Aaron Fields, PhD

Title(s)Associate Professor, Orthopaedic Surgery
SchoolSchool of Medicine
Address513 Parnassus Avenue, MSB, #1159
San Francisco CA 94143
Phone415-476-0960
ORCID ORCID Icon0000-0001-6460-4506 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of DenverBS2005Mechanical Engineering
    University of California, BerkeleyPhD2010Mechanical Engineering
    University of California, San FranciscoPostdoctoral Fellowship2013Orthopaedic Surgery
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    U.S. Bone and Joint Initiative2015Young Investigator Initiative
    Orthopaedic Research Society2017Spine Section Podium Award
    North American Spine Society2018Young Investigator Research Grant Award
    International Society for the Study of the Lumbar Spine2019Best Basic Science Poster Award
    International Society for the Study of the Lumbar Spine2023ISSLS Prize in Bioengineering Science

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    UCSF Musculoskeletal Training Program
    NIH T32AR080618Apr 1, 2023 - Mar 31, 2028
    Role: Program Director
    Role of the gut microbiome in the progression of vertebral endplate bone marrow lesions (Modic changes) in chronic low back pain
    UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain May 1, 2021 - Apr 30, 2022
    Role: Principal Investigator
    Enhancing cartilage endplate permeability to improve disc nutrition
    UCSF School of Medicine Jul 1, 2020 - Jun 30, 2021
    Role: Principal Investigator
    Novel imaging of endplate biomarkers in chronic low back pain
    NIH UH3AR076719Sep 26, 2019 - Aug 31, 2024
    Role: Principal Investigator
    Novel imaging of endplate biomarkers in chronic low back pain
    NIH UH2AR076719Sep 26, 2019 - Aug 31, 2021
    Role: Principal Investigator
    UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain
    NIH U19AR076737Sep 25, 2019 - May 31, 2024
    Role: Co-Investigator
    Core Center for Musculoskeletal Biology and Medicine
    NIH P30AR075055Jul 1, 2019 - Jun 30, 2024
    Role: Co-Investigator
    Does enhancing cartilage endplate permeability improve nucleus pulposus cell function?
    North American Spine Society Jan 1, 2019 - Dec 31, 2019
    Role: Principal Investigator
    Role of the cartilage endplate in spinal disc degeneration
    NIH R01AR070198Apr 1, 2017 - Jan 31, 2022
    Role: Principal Investigator
    Does Cartilage Endplate Permeability Impact Nucleus Pulposus Cell Function?
    North American Spine Society Jan 1, 2017 - Dec 31, 2017
    Role: Principal Investigator
    Measurement of the effect of cartilage endplate permeability on disc cell function using in situ hybridization
    UCSF Core Center for Musculoskeletal Biology in Medicine Jun 1, 2016 - May 31, 2017
    Role: Principal Investigator
    Enhancing endplate permeability to treat or prevent intervertebral disc degeneration
    UCSF Center for Disruptive Musculoskeletal Innovation Oct 1, 2015 - Sep 30, 2016
    Role: Principal Investigator
    Cartilage endplate composition and disc degeneration: investigating nutrient diffusion and disc cell viability
    UCSF School of Medicine Jul 1, 2015 - Jun 30, 2016
    Role: Principal Investigator
    Endplate dysfunction and disc degeneration: investigating solute transport, disc cell viability and new imaging methods
    UCSF Core Center for Musculoskeletal Biology in Medicine Apr 3, 2015 - Jun 30, 2016
    Role: Principal Investigator
    Phenotypes of pathologic vertebral endplate degeneration
    NIH R56AR063705Aug 1, 2013 - Aug 31, 2020
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. [Evidence-based interventions to treat chronic low back pain: treatment selection for a personalized medicine approach : German version]. Schmerz. 2024 Feb 21. Mauck MC, Aylward AF, Barton CE, Birckhead B, Carey T, Dalton DM, Fields AJ, Fritz J, Hassett AL, Hoffmeyer A, Jones SB, McLean SA, Mehling WE, O'Neill CW, Schneider MJ, Williams DA, Zheng P, Wasan AD. PMID: 38381187.
