Bjoern Schwer, MD, PhD

Title(s)Associate Professor, Neurological Surgery
SchoolSchool of Medicine
Address1450 Third Street, #474
San Francisco CA 94158
Phone415-476-6786
PronounsHe/Him/His
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse awards and honors
    2013Martin D. Abeloff V Scholar, The V Foundation for Cancer Research
    2016Suzanne Marie Haderle and Robert Vincent Haderle Endowed Chair, UCSF
    2017Kimmel Scholar, Sidney Kimmel Foundation
    2021Carol and Gene Ludwig Award for Early Career Research

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Endogenous neuronal DNA double-strand breaks are not sufficient to drive brain aging and neurodegeneration. bioRxiv. 2024 Oct 23. Cohen S, Cheradame L, Pratt KJB, Collins S, Barillas A, Carlson A, Ramani V, Legube G, Villeda SA, Mullins RD, Schwer B. PMID: 39484383; PMCID: PMC11526996.
      View in: PubMed   Mentions:
    2. PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression. Sci Rep. 2024 07 12; 14(1):16074. Schmidt C, Cohen S, Gudenas BL, Husain S, Carlson A, Westelman S, Wang L, Phillips JJ, Northcott PA, Weiss WA, Schwer B. PMID: 38992221; PMCID: PMC11239875.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    3. MDB-32. PRDM6 PROMOTES MEDULLOBLASTOMA FORMATION IN NEUROEPITHELIAL STEM CELLS AND IS A CHROMATIN REPRESSOR BY BINDING TO HISTONE H3 LYSINE 27 TRIMETHYLATION MARKS. Neuro-Oncology. 2024 Jun 18; 26(Supplement_4):0-0. Schmidt SC, Cohen CS, Gudenas GB, Husain HS, Carlson CA, Westelman WS, Wang WL, Phillips PJ, Northcott NP, Weiss WW, Schwer SB. .
      View in: Publisher Site   Mentions:
    4. Type-I-interferon-responsive microglia shape cortical development and behavior. Cell. 2024 Apr 11; 187(8):1936-1954.e24. Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Barron JJ, Wade SD, Cuevas B, Vainchtein ID, Silva NJ, Guajardo R, Xiao Y, Lidsky PV, Wang EY, Rivera BM, Taloma SE, Kim DK, Kaminskaya E, Nakao-Inoue H, Schwer B, Arnold TD, Molofsky AB, Condello C, Andino R, Nowakowski TJ, Molofsky AV. PMID: 38490196; PMCID: PMC11015974.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    5. PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression. bioRxiv. 2023 Aug 31. Schmidt C, Cohen S, Gudenas BL, Husain S, Carlson A, Westelman S, Wang L, Phillips JJ, Northcott PA, Weiss WA, Schwer B. PMID: 37693484; PMCID: PMC10491178.
      View in: PubMed   Mentions:
    6. MDB-09. IMPACT OF PRDM6 ON CHROMATIN ACCESSIBILITY, GENE EXPRESSION, AND MEDULLOBLASTOMA FORMATION. Neuro-Oncology. 2023 Jun 12; 25(Suppl 1):i63-i63. Schmidt SC, Husain HS, Carlson CA, Cohen CS, Westelman WS, Wang WL, Weiss WW, Schwer SB. .
      View in: Publisher Site   Mentions:
    7. Type I interferon responsive microglia shape cortical development and behavior. bioRxiv. 2023 Mar 20. Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Cuevas B, Vainchtein ID, Silva NJ, Xiao Y, Lidsky PV, Wang EY, Taloma SE, Nakao-Inoue H, Schwer B, Andino R, Nowakowski TJ, Molofsky AV. PMID: 35233577; PMCID: PMC8887080.
      View in: PubMed   Mentions:
    8. MODL-32. IMPACT OF PRDM6 ON CHROMATIN ACCESSIBILITY, GENE EXPRESSION, AND MEDULLOBLASTOMA FORMATION. Neuro-Oncology. 2022 Nov 14; 24(Supplement_7):vii297-vii298. Schmidt SC, Husain HS, Carlson CA, Cohen CS, Westelman WS, Wang WL, Weiss WW, Schwer SB. .
