William Ryan, MD

Title(s)Associate Professor, Otolaryngology
SchoolSchool of Medicine
Address550 16th St
San Francisco CA 94158
Phone415-502-1877
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityM.D.2005School of Medicine
    Collapse Awards and Honors
    Wesleyan University1997Phi Beta Kappa

    Collapse Overview 
    Collapse Overview
    Dr. William R. Ryan is a board-certified, fellowship-trained, head and neck oncologic surgeon and associate professor at the University of California-San Francisco (UCSF), Bakar Cancer Hospital / Helen Diller Comprehensive Cancer Center at Mission Bay in the Division of Head and Neck Oncologic and Endocrine Surgery in the Department of Otolaryngology-Head and Neck Surgery.

    Clinically, Dr. Ryan is skilled in caring for patients with benign and malignant tumors of the head and neck and salivary gland inflammatory disorders with the appropriate application of robotic, endoscopic, minimally invasive, and traditional surgical techniques. He regularly performs ultrasonography in clinic and in the operating room for his patients. He also has special expertise in transoral robotic surgery (TORS), sialendoscopy, sentinel lymph node biopsy, and regional reconstruction of the face, mouth, and neck. Dr. Ryan helps direct the Robotic Head and Neck Surgery Center, Thyroid Surgery Center, and Salivary Gland Surgery Center at UCSF.

    Dr. Ryan is committed to providing adequate information and being as accessible as possible to his patients.

    Dr. Ryan is actively involved in teaching and mentorship in the UCSF residency and fellowship training programs and the School of Medicine. He serves as the head and neck surgical oncology fellowship co-director. He also directs the year-long Prendergast clinical research fellowship for medical students.

    He is a regular invited lecturer and panelist nationally and at UCSF on various aspects of head and neck surgery, salivary duct surgery, and head and neck ultrasound. His research and education interests include functional quality of life outcomes after treatment of human papilloma virus associated (HPV+) oropharynx carcinoma, oral cavity cancer, and salivary tumors, the quality of life impact of sialendoscopic-assisted salivary duct surgery for chronic sialadenitis, surgeon-performed ultrasound applications for the management of salivary disease, the utility of imaging surveillance for various head and neck cancers, and the role of surgery alone for the treatment of HPV+ oropharynx carcinoma. He is the principal investigator in a clinical trial testing the drug ruxolitinib on upper aerodigestive tract squamous cell carcinoma. He has authored over 70 published peer-reviewed journal articles and 4 book chapters. He serves on multiple committees within the American Head and Neck Society. He is a fellow of the Triological Society. He is a regular reviewer for the journals: Laryngoscope, Head and Neck, Otolaryngology-Head and Neck Surgery, JAMA-Otolaryngology-Head and Neck Surgery, and several others. He is a co-director for the following 2 annual courses: UCSF/Tripler Pacific Rim Otolaryngology-Head and Neck Surgery Update and the UCSF Sialendoscopy/Salivary Duct Surgery Update.

    Dr. Ryan earned his medical degree from Stanford University School of Medicine in 2005, where he also completed his residency in otolaryngology-head and neck surgery in 2010. Following his residency, he completed a fellowship in advanced head and neck oncologic and endocrine surgery at UCSF in 2011. He joined the UCSF faculty in 2011.

    Away from his career, he enjoys surfing, skiing, playing guitar, seeing music, hiking, healthy food, and time with his friends and family, especially his wife, daughter, and son.

    Specialty:
    Head and Neck Surgical Oncology, Salivary Gland and Duct Surgery and Sialendoscopy, Thyroid and Parathyroid Surgery

    Expertise:
    Head and Neck Surgical Oncology, Transoral Robotic Surgery, Surgeon-Performed Ultrasound, Salivary Gland and Duct Surgery and Sialendoscopy, Thyroid and Parathyroid Surgery

    Professional Interests:
    Head and Neck Tumors, transoral robotic surgery, surgeon-performed ultrasound, salivary surgery/sialoendoscopy, thyroid/parathyroid surgery, endoscopic sinus/skull base surgery, and facial reconstruction, outcomes research. salivary function in setting of oncologic treatments, head and neck surgery technique commonalities across the United States, the impact of sialendoscopy on patient symptoms, the benefits and drawbacks of head and neck cancer surveillance with radiology

    Education and Training:
    • Medical School: Stanford University, CA
    • Internship: Stanford University, CA – Head and Neck Surgery
    • Residency: Stanford University, CA – Otolaryngology-Head and Neck Surgery
    • Fellowship: University of California, San Francisco – Head and Neck Oncologic Surgery

    Awards and Honors:
    • 1997 Phi Beta Kappa, Wesleyan University
    • 2004, Best paper by a medical student award, 6th International Conference on Head and Neck Cancer, Washington D.C
    • 2009, Honorable Mention-Scientific Content Award, Stanford Otolaryngology Resident Research Symposium
    • 2011 University of California-San Francisco - Pinnacle Award- Highest Patient Satisfaction Award For A Clinical Division (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery)
    • 2012 University of California-San Francisco - Pinnacle Award - Highest Patient Satisfaction Award For A Clinical Division at UCSF (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery)
    • 2013 University of California-San Francisco - Pinnacle Award (Honorable Mention / 3rd Place) - Highest Patient Satisfaction Award For A Clinical Division at UCSF (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery)

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Impact of Smoking and Primary Tumor Subsite on Recurrence in HPV-Associated Oropharyngeal Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2021 Jun 29; 1945998211024515. Lee RH, Salesky M, Benjamin T, El-Sayed IH, George JR, Ha PK, Ryan WR, Heaton CM. PMID: 34182836.
