Mehrdad Matloubian, MD, PhD
|
Title(s) | Professor, Medicine |
---|
School | School of Medicine |
---|
Address | 533 Parnassus Avenue San Francisco CA 94117
|
---|
Phone | 415-476-0738 |
---|
vCard | Download vCard |
---|
|
|
Biography University of California, San Francisco | Postdoctoral Studies | | Graduate Division |
Overview I have a general interest in mechanisms of immune mediated diseases and approaches for a better understanding of the molecular bases of such processes. The goal is to provided therapeutic for treatment of autoimmune and inflammatory diseases through a better understanding of the involved pathways.
Research ORNG Applications Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.)
Click a Field or Translation tag to filter the publications.
-
A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands. Sci Signal. 2021 Feb 02; 14(668).
Shen L, Matloubian M, Kadlecek TA, Weiss A. PMID: 33531381.
View in: PubMed Mentions: Fields:
-
A phase Ib trial of the cyclin-dependent kinase inhibitor dinaciclib (dina) in combination with pembrolizumab (P) in patients with advanced triple-negative breast cancer (TNBC) and response correlation with MYC-overexpression. Journal of Clinical Oncology. 2020 May 20; 38(15_suppl):1076-1076.
Amy Jo Chien, Amelia S Gliwa, Siti Rahmaputri, Heidi F Dittrich, Melanie Catherine Majure, Hope S. Rugo, Michelle E. Melisko, Pamela N. Munster, John W. Park, Mark M. Moasser, Mehrdad Matloubian, Tasha Lea, Julia Rohrberg, Gregor Krings, Andrei Goga. .
View in: Publisher Site Mentions:
-
The Molecular Medicine Investigation Unit: Linking Patient Care and Scientific Inquiry in Physician-Scientist Training. J Grad Med Educ. 2020 Feb; 12(1):92-97.
Berger A, Matloubian M, Shah NP, Wachter RM, DeRisi JL, Anderson M. PMID: 32089799.
View in: PubMed Mentions: Fields: Translation: Humans
-
miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival. Cell Rep. 2019 08 20; 28(8):2169-2181.e4.
Gagnon JD, Kageyama R, Shehata HM, Fassett MS, Mar DJ, Wigton EJ, Johansson K, Litterman AJ, Odorizzi P, Simeonov D, Laidlaw BJ, Panduro M, Patel S, Jeker LT, Feeney ME, McManus MT, Marson A, Matloubian M, Sanjabi S, Ansel KM. PMID: 31433990.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
-
Perivascular Fibroblasts of the Developing Spleen Act as LTa1ß2-Dependent Precursors of Both T and B Zone Organizer Cells. Cell Rep. 2017 Nov 28; 21(9):2500-2514.
Schaeuble K, Britschgi MR, Scarpellino L, Favre S, Xu Y, Koroleva E, Lissandrin TKA, Link A, Matloubian M, Ware CF, Nedospasov SA, Tumanov AV, Cyster JG, Luther SA. PMID: 29186687.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
-
Sex- and corticotropin-releasing factor receptor 2- dependent actions of urocortin 1 during inflammation. . 2016 06 01; 310(11):R1244-57.
PMID: 27053649.
View in: PubMed Mentions:
-
522 Sex-Specific Responses of the Corticotropin-Releasing Factor System in a Mouse Model of Inflammatory Bowel Disease. Gastroenterology. 2015 Apr 1; 148(4):s-103.
Burcu Hasdemir, Shilpi Mahajan, Mehrdad Matloubian, Aditi Bhargava. .
View in: Publisher Site Mentions:
-
Cutting edge: An in vivo reporter reveals active B cell receptor signaling in the germinal center. J Immunol. 2015 Apr 01; 194(7):2993-7.
PMID: 25725108.
View in: PubMed Mentions: 19 Fields: Translation: AnimalsCells
-
A sharp T-cell antigen receptor signaling threshold for T-cell proliferation. Proc Natl Acad Sci U S A. 2014 Sep 02; 111(35):E3679-88.
PMID: 25136127.