      View in: Publisher Site   Mentions:
    9. Relationships between genome-wide R-loop distribution and classes of recurrent DNA breaks in neural stem/progenitor cells. Sci Rep. 2022 08 04; 12(1):13373. Thongthip S, Carlson A, Crossley MP, Schwer B. PMID: 35927309; PMCID: PMC9352722.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    10. Editorial: Genomic Instability and Neurodegeneration. Front Aging Neurosci. 2022; 14:940459. Fuchs J, Schwer B, El-Khamisy SF. PMID: 35754964; PMCID: PMC9214212.
      View in: PubMed   Mentions: 2  
    11. Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice. Neuro Oncol. 2022 02 01; 24(2):259-272. Chuntova P, Hou Y, Naka R, Yamamichi A, Chen T, Goretsky Y, Hatae R, Nejo T, Kohanbash G, Mende AL, Montoya M, Downey KM, Diebold D, Skinner J, Liang HE, Schwer B, Okada H. PMID: 34347086; PMCID: PMC8804899.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    12. Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons. Cell Rep. 2021 09 07; 36(10):109666. Cheng YC, Snavely A, Barrett LB, Zhang X, Herman C, Frost DJ, Riva P, Tochitsky I, Kawaguchi R, Singh B, Ivanis J, Huebner EA, Arvanites A, Oza V, Davidow L, Maeda R, Sakuma M, Grantham A, Wang Q, Chang AN, Pfaff K, Costigan M, Coppola G, Rubin LL, Schwer B, Alt FW, Woolf CJ. PMID: 34496254; PMCID: PMC8462619.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    13. BIOL-11. THE ROLE OF ABERRANT EXPRESSION OF PRDM6 IN THE DEVELOPING CEREBELLUM AND IN GROUP 4 MEDULLOBLASTOMA. Neuro-Oncology. 2021 Jun 1; 23(Suppl 1):i5-i5. Schmidt SC, Carlson CA, Weiss WW, Schwer SB. .
      View in: Publisher Site   Mentions:
    14. OMIC-03. TRANSLATIONAL CONTROL IN MYC AND MYCN MEDULLOBLASTOMA. Neuro-Oncology. 2021 Jun 1; 23(Suppl 1):i37-i37. Schmidt SC, Navickas NA, Zindy ZF, Farmer FD, Ruggero RD, Goodarzi GH, Roussel RM, Schwer SB, Weiss WW. .
      View in: Publisher Site   Mentions:
    15. TMOD-28. NEW APPROACHES FOR ELUCIDATING MEDULLOBLASTOMA DEVELOPMENT VIA HINDBRAIN BLASTOCYST COMPLEMENTATION. Neuro-Oncology. 2020 Nov 9; 22(Supplement_2):ii233-ii234. Schmidt SC, Carlson CA, Weiss WW, Schwer SB. .
      View in: Publisher Site   Mentions:
    16. Direct analysis of brain phenotypes via neural blastocyst complementation. Nat Protoc. 2020 10; 15(10):3154-3181. Dai HQ, Liang Z, Chang AN, Chapdelaine-Williams AM, Alvarado B, Pollen AA, Alt FW, Schwer B. PMID: 32778838; PMCID: PMC7685531.
      View in: PubMed   Mentions: 4     Fields:    
    17. Neural blastocyst complementation enables mouse forebrain organogenesis. Nature. 2018 11; 563(7729):126-130. Chang AN, Liang Z, Dai HQ, Chapdelaine-Williams AM, Andrews N, Bronson RT, Schwer B, Alt FW. PMID: 30305734; PMCID: PMC6588192.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    18. DNA double-strand breaks as drivers of neural genomic change, function, and disease. DNA Repair (Amst). 2018 11; 71:158-163. Alt FW, Schwer B. PMID: 30195640; PMCID: PMC6340756.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    19. Three classes of recurrent DNA break clusters in brain progenitors identified by 3D proximity-based break joining assay. Proc Natl Acad Sci U S A. 2018 02 20; 115(8):1919-1924. Wei PC, Lee CS, Du Z, Schwer B, Zhang Y, Kao J, Zurita J, Alt FW. PMID: 29432181; PMCID: PMC5828622.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    20. Sirt4 is a mitochondrial regulator of metabolism and lifespan in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):1564-1569. Wood JG, Schwer B, Wickremesinghe PC, Hartnett DA, Burhenn L, Garcia M, Li M, Verdin E, Helfand SL. PMID: 29378963; PMCID: PMC5816209.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    21. Editorial: DNA damage & immunity. Mech Ageing Dev. 2017 07; 165(Pt A):1-2. Garinis GA, Schwer B, Schumacher B. PMID: 28445698; PMCID: PMC5544113.
