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Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia. Am J Hum Genet. 2021 Oct 07; 108(10):1823-1835.
Kachuri L, Jeon S, DeWan AT, Metayer C, Ma X, Witte JS, Chiang CWK, Wiemels JL, Wiemels JL, de Smith AJ. PMID: 34469753.
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Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts. Nat Commun. 2021 02 12; 12(1):970.
Graff RE, Cavazos TB, Thai KK, Kachuri L, Rashkin SR, Hoffman JD, Alexeeff SE, Blatchins M, Meyers TJ, Leong L, Tai CG, Emami NC, Corley DA, Kushi LH, Ziv E, Van Den Eeden SK, Jorgenson E, Hoffmann TJ, Habel LA, Witte JS, Sakoda LC. PMID: 33579919.
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1 Fields:
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Humans
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A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility. Cancer Res. 2021 04 01; 81(7):1695-1703.
Emami NC, Cavazos TB, Rashkin SR, Cario CL, Graff RE, Tai CG, Mefford JA, Kachuri L, Wan E, Wong S, Aaronson D, Presti J, Habel LA, Shan J, Ranatunga DK, Chao CR, Ghai NR, Jorgenson E, Sakoda LC, Kvale MN, Kwok PY, Schaefer C, Risch N, Hoffmann TJ, Van Den Eeden SK, Witte JS. PMID: 33293427.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction. Nat Commun. 2020 11 27; 11(1):6084.
Kachuri L, Graff RE, Smith-Byrne K, Meyers TJ, Rashkin SR, Ziv E, Witte JS, Johansson M. PMID: 33247094.
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6 Fields:
Translation:
Humans
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The landscape of host genetic factors involved in immune response to common viral infections. Genome Med. 2020 10 27; 12(1):93.
Kachuri L, Francis SS, Morrison ML, Wendt GA, Bossé Y, Cavazos TB, Rashkin SR, Ziv E, Witte JS. PMID: 33109261.
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11 Fields:
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Humans
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Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Nat Commun. 2020 09 04; 11(1):4423.
Rashkin SR, Graff RE, Kachuri L, Thai KK, Alexeeff SE, Blatchins MA, Cavazos TB, Corley DA, Emami NC, Hoffman JD, Jorgenson E, Kushi LH, Meyers TJ, Van Den Eeden SK, Ziv E, Habel LA, Hoffmann TJ, Sakoda LC, Witte JS. PMID: 32887889.
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17 Fields:
Translation:
Humans
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Insecticide use and risk of non-Hodgkin lymphoma subtypes: A subset meta-analysis of the North American Pooled Project. Int J Cancer. 2020 12 15; 147(12):3370-3383.
Kachuri L, Beane Freeman LE, Spinelli JJ, Blair A, Pahwa M, Koutros S, Hoar Zahm S, Cantor KP, Weisenburger DD, Pahwa P, Dosman JA, McLaughlin JR, Demers PA, Harris SA. PMID: 32574374.
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Humans
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Pesticide use and risk of Hodgkin lymphoma: results from the North American Pooled Project (NAPP). Cancer Causes Control. 2020 Jun; 31(6):583-599.
Latifovic L, Freeman LEB, Spinelli JJ, Pahwa M, Kachuri L, Blair A, Cantor KP, Zahm SH, Weisenburger DD, McLaughlin JR, Dosman JA, Pahwa P, Koutros S, Demers PA, Harris SA. PMID: 32314107.
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2 Fields:
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HumansPHPublic Health
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Silica and asbestos exposure at work and the risk of bladder cancer in Canadian men: a population-based case-control study. BMC Cancer. 2020 Mar 03; 20(1):171.
Latifovic L, Villeneuve PJ, Parent MÉ, Kachuri L, Canadian Cancer Registries Epidemiology Group , Harris SA. PMID: 32126982.
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HumansPHPublic Health
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Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility. Nat Commun. 2020 01 07; 11(1):27.
