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    Kanade Shinkai, MD, PhD

    TitleAssociate Professor
    SchoolUCSF School of Medicine
    DepartmentDermatology
    Phone415-353-7890
    vCardDownload vCard

      Collapse Biography 
      Collapse Education and Training
      University of California, San FranciscoM.D. Medicine2004
      University of California, San FranciscoPh.D. Graduate Division (TETRAD Program)2004

      Collapse Overview 
      Collapse Overview
      I am a dermatologist who specializes in medical dermatology, seeing patients in both the inpatient and outpatient settings. I am passionate about providing each and every one of my patients with the most evidence-based medical treatments for their cutaneous disease, and to educate my patients to promote their best health of their skin. As an academic physician, I strive to advance the collective knowledge of medical information in the field of dermatology through research and collaboration to better understand trends in cutaneous disease, dermatologic manifestations of systemic disease, and the quality of life of patients who live with skin conditions. I am also passionate about teaching others about dermatology, including practicing dermatologists, the next generation of dermatologists, and other medical specialists who encounter skin disease in their clinical practice. I have been part of the UCSF community since 1995.

      I believe that medical education is a mandate and privilege of being an academic physician. Highlights of my work in medical education at UCSF and beyond include:
      • Associate Residency Program Director, UCSF Department of Dermatology (2011 - present)
      • Director, Clinical Performance Exam, UCSF School of Medicine (2014 - present)
      • Competency Director, Patient Care, UCSF School of Medicine (2014 - present)
      • Mentor, Academic Dermatology Leadership Program, American Academy of Dermatology (2014 - present)
      • Director, Medical Student electives in dermatology, UCSF School of Medicine (2009 - 2014)
      • Director, Clinical Skills Guidance/ Remediation Program, UCSF School of Medicine (2012 - 2014)
      • Invited speaker, workshop facilitator in communications coaching. I am a certified mediator (conflict resolution expert) who serves as a volunteer mediator for the UCSF community and one of my educational interests is in communications coaching, to help health professionals communicate more effectively and richly with their colleagues and patients alike. I have facilitated, co-facilitated, and developed curricula in communication and conflict resolution, including a workshop entitled "Taking the difficult out of difficult conversations."

      My current clinical roles as an attending physician at UCSF include:
      • UCSF Department of Dermatology, Acne Specialty Clinic
      • UCSF Multidisciplinary Clinic for Polycystic Ovary Syndrome (PCOS)
      • UCSF Department of Dermatology, Faculty practice
      • UCSF inpatient consultative dermatology service
      • UCSF Department of Dermatology, Complex Medical Dermatology Resident Continuity Clinic (teaching preceptor)


      Collapse ORNG Applications 
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      Collapse Clinical Trials

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Quinn MM, Kao CN, Ahmad A, Lenhart N, Shinkai K, Cedars MI, Huddleston HG. Raising threshold for diagnosis of polycystic ovary syndrome excludes population of patients with metabolic risk. Fertil Steril. 2016 Oct; 106(5):1244-1251. PMID: 27445197.
        View in: PubMed
      2. Pasch L, He SY, Huddleston H, Cedars MI, Beshay A, Zane LT, Shinkai K. Clinician vs Self-ratings of Hirsutism in Patients With Polycystic Ovarian Syndrome: Associations With Quality of Life and Depression. JAMA Dermatol. 2016 Jul 1; 152(7):783-8. PMID: 26942548.
        View in: PubMed
      3. Dizon MP, Schmidt TH, Shinkai K. High-value, cost-conscious evaluation for PCOS: which tests should be routinely ordered in acne patients? Cutis. 2016 Jul; 98(1):11-3. PMID: 27529705.
        View in: PubMed
      4. Chen YC, Rosenblum MD, Shinkai K. Plasmacytoid dendritic cells (pDCs) and regulatory T (Treg) cells may be the key to viral reactivation in drug-induced hypersensitivity syndrome (DIHS). J Am Acad Dermatol. 2016 Jun; 74(6):1288-9. PMID: 27185444.