      View in: PubMed   Mentions: 1     Fields:    
    22. Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer. Genome Editing in Neurosciences. 2017 Jan 1; 63-72. Alt AF, Wei WP, Schwer SB. .
      View in: Publisher Site   Mentions:
    23. Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2258-63. Schwer B, Wei PC, Chang AN, Kao J, Du Z, Meyers RM, Alt FW. PMID: 26873106; PMCID: PMC4776469.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    24. Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells. Cell. 2016 Feb 11; 164(4):644-55. Wei PC, Chang AN, Kao J, Du Z, Meyers RM, Alt FW, Schwer B. PMID: 26871630; PMCID: PMC4752721.
      View in: PubMed   Mentions: 137     Fields:    
    25. IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2644-9. Gostissa M, Schwer B, Chang A, Dong J, Meyers RM, Marecki GT, Choi VW, Chiarle R, Zarrin AA, Alt FW. PMID: 24550291; PMCID: PMC3932927.
      View in: PubMed   Mentions: 14     Fields:    
    26. SIRT6 modulates paclitaxel and epirubicin resistance and survival in breast cancer. Carcinogenesis. 2013 Jul; 34(7):1476-86. Khongkow M, Olmos Y, Gong C, Gomes AR, Monteiro LJ, Yagüe E, Cavaco TB, Khongkow P, Man EP, Laohasinnarong S, Koo CY, Harada-Shoji N, Tsang JW, Coombes RC, Schwer B, Khoo US, Lam EW. PMID: 23514751.
      View in: PubMed   Mentions: 73     Fields:    
    27. Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2. PLoS Genet. 2013; 9(2):e1003298. Shi W, Bain AL, Schwer B, Al-Ejeh F, Smith C, Wong L, Chai H, Miranda MS, Ho U, Kawaguchi M, Miura Y, Finnie JW, Wall M, Heierhorst J, Wicking C, Spring KJ, Alt FW, Khanna KK. PMID: 23408915; PMCID: PMC3567186.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    28. Mechanisms of programmed DNA lesions and genomic instability in the immune system. Cell. 2013 Jan 31; 152(3):417-29. Alt FW, Zhang Y, Meng FL, Guo C, Schwer B. PMID: 23374339; PMCID: PMC4382911.
      View in: PubMed   Mentions: 236     Fields:    
    29. Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining. Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):2234-9. Oksenych V, Kumar V, Liu X, Guo C, Schwer B, Zha S, Alt FW. PMID: 23345432; PMCID: PMC3568359.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    30. Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1). Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2473-8. Boboila C, Oksenych V, Gostissa M, Wang JH, Zha S, Zhang Y, Chai H, Lee CS, Jankovic M, Saez LM, Nussenzweig MC, McKinnon PJ, Alt FW, Schwer B. PMID: 22308491; PMCID: PMC3289296.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    31. Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2455-60. Oksenych V, Alt FW, Kumar V, Schwer B, Wesemann DR, Hansen E, Patel H, Su A, Guo C. PMID: 22308489; PMCID: PMC3289340.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    32. Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks. Adv Immunol. 2012; 116:1-49. Boboila C, Alt FW, Schwer B. PMID: 23063072.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    33. SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism. Cold Spring Harb Symp Quant Biol. 2011; 76:267-77. Hirschey MD, Shimazu T, Huang JY, Schwer B, Verdin E. PMID: 22114326.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    34. SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Mol Cell. 2011 Oct 21; 44(2):177-90. Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stancáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, Laakso M, Alt FW, Newgard CB, Farese RV, Kahn CR, Verdin E. PMID: 21856199; PMCID: PMC3563434.