      View in: PubMed   Mentions:    Fields:    
    2. Low back pain patients with Modic type 1 changes exhibit distinct bacterial and non-bacterial subtypes. Osteoarthr Cartil Open. 2024 Mar; 6(1):100434. Heggli I, Mengis T, Laux CJ, Opitz L, Herger N, Menghini D, Schuepbach R, Farshad-Amacker NA, Brunner F, Fields AJ, Farshad M, Distler O, Dudli S. PMID: 38322145; PMCID: PMC10844677.
      View in: PubMed   Mentions:
    3. Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the University of California Davis type 2 diabetes mellitus (UCD-T2DM) rat model. PNAS Nexus. 2023 Dec; 2(12):pgad363. Rosenberg JL, Schaible E, Bostrom A, Lazar AA, Graham JL, Stanhope KL, Ritchie RO, Alliston TN, Lotz JC, Havel PJ, Acevedo C, Fields AJ. PMID: 38094616; PMCID: PMC10718642.
      View in: PubMed   Mentions:
    4. Non-enzymatic glycation reduces glucose transport in the human cartilage endplate independently of matrix porosity or proteoglycan content. JOR Spine. 2024 Mar; 7(1):e1297. Jung JY, Habib M, Morrissette LJ, Timmons SC, Maerz T, Fields AJ. PMID: 38222801; PMCID: PMC10782066.
      View in: PubMed   Mentions:
    5. Magnetic Resonance Imaging of the Lumbar Spine: Recommendations for Acquisition and Image Evaluation from the BACPAC Spine Imaging Working Group. Pain Med. 2023 08 04; 24(Suppl 1):S81-S94. Sollmann N, Fields AJ, O'Neill C, Nardo L, Majumdar S, Chin CT, Tosun D, Han M, Vu AT, Ozhinsky E, Shah LM, Harris RE, Lobo R, Anderst W, Herzog R, Psioda MA, Standaert CJ, Price RT, Lotz JC, Link TM, Krug R. PMID: 36069660; PMCID: PMC10403314.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Protocol for Biospecimen Collection and Analysis Within the BACPAC Research Program. Pain Med. 2023 08 04; 24(Suppl 1):S71-S80. Fields AJ, Dudli S, Schrepf A, Kim A, Pham B, Gallego E, Mendoza S, Meropol SB, Darwin J, Sowa G, Vo NV. PMID: 36525387; PMCID: PMC10403310.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods. Pain Med. 2023 08 04; 24(Suppl 1):S3-S12. Mauck MC, Lotz J, Psioda MA, Carey TS, Clauw DJ, Majumdar S, Marras WS, Vo N, Aylward A, Hoffmeyer A, Zheng P, Ivanova A, McCumber M, Carson C, Anstrom KJ, Bowden AE, Dalton D, Derr L, Dufour J, Fields AJ, Fritz J, Hassett AL, Harte SE, Hue TF, Krug R, Loggia ML, Mageswaran P, McLean SA, Mitchell UH, O'Neill C, Pedoia V, Quirk DA, Rhon DI, Rieke V, Shah L, Sowa G, Spiegel B, Wasan AD, Wey HM, LaVange L. PMID: 36622041; PMCID: PMC10403298.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. The Back Pain Consortium (BACPAC) Research Program Data Harmonization: Rationale for Data Elements and Standards. Pain Med. 2023 08 04; 24(Suppl 1):S95-S104. Batorsky A, Bowden AE, Darwin J, Fields AJ, Greco CM, Harris RE, Hue TF, Kakyomya J, Mehling W, O'Neill C, Patterson CG, Piva SR, Sollmann N, Toups V, Wasan AD, Wasserman R, Williams DA, Vo NV, Psioda MA, McCumber M. PMID: 36721327.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Bullying, harassment, and discrimination of musculoskeletal researchers and the impact of the COVID-19 pandemic: an international study. Eur Spine J. 2023 06; 32(6):1861-1875. Martin JT, Asimakopoulos D, Hornung AL, Toro SJ, Le Maitre CL, Chahine NO, Fields AJ, Gawri R, Giers MB, Smith LJ, Tang SY, Zehra U, Haglund L, Samartzis D. PMID: 37014436; PMCID: PMC10071222.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    10. Deep-learning-based biomarker of spinal cartilage endplate health using ultra-short echo time magnetic resonance imaging. Quant Imaging Med Surg. 2023 May 01; 13(5):2807-2821. Bonnheim NB, Wang L, Lazar AA, Chachad R, Zhou J, Guo X, O'Neill C, Castellanos J, Du J, Jang H, Krug R, Fields AJ. PMID: 37179932; PMCID: PMC10167428.
