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Christian Cordano, MD, PhD

Title(s)Specialist, Neurology
SchoolSchool of Medicine
ORCID ORCID Icon0000-0002-1413-0442 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    Genoa University, ItalyMedical School2007
    Genoa University, ItalyResidency in Neurology2013
    Genoa University, ItalyPostdoctoral Fellowship 2014Neuroimmunology
    University of California, San Francisco, California, USPostdoctoral Fellowship 2016Neuro Ophtalmology
    Genoa University, ItalyPhD2017Molecular and Cellular Pathology of Aging Related Diseases
    Collapse Awards and Honors
    Italian Multiple Sclerosis Foundation (FISM)2014  - 2016Training Fellowship
    European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)2015Travel Grant
    Italian Multiple Sclerosis Foundation (FISM)2016Best Poster at Italian MS Foundation Congress
    Italian Society of Ophthalmology (SOI)2016Best Scientific Research Project: 2nd place
    Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 20172017Educational Grant Award
    Italian Society of Ophthalmology (SOI)2017Best Scientific Research Project: 1st place

    Collapse Overview 
    Collapse Overview
    Dr. Cordano completed his MD followed by a residency in Neurology at the University of Genoa, in Italy. This was followed by a fellowship in Neuroimmunology at the University of Genoa. During his residency and fellowship in Genoa he worked with Professor Antonio Uccelli for six years, carrying out clinical trials in MS that included the use of OCT and VEP to monitor disease.

    Dr. Cordano subsequently decided to focus his career on MS research, coupling his dual passions for neuro-ophthalmology and neuroimmunology. He joined Dr. Ari Green´s Lab at UCSF as a Postdoctoral Research Fellow in August 2014, funded by a fellowship from FISM (Italian Multiple Sclerosis Foundation).

    His work is focused on visual electrophysiologic alteration in Experimental Autoimmune Encephalomyelitis models, trying to characterize the course of electrophysiologic alterations and neuronal injury following demyelination.
    He completed his PhD in the Department of Experimental Medicine at the University of Genoa in April 2017, and will also complete a degree in Economics. Dr. Cordano grew up in Genoa. In his free time, he loves to travel, cheer on his soccer team (Genoa), and read comics and classics.

