Davide Ruggero, PhD

Title(s)Professor, Urology
SchoolSchool of Medicine
Address1450 3rd Street, #386
San Francisco CA 94158
ORCID ORCID Icon0000-0002-9444-5865 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Rome, La Sapienza, ItalyB.S.1994Biology
    University of Rome, La Sapienza, ItalyPh.D.1998Molecular and Cell Biology
    Collapse Awards and Honors
    1994Enichem Society Fellowship
    1998  - 2000American-Italian Cancer Foundation Fellowship
    2003Outstanding Research Fellow Award at MSKCC
    2005  - 2007V Foundation Scholar Award
    2006  - 2007Pennsylvania Department of Health Merit Award (Commonwealth Universal Research Enhancement Program)
    2008AACR Gertrude B. Elion Cancer Research Award
    2010Leukemia & Lymphoma Society Scholar Award
    2010Phi Beta Psi Sorority National Project Research Award
    2010UCSF Program for Breakthrough Biomedical Research Award
    2010Co-Chair and Organizer, 1st American Association for Cancer Research "Protein Translation and Cancer
    2011Helen Diller Family Endowed Chair of Basic Cancer Research
    2013Co-Organizer, AACR 3rd International Conference on Frontiers in Basic Cancer Research
    2013Chair, 2013 AACR Annual Meeting Major Symposium on "Stress Response Pathways in Cancer"
    2016Co-Chair and Organizer, AACR Special Conference on "Translating the cancer genome: a new frontier in
    2017Chair, Annual AACR Educational Session on "Translation Control in cancer: From Basic Science to Ther
    2017Chair, Annual AACR Educational Session on "Translation Control in cancer: From Basic Science to Ther
    2017Chair, Annual AACR Educational Session on "Translation Control in cancer: From Basic Science to Ther
    2017Chair, Annual AACR Educational Session on "Translation Control in cancer: From Basic Science to Ther
    2017Chair, Annual AACR Educational Session on "Translation Control in cancer: From Basic Science to Ther
    2018Co-Chair, 2018 Cold Spring Harbor Laboratories Meeting on Translational Control
    2019Chair, NCI Special Workshop on Dysregulation of Ribosome Biogenesis & Protein Synthesis in Cancer
    2019NCI Outstanding Investigator Award (R35)
    2019American Cancer Society (ACS) Research Professorship Award
    2020Co-Organizer, ACS “Expanding the Central Dogma to Fight Cancer” Symposium
    2020Co-Organizer, QBI Cancer Cell Symposium

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms of regulated translation control in cancer and its therapeutic implications
    NIH R35CA242986Aug 6, 2019 - Jul 31, 2026
    Role: Principal Investigator
    MYCN, mTOR and translation control in medulloblastoma
    NIH R01NS089868Sep 1, 2014 - Jun 30, 2019
    Role: Co-Principal Investigator
    X-linked Dyskeratosis Congenita and ribosomal frameshifting
    NIH R01HL119439Aug 1, 2014 - Apr 30, 2019
    Role: Co-Principal Investigator
    elF4E-Dependent Translation Control in the Oncogenic Stress Response and Cancer
    NIH R01CA184624May 1, 2014 - Apr 30, 2020
    Role: Principal Investigator
    Deciphering the role of the translational oncogenic program in Prostate Cancer
    NIH R01CA154916Sep 1, 2011 - Jun 30, 2022
    Role: Principal Investigator
    Delineating the Mechanisms Responsible for Synthetic Lethality in MYC-induced Tumorigenesis Driven by Control of Protein Synthesis
    NIH R01CA140456Jul 1, 2009 - Apr 30, 2020
    Role: Principal Investigator
    Role of ribosome impairments in X-linked Dyskeratosis Congenita pathogenesis
    NIH R01DK098057Aug 1, 2006 - Jun 30, 2017
    Role: Principal Investigator
    Role of rRNA Modifications in Dyskeratosis Congenita and Translation Control
    NIH R01HL085572Aug 1, 2006 - Jun 30, 2011
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress. Mol Cancer Res. 2024 Jan 18. Dey N, Koumenis C, Ruggero D, Fuchs SY, Diehl JA. PMID: 38236939.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages. bioRxiv. 2023 Dec 07. Susanto TT, Hung V, Levine AG, Kerr CH, Yoo Y, Chen Y, Oses-Prieto JA, Fromm L, Fujii K, Wernig M, Burlingame AL, Ruggero D, Barna M. PMID: 38106052; PMCID: PMC10723405.
      View in: PubMed   Mentions:
    3. Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer. Nat Commun. 2023 10 10; 14(1):6332. Macaya I, Roman M, Welch C, Entrialgo-Cadierno R, Salmon M, Santos A, Feliu I, Kovalski J, Lopez I, Rodriguez-Remirez M, Palomino-Echeverria S, Lonfgren SM, Ferrero M, Calabuig S, Ludwig IA, Lara-Astiaso D, Jantus-Lewintre E, Guruceaga E, Narayanan S, Ponz-Sarvise M, Pineda-Lucena A, Lecanda F, Ruggero D, Khatri P, Santamaria E, Fernandez-Irigoyen J, Ferrer I, Paz-Ares L, Drosten M, Barbacid M, Gil-Bazo I, Vicent S. PMID: 37816716; PMCID: PMC10564741.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Evolutionarily divergent mTOR remodels translatome for tissue regeneration. Nature. 2023 Aug; 620(7972):163-171. Zhulyn O, Rosenblatt HD, Shokat L, Dai S, Kuzuoglu-Öztürk D, Zhang Z, Ruggero D, Shokat KM, Barna M. PMID: 37495694.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    5. Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates. Elife. 2023 Jun 12; 12. Xu AF, Molinuevo R, Fazzari E, Tom H, Zhang Z, Menendez J, Casey KM, Ruggero D, Hinck L, Pritchard JK, Barna M. PMID: 37306301; PMCID: PMC10313321.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    6. N-myc-Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma. Cancer Res. 2023 01 04; 83(1):130-140. Kuzuoglu-Ozturk D, Aksoy O, Schmidt C, Lea R, Larson JD, Phelps RRL, Nasholm N, Holt M, Contreras A, Huang M, Wong-Michalak S, Shao H, Wechsler-Reya R, Phillips JJ, Gestwicki JE, Ruggero D, Weiss WA. PMID: 36264168; PMCID: PMC9812901.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    7. Regulation of eIF4E guides a unique translational program to control erythroid maturation. Sci Adv. 2022 Dec 23; 8(51):eadd3942. Forester CM, Oses-Prieto JA, Phillips NJ, Miglani S, Pang X, Byeon GW, DeMarco R, Burlingame A, Barna M, Ruggero D. PMID: 36563140; PMCID: PMC9788769.