      View in: PubMed   Mentions:    Fields:    
    2. Transoral Excision of Parapharyngeal Space Tumors. Otolaryngol Clin North Am. 2021 Jun; 54(3):531-541. Larson AR, Ryan WR. PMID: 34024481.
      View in: PubMed   Mentions:    Fields:    
    3. The Science and Art of Salivary Care. Otolaryngol Clin North Am. 2021 06; 54(3):xv-xvi. Gillespie MB, Ryan WR. PMID: 34024494.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. A prospective study of patient-reported xerostomia-related outcomes after parotidectomy. Laryngoscope Investig Otolaryngol. 2021 Aug; 6(4):683-689. Brodie KD, Zebolsky AL, Ochoa E, Ha PK, Heaton CM, El-Sayed IH, Ryan WR. PMID: 34401492.
      View in: PubMed   Mentions:
    5. Oncologic outcomes of human papillomavirus-associated oropharynx carcinoma treated with surgery alone: A 12-institution study of 344 patients. Cancer. 2021 Sep 01; 127(17):3092-3106. Ryan WR, Xu MJ, Ochoa E, Plonowska-Hirschfeld KA, Zebolsky AL, Ha PK, Bewley AF, Mallen-St Clair J, Joshi AS, Coffey CS, Faraji F, MacDonald BV, Houlton JJ, Gobillot TA, Curry JM, Philips R, Hackman TG, Richmon JD, Holcomb AJ, Coughlin AM, Panwar A, Smith RB, Herberg ME, Fakhry C, Cognetti DM. PMID: 33957701.
      View in: PubMed   Mentions:    Fields:    
    6. Botulinum toxin for chronic parotid sialadenitis: A case series and systematic review. Laryngoscope Investig Otolaryngol. 2021 Jun; 6(3):404-413. Strohl MP, Chang CF, Ryan WR, Chang JL. PMID: 34195360.
      View in: PubMed   Mentions:
    7. Impact of surgical margins on local control in patients undergoing single-modality transoral robotic surgery for HPV-related oropharyngeal squamous cell carcinoma. Head Neck. 2021 08; 43(8):2434-2444. Holcomb AJ, Herberg M, Strohl M, Ochoa E, Feng AL, Abt NB, Mokhtari TE, Suresh K, McHugh CI, Parikh AS, Sadow P, Faquin W, Faden D, Deschler DG, Varvares MA, Lin DT, Fakhry C, Ryan WR, Richmon JD. PMID: 33856083.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Patient-Reported Outcomes of Split-Thickness Skin Grafts for Floor of Mouth Cancer Reconstruction. ORL J Otorhinolaryngol Relat Spec. 2021; 83(3):151-158. Larson AR, Han M, Webb KL, Ochoa E, Stanford-Moore G, El-Sayed IH, George JR, Ha PK, Heaton CM, Ryan WR. PMID: 33582667.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Nasogastric tube feeding after transoral robotic surgery for oropharynx carcinoma. Am J Otolaryngol. 2021 May-Jun; 42(3):102857. Plonowska KA, Ochoa E, Zebolsky AL, Patel N, Hoppe KR, Ha PK, Heaton CM, Ryan WR. PMID: 33513477.
      View in: PubMed   Mentions:    Fields:    
    10. Predicting Adverse Histopathology and Need for Postsurgical Adjuvant Therapy for Human Papilloma Virus-Associated Oropharynx Carcinoma. Otolaryngol Head Neck Surg. 2021 08; 165(2):309-316. Ochoa E, Stanford-Moore G, Fakhry C, Ryan WR. PMID: 33399518.
      View in: PubMed   Mentions:    Fields:    
    11. Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva. Cell Rep. 2020 11 17; 33(7):108402. Saitou M, Gaylord EA, Xu E, May AJ, Neznanova L, Nathan S, Grawe A, Chang J, Ryan W, Ruhl S, Knox SM, Gokcumen O. PMID: 33207190.
      View in: PubMed   Mentions: 1     Fields:    
    12. Head and neck surgery during the coronavirus-19 pandemic: The University of California San Francisco experience. Head Neck. 2021 02; 43(2):622-629. Wai KC, Xu MJ, Lee RH, El-Sayed IH, George JR, Heaton CM, Knott PD, Park AM, Ryan WR, Seth R, Ha PK. PMID: 33098178.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Sialendoscopy in Chronic Obstructive Sialadenitis Without Sialolithiasis: A Prospective Cohort Study. Otolaryngol Head Neck Surg. 2021 03; 164(3):595-601. Plonowska KA, Ochoa E, Ryan WR, Chang JL. PMID: 32988282.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Patterns of Nodal Metastases and Predictors of Occult Disease in HPV-Associated Oropharynx Cancer. Otolaryngol Head Neck Surg. 2021 03; 164(3):624-630. Stanford-Moore GB, Ochoa E, Larson A, Han M, Hoppe K, Ryan WR. PMID: 32894979.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Salivary Gland Neoplasms. Current Otorhinolaryngology Reports. 2020 Sep 1; 8(3):298-303. Kane KA, Ryan RW, Cognetti CD. .
