Joseph "Mike" McCune, MD, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Avenue, #223
San Francisco CA 94110
Phone628-206-8102
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    Collapse Biography 
    Collapse Education and Training
    Stanford University Medical College, Palo Alto, CAPost-Doc Fellow/Scholar1988Pathology
    University of California, San Francisco Clinical Fellowship 1986Infectious Disease
    University of California, San FranciscoResidency 1984Internal Medicine
    Cornell University Medical College, New York, NYM.D.1982Medicine
    The Rockefeller University, New York, NYPh.D.1981Cell Biology/Immunology
    Harvard College, Cambridge, MAA.B.1975Biochemistry

    Collapse Overview 
    Collapse Overview
    Joseph ("Mike") McCune is a professor of medicine at the University of California, San Francisco (UCSF). He received his AB degree from Harvard College in 1975, his PhD degree from Rockefeller University in 1981, and his MD degree from Cornell University Medical College in 1982. He completed his residency in internal medicine in 1984 and did fellowship training in infectious diseases at UCSF. He is board certified in internal medicine.

    The McCune lab has been involved for many years in the analysis of HIV pathogenesis, prevention, treatment, and cure. Dr. McCune started to treat patients with HIV disease as a resident in internal medicine at UCSF in 1982 and has been involved in the HIV/AIDS research field ever since. This work included postdoctoral studies at Stanford, exploring the fusogenic properties of the HIV envelope protein and developing the first humanized mouse model (the SCID-hu mouse) capable of multilineage human hematopoiesis and receptive to infection with primary isolates of HIV. He then co-founded the companies SyStemix (in 1988) and Progenesys (and 1991), serving as Scientific Director and leading research efforts to find better ways – including antiviral medications and hematopoietic stem cell-based gene therapy – to treat HIV disease. In 1995, Dr. McCune returned to academia, first as an investigator at the Gladstone Institute of Virology and Immunology and then (from 2006-2016) as the Chief of the Division of Experimental Medicine (which he founded) at UCSF. Concomitantly, he was the founding PI (and Senior Associate Dean) of the Clinical and Translational Sciences Institute at UCSF (from 2005-08). In recent years, he has helped to form multidisciplinary, collaborative research teams to find a cure for HIV disease. Throughout this time, he has actively mentored graduate students and postdoctoral fellows, many of whom have gone on to successful careers in academia or biotech/pharma.

    Dr. McCune’s studies have led to the publication of over 200 peer-reviewed articles, and he is the holder of 20 patents and inventions. He is a member of many scientific and professional societies, including the American Society for Clinical Investigation, the American Association of Physicians, and the Henry Kunkel Society. He has served on the editorial boards of Virology and the Journal of the Acquired Immune Deficiency Syndrome. He was awarded the Elizabeth Glaser Pediatric AIDS Foundation Scientist Award in 1996, the Burroughs Wellcome Fund Clinical Scientist Award in Translational Research in 2000, a MERIT Award from the NIH in 2001, the NIH Director’s Pioneer Award in 2004, and the Holly Smith Award for Exceptional Service to the School of Medicine in 2016. He was also selected to give the UCSF Academic Senate Faculty Research Lecture (on Translational Science) in 2013.
    Collapse Global Health Equity

    Collapse Research 
    Collapse Research Activities and Funding
    Interferon-independent mechanisms of malaria restriction by helper T cells
    NIH R21AI114916Sep 1, 2015 - Aug 31, 2017
    Role: Principal Investigator
    The impact of TB co-infection on the reservoir of persistent HIV in vivo
    NIH R21AI116295Aug 1, 2015 - Jul 31, 2018
    Role: Principal Investigator
    Timing of ART and homeostasis of the persistent HIV reservoir in the adult
    NIH R01AI116368Feb 4, 2015 - Jan 31, 2021
    Role: Principal Investigator
    Novel flow cytometry-based assay for HIV-infected cells
    NIH R21AI110143Dec 1, 2013 - Nov 30, 2015
    Role: Principal Investigator
    Layering of the human immune system, viral infections, and childhood asthma
    NIH R01AI100082Aug 21, 2012 - Jul 31, 2017
    Role: Principal Investigator
    DARE: Delaney AIDS Research Enterprise to find a cure.
