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Jonathan Chou, MD, PhD

TitleCLINIAL FELLOW
SchoolUCSF School of Medicine
DepartmentMedicine
Address533 Parnassus Avenue
San Francisco CA 94117
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    Collapse Biography 
    Collapse Awards and Honors
    UCSF Breast Oncology Retreat2014Poster Winner
    American Society of Cell Biology Annual Meeting - SF2013Invited Mini-Symposium Speaker - Cancer Cell Biology
    Department of Defense, Breast Cancer Research Program2010Pre-doctoral Fellowship
    California Breast Cancer Research Program2009Pre-doctoral Fellowship
    Stanford University2006Dean's Award for Academic Accomplishment
    Stanford University2006Firestone Medal for Undergraduate Thesis
    Goldwater Foundation2003Goldwater Scholar

    Collapse Overview 
    Collapse Overview
    BS in Biological Sciences, minor in Chemistry, Stanford University (2005)
    MD, PhD in Biomedical Sciences (MSTP), University of California, San Francisco. Graduate Advisor: Dr. Zena Werb (2006 - 2014)
    Intern, Department of Medicine, University of California, San Francisco (2014-2015)
    Resident, Department of Medicine, University of California, San Francisco (2015 - 2016)
    Fellow, Division of Hematology/Oncology, University of California, San Francisco (2016 - present)
    I am a physician-scientist who is broadly interested in translational oncology. My research interests include understanding cancer metastasis and the tumor microenvironment, investigating mechanisms of therapeutic resistance, and identifying novel targets to better treat metastatic disease.


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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shahi P, Wang CY, Chou J, Hagerling C, Gonzalez Veloso H, Ruderisch A, Yu Y, Lai MD, Werb Z. GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis. Oncogene. 2017 Jun 05. PMID: 28581515.
      View in: PubMed
    2. Chou J, Wallender E, Schwartz BS, et al. Respiratory Failure in a Woman 8 Months After an Allogeneic Stem Cell Transplant. JAMA Oncol. 2016 Aug 25. PMID: 27559706.
      View in: PubMed
    3. Chou J, Beutler LR, Goldschlager N. Electrocardiography Evolution in a Woman Presenting With Alcohol Withdrawal Seizures and Cocaine Use. JAMA Intern Med. 2016 May 1; 176(5):693-5. PMID: 27019877.
      View in: PubMed
    4. Chou J, Chan MF, Werb Z. Metalloproteinases: a Functional Pathway for Myeloid Cells. Microbiol Spectr. 2016 Apr; 4(2). PMID: 27227311.
      View in: PubMed
    5. Shahi P, Slorach EM, Wang CY, Chou J, Lu A, Ruderisch A, Werb Z. The Transcriptional Repressor ZNF503/Zeppo2 Promotes Mammary Epithelial Cell Proliferation and Enhances Cell Invasion. J Biol Chem. 2015 Feb 6; 290(6):3803-13. PMID: 25538248; PMCID: PMC4319044 [Available on 02/06/16].
      View in: PubMed, PubMed Central
    6. Bonnans C, Chou J, Werb Z. Remodelling the extracellular matrix in development and disease. Nat Rev Mol Cell Biol. 2014 Dec; 15(12):786-801. PMID: 25415508; PMCID: PMC4316204.
      View in: PubMed, PubMed Central
    7. Chou J, Shahi P, Werb Z. microRNA-mediated regulation of the tumor microenvironment. Cell Cycle. 2013 Oct 15; 12(20):3262-71. PMID: 24036551; PMCID: PMC3885637.
      View in: PubMed, PubMed Central
    8. Chou J, Lin JH, Brenot A, Kim JW, Provot S, Werb Z. GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat Cell Biol. 2013 Feb; 15(2):201-13. PMID: 23354167; PMCID: PMC3660859.
      View in: PubMed, PubMed Central
    9. Chou J, Werb Z. MicroRNAs play a big role in regulating ovarian cancer-associated fibroblasts and the tumor microenvironment. Cancer Discov. 2012 Dec; 2(12):1078-80. PMID: 23230184; PMCID: PMC3531831.
      View in: PubMed, PubMed Central
    10. Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, Sweeney CA, Collins CC, Gray JW, Chang HY, Werb Z. The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discov. 2012 Jul; 2(7):638-51. PMID: 22728437; PMCID: PMC3546490.
      View in: PubMed, PubMed Central
    11. Slorach EM, Chou J, Werb Z. Zeppo1 is a novel metastasis promoter that represses E-cadherin expression and regulates p120-catenin isoform expression and localization. Genes Dev. 2011 Mar 1; 25(5):471-84. PMID: 21317240; PMCID: PMC3049288.
      View in: PubMed, PubMed Central
    12. Chou J, Provot S, Werb Z. GATA3 in development and cancer differentiation: cells GATA have it! J Cell Physiol. 2010 Jan; 222(1):42-9. PMID: 19798694; PMCID: PMC2915440.
      View in: PubMed, PubMed Central
    13. Allen E, Ding J, Wang W, Pramanik S, Chou J, Yau V, Yang Y. Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival. Nature. 2005 Nov 10; 438(7065):224-8. PMID: 16227972.
      View in: PubMed
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