Andrei Goga, MD, PhD

Title(s)Professor, Cell and Tissue Biology
SchoolSchool of Dentistry
Address513 Parnassus Avenue, HSW, #760
San Francisco CA 94143
Phone415-476-4191
PronounsHe/Him/His
ORCID ORCID Icon0000-0001-9127-0986 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoMedical Oncology Fellowship2003School of Medicine
    University of California, San Francisco Residency School of Medicine
    University of California Los AngelesM.D., Ph.D.1997School of Medicine
    Collapse Awards and Honors
    2011American Society for Clinical Investigations
    2012CDMRP Era of Hope Scholar
    2009V-Foundation Scholar
    2012Leukemia and Lymphoma Society Scholar
    2008Susan G. Komen Scholar Award
    2005NCI K08 Mentored-Physician Scientist Award
    2001HHMI Physician-Scientist Fellowship Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Understanding breast cancer progression as a defect in the mechanics of tissue self-organization
    NIH U01CA244109May 1, 2020 - Apr 30, 2025
    Role: Co-Principal Investigator
    Uncovering Mechanisms of Regulation and Dependency on Fatty Acid Oxidation in MYC-Driven Tumors
    NIH R01CA223817Jul 3, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Integrative approach to heterogeneity in breast cancer metastasis
    NIH U01CA199315Jun 1, 2016 - May 31, 2021
    Role: Principal Investigator
    In Vivo Metabolic Catastrophe Is Induced By Acute Oncogene Inhibition (PQ #22)
    NIH R01CA170447Aug 1, 2012 - May 31, 2018
    Role: Principal Investigator
    Targeting the MYC Oncogene with CDK Inhibitors
    NIH R01CA136717Apr 19, 2010 - Jan 31, 2017
    Role: Principal Investigator
    CDK Inhibition in Cancer
    NIH K08CA104032Aug 1, 2005 - Jul 31, 2011
    Role: Principal Investigator
    Molecular and Cellular Mechanisms in Cancer
    NIH T32CA108462Sep 1, 2004 - Aug 31, 2025
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway. Cell Rep Med. 2025 Feb 18; 6(2):101941. Park JH, Jung KH, Jia D, Yang S, Attri KS, Ahn S, Murthy D, Samanta T, Dutta D, Ghidey M, Chatterjee S, Han SY, Pedroza DA, Tiwari A, Lee JV, Davis C, Li S, Putluri V, Creighton CJ, Putluri N, Dobrolecki LE, Lewis MT, Rosen JM, Onuchic JN, Goga A, Kaipparettu BA. PMID: 39933530.
      View in: PubMed   Mentions:    Fields:    
    2. Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling. bioRxiv. 2025 Jan 31. Nakagawa R, Beardsley A, Durney S, Hayward MK, Subramanyam V, Meyer NP, Wismer H, Goodarzi H, Weaver VM, Van de Mark D, Goga A. PMID: 39386679; PMCID: PMC11463411.
      View in: PubMed   Mentions:
    3. Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes. J Clin Invest. 2024 Sep 03; 134(17). Winkler J, Tan W, Diadhiou CM, McGinnis CS, Abbasi A, Hasnain S, Durney S, Atamaniuc E, Superville D, Awni L, Lee JV, Hinrichs JH, Wagner PS, Singh N, Hein MY, Borja M, Detweiler AM, Liu SY, Nanjaraj A, Sitarama V, Rugo HS, Neff N, Gartner ZJ, Oliveira Pisco A, Goga A, Darmanis S, Werb Z. PMID: 39225101; PMCID: PMC11364385.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. The temporal progression of lung immune remodeling during breast cancer metastasis. Cancer Cell. 2024 Jun 10; 42(6):1018-1031.e6. McGinnis CS, Miao Z, Superville D, Yao W, Goga A, Reticker-Flynn NE, Winkler J, Satpathy AT. PMID: 38821060; PMCID: PMC11255555.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    5. Respiratory complex I regulates dendritic cell maturation in explant model of human tumor immune microenvironment. J Immunother Cancer. 2024 Apr 11; 12(4). Turpin R, Liu R, Munne PM, Peura A, Rannikko JH, Philips G, Boeckx B, Salmelin N, Hurskainen E, Suleymanova I, Aung J, Vuorinen EM, Lehtinen L, Mutka M, Kovanen PE, Niinikoski L, Meretoja TJ, Mattson J, Mustjoki S, Saavalainen P, Goga A, Lambrechts D, Pouwels J, Hollmén M, Klefström J. PMID: 38604809; PMCID: PMC11015234.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Changes in spindle morphology driven by TPX2 overexpression in MYC-driven breast cancer cells. MicroPubl Biol. 2024; 2024. Pena G, Rohrberg J, Goga A, Heald R. PMID: 38660563; PMCID: PMC11040394.