      View in: Publisher Site   Mentions:
    16. Salivary and lacrimal dysfunction after radioactive iodine for differentiated thyroid cancer: American Head and Neck Society Endocrine Surgery Section and Salivary Gland Section joint multidisciplinary clinical consensus statement of otolaryngology, ophthalmology, nuclear medicine and endocrinology. Head Neck. 2020 11; 42(11):3446-3459. Singer MC, Marchal F, Angelos P, Bernet V, Boucai L, Buchholzer S, Burkey B, Eisele D, Erkul E, Faure F, Freitag SK, Gillespie MB, Harrell RM, Hartl D, Haymart M, Leffert J, Mandel S, Miller BS, Morris J, Pearce EN, Rahmati R, Ryan WR, Schaitkin B, Schlumberger M, Stack BC, Van Nostrand D, Wong KK, Randolph G. PMID: 32812307.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Modified technique of submandibular gland transfer followed by intensity modulated radiotherapy to reduce xerostomia in head and neck cancer patients. Head Neck. 2020 09; 42(9):2340-2347. Chang CF, Ei-Sayed IH, George JR, Heaton CM, Ryan WR, Susko MS, Yom SS, Ha PK. PMID: 32400948.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Improved Tumor Control Related to Radiotherapy Technological Development for Hypopharyngeal Cancer. Laryngoscope. 2021 02; 131(2):E452-E458. Susko MS, Lazar AA, Dhar S, Chan JW, Shiao SL, Chapman CH, Johnson J, Quivey JM, Ryan WR, Heaton CM, Ha PK, Yom SS. PMID: 32396214.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Patient-Reported Quality of Life After Resection With Primary Closure for Oral Tongue Carcinoma. Laryngoscope. 2021 02; 131(2):312-318. Ochoa E, Larson AR, Han M, Webb KL, Stanford-Moore GB, El-Sayed IH, George JR, Ha PK, Heaton CM, Ryan WR. PMID: 32379355.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. HPV-positive Squamous Cell Carcinoma of the Larynx, Oral Cavity, and Hypopharynx: Clinicopathologic Characterization With Recognition of a Novel Warty Variant. Am J Surg Pathol. 2020 05; 44(5):691-702. Rooper LM, Windon MJ, Hernandez T, Miles B, Ha PK, Ryan WR, Van Zante A, Eisele DW, D'Souza G, Fakhry C, Westra WH. PMID: 31934915.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    21. Machine Learning for Predicting Complications in Head and Neck Microvascular Free Tissue Transfer. Laryngoscope. 2020 12; 130(12):E843-E849. Formeister EJ, Baum R, Knott PD, Seth R, Ha P, Ryan W, El-Sayed I, George J, Larson A, Plonowska K, Heaton C. PMID: 31990084.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Distinct biomarker and behavioral profiles of human papillomavirus-related oropharynx cancer patients by age. Oral Oncol. 2020 02; 101:104522. Fakhry C, Waterboer T, Westra WH, Rooper LM, Windon M, Troy T, Koch W, Gourin CG, Bender N, Yavvari S, Kiess AP, Miles BA, Ryan WR, Ha PK, Eisele DW, D'Souza G. PMID: 31881446.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    23. Predictors of Mortality in HPV-Associated Oropharynx Carcinoma Treated With Surgery Alone. Laryngoscope. 2020 07; 130(7):E423-E435. Han M, Stanford-Moore GB, Larson AR, Schoppy DW, Cognetti DM, Joshi AS, Houlton JJ, Ryan WR. PMID: 31675132.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    24. Beyond Depth of Invasion: Adverse Pathologic Tumor Features in Early Oral Tongue Squamous Cell Carcinoma. Laryngoscope. 2020 07; 130(7):1715-1720. Larson AR, Kemmer J, Formeister E, El-Sayed I, Ha P, George J, Ryan W, Chan E, Heaton C. PMID: 31411752.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    25. Patterns of care and survival impact of adjuvant chemoradiotherapy for oropharyngeal cancer with intermediate-risk features. Head Neck. 2019 09; 41(9):3177-3186. Goel AN, Sangar S, Mukdad L, Heaton CM, Ryan WR, Wang MB, Long JL, St John MA. PMID: 31107584.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Treatment modality impact on quality of life for human papillomavirus-associated oropharynx cancer. Laryngoscope. 2020 02; 130(2):E48-E56. Xu MJ, Plonowska KA, Gurman ZR, Humphrey AK, Ha PK, Wang SJ, El-Sayed IH, Heaton CM, George JR, Yom SS, Algazi AP, Ryan WR. PMID: 30919470.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Sex differences in HPV immunity among adults without cancer. Hum Vaccin Immunother. 2019; 15(7-8):1935-1941. Windon MJ, Waterboer T, Hillel AT, Chien W, Best S, Stewart C, Akst L, Troy T, Bender N, Miles B, Ryan WR, Mandal R, Pitman K, Eisele DW, Fakhry C, D'Souza G. PMID: 30650013.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    28. Socioeconomic disparities in a population of patients undergoing total thyroidectomy for benign disease. Head Neck. 2019 03; 41(3):715-721. Wu TJ, Ha PK, El-Sayed IH, George JR, Heaton CM, Ryan WR, Russell MD. PMID: 30521675.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Human Papillomavirus-Associated Oropharyngeal Cancer: Patterns of Nodal Disease. Otolaryngol Head Neck Surg. 2019 03; 160(3):502-509. Plonowska KA, Strohl MP, Wang SJ, Ha PK, George JR, Heaton CM, El-Sayed IH, Mallen-St Clair J, Ryan WR. PMID: 30274544.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Advanced head and neck surgical techniques: A survey of US otolaryngology resident perspectives. Auris Nasus Larynx. 