    NIH U19AI096109Jul 8, 2011 - Jun 30, 2017
    Role: Principal Investigator
    Human immune system layering and the neonatal response to vaccines
    NIH R21AI094009Mar 1, 2011 - Feb 28, 2014
    Role: Principal Investigator
    The Impact of Tolerance in the Newborn on Lentiviral Infection
    NIH R01AI090677Jul 2, 2010 - Jun 30, 2015
    Role: Principal Investigator
    Bay Area Hepatitis C Cooperative Research Center
    NIH U19AI088790Jun 15, 2010 - May 31, 2016
    Role: Principal Investigator
    Interruption of maternal-fetal transmission of HIV
    NIH R01AI084109Sep 5, 2009 - Aug 31, 2014
    Role: Principal Investigator
    HIV Proteomic Center for Host-Viral Response Characterization
    NIH P01DA026134Sep 30, 2008 - May 31, 2012
    Role: Co-Investigator
    Clinical and Transtional Science Institute
    NIH KL2RR024130Sep 30, 2006 - Jun 30, 2016
    Role: Principal Investigator
    Clinical and Transtional Science Institute
    NIH TL1RR024129Sep 30, 2006 - Jun 30, 2016
    Role: Principal Investigator
    Clinical and Translational Science Institute
    NIH UL1RR024131Sep 30, 2006 - Jun 30, 2016
    Role: Principal Investigator
    Anti-Gag Antibodies and Enhancement of Lentiviral Disease Progression
    NIH R21AI068583Jul 1, 2006 - Jun 30, 2009
    Role: Principal Investigator
    NIH Director's Pioneer Award (RMI)
    NIH DP1OD000329Sep 30, 2004 - Jul 31, 2010
    Role: Principal Investigator
    Beckman Coulter BioMek 2000 Workstation and Accessories
    NIH S10RR016959Apr 1, 2002 - Mar 31, 2003
    Role: Principal Investigator
    MOFLO TM HIGH PERFORMANCE FLOW CYTOMETER
    NIH S10RR013768Apr 1, 2000 - Mar 31, 2002
    Role: Principal Investigator
    Assessing Laboratory Correlates of Immune Protection
    NIH R01AI047062Feb 1, 2000 - Dec 31, 2008
    Role: Principal Investigator
    HUMAN IMMUNE CELL MATURATION DURING ONTOGENY AND INFECTI
    NIH P01AI045865Sep 30, 1999 - Aug 31, 2003
    Role: Co-Investigator
    Thymic Function in Adults With HIV-1 Disease
    NIH U01AI043864Mar 1, 1999 - Mar 31, 2010
    Role: Principal Investigator
    THYMIC FUNCTION IN ADULTS WITH HIV1 DISEASE
    NIH R01AI043864Mar 1, 1999 - Feb 28, 2003
    Role: Principal Investigator
    SCID-HU ANIMAL MODEL FOR EVALUATING HIV THERAPIES
    NIH N01AI065309Jul 1, 1996 - Sep 29, 2000
    Role: Principal Investigator
    HIV EFFECTS ON THE CENTRAL HEMATOLYMPHOID SYSTEM
    NIH R37AI040312Apr 1, 1996 - Feb 28, 2012
    Role: Principal Investigator
    HIV EFFECTS ON THE CENTRAL HEMATOLYMPHOID SYSTEM IN VIVO
    NIH R01AI040312Apr 1, 1996 - Jul 31, 2000
    Role: Principal Investigator
    DISCOVERY AND DEVELOPMENT OF THERAPEUTIC COMPOUNDS
    NIH R13CA060157Mar 18, 1993 - Mar 17, 1994
    Role: Principal Investigator
    HIV INFECTION IN THE SCID-HU MOUSE
    NIH R01AI029323Sep 30, 1989 - Jul 31, 1995
    Role: Principal Investigator
    California National Primate Research Center
    NIH P51RR000169Jun 1, 1975 - Apr 30, 2015
    Role: Co-Investigator
    General Clinical Research Center
    NIH M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Erratum to: Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner? Pathog Immun. 2023; 8(2):179-222. Harper J, Betts MR, Lichterfeld M, Müller-Trutwin M, Margolis D, Bar KJ, Li JZ, McCune JM, Lewin SR, Kulpa D, Ávila-Ríos S, Diallo DD, Lederman MM, Paiardini M. PMID: 38505662; PMCID: PMC10949969.