        View in: PubMed
      5. Kroshinsky D, Cotliar J, Hughey LC, Shinkai K, Fox LP. Association of Dermatology Consultation With Accuracy of Cutaneous Disorder Diagnoses in Hospitalized Patients: A Multicenter Analysis. JAMA Dermatol. 2016 Apr 1; 152(4):477-80. PMID: 26762199.
        View in: PubMed
      6. Schmidt TH, Khanijow K, Cedars MI, Huddleston H, Pasch L, Wang ET, Lee J, Zane LT, Shinkai K. Cutaneous Findings and Systemic Associations in Women With Polycystic Ovary Syndrome. JAMA Dermatol. 2016 Apr 1; 152(4):391-8. PMID: 26720591.
        View in: PubMed
      7. Beshay A, Liu M, Fox L, Shinkai K. Inpatient dermatology consultative programs: A continued need, tools for needs assessment for curriculum development, and a call for new methods of teaching. J Am Acad Dermatol. 2016 Apr; 74(4):769-71. PMID: 26979361.
        View in: PubMed
      8. Williams K, Shinkai K. Evaluation and management of the patient with multiple syringomas: A systematic review of the literature. J Am Acad Dermatol. 2016 Jun; 74(6):1234-1240.e9. PMID: 26850654.
        View in: PubMed
      9. Shinkai K, McMichael A, Linos E. Isotretinoin Laboratory Test Monitoring-A Call to Decrease Testing in an Era of High-Value, Cost-Conscious Care. JAMA Dermatol. 2016 Jan 1; 152(1):17-9. PMID: 26629966.
        View in: PubMed
      10. Ikediobi O, Chen YC, Shinkai K. Familial secondary hyperhidrosis associated with tumor necrosis factor-alpha inhibitor treatment. JAAD Case Rep. 2015 Nov; 1(6):418-20. PMID: 27051797.
        View in: PubMed
      11. Greenwood EA, Noel MW, Kao CN, Shinkai K, Pasch LA, Cedars MI, Huddleston HG. Vigorous exercise is associated with superior metabolic profiles in polycystic ovary syndrome independent of total exercise expenditure. Fertil Steril. 2016 Feb; 105(2):486-93. PMID: 26551442.
        View in: PubMed
      12. Canavan TN, Mathes EF, Frieden IJ, Shinkai K. Reply to: "Diagnosing Mycoplasma pneumoniae-induced rash and mucositis (MIRM) in the emergency room". J Am Acad Dermatol. 2015 Aug; 73(2):e69. PMID: 26184003.
        View in: PubMed
      13. Strazzula L, Cotliar J, Fox LP, Hughey L, Shinkai K, Gee SN, Kroshinsky D. Inpatient dermatology consultation aids diagnosis of cellulitis among hospitalized patients: A multi-institutional analysis. J Am Acad Dermatol. 2015 Jul; 73(1):70-5. PMID: 26089048.
        View in: PubMed
      14. Schmidt TH, Shinkai K. Evidence-based approach to cutaneous hyperandrogenism in women. J Am Acad Dermatol. 2015 Oct; 73(4):672-90. PMID: 26138647.
        View in: PubMed
      15. Greenwood EA, Pasch LA, Shinkai K, Cedars MI, Huddleston HG. Putative role for insulin resistance in depression risk in polycystic ovary syndrome. Fertil Steril. 2015 Sep; 104(3):707-14.e1. PMID: 26054555.
        View in: PubMed
      16. Sun NZ, Brezinski EA, Berliner J, Haemel A, Connolly MK, Gensler L, McCalmont TH, Shinkai K. Updates in adult-onset Still disease: Atypical cutaneous manifestations and associations with delayed malignancy. J Am Acad Dermatol. 2015 Aug; 73(2):294-303. PMID: 26054431.
        View in: PubMed
      17. Kamangar F, Okhovat JP, Schmidt T, Beshay A, Pasch L, Cedars MI, Huddleston H, Shinkai K. Polycystic Ovary Syndrome: Special Diagnostic and Therapeutic Considerations for Children. Pediatr Dermatol. 2015 Sep-Oct; 32(5):571-8. PMID: 25787290.