2019 Apr; 46(2):272-278. Plonowska KA, Ha PK, Ryan WR. PMID: 30170906.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. One-Year symptom outcomes after sialolithiasis treatment with sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2019 02; 129(2):396-402. Ryan WR, Plonowska KA, Gurman ZR, Aubin-Pouliot A, Chang JL. PMID: 30151855.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. One-year outcomes of sialendoscopic-assisted salivary duct surgery for sialadenitis without sialolithiasis. Laryngoscope. 2019 04; 129(4):890-896. Plonowska KA, Gurman ZR, Humphrey A, Chang JL, Ryan WR. PMID: 30152080.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments. Nat Med. 2018 08; 24(8):1178-1191. Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, Asthana S, Chan V, Krummel MF. PMID: 29942093.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansCells
    34. Shorter interval between radiation therapy and salvage laryngopharyngeal surgery increases complication rates following microvascular free tissue transfer. Am J Otolaryngol. 2018 Sep - Oct; 39(5):548-552. Formeister EJ, Sean Alemi A, El-Sayed I, George JR, Ha P, Daniel Knott P, Ryan WR, Seth R, Tamplen ML, Heaton CM. PMID: 29908709.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Human Papillomavirus in the Mouth and Throat: More Widespread Than Expected? JAMA Otolaryngol Head Neck Surg. 2018 06 01; 144(6):525-526. Ryan WR, Plonowska K. PMID: 29800955.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    36. Undifferentiated pleomorphic sarcoma: Factors predictive of adverse outcomes. J Am Acad Dermatol. 2018 Nov; 79(5):853-859. Winchester D, Lehman J, Tello T, Chimato N, Hocker T, Kim S, Chang J, Markey J, Yom SS, Ryan W, Mully T, Hodge D, Otley C, Arron ST. PMID: 29787841.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    37. Squamous Cell Carcinoma of the Soft Palate in the United States: A Population-Based Study. Otolaryngol Head Neck Surg. 2018 10; 159(4):662-668. Chan CK, Han AY, Alonso JE, Xu MJ, Mallen-St Clair J, Heaton CM, Ryan WR, Kuan EC, St John MA. PMID: 29734872.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    38. Increasing prevalence of human papillomavirus-positive oropharyngeal cancers among older adults. Cancer. 2018 07 15; 124(14):2993-2999. Windon MJ, D'Souza G, Rettig EM, Westra WH, van Zante A, Wang SJ, Ryan WR, Mydlarz WK, Ha PK, Miles BA, Koch W, Gourin C, Eisele DW, Fakhry C. PMID: 29710393.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    39. Mortality risk after clinical management of recurrent and metastatic adenoid cystic carcinoma. J Otolaryngol Head Neck Surg. 2018 Apr 25; 47(1):28. Xu MJ, Wu TJ, van Zante A, El-Sayed IH, Algazi AP, Ryan WR, Ha PK, Yom SS. PMID: 29695289.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    40. Surgeon-performed ultrasound for the assessment of parotid masses. Am J Otolaryngol. 2018 Sep - Oct; 39(5):467-471. Zheng M, Plonowska KA, Strohl MP, Ryan WR. PMID: 29778636.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. Prognostic factors for human papillomavirus-positive and negative oropharyngeal carcinomas. Laryngoscope. 2018 08; 128(8):E287-E295. Yin LX, D'Souza G, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig EM, Ryan WR, Ha PK, Wentz A, Koch W, Eisele DW, Fakhry C. PMID: 29536542.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    42. CD29 is highly expressed on epithelial, myoepithelial, and mesenchymal stromal cells of human salivary glands. Oral Dis. 2018 May; 24(4):561-572. Togarrati PP, Dinglasan N, Desai S, Ryan WR, Muench MO. PMID: 29197149.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    43. Major prognostic factors for recurrence and survival independent of the American Joint Committee on Cancer eighth edition staging system in patients with cutaneous squamous cell carcinoma treated with multimodality therapy. Head Neck. 2018 07; 40(7):1406-1414. Xu MJ, Lazar AA, Garsa AA, Arron ST, Ryan WR, El-Sayed IH, George JR, Algazi AP, Heaton CM, Ha PK, Yom SS. PMID: 29524273.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med. 2018 03; 10(3). Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM. PMID: 29335337.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    45. High-Yield Purification, Preservation, and Serial Transplantation of Human Satellite Cells. Stem Cell Reports. 2018 03 13; 10(3):1160-1174. Garcia SM, Tamaki S, Lee S, Wong A, Jose A, Dreux J, Kouklis G, Sbitany H, Seth R, Knott PD, Heaton C, Ryan WR, Kim EA, Hansen SL, Hoffman WY, Pomerantz JH. PMID: 29478895.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    46. The survival impact of surgical therapy in squamous cell carcinoma of the hard palate. Laryngoscope. 2018 09; 128(9):2050-2055. Alonso JE, Han AY, Kuan EC, Strohl M, Clair JM, St John MA, Ryan WR, Heaton CM. PMID: 29399797.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    47. Salivary Fine Needle Aspiration Biopsy. Gland-Preserving Salivary Surgery. 2018 Jan 1; 27-37. Ryan RW, Sean Alemi SA, van Zante vA. .