      View in: PubMed   Mentions:
    2. Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner? Pathog Immun. 2023; 8(2):115-157. Harper J, Betts MR, Lichterfeld M, Müller-Trutwin M, Margolis D, Bar KJ, Li JZ, McCune JM, Lewin SR, Kulpa D, Diallo DD, Lederman MM, Paiardini M. PMID: 38455668; PMCID: PMC10919397.
      View in: PubMed   Mentions:
    3. The promise of a "cure" for HIV: implications for the future of PEPFAR-supported HIV programmes. J Int AIDS Soc. 2024 Jan; 27(1):e26206. Raizes E, Blandford J, McCune JM, Dybul M. PMID: 38193636; PMCID: PMC10775627.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence. Nat Commun. 2023 10 02; 14(1):6145. Reeves DB, Bacchus-Souffan C, Fitch M, Abdel-Mohsen M, Hoh R, Ahn H, Stone M, Hecht F, Martin J, Deeks SG, Hellerstein MK, McCune JM, Schiffer JT, Hunt PW. PMID: 37783718; PMCID: PMC10545742.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Recent Advances Using Genetic Therapies Against Infectious Diseases and for Vaccination. Hum Gene Ther. 2023 09; 34(17-18):896-904. Galy A, Berkhout B, Breckpot K, Pichon C, Bloom K, Kiem HP, Mühlebach MD, McCune JM. PMID: 37639360.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    6. Human fetal T cells: Insights into developmental specialization and mechanisms of lineage transition. Immunol Rev. 2023 05; 315(1):126-153. Burt TD, McCune JM. PMID: 36960621.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health. JCI Insight. 2022 03 08; 7(5). Swainson LA, Sharma AA, Ghneim K, Ribeiro SP, Wilkinson P, Dunham RM, Albright RG, Wong S, Estes JD, Piatak M, Deeks SG, Hunt PW, Sekaly RP, McCune JM. PMID: 35104248; PMCID: PMC8983135.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    8. HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives. mBio. 2021 10 26; 12(5):e0244721. Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, Palmer S. PMID: 34544282; PMCID: PMC8546577.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    9. Collaborative science to advance gene therapies in resource-limited parts of the world. Mol Ther. 2021 11 03; 29(11):3101-3102. McCune JM, Stevenson SC, Doehle BP, Trenor CC, Turner EH, Spector JM. PMID: 34464598; PMCID: PMC8571166.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    10. TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. JCI Insight. 2021 02 08; 6(3). Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin C, Matus-Nicodemos R, Hoh R, Krone M, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek DC, Brenchley JM, Sékaly RP, Pillai SK, Marson A, Deeks SG, McCune JM, Hunt PW. PMID: 33351785; PMCID: PMC7934879.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    11. Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART. PLoS Pathog. 2021 01; 17(1):e1009214. Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, Schiffer JT, Lewin SR, Hellerstein MK, McCune JM, Hunt PW. PMID: 33465157; PMCID: PMC7846027.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    12. Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells. Cell Rep. 2021 01 05; 34(1):108573. Bunis DG, Bronevetsky Y, Krow-Lucal E, Bhakta NR, Kim CC, Nerella S, Jones N, Mendoza VF, Bryson YJ, Gern JE, Rutishauser RL, Ye CJ, Sirota M, McCune JM, Burt TD. PMID: 33406429; PMCID: PMC10263444.