      View in: PubMed   Mentions: 1     Fields:    
    8. Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3. Nat Chem. 2022 12; 14(12):1443-1450. Wang HY, Yang H, Holm M, Tom H, Oltion K, Al-Khdhairawi AAQ, Weber JF, Blanchard SC, Ruggero D, Taunton J. PMID: 36123449; PMCID: PMC10018702.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    9. A tRF nucleator for Nucleolin in cancer metastasis. Mol Cell. 2022 07 21; 82(14):2536-2538. Xu Y, Ruggero D. PMID: 35868253.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. The promises and pitfalls of specialized ribosomes. Mol Cell. 2022 06 16; 82(12):2179-2184. Barna M, Karbstein K, Tollervey D, Ruggero D, Brar G, Greer EL, Dinman JD. PMID: 35714581; PMCID: PMC10228420.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    11. Localization of a TORC1-eIF4F translation complex during CD8+ T cell activation drives divergent cell fate. Mol Cell. 2022 07 07; 82(13):2401-2414.e9. Liedmann S, Liu X, Guy CS, Crawford JC, Rodriguez DA, Kuzuoglu-Öztürk D, Guo A, Verbist KC, Temirov J, Chen MJ, Ruggero D, Zhang H, Thomas PG, Green DR. PMID: 35597236; PMCID: PMC9271638.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    12. Protein synthesis control in cancer: selectivity and therapeutic targeting. EMBO J. 2022 04 19; 41(8):e109823. Kovalski JR, Kuzuoglu-Ozturk D, Ruggero D. PMID: 35315941; PMCID: PMC9016353.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    13. ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance. Cell. 2021 09 30; 184(20):5215-5229.e17. Xu Y, Huangyang P, Wang Y, Xue L, Devericks E, Nguyen HG, Yu X, Oses-Prieto JA, Burlingame AL, Miglani S, Goodarzi H, Ruggero D. PMID: 34559986; PMCID: PMC8547373.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    14. A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies. Dev Cell. 2021 07 26; 56(14):2089-2102.e11. Tiu GC, Kerr CH, Forester CM, Krishnarao PS, Rosenblatt HD, Raj N, Lantz TC, Zhulyn O, Bowen ME, Shokat L, Attardi LD, Ruggero D, Barna M. PMID: 34242585; PMCID: PMC8319123.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    15. Releasing the brake on protein synthesis in hematopoietic stem cells. Cell Stem Cell. 2021 07 01; 28(7):1183-1185. Forester CM, Ruggero D. PMID: 34214436.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Cell Rep. 2021 06 29; 35(13):109321. Kuzuoglu-Ozturk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang GG, Worland ST, Brenner SE, Goodarzi H, Gilbert LA, Ruggero D. PMID: 34192540; PMCID: PMC8323864.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    17. Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function. iScience. 2021 Jul 23; 24(7):102748. Chiu H, Buono R, Jackson LV, Herzog LO, Mallya S, Conn CS, Ruggero D, Fruman DA. PMID: 34278258; PMCID: PMC8261676.
      View in: PubMed   Mentions: 6  
    18. OMIC-03. TRANSLATIONAL CONTROL IN MYC AND MYCN MEDULLOBLASTOMA. Neuro-Oncology. 2021 Jun 1; 23(Suppl 1):i37-i37. Schmidt SC, Navickas NA, Zindy ZF, Farmer FD, Ruggero RD, Goodarzi GH, Roussel RM, Schwer SB, Weiss WW. .
      View in: Publisher Site   Mentions:
    19. The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity. Nat Metab. 2021 02; 3(2):244-257. Conn CS, Yang H, Tom HJ, Ikeda K, Oses-Prieto JA, Vu H, Oguri Y, Nair S, Gill RM, Kajimura S, DeBerardinis RJ, Burlingame AL, Ruggero D. PMID: 33619378; PMCID: PMC10350339.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    20. Examining Myc-Dependent Translation Changes in Cellular Homeostasis and Cancer. Methods Mol Biol. 2021; 2318:255-266. Kovalski JR, Xu Y, Ruggero D. PMID: 34019295.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies. J Nucl Med. 2021 07 01; 62(7):949-955. Zhao N, Huang Y, Wang YH, Muir RK, Chen YC, Wei J, Hooshdaran N, Viswanath P, Seo Y, Ruggero D, Renslo AR, Evans MJ. PMID: 33246980; PMCID: PMC8882888.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    22. Abstract IA17: Strategies to target the mTORC1/eIF4F axis in B-cell leukemia and lymphoma. Molecular Cancer Research. 2020 Oct 1; 18(10_Supplement):ia17-ia17. Herzog HL, Lee LB, Vo VT, Chiu CH, Mallya MS, Fung FA, Singh SM, Aggen AJ, Tibrewal TN, Smith SJ, Wildes WD, Ronai RZ, Ruggero RD, Fruman FD. .