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sheehy CK, Bensinger ES, Romeo A, Rani L, Stepien-Bernabe N, Shi B, Helft Z, Putnam N, Cordano C, Gelfand JM, Bove R, Stevenson SB, Green AJ. Fixational microsaccades: A quantitative and objective measure of disability in multiple sclerosis. Mult Scler. 2020 Feb 07; 1352458519894712. PMID: 32031464.
      View in: PubMed
    2. Cruz-Herranz A, Dietrich M, Hilla AM, Yiu HH, Levin MH, Hecker C, Issberner A, Hallenberger A, Cordano C, Lehmann-Horn K, Balk LJ, Aktas O, Ingwersen J, von Gall C, Hartung HP, Zamvil SS, Fischer D, Albrecht P, Green AJ. Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2019 Nov 04; 16(1):203. PMID: 31684959.
      View in: PubMed
    3. Cellerino M, Cordano C, Boffa G, Bommarito G, Petracca M, Sbragia E, Novi G, Lapucci C, Capello E, Uccelli A, Inglese M. Relationship between retinal inner nuclear layer, age, and disease activity in progressive MS. Neurol Neuroimmunol Neuroinflamm. 2019 Sep; 6(5). PMID: 31454778.
      View in: PubMed
    4. Cordano C, Nourbakhsh B, Devereux M, Damotte V, Bennett D, Hauser SL, Cree BAC, Gelfand JM, Green AJ. pRNFL as a marker of disability worsening in the medium/long term in patients with MS. Neurol Neuroimmunol Neuroinflamm. 2019 03; 6(2):e533. PMID: 30697584.
      View in: PubMed
    5. Orrù CD, Soldau K, Cordano C, Llibre-Guerra J, Green AJ, Sanchez H, Groveman BR, Edland SD, Safar JG, Lin JH, Caughey B, Geschwind MD, Sigurdson CJ. Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients. MBio. 2018 11 20; 9(6). PMID: 30459197.
      View in: PubMed
    6. Caranci G, Cordano C, Giannini E, Bandini F. Acquired Hepatocerebral Degeneration in the Absence of Portosystemic Shunting. J Clin Neurol. 2019 Jan; 15(1):128-129. PMID: 30375762.
      View in: PubMed
    7. Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green AJ, Nave KA, Franklin RJ, Rowitch DH. Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity. Elife. 2018 09 11; 7. PMID: 30204081.
      View in: PubMed
    8. Nourbakhsh B, Cordano C, Renthal W. Determining the Etiology of Internuclear Ophthalmoplegia in a Patient with a Cardiac Pacemaker and Complex Neurological Presentation. J Clin Neurol. 2018 Oct; 14(4):574-576. PMID: 30198234.
      View in: PubMed
    9. Cordano C, Armezzani A, Veroni J, Pardini M, Sassos D, Infante MT, Tacchino A, Lapucci C, Cellerino M, Calabrò V, Ciullo L, Nourbakhsh B. Osteopathic Manipulative Therapy and Multiple Sclerosis: A Proof-of-Concept Study. J Am Osteopath Assoc. 2018 Aug 01; 118(8):531-536. PMID: 30073336.
      View in: PubMed
    10. Solmaz V, Ozlece HK, Him A, Günes A, Cordano C, Aksoy D, Çelik Y. Evaluation of the association between sexual dysfunction and demyelinating plaque location and number in female multiple sclerosis patients. Neurol Res. 2018 Aug; 40(8):683-688. PMID: 29663848.
      View in: PubMed
    11. Cordano C, Caverzasi E, Spigno L, De Maria A, Bandini F. MRI Findings in Varicella Zoster Trigeminal Neuritis Without Rash. Headache. 2018 05; 58(5):764-765. PMID: 29399793.
      View in: PubMed
    12. Tacchino A, Saiote C, Brichetto G, Bommarito G, Roccatagliata L, Cordano C, Battaglia MA, Mancardi GL, Inglese M. Motor Imagery as a Function of Disease Severity in Multiple Sclerosis: An fMRI Study. Front Hum Neurosci. 2017; 11:628. PMID: 29375340.
      View in: PubMed
    13. Bischof A, Caverzasi E, Cordano C, Hauser SL, Henry RG. Advances in Imaging Multiple Sclerosis. Semin Neurol. 2017 10; 37(5):538-545. PMID: 29207413.
      View in: PubMed
    14. Cordano C, López GY, Bollen AW, Nourbakhsh B. Occipital Headache in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS). Headache. 2018 03; 58(3):458-459. PMID: 29193048.
      View in: PubMed
    15. Petzold A, Balcer LJ, Calabresi PA, Costello F, Frohman TC, Frohman EM, Martinez-Lapiscina EH, Green AJ, Kardon R, Outteryck O, Paul F, Schippling S, Vermersch P, Villoslada P, Balk LJ. Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis. Lancet Neurol. 2017 10; 16(10):797-812. PMID: 28920886.
      View in: PubMed
    16. Christian Cordano, Bardia Nourbakhsh, Ethan Brown, Christine Glastonbury. Extensive Involvement of Multiple Cranial and Spinal Nerves in Lymphomatous Meningitis – ERRATUM. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 2017 Sep 1; 44(5):627-627.
      View in: Publisher Site
    17. Cordano C, Nourbakhsh B, Brown E, Glastonbury C. Extensive Involvement of Multiple Cranial and Spinal Nerves in Lymphomatous Meningitis. Can J Neurol Sci. 2017 09; 44(5):599-600. PMID: 28482940.
      View in: PubMed
    18. Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E, Mesulam MM, Bogyo MS, Mackenzie IR, Staropoli JF, Cotman SL, Huang EJ, Gan L, Green AJ. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Sci Transl Med. 2017 04 12; 9(385). PMID: 28404863.
      View in: PubMed
    19. Cordano C, Alessandria G, Leonardi A, Cellerino M, Nourbakhsh B, Nobili F, Bandini F. Homonymous hemianopia as the first sign of posterior cortical atrophy. J Neurol Sci. 2017 Feb 15; 373:38-40. PMID: 28131221.
      View in: PubMed
    20. Saiote C, Tacchino A, Brichetto G, Roccatagliata L, Bommarito G, Cordano C, Battaglia M, Mancardi GL, Inglese M. Resting-state functional connectivity and motor imagery brain activation. Hum Brain Mapp. 2016 11; 37(11):3847-3857. PMID: 27273577.