      View in: PubMed   Mentions:
    7. The oncogene cyclin D1 promotes bipolar spindle integrity under compressive force. PLoS One. 2024; 19(3):e0296779. Sutanto R, Neahring L, Serra Marques A, Jacobo Jacobo M, Kilinc S, Goga A, Dumont S. PMID: 38478555; PMCID: PMC10936824.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. An inflamed tumor cell subpopulation promotes chemotherapy resistance in triple negative breast cancer. Sci Rep. 2024 02 14; 14(1):3694. Jacobo Jacobo M, Donnella HJ, Sobti S, Kaushik S, Goga A, Bandyopadhyay S. PMID: 38355954; PMCID: PMC10866903.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. The oncogene cyclin D1 promotes bipolar spindle integrity under compressive force. bioRxiv. 2023 May 31. Sutanto R, Neahring L, Marques AS, Kilinc S, Goga A, Dumont S. PMID: 37398487; PMCID: PMC10312523.
      View in: PubMed   Mentions:
    10. An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus. Nat Cell Biol. 2023 06; 25(6):892-903. Navickas A, Asgharian H, Winkler J, Fish L, Garcia K, Markett D, Dodel M, Culbertson B, Miglani S, Joshi T, Yin K, Nguyen P, Zhang S, Stevers N, Hwang HW, Mardakheh F, Goga A, Goodarzi H. PMID: 37156909; PMCID: PMC10264242.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    11. Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer. Nat Commun. 2022 Nov 21; 13(1):7140. Lee JV, Housley F, Yau C, Nakagawa R, Winkler J, Anttila JM, Munne PM, Savelius M, Houlahan KE, Van de Mark D, Hemmati G, Hernandez GA, Zhang Y, Samson S, Baas C, Kok M, Esserman LJ, van 't Veer LJ, Rugo HS, Curtis C, Klefström J, Matloubian M, Goga A. PMID: 36414627; PMCID: PMC9681724.
      View in: PubMed   Mentions:    Fields:    
    12. Deep whole genome sequencing identifies recurrent genomic alterations in commonly used breast cancer cell lines and patient-derived xenograft models. Breast Cancer Res. 2022 09 24; 24(1):63. Deng N, Minoche A, Harvey K, Li M, Winkler J, Goga A, Swarbrick A. PMID: 36153537; PMCID: PMC9509640.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. Host and gut bacteria share metabolic pathways for anti-cancer drug metabolism. Nat Microbiol. 2022 10; 7(10):1605-1620. Spanogiannopoulos P, Kyaw TS, Guthrie BGH, Bradley PH, Lee JV, Melamed J, Malig YNA, Lam KN, Gempis D, Sandy M, Kidder W, Van Blarigan EL, Atreya CE, Venook A, Gerona RR, Goga A, Pollard KS, Turnbaugh PJ. PMID: 36138165; PMCID: PMC9530025.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    14. Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer. Nat Commun. 2022 06 27; 13(1):3671. Lee JV, Housley F, Yau C, Nakagawa R, Winkler J, Anttila JM, Munne PM, Savelius M, Houlahan KE, Van de Mark D, Hemmati G, Hernandez GA, Zhang Y, Samson S, Baas C, Kok M, Esserman LJ, van 't Veer LJ, Rugo HS, Curtis C, Klefström J, Matloubian M, Goga A. PMID: 35760778; PMCID: PMC9237085.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    15. Biomarkers for Cyclin-Dependent Kinase 4/6 Inhibitors in the Treatment of Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Advanced/Metastatic Breast Cancer: Translation to Clinical Practice. JCO Precis Oncol. 2022 06; 6:e2100473. Bui TBV, Burgering BMT, Goga A, Rugo HS, van 't Veer LJ. PMID: 35666959.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability. Nat Chem Biol. 2022 07; 18(7):751-761. Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA. PMID: 35637349; PMCID: PMC9469796.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    17. NCI's publication affiliation conundrum: Reframing innovation to incentivize an equitable path for advocate representation. Transl Oncol. 2022 Feb; 16:101325. Samson S, Northey JJ, Acerbi I, Goga A, Flink CL, Weaver VM, LaBarge MA. PMID: 34974281; PMCID: PMC8728534.