      View in: Publisher Site   Mentions:
    48. Squamous cell carcinoma of unknown primary of the head and neck: Favorable prognostic factors comparable to those in oropharyngeal cancer. Head Neck. 2018 05; 40(5):904-916. Zhou MJ, van Zante A, Lazar AA, Groppo ER, Garsa AA, Ryan WR, El-Sayed IH, Eisele DW, Yom SS. PMID: 29210145.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    49. Comparison of Output Volume Thresholds for Drain Removal After Selective Lateral Neck Dissection: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2017 12 01; 143(12):1195-1199. Tamplen ML, Tamplen J, Shuman E, Heaton CM, George JR, Wang SJ, Ryan WR. PMID: 28837725.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. A Novel Approach to Oropharyngeal Foreign Body Removal. Otolaryngol Head Neck Surg. 2018 01; 158(1):194-196. Strohl MP, Dewyer NA, Sckolnick J, Ryan WR. PMID: 29039243.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. Prevalence of Highly Self-Directed Care Among Patients with HPV-Associated Oropharyngeal Cancer. International Journal of Radiation Oncology • Biology • Physics. 2017 Oct 1; 99(2):e327. Chapman CC, Ryan RW, Yom YS. .
      View in: Publisher Site   Mentions:
    52. Prognostic Factors for Recurrence and Survival Independent of the Revised AJCC 8th Edition Staging System in Patients with Cutaneous Squamous Cell Carcinoma Treated with Multimodality Therapy. International Journal of Radiation Oncology • Biology • Physics. 2017 Oct 1; 99(2):e383. Xu XM, Garsa GA, Lazar LA, Arron AS, Ryan RW, El-Sayed EI, George GJ, Algazi AA, Heaton HC, Ha HP, Yom YS. .
      View in: Publisher Site   Mentions:
    53. Surgeon-Performed Ultrasound for Chronic Obstructive Sialadenitis Helps Predict Sialendoscopic Findings and Outcomes. Otolaryngol Head Neck Surg. 2017 12; 157(6):973-980. Larson AR, Aubin-Pouliot A, Delagnes E, Zheng M, Chang JL, Ryan WR. PMID: 28871894.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. The COMMENCE trial: 2-year outcomes with an aortic bioprosthesis with RESILIA tissue. Eur J Cardiothorac Surg. 2017 Sep 01; 52(3):432-439. Puskas JD, Bavaria JE, Svensson LG, Blackstone EH, Griffith B, Gammie JS, Heimansohn DA, Sadowski J, Bartus K, Johnston DR, Rozanski J, Rosengart T, Girardi LN, Klodell CT, Mumtaz MA, Takayama H, Halkos M, Starnes V, Boateng P, Timek TA, Ryan W, Omer S, Smith CR, COMMENCE Trial Investigators . PMID: 28605428.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    55. Salivary duct stenosis: Short-term symptom outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 12; 127(12):2770-2776. Delagnes EA, Zheng M, Aubin-Pouliot A, Chang JL, Ryan WR. PMID: 28714528.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    56. Volumetric Growth Rate of Recurrent Pleomorphic Adenoma. Ann Otol Rhinol Laryngol. 2017 Jul; 126(7):544-547. Naunheim M, Wu X, Ryan WR, Wang SJ, Heaton CM. PMID: 28604082.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    57. Identification and characterization of a rich population of CD34+ mesenchymal stem/stromal cells in human parotid, sublingual and submandibular glands. Sci Rep. 2017 06 14; 7(1):3484. Togarrati PP, Sasaki RT, Abdel-Mohsen M, Dinglasan N, Deng X, Desai S, Emmerson E, Yee E, Ryan WR, da Silva MCP, Knox SM, Pillai SK, Muench MO. PMID: 28615711.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    58. (P069) Prognostic Factors for Recurrence and Survival Independent of the Revised AJCC 8th Edition Staging System in Patients With Cutaneous Squamous Cell Carcinoma. International Journal of Radiation Oncology • Biology • Physics. 2017 Jun 1; 98(2):e33-e34. Xu XM, Garsa GA, Lazar LA, Arron AS, Ryan RW, El-Sayed EI, Algazi AA, George GJ, Ha HP, Yom YS. .
