
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    57. Ovarian endometrioid adenocarcinoma: incidence and clinical significance of the morphologic and immunohistochemical markers of mismatch repair protein defects and tumor microsatellite instability. Am J Surg Pathol. 2012 Feb; 36(2):163-72. Aysal A, Karnezis A, Medhi I, Grenert JP, Zaloudek CJ, Rabban JT. PMID: 22189970.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    58. Gene expression profiling from formalin-fixed, paraffin-embedded tissue for tumor diagnosis. Clin Chim Acta. 2011 Jul 15; 412(15-16):1462-4. Grenert JP, Smith A, Ruan W, Pillai R, Wu AH. PMID: 21497155.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    59. Identifying Lynch syndrome in women with endometrial cancer. Gynecologic Oncology. 2011 Mar 1; 120:s34. L. Chen, J. Holstein, A. Blanco, J. Chan, C. Powell, J. Rabban, J. Grenert, P. Conrad. .
      View in: Publisher Site   Mentions:
    60. Lynch Syndrome. Diagnostic Molecular Pathology in Practice. 2011 Jan 1; 217-225. Martin P. Powers, James P. Grenert. .
      View in: Publisher Site   Mentions:
    61. Heritable epigenetic mutation of MLHI in a mother and daughter with Lynch syndrome. Hereditary Cancer in Clinical Practice. 2010 Dec 1; 8(Suppl 1):p3. Amie M Blanco, Yunn-Yi Chen, James P Grenert, Stephen N Thibodeau, Jonathan P Terdiman. .
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    62. Stress signaling in the methionine-choline-deficient model of murine fatty liver disease. Gastroenterology. 2010 Nov; 139(5):1730-9, 1739.e1. Soon RK, Yan JS, Grenert JP, Maher JJ. PMID: 20682321.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    63. Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet. Liver Int. 2010 Sep; 30(8):1229-39. Pickens MK, Ogata H, Soon RK, Grenert JP, Maher JJ. PMID: 20536716.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    64. Strain background modifies phenotypes in the ATP8B1-deficient mouse. PLoS One. 2010 Feb 01; 5(2):e8984. Shah S, Sanford UR, Vargas JC, Xu H, Groen A, Paulusma CC, Grenert JP, Pawlikowska L, Sen S, Elferink RP, Bull LN. PMID: 20126555.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    65. PAX2 distinguishes benign mesonephric and mullerian glandular lesions of the cervix from endocervical adenocarcinoma, including minimal deviation adenocarcinoma. Am J Surg Pathol. 2010 Feb; 34(2):137-46. Rabban JT, McAlhany S, Lerwill MF, Grenert JP, Zaloudek CJ. PMID: 20061933.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    66. Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder. Hum Pathol. 2010 Apr; 41(4):485-92. Shafizadeh N, Grenert JP, Sahai V, Kakar S. PMID: 20040392.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    67. Crystal-storing histiocytosis and crystalline keratopathy caused by monoclonal gammopathy of undetermined significance. Cornea. 2009 Oct; 28(9):1081-4. de Alba Campomanes AG, Rutar T, Crawford JB, Seiff S, Goodman D, Grenert J. PMID: 19724196.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    68. Neuroendocrine tumors of the ampulla of Vater: biological behavior and surgical management. Arch Surg. 2009 Jun; 144(6):527-31. Carter JT, Grenert JP, Rubenstein L, Stewart L, Way LW. PMID: 19528385.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    69. Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome. Clin Immunol. 2009 Jul; 132(1):124-31. Cheng LE, Kanwar B, Tcheurekdjian H, Grenert JP, Muskat M, Heyman MB, McCune JM, Wara DW. PMID: 19375390.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    70. Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis. J Lipid Res. 2009 Oct; 50(10):2072-82. Pickens MK, Yan JS, Ng RK, Ogata H, Grenert JP, Beysen C, Turner SM, Maher JJ. PMID: 19295183.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    71. Expansile bone cyst and cholesteatoma of the temporal bone. Otol Neurotol. 2009 Feb; 30(2):170-3. Hwang HS, Glastonbury CM, Grenert JP, Lustig LR. PMID: 19092715.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    72. Primary ovarian carcinoid tumors may express CDX-2: a potential pitfall in distinction from metastatic intestinal carcinoid tumors involving the ovary. Int J Gynecol Pathol. 2009 Jan; 28(1):41-8. Rabban JT, Lerwill MF, McCluggage WG, Grenert JP, Zaloudek CJ. PMID: 19047909.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    73. Tumors of the ampulla of vater: histopathologic classification and predictors of survival. J Am Coll Surg. 2008 Aug; 207(2):210-8. Carter JT, Grenert JP, Rubenstein L, Stewart L, Way LW. PMID: 18656049.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    74. Actinomycosis mimicking a pancreatic head neoplasm diagnosed by EUS-guided FNA. Gastrointest Endosc. 2008 Jul; 68(1):186-7. Somsouk M, Shergill AK, Grenert JP, Harris H, Cello JP, Shah JN. PMID: 18291393.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    75. In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis. J Immunol Methods. 2008 Jan 01; 329(1-2):21-30. Kanwar B, Gao DW, Hwang AB, Grenert JP, Williams SP, Franc B, McCune JM. PMID: 17964595.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    76. Epstein-Barr virus-associated B cell lymphoproliferative disease in a child with neonatal-onset multisystem inflammatory disease. Arthritis Rheum. 2006 Oct 15; 55(5):823-5. Modica R, Emery H, Lam W, Hermiston M, Grenert J, Wirt M, von Scheven E. PMID: 17013844.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    77. Pancreatoblastoma in an adult: case report and review of the literature. J Gastrointest Surg. 2006 Jun; 10(6):829-36. Rajpal S, Warren RS, Alexander M, Yeh BM, Grenert JP, Hintzen S, Ljung BM, Bergsland EK. PMID: 16769539.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    78. Erythrophagocytosis in Gaucher cells. Arch Pathol Lab Med. 2004 Oct; 128(10):1191-2. Bitton A, Etzell J, Grenert JP, Wang E. PMID: 15387692.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    79. The importance of ATP binding and hydrolysis by hsp90 in formation and function of protein heterocomplexes. J Biol Chem. 1999 Jun 18; 274(25):17525-33. Grenert JP, Johnson BD, Toft DO. PMID: 10364185.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    80. The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation. J Biol Chem. 1997 Sep 19; 272(38):23843-50. Grenert JP, Sullivan WP, Fadden P, Haystead TA, Clark J, Mimnaugh E, Krutzsch H, Ochel HJ, Schulte TW, Sausville E, Neckers LM, Toft DO. PMID: 9295332.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansCells
    81. Differential response in cell proliferation to beta estradiol in coronary arterial vascular smooth muscle cells obtained from mature female versus male animals. Endocrinology. 1996 Nov; 137(11):5174-7. Moraghan T, Antoniucci DM, Grenert JP, Sieck GC, Johnson C, Miller VM, Fitzpatrick LA. PMID: 8895395.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    82. 901–40 Gender-related Differences in Smooth Muscle Cell Proliferation in Response to Estradiol and Dihydrotestosterone. Journal of the American College of Cardiology. 1995 Feb 1; 25(2):14a. Thomas J. Moraghan, James P. Grenert, Christopher M. Johnson, Virginia M. Miller, Lorraine A. Fitzpatrick. .
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