      View in: PubMed   Mentions: 4  
    11. Intradiscal treatment of the cartilage endplate for improving solute transport and disc nutrition. Front Bioeng Biotechnol. 2023; 11:1111356. Habib M, Hussien S, Jeon O, Lotz JC, Wu PI, Alsberg E, Fields AJ. PMID: 36923455; PMCID: PMC10008947.
      View in: PubMed   Mentions: 3  
    12. ISSLS Prize in Bioengineering Science 2023: Age- and sex-related differences in lumbar intervertebral disc degeneration between patients with chronic low back pain and asymptomatic controls. Eur Spine J. 2023 05; 32(5):1517-1524. Bonnheim NB, Lazar AA, Kumar A, Akkaya Z, Zhou J, Guo X, O'Neill C, Link TM, Lotz JC, Krug R, Fields AJ. PMID: 36805320; PMCID: PMC10205694.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. UTE-MRI for Spinal Applications. MRI of Short and Ultrashort-T_2 Tissues. 2023 Jan 1; 441-450. Bonnheim BN, Han HM, Fields FA, Chin CC, Krug KR. .
      View in: Publisher Site   Mentions:
    14. Evidence-based interventions to treat chronic low back pain: treatment selection for a personalized medicine approach. Pain Rep. 2022 Sep-Oct; 7(5):e1019. Mauck MC, Aylward AF, Barton CE, Birckhead B, Carey T, Dalton DM, Fields AJ, Fritz J, Hassett AL, Hoffmeyer A, Jones SB, McLean SA, Mehling WE, O'Neill CW, Schneider MJ, Williams DA, Zheng P, Wasan AD. PMID: 36203645; PMCID: PMC9529058.
      View in: PubMed   Mentions: 5  
    15. Influence of patient-specific factors when comparing multifidus fat infiltration between chronic low back pain patients and asymptomatic controls. JOR Spine. 2022 Dec; 5(4):e1217. Ballatori AM, Shahrestani S, Nyayapati P, Agarwal V, Krug R, Han M, Fields AJ, O'Neill C, Demir-Deviren S, Lotz JC, Bailey JF. PMID: 36601370; PMCID: PMC9799081.
