Sei Lee, MD, MAS

Title(s)Professor, Medicine
SchoolSchool of Medicine
Phone415-221-4810 ext. 24543
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoCert2005 Medicine (Advance Training in Clinical Research)
    Collapse Awards and Honors
    University of Illinois1997Alpha Omega Alpha
    University of Illinois1999King's College (London) Scholarship
    University of Illinois1999Commencement Speaker
    UCSF2008Hartford Foundation Outcomes Research Scholar
    UCSF2009J Gen Internal Med Distinguished Reviewer
    UCSF2010Hartford Foundation Center of Excellence Scholar
    UCSF2010Ann Internal Med Top Grade Reviewer
    National Institute on Aging and the American Federation of Aging Research2011Beeson Scholar in Aging Research
    American Geriatrics Society2012Merck/AGS New Investigator Award
    American Geriatrics Society2012Best Clinical-Decision Making Paper
    American Geriatrics Society2014Outstanding Committee Service Award

    Collapse Overview 
    Collapse Overview
    Sei Lee is an Professor in the Division of Geriatrics and Senior Scholar for the San Francisco VA Quality Scholars fellowship. His research focuses on improving the targeting of preventive interventions in older adults to maximize benefits and minimize harms. Dr. Lee attended medical school at the University of Illinois-Rockford, then moved to UCSF where he completed Primary Care Internal Medicine residency and a Geriatric Medicine fellowship. He also completed the VA Quality Scholars fellowship, receiving advanced training in methodologies related to healthcare quality from the San Francisco VA and obtained a Master’s degree in clinical research from UCSF.

    Dr. Lee joined the Division of Geriatrics faculty in 2007. Dr. Lee’s research examines how a patient’s health status can help individualize preventive and treatment decisions, with a special focus on diabetes care for frail nursing home residents. Dr. Lee is an expert in clinical prediction and has published research on predicting mortality, functional decline, dementia and pneumonia. In his clinical work, Dr. Lee supervises and trains residents, fellows and medical students while providing care for internal medicine and palliative care patients at the San Francisco Veterans Affairs Medical Center.

    When not at work, he's usually trying to entertain his 3 kids. He enjoys commuting on his scooter, hiking and mountain biking.

    Collapse Research 
    Collapse Research Activities and Funding
    Prognostic calculators for patients with Alzheimers disease and related dementias
    NIH/NIA R01AG057751Aug 15, 2018 - Apr 30, 2022
    Role: Principal Investigator
    Development and Validation of 10-Year Life Expectancy Calculators to Individualize Veterans? Prevention Decisions
    VA I01HX002135Feb 1, 2017 - Jan 31, 2021
    Role: Principal Investigator
    Developing prognostic models for life expectancy and geriatric outcomes
    NIH/NIA R01AG047897May 15, 2015 - Jan 31, 2019
    Role: Co-Principal Investigator
    Individualizing Treatment for Nursing Home Residents with Diabetes Mellitus
    NIH/NIA K23AG040779Sep 1, 2011 - Aug 31, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Faculty Mentoring
    Collapse Featured Presentations

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Kotwal AA, Walter LC, Lee SJ, Dale W. Are We Choosing Wisely? Older Adults' Cancer Screening Intentions and Recalled Discussions with Physicians About Stopping. J Gen Intern Med. 2019 May 30. PMID: 31147981.
      View in: PubMed
    2. David D, Dalton J, Magny-Normilus C, Brain MM, Linster T, Lee SJ. The Quality of Family Relationships, Diabetes Self-Care, and Health Outcomes in Older Adults. Diabetes Spectr. 2019 May; 32(2):132-138. PMID: 31168284.
      View in: PubMed
    3. Stephens CE, Halifax E, David D, Bui N, Lee SJ, Shim J, Ritchie CS. "They Don't Trust Us": The Influence of Perceptions of Inadequate Nursing Home Care on Emergency Department Transfers and the Potential Role for Telehealth. Clin Nurs Res. 2019 Apr 21; 1054773819835015. PMID: 31007055.
      View in: PubMed
    4. Dudley N, Ritchie CS, Stijacic-Cenzer I, Lee SJ. Palliative Care Needs in Oncology, Cardiology, and Neurology Clinic Patients in the USA. J Gen Intern Med. 2019 Feb 07. PMID: 30734190.
      View in: PubMed
    5. Lee SJ. Frailty and mortality: 'Same-same but Different'. BMJ Qual Saf. 2019 Apr; 28(4):263-265. PMID: 30606804.
      View in: PubMed
    6. Nicosia FM, Spar MJ, Steinman MA, Lee SJ, Brown RT. Making Function Part of the Conversation: Clinician Perspectives on Measuring Functional Status in Primary Care. J Am Geriatr Soc. 2019 Mar; 67(3):493-502. PMID: 30506667.
