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William Ryan, MD

Title(s)Associate Professor, Otolaryngology
SchoolSchool of Medicine
Phone415-502-1877
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityM.D.2005School of Medicine
    Collapse Awards and Honors
    Wesleyan University1997Phi Beta Kappa

    Collapse Overview 
    Collapse Overview
    Dr. William R. Ryan is a board-certified, fellowship-trained, head and neck oncologic surgeon and associate professor at the University of California-San Francisco (UCSF), Bakar Cancer Hospital / Helen Diller Comprehensive Cancer Center at Mission Bay in the Division of Head and Neck Oncologic and Endocrine Surgery in the Department of Otolaryngology-Head and Neck Surgery.

    Clinically, Dr. Ryan is skilled in caring for patients with benign and malignant tumors of the head and neck and salivary gland inflammatory disorders with the appropriate application of robotic, endoscopic, minimally invasive, and traditional surgical techniques. He regularly performs ultrasonography in clinic and in the operating room for his patients. He also has special expertise in transoral robotic surgery (TORS), sialendoscopy, sentinel lymph node biopsy, and regional reconstruction of the face, mouth, and neck. Dr. Ryan helps direct the Robotic Head and Neck Surgery Center, Thyroid Surgery Center, and Salivary Gland Surgery Center at UCSF.

    Dr. Ryan is committed to providing adequate information and being as accessible as possible to his patients.

    Dr. Ryan is actively involved in teaching and mentorship in the UCSF residency and fellowship training programs and the School of Medicine. He serves as the head and neck surgical oncology fellowship co-director. He also directs the year-long Prendergast clinical research fellowship for medical students.

    He is a regular invited lecturer and panelist nationally and at UCSF on various aspects of head and neck surgery, salivary duct surgery, and head and neck ultrasound. His research and education interests include functional quality of life outcomes after treatment of human papilloma virus associated (HPV+) oropharynx carcinoma, oral cavity cancer, and salivary tumors, the quality of life impact of sialendoscopic-assisted salivary duct surgery for chronic sialadenitis, surgeon-performed ultrasound applications for the management of salivary disease, the utility of imaging surveillance for various head and neck cancers, and the role of surgery alone for the treatment of HPV+ oropharynx carcinoma. He is the principal investigator in a clinical trial testing the drug ruxolitinib on upper aerodigestive tract squamous cell carcinoma. He has authored over 70 published peer-reviewed journal articles and 4 book chapters. He serves on multiple committees within the American Head and Neck Society. He is a fellow of the Triological Society. He is a regular reviewer for the journals: Laryngoscope, Head and Neck, Otolaryngology-Head and Neck Surgery, JAMA-Otolaryngology-Head and Neck Surgery, and several others. He is a co-director for the following 2 annual courses: UCSF/Tripler Pacific Rim Otolaryngology-Head and Neck Surgery Update and the UCSF Sialendoscopy/Salivary Duct Surgery Update.

    Dr. Ryan earned his medical degree from Stanford University School of Medicine in 2005, where he also completed his residency in otolaryngology-head and neck surgery in 2010. Following his residency, he completed a fellowship in advanced head and neck oncologic and endocrine surgery at UCSF in 2011. He joined the UCSF faculty in 2011.

    Away from his career, he enjoys surfing, skiing, playing guitar, seeing music, hiking, healthy food, and time with his friends and family, especially his wife, daughter, and son.

    Specialty:
    Head and Neck Surgical Oncology, Salivary Gland and Duct Surgery and Sialendoscopy, Thyroid and Parathyroid Surgery

    Expertise:
    Head and Neck Surgical Oncology, Transoral Robotic Surgery, Surgeon-Performed Ultrasound, Salivary Gland and Duct Surgery and Sialendoscopy, Thyroid and Parathyroid Surgery

    Professional Interests:
    Head and Neck Tumors, transoral robotic surgery, surgeon-performed ultrasound, salivary surgery/sialoendoscopy, thyroid/parathyroid surgery, endoscopic sinus/skull base surgery, and facial reconstruction, outcomes research. salivary function in setting of oncologic treatments, head and neck surgery technique commonalities across the United States, the impact of sialendoscopy on patient symptoms, the benefits and drawbacks of head and neck cancer surveillance with radiology

