Loading...

UCSF Coronavirus Response: UCSF is partnering with public agencies to address the rapidly evolving outbreak and protect our communities. The UCSF COVID-19 Resources Website provides guidance and information for our patients, faculty, staff, trainees and learners.

Qi Wen Fan, MD, PhD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
Phone415-502-1695 ext. 2
vCardDownload vCard
    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Wong RA, Luo X, Lu M, An Z, Haas-Kogan DA, Phillips JJ, Shokat KM, Weiss WA, Fan QW. Cooperative Blockade of PKCa and JAK2 Drives Apoptosis in Glioblastoma. Cancer Res. 2020 Feb 15; 80(4):709-718. PMID: 31806641.
      View in: PubMed
    2. Fan Q, An Z, Wong RA, Luo X, Lu E, Baldwin A, Mayekar MK, Haderk F, Shokat KM, Bivona TG, Weiss WA. Betacellulin drives therapy-resistance in glioblastoma. Neuro Oncol. 2019 Nov 03. PMID: 31678994.
      View in: PubMed
    3. Xujun Luo, Qi-Wen Fan, Kevan M Shokat, William A Weiss. THER-08. RAPLINK-1 COOPERATES WITH INHIBITORS OF Bcl-2/Bcl-xl TO INDUCE APOPTOSIS IN GLIOBLASTOMA. Neuro-Oncology. 2019 Apr 23; 21(Supplement_2):ii115-ii115.
      View in: Publisher Site
    4. An Z, Knobbe-Thomsen CB, Wan X, Fan QW, Reifenberger G, Weiss WA. EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma. Cancer Res. 2018 12 15; 78(24):6785-6794. PMID: 30401716.
      View in: PubMed
    5. An Z, Aksoy O, Zheng T, Fan QW, Weiss WA. Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies. Oncogene. 2018 03; 37(12):1561-1575. PMID: 29321659.
      View in: PubMed
    6. Ozlem Aksoy, Qiwen Fan, Kevan Shokat, Davide Ruggero, William Weiss. CSIG-42. UNDERSTANDING THE ROLE OF TRANSLATIONAL CONTROL IN MYCN-DRIVEN MEDULLOBLASTOMA. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi58-vi58.
      View in: Publisher Site
    7. Fan QW, Nicolaides TP, Weiss WA. Inhibiting 4EBP1 in Glioblastoma. Clin Cancer Res. 2018 01 01; 24(1):14-21. PMID: 28696243.
      View in: PubMed
    8. Fan Q, Aksoy O, Wong RA, Ilkhanizadeh S, Novotny CJ, Gustafson WC, Truong AY, Cayanan G, Simonds EF, Haas-Kogan D, Phillips JJ, Nicolaides T, Okaniwa M, Shokat KM, Weiss WA. A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma. Cancer Cell. 2017 03 13; 31(3):424-435. PMID: 28292440.
      View in: PubMed
    9. Zhang J, Yao TW, Hashizume R, Hariono S, Barkovich KJ, Fan QW, Prados M, James CD, Weiss WA, Nicolaides T. Combined BRAFV600E and MEK blockade for BRAFV600E-mutant gliomas. J Neurooncol. 2017 02; 131(3):495-505. PMID: 27848137.
      View in: PubMed
    10. QiWen Fan, Robyn Wong, Chris Novotny, Masanori Okaniwa, Theodore Nicolaides, Kevan Shokat, William Weiss. ATPS-94THIRD GENERATION mTOR INHIBITORS IN GLIOBLASTOMA. Neuro-Oncology. 2015 Nov 1; 17(suppl_5):v39-v39.
      View in: Publisher Site
    11. William Weiss, Qi-Wen Fan, Albert Baldwin, Robyn Wong, Kevan Shokat. ET-63TARGETING THE EGFR-STAT-NF-?B AXIS IN GLIOBLASTOMA. Neuro-Oncology. 2014 Nov 1; 16(suppl_5):v93-v93.
      View in: Publisher Site
    12. Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, Kozlov S, Mao JH, Van Dyke T, Kwok PY, Khan J, Balmain A, Fan Q, Weiss WA. Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. Cell Rep. 2014 Nov 06; 9(3):1034-46. PMID: 25437558.