Kachuri L, Johansson M, Rashkin SR, Graff RE, Bossé Y, Manem V, Caporaso NE, Landi MT, Christiani DC, Vineis P, Liu G, Scelo G, Zaridze D, Shete SS, Albanes D, Aldrich MC, Tardón A, Rennert G, Chen C, Goodman GE, Doherty JA, Bickeböller H, Field JK, Davies MP, Dawn Teare M, Kiemeney LA, Bojesen SE, Haugen A, Zienolddiny S, Lam S, Le Marchand L, Cheng I, Schabath MB, Duell EJ, Andrew AS, Manjer J, Lazarus P, Arnold S, McKay JD, Emami NC, Warkentin MT, Brhane Y, Obeidat M, Martin RM, Relton C, Davey Smith G, Haycock PC, Amos CI, Brennan P, Witte JS, Hung RJ. PMID: 31911640.
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Humans
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Exposure to crystalline silica in Canadian workplaces and the risk of kidney cancer. Occup Environ Med. 2019 09; 76(9):668-671.
Peters CE, Bogaert L, Latifovic L, Kachuri L, Harris SA, Parent ME, Villeneuve PJ, Canadian Cancer Registries Epidemiology Group . PMID: 31413189.
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HumansPHPublic Health
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Author Correction: Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms. Nat Commun. 2019 Aug 28; 10(1):3948.
Emami NC, Kachuri L, Meyers TJ, Das R, Hoffman JD, Hoffmann TJ, Hu D, Shan J, Feng FY, Ziv E, Van Den Eeden SK, Witte JS. PMID: 31462633.
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Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms. Nat Commun. 2019 07 15; 10(1):3107.
Emami NC, Kachuri L, Meyers TJ, Das R, Hoffman JD, Hoffmann TJ, Hu D, Shan J, Feng FY, Ziv E, Van Den Eeden SK, Witte JS. PMID: 31308362.
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5 Fields:
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HumansCells
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Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer. Cancer Epidemiol Biomarkers Prev. 2019 07; 28(7):1228-1237.
Kachuri L, Helby J, Bojesen SE, Christiani DC, Su L, Wu X, Tardón A, Fernández-Tardón G, Field JK, Davies MP, Chen C, Goodman GE, Shepherd FA, Leighl NB, Tsao MS, Brhane Y, Brown MC, Boyd K, Shepshelovich D, Sun L, Amos CI, Liu G, Hung RJ. PMID: 31263055.
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3 Fields:
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HumansCells
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Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers. Int J Epidemiol. 2019 06 01; 48(3):751-766.
Kachuri L, Saarela O, Bojesen SE, Davey Smith G, Liu G, Landi MT, Caporaso NE, Christiani DC, Johansson M, Panico S, Overvad K, Trichopoulou A, Vineis P, Scelo G, Zaridze D, Wu X, Albanes D, Diergaarde B, Lagiou P, Macfarlane GJ, Aldrich MC, Tardón A, Rennert G, Olshan AF, Weissler MC, Chen C, Goodman GE, Doherty JA, Ness AR, Bickeböller H, Wichmann HE, Risch A, Field JK, Teare MD, Kiemeney LA, van der Heijden EHFM, Carroll JC, Haugen A, Zienolddiny S, Skaug V, Wünsch-Filho V, Tajara EH, Ayoub Moysés R, Daumas Nunes F, Lam S, Eluf-Neto J, Lacko M, Peters WHM, Le Marchand L, Duell EJ, Andrew AS, Franceschi S, Schabath MB, Manjer J, Arnold S, Lazarus P, Mukeriya A, Swiatkowska B, Janout V, Holcatova I, Stojsic J, Mates D, Lissowska J, Boccia S, Lesseur C, Zong X, McKay JD, Brennan P, Amos CI, Hung RJ. PMID: 30059977.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Non-Hodgkin lymphoma risk and organophosphate and carbamate insecticide use in the north American pooled project. Environ Int. 2019 06; 127:199-205.
Koutros S, Harris SA, Spinelli JJ, Blair A, McLaughlin JR, Zahm SH, Kim S, Albert PS, Kachuri L, Pahwa M, Cantor KP, Weisenburger DD, Pahwa P, Pardo LA, Dosman JA, Demers PA, Beane Freeman LE. PMID: 30928843.