      View in: Publisher Site   Mentions:
    23. An Analysis of Isoclonal Antibody Formats Suggests a Role for Measuring PD-L1 with Low Molecular Weight PET Radiotracers. Mol Imaging Biol. 2020 12; 22(6):1553-1561. Wei J, Wang YH, Lee CY, Truillet C, Oh DY, Xu Y, Ruggero D, Flavell RR, VanBrocklin HF, Seo Y, Craik CS, Fong L, Wang CI, Evans MJ. PMID: 32813112; PMCID: PMC7669684.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    24. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020 07; 583(7816):459-468. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, García-Sastre A, Shokat KM, Shoichet BK, Krogan NJ. PMID: 32353859; PMCID: PMC7431030.
      View in: PubMed   Mentions: 2284     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    25. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. bioRxiv. 2020 Mar 22. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Naing ZZC, Zhou Y, Peng S, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Shen W, Shi Y, Zhang Z, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Ramachandran R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Lin Y, Wankowicz SA, Bohn M, Trenker R, Young JM, Cavero D, Hiatt J, Roth T, Rathore U, Subramanian A, Noack J, Hubert M, Roesch F, Vallet T, Meyer B, White KM, Miorin L, Agard D, Emerman M, Ruggero D, García-Sastre A, Jura N, von Zastrow M, Taunton J, Schwartz O, Vignuzzi M, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor S, Fraser JS, Gross J, Sali A, Kortemme T, Beltrao P, Shokat K, Shoichet BK, Krogan NJ. PMID: 32511329; PMCID: PMC7239059.
      View in: PubMed   Mentions: 28  
    26. The Role of Translation Control in Tumorigenesis and Its Therapeutic Implications. Annual Review of Cancer Biology. 2020 Mar 4; 4(1):1-21. Xu XY, Ruggero RD. .
      View in: Publisher Site   Mentions:
    27. Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling. Mol Cell Proteomics. 2020 02; 19(2):294-307. Wei J, Leung K, Truillet C, Ruggero D, Wells JA, Evans MJ. PMID: 31792071; PMCID: PMC7000124.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    28. Regulation of eIF4E Guides a Unique Translational Program to Steer Erythroid Maturation. Blood. 2019 Nov 13; 134(Supplement_1):156-156. Forester FC, Woo-Byeon WG, Oses-Prieto OJ, Burlingame BA, Barna BM, Ruggero RD. .
      View in: Publisher Site   Mentions:
    29. A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS. Elife. 2019 09 03; 8. McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, Ruggero D. PMID: 31478838; PMCID: PMC6776443.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    30. Author Correction: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nat Cell Biol. 2019 Aug; 21(8):1052. Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salinas CS, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, Fuchs SY, Diehl JA, Ruggero D, Koumenis C. PMID: 31316187.
      View in: PubMed   Mentions: 3     Fields:    
    31. Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. Mol Cell. 2019 09 05; 75(5):967-981.e9. Fish L, Navickas A, Culbertson B, Xu Y, Nguyen HCB, Zhang S, Hochman M, Okimoto R, Dill BD, Molina H, Najafabadi HS, Alarcón C, Ruggero D, Goodarzi H. PMID: 31300274; PMCID: PMC6731133.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    32. ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nat Cell Biol. 2019 07; 21(7):889-899. Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salas Salinas C, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, Fuchs SY, Diehl JA, Ruggero D, Koumenis C. PMID: 31263264; PMCID: PMC6608727.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    33. Translational Control in Cancer. Cold Spring Harb Perspect Biol. 2019 07 01; 11(7). Robichaud N, Sonenberg N, Ruggero D, Schneider RJ. PMID: 29959193; PMCID: PMC6601465.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    34. Measuring Dynamic Changes in the Labile Iron Pool in Vivo with a Reactivity-Based Probe for Positron Emission Tomography. ACS Cent Sci. 2019 Apr 24; 5(4):727-736. Muir RK, Zhao N, Wei J, Wang YH, Moroz A, Huang Y, Chen YC, Sriram R, Kurhanewicz J, Ruggero D, Renslo AR, Evans MJ. PMID: 31041393; PMCID: PMC6487455.
      View in: PubMed   Mentions: 19  
    35. A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis. Cell Host Microbe. 2019 03 13; 25(3):454-462.e6. Moss SM, Taylor IR, Ruggero D, Gestwicki JE, Shokat KM, Mukherjee S. PMID: 30827827; PMCID: PMC6529236.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    36. Translation control of the immune checkpoint in cancer and its therapeutic targeting. Nat Med. 2019 02; 25(2):301-311. Xu Y, Poggio M, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, Xue L, Devericks E, So L, Nguyen HG, Griselin A, Gordan JD, Umetsu SE, Reich SH, Worland ST, Asthana S, Barna M, Webster KR, Cunningham JT, Ruggero D. PMID: 30643286; PMCID: PMC6613562.