View in: PubMed Mentions: 45 Fields: Translation: AnimalsCells
-
91 Homotypic T–T synapses promote collective CD8+ T cell differentiation through exchange of IFN gamma. Cytokine. 2013 Sep 1; 63(3):264.
Audrey Gérard, Omar Khan, Peter Beemiller, Erin Oswald, Joyce Hu, Mehrdad Matloubian, Matthew F. Krummel. .
View in: Publisher Site Mentions:
-
16 MIR-17~92 promotes T follicular helper cell differentiation and represses subset-inappropriate gene expression. Cytokine. 2013 Sep 1; 63(3):246-247.
Dirk Baumjohann, Robin Kageyama, Jonathan M. Clingan, Malika M. Morar, Sana Patel, Dimitri de Kouchkovsky, Oliver Bannard, Jeffrey A. Bluestone, Mehrdad Matloubian, K Mark Ansel, Lukas T. Jeker. .
View in: Publisher Site Mentions:
-
The microRNA cluster miR-17~92 promotes TFH cell differentiation and represses subset-inappropriate gene expression. Nat Immunol. 2013 Aug; 14(8):840-8.
PMID: 23812098.
View in: PubMed Mentions: 83 Fields: Translation: AnimalsCells
-
B Cell-intrinsic TLR7 signaling is required for optimal B cell responses during chronic viral infection. J Immunol. 2013 Jul 15; 191(2):810-8.
PMID: 23761632.
View in: PubMed Mentions: 25 Fields: Translation: AnimalsCells
-
IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. Int Immunol. 2013 Aug; 25(8):471-83.
PMID: 23657000.
View in: PubMed Mentions: 24 Fields: Translation: AnimalsCells
-
MicroRNA function in NK-cell biology. Immunol Rev. 2013 May; 253(1):40-52.
PMID: 23550637.
View in: PubMed Mentions: 31 Fields: Translation: HumansAnimalsCells
-
Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells. Nat Immunol. 2013 Apr; 14(4):356-63.
PMID: 23475183.
View in: PubMed Mentions: 50 Fields: Translation: AnimalsCells
-
Th1 cell induction in lymph nodes according to a red-blue chemokine map. Immunity. 2012 Dec 14; 37(6):954-6.
PMID: 23244716.
View in: PubMed Mentions: 7 Fields:
-
Differential roles for RIG-I-like receptors and nucleic acid-sensing TLR pathways in controlling a chronic viral infection. J Immunol. 2012 May 01; 188(9):4432-40.
PMID: 22447976.
View in: PubMed Mentions: 14 Fields: Translation: AnimalsCells
-
MicroRNA-29 regulates T-box transcription factors and interferon-? production in helper T cells. Immunity. 2011 Aug 26; 35(2):169-81.
PMID: 21820330.
View in: PubMed Mentions: 122 Fields: Translation: AnimalsCells
-
Expression of chemokine receptor CXCR3 on T cells affects the balance between effector and memory CD8 T-cell generation. Proc Natl Acad Sci U S A. 2011 May 24; 108(21):E118-27.
PMID: 21518913.
View in: PubMed Mentions: 55 Fields: Translation: AnimalsCells
-
Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16234-9.
Beinke S, Phee H, Clingan JM, Schlessinger J, Matloubian M, Weiss A. PMID: 20805505.
View in: PubMed Mentions: 22 Fields: Translation: AnimalsCells
-
S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress. Immunity. 2008 Jan; 28(1):122-33.
Pham TH, Okada T, Matloubian M, Lo CG, Cyster JG. PMID: 18164221.
View in: PubMed Mentions: 156 Fields: Translation: AnimalsCells
-
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proc Natl Acad Sci U S A. 2007 Sep 25; 104(39):15430-5.
Mueller SN, Matloubian M, Clemens DM, Sharpe AH, Freeman GJ, Gangappa S, Larsen CP, Ahmed R. PMID: 17878315.
View in: PubMed Mentions: 98 Fields: Translation: AnimalsCells
-
Regulation of homeostatic chemokine expression and cell trafficking during immune responses. Science. 2007 Aug 03; 317(5838):670-4.
