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Qi Wen Fan, MD, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentNeurology
Address1450 3rd Street
San Francisco CA 94158
Phone415-502-1695
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Fan Q, Nicolaides TP, Weiss WA. Inhibiting 4EBP1 in glioblastoma. Clin Cancer Res. 2017 Jul 10. PMID: 28696243.
      View in: PubMed
    2. Fan Q, Aksoy O, Wong RA, Ilkhanizadeh S, Novotny CJ, Gustafson WC, Truong AY, Cayanan G, Simonds EF, Haas-Kogan D, Phillips JJ, Nicolaides T, Okaniwa M, Shokat KM, Weiss WA. A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma. Cancer Cell. 2017 Mar 13; 31(3):424-435. PMID: 28292440.
      View in: PubMed
    3. Zhang J, Yao TW, Hashizume R, Hariono S, Barkovich KJ, Fan Q, Prados M, James CD, Weiss WA, Nicolaides T. Combined BRAFV600E and MEK blockade for BRAFV600E-mutant gliomas. J Neurooncol. 2017 Feb; 131(3):495-505. PMID: 27848137.
      View in: PubMed
    4. Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, Kozlov S, Mao JH, Van Dyke T, Kwok PY, Khan J, Balmain A, Fan Q, Weiss WA. Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. Cell Rep. 2014 Nov 06; 9(3):1034-46. PMID: 25437558; PMCID: PMC4251494.
    5. Fan Q, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 2013 Oct 14; 24(4):438-49. PMID: 24135280; PMCID: PMC3819146.
    6. Fan Q, Weiss WA. Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors. Methods Mol Biol. 2012; 821:349-59. PMID: 22125077; PMCID: PMC3402221.
    7. Fan Q, Weiss WA. Autophagy and Akt promote survival in glioma. Autophagy. 2011 May; 7(5):536-8. PMID: 21266843; PMCID: PMC3127214.
    8. Fan Q, Cheng C, Hackett C, Feldman M, Houseman BT, Nicolaides T, Haas-Kogan D, James CD, Oakes SA, Debnath J, Shokat KM, Weiss WA. Akt and autophagy cooperate to promote survival of drug-resistant glioma. Sci Signal. 2010 Nov 09; 3(147):ra81. PMID: 21062993; PMCID: PMC3001107.
    9. Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan Q, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L. Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15; 24(10):1059-72. PMID: 20478998; PMCID: PMC2867210.
    10. Fan Q, Weiss WA. Targeting the RTK-PI3K-mTOR axis in malignant glioma: overcoming resistance. Curr Top Microbiol Immunol. 2010; 347:279-96. PMID: 20535652; PMCID: PMC3012004.
    11. Fan Q, Cheng C, Knight ZA, Haas-Kogan D, Stokoe D, James CD, McCormick F, Shokat KM, Weiss WA. EGFR signals to mTOR through PKC and independently of Akt in glioma. Sci Signal. 2009 Jan 27; 2(55):ra4. PMID: 19176518; PMCID: PMC2793677.
    12. Cheng CK, Fan Q, Weiss WA. PI3K signaling in glioma--animal models and therapeutic challenges. Brain Pathol. 2009 Jan; 19(1):112-20. PMID: 19076776; PMCID: PMC2614703.
    13. Yu W, Shewan AM, Brakeman P, Eastburn DJ, Datta A, Bryant DM, Fan Q, Weiss WA, Zegers MM, Mostov KE. Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity. EMBO Rep. 2008 Sep; 9(9):923-9. PMID: 18660750; PMCID: PMC2529350.
    14. Fan Q, Cheng CK, Nicolaides TP, Hackett CS, Knight ZA, Shokat KM, Weiss WA. A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma. Cancer Res. 2007 Sep 01; 67(17):7960-5. PMID: 17804702; PMCID: PMC2597547.
    15. Fan Q, Knight ZA, Goldenberg DD, Yu W, Mostov KE, Stokoe D, Shokat KM, Weiss WA. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell. 2006 May; 9(5):341-9. PMID: 16697955; PMCID: PMC2925230.
    16. Fan Q, Weiss WA. RNA interference against a glioma-derived allele of EGFR induces blockade at G2M. Oncogene. 2005 Jan 27; 24(5):829-37. PMID: 15580296.
      View in: PubMed
    17. Fan Q, Specht KM, Zhang C, Goldenberg DD, Shokat KM, Weiss WA. Combinatorial efficacy achieved through two-point blockade within a signaling pathway-a chemical genetic approach. Cancer Res. 2003 Dec 15; 63(24):8930-8. PMID: 14695210.
      View in: PubMed
    18. Fan Q, Zhang C, Shokat KM, Weiss WA. Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling. Curr Biol. 2002 Aug 20; 12(16):1386-94. PMID: 12194819.
      View in: PubMed
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