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4 Fields:
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Humans
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Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis. Cancer Epidemiol Biomarkers Prev. 2019 05; 28(5):935-942.
Zhu Y, Wei Y, Zhang R, Dong X, Shen S, Zhao Y, Bai J, Albanes D, Caporaso NE, Landi MT, Zhu B, Chanock SJ, Gu F, Lam S, Tsao MS, Shepherd FA, Tardon A, Fernández-Somoano A, Fernandez-Tardon G, Chen C, Barnett MJ, Doherty J, Bojesen SE, Johansson M, Brennan P, McKay JD, Carreras-Torres R, Muley T, Risch A, Wichmann HE, Bickeboeller H, Rosenberger A, Rennert G, Saliba W, Arnold SM, Field JK, Davies MPA, Marcus MW, Wu X, Ye Y, Le Marchand L, Wilkens LR, Melander O, Manjer J, Brunnström H, Hung RJ, Liu G, Brhane Y, Kachuri L, Andrew AS, Duell EJ, Kiemeney LA, van der Heijden EH, Haugen A, Zienolddiny S, Skaug V, Grankvist K, Johansson M, Woll PJ, Cox A, Taylor F, Teare DM, Lazarus P, Schabath MB, Aldrich MC, Houlston RS, McLaughlin J, Stevens VL, Shen H, Hu Z, Dai J, Amos CI, Han Y, Zhu D, Goodman GE, Chen F, Christiani DC. PMID: 30700444.
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6 Fields:
Translation:
HumansCells
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Occupational Exposure to Diesel and Gasoline Engine Exhausts and the Risk of Kidney Cancer in Canadian Men. Ann Work Expo Health. 2018 10 15; 62(8):978-989.
Peters CE, Parent MÉ, Harris SA, Bogaert L, Latifovic L, Kachuri L, Villeneuve PJ, Canadian Cancer Registries Epidemiology Group . PMID: 30059990.
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PubMed Mentions:
1 Fields:
Translation:
HumansPHPublic Health
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Personalized Prostate Cancer Screening Based on a Single Midlife Prostate-specific Antigen Measurement. Eur Urol. 2019 03; 75(3):408-409.
Graff RE, Kachuri L, Witte JS. PMID: 30268658.
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1 Fields:
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HumansPHPublic Health
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Workplace exposure to asbestos and the risk of kidney cancer in Canadian men. Can J Public Health. 2018 08; 109(4):464-472.
Peters CE, Parent MÉ, Harris SA, Kachuri L, Latifovic L, Bogaert L, Villeneuve PJ, Canadian Cancer Registries Epidemiology Group . PMID: 30225576.
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1 Fields:
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HumansPHPublic Health
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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet. 2017 Jul; 49(7):1126-1132.
McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, Liu G, Timofeeva MN, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman CA, Wilkens LR, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden HFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty JA, Barnett MP, Chen C, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Wichmann HE, Manz J, Muley TR, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd FA, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston RS, McLaughlin J, Stevens VL, Joubert P, Lamontagne M, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Kachuri L, Artigas MS, Tobin MD, Wain LV, SpiroMeta Consortium , Rafnar T, Thorgeirsson TE, Reginsson GW, Stefansson K, Hancock DB, Bierut LJ, Spitz MR, Gaddis NC, Lutz SM, Gu F, Johnson EO, Kamal A, Pikielny C, Zhu D, Lindströem S, Jiang X, Tyndale RF, Chenevix-Trench G, Beesley J, Bossé Y, Chanock S, Brennan P, Landi MT, Amos CI. PMID: 28604730.
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114 Fields:
Translation:
Humans
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Cancer risks in a population-based study of 70,570 agricultural workers: results from the Canadian census health and Environment cohort (CanCHEC). BMC Cancer. 2017 05 19; 17(1):343.
Kachuri L, Harris MA, MacLeod JS, Tjepkema M, Peters PA, Demers PA. PMID: 28525996.