      View in: PubMed   Mentions:
    18. Evaluation of disseminated tumor cells and circulating tumor cells in patients with breast cancer receiving adjuvant zoledronic acid. NPJ Breast Cancer. 2021 Sep 06; 7(1):113. Vidula N, Greenberg S, Petrillo L, Hwang J, Melisko M, Goga A, Moasser M, Magbanua M, Park JW, Rugo HS. PMID: 34489453; PMCID: PMC8421499.
      View in: PubMed   Mentions: 9  
    19. Oncogene-regulated release of extracellular vesicles. Dev Cell. 2021 07 12; 56(13):1989-2006.e6. Kilinc S, Paisner R, Camarda R, Gupta S, Momcilovic O, Kohnz RA, Avsaroglu B, L'Etoile ND, Perera RM, Nomura DK, Goga A. PMID: 34118203; PMCID: PMC8292920.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    20. In Vivo Optical Metabolic Imaging of Long-Chain Fatty Acid Uptake in Orthotopic Models of Triple-Negative Breast Cancer. Cancers (Basel). 2021 Jan 05; 13(1). Madonna MC, Duer JE, Lee JV, Williams J, Avsaroglu B, Zhu C, Deutsch R, Wang R, Crouch BT, Hirschey MD, Goga A, Ramanujam N. PMID: 33466329; PMCID: PMC7794847.
      View in: PubMed   Mentions: 8  
    21. MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinoma. J Hepatol. 2021 01; 74(1):122-134. Komoll RM, Hu Q, Olarewaju O, von Döhlen L, Yuan Q, Xie Y, Tsay HC, Daon J, Qin R, Manns MP, Sharma AD, Goga A, Ott M, Balakrishnan A. PMID: 32738449.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    22. MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities. Cell Rep. 2020 03 10; 30(10):3368-3382.e7. Rohrberg J, Van de Mark D, Amouzgar M, Lee JV, Taileb M, Corella A, Kilinc S, Williams J, Jokisch ML, Camarda R, Balakrishnan S, Shankar R, Zhou A, Chang AN, Chen B, Rugo HS, Dumont S, Goga A. PMID: 32160543; PMCID: PMC7085414.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    23. Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer. Nat Med. 2019 01; 25(1):111-118. Shah KN, Bhatt R, Rotow J, Rohrberg J, Olivas V, Wang VE, Hemmati G, Martins MM, Maynard A, Kuhn J, Galeas J, Donnella HJ, Kaushik S, Ku A, Dumont S, Krings G, Haringsma HJ, Robillard L, Simmons AD, Harding TC, McCormick F, Goga A, Blakely CM, Bivona TG, Bandyopadhyay S. PMID: 30478424; PMCID: PMC6324945.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    24. Cancer cells exploit an orphan RNA to drive metastatic progression. Nat Med. 2018 11; 24(11):1743-1751. Fish L, Zhang S, Yu JX, Culbertson B, Zhou AY, Goga A, Goodarzi H. PMID: 30397354; PMCID: PMC6223318.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    25. microRNA 193a-5p Regulates Levels of Nucleolar- and Spindle-Associated Protein 1 to Suppress Hepatocarcinogenesis. Gastroenterology. 2018 12; 155(6):1951-1966.e26. Roy S, Hooiveld GJ, Seehawer M, Caruso S, Heinzmann F, Schneider AT, Frank AK, Cardenas DV, Sonntag R, Luedde M, Trautwein C, Stein I, Pikarsky E, Loosen S, Tacke F, Ringelhan M, Avsaroglu SK, Goga A, Buendia MA, Vucur M, Heikenwalder M, Zucman-Rossi J, Zender L, Roderburg C, Luedde T. PMID: 30165047; PMCID: PMC6279541.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    26. Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer. Nat Chem Biol. 2018 08; 14(8):768-777. Donnella HJ, Webber JT, Levin RS, Camarda R, Momcilovic O, Bayani N, Shah KN, Korkola JE, Shokat KM, Goga A, Gordan JD, Bandyopadhyay S. PMID: 29942081; PMCID: PMC6051919.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    27. Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity. Nat Commun. 2018 05 23; 9(1):2028. Nguyen QH, Pervolarakis N, Blake K, Ma D, Davis RT, James N, Phung AT, Willey E, Kumar R, Jabart E, Driver I, Rock J, Goga A, Khan SA, Lawson DA, Werb Z, Kessenbrock K. PMID: 29795293; PMCID: PMC5966421.