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    59. (P060) Squamous Cell Carcinoma of Unknown Primary of the Head and Neck: “Low-Risk” Prognostic Factors for Disease Control and Survival Reminiscent of Oropharyngeal Cancers. International Journal of Radiation Oncology • Biology • Physics. 2017 Jun 1; 98(2):e31. Zhou ZM, Van Zante VA, Lazar LA, Groppo GE, Garsa GA, Ryan RW, El-Sayed EI, Eisele ED, Yom YS. .
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    60. The effect of submandibular gland preservation during level 1B neck dissection on postoperative xerostomia. Auris Nasus Larynx. 2018 Feb; 45(1):123-127. Markey JD, Morrel WG, Wang SJ, Ryan WR. PMID: 28449980.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    61. A feasibility and efficacy trial of a hand-held humidification device in patients undergoing radiotherapy for head and neck cancer. Support Care Cancer. 2017 08; 25(8):2611-2618. Ghosh P, Lazar AA, Ryan WR, Yom SS. PMID: 28353039.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. The prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer. Cancer. 2017 05 01; 123(9):1566-1575. Fakhry C, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig E, Yin LX, Ryan WR, Ha PK, Wentz A, Koch W, Richmon JD, Eisele DW, D'Souza G. PMID: 28241096.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    63. Differences in the Prevalence of Human Papillomavirus (HPV) in Head and Neck Squamous Cell Cancers by Sex, Race, Anatomic Tumor Site, and HPV Detection Method. JAMA Oncol. 2017 Feb 01; 3(2):169-177. D'Souza G, Westra WH, Wang SJ, van Zante A, Wentz A, Kluz N, Rettig E, Ryan WR, Ha PK, Kang H, Bishop J, Quon H, Kiess AP, Richmon JD, Eisele DW, Fakhry C. PMID: 27930766.
      View in: PubMed   Mentions: 37     Fields:    
    64. Does a Standalone Cancer Center Improve Head and Neck Microsurgical Outcomes? J Reconstr Microsurg. 2017 May; 33(4):252-256. Tamplen ML, Tamplen J, Torrecillas V, Seth R, Ricceri S, Hemmat S, Heaton C, Ryan WR, Knott PD. PMID: 28061519.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    65. Transoral robotic surgery (TORS) for excision of a retropharyngeal intramuscular lipoma. Auris Nasus Larynx. 2017 Dec; 44(6):742-744. Heaton CM, Ahmed SR, Ryan WR. PMID: 27956103.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    66. Chronic parotitis with multiple calcifications: Clinical and sialendoscopic findings. Laryngoscope. 2017 07; 127(7):1565-1570. Jáuregui E, Kiringoda R, Ryan WR, Eisele DW, Chang JL. PMID: 27861944.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    67. Earlier and more specific detection of persistent neck disease with diffusion-weighted MRI versus subsequent PET/CT after definitive chemoradiation for oropharyngeal squamous cell carcinoma. Head Neck. 2017 03; 39(3):432-438. Yu Y, Mabray M, Silveira W, Shen PY, Ryan WR, Uzelac A, Yom SS. PMID: 27726241.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    68. Sialadenitis without sialolithiasis: Prospective outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 05; 127(5):1073-1079. Delagnes EA, Aubin-Pouliot A, Zheng M, Chang JL, Ryan WR. PMID: 27701754.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    69. Volumetric Growth of Cervical Schwannoma as a Predictor of Surgical Intervention. Otolaryngol Head Neck Surg. 2017 01; 156(1):152-155. Alemi AS, Heaton CM, Ryan WR, El-Sayed I, Wang SJ. PMID: 27625027.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    70. Neck Dissection Technique Commonality and Variance: A Survey on Neck Dissection Technique Preferences among Head and Neck Oncologic Surgeons in the American Head and Neck Society. Int Arch Otorhinolaryngol. 2017 Jan; 21(1):8-16. Hemmat SM, Wang SJ, Ryan WR. PMID: 28050201.
      View in: PubMed   Mentions:
    71. Clinicopathologic characteristics and outcomes of recurrent oropharyngeal squamous cell carcinoma. Am J Otolaryngol. 2016 Nov - Dec; 37(6):513-516. Heaton CM, Yu K, Calkins S, George JR, Ryan WR, Wang SJ. PMID: 27522438.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    72. How, when, and from whom neck dissection operative technique is learned: An international survey on neck dissection education among head and neck oncologic surgeons. Am J Otolaryngol. 2016 Sep-Oct; 37(5):431-5. Hemmat S, Wang SJ, Ryan WR. PMID: 27221027.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    73. Benefits of Immediate Extubation Following Free Tissue Transfer for Head and Neck Reconstruction. J Reconstr Microsurg. 2016 Sep; 32(7):533-9. Tamplen ML, Ricceri S, Hemmat S, Seth R, Ryan WR, Knott PD. PMID: 27110906.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    74. Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer. J Otolaryngol Head Neck Surg. 2016 Mar 24; 45:20. Singer L, Calkins SM, Horvai AE, Ryan WR, Yom SS. PMID: 27009318.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    75. Sialendoscopy-assisted surgery and the chronic obstructive sialadenitis symptoms questionnaire: A prospective study. Laryngoscope. 2016 06; 126(6):1343-8. Aubin-Pouliot A, Delagnes EA, Chang JL, Ryan WR. PMID: 26972293.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    76. Early Detection of Persistent Neck Disease With Diffusion-Weighted MRI Following Chemoradiation for Squamous Cell Carcinomas of the Oropharynx. International Journal of Radiation Oncology • Biology • Physics. 2015 Nov 1; 93(3):e347. Yu YY, Mabray MM, Silveira SW, Shen SP, Ryan RW, Uzelac UA, Yom YS. .