      View in: PubMed   Mentions: 1  
    16. Spatial distribution of fat infiltration within the paraspinal muscles: implications for chronic low back pain. Eur Spine J. 2022 11; 31(11):2875-2883. Khattab K, Dziesinski LK, Crawford R, Ballatori A, Nyayapati P, Krug R, Fields A, O'Neill CW, Lotz JC, Bailey JF. PMID: 35776179; PMCID: PMC9637053.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. The contributions of cartilage endplate composition and vertebral bone marrow fat to intervertebral disc degeneration in patients with chronic low back pain. Eur Spine J. 2022 07; 31(7):1866-1872. Bonnheim NB, Wang L, Lazar AA, Zhou J, Chachad R, Sollmann N, Guo X, Iriondo C, O'Neill C, Lotz JC, Link TM, Krug R, Fields AJ. PMID: 35441890; PMCID: PMC9252939.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    18. Using hierarchical unsupervised learning to integrate and reduce multi-level and multi-paraspinal muscle MRI data in relation to low back pain. Eur Spine J. 2022 08; 31(8):2046-2056. Torres-Espin A, Keller A, Johnson GTA, Fields AJ, Krug R, Ferguson AR, Hargens AR, O'Neill CW, Lotz JC, Bailey JF. PMID: 35333958; PMCID: PMC9338899.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Paraspinal Muscle in Chronic Low Back Pain: Comparison Between Standard Parameters and Chemical Shift Encoding-Based Water-Fat MRI. J Magn Reson Imaging. 2022 11; 56(5):1600-1608. Sollmann N, Bonnheim NB, Joseph GB, Chachad R, Zhou J, Akkaya Z, Pirmoazen AM, Bailey JF, Guo X, Lazar AA, Link TM, Fields AJ, Krug R. PMID: 35285561; PMCID: PMC9470775.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    20. Non-enzymatic glycation of annulus fibrosus alters tissue-level failure mechanics in tension. J Mech Behav Biomed Mater. 2022 02; 126:104992. Werbner B, Lee M, Lee A, Yang L, Habib M, Fields AJ, O'Connell GD. PMID: 34864399.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    21. Development of a standardized histopathology scoring system for human intervertebral disc degeneration: an Orthopaedic Research Society Spine Section Initiative. JOR Spine. 2021 Jun; 4(2):e1167. Le Maitre CL, Dahia CL, Giers M, Illien-Junger S, Cicione C, Samartzis D, Vadala G, Fields A, Lotz J. PMID: 34337340; PMCID: PMC8313169.
      View in: PubMed   Mentions: 17  
    22. Measurement of vertebral endplate bone marrow lesion (Modic change) composition with water-fat MRI and relationship to patient-reported outcome measures. Eur Spine J. 2021 09; 30(9):2549-2556. Fields AJ, Ballatori A, Han M, Bailey JF, McCormick ZL, O'Neill CW, Demir-Deviren S, Krug R, Lotz JC. PMID: 33547944; PMCID: PMC8697722.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Automatic Vertebral Body Segmentation Based on Deep Learning of Dixon Images for Bone Marrow Fat Fraction Quantification. Front Endocrinol (Lausanne). 2020; 11:612. Zhou J, Damasceno PF, Chachad R, Cheung JR, Ballatori A, Lotz JC, Lazar AA, Link TM, Fields AJ, Krug R. PMID: 32982989; PMCID: PMC7492292.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    24. Evaluation of human cartilage endplate composition using MRI: Spatial variation, association with adjacent disc degeneration, and in vivo repeatability. J Orthop Res. 2021 07; 39(7):1470-1478. Wang L, Han M, Wong J, Zheng P, Lazar AA, Krug R, Fields AJ. PMID: 32592504; PMCID: PMC7765737.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    25. Serum Biomarkers for Connective Tissue and Basement Membrane Remodeling are Associated with Vertebral Endplate Bone Marrow Lesions as Seen on MRI (Modic Changes). Int J Mol Sci. 2020 May 27; 21(11). Dudli S, Ballatori A, Bay-Jensen AC, McCormick ZL, O'Neill CW, Demir-Deviren S, Krug R, Heggli I, Juengel A, Karppinen J, Brunner F, Farshad M, Distler O, Lotz JC, Fields AJ. PMID: 32471173; PMCID: PMC7312719.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    26. Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis. Bone Res. 2019; 7:34. Mazur CM, Woo JJ, Yee CS, Fields AJ, Acevedo C, Bailey KN, Kaya S, Fowler TW, Lotz JC, Dang A, Kuo AC, Vail TP, Alliston T. PMID: 31700695; PMCID: PMC6828661.