    Education and Training:
    • Medical School: Stanford University, CA
    • Internship: Stanford University, CA – Head and Neck Surgery
    • Residency: Stanford University, CA – Otolaryngology-Head and Neck Surgery
    • Fellowship: University of California, San Francisco – Head and Neck Oncologic Surgery

    Awards and Honors:
    • 1997 Phi Beta Kappa, Wesleyan University
    • 2004, Best paper by a medical student award, 6th International Conference on Head and Neck Cancer, Washington D.C
    • 2009, Honorable Mention-Scientific Content Award, Stanford Otolaryngology Resident Research Symposium
    • 2011 University of California-San Francisco - Pinnacle Award- Highest Patient Satisfaction Award For A Clinical Division (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery)
    • 2012 University of California-San Francisco - Pinnacle Award - Highest Patient Satisfaction Award For A Clinical Division at UCSF (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery)
    • 2013 University of California-San Francisco - Pinnacle Award (Honorable Mention / 3rd Place) - Highest Patient Satisfaction Award For A Clinical Division at UCSF (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery)

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Formeister EJ, Baum R, Knott PD, Seth R, Ha P, Ryan W, El-Sayed I, George J, Larson A, Plonowska K, Heaton C. Machine Learning for Predicting Complications in Head and Neck Microvascular Free Tissue Transfer. Laryngoscope. 2020 Jan 28. PMID: 31990084.
      View in: PubMed
    2. Rooper LM, Windon MJ, Hernandez T, Miles B, Ha PK, Ryan WR, Van Zante A, Eisele DW, D'Souza G, Fakhry C, Westra WH. HPV-positive Squamous Cell Carcinoma of the Larynx, Oral Cavity, and Hypopharynx: Clinicopathologic Characterization With Recognition of a Novel Warty Variant. Am J Surg Pathol. 2020 Jan 13. PMID: 31934915.
      View in: PubMed
    3. Fakhry C, Waterboer T, Westra WH, Rooper LM, Windon M, Troy T, Koch W, Gourin CG, Bender N, Yavvari S, Kiess AP, Miles BA, Ryan WR, Ha PK, Eisele DW, D'Souza G. Distinct biomarker and behavioral profiles of human papillomavirus-related oropharynx cancer patients by age. Oral Oncol. 2020 Feb; 101:104522. PMID: 31881446.
      View in: PubMed
    4. Han M, Stanford-Moore GB, Larson AR, Schoppy DW, Cognetti DM, Joshi AS, Houlton JJ, Ryan WR. Predictors of Mortality in HPV-Associated Oropharynx Carcinoma Treated With Surgery Alone. Laryngoscope. 2019 Nov 01. PMID: 31675132.
      View in: PubMed
    5. Larson AR, Kemmer J, Formeister E, El-Sayed I, Ha P, George J, Ryan W, Chan E, Heaton C. Beyond Depth of Invasion: Adverse Pathologic Tumor Features in Early Oral Tongue Squamous Cell Carcinoma. Laryngoscope. 2019 Aug 14. PMID: 31411752.
      View in: PubMed
    6. Goel AN, Sangar S, Mukdad L, Heaton CM, Ryan WR, Wang MB, Long JL, St John MA. Patterns of care and survival impact of adjuvant chemoradiotherapy for oropharyngeal cancer with intermediate-risk features. Head Neck. 2019 09; 41(9):3177-3186. PMID: 31107584.
      View in: PubMed
    7. Xu MJ, Plonowska KA, Gurman ZR, Humphrey AK, Ha PK, Wang SJ, El-Sayed IH, Heaton CM, George JR, Yom SS, Algazi AP, Ryan WR. Treatment modality impact on quality of life for human papillomavirus-associated oropharynx cancer. Laryngoscope. 2020 Feb; 130(2):E48-E56. PMID: 30919470.