      View in: PubMed   Mentions: 113     Fields:    Translation:AnimalsCells
    37. The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes. J Immunol. 2019 01 15; 202(2):579-590. Chiu H, Jackson LV, Oh KI, Mai A, Ronai ZA, Ruggero D, Fruman DA. PMID: 30530594; PMCID: PMC6324996.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    38. A Translation Tuning HuDdle for Neurons. Mol Cell. 2018 07 19; 71(2):195-196. McMahon M, Ruggero D. PMID: 30028999.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    39. A wobbly road to drug resistance in melanoma: tRNA-modifying enzymes in translation reprogramming. EMBO J. 2018 08 01; 37(15). McMahon M, Ruggero D. PMID: 29967029; PMCID: PMC6068441.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    40. Abstract 3694: Measuring oncogene signaling with transferrin-based PET: From bench to bedside. Clinical Research (Excluding Clinical Trials). 2018 Jul 1; 3694-3694. Evans EM, Truillet TC, Ruggero RD, Lewis LJ, Aggarwal AR, Behr BS. .
      View in: Publisher Site   Mentions:
    41. Development of a stress response therapy targeting aggressive prostate cancer. Sci Transl Med. 2018 05 02; 10(439). Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D. PMID: 29720449; PMCID: PMC6045425.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    42. Revealing nascent proteomics in signaling pathways and cell differentiation. Proc Natl Acad Sci U S A. 2018 03 06; 115(10):2353-2358. Forester CM, Zhao Q, Phillips NJ, Urisman A, Chalkley RJ, Oses-Prieto JA, Zhang L, Ruggero D, Burlingame AL. PMID: 29467287; PMCID: PMC5877968.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    43. Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase. Cancer Cell. 2018 01 08; 33(1):91-107.e6. Gwinn DM, Lee AG, Briones-Martin-Del-Campo M, Conn CS, Simpson DR, Scott AI, Le A, Cowan TM, Ruggero D, Sweet-Cordero EA. PMID: 29316436; PMCID: PMC5761662.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    44. A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival. Nat Cell Biol. 2018 01; 20(1):104-115. Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA. PMID: 29230015; PMCID: PMC5741512.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    45. CSIG-42. UNDERSTANDING THE ROLE OF TRANSLATIONAL CONTROL IN MYCN-DRIVEN MEDULLOBLASTOMA. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi58-vi58. Aksoy AO, Fan FQ, Shokat SK, Ruggero RD, Weiss WW. .
      View in: Publisher Site   Mentions:
    46. New frontiers in translational control of the cancer genome. Nat Rev Cancer. 2017 04 24; 17(5):332. Truitt ML, Ruggero D. PMID: 28436470.
      View in: PubMed   Mentions: 32     Fields:    
    47. Editorial overview: Cell regulation: 1000 Flavors including chocolate and chili peppers. Curr Opin Cell Biol. 2017 04; 45:iv-vi. Ruggero D, Shaw RJ. PMID: 28641761.
      View in: PubMed   Mentions:    Fields:    
    48. Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development. Translation Control: an Adaptive Response to Oncogenic Cellular Stress. 2017 Mar 15; a25-a25. Conn CC, Nguyen NH, Kye KY, Cunningham CJ, Truillet TC, Evans EM, Huynh HT, Walters WP, Ruggero RD. .
      View in: Publisher Site   Mentions:
    49. Abstract B11: Oncogenic KRAS regulates 4E-BP1, a repressor of cap-dependent translation, independently of growth factor activity. Translation Control: an Adaptive Response to Oncogenic Cellular Stress. 2017 Mar 15; b11-b11. Silva SJ, Bagni BR, Ruggero RD, McCormick MF. .
      View in: Publisher Site   Mentions:
    50. Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin. Clin Cancer Res. 2017 Jun 15; 23(12):3045-3052. Truillet C, Cunningham JT, Parker MFL, Huynh LT, Conn CS, Ruggero D, Lewis JS, Evans MJ. PMID: 28007777; PMCID: PMC5474159.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    51. The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes. Sci Signal. 2016 05 31; 9(430):ra57. So L, Lee J, Palafox M, Mallya S, Woxland CG, Arguello M, Truitt ML, Sonenberg N, Ruggero D, Fruman DA. PMID: 27245614; PMCID: PMC4924540.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    52. New frontiers in translational control of the cancer genome. Nat Rev Cancer. 2016 04 26; 16(5):288-304. Truitt ML, Ruggero D. PMID: 27112207; PMCID: PMC5491099.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansCells
    53. Automated High-Throughput Quantification Reveals Morphological Heterogeneity in Mammalian Cell Populations. Biophysical Journal. 2016 Feb 1; 110(3):317a. Chang CA, Chen CS, Truitt TM, Ruggero RD, Marshall MW. .
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    54. A Tailor-Made Protein Synthesis Program Drives Erythroid Development and Disease. Blood. 2015 Dec 3; 126(23):3581-3581. Forester FC, Shi SZ, Barna BM, Ruggero RD. .
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    55. Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors. Sci Signal. 2015 Nov 17; 8(403):ra116. Hsieh AC, Nguyen HG, Wen L, Edlind MP, Carroll PR, Kim W, Ruggero D. PMID: 26577921; PMCID: PMC4739654.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    56. Abstract PR07: Myc-dependent translation makes an impact: Tailor-made protein expression for cancer development. Therapeutic Translation. 2015 Oct 1; pr07-pr07. Stumpf SC, Cunningham CT, Ruggero RD. .
      View in: Publisher Site   Mentions:
    57. Differential Requirements for eIF4E Dose in Normal Development and Cancer. Cell. 2015 Jul 02; 162(1):59-71. Truitt ML, Conn CS, Shi Z, Pang X, Tokuyasu T, Coady AM, Seo Y, Barna M, Ruggero D. PMID: 26095252; PMCID: PMC4491046.