      View in: PubMed   Mentions: 41  
    27. Measuring and reporting of vertebral endplate bone marrow lesions as seen on MRI (Modic changes): recommendations from the ISSLS Degenerative Spinal Phenotypes Group. Eur Spine J. 2019 10; 28(10):2266-2274. Fields AJ, Battié MC, Herzog RJ, Jarvik JG, Krug R, Link TM, Lotz JC, O'Neill CW, Sharma A, ISSLS Degenerative Spinal Phenotypes Group. PMID: 31446492; PMCID: PMC7205555.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    28. The Relationship Between Endplate Pathology and Patient-reported Symptoms for Chronic Low Back Pain Depends on Lumbar Paraspinal Muscle Quality. Spine (Phila Pa 1976). 2019 Jul 15; 44(14):1010-1017. Bailey JF, Fields AJ, Ballatori A, Cohen D, Jain D, Coughlin D, O'Neill C, McCormick Z, Han M, Krug R, Demir-Deviren S, Lotz JC. PMID: 30896590; PMCID: PMC6597281.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    29. Matrix modification for enhancing the transport properties of the human cartilage endplate to improve disc nutrition. PLoS One. 2019; 14(4):e0215218. Dolor A, Sampson SL, Lazar AA, Lotz JC, Szoka FC, Fields AJ. PMID: 30970007; PMCID: PMC6457523.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    30. Nutrient supply and nucleus pulposus cell function: effects of the transport properties of the cartilage endplate and potential implications for intradiscal biologic therapy. Osteoarthritis Cartilage. 2019 06; 27(6):956-964. Wong J, Sampson SL, Bell-Briones H, Ouyang A, Lazar AA, Lotz JC, Fields AJ. PMID: 30721733; PMCID: PMC6536352.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    31. Associations between vertebral body fat fraction and intervertebral disc biochemical composition as assessed by quantitative MRI. J Magn Reson Imaging. 2019 10; 50(4):1219-1226. Krug R, Joseph GB, Han M, Fields A, Cheung J, Mundada M, Bailey J, Rochette A, Ballatori A, McCulloch CE, McCormick Z, O'Neill C, Link TM, Lotz J. PMID: 30701594; PMCID: PMC6667309.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    32. Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones. Nat Commun. 2019 01 11; 10(1):163. Herber CB, Krause WC, Wang L, Bayrer JR, Li A, Schmitz M, Fields A, Ford B, Zhang Z, Reid MS, Nomura DK, Nissenson RA, Correa SM, Ingraham HA. PMID: 30635563; PMCID: PMC6329772.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    33. Effects of dynamic loading on solute transport through the human cartilage endplate. J Biomech. 2019 01 23; 83:273-279. Sampson SL, Sylvia M, Fields AJ. PMID: 30554819; PMCID: PMC6326858.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    34. Contribution of the endplates to disc degeneration. Curr Mol Biol Rep. 2018 Dec; 4(4):151-160. Fields AJ, Ballatori A, Liebenberg EC, Lotz JC. PMID: 30546999; PMCID: PMC6287619.
      View in: PubMed   Mentions: 43  
    35. Tidemark Avulsions are a Predominant Form of Endplate Irregularity. Spine (Phila Pa 1976). 2018 08; 43(16):1095-1101. Berg-Johansen B, Jain D, Liebenberg EC, Fields AJ, Link TM, O'Neill CW, Lotz JC. PMID: 29315127; PMCID: PMC6035893.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    36. FGF and TGFβ signaling link form and function during jaw development and evolution. Dev Biol. 2018 12 01; 444 Suppl 1:S219-S236. Woronowicz KC, Gline SE, Herfat ST, Fields AJ, Schneider RA. PMID: 29753626; PMCID: PMC6239991.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    37. Cartilage Endplate Thickness Variation Measured by Ultrashort Echo-Time MRI Is Associated With Adjacent Disc Degeneration. Spine (Phila Pa 1976). 2018 05 15; 43(10):E592-E600. Berg-Johansen B, Han M, Fields AJ, Liebenberg EC, Lim BJ, Larson PE, Gunduz-Demir C, Kazakia GJ, Krug R, Lotz JC. PMID: 28984733; PMCID: PMC5882595.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    38. Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine. JOR Spine. 2018 Mar; 1(1):e1006. Martin JT, Gullbrand SE, Fields AJ, Purmessur D, Diwan AD, Oxland TR, Chiba K, Guilak F, Hoyland JA, Iatridis JC. PMID: 29770804; PMCID: PMC5944392.