      View in: PubMed
    8. Windon MJ, Waterboer T, Hillel AT, Chien W, Best S, Stewart C, Akst L, Troy T, Bender N, Miles B, Ryan WR, Mandal R, Pitman K, Eisele DW, Fakhry C, D'Souza G. Sex differences in HPV immunity among adults without cancer. Hum Vaccin Immunother. 2019; 15(7-8):1935-1941. PMID: 30650013.
      View in: PubMed
    9. Wu TJ, Ha PK, El-Sayed IH, George JR, Heaton CM, Ryan WR, Russell MD. Socioeconomic disparities in a population of patients undergoing total thyroidectomy for benign disease. Head Neck. 2019 03; 41(3):715-721. PMID: 30521675.
      View in: PubMed
    10. Plonowska KA, Strohl MP, Wang SJ, Ha PK, George JR, Heaton CM, El-Sayed IH, Mallen-St Clair J, Ryan WR. Human Papillomavirus-Associated Oropharyngeal Cancer: Patterns of Nodal Disease. Otolaryngol Head Neck Surg. 2019 03; 160(3):502-509. PMID: 30274544.
      View in: PubMed
    11. Plonowska KA, Ha PK, Ryan WR. Advanced head and neck surgical techniques: A survey of US otolaryngology resident perspectives. Auris Nasus Larynx. 2019 Apr; 46(2):272-278. PMID: 30170906.
      View in: PubMed
    12. Ryan WR, Plonowska KA, Gurman ZR, Aubin-Pouliot A, Chang JL. One-Year symptom outcomes after sialolithiasis treatment with sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2019 02; 129(2):396-402. PMID: 30151855.
      View in: PubMed
    13. Plonowska KA, Gurman ZR, Humphrey A, Chang JL, Ryan WR. One-year outcomes of sialendoscopic-assisted salivary duct surgery for sialadenitis without sialolithiasis. Laryngoscope. 2019 04; 129(4):890-896. PMID: 30152080.
      View in: PubMed
    14. Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, Asthana S, Chan V, Krummel MF. A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments. Nat Med. 2018 08; 24(8):1178-1191. PMID: 29942093.
      View in: PubMed
    15. Formeister EJ, Sean Alemi A, El-Sayed I, George JR, Ha P, Daniel Knott P, Ryan WR, Seth R, Tamplen ML, Heaton CM. Shorter interval between radiation therapy and salvage laryngopharyngeal surgery increases complication rates following microvascular free tissue transfer. Am J Otolaryngol. 2018 Sep - Oct; 39(5):548-552. PMID: 29908709.
      View in: PubMed
    16. Ryan WR, Plonowska K. Human Papillomavirus in the Mouth and Throat: More Widespread Than Expected? JAMA Otolaryngol Head Neck Surg. 2018 06 01; 144(6):525-526. PMID: 29800955.
      View in: PubMed
    17. Winchester D, Lehman J, Tello T, Chimato N, Hocker T, Kim S, Chang J, Markey J, Yom SS, Ryan W, Mully T, Hodge D, Otley C, Arron ST. Undifferentiated pleomorphic sarcoma: Factors predictive of adverse outcomes. J Am Acad Dermatol. 2018 Nov; 79(5):853-859. PMID: 29787841.
      View in: PubMed
    18. Chan CK, Han AY, Alonso JE, Xu MJ, Mallen-St Clair J, Heaton CM, Ryan WR, Kuan EC, St John MA. Squamous Cell Carcinoma of the Soft Palate in the United States: A Population-Based Study. Otolaryngol Head Neck Surg. 2018 10; 159(4):662-668. PMID: 29734872.
      View in: PubMed
    19. Windon MJ, D'Souza G, Rettig EM, Westra WH, van Zante A, Wang SJ, Ryan WR, Mydlarz WK, Ha PK, Miles BA, Koch W, Gourin C, Eisele DW, Fakhry C. Increasing prevalence of human papillomavirus-positive oropharyngeal cancers among older adults. Cancer. 2018 07 15; 124(14):2993-2999. PMID: 29710393.