      View in: PubMed
    7. Dudley N, Lee SJ, Stijacic-Cenzer I, Ritchie CS. Prevalence of Multimorbidity Among Older Adults With Advanced Illness Visits to U.S. Subspecialty Clinics. J Pain Symptom Manage. 2018 Jul; 56(1):e4-e6. PMID: 29550359.
      View in: PubMed
    8. Lee SJ, Larson EB, Dublin S, Walker R, Marcum Z, Barnes D. A Cohort Study of Healthcare Utilization in Older Adults with Undiagnosed Dementia. J Gen Intern Med. 2018 01; 33(1):13-15. PMID: 28849435.
      View in: PubMed
    9. Stephens CE, Hunt LJ, Bui N, Halifax E, Ritchie CS, Lee SJ. Palliative Care Eligibility, Symptom Burden, and Quality-of-Life Ratings in Nursing Home Residents. JAMA Intern Med. 2018 01 01; 178(1):141-142. PMID: 29159368.
      View in: PubMed
    10. Lee SJ, Kim CM. Individualizing Prevention for Older Adults. J Am Geriatr Soc. 2018 Feb; 66(2):229-234. PMID: 29155445.
      View in: PubMed
    11. Brown RT, Diaz-Ramirez LG, Boscardin WJ, Lee SJ, Steinman MA. Functional Impairment and Decline in Middle Age: A Cohort Study. Ann Intern Med. 2017 Dec 05; 167(11):761-768. PMID: 29132150.
      View in: PubMed
    12. Lee SJ. Glycemic Control and Functionality in Nursing Homes-More Than HbA1c-Reply. JAMA Intern Med. 2017 06 01; 177(6):894. PMID: 28586810.
      View in: PubMed
    13. Steinman MA, Zullo AR, Lee Y, Daiello LA, Boscardin WJ, Dore DD, Gan S, Fung K, Lee SJ, Komaiko KD, Mor V. Association of ß-Blockers With Functional Outcomes, Death, and Rehospitalization in Older Nursing Home Residents After Acute Myocardial Infarction. JAMA Intern Med. 2017 02 01; 177(2):254-262. PMID: 27942713.
      View in: PubMed
    14. Romo RD, Lee SJ. Changes in Social Function as a Trigger to Screen for Cognitive Impairment. J Gen Intern Med. 2016 08; 31(8):826-7. PMID: 27245052.
      View in: PubMed
    15. Barnhart C, McClymont K, Smith AK, Au-Yeung A, Lee SJ. "Everyone else gets ice cream here more often than I do--It burns me up"--Perspectives on Diabetes Care from Nursing Home Residents and their Doctors. BMC Geriatr. 2016 Jan 26; 16:28. PMID: 26813788.
      View in: PubMed
    16. Romo RD, Lee SJ, Miao Y, Boscardin WJ, Smith AK. Subjective, Objective, and Observed Long-term Survival: A Longitudinal Cohort Study. JAMA Intern Med. 2015 Dec; 175(12):1986-8. PMID: 26502331; PMCID: PMC4699655.
    17. Stephens C, Halifax E, Bui N, Lee SJ, Harrington C, Shim J, Ritchie C. Provider Perspectives on the Influence of Family on Nursing Home Resident Transfers to the Emergency Department: Crises at the End of Life. Curr Gerontol Geriatr Res. 2015; 2015:893062. PMID: 26379704.
      View in: PubMed
    18. Lee SJ, Stijacic-Cenzer I, Barnhart C, McClymont K, Steinman MA. Changing Patterns of Glucose-Lowering Medication Use in VA Nursing Home Residents With Diabetes, 2005 to 2011. J Am Med Dir Assoc. 2015 Oct 01; 16(10):898.e9-14. PMID: 26272298.
      View in: PubMed
    19. Tang V, Boscardin WJ, Stijacic-Cenzer I, Lee SJ. Time to benefit for colorectal cancer screening: survival meta-analysis of flexible sigmoidoscopy trials. BMJ. 2015 Apr 16; 350:h1662. PMID: 25881903; PMCID: PMC4399600.
    20. Lee SJ, Jacobson MA, Johnston CB. Improving Diabetes Care for Hospice Patients. Am J Hosp Palliat Care. 2016 Jul; 33(6):517-9. PMID: 25852204.
      View in: PubMed
    21. Chodos AH, Lee SJ. Journalists, district attorneys and researchers: why IRBs should get in the middle. BMC Med Ethics. 2015 Mar 29; 16:19. PMID: 25889147; PMCID: PMC4392736.