      View in: PubMed   Mentions: 183     Fields:    Translation:AnimalsCells
    58. Enhanced MET Translation and Signaling Sustains K-Ras-Driven Proliferation under Anchorage-Independent Growth Conditions. Cancer Res. 2015 Jul 15; 75(14):2851-62. Fujita-Sato S, Galeas J, Truitt M, Pitt C, Urisman A, Bandyopadhyay S, Ruggero D, McCormick F. PMID: 25977330; PMCID: PMC4506276.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    59. YB-1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence. Oncotarget. 2015 Apr 10; 6(10):7470-80. Sheridan CM, Grogan TR, Nguyen HG, Galet C, Rettig MB, Hsieh AC, Ruggero D. PMID: 25797255; PMCID: PMC4480693.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    60. Targeting the eIF4F translation initiation complex: a critical nexus for cancer development. Cancer Res. 2015 Jan 15; 75(2):250-63. Pelletier J, Graff J, Ruggero D, Sonenberg N. PMID: 25593033; PMCID: PMC4299928.
      View in: PubMed   Mentions: 190     Fields:    Translation:HumansAnimals
    61. 38 Molecular Basis of Prostate Cancer. . 2015 Jan 1; (CA Cancer J Clin 62 2012):549-560.e1. Li LL, Hsieh HA, Ruggero RD, Greene GK, Carroll CP. .
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    62. Early Hematopoietic Progenitors of Dkc1 Hypomorphic Mutant Mice Display Decreased Proliferation Rate and an Impaired Control of Serine/Arginine-Rich Splicing Factor 4 (Srsf4) Translation. Blood. 2014 Dec 6; 124(21):2937-2937. Lucena-Araujo LA, Santana-Lemos SB, Thome TC, Ferreira FG, Ruggero RD, Faça FV, Rego RE. .
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    63. Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease. Wiley Interdiscip Rev RNA. 2015 Mar-Apr; 6(2):173-89. McMahon M, Contreras A, Ruggero D. PMID: 25363811; PMCID: PMC4390053.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    64. Marrow failure: a window into ribosome biology. Blood. 2014 Oct 30; 124(18):2784-92. Ruggero D, Shimamura A. PMID: 25237201; PMCID: PMC4215310.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    65. Protein and Nucleotide Biosynthesis Are Coupled by a Single Rate-Limiting Enzyme, PRPS2, to Drive Cancer. Cell. 2014 Jul 1; 158(3):689. Cunningham CJ, Moreno MM, Lodi LA, Ronen RS, Ruggero RD. .
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    66. Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer. Cell. 2014 May 22; 157(5):1088-103. Cunningham JT, Moreno MV, Lodi A, Ronen SM, Ruggero D. PMID: 24855946; PMCID: PMC4140650.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    67. Tailor made protein synthesis for HSCs. Cell Stem Cell. 2014 Apr 03; 14(4):423-4. Barna M, Ruggero D. PMID: 24702992; PMCID: PMC4071939.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    68. mTOR and Regulation of Translation. Translation and Its Regulation in Cancer Biology and Medicine. 2014 Jan 1; 307-343. Tsukumo TY, Laplante LM, Parsyan PA, Ruggero RD, Fonseca FB. .
      View in: Publisher Site   Mentions:
    69. Parallel measurement of dynamic changes in translation rates in single cells. Nat Methods. 2014 Jan; 11(1):86-93. Han K, Jaimovich A, Dey G, Ruggero D, Meyuhas O, Sonenberg N, Meyer T. PMID: 24213167; PMCID: PMC4039304.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    70. The translational landscape of the mammalian cell cycle. Mol Cell. 2013 Nov 21; 52(4):574-82. Stumpf CR, Moreno MV, Olshen AB, Taylor BS, Ruggero D. PMID: 24120665; PMCID: PMC3959127.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    71. New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization. Cancer Discov. 2013 Oct; 3(10):1099-102. Cunningham JT, Ruggero D. PMID: 24124229; PMCID: PMC3857155.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    72. Abstract A57: Plasticity of the translational landscape during the mammalian cell cycle: Implications and new insights for cancer cell proliferation. Post-Transcriptional Regulation. 2013 Oct 1; a57-a57. Stumpf SC, Moreno MM, Olshen OA, Taylor TB, Ruggero RD. .
      View in: Publisher Site   Mentions:
    73. Abstract A46: Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers. Cancer Signaling Networks. 2013 Oct 1; a46-a46. Pourdehnad PM, Truitt TM, Siddiqi SI, Ducker DG, Shokat SK, Ruggero RD. .
      View in: Publisher Site   Mentions:
    74. Assessing gene-level translational control from ribosome profiling. Bioinformatics. 2013 Dec 01; 29(23):2995-3002. Olshen AB, Hsieh AC, Stumpf CR, Olshen RA, Ruggero D, Taylor BS. PMID: 24048356; PMCID: PMC3834798.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    75. Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11988-93. Pourdehnad M, Truitt ML, Siddiqi IN, Ducker GS, Shokat KM, Ruggero D. PMID: 23803853; PMCID: PMC3718086.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    76. H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation. Cell Rep. 2013 May 30; 3(5):1493-502. Bellodi C, McMahon M, Contreras A, Juliano D, Kopmar N, Nakamura T, Maltby D, Burlingame A, Savage SA, Shimamura A, Ruggero D. PMID: 23707062; PMCID: PMC3857015.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    77. Abstract SY32-04: The translation initiation factor elF2a regulates cytoprotective autophagy in Myc-dependent lymphoma. Molecular and Cellular Biology. 2013 Apr 15; sy32-04-sy32-04. Koumenis KC, Hart HL, Cunningham CT, Dey DS, Tameire TF, Mills MI, Ruggero RD, Diehl DA, Fuchs FS. .