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    13. CD57+ Memory T Cells Proliferate In Vivo. Cell Rep. 2020 12 15; 33(11):108501. Ahmed R, Miners KL, Lahoz-Beneytez J, Jones RE, Roger L, Baboonian C, Zhang Y, Wang ECY, Hellerstein MK, McCune JM, Baird DM, Price DA, Macallan DC, Asquith B, Ladell K. PMID: 33326780; PMCID: PMC7758161.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    14. Multi-stakeholder consensus on a target product profile for an HIV cure. Lancet HIV. 2021 01; 8(1):e42-e50. Lewin SR, Attoye T, Bansbach C, Doehle B, Dubé K, Dybul M, SenGupta D, Jiang A, Johnston R, Lamplough R, McCune JM, Nabel GJ, Ndung'u T, Pottage J, Ripin D, Rooney JF, Sikazwe I, Nsubuga M, Warren M, Deeks SG, Sunnylands 2019 Working Group. PMID: 33271125; PMCID: PMC7773628.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCellsPHPublic Health
    15. The case for an HIV cure and how to get there. Lancet HIV. 2021 01; 8(1):e51-e58. Dybul M, Attoye T, Baptiste S, Cherutich P, Dabis F, Deeks SG, Dieffenbach C, Doehle B, Goodenow MM, Jiang A, Kemps D, Lewin SR, Lumpkin MM, Mathae L, McCune JM, Ndung'u T, Nsubuga M, Peay HL, Pottage J, Warren M, Sikazwe I, Sunnylands 2019 Working Group. PMID: 33271124; PMCID: PMC7773626.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    16. Bringing Gene Therapies for HIV Disease to Resource-Limited Parts of the World. Hum Gene Ther. 2021 01; 32(1-2):21-30. McCune JM, Turner EH, Jiang A, Doehle BP. PMID: 32998595; PMCID: PMC10112459.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    17. Performance of the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus in early disease, across sexes and ethnicities. Ann Rheum Dis. 2020 10; 79(10):1333-1339. Johnson SR, Brinks R, Costenbader KH, Daikh D, Mosca M, Ramsey-Goldman R, Smolen JS, Wofsy D, Boumpas DT, Kamen DL, Jayne D, Cervera R, Costedoat-Chalumeau N, Diamond B, Gladman DD, Hahn B, Hiepe F, Jacobsen S, Khanna D, Lerstrøm K, Massarotti E, McCune J, Ruiz-Irastorza G, Sanchez-Guerrero J, Schneider M, Urowitz M, Bertsias G, Hoyer BF, Leuchten N, Tani C, Tedeschi SK, Touma Z, Schmajuk G, Anic B, Assan F, Chan TM, Clarke AE, Crow MK, Czirják L, Doria A, Graninger WB, Halda-Kiss B, Hasni S, Izmirly PM, Jung M, Kumánovics G, Mariette X, Padjen I, Pego-Reigosa JM, Romero-Diaz J, Rúa-Figueroa Í, Seror R, Stummvoll GH, Tanaka Y, Tektonidou MG, Vasconcelos C, Vital EM, Wallace DJ, Yavuz S, Meroni PL, Fritzler MJ, Naden R, Dörner T, Aringer M. PMID: 32816709.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    18. Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection. Cell Rep. 2020 04 14; 31(2):107494. Cham LB, Torrez Dulgeroff LB, Tal MC, Adomati T, Li F, Bhat H, Huang A, Lang PA, Moreno ME, Rivera JM, Galkina SA, Kosikova G, Stoddart CA, McCune JM, Myers LM, Weissman IL, Lang KS, Hasenkrug KJ. PMID: 32294445; PMCID: PMC8369894.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    19. Why and where an HIV cure is needed and how it might be achieved. Nature. 2019 12; 576(7787):397-405. Ndung'u T, McCune JM, Deeks SG. PMID: 31853080; PMCID: PMC8052635.