      View in: PubMed   Mentions: 7  
    39. Larger vertebral endplate concavities cause higher failure load and work at failure under high-rate impact loading of rabbit spinal explants. J Mech Behav Biomed Mater. 2018 04; 80:104-110. Dudli S, Enns-Bray W, Pauchard Y, Römmeler A, Fields AJ, Ferguson SJ, Helgason B. PMID: 29414464.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    40. Contributions of Material Properties and Structure to Increased Bone Fragility for a Given Bone Mass in the UCD-T2DM Rat Model of Type 2 Diabetes. J Bone Miner Res. 2018 06; 33(6):1066-1075. Acevedo C, Sylvia M, Schaible E, Graham JL, Stanhope KL, Metz LN, Gludovatz B, Schwartz AV, Ritchie RO, Alliston TN, Havel PJ, Fields AJ. PMID: 29342321; PMCID: PMC6011658.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    41. Structure-function relationships at the human spinal disc-vertebra interface. J Orthop Res. 2018 01; 36(1):192-201. Berg-Johansen B, Fields AJ, Liebenberg EC, Li A, Lotz JC. PMID: 28590060; PMCID: PMC5720932.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    42. Role of Osteoblast Gi Signaling in Age-Related Bone Loss in Female Mice. Endocrinology. 2017 06 01; 158(6):1715-1726. Millard SM, Wang L, Wattanachanya L, O'Carroll D, Fields AJ, Pang J, Kazakia G, Lotz JC, Nissenson RA. PMID: 28407060; PMCID: PMC5460929.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    43. Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis. Sci Rep. 2017 03 22; 7:44618. Fowler TW, Acevedo C, Mazur CM, Hall-Glenn F, Fields AJ, Bale HA, Ritchie RO, Lotz JC, Vail TP, Alliston T. PMID: 28327602; PMCID: PMC5361115.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    44. Pathobiology of Modic changes. Eur Spine J. 2016 11; 25(11):3723-3734. Dudli S, Fields AJ, Samartzis D, Karppinen J, Lotz JC. PMID: 26914098; PMCID: PMC5477843.
      View in: PubMed   Mentions: 142     Fields:    Translation:Humans
    45. Theoretical effects of fully ductile versus fully brittle behaviors of bone tissue on the strength of the human proximal femur and vertebral body. J Biomech. 2015 May 01; 48(7):1264-9. Nawathe S, Yang H, Fields AJ, Bouxsein ML, Keaveny TM. PMID: 25828400.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    46. Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes. J Orthop Res. 2015 May; 33(5):738-46. Fields AJ, Berg-Johansen B, Metz LN, Miller S, La B, Liebenberg EC, Coughlin DG, Graham JL, Stanhope KL, Havel PJ, Lotz JC. PMID: 25641259; PMCID: PMC4408867.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    47. Trabecular plates and rods determine elastic modulus and yield strength of human trabecular bone. Bone. 2015 Mar; 72:71-80. Wang J, Zhou B, Liu XS, Fields AJ, Sanyal A, Shi X, Adams M, Keaveny TM, Guo XE. PMID: 25460571; PMCID: PMC4282941.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    48. Cartilaginous end plates: Quantitative MR imaging with very short echo times-orientation dependence and correlation with biochemical composition. Radiology. 2015 Feb; 274(2):482-9. Fields AJ, Han M, Krug R, Lotz JC. PMID: 25302832; PMCID: PMC4314292.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    49. Comparison of vertebral and intervertebral disc lesions in aging humans and rhesus monkeys. Osteoarthritis Cartilage. 2014 Jul; 22(7):980-5. Bailey JF, Fields AJ, Liebenberg E, Mattison JA, Lotz JC, Kramer PA. PMID: 24821664; PMCID: PMC4105267.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    50. Structural parameters determining the strength of the porcine vertebral body affected by tumours. Comput Methods Biomech Biomed Engin. 