      View in: PubMed
    21. Petracca M, Cordano C, Cellerino M, Button J, Krieger S, Vancea R, Ghassemi R, Farrell C, Miller A, Calabresi PA, Lublin F, Inglese M. Retinal degeneration in primary-progressive multiple sclerosis: A role for cortical lesions? Mult Scler. 2017 01; 23(1):43-50. PMID: 26993116.
      View in: PubMed
    22. Martinez-Lapiscina EH, Arnow S, Wilson JA, Saidha S, Preiningerova JL, Oberwahrenbrock T, Brandt AU, Pablo LE, Guerrieri S, Gonzalez I, Outteryck O, Mueller AK, Albrecht P, Chan W, Lukas S, Balk LJ, Fraser C, Frederiksen JL, Resto J, Frohman T, Cordano C, Zubizarreta I, Andorra M, Sanchez-Dalmau B, Saiz A, Bermel R, Klistorner A, Petzold A, Schippling S, Costello F, Aktas O, Vermersch P, Oreja-Guevara C, Comi G, Leocani L, Garcia-Martin E, Paul F, Havrdova E, Frohman E, Balcer LJ, Green AJ, Calabresi PA, Villoslada P. Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study. Lancet Neurol. 2016 May; 15(6):574-84. PMID: 27011339.
      View in: PubMed
    23. Arnaldi D, Cordano C, De Carli F, Accardo J, Ferrara M, Picco A, Tamburini T, Brugnolo A, Abbruzzese G, Nobili F. Parkinson's Disease Sleep Scale 2: application in an Italian population. Neurol Sci. 2016 Feb; 37(2):283-8. PMID: 26520846.
      View in: PubMed
    24. Tinazzi M, Fasano A, Geroin C, Morgante F, Ceravolo R, Rossi S, Thomas A, Fabbrini G, Bentivoglio A, Tamma F, Cossu G, Modugno N, Zappia M, Volontè MA, Dallocchio C, Abbruzzese G, Pacchetti C, Marconi R, Defazio G, Canesi M, Cannas A, Pisani A, Mirandola R, Barone P, Vitale C. Pisa syndrome in Parkinson disease: An observational multicenter Italian study. Neurology. 2015 Nov 17; 85(20):1769-79. PMID: 26491088.
      View in: PubMed
    25. Pardini M, Cordano C, Guida S, Grafman J, Krueger F, Sassos D, Massucco D, Abate L, Yaldizli Ö, Serrati C, Amore M, Mattei C, Cocito L, Emberti Gialloreti L. Prevalence and cognitive underpinnings of isolated apathy in young healthy subjects. J Affect Disord. 2016 Jan 01; 189:272-5. PMID: 26454331.
      View in: PubMed
    26. Parodi B, Rossi S, Morando S, Cordano C, Bragoni A, Motta C, Usai C, Wipke BT, Scannevin RH, Mancardi GL, Centonze D, Kerlero de Rosbo N, Uccelli A. Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS. Acta Neuropathol. 2015 Aug; 130(2):279-95. PMID: 25920452.
      View in: PubMed
    27. Cordano C, Pardini M, Cellerino M, Schenone A, Marino F, Cosentino M. Levodopa-induced neutropenia. Parkinsonism Relat Disord. 2015 Apr; 21(4):423-5. PMID: 25707301.
      View in: PubMed
    28. Benedetta Parodi, Christian Cordano, Sara Morando, Alberto Bragoni, Debora Giunti, Cesare Usai, Diego Centonze, Nicole Kerlero De Rosbo, Robert H. Scannevin, Antonio Uccelli. Monomethyl fumarate inhibits the NFkB pathway and pro-inflammatory cytokine expression in microglia through HCA2 signaling via the AMPK/Sirt axis. Journal of Neuroimmunology. 2014 Oct 1; 275(1-2):167-168.
      View in: Publisher Site
    29. Cordano C, Traverso E, Calabrò V, Borzone C, Stara S, Marchese R, Marinelli L. Recurring hyperammonemic encephalopathy induced by bacteria usually not producing urease. BMC Res Notes. 2014 May 31; 7:324. PMID: 24884855.
      View in: PubMed
    30. Fornaro M, Bandini F, Cestari L, Cordano C, Ogliastro C, Albano C, De Berardis D, Martino M, Escelsior A, Rocchi G, Fornaro P, De Pasquale C. Electroretinographic modifications induced by agomelatine: a novel avenue to the understanding of the claimed antidepressant effect of the drug? Neuropsychiatr Dis Treat. 2014; 10:907-14. PMID: 24899809.
      View in: PubMed
    31. Giunti D, Parodi B, Cordano C, Uccelli A, Kerlero de Rosbo N. Can we switch microglia's phenotype to foster neuroprotection? Focus on multiple sclerosis. Immunology. 2014 Mar; 141(3):328-39. PMID: 24116890.
      View in: PubMed
    32. Pardini M, Cordano C, Benassi F, Mattei C, Sassos D, Guida S, Serrati C, Primavera A, Amore M, Cocito L, Emberti Gialloreti L. Agomelatine but not melatonin improves fatigue perception: a longitudinal proof-of-concept study. Eur Neuropsychopharmacol. 2014 Jun; 24(6):939-44. PMID: 24636462.
      View in: PubMed
    33. Valbusa A, Ingrassia S, Rosa GM, Infante MT, Schenone A, Montecucco F, Cordano C. Takotsubo cardiomyopathy and torsade de pointes in myasthenic crisis: be aware of QT prolongation. Am J Emerg Med. 2013 Dec; 31(12):1717-8. PMID: 24161204.
      View in: PubMed
    34. Christian Cordano, Nicole Kerlero de Rosbo, Antonio Uccelli. 10 Mesenchymal stem cells as a strategy for the treatment of multiple sclerosis and other diseases of the central nervous system. Stem Cell-Dependent Therapies. 2013 Jan 16; 185-210.
      View in: Publisher Site
    35. Fornaro M, Bandini F, Ogliastro C, Cordano C, Martino M, Cestari L, Escelsior A, Rocchi G, Colicchio S, Perugi G. Electroretinographic assessment in major depressed patients receiving duloxetine: might differences between responders and non-responders indicate a differential biological background? J Affect Disord. 2011 Dec; 135(1-3):154-9. PMID: 21820182.
      View in: PubMed
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