      View in: PubMed   Mentions: 378     Fields:    Translation:HumansAnimalsCells
    35. The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nat Immunol. 2011 Jun; 12(6):536-43. Ise W, Kohyama M, Schraml BU, Zhang T, Schwer B, Basu U, Alt FW, Tang J, Oltz EM, Murphy TL, Murphy KM. PMID: 21572431; PMCID: PMC3117275.
      View in: PubMed   Mentions: 184     Fields:    
    36. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab. 2010 Dec 01; 12(6):654-61. Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E. PMID: 21109197; PMCID: PMC3310379.
      View in: PubMed   Mentions: 250     Fields:    
    37. Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21790-4. Schwer B, Schumacher B, Lombard DB, Xiao C, Kurtev MV, Gao J, Schneider JI, Chai H, Bronson RT, Tsai LH, Deng CX, Alt FW. PMID: 21098266; PMCID: PMC3003110.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    38. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature. 2010 Mar 04; 464(7285):121-5. Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV, Alt FW, Kahn CR, Verdin E. PMID: 20203611; PMCID: PMC2841477.
      View in: PubMed   Mentions: 791     Fields:    
    39. Calorie restriction alters mitochondrial protein acetylation. Aging Cell. 2009 Sep; 8(5):604-6. Schwer B, Eckersdorff M, Li Y, Silva JC, Fermin D, Kurtev MV, Giallourakis C, Comb MJ, Alt FW, Lombard DB. PMID: 19594485; PMCID: PMC2752488.
      View in: PubMed   Mentions: 122     Fields:    
    40. Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation. Biochem Soc Trans. 2009 Jun; 37(Pt 3):561-8. Basu U, Franklin A, Schwer B, Cheng HL, Chaudhuri J, Alt FW. PMID: 19442251; PMCID: PMC3540414.
      View in: PubMed   Mentions: 3     Fields:    
    41. Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2717-22. Cheng HL, Vuong BQ, Basu U, Franklin A, Schwer B, Astarita J, Phan RT, Datta A, Manis J, Alt FW, Chaudhuri J. PMID: 19196992; PMCID: PMC2650332.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    42. Conserved metabolic regulatory functions of sirtuins. Cell Metab. 2008 Feb; 7(2):104-12. Schwer B, Verdin E. PMID: 18249170.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansAnimalsCells
    43. SIRT6 in DNA repair, metabolism and ageing. J Intern Med. 2008 Feb; 263(2):128-41. Lombard DB, Schwer B, Alt FW, Mostoslavsky R. PMID: 18226091; PMCID: PMC2486832.
      View in: PubMed   Mentions: 61     Fields:    
    44. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol Cell Biol. 2007 Dec; 27(24):8807-14. Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV, Weissman S, Verdin E, Schwer B. PMID: 17923681; PMCID: PMC2169418.
      View in: PubMed   Mentions: 571     Fields:    Translation:AnimalsCells
    45. Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. J Biol Chem. 2007 Nov 16; 282(46):33583-33592. Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E. PMID: 17715127.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansCells
    46. Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10224-10229. Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E. PMID: 16788062; PMCID: PMC1502439.
      View in: PubMed   Mentions: 291     Fields:    Translation:HumansAnimalsCells
    47. The Class III Protein Deacetylases. Histone Deacetylases. 2006 Jan 1; 237-268. Schwer SB, North NB, Ahuja AN, Marshall MB, Verdin VE. .