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14 Fields:
Translation:
HumansPHPublic Health
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Systematic Review of Genetic Variation in Chromosome 5p15.33 and Telomere Length as Predictive and Prognostic Biomarkers for Lung Cancer. Cancer Epidemiol Biomarkers Prev. 2016 12; 25(12):1537-1549.
Kachuri L, Latifovic L, Liu G, Hung RJ. PMID: 27566420.
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7 Fields:
Translation:
HumansCells
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Pesticide exposures and the risk of multiple myeloma in men: An analysis of the North American Pooled Project. Int J Cancer. 2016 10 15; 139(8):1703-14.
Presutti R, Harris SA, Kachuri L, Spinelli JJ, Pahwa M, Blair A, Zahm SH, Cantor KP, Weisenburger DD, Pahwa P, McLaughlin JR, Dosman JA, Freeman LB. PMID: 27261772.
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8 Fields:
Translation:
HumansPHPublic Health
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Workplace exposure to diesel and gasoline engine exhausts and the risk of colorectal cancer in Canadian men. Environ Health. 2016 Jan 14; 15:4.
Kachuri L, Villeneuve PJ, Parent MÉ, Johnson KC, Canadian Cancer Registries Epidemiology Research Group , Harris SA. PMID: 26762540.
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PubMed Mentions:
7 Fields:
Translation:
HumansPHPublic Health
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Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci. Carcinogenesis. 2016 Jan; 37(1):96-105.
Kachuri L, Amos CI, McKay JD, Johansson M, Vineis P, Bueno-de-Mesquita HB, Boutron-Ruault MC, Johansson M, Quirós JR, Sieri S, Travis RC, Weiderpass E, Le Marchand L, Henderson BE, Wilkens L, Goodman GE, Chen C, Doherty JA, Christiani DC, Wei Y, Su L, Tworoger S, Zhang X, Kraft P, Zaridze D, Field JK, Marcus MW, Davies MPA, Hyde R, Caporaso NE, Landi MT, Severi G, Giles GG, Liu G, McLaughlin JR, Li Y, Xiao X, Fehringer G, Zong X, Denroche RE, Zuzarte PC, McPherson JD, Brennan P, Hung RJ. PMID: 26590902.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Bladder cancer and occupational exposure to diesel and gasoline engine emissions among Canadian men. Cancer Med. 2015 Dec; 4(12):1948-62.
Latifovic L, Villeneuve PJ, Parent MÉ, Johnson KC, Kachuri L, Canadian Cancer Registries Epidemiology Group , Harris SA. PMID: 26511593.
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PubMed Mentions:
12 Fields:
Translation:
HumansPHPublic Health
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Authors' response. Chronic Dis Inj Can. 2014 Nov; 34(4):271.
De P, Kachuri L, Ellison LF, Semenciw R. PMID: 25408188.
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Humans
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Occupational exposure to crystalline silica and the risk of lung cancer in Canadian men. Int J Cancer. 2014 Jul 01; 135(1):138-48.
Kachuri L, Villeneuve PJ, Parent MÉ, Johnson KC, Canadian Cancer Registries Epidemiology Group , Harris SA. PMID: 24272527.
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PubMed Mentions:
18 Fields:
Translation:
HumansPHPublic Health
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Multiple pesticide exposures and the risk of multiple myeloma in Canadian men. Int J Cancer. 2013 Oct 15; 133(8):1846-58.
Kachuri L, Demers PA, Blair A, Spinelli JJ, Pahwa M, McLaughlin JR, Pahwa P, Dosman JA, Harris SA. PMID: 23564249.
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PubMed Mentions:
11 Fields:
Translation:
HumansPHPublic Health
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Cancer incidence, mortality and survival trends in Canada, 1970-2007. Chronic Dis Inj Can. 2013 Mar; 33(2):69-80.
Kachuri L, De P, Ellison LF, Semenciw R, Advisory Committee on Canadian Cancer Statistics . PMID: 23470172.
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PubMed Mentions:
25 Fields:
Translation:
Humans