      View in: PubMed   Mentions: 187     Fields:    Translation:HumansCells
    28. New Horizons in Advocacy Engaged Physical Sciences and Oncology Research. Trends Cancer. 2018 04; 4(4):260-264. Samson S, Northey JJ, Plaks V, Baas C, Dean I, LaBarge MA, Goga A, Van't Veer LJ, Weaver VM. PMID: 29606307; PMCID: PMC6932745.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    29. Comprehensive analysis of normal adjacent to tumor transcriptomes. Nat Commun. 2017 10 20; 8(1):1077. Aran D, Camarda R, Odegaard J, Paik H, Oskotsky B, Krings G, Goga A, Sirota M, Butte AJ. PMID: 29057876; PMCID: PMC5651823.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansCells
    30. Cancer recurrence monitoring using hyperpolarized [1-13C]pyruvate metabolic imaging in murine breast cancer model. Magn Reson Imaging. 2017 11; 43:105-109. Shin PJ, Zhu Z, Camarda R, Bok RA, Zhou AY, Kurhanewicz J, Goga A, Vigneron DB. PMID: 28716678; PMCID: PMC5632580.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    31. In vivo Reprogramming of Cancer Metabolism by MYC. Front Cell Dev Biol. 2017; 5:35. Camarda R, Williams J, Goga A. PMID: 28443280; PMCID: PMC5386977.
      View in: PubMed   Mentions: 33  
    32. Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3121-3126. Kessenbrock K, Smith P, Steenbeek SC, Pervolarakis N, Kumar R, Minami Y, Goga A, Hinck L, Werb Z. PMID: 28270600; PMCID: PMC5373387.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    33. MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. EMBO Rep. 2017 04; 18(4):569-585. Anderton B, Camarda R, Balakrishnan S, Balakrishnan A, Kohnz RA, Lim L, Evason KJ, Momcilovic O, Kruttwig K, Huang Q, Xu G, Nomura DK, Goga A. PMID: 28219903; PMCID: PMC5376764.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    34. Development of high resolution 3D hyperpolarized carbon-13 MR molecular imaging techniques. Magn Reson Imaging. 2017 05; 38:152-162. Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Zhu Z, Chen HY, Bok R, Goga A, Kurhanewicz J, Larson PE, Vigneron DB. PMID: 28077268; PMCID: PMC5360530.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    35. PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression. Nat Med. 2016 11; 22(11):1321-1329. Horiuchi D, Camarda R, Zhou AY, Yau C, Momcilovic O, Balakrishnan S, Corella AN, Eyob H, Kessenbrock K, Lawson DA, Marsh LA, Anderton BN, Rohrberg J, Kunder R, Bazarov AV, Yaswen P, McManus MT, Rugo HS, Werb Z, Goga A. PMID: 27775705; PMCID: PMC5341692.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    36. Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity. ACS Chem Biol. 2016 08 19; 11(8):2131-9. Kohnz RA, Roberts LS, DeTomaso D, Bideyan L, Yan P, Bandyopadhyay S, Goga A, Yosef N, Nomura DK. PMID: 27380425; PMCID: PMC4994060.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    37. GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity. Cell Chem Biol. 2016 05 19; 23(5):567-578. Louie SM, Grossman EA, Crawford LA, Ding L, Camarda R, Huffman TR, Miyamoto DK, Goga A, Weerapana E, Nomura DK. PMID: 27185638; PMCID: PMC4876719.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    38. Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat Med. 2016 04; 22(4):427-32. Camarda R, Zhou AY, Kohnz RA, Balakrishnan S, Mahieu C, Anderton B, Eyob H, Kajimura S, Tward A, Krings G, Nomura DK, Goga A. PMID: 26950360; PMCID: PMC4892846.