      View in: PubMed
    13. William A. Weiss, Robyn Wong, Qi-Wen Fan, Shirin Ilkhanizadeh, Mimi Lu, Janine Beyer, Nikhil Dube, John Forsayeth, Adrian Kells, Ting Xu, Krystof Bankiewicz, Greg Ducker, Morri Feldman, Kevan Shokat. MTOR KINASE INHIBITORS AND APOPTOSIS IN GLIOBLASTOMA. Neuro-Oncology. 2014 Jul 1; 16(suppl_3):iii31-iii31.
      View in: Publisher Site
    14. Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 2013 Oct 14; 24(4):438-49. PMID: 24135280.
      View in: PubMed
    15. Fan QW, Weiss WA. Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors. Methods Mol Biol. 2012; 821:349-59. PMID: 22125077.
      View in: PubMed
    16. Fan QW, Weiss WA. Autophagy and Akt promote survival in glioma. Autophagy. 2011 May; 7(5):536-8. PMID: 21266843.
      View in: PubMed
    17. Fan QW, Cheng C, Hackett C, Feldman M, Houseman BT, Nicolaides T, Haas-Kogan D, James CD, Oakes SA, Debnath J, Shokat KM, Weiss WA. Akt and autophagy cooperate to promote survival of drug-resistant glioma. Sci Signal. 2010 Nov 09; 3(147):ra81. PMID: 21062993.
      View in: PubMed
    18. Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L. Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15; 24(10):1059-72. PMID: 20478998.
      View in: PubMed
    19. Fan QW, Weiss WA. Targeting the RTK-PI3K-mTOR axis in malignant glioma: overcoming resistance. Curr Top Microbiol Immunol. 2010; 347:279-96. PMID: 20535652.
      View in: PubMed
    20. Fan QW, Cheng C, Knight ZA, Haas-Kogan D, Stokoe D, James CD, McCormick F, Shokat KM, Weiss WA. EGFR signals to mTOR through PKC and independently of Akt in glioma. Sci Signal. 2009 Jan 27; 2(55):ra4. PMID: 19176518.
      View in: PubMed
    21. Cheng CK, Fan QW, Weiss WA. PI3K signaling in glioma--animal models and therapeutic challenges. Brain Pathol. 2009 Jan; 19(1):112-20. PMID: 19076776.
      View in: PubMed
    22. Yu W, Shewan AM, Brakeman P, Eastburn DJ, Datta A, Bryant DM, Fan QW, Weiss WA, Zegers MM, Mostov KE. Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity. EMBO Rep. 2008 Sep; 9(9):923-9. PMID: 18660750.
      View in: PubMed
    23. Fan QW, Cheng CK, Nicolaides TP, Hackett CS, Knight ZA, Shokat KM, Weiss WA. A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma. Cancer Res. 2007 Sep 01; 67(17):7960-5. PMID: 17804702.
      View in: PubMed
    24. Anders I. Persson, QiWen Fan, Joanna J. Phillips, William A. Weiss. 39 Glioma. Neurobiology of Disease. 2007 Jan 1; (Cancer1002004):433-444.
      View in: Publisher Site
    25. Fan QW, Knight ZA, Goldenberg DD, Yu W, Mostov KE, Stokoe D, Shokat KM, Weiss WA. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell. 2006 May; 9(5):341-9. PMID: 16697955.
      View in: PubMed
    26. Fan QW, Weiss WA. RNA interference against a glioma-derived allele of EGFR induces blockade at G2M. Oncogene. 2005 Jan 27; 24(5):829-37. PMID: 15580296.
      View in: PubMed
    27. Fan QW, Specht KM, Zhang C, Goldenberg DD, Shokat KM, Weiss WA. Combinatorial efficacy achieved through two-point blockade within a signaling pathway-a chemical genetic approach. Cancer Res. 2003 Dec 15; 63(24):8930-8. PMID: 14695210.
      View in: PubMed
    28. Fan QW, Zhang C, Shokat KM, Weiss WA. Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling. Curr Biol. 2002 Aug 20; 12(16):1386-94. PMID: 12194819.
      View in: PubMed