        View in: PubMed
      18. Canavan TN, Mathes EF, Frieden I, Shinkai K. Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review. J Am Acad Dermatol. 2015 Feb; 72(2):239-45. PMID: 25592340.
        View in: PubMed
      19. Okhovat JP, Shinkai K. Pyoderma gangrenosum. JAMA Dermatol. 2014 Sep; 150(9):1032. PMID: 25207536.
        View in: PubMed
      20. Liu M, Shinkai K. Reversible aquagenic pruritus associated with testosterone-induced erythrocytosis. J Am Acad Dermatol. 2014 Jun; 70(6):e139-40. PMID: 24831338.
        View in: PubMed
      21. Williams K, Tuttleton Arron S, Shinkai K. Skin nodule on the ear of a kidney-pancreas transplant recipient. Am J Transplant. 2014 May; 14(5):1217-9. PMID: 24751135.
        View in: PubMed
      22. Harp JL, Kinnebrew MA, Shinkai K. Severe cutaneous adverse reactions: impact of immunology, genetics, and pharmacology. Semin Cutan Med Surg. 2014 Mar; 33(1):17-27. PMID: 25037255.
        View in: PubMed
      23. Fox L, Shinkai K. Introduction. Semin Cutan Med Surg. 2014 Mar; 33(1):1. PMID: 25037252.
        View in: PubMed
      24. Liao W, Cordoro K, Frieden I, Shinkai K. How to prepare and deliver a great talk. Clin Dermatol. 2014 Nov-Dec; 32(6):878-82. PMID: 25441479.
        View in: PubMed
      25. Quinn M, Shinkai K, Pasch L, Kuzmich L, Cedars M, Huddleston H. Prevalence of androgenic alopecia in patients with polycystic ovary syndrome and characterization of associated clinical and biochemical features. Fertil Steril. 2014 Apr; 101(4):1129-34. PMID: 24534277.
        View in: PubMed
      26. Schulman JM, Yoon C, Schwarz J, Vagefi PA, Mully TW, Shinkai K. Absence of peripheral blood chimerism in graft-vs-host disease following orthotopic liver transplantation: case report and review of the literature. Int J Dermatol. 2014 Nov; 53(11):e492-8. PMID: 24372059; PMCID: PMC4441623.
      27. Kanada KN, Schwartz BS, Pincus LB, Berger TG, Jacobs RA, Shinkai K. A therapeutic trial of antituberculous therapy for suspected lupus vulgaris: How long does it take to see clinical improvement? J Am Acad Dermatol. 2013 Nov; 69(5):e252-4. PMID: 24124850.
        View in: PubMed
      28. Gogia R, Grekin RC, Shinkai K. Eruptive self-resolving keratoacanthomas developing after treatment with photodynamic therapy and microdermabrasion. Dermatol Surg. 2013 Nov; 39(11):1717-20. PMID: 24118143.
        View in: PubMed
      29. Pugashetti R, Shinkai K. Treatment of acne vulgaris in pregnant patients. Dermatol Ther. 2013 Jul-Aug; 26(4):302-11. PMID: 23914887.
        View in: PubMed
      30. Cipriano SD, Dybbro E, Boscardin CK, Shinkai K, Berger TG. Online learning in a dermatology clerkship: piloting the new American Academy of Dermatology Medical Student Core Curriculum. J Am Acad Dermatol. 2013 Aug; 69(2):267-72. PMID: 23683728.
        View in: PubMed
      31. Butler D, Shinkai K. What do autoinflammatory syndromes teach about common cutaneous diseases such as pyoderma gangrenosum? A commentary. Dermatol Clin. 2013 Jul; 31(3):427-35. PMID: 23827245.
        View in: PubMed
      32. Wang ET, Kao CN, Shinkai K, Pasch L, Cedars MI, Huddleston HG. Phenotypic comparison of Caucasian and Asian women with polycystic ovary syndrome: a cross-sectional study. Fertil Steril. 2013 Jul; 100(1):214-8. PMID: 23557763.
        View in: PubMed
      33. Coggshall K, Farsani T, Ruben B, McCalmont TH, Berger TG, Fox LP, Shinkai K. Keratitis, ichthyosis, and deafness syndrome: a review of infectious and neoplastic complications. J Am Acad Dermatol. 2013 Jul; 69(1):127-34. PMID: 23384797.