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    48. Preparation of enzymatically active recombinant class III protein deacetylases. Methods. 2005 Aug; 36(4):338-45. North BJ, Schwer B, Ahuja N, Marshall B, Verdin E. PMID: 16091304.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    49. Targeting of hepatitis C virus core protein to mitochondria through a novel C-terminal localization motif. J Virol. 2004 Aug; 78(15):7958-68. Schwer B, Ren S, Pietschmann T, Kartenbeck J, Kaehlcke K, Bartenschlager R, Yen TS, Ott M. PMID: 15254168; PMCID: PMC446112.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    50. Release and intercellular transfer of cell surface CD81 via microparticles. J Immunol. 2002 Nov 15; 169(10):5531-7. Fritzsching B, Schwer B, Kartenbeck J, Pedal A, Horejsi V, Ott M. PMID: 12421929.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    51. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol. 2002 Aug 19; 158(4):647-57. Schwer B, North BJ, Frye RA, Ott M, Verdin E. PMID: 12186850; PMCID: PMC2174009.
      View in: PubMed   Mentions: 259     Fields:    Translation:HumansCells
    52. A new twist on RNA helicases: DExH/D box proteins as RNPases. Nat Struct Biol. 2001 Feb; 8(2):113-6. Schwer B. PMID: 11175897.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    53. RNA helicase dynamics in pre-mRNA splicing. EMBO J. 2000 Dec 01; 19(23):6582-91. Schwer B, Meszaros T. PMID: 11101530; PMCID: PMC305851.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    54. Interaction of the yeast DExH-box RNA helicase prp22p with the 3' splice site during the second step of nuclear pre-mRNA splicing. Nucleic Acids Res. 2000 Mar 15; 28(6):1313-21. McPheeters DS, Schwer B, Muhlenkamp P. PMID: 10684925; PMCID: PMC111051.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    55. Trans-complementation of the second step of pre-mRNA splicing by exogenous 5' exons. RNA. 1999 Jul; 5(7):876-82. Chanfreau G, Gouyette C, Schwer B, Jacquier A. PMID: 10411131; PMCID: PMC1369812.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    56. Mutational analysis of the yeast DEAH-box splicing factor Prp16. Genetics. 1998 Jun; 149(2):807-15. Hotz HR, Schwer B. PMID: 9611193; PMCID: PMC1460209.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    57. Accelerated mRNA decay in conditional mutants of yeast mRNA capping enzyme. Nucleic Acids Res. 1998 May 01; 26(9):2050-7. Schwer B, Mao X, Shuman S. PMID: 9547258; PMCID: PMC147543.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    58. Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing. EMBO J. 1998 Apr 01; 17(7):2086-94. Schwer B, Gross CH. PMID: 9524130; PMCID: PMC1170553.
      View in: PubMed   Mentions: 120     Fields:    Translation:AnimalsCells
    59. Effects of deletion mutations in the yeast Ces1 protein on cell growth and morphology and on high copy suppression of mutations in mRNA capping enzyme and translation initiation factor 4A. Nucleic Acids Res. 1998 Feb 01; 26(3):803-9. Schwer B, Linder P, Shuman S. PMID: 9443973; PMCID: PMC147332.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    60. Functional and physical interaction between the yeast splicing factors Slu7 and Prp18. Nucleic Acids Res. 1997 Jun 01; 25(11):2146-52. Zhang X, Schwer B. PMID: 9153314; PMCID: PMC146706.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    61. Requirement for SLU7 in yeast pre-mRNA splicing is dictated by the distance between the branchpoint and the 3' splice site. RNA. 1996 Jul; 2(7):707-17. Brys A, Schwer B. PMID: 8756413; PMCID: PMC1369409.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    62. Conditional inactivation of mRNA capping enzyme affects yeast pre-mRNA splicing in vivo. RNA. 1996 Jun; 2(6):574-83. Schwer B, Shuman S. PMID: 8718686; PMCID: PMC1369396.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    63. SLU7 and a novel activity, SSF1, act during the PRP16-dependent step of yeast pre-mRNA splicing. EMBO J. 1995 Aug 15; 14(16):4001-9. Ansari A, Schwer B. PMID: 7664739; PMCID: PMC394478.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    64. A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis. EMBO J. 1992 Dec; 11(13):5033-9. Schwer B, Guthrie C. PMID: 1464325; PMCID: PMC556981.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    65. Vaccinia virus late transcripts generated in vitro have a poly(A) head. EMBO J. 1988 Apr; 7(4):1183-90. Schwer B, Stunnenberg HG. PMID: 3402436; PMCID: PMC454454.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
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