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    77. Anterolateral Thigh Adipofascial Flap: A New Option for Scalp Reconstruction. J Reconstr Microsurg. 2016 Feb; 32(2):160-3. Markey JD, Seth R, Wang SJ, Ryan WR, El-Sayed IH, Knott PD. PMID: 26340759.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    78. Growth rate characteristics of Warthin's tumours of the parotid gland. Int J Oral Maxillofac Surg. 2015 Dec; 44(12):1474-9. Schwalje AT, Uzelac A, Ryan WR. PMID: 26314235.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    79. The Chronic Obstructive Sialadenitis Symptoms Questionnaire to assess sialendoscopy-assisted surgery. Laryngoscope. 2016 Jan; 126(1):93-9. Aubin-Pouliot A, Delagnes EA, Eisele DW, Chang JL, Ryan WR. PMID: 26256263.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    80. Prognostic significance of hyoid bone invasion in advanced base of tongue carcinoma treated by chemoradiation. Clin Otolaryngol. 2015 Jun; 40(3):260-5. Heaton CM, Al-Shwaiheen F, Liu CS, Yom SS, Ryan WR. PMID: 25641627.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    81. The Limitations of Routine Magnetic Resonance Imaging for Long-Term Post-Treatment Locoregional Surveillance of Salivary Carcinoma. ORL J Otorhinolaryngol Relat Spec. 2015; 77(3):132-40. Hemmat SM, Wang SJ, Uzelac A, Yom SS, Ryan WR. PMID: 26022374.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    82. Trans-oral robotic surgery and surgeon-performed trans-oral ultrasound for intraoperative location and excision of an isolated retropharyngeal lymph node metastasis of papillary thyroid carcinoma. Am J Otolaryngol. 2015 Sep-Oct; 36(5):710-4. Goepfert RP, Liu C, Ryan WR. PMID: 25964171.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    83. The advantages and drawbacks of routine magnetic resonance imaging for long-term post-treatment locoregional surveillance of oral cavity squamous cell carcinoma. Am J Otolaryngol. 2015 May-Jun; 36(3):415-23. Al-Shwaiheen FA, Wang SJ, Uzelac A, Yom SS, Ryan WR. PMID: 25697087.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    84. Development of a chemoradiation therapy toxicity staging system for oropharyngeal carcinoma. Laryngoscope. 2015 Apr; 125(4):869-76. Goepfert RP, Yom SS, Ryan WR, Cheung SW. PMID: 25388529.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    85. Elective lymphadenectomy during salvage for locally recurrent head and neck squamous cell carcinoma after radiation. Otolaryngol Head Neck Surg. 2014 Sep; 151(3):462-7. Prendes BL, Aubin-Pouliot A, Egbert N, Ryan WR. PMID: 24894423.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    86. Surgeon-performed ultrasound and transfacial sialoendoscopy for complete parotid duct stenosis. Laryngoscope. 2014 Feb; 124(2):418-20. Ryan WR, Chang JL, Eisele DW. PMID: 24130099.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    87. Prognostic Significance of Hyoid Bone Invasion in Advanced Base of Tongue Carcinoma Treated by Chemoradiation. Otolaryngology. 2013 Sep 1; 149(2_suppl):p187-p188. Heaton HC, Liu LC, Al-Shwaiheen AF, Ryan RW. .
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    88. Diffusion-Weighted Imaging Compared to 3-month PET/CT to Predict Response in the Irradiated Neck. International Journal of Radiation Oncology • Biology • Physics. 2012 Nov 1; 84(3):s475. Silveira SW, Shen SP, Tan TJ, Glastonbury GC, Quivey QJ, Ryan RW, Wang WS, Yom YS. .
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    89. Intraoperative tumor localization with surgeon-performed ultrasound-guided needle dye injection. Laryngoscope. 2011 Aug; 121(8):1651-5. Ryan WR, Orloff LA. PMID: 21660975.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    90. Correlations between symptoms, nasal endoscopy, and in-office computed tomography in post-surgical chronic rhinosinusitis patients. Laryngoscope. 2011 Mar; 121(3):674-8. Ryan WR, Ramachandra T, Hwang PH. PMID: 21305550.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    91. Safety of a preservative-free acidified saline nasal spray: a randomized, double-blind, placebo-controlled, crossover clinical trial. Arch Otolaryngol Head Neck Surg. 2010 Nov; 136(11):1099-103. Ryan WR, Hwang PH. PMID: 21079163.