Mueller SN, Hosiawa-Meagher KA, Konieczny BT, Sullivan BM, Bachmann MF, Locksley RM, Ahmed R, Matloubian M. PMID: 17673664.
View in: PubMed Mentions: 108 Fields: Translation: AnimalsCells
-
CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature. 2006 Mar 23; 440(7083):540-4.
Shiow LR, Rosen DB, Brdicková N, Xu Y, An J, Lanier LL, Cyster JG, Matloubian M. PMID: 16525420.
View in: PubMed Mentions: 422 Fields: Translation: HumansAnimalsCells
-
Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science. 2005 Sep 09; 309(5741):1735-9.
Schwab SR, Pereira JP, Matloubian M, Xu Y, Huang Y, Cyster JG. PMID: 16151014.
View in: PubMed Mentions: 307 Fields: Translation: AnimalsCells
-
Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone. Nat Immunol. 2004 Jul; 5(7):713-20.
Cinamon G, Matloubian M, Lesneski MJ, Xu Y, Low C, Lu T, Proia RL, Cyster JG. PMID: 15184895.
View in: PubMed Mentions: 129 Fields: Translation: AnimalsCells
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature. 2004 Jan 22; 427(6972):355-60.
Matloubian M, Lo CG, Cinamon G, Lesneski MJ, Xu Y, Brinkmann V, Allende ML, Proia RL, Cyster JG. PMID: 14737169.
View in: PubMed Mentions: 795 Fields: Translation: AnimalsCells
-
Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J Immunol. 2002 Jul 01; 169(1):424-33.
Luther SA, Bidgol A, Hargreaves DC, Schmidt A, Xu Y, Paniyadi J, Matloubian M, Cyster JG. PMID: 12077273.
View in: PubMed Mentions: 147 Fields: Translation: AnimalsCells
-
Distinct CD8 T cell functions mediate susceptibility to histoplasmosis during chronic viral infection. J Immunol. 2001 Oct 15; 167(8):4566-73.
Wu-Hsieh BA, Whitmire JK, de Fries R, Lin JS, Matloubian M, Ahmed R. PMID: 11591785.
View in: PubMed Mentions: 7 Fields: Translation: AnimalsCells
-
A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat Immunol. 2000 Oct; 1(4):298-304.
Matloubian M, David A, Engel S, Ryan JE, Cyster JG. PMID: 11017100.
View in: PubMed Mentions: 170 Fields: Translation: HumansAnimalsCells
-
A role for perforin in downregulating T-cell responses during chronic viral infection. J Virol. 1999 Mar; 73(3):2527-36.
Matloubian M, Suresh M, Glass A, Galvan M, Chow K, Whitmire JK, Walsh CM, Clark WR, Ahmed R. PMID: 9971838.
View in: PubMed Mentions: 56 Fields: Translation: AnimalsCells
-
Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection. J Immunol. 1996 Dec 15; 157(12):5543-54.
van der Most RG, Sette A, Oseroff C, Alexander J, Murali-Krishna K, Lau LL, Southwood S, Sidney J, Chesnut RW, Matloubian M, Ahmed R. PMID: 8955205.
View in: PubMed Mentions: 66 Fields: Translation: AnimalsCells
-
Antiviral cytotoxic T-cell memory by vaccination with recombinant Listeria monocytogenes. J Virol. 1996 May; 70(5):2902-10.
Slifka MK, Shen H, Matloubian M, Jensen ER, Miller JF, Ahmed R. PMID: 8627765.
View in: PubMed Mentions: 15 Fields: Translation: AnimalsCells
-
Mechanisms of CTL-mediated cytoxicity. Seminars in Virology. 1996 Apr 1; 7(2):113-116.
William R. Clark, Craig M. Walsh, Mehrdad Matloubian, Alison A. Glass, Fumitaka Hayashi. .
View in: Publisher Site Mentions:
-
Molecular pathways of CTL-mediated cytotoxicity. Immunol Rev. 1995 Aug; 146:33-44.