        View in: PubMed
      34. Hobeika M, Pollitt R, Freise C, Shinkai K. Fever and rash one month after orthotopic liver transplantation. Am J Transplant. 2013 Jan; 13(1):236-8; quiz 238. PMID: 23279683.
        View in: PubMed
      35. Scharschmidt TC, Amerson EH, Rosenberg OS, Jacobs RA, McCalmont TH, Shinkai K. Immune reconstitution reactions in human immunodeficiency virus-negative patients: report of a case and review of the literature. JAMA Dermatol. 2013 Jan; 149(1):74-8. PMID: 23324760; PMCID: PMC3773570.
      36. Kamangar F, Shinkai K. Acne in the adult female patient: a practical approach. Int J Dermatol. 2012 Oct; 51(10):1162-74. PMID: 22994662.
        View in: PubMed
      37. Hansra NK, Shinkai K, Fox LP. Ethical issues in inpatient consultative dermatology. Clin Dermatol. 2012 Sep-Oct; 30(5):496-500. PMID: 22902220.
        View in: PubMed
      38. Kamangar F, McCalmont T, Shinkai K. Cutaneous metastasis of thyroid carcinoma mimicking Mondor disease. J Am Acad Dermatol. 2012 Aug; 67(2):e79-81. PMID: 22794824.
        View in: PubMed
      39. Ahronowitz I, Harp J, Shinkai K. Etiology and management of pyoderma gangrenosum: a comprehensive review. Am J Clin Dermatol. 2012 Jun 1; 13(3):191-211. PMID: 22356259.
        View in: PubMed
      40. Shinkai K, Fox LP. What is your diagnosis? Inflamed molluscum contagiosum as a manifestation of immune reconstitution inflammatory syndrome. Cutis. 2012 May; 89(5):212, 219-20. PMID: 22768431.
        View in: PubMed
      41. Schulman JM, McCalmont TH, Shinkai K. Fulminant dermatomyositis with flagellate erythema. J Drugs Dermatol. 2011 Aug; 10(8):902-4. PMID: 21818513.
        View in: PubMed
      42. Hansra NK, Shinkai K. Cutaneous community-acquired and hospital-acquired methicillin-resistant Staphylococcus aureus. Dermatol Ther. 2011 Mar-Apr; 24(2):263-72. PMID: 21410616.
        View in: PubMed
      43. Pugashetti R, Shinkai K, Ruben BS, Grossman ME, Maldonado J, Fox LP. Calcium may preferentially deposit in areas of elastic tissue damage. J Am Acad Dermatol. 2011 Feb; 64(2):296-301. PMID: 21112670.
        View in: PubMed
      44. Hsiao JL, Antaya RJ, Berger T, Maurer T, Shinkai K, Leslie KS. Hidradenitis suppurativa and concomitant pyoderma gangrenosum: a case series and literature review. Arch Dermatol. 2010 Nov; 146(11):1265-70. PMID: 21079064.
        View in: PubMed
      45. Fox LP, Cotliar J, Hughey L, Kroshinsky D, Shinkai K. Hospitalist dermatology. J Am Acad Dermatol. 2009 Jul; 61(1):153-4. PMID: 19539858.
        View in: PubMed
      46. Shoo BA, Shinkai K, McCalmont TH, Fox LP. Xanthogranulomas associated with hematologic malignancy in adulthood. J Am Acad Dermatol. 2008 Sep; 59(3):488-93. PMID: 18538449.
        View in: PubMed
      47. Shinkai K, McCalmont TH, Leslie KS. Cryopyrin-associated periodic syndromes and autoinflammation. Clin Exp Dermatol. 2008 Jan; 33(1):1-9. PMID: 17927785.
        View in: PubMed
      48. Han MM, Pang J, Shinkai K, Franc B, Hawkins R, Aparici CM. Calciphylaxis and bone scintigraphy: case report with histological confirmation and review of the literature. Ann Nucl Med. 2007 Jun; 21(4):235-8. PMID: 17581723.