      View in: PubMed   Mentions: 277     Fields:    Translation:HumansCells
    39. Fas-Activated Mitochondrial Apoptosis Culls Stalled Embryonic Stem Cells to Promote Differentiation. Curr Biol. 2015 Dec 07; 25(23):3110-8. Wang ES, Reyes NA, Melton C, Huskey NE, Momcilovic O, Goga A, Blelloch R, Oakes SA. PMID: 26585277; PMCID: PMC4703423.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    40. Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. Hum Mol Genet. 2015 Dec 20; 24(25):7421-31. Caswell JL, Camarda R, Zhou AY, Huntsman S, Hu D, Brenner SE, Zaitlen N, Goga A, Ziv E. PMID: 26472073; PMCID: PMC4664170.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    41. Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells. Nature. 2015 Oct 01; 526(7571):131-5. Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z. PMID: 26416748; PMCID: PMC4648562.
      View in: PubMed   Mentions: 469     Fields:    Translation:HumansAnimalsCells
    42. Biogenesis, delivery, and function of extracellular RNA. J Extracell Vesicles. 2015; 4:27494. Patton JG, Franklin JL, Weaver AM, Vickers K, Zhang B, Coffey RJ, Ansel KM, Blelloch R, Goga A, Huang B, L'Etoille N, Raffai RL, Lai CP, Krichevsky AM, Mateescu B, Greiner VJ, Hunter C, Voinnet O, McManus MT. PMID: 26320939; PMCID: PMC4553266.
      View in: PubMed   Mentions: 48     Fields:    
    43. Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish. PLoS Genet. 2015 Jul; 11(7):e1005305. Evason KJ, Francisco MT, Juric V, Balakrishnan S, Lopez Pazmino Mdel P, Gordan JD, Kakar S, Spitsbergen J, Goga A, Stainier DY. PMID: 26134322; PMCID: PMC4489858.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    44. Direct and indirect targeting of MYC to treat acute myeloid leukemia. Cancer Chemother Pharmacol. 2015 Jul; 76(1):35-46. Brondfield S, Umesh S, Corella A, Zuber J, Rappaport AR, Gaillard C, Lowe SW, Goga A, Kogan SC. PMID: 25956709; PMCID: PMC4485702.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    45. Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer. ACS Chem Biol. 2015 Jul 17; 10(7):1624-30. Kohnz RA, Mulvihill MM, Chang JW, Hsu KL, Sorrentino A, Cravatt BF, Bandyopadhyay S, Goga A, Nomura DK. PMID: 25945974; PMCID: PMC4702252.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    46. CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation. Stem Cell Reports. 2015 Mar 10; 4(3):374-89. Huskey NE, Guo T, Evason KJ, Momcilovic O, Pardo D, Creasman KJ, Judson RL, Blelloch R, Oakes SA, Hebrok M, Goga A. PMID: 25733019; PMCID: PMC4375943.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    47. Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map. Cancer Discov. 2015 02; 5(2):154-67. Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakhshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S. PMID: 25501949; PMCID: PMC4407699.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    48. Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma. Blood. 2014 Sep 25; 124(13):2081-90. Hoellein A, Fallahi M, Schoeffmann S, Steidle S, Schaub FX, Rudelius M, Laitinen I, Nilsson L, Goga A, Peschel C, Nilsson JA, Cleveland JL, Keller U. PMID: 25143484; PMCID: PMC4186537.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    49. Inositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness. ACS Chem Biol. 2014 Jun 20; 9(6):1340-50. Benjamin DI, Louie SM, Mulvihill MM, Kohnz RA, Li DS, Chan LG, Sorrentino A, Bandyopadhyay S, Cozzo A, Ohiri A, Goga A, Ng SW, Nomura DK. PMID: 24738946; PMCID: PMC4076040.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    50. Phase I dose-escalation study of 5-day intermittent oral lapatinib therapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer. J Clin Oncol. 2014 May 10; 32(14):1472-9. Chien AJ, Munster PN, Melisko ME, Rugo HS, Park JW, Goga A, Auerback G, Khanafshar E, Ordovas K, Koch KM, Moasser MM. PMID: 24711549; PMCID: PMC4017711.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    51. Taking on challenging targets: making MYC druggable. Am Soc Clin Oncol Educ Book. 2014; e497-502. Horiuchi D, Anderton B, Goga A. PMID: 24857145; PMCID: PMC4892842.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    52. Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discov. 2014 Feb; 4(2):232-45. Balko JM, Giltnane JM, Wang K, Schwarz LJ, Young CD, Cook RS, Owens P, Sanders ME, Kuba MG, Sánchez V, Kurupi R, Moore PD, Pinto JA, Doimi FD, Gómez H, Horiuchi D, Goga A, Lehmann BD, Bauer JA, Pietenpol JA, Ross JS, Palmer GA, Yelensky R, Cronin M, Miller VA, Stephens PJ, Arteaga CL. PMID: 24356096; PMCID: PMC3946308.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansCells
    53. MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer. Hepatology. 2014 Jan; 59(1):202-15. Lim L, Balakrishnan A, Huskey N, Jones KD, Jodari M, Ng R, Song G, Riordan J, Anderton B, Cheung ST, Willenbring H, Dupuy A, Chen X, Brown D, Chang AN, Goga A. PMID: 23913442; PMCID: PMC3877416.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    54. A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis. Elife. 2013 Oct 15; 2:e00822. Olive V, Sabio E, Bennett MJ, De Jong CS, Biton A, McGann JC, Greaney SK, Sodir NM, Zhou AY, Balakrishnan A, Foth M, Luftig MA, Goga A, Speed TP, Xuan Z, Evan GI, Wan Y, Minella AC, He L. PMID: 24137534; PMCID: PMC3796314.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    55. Endogenous nuclear RNAi mediates behavioral adaptation to odor. Cell. 2013 Aug 29; 154(5):1010-1022. Juang BT, Gu C, Starnes L, Palladino F, Goga A, Kennedy S, L'Etoile ND. PMID: 23993094; PMCID: PMC4274153.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    56. Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS. Magn Reson Med. 2014 Jan; 71(1):1-11. Swisher CL, Larson PE, Kruttwig K, Kerr AB, Hu S, Bok RA, Goga A, Pauly JM, Nelson SJ, Kurhanewicz J, Vigneron DB. PMID: 23412881; PMCID: PMC3659200.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    57. HER3 signalling is regulated through a multitude of redundant mechanisms in HER2-driven tumour cells. Biochem J. 2012 Nov 01; 447(3):417-25. Amin DN, Sergina N, Lim L, Goga A, Moasser MM. PMID: 22853430; PMCID: PMC3722874.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    58. IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. Science. 2012 Nov 09; 338(6108):818-22. Upton JP, Wang L, Han D, Wang ES, Huskey NE, Lim L, Truitt M, McManus MT, Ruggero D, Goga A, Papa FR, Oakes SA. PMID: 23042294; PMCID: PMC3742121.
      View in: PubMed   Mentions: 330     Fields:    Translation:HumansAnimalsCells
    59. Dual blockade of lipid and cyclin-dependent kinases induces synthetic lethality in malignant glioma. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12722-7. Cheng CK, Gustafson WC, Charron E, Houseman BT, Zunder E, Goga A, Gray NS, Pollok B, Oakes SA, James CD, Shokat KM, Weiss WA, Fan QW. PMID: 22802621; PMCID: PMC3411950.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    60. Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways. Proc Natl Acad Sci U S A. 2012 Apr 24; 109(17):E1019-27. Horiuchi D, Huskey NE, Kusdra L, Wohlbold L, Merrick KA, Zhang C, Creasman KJ, Shokat KM, Fisher RP, Goga A. PMID: 22474407; PMCID: PMC3340028.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    61. MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. J Exp Med. 2012 Apr 09; 209(4):679-96. Horiuchi D, Kusdra L, Huskey NE, Chandriani S, Lenburg ME, Gonzalez-Angulo AM, Creasman KJ, Bazarov AV, Smyth JW, Davis SE, Yaswen P, Mills GB, Esserman LJ, Goga A. PMID: 22430491; PMCID: PMC3328367.
      View in: PubMed   Mentions: 186     Fields:    Translation:HumansAnimalsCells
    62. Investigating tumor perfusion and metabolism using multiple hyperpolarized (13)C compounds: HP001, pyruvate and urea. Magn Reson Imaging. 2012 Apr; 30(3):305-11. von Morze C, Larson PE, Hu S, Yoshihara HA, Bok RA, Goga A, Ardenkjaer-Larsen JH, Vigneron DB. PMID: 22169407; PMCID: PMC3393100.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    63. 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression. Cell Metab. 2011 Jul 06; 14(1):131-42. Hu S, Balakrishnan A, Bok RA, Anderton B, Larson PE, Nelson SJ, Kurhanewicz J, Vigneron DB, Goga A. PMID: 21723511; PMCID: PMC3858338.