      View in: PubMed
    20. Xu MJ, Wu TJ, van Zante A, El-Sayed IH, Algazi AP, Ryan WR, Ha PK, Yom SS. Mortality risk after clinical management of recurrent and metastatic adenoid cystic carcinoma. J Otolaryngol Head Neck Surg. 2018 Apr 25; 47(1):28. PMID: 29695289.
      View in: PubMed
    21. Zheng M, Plonowska KA, Strohl MP, Ryan WR. Surgeon-performed ultrasound for the assessment of parotid masses. Am J Otolaryngol. 2018 Sep - Oct; 39(5):467-471. PMID: 29778636.
      View in: PubMed
    22. Yin LX, D'Souza G, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig EM, Ryan WR, Ha PK, Wentz A, Koch W, Eisele DW, Fakhry C. Prognostic factors for human papillomavirus-positive and negative oropharyngeal carcinomas. Laryngoscope. 2018 08; 128(8):E287-E295. PMID: 29536542.
      View in: PubMed
    23. Togarrati PP, Dinglasan N, Desai S, Ryan WR, Muench MO. CD29 is highly expressed on epithelial, myoepithelial, and mesenchymal stromal cells of human salivary glands. Oral Dis. 2018 May; 24(4):561-572. PMID: 29197149.
      View in: PubMed
    24. Xu MJ, Lazar AA, Garsa AA, Arron ST, Ryan WR, El-Sayed IH, George JR, Algazi AP, Heaton CM, Ha PK, Yom SS. Major prognostic factors for recurrence and survival independent of the American Joint Committee on Cancer eighth edition staging system in patients with cutaneous squamous cell carcinoma treated with multimodality therapy. Head Neck. 2018 07; 40(7):1406-1414. PMID: 29524273.
      View in: PubMed
    25. Garcia SM, Tamaki S, Lee S, Wong A, Jose A, Dreux J, Kouklis G, Sbitany H, Seth R, Knott PD, Heaton C, Ryan WR, Kim EA, Hansen SL, Hoffman WY, Pomerantz JH. High-Yield Purification, Preservation, and Serial Transplantation of Human Satellite Cells. Stem Cell Reports. 2018 03 13; 10(3):1160-1174. PMID: 29478895.
      View in: PubMed
    26. Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM. Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med. 2018 03; 10(3). PMID: 29335337.
      View in: PubMed
    27. Alonso JE, Han AY, Kuan EC, Strohl M, Clair JM, St John MA, Ryan WR, Heaton CM. The survival impact of surgical therapy in squamous cell carcinoma of the hard palate. Laryngoscope. 2018 09; 128(9):2050-2055. PMID: 29399797.
      View in: PubMed
    28. William R. Ryan, A. Sean Alemi, Annemieke van Zante. Salivary Fine Needle Aspiration Biopsy. Gland-Preserving Salivary Surgery. 2018 Jan 1; 27-37.
      View in: Publisher Site
    29. Zhou MJ, van Zante A, Lazar AA, Groppo ER, Garsa AA, Ryan WR, El-Sayed IH, Eisele DW, Yom SS. Squamous cell carcinoma of unknown primary of the head and neck: Favorable prognostic factors comparable to those in oropharyngeal cancer. Head Neck. 2018 05; 40(5):904-916. PMID: 29210145.
      View in: PubMed
    30. Tamplen ML, Tamplen J, Shuman E, Heaton CM, George JR, Wang SJ, Ryan WR. Comparison of Output Volume Thresholds for Drain Removal After Selective Lateral Neck Dissection: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2017 12 01; 143(12):1195-1199. PMID: 28837725.
      View in: PubMed
    31. Strohl MP, Dewyer NA, Sckolnick J, Ryan WR. A Novel Approach to Oropharyngeal Foreign Body Removal. Otolaryngol Head Neck Surg. 2018 01; 158(1):194-196. PMID: 29039243.
      View in: PubMed