2015; 18(8):890-9. Sahli F, Cuellar J, Pérez A, Fields AJ, Campos M, Ramos-Grez J. PMID: 24460089.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    51. Dependence of mechanical properties of trabecular bone on plate-rod microstructure determined by individual trabecula segmentation (ITS). J Biomech. 2014 Feb 07; 47(3):702-8. Zhou B, Liu XS, Wang J, Lu XL, Fields AJ, Guo XE. PMID: 24360196; PMCID: PMC3925244.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    52. Influence of biochemical composition on endplate cartilage tensile properties in the human lumbar spine. J Orthop Res. 2014 Feb; 32(2):245-52. Fields AJ, Rodriguez D, Gary KN, Liebenberg EC, Lotz JC. PMID: 24273192; PMCID: PMC4039641.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    53. Innervation of pathologies in the lumbar vertebral end plate and intervertebral disc. Spine J. 2014 Mar 01; 14(3):513-21. Fields AJ, Liebenberg EC, Lotz JC. PMID: 24139753; PMCID: PMC3945018.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    54. The role of the vertebral end plate in low back pain. Global Spine J. 2013 Jun; 3(3):153-64. Lotz JC, Fields AJ, Liebenberg EC. PMID: 24436866; PMCID: PMC3854605.
      View in: PubMed   Mentions: 96  
    55. Seeing double: a comparison of microstructure, biomechanical function, and adjacent disc health between double- and single-layer vertebral endplates. Spine (Phila Pa 1976). 2012 Oct 01; 37(21):E1310-7. Fields AJ, Sahli F, Rodriguez AG, Lotz JC. PMID: 22781006; PMCID: PMC3461110.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    56. Vertebral fragility and structural redundancy. J Bone Miner Res. 2012 Oct; 27(10):2152-8. Fields AJ, Nawathe S, Eswaran SK, Jekir MG, Adams MF, Papadopoulos P, Keaveny TM. PMID: 22623120; PMCID: PMC3440513.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    57. Micromechanics of the human vertebral body for forward flexion. J Biomech. 2012 Aug 09; 45(12):2142-8. Yang H, Nawathe S, Fields AJ, Keaveny TM. PMID: 22704826; PMCID: PMC3415303.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    58. Trabecular architecture and vertebral fragility in osteoporosis. Curr Osteoporos Rep. 2012 Jun; 10(2):132-40. Fields AJ, Keaveny TM. PMID: 22492119.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    59. Influence of vertical trabeculae on the compressive strength of the human vertebra. J Bone Miner Res. 2011 Feb; 26(2):263-9. Fields AJ, Lee GL, Liu XS, Jekir MG, Guo XE, Keaveny TM. PMID: 20715186; PMCID: PMC3179351.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    60. Mechanisms of initial endplate failure in the human vertebral body. J Biomech. 2010 Dec 01; 43(16):3126-31. Fields AJ, Lee GL, Keaveny TM. PMID: 20817162; PMCID: PMC2991488.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    61. Role of trabecular microarchitecture in whole-vertebral body biomechanical behavior. J Bone Miner Res. 2009 Sep; 24(9):1523-30. Fields AJ, Eswaran SK, Jekir MG, Keaveny TM. PMID: 19338454; PMCID: PMC2730926.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    62. Multi-scale modeling of the human vertebral body: comparison of micro-CT based high-resolution and continuum-level models. Pac Symp Biocomput. 2009; 293-303. Eswaran SK, Fields AJ, Nagarathnam P, Keaveny TM. PMID: 19209709.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    63. Effects of knee simulator loading and alignment variability on predicted implant mechanics: a probabilistic study. J Orthop Res. 2006 Dec; 24(12):2212-21. Laz PJ, Pal S, Fields A, Petrella AJ, Rullkoetter PJ. PMID: 17004268.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
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