      View in: PubMed   Mentions: 133     Fields:    Translation:AnimalsCells
    64. Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation. Mol Cell. 2011 Jun 10; 42(5):624-36. Merrick KA, Wohlbold L, Zhang C, Allen JJ, Horiuchi D, Huskey NE, Goga A, Shokat KM, Fisher RP. PMID: 21658603; PMCID: PMC3119039.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    65. Nanodiamond therapeutic delivery agents mediate enhanced chemoresistant tumor treatment. Sci Transl Med. 2011 Mar 09; 3(73):73ra21. Chow EK, Zhang XQ, Chen M, Lam R, Robinson E, Huang H, Schaffer D, Osawa E, Goga A, Ho D. PMID: 21389265.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    66. Imaging of blood flow using hyperpolarized [(13)C]urea in preclinical cancer models. J Magn Reson Imaging. 2011 Mar; 33(3):692-7. von Morze C, Larson PE, Hu S, Keshari K, Wilson DM, Ardenkjaer-Larsen JH, Goga A, Bok R, Kurhanewicz J, Vigneron DB. PMID: 21563254; PMCID: PMC3566235.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    67. miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nat Med. 2010 Oct; 16(10):1134-40. Swarbrick A, Woods SL, Shaw A, Balakrishnan A, Phua Y, Nguyen A, Chanthery Y, Lim L, Ashton LJ, Judson RL, Huskey N, Blelloch R, Haber M, Norris MD, Lengyel P, Hackett CS, Preiss T, Chetcuti A, Sullivan CS, Marcusson EG, Weiss W, L'Etoile N, Goga A. PMID: 20871609; PMCID: PMC3019350.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
    68. Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase. Proc Natl Acad Sci U S A. 2010 Aug 03; 107(31):13836-41. Yang D, Liu H, Goga A, Kim S, Yuneva M, Bishop JM. PMID: 20643922; PMCID: PMC2922232.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    69. Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state. Blood. 2010 Sep 02; 116(9):1498-505. den Hollander J, Rimpi S, Doherty JR, Rudelius M, Buck A, Hoellein A, Kremer M, Graf N, Scheerer M, Hall MA, Goga A, von Bubnoff N, Duyster J, Peschel C, Cleveland JL, Nilsson JA, Keller U. PMID: 20519624; PMCID: PMC2938839.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    70. Nuclear entry of a cGMP-dependent kinase converts transient into long-lasting olfactory adaptation. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):6016-21. Lee JI, O'Halloran DM, Eastham-Anderson J, Juang BT, Kaye JA, Scott Hamilton O, Lesch B, Goga A, L'Etoile ND. PMID: 20220099; PMCID: PMC2851914.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    71. 3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer. Magn Reson Med. 2010 Feb; 63(2):312-21. Hu S, Lustig M, Balakrishnan A, Larson PE, Bok R, Kurhanewicz J, Nelson SJ, Goga A, Pauly JM, Vigneron DB. PMID: 20017160; PMCID: PMC2829256.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimals
    72. Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. J Biol Chem. 2009 Jul 03; 284(27):18515-24. Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A, Horiuchi D, Lebbink RJ, Mo YY, Goga A, McManus MT. PMID: 19419954; PMCID: PMC2709372.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCells
    73. A 3'UTR pumilio-binding element directs translational activation in olfactory sensory neurons. Neuron. 2009 Jan 15; 61(1):57-70. Kaye JA, Rose NC, Goldsworthy B, Goga A, L'Etoile ND. PMID: 19146813; PMCID: PMC4274156.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    74. Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell. 2008 Dec 09; 14(6):471-84. Cairo S, Armengol C, De Reyniès A, Wei Y, Thomas E, Renard CA, Goga A, Balakrishnan A, Semeraro M, Gresh L, Pontoglio M, Strick-Marchand H, Levillayer F, Nouet Y, Rickman D, Gauthier F, Branchereau S, Brugières L, Laithier V, Bouvier R, Boman F, Basso G, Michiels JF, Hofman P, Arbez-Gindre F, Jouan H, Rousselet-Chapeau MC, Berrebi D, Marcellin L, Plenat F, Zachar D, Joubert M, Selves J, Pasquier D, Bioulac-Sage P, Grotzer M, Childs M, Fabre M, Buendia MA. PMID: 19061838.