      View in: Publisher Site   Mentions:
    78. Common variable immunodeficiency as the initial presentation of dyskeratosis congenita. J Allergy Clin Immunol. 2013 Jul; 132(1):223-6. Allenspach EJ, Bellodi C, Jeong D, Kopmar N, Nakamura T, Ochs HD, Ruggero D, Skoda-Smith S, Shimamura A, Torgerson TR. PMID: 23403051; PMCID: PMC4560355.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    79. Translational control in cancer etiology. Cold Spring Harb Perspect Biol. 2013 Feb 01; 5(2). Ruggero D. PMID: 22767671; PMCID: PMC3552512.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansCells
    80. Investigating Myc-dependent translational regulation in normal and cancer cells. Methods Mol Biol. 2013; 1012:201-12. Cunningham JT, Pourdehnad M, Stumpf CR, Ruggero D. PMID: 24006066; PMCID: PMC4390065.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    81. Exaggerated translation causes synaptic and behavioural aberrations associated with autism. Nature. 2013 Jan 17; 493(7432):411-5. Santini E, Huynh TN, MacAskill AF, Carter AG, Pierre P, Ruggero D, Kaphzan H, Klann E. PMID: 23263185; PMCID: PMC3548017.
      View in: PubMed   Mentions: 200     Fields:    Translation:AnimalsCells
    82. Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature. 2013 Jan 17; 493(7432):371-7. Gkogkas CG, Khoutorsky A, Ran I, Rampakakis E, Nevarko T, Weatherill DB, Vasuta C, Yee S, Truitt M, Dallaire P, Major F, Lasko P, Ruggero D, Nader K, Lacaille JC, Sonenberg N. PMID: 23172145; PMCID: PMC4133997.
      View in: PubMed   Mentions: 271     Fields:    Translation:AnimalsCells
    83. ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. J Clin Invest. 2012 Dec; 122(12):4621-34. Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Thomas-Tikhonenko A, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C. PMID: 23143306; PMCID: PMC3533536.
      View in: PubMed   Mentions: 205     Fields:    Translation:HumansAnimalsCells
    84. Translational Control in Cancer Etiology. Cold Spring Harbor Perspectives in Biology. 2012 Nov 1; 4(11):a015891. Ruggero RD. .
      View in: Publisher Site   Mentions:
    85. IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. Science. 2012 Nov 09; 338(6108):818-22. Upton JP, Wang L, Han D, Wang ES, Huskey NE, Lim L, Truitt M, McManus MT, Ruggero D, Goga A, Papa FR, Oakes SA. PMID: 23042294; PMCID: PMC3742121.
      View in: PubMed   Mentions: 318     Fields:    Translation:HumansAnimalsCells
    86. Revisiting the nucleolus: from marker to dynamic integrator of cancer signaling. Sci Signal. 2012 Sep 11; 5(241):pe38. Ruggero D. PMID: 22969157; PMCID: PMC4390046.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    87. Abstract 2347: Translational control and lung cancer: eIF4F activation promotes tumorigenesis in vivo. Tumor Biology. 2012 Apr 15; 2347-2347. McCauley MJ, Evenson EK, Truitt TM, Kratzke KR, Polunovsky PV, Ruggero RD, BItterman BP, D'Cunha DJ. .
      View in: Publisher Site   Mentions:
    88. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 2012 Feb 22; 485(7396):55-61. Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, Weissman JS, Shokat KM, Rommel C, Ruggero D. PMID: 22367541; PMCID: PMC3663483.
      View in: PubMed   Mentions: 720     Fields:    Translation:HumansAnimalsCells
    89. The “Fifth” RNA Nucleotide: A Role for Ribosomal RNA Pseudouridylation in Control of Gene Expression at the Translational Level. Biophysical approaches to translational control of gene expression. 2012 Jan 1; 253-288. McMahon MM, Bellodi BC, Ruggero RD. .
      View in: Publisher Site   Mentions:
    90. rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells. Mol Cell. 2011 Nov 18; 44(4):660-6. Jack K, Bellodi C, Landry DM, Niederer RO, Meskauskas A, Musalgaonkar S, Kopmar N, Krasnykh O, Dean AM, Thompson SR, Ruggero D, Dinman JD. PMID: 22099312; PMCID: PMC3222873.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimalsCells
    91. Oncogenic AKTivation of translation as a therapeutic target. Br J Cancer. 2011 Jul 26; 105(3):329-36. Hsieh AC, Truitt ML, Ruggero D. PMID: 21772331; PMCID: PMC3172900.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    92. The cancerous translation apparatus. Curr Opin Genet Dev. 2011 Aug; 21(4):474-83. Stumpf CR, Ruggero D. PMID: 21543223; PMCID: PMC3481834.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    93. Abstract SY06-02: Activation of the UPR by c-Myc promotes transformation and tumorigenesis via cytoprotective autophagy. Experimental and Molecular Therapeutics. 2011 Apr 15; sy06-02-sy06-02. Koumenis KC, Zhang ZH, Bi BM, Lehman LS, Datta DT, Liu LH, Thomas-Tikhonenko TA, Koong KA, Fuchs FS, Diehl DJ, Ruggero RD. .
      View in: Publisher Site   Mentions:
    94. Abstract 2078: PERK-mediated autophagy promotes Myc-induced transformation and tumorigenesis. Cellular and Molecular Biology. 2011 Apr 15; 2078-2078. Hart HL, Cunningham CT, Datta DT, Liu LH, Koong KA, Fuchs FS, Diehl DJ, Ruggero RD, Koumenis KC. .