    32. M. Xu, A.A. Garsa, A. Lazar, S. Arron, W.R. Ryan, I. El-Sayed, J. George, A. Algazi, C. Heaton, P. Ha, S.S. Yom. Prognostic Factors for Recurrence and Survival Independent of the Revised AJCC 8th Edition Staging System in Patients with Cutaneous Squamous Cell Carcinoma Treated with Multimodality Therapy. International Journal of Radiation Oncology • Biology • Physics. 2017 Oct 1; 99(2):e383.
      View in: Publisher Site
    33. C.H. Chapman, W.R. Ryan, S.S. Yom. Prevalence of Highly Self-Directed Care Among Patients with HPV-Associated Oropharyngeal Cancer. International Journal of Radiation Oncology • Biology • Physics. 2017 Oct 1; 99(2):e327.
      View in: Publisher Site
    34. Larson AR, Aubin-Pouliot A, Delagnes E, Zheng M, Chang JL, Ryan WR. Surgeon-Performed Ultrasound for Chronic Obstructive Sialadenitis Helps Predict Sialendoscopic Findings and Outcomes. Otolaryngol Head Neck Surg. 2017 12; 157(6):973-980. PMID: 28871894.
      View in: PubMed
    35. Puskas JD, Bavaria JE, Svensson LG, Blackstone EH, Griffith B, Gammie JS, Heimansohn DA, Sadowski J, Bartus K, Johnston DR, Rozanski J, Rosengart T, Girardi LN, Klodell CT, Mumtaz MA, Takayama H, Halkos M, Starnes V, Boateng P, Timek TA, Ryan W, Omer S, Smith CR. The COMMENCE trial: 2-year outcomes with an aortic bioprosthesis with RESILIA tissue. Eur J Cardiothorac Surg. 2017 Sep 01; 52(3):432-439. PMID: 28605428.
      View in: PubMed
    36. Delagnes EA, Zheng M, Aubin-Pouliot A, Chang JL, Ryan WR. Salivary duct stenosis: Short-term symptom outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 12; 127(12):2770-2776. PMID: 28714528.
      View in: PubMed
    37. Naunheim M, Wu X, Ryan WR, Wang SJ, Heaton CM. Volumetric Growth Rate of Recurrent Pleomorphic Adenoma. Ann Otol Rhinol Laryngol. 2017 Jul; 126(7):544-547. PMID: 28604082.
      View in: PubMed
    38. Togarrati PP, Sasaki RT, Abdel-Mohsen M, Dinglasan N, Deng X, Desai S, Emmerson E, Yee E, Ryan WR, da Silva MCP, Knox SM, Pillai SK, Muench MO. Identification and characterization of a rich population of CD34+ mesenchymal stem/stromal cells in human parotid, sublingual and submandibular glands. Sci Rep. 2017 06 14; 7(1):3484. PMID: 28615711.
      View in: PubMed
    39. Margaret J. Zhou, Annemieke Van Zante, Ann A. Lazar, Eli R. Groppo, Adam A. Garsa, William R. Ryan, Ivan H. El-Sayed, David W. Eisele, Sue S. Yom. (P060) Squamous Cell Carcinoma of Unknown Primary of the Head and Neck: “Low-Risk” Prognostic Factors for Disease Control and Survival Reminiscent of Oropharyngeal Cancers. International Journal of Radiation Oncology • Biology • Physics. 2017 Jun 1; 98(2):e31.
      View in: Publisher Site
    40. Melody J. Xu, Adam A. Garsa, Ann Lazar, Sarah T. Arron, William R. Ryan, Ivan El-Sayed, Alain A. Algazi, Jonathan George, Patrick Ha, Sue S. Yom. (P069) Prognostic Factors for Recurrence and Survival Independent of the Revised AJCC 8th Edition Staging System in Patients With Cutaneous Squamous Cell Carcinoma. International Journal of Radiation Oncology • Biology • Physics. 2017 Jun 1; 98(2):e33-e34.
      View in: Publisher Site
    41. Markey JD, Morrel WG, Wang SJ, Ryan WR. The effect of submandibular gland preservation during level 1B neck dissection on postoperative xerostomia. Auris Nasus Larynx. 2018 Feb; 45(1):123-127. PMID: 28449980.