      View in: PubMed   Mentions: 207     Fields:    Translation:HumansAnimalsCells
    75. Anti-oncomir suppression of tumor phenotypes. Mol Interv. 2007 Aug; 7(4):199-202, 180. Goga A, Benz C. PMID: 17827440.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    76. Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC. Nat Med. 2007 Jul; 13(7):820-7. Goga A, Yang D, Tward AD, Morgan DO, Bishop JM. PMID: 17589519.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimalsCells
    77. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J Biol Chem. 2007 Jan 12; 282(2):1479-86. Scott GK, Goga A, Bhaumik D, Berger CE, Sullivan CS, Benz CC. PMID: 17110380.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansCells
    78. RNA interference (RNAi) with RNase III-prepared siRNAs. Methods Mol Biol. 2004; 252:471-82. Yang D, Goga A, Bishop JM. PMID: 15017072.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    79. Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc Natl Acad Sci U S A. 2002 Jul 23; 99(15):9942-7. Yang D, Buchholz F, Huang Z, Goga A, Chen CY, Brodsky FM, Bishop JM. PMID: 12096193; PMCID: PMC126604.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
    80. A functional screen for regulators of the c-Abl protein tyrosine kinase. Leukemia. 1997 Apr; 11 Suppl 3:313-5. Moro M, Walkenhorst J, Goga A, Witte ON, Superti-Furga G. PMID: 9209375.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    81. Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia. Mol Cell Biol. 1996 Aug; 16(8):4107-16. Golub TR, Goga A, Barker GF, Afar DE, McLaughlin J, Bohlander SK, Rowley JD, Witte ON, Gilliland DG. PMID: 8754809; PMCID: PMC231407.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    82. Analysis of human c-Abl tyrosine kinase activity and regulation in S. pombe. Oncogene. 1996 Apr 04; 12(7):1513-20. Walkenhorst J, Goga A, Witte ON, Superti-Furga G. PMID: 8622867.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    83. Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene. Cell. 1995 Sep 22; 82(6):981-8. Goga A, McLaughlin J, Afar DE, Saffran DC, Witte ON. PMID: 7553858.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    84. p53 dependent growth suppression by the c-Abl nuclear tyrosine kinase. Oncogene. 1995 Aug 17; 11(4):791-9. Goga A, Liu X, Hambuch TM, Senechal K, Major E, Berk AJ, Witte ON, Sawyers CL. PMID: 7651743.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    85. Transcriptional activation of a ras-like gene (kir) by oncogenic tyrosine kinases. Proc Natl Acad Sci U S A. 1994 Dec 20; 91(26):12448-52. Cohen L, Mohr R, Chen YY, Huang M, Kato R, Dorin D, Tamanoi F, Goga A, Afar D, Rosenberg N, et al. PMID: 7809057; PMCID: PMC45455.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    86. Differential complementation of Bcr-Abl point mutants with c-Myc. Science. 1994 Apr 15; 264(5157):424-6. Afar DE, Goga A, McLaughlin J, Witte ON, Sawyers CL. PMID: 8153630.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    87. The nuclear tyrosine kinase c-Abl negatively regulates cell growth. Cell. 1994 Apr 08; 77(1):121-31. Sawyers CL, McLaughlin J, Goga A, Havlik M, Witte O. PMID: 7512450.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    88. Genetic approaches to defining signaling by the CML-associated tyrosine kinase BCR-ABL. Cold Spring Harb Symp Quant Biol. 1994; 59:589-94. Afar DE, Goga A, Cohen L, Sawyers CL, McLaughlin J, Mohr RN, Witte ON. PMID: 7587117.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    89. Oncogenic activation of c-ABL by mutation within its last exon. Mol Cell Biol. 1993 Aug; 13(8):4967-75. Goga A, McLaughlin J, Pendergast AM, Parmar K, Muller A, Rosenberg N, Witte ON. PMID: 8336729; PMCID: PMC360140.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
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