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    20. The Ban on US Government Funding Research Using Human Fetal Tissues: How Does This Fit with the NIH Mission to Advance Medical Science for the Benefit of the Citizenry? Stem Cell Reports. 2019 11 12; 13(5):777-786. McCune JM, Weissman IL. PMID: 31722191; PMCID: PMC6895704.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    21. Some Aspects of CD8+ T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):211-219. Deguit CDT, Hough M, Hoh R, Krone M, Pilcher CD, Martin JN, Deeks SG, McCune JM, Hunt PW, Rutishauser RL. PMID: 31513075; PMCID: PMC6746248.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    22. 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus. Arthritis Rheumatol. 2019 09; 71(9):1400-1412. Aringer M, Costenbader K, Daikh D, Brinks R, Mosca M, Ramsey-Goldman R, Smolen JS, Wofsy D, Boumpas DT, Kamen DL, Jayne D, Cervera R, Costedoat-Chalumeau N, Diamond B, Gladman DD, Hahn B, Hiepe F, Jacobsen S, Khanna D, Lerstrøm K, Massarotti E, McCune J, Ruiz-Irastorza G, Sanchez-Guerrero J, Schneider M, Urowitz M, Bertsias G, Hoyer BF, Leuchten N, Tani C, Tedeschi SK, Touma Z, Schmajuk G, Anic B, Assan F, Chan TM, Clarke AE, Crow MK, Czirják L, Doria A, Graninger W, Halda-Kiss B, Hasni S, Izmirly PM, Jung M, Kumánovics G, Mariette X, Padjen I, Pego-Reigosa JM, Romero-Diaz J, Rúa-Figueroa Fernández Í, Seror R, Stummvoll GH, Tanaka Y, Tektonidou MG, Vasconcelos C, Vital EM, Wallace DJ, Yavuz S, Meroni PL, Fritzler MJ, Naden R, Dörner T, Johnson SR. PMID: 31385462; PMCID: PMC6827566.
      View in: PubMed   Mentions: 512     Fields:    Translation:Humans
    23. 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus. Ann Rheum Dis. 2019 09; 78(9):1151-1159. Aringer M, Costenbader K, Daikh D, Brinks R, Mosca M, Ramsey-Goldman R, Smolen JS, Wofsy D, Boumpas DT, Kamen DL, Jayne D, Cervera R, Costedoat-Chalumeau N, Diamond B, Gladman DD, Hahn B, Hiepe F, Jacobsen S, Khanna D, Lerstrøm K, Massarotti E, McCune J, Ruiz-Irastorza G, Sanchez-Guerrero J, Schneider M, Urowitz M, Bertsias G, Hoyer BF, Leuchten N, Tani C, Tedeschi SK, Touma Z, Schmajuk G, Anic B, Assan F, Chan TM, Clarke AE, Crow MK, Czirják L, Doria A, Graninger W, Halda-Kiss B, Hasni S, Izmirly PM, Jung M, Kumánovics G, Mariette X, Padjen I, Pego-Reigosa JM, Romero-Diaz J, Rúa-Figueroa Fernández Í, Seror R, Stummvoll GH, Tanaka Y, Tektonidou MG, Vasconcelos C, Vital EM, Wallace DJ, Yavuz S, Meroni PL, Fritzler MJ, Naden R, Dörner T, Johnson SR. PMID: 31383717.
      View in: PubMed   Mentions: 317     Fields:    Translation:Humans
    24. Kynurenine 3-Monooxygenase Inhibition during Acute Simian Immunodeficiency Virus Infection Lowers PD-1 Expression and Improves Post-Combination Antiretroviral Therapy CD4+ T Cell Counts and Body Weight. J Immunol. 2019 08 15; 203(4):899-910. Swainson LA, Ahn H, Pajanirassa P, Khetarpal V, Deleage C, Estes JD, Hunt PW, Munoz-Sanjuan I, McCune JM. PMID: 31285277; PMCID: PMC6684450.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    25. CD32-RNA Co-localizes with HIV-RNA in CD3+ Cells Found within Gut Tissues from Viremic and ART-Suppressed Individuals. Pathog Immun. 2019; 4(1):147-160. Vásquez JJ, Aguilar-Rodriguez BL, Rodriguez L, Hogan LE, Somsouk M, McCune JM, Deeks SG, Laszik ZG, Hunt PW, Henrich TJ. PMID: 31139759; PMCID: PMC6508427.