    22. Hsu A, Nakagawa S, Walter LC, Van Den Eeden SK, Brown JS, Thom DH, Lee SJ, Huang AJ. The burden of nocturia among middle-aged and older women. Obstet Gynecol. 2015 Jan; 125(1):35-43. PMID: 25560101; PMCID: PMC4286307.
    23. Hsu A, Conell-Price J, Stijacic Cenzer I, Eng C, Huang AJ, Rice-Trumble K, Lee SJ. Predictors of urinary incontinence in community-dwelling frail older adults with diabetes mellitus in a cross-sectional study. BMC Geriatr. 2014 Dec 16; 14:137. PMID: 25514968; PMCID: PMC4274753.
    24. Lee SJ, Ritchie CS, Yaffe K, Stijacic Cenzer I, Barnes DE. A clinical index to predict progression from mild cognitive impairment to dementia due to Alzheimer's disease. PLoS One. 2014; 9(12):e113535. PMID: 25486250; PMCID: PMC4259326.
    25. McClymont KM, Lee SJ, Schonberg MA, Widera E, Miao Y, Smith AK. Usefulness and effect of online prognostic calculators. J Am Geriatr Soc. 2014 Dec; 62(12):2444-5. PMID: 25516045; PMCID: PMC4273751.
    26. Lee SJ, Boscardin WJ, Kirby KA, Covinsky KE. Individualizing life expectancy estimates for older adults using the Gompertz Law of Human Mortality. PLoS One. 2014; 9(9):e108540. PMID: 25265291; PMCID: PMC4180452.
    27. Lee SJ. So much insulin, so much hypoglycemia. JAMA Intern Med. 2014 May; 174(5):686-8. PMID: 24614940; PMCID: PMC4067162.
    28. Lee SJ, Leipzig RM, Walter LC. Lag time to benefit for preventive therapies--reply. JAMA. 2014 Apr 16; 311(15):1567-8. PMID: 24737375.
      View in: PubMed
    29. Stephens CE, Sackett N, Govindarajan P, Lee SJ. Emergency department visits and hospitalizations by tube-fed nursing home residents with varying degrees of cognitive impairment: a national study. BMC Geriatr. 2014 Mar 20; 14:35. PMID: 24650076; PMCID: PMC3994482.
    30. Barnes DE, Cenzer IS, Yaffe K, Ritchie CS, Lee SJ. A point-based tool to predict conversion from mild cognitive impairment to probable Alzheimer's disease. Alzheimers Dement. 2014 Nov; 10(6):646-55. PMID: 24495339.
      View in: PubMed
    31. Lee SJ, Leipzig RM, Walter LC. Incorporating lag time to benefit into prevention decisions for older adults. JAMA. 2013 Dec 25; 310(24):2609-10. PMID: 24322396; PMCID: PMC4049260.
    32. Lee SJ, Karter AJ, Thai JN, Van Den Eeden SK, Huang ES. Glycemic control and urinary incontinence in women with diabetes mellitus. J Womens Health (Larchmt). 2013 Dec; 22(12):1049-55. PMID: 24032999.
      View in: PubMed
    33. Stephens C, Sackett N, Pierce R, Schopfer D, Schmajuk G, Moy N, Bachhuber M, Wallhagen MI, Lee SJ. Transitional care challenges of rehospitalized veterans: listening to patients and providers. Popul Health Manag. 2013 Oct; 16(5):326-31. PMID: 23560514; PMCID: PMC3780306.
    34. Cruz M, Covinsky K, Widera EW, Stijacic-Cenzer I, Lee SJ. Predicting 10-year mortality for older adults. JAMA. 2013 Mar 06; 309(9):874-6. PMID: 23462780; PMCID: PMC3760279.
    35. Lee SJ, Boscardin WJ, Stijacic-Cenzer I, Conell-Price J, O'Brien S, Walter LC. Time lag to benefit after screening for breast and colorectal cancer: meta-analysis of survival data from the United States, Sweden, United Kingdom, and Denmark. BMJ. 2013 Jan 08; 346:e8441. PMID: 23299842; PMCID: PMC4688425.
    36. Steinman MA, Lee SJ, John Boscardin W, Miao Y, Fung KZ, Moore KL, Schwartz JB. Patterns of multimorbidity in elderly veterans. J Am Geriatr Soc. 2012 Oct; 60(10):1872-80. PMID: 23035702; PMCID: PMC4133992.
    37. Yau CK, Eng C, Cenzer IS, Boscardin WJ, Rice-Trumble K, Lee SJ. Glycosylated hemoglobin and functional decline in community-dwelling nursing home-eligible elderly adults with diabetes mellitus. J Am Geriatr Soc. 2012 Jul; 60(7):1215-21. PMID: 22702660; PMCID: PMC3566776.