      View in: PubMed
    42. Ghosh P, Lazar AA, Ryan WR, Yom SS. A feasibility and efficacy trial of a hand-held humidification device in patients undergoing radiotherapy for head and neck cancer. Support Care Cancer. 2017 08; 25(8):2611-2618. PMID: 28353039.
      View in: PubMed
    43. Fakhry C, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig E, Yin LX, Ryan WR, Ha PK, Wentz A, Koch W, Richmon JD, Eisele DW, D'Souza G. The prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer. Cancer. 2017 05 01; 123(9):1566-1575. PMID: 28241096.
      View in: PubMed
    44. D'Souza G, Westra WH, Wang SJ, van Zante A, Wentz A, Kluz N, Rettig E, Ryan WR, Ha PK, Kang H, Bishop J, Quon H, Kiess AP, Richmon JD, Eisele DW, Fakhry C. Differences in the Prevalence of Human Papillomavirus (HPV) in Head and Neck Squamous Cell Cancers by Sex, Race, Anatomic Tumor Site, and HPV Detection Method. JAMA Oncol. 2017 Feb 01; 3(2):169-177. PMID: 27930766.
      View in: PubMed
    45. Tamplen ML, Tamplen J, Torrecillas V, Seth R, Ricceri S, Hemmat S, Heaton C, Ryan WR, Knott PD. Does a Standalone Cancer Center Improve Head and Neck Microsurgical Outcomes? J Reconstr Microsurg. 2017 May; 33(4):252-256. PMID: 28061519.
      View in: PubMed
    46. Heaton CM, Ahmed SR, Ryan WR. Transoral robotic surgery (TORS) for excision of a retropharyngeal intramuscular lipoma. Auris Nasus Larynx. 2017 Dec; 44(6):742-744. PMID: 27956103.
      View in: PubMed
    47. Jáuregui E, Kiringoda R, Ryan WR, Eisele DW, Chang JL. Chronic parotitis with multiple calcifications: Clinical and sialendoscopic findings. Laryngoscope. 2017 07; 127(7):1565-1570. PMID: 27861944.
      View in: PubMed
    48. Yu Y, Mabray M, Silveira W, Shen PY, Ryan WR, Uzelac A, Yom SS. Earlier and more specific detection of persistent neck disease with diffusion-weighted MRI versus subsequent PET/CT after definitive chemoradiation for oropharyngeal squamous cell carcinoma. Head Neck. 2017 03; 39(3):432-438. PMID: 27726241.
      View in: PubMed
    49. Delagnes EA, Aubin-Pouliot A, Zheng M, Chang JL, Ryan WR. Sialadenitis without sialolithiasis: Prospective outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 05; 127(5):1073-1079. PMID: 27701754.
      View in: PubMed
    50. Alemi AS, Heaton CM, Ryan WR, El-Sayed I, Wang SJ. Volumetric Growth of Cervical Schwannoma as a Predictor of Surgical Intervention. Otolaryngol Head Neck Surg. 2017 01; 156(1):152-155. PMID: 27625027.
      View in: PubMed
    51. Hemmat SM, Wang SJ, Ryan WR. Neck Dissection Technique Commonality and Variance: A Survey on Neck Dissection Technique Preferences among Head and Neck Oncologic Surgeons in the American Head and Neck Society. Int Arch Otorhinolaryngol. 2017 Jan; 21(1):8-16. PMID: 28050201.
      View in: PubMed
    52. Heaton CM, Yu K, Calkins S, George JR, Ryan WR, Wang SJ. Clinicopathologic characteristics and outcomes of recurrent oropharyngeal squamous cell carcinoma. Am J Otolaryngol. 2016 Nov - Dec; 37(6):513-516. PMID: 27522438.
      View in: PubMed
    53. Hemmat S, Wang SJ, Ryan WR. How, when, and from whom neck dissection operative technique is learned: An international survey on neck dissection education among head and neck oncologic surgeons. Am J Otolaryngol. 2016