      View in: Publisher Site   Mentions:
    95. Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer. Clin Cancer Res. 2010 Oct 15; 16(20):4914-20. Hsieh AC, Ruggero D. PMID: 20702611; PMCID: PMC7539621.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimals
    96. Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis. Cancer Res. 2010 Jul 15; 70(14):6026-35. Bellodi C, Krasnykh O, Haynes N, Theodoropoulou M, Peng G, Montanaro L, Ruggero D. PMID: 20587522; PMCID: PMC2913864.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimals
    97. Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita. EMBO J. 2010 Jun 02; 29(11):1865-76. Bellodi C, Kopmar N, Ruggero D. PMID: 20453831; PMCID: PMC2885924.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    98. Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. Cancer Cell. 2010 Mar 16; 17(3):249-61. Hsieh AC, Costa M, Zollo O, Davis C, Feldman ME, Testa JR, Meyuhas O, Shokat KM, Ruggero D. PMID: 20227039; PMCID: PMC2901095.
      View in: PubMed   Mentions: 256     Fields:    Translation:AnimalsCells
    99. The role of Myc-induced protein synthesis in cancer. Cancer Res. 2009 Dec 01; 69(23):8839-43. Ruggero D. PMID: 19934336; PMCID: PMC2880919.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    100. Kaplan et al. reply. Nature. 2009 Sep 1; 461(7262):e5-e5. Kaplan KR, Riba RR, Zacharoulis ZS, Bramley BA, Vincent VL, Costa CC, MacDonald MD, Jin JD, Shido SK, Kerns KS, Zhu ZZ, Hicklin HD, Wu WY, Port PJ, Altorki AN, Port PE, Ruggero RD, Shmelkov SS, Jensen JK, Rafii RS, Lyden LD, Wels WJ. .
      View in: Publisher Site   Mentions:
    101. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 2009 Feb 10; 7(2):e38. Feldman ME, Apsel B, Uotila A, Loewith R, Knight ZA, Ruggero D, Shokat KM. PMID: 19209957; PMCID: PMC2637922.
      View in: PubMed   Mentions: 587     Fields:    Translation:AnimalsCells
    102. Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency. Nature. 2008 Dec 18; 456(7224):971-5. Barna M, Pusic A, Zollo O, Costa M, Kondrashov N, Rego E, Rao PH, Ruggero D. PMID: 19011615; PMCID: PMC2880952.
      View in: PubMed   Mentions: 244     Fields:    Translation:AnimalsCells
    103. 130 INVITED Novel insight into the pathogenesis of dyskeratosis congenita: how defective ribosome activity can cause cancer and disease. European Journal of Cancer Supplements. 2007 Sep 1; 5(4):35-36. Ruggero RD, Yoon YA, Peng PG, Zollo ZO, Adamo AR, Haynes HN, Xu XW, Rego RE. .
      View in: Publisher Site   Mentions:
    104. Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita. Science. 2006 May 12; 312(5775):902-6. Yoon A, Peng G, Brandenburger Y, Brandenburg Y, Zollo O, Xu W, Rego E, Ruggero D. PMID: 16690864.
      View in: PubMed   Mentions: 230     Fields:    Translation:HumansAnimalsCells
    105. Leukemia with distinct phenotypes in transgenic mice expressing PML/RAR alpha, PLZF/RAR alpha or NPM/RAR alpha. Oncogene. 2006 Mar 23; 25(13):1974-9. Rego EM, Ruggero D, Tribioli C, Cattoretti G, Kogan S, Redner RL, Pandolfi PP. PMID: 16331271.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    106. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature. 2005 Dec 08; 438(7069):820-7. Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. PMID: 16341007; PMCID: PMC2945882.
      View in: PubMed   Mentions: 1361     Fields:    Translation:HumansAnimalsCells
    107. The Akt of translational control. Oncogene. 2005 Nov 14; 24(50):7426-34. Ruggero D, Sonenberg N. PMID: 16288289.
      View in: PubMed   Mentions: 93     Fields:    Translation:Cells
    108. The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. Nat Med. 2004 May; 10(5):484-6. Ruggero D, Montanaro L, Ma L, Xu W, Londei P, Cordon-Cardo C, Pandolfi PP. PMID: 15098029.
      View in: PubMed   Mentions: 258     Fields:    Translation:Animals
    109. Does the ribosome translate cancer? Nat Rev Cancer. 2003 Mar; 3(3):179-92. Ruggero D, Pandolfi PP. PMID: 12612653.
      View in: PubMed   Mentions: 423     Fields:    Translation:Cells
    110. Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification. Science. 2003 Jan 10; 299(5604):259-62. Ruggero D, Grisendi S, Piazza F, Rego E, Mari F, Rao PH, Cordon-Cardo C, Pandolfi PP. PMID: 12522253.
      View in: PubMed   Mentions: 202     Fields:    Translation:AnimalsCells
    111. The puzzling multiple lives of PML and its role in the genesis of cancer. Bioessays. 2000 Sep; 22(9):827-35. Ruggero D, Wang ZG, Pandolfi PP. PMID: 10944585.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    112. Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. J Exp Med. 2000 Feb 21; 191(4):631-40. Zhong S, Salomoni P, Ronchetti S, Guo A, Ruggero D, Pandolfi PP. PMID: 10684855; PMCID: PMC2195846.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    113. Cis-acting signals controlling translational initiation in the thermophilic archaeon Sulfolobus solfataricus. Mol Microbiol. 1999 Oct; 34(2):377-84. Condò I, Ciammaruconi A, Benelli D, Ruggero D, Londei P. PMID: 10564480.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    114. PML is essential for multiple apoptotic pathways. Nat Genet. 1998 Nov; 20(3):266-72. Wang ZG, Ruggero D, Ronchetti S, Zhong S, Gaboli M, Rivi R, Pandolfi PP. PMID: 9806545.