        View in: PubMed
      49. Voehringer D, Reese TA, Huang X, Shinkai K, Locksley RM. Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. J Exp Med. 2006 Jun 12; 203(6):1435-46. PMID: 16702603; PMCID: PMC2118302.
      50. Shinkai K, Kilcline C, Connolly MK, Frieden IJ. The pyrin family of fever genes: unmasking genetic determinants of autoinflammatory disease. Arch Dermatol. 2005 Feb; 141(2):242-7. PMID: 15724021.
        View in: PubMed
      51. Kilcline C, Shinkai K, Bree A, Modica R, Von Scheven E, Frieden IJ. Neonatal-onset multisystem inflammatory disorder: the emerging role of pyrin genes in autoinflammatory diseases. Arch Dermatol. 2005 Feb; 141(2):248-53. PMID: 15724022.
        View in: PubMed
      52. Voehringer D, Shinkai K, Locksley RM. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity. 2004 Mar; 20(3):267-77. PMID: 15030771.
        View in: PubMed
      53. Shinkai K, Mohrs M, Locksley RM. Helper T cells regulate type-2 innate immunity in vivo. Nature. 2002 Dec 19-26; 420(6917):825-9. PMID: 12490951.
        View in: PubMed
      54. Baron JL, Gardiner L, Nishimura S, Shinkai K, Locksley R, Ganem D. Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection. Immunity. 2002 Apr; 16(4):583-94. PMID: 11970881.
        View in: PubMed
      55. Mohrs M, Blankespoor CM, Wang ZE, Loots GG, Afzal V, Hadeiba H, Shinkai K, Rubin EM, Locksley RM. Deletion of a coordinate regulator of type 2 cytokine expression in mice. Nat Immunol. 2001 Sep; 2(9):842-7. PMID: 11526400.
        View in: PubMed
      56. Mohrs M, Shinkai K, Mohrs K, Locksley RM. Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. Immunity. 2001 Aug; 15(2):303-11. PMID: 11520464.
        View in: PubMed
      57. Shinkai K, Locksley RM. CD1, tuberculosis, and the evolution of major histocompatibility complex molecules. J Exp Med. 2000 Mar 20; 191(6):907-14. PMID: 10727453; PMCID: PMC2193123.
      58. Fowell DJ, Shinkai K, Liao XC, Beebe AM, Coffman RL, Littman DR, Locksley RM. Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells. Immunity. 1999 Oct; 11(4):399-409. PMID: 10549622.
        View in: PubMed
      59. Shinkai K, Nakamura K, Tsutsui N, Kuninishi Y, Iwaki Y, Nishida H, Suzuki R, Vohr HW, Takahashi M, Takahashi K, Kamimura Y, Maki E. Mouse popliteal lymph node assay for assessment of allergic and autoimmunity-inducing potentials of low-molecular-weight drugs. J Toxicol Sci. 1999 May; 24(2):95-102. PMID: 10349611.
        View in: PubMed
      60. Aida T, Kimura T, Ishikawa N, Shinkai K. Evaluation of allergenic potential of low-molecular compounds by mouse popliteal lymph node assay. J Toxicol Sci. 1998 Dec; 23(5):425-32. PMID: 9922946.
        View in: PubMed
      61. Fowell DJ, Bix M, Shinkai K, Lacy D, Locksley RM. Disease susceptibility and development of the cytokine repertoire in the murine Leishmania major model. Eur Cytokine Netw. 1998 Sep; 9(3 Suppl):102-6. PMID: 9831197.
        View in: PubMed
      62. Locksley RM, Fowell DJ, Shinkai K, Wakil AE, Lacy D, Bix M. Development of CD4+ effector T cells and susceptibility to infectious diseases. Adv Exp Med Biol. 1998; 452:45-52. PMID: 9889958.
        View in: PubMed
      63. Isoai A, Giga-Hama Y, Shinkai K, Mukai M, Akedo H, Kumagai H. Tumor invasion-inhibiting factor 2: primary structure and inhibitory effect on invasion in vitro and pulmonary metastasis of tumor cells. Cancer Res. 1992 Mar 15; 52(6):1422-6. PMID: 1311631.
        View in: PubMed
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