      View in: PubMed   Mentions: 8  
    26. HIV "cure": A shot in the arm? EBioMedicine. 2019 04; 42:3-5. Peluso MJ, Deeks SG, McCune JM. PMID: 30982768; PMCID: PMC6491910.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    27. Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans. Hum Mol Genet. 2018 11 01; 27(21):3813-3824. Hanscombe KB, Morris DL, Noble JA, Dilthey AT, Tombleson P, Kaufman KM, Comeau M, Langefeld CD, Alarcon-Riquelme ME, Gaffney PM, Jacob CO, Sivils KL, Tsao BP, Alarcon GS, Brown EE, Croker J, Edberg J, Gilkeson G, James JA, Kamen DL, Kelly JA, McCune J, Merrill JT, Petri M, Ramsey-Goldman R, Reveille JD, Salmon JE, Scofield H, Utset T, Wallace DJ, Weisman MH, Kimberly RP, Harley JB, Lewis CM, Criswell LA, Vyse TJ. PMID: 30085094; PMCID: PMC6196648.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    28. A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function. PLoS Pathog. 2018 03; 14(3):e1006806. Chitre AS, Kattah MG, Rosli YY, Pao M, Deswal M, Deeks SG, Hunt PW, Abdel-Mohsen M, Montaner LJ, Kim CC, Ma A, Somsouk M, McCune JM. PMID: 29505600; PMCID: PMC5854440.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    29. Elucidating the Burden of HIV in Tissues Using Multiplexed Immunofluorescence and In Situ Hybridization: Methods for the Single-Cell Phenotypic Characterization of Cells Harboring HIV In Situ. J Histochem Cytochem. 2018 06; 66(6):427-446. Vasquez JJ, Hussien R, Aguilar-Rodriguez B, Junger H, Dobi D, Henrich TJ, Thanh C, Gibson E, Hogan LE, McCune J, Hunt PW, Stoddart CA, Laszik ZG. PMID: 29462571; PMCID: PMC5977441.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    30. Glut1 Expression Level on Inflammatory Monocytes is Associated With Markers of Cardiovascular Disease Risk in HIV-Infected Individuals. J Acquir Immune Defic Syndr. 2018 02 01; 77(2):e28-e30. Anzinger JJ, Butterfield TR, Gouillou M, McCune JM, Crowe SM, Palmer CS. PMID: 28961681.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    31. Memory T Cell Proliferation before Hepatitis C Virus Therapy Predicts Antiviral Immune Responses and Treatment Success. J Immunol. 2018 02 01; 200(3):1124-1132. Méndez-Lagares G, Lu D, Chen C, Terrault N, Segal MR, Khalili M, Monto A, Shen H, Manos MM, Lanier LL, Ryan JC, McCune JM, Hartigan-O'Connor DJ. PMID: 29263212; PMCID: PMC5780234.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    32. HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study. PLoS Med. 2017 Nov; 14(11):e1002417. Henrich TJ, Hatano H, Bacon O, Hogan LE, Rutishauser R, Hill A, Kearney MF, Anderson EM, Buchbinder SP, Cohen SE, Abdel-Mohsen M, Pohlmeyer CW, Fromentin R, Hoh R, Liu AY, McCune JM, Spindler J, Metcalf-Pate K, Hobbs KS, Thanh C, Gibson EA, Kuritzkes DR, Siliciano RF, Price RW, Richman DD, Chomont N, Siliciano JD, Mellors JW, Yukl SA, Blankson JN, Liegler T, Deeks SG. PMID: 29112956; PMCID: PMC5675377.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCellsPHPublic Health
    33. IL-21 Therapy Controls Immune Activation and Maintains Antiviral CD8+ T Cell Responses in Acute Simian Immunodeficiency Virus Infection. AIDS Res Hum Retroviruses. 2017 Nov; 33(S1):S81-S92. Méndez-Lagares G, Lu D, Merriam D, Baker CA, Villinger F, Van Rompay KKA, McCune JM, Hartigan-O'Connor DJ. PMID: 29140110; PMCID: PMC5684667.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    34. Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection. FEBS Lett. 2017 10; 591(20):3319-3332. Palmer CS, Duette GA, Wagner MCE, Henstridge DC, Saleh S, Pereira C, Zhou J, Simar D, Lewin SR, Ostrowski M, McCune JM, Crowe SM. PMID: 28892135; PMCID: PMC5658250.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
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