      View in: PubMed   Mentions: 155     Fields:    Translation:AnimalsCells
    115. A novel aminopeptidase associated with the 60 kDa chaperonin in the thermophilic archaeon Sulfolobus solfataricus. Mol Microbiol. 1998 Aug; 29(3):775-85. Condò I, Ruggero D, Reinhardt R, Londei P. PMID: 9723917.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    116. The chaperonin of the archaeon Sulfolobus solfataricus is an RNA-binding protein that participates in ribosomal RNA processing. EMBO J. 1998 Jun 15; 17(12):3471-7. Ruggero D, Ciammaruconi A, Londei P. PMID: 9628882; PMCID: PMC1170683.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    117. Differential antibiotic sensitivity determined by the large ribosomal subunit in thermophilic archaea. J Bacteriol. 1996 Jun; 178(11):3396-8. Ruggero D, Londei P. PMID: 8655531; PMCID: PMC178103.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    118. In vitro translation of archaeal natural mRNAs at high temperature. FEMS Microbiology Letters. 1993 Feb 1; 107(1):89-94. Ruggero RD, Creti CR, Londei LP. .
      View in: Publisher Site   Mentions:
    119. Lithium and granulocytopenia during induction treatment of adult acute lymphoblastic leukemia. Tumori. 1982 Oct 31; 68(5):427-30. Bandini G, Ricci P, Ruggero D, Cantore M, Visani G, Tura S. PMID: 6960590.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    120. Treatment of severe aplastic anaemia with antilymphocyte globulin or bone-marrow transplantation. Br Med J (Clin Res Ed). 1981 Mar 14; 282(6267):860-3. Speck B, Gratwohl A, Nissen C, Leibundgut U, Ruggero D, Osterwalder B, Burri HP, Cornu P, Jeannet M. PMID: 6783204; PMCID: PMC1504686.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    121. [Experience with intensive plasma exchange]. Schweiz Med Wochenschr. 1980 Oct 04; 110(40):1449-51. Gratwohl A, Cornu P, Nissen C, Ruggero D, Osterwalder B, Speck B. PMID: 7280593.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    122. Serum lysozyme level in adult acute non-lymphoid leukaemia. Haematologica. 1979 Jun; 64(3):288-95. Bandini G, Ricci P, Baccarani M, Ruggero D, Tura S. PMID: 113297.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    123. Adult acute lymphoblastic leukaemia: study of 32 patients and analysis of prognostic factors. Scand J Haematol. 1979 Feb; 22(2):154-64. Ruggero D, Baccarani M, Gobbi M, Tura S. PMID: 311937.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    124. Sex and prognosis in adult acute lymphoblastic leukaemia. Br Med J. 1978 Dec 09; 2(6152):1646. Baccarani M, Ruggero D, Gobbi M, Tura S. PMID: 281982; PMCID: PMC1608841.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    125. Ph1-positive chronic myeloid leukaemia presenting in blastic crisis: report of 12 cases. Boll Ist Sieroter Milan. 1978 Jul 31; 57(3):383-91. Zaccaria A, Ruggero D, Guolo ML, Guarini A, Frezza R, Baccarani M, Tura S. PMID: 282907.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    126. Immunotherapy with BCG and leukemic blast cells during complete remission of acute myeloid leukemia. Haematologica. 1977 Oct; 62(5):529-36. Gobbi M, Ruggero D, Baccarani M, Zaccaria A, Tomasini I, Tura S. PMID: 412739.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    127. Nervous system involvement in adult acute myeloid leukaemia: report of five cases. Haematologica. 1977 Jun; 62(3):312-9. Ruggero D, Baccarani M, Zaccaria A, Gobbi M, Tomasini I, Tura S. PMID: 408244.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    128. Immunological study of patients with Hodgkin's disease in long-lasting not-maintained complete remission. Boll Ist Sieroter Milan. 1977 Mar 31; 56(2):144-51. Gobbi M, Fiacchini M, Tomasini I, Ruggero D, Lauria F, Tura S. PMID: 326273.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    129. Acute promyelocytic leukemia: results of therapy and analysis of 13 cases. Acta Haematol. 1977; 58(2):108-19. Ruggero D, Baccarani M, Guarini A, Gugliotta L, Gobbi M, Ricci P, Zaccaria A, Lauria F, Tomasini I, Fiacchini M, Santucci MA, Tura S. PMID: 409019.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    130. [Progress and problems in the treatment of acute myeloid leukemia: analysis of 92 cases]. G Clin Med. 1976 Sep-Oct; 57(9-10):283-97. Ruggero D, Baccarani M, Tomasini I, Gobbi M, Santucci MA, Guarini A, Tura S. PMID: 1072018.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    131. ["Cured" Hodgkin's disease in a retrospective study of 147 cases]. G Clin Med. 1976 Mar-Aug; 57(5-6):167-82. Fiacchini M, Ruggero D, Tomasini I, Sciascia R, Emiliani E, Babini L. PMID: 1010166.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    132. [Antibiotic therapy in the high risk patient (hematologic study)]. G Clin Med. 1976 Mar-Apr; 57(3-4):92-104. Tura S, Ruggero D. PMID: 1001857.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    133. A simultaneous study of bone marrow, spleen, and liver in chronic myeloid leukemia: evidence for differences in cell composition and karyotypes. Ser Haematol. 1975; 8(4):81-112. Baccarani M, Zaccaria A, Santucci AM, Bagnara GP, Ricci P, Gobbi M, Ruggero D, Brunelli MA, Tura S. PMID: 1071286.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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