    38. Steinman MA, Lee SJ, Peterson CA, Fung KZ, Goldstein MK. A clinically guided approach for improving performance measurement for hypertension. Med Care. 2012 May; 50(5):399-405. PMID: 22627680.
      View in: PubMed
    39. Yourman LC, Lee SJ, Schonberg MA, Widera EW, Smith AK. Prognostic indices for older adults: a systematic review. JAMA. 2012 Jan 11; 307(2):182-92. PMID: 22235089; PMCID: PMC3792853.
    40. Barnes DE, Lee SJ. Predicting Alzheimer's risk: why and how? Alzheimers Res Ther. 2011 Nov 25; 3(6):33. PMID: 22126363.
      View in: PubMed
    41. Lee SJ, Walter LC. Quality indicators for older adults: preventing unintended harms. JAMA. 2011 Oct 05; 306(13):1481-2. PMID: 21972311; PMCID: PMC3285267.
    42. Lee SJ, Boscardin WJ, Stijacic Cenzer I, Huang ES, Rice-Trumble K, Eng C. The risks and benefits of implementing glycemic control guidelines in frail older adults with diabetes mellitus. J Am Geriatr Soc. 2011 Apr; 59(4):666-72. PMID: 21480838.
      View in: PubMed
    43. Lee SJ, Eng C. Goals of glycemic control in frail older patients with diabetes. JAMA. 2011 Apr 06; 305(13):1350-1. PMID: 21467289; PMCID: PMC3773561.
    44. Lee SJ, Steinman MA, Tan EJ. Volunteering, driving status, and mortality in U.S. retirees. J Am Geriatr Soc. 2011 Feb; 59(2):274-80. PMID: 21314648.
      View in: PubMed
    45. Williams BA, McGuire J, Lindsay RG, Baillargeon J, Cenzer IS, Lee SJ, Kushel M. Coming home: health status and homelessness risk of older pre-release prisoners. J Gen Intern Med. 2010 Oct; 25(10):1038-44. PMID: 20532651; PMCID: PMC2955468.
    46. Jennings LA, Auerbach AD, Maselli J, Pekow PS, Lindenauer PK, Lee SJ. Missed opportunities for osteoporosis treatment in patients hospitalized for hip fracture. J Am Geriatr Soc. 2010 Apr; 58(4):650-7. PMID: 20398147.
      View in: PubMed
    47. Splaine ME, Ogrinc G, Gilman SC, Aron DC, Estrada CA, Rosenthal GE, Lee S, Dittus RS, Batalden PB. The Department of Veterans Affairs National Quality Scholars Fellowship Program: experience from 10 years of training quality scholars. Acad Med. 2009 Dec; 84(12):1741-8. PMID: 19940583; PMCID: PMC3800745.
    48. Walter LC, Lindquist K, Nugent S, Schult T, Lee SJ, Casadei MA, Partin MR. Impact of age and comorbidity on colorectal cancer screening among older veterans. Ann Intern Med. 2009 Apr 07; 150(7):465-73. PMID: 19349631; PMCID: PMC3769097.
    49. Kernisan LP, Lee SJ, Boscardin WJ, Landefeld CS, Dudley RA. Association between hospital-reported Leapfrog Safe Practices Scores and inpatient mortality. JAMA. 2009 Apr 01; 301(13):1341-8. PMID: 19336709; PMCID: PMC2851624.
    50. Lee SJ, Sudore RL, Williams BA, Lindquist K, Chen HL, Covinsky KE. Functional limitations, socioeconomic status, and all-cause mortality in moderate alcohol drinkers. J Am Geriatr Soc. 2009 Jun; 57(6):955-62. PMID: 19473456; PMCID: PMC2847409.
    51. Lee SJ, Go AS, Lindquist K, Bertenthal D, Covinsky KE. Chronic conditions and mortality among the oldest old. Am J Public Health. 2008 Jul; 98(7):1209-14. PMID: 18511714; PMCID: PMC2424085.
    52. Lee SJ, Moody-Ayers SY, Landefeld CS, Walter LC, Lindquist K, Segal MR, Covinsky KE. The relationship between self-rated health and mortality in older black and white Americans. J Am Geriatr Soc. 2007 Oct; 55(10):1624-9. PMID: 17697102.
      View in: PubMed
    53. Lee SJ, Lindquist K, Segal MR, Covinsky KE. Development and validation of a prognostic index for 4-year mortality in older adults. JAMA. 2006 Feb 15; 295(7):801-8. PMID: 16478903.
      View in: PubMed