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    92. A prospective evaluation of the efficacy of topical adhesive pads for the reduction of facial rhytids. Arch Facial Plast Surg. 2009 Jul-Aug; 11(4):252-6. Ryan WR, Most SP. PMID: 19620531.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    93. Long-term great auricular nerve morbidity after sacrifice during parotidectomy. Laryngoscope. 2009 Jun; 119(6):1140-6. Ryan WR, Fee WE. PMID: 19399835.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    94. Great auricular nerve morbidity after nerve sacrifice during parotidectomy. Arch Otolaryngol Head Neck Surg. 2006 Jun; 132(6):642-9. Ryan WR, Fee WE. PMID: 16785410.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    95. Positron-emission tomography for surveillance of head and neck cancer. Laryngoscope. 2005 Apr; 115(4):645-50. Ryan WR, Fee WE, Le QT, Pinto HA. PMID: 15805874.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    96. Crohn's disease patients who quit smoking have a reduced risk of reoperation for recurrence. Am J Surg. 2004 Feb; 187(2):219-25. Ryan WR, Allan RN, Yamamoto T, Keighley MR. PMID: 14769308.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansPHPublic Health
    97. Patients with Crohn's disease are unaware of the risks that smoking has on their disease. J Gastrointest Surg. 2003 Jul-Aug; 7(5):706-11. Ryan WR, Ley C, Allan RN, Keighley MR. PMID: 12850686.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    98. Patient satisfaction after carotid endarterectomy using a selective policy of local anesthesia. Am J Surg. 2000 May; 179(5):382-5. Quigley TM, Ryan WR, Morgan S. PMID: 10930485.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    99. Arthroscopic ankle fusion. Conn Med. 1997 Oct; 61(10):643-6. Fisher RL, Ryan WR, Dugdale TW, Zimmermann GA. PMID: 9375450.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    100. Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs). Bioorg Med Chem. 1997 Aug; 5(8):1591-600. Dutta AK, Ryan W, Thomas BF, Singer M, Compton DR, Martin BR, Razdan RK. PMID: 9313864.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    101. Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. J Pharmacol Exp Ther. 1995 Jun; 273(3):1172-81. Adams IB, Ryan W, Singer M, Thomas BF, Compton DR, Razdan RK, Martin BR. PMID: 7791088.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    102. A novel class of potent tetrahydrocannabinols (THCS): 2'-yne-delta 8- and delta 9-THCS. Life Sci. 1995; 56(23-24):2013-20. Ryan W, Singer M, Razdan RK, Compton DR, Martin BR. PMID: 7776826.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    103. Pharmacological and behavioral evaluation of alkylated anandamide analogs. Life Sci. 1995; 56(23-24):2041-8. Adams IB, Ryan W, Singer M, Razdan RK, Compton DR, Martin BR. PMID: 7776830.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    104. Characteristics of a two-site immunoradiometric assay for human skeletal alkaline phosphatase in serum. Clin Chem. 1994 May; 40(5):822-8. Panigrahi K, Delmas PD, Singer F, Ryan W, Reiss O, Fisher R, Miller PD, Mizrahi I, Darte C, Kress BC, et al. PMID: 8174258.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    105. Evaluation of factors affecting the performance of enzymatic SPan-1 immunoassays for pancreatic cancer. J Immunol Methods. 1989 Dec 20; 125(1-2):97-104. Ho JJ, Chung YS, Ryan W, Henslee JG, Kim YS. PMID: 2691579.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    106. Mucin-like antigens in a human pancreatic cancer cell line identified by murine monoclonal antibodies SPan-1 and YPan-1. Cancer Res. 1988 Jul 15; 48(14):3924-31. Ho JJ, Chung YS, Fujimoto Y, Bi N, Ryan W, Yuan SZ, Byrd JC, Kim YS. PMID: 2454732.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    107. Current status of laryngectomee rehabilitation: III. understanding of esophageal speech. Am J Otolaryngol. 1982 Mar-Apr; 3(2):91-6. Ryan W, Gates GA, Cantu E, Hearne EM. PMID: 7091545.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    108. Current status of laryngectomee rehabilitation: IV. attitudes about laryngectomee rehabilitation should change. Am J Otolaryngol. 1982 Mar-Apr; 3(2):97-103. Gates GA, Ryan W, Lauder E. PMID: 7091546.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    109. Current status of laryngectomee rehabilitation: II. Causes of failure. Am J Otolaryngol. 1982 Jan-Feb; 3(1):8-14. Gates GA, Ryan W, Cantu E, Hearne E. PMID: 7114393.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    110. Current status of laryngectomee rehabilitation: I. Results of therapy. Am J Otolaryngol. 1982 Jan-Feb; 3(1):1-7. Gates GA, Ryan W, Cooper JC, Lawlis GF, Cantu E, Hayashi T, Lauder E, Welch RW, Hearne E. PMID: 7114387.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    111. The post-thaw viability of red blood cells of ACD and CPD blood preserved in the frozen state with and without added adenine. Transfusion. 1972 May-Jun; 12(3):198-207. Gibson JG, Tullis JL, Tinch RJ, Ryan WR, DiForte S. PMID: 5026173.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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