Clark WR, Walsh CM, Glass AA, Hayashi F, Matloubian M, Ahmed R. PMID: 7493758.
View in: PubMed Mentions: 12 Fields: Translation: AnimalsCells
-
Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity. Proc Natl Acad Sci U S A. 1995 Apr 25; 92(9):3987-91.
Shen H, Slifka MK, Matloubian M, Jensen ER, Ahmed R, Miller JF. PMID: 7732018.
View in: PubMed Mentions: 92 Fields: Translation: AnimalsCells
-
Bone marrow is a major site of long-term antibody production after acute viral infection. J Virol. 1995 Mar; 69(3):1895-902.
Slifka MK, Matloubian M, Ahmed R. PMID: 7853531.
View in: PubMed Mentions: 126 Fields: Translation: AnimalsCells
-
Cell-mediated cytotoxicity in perforin-less mice. Int Rev Immunol. 1995; 13(1):1-14.
Clark WR, Walsh CM, Glass AA, Huang MT, Ahmed R, Matloubian M. PMID: 7494105.
View in: PubMed Mentions: 7 Fields: Translation: AnimalsCells
-
CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection. J Virol. 1994 Dec; 68(12):8056-63.
Matloubian M, Concepcion RJ, Ahmed R. PMID: 7966595.
View in: PubMed Mentions: 413 Fields: Translation: AnimalsCells
-
Immune function in mice lacking the perforin gene. Proc Natl Acad Sci U S A. 1994 Nov 08; 91(23):10854-8.
Walsh CM, Matloubian M, Liu CC, Ueda R, Kurahara CG, Christensen JL, Huang MT, Young JD, Ahmed R, Clark WR. PMID: 7526382.
View in: PubMed Mentions: 150 Fields: Translation: AnimalsCells
-
Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus. J Virol. 1993 Dec; 67(12):7340-9.
Matloubian M, Kolhekar SR, Somasundaram T, Ahmed R. PMID: 7693969.
View in: PubMed Mentions: 96 Fields: Translation: AnimalsCells
-
Molecular basis of organ-specific selection of viral variants during chronic infection. J Virol. 1991 Aug; 65(8):4242-7.
Ahmed R, Hahn CS, Somasundaram T, Villarete L, Matloubian M, Strauss JH. PMID: 2072451.
View in: PubMed Mentions: 40 Fields: Translation: AnimalsCells
-
Genetic basis of viral persistence: single amino acid change in the viral glycoprotein affects ability of lymphocytic choriomeningitis virus to persist in adult mice. J Exp Med. 1990 Oct 01; 172(4):1043-8.
Matloubian M, Somasundaram T, Kolhekar SR, Selvakumar R, Ahmed R. PMID: 2212940.
View in: PubMed Mentions: 59 Fields: Translation: AnimalsCells
-
Genetic analysis of in vivo-selected viral variants causing chronic infection: importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus. J Virol. 1988 Sep; 62(9):3301-8.
Ahmed R, Simon RS, Matloubian M, Kolhekar SR, Southern PJ, Freedman DM. PMID: 3261347.
View in: PubMed Mentions: 27 Fields: Translation: AnimalsCells
This graph shows the total number of publications by year. To see the data as text, click here.
This graph shows the total number of publications by year. To return to the graph, click here.
Year | Publications |
---|
1991 | 1 | 1993 | 1 | 1994 | 2 | 1995 | 4 | 1996 | 3 | 1999 | 1 | 2000 | 1 | 2001 | 1 | 2002 | 1 | 2004 | 2 | 2005 | 1 | 2006 | 1 | 2007 | 3 | 2010 | 1 | 2011 | 2 | 2012 | 2 | 2013 | 7 | 2014 | 1 | 2015 | 2 | 2016 | 1 | 2017 | 1 | 2019 | 1 | 2020 | 2 | 2021 | 1 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
newest
oldest
line numbers
double spacing
all authors
publication IDs
|
Derived automatically from this person's publications.
_
People in Profiles who have published with this person.
_
People who share similar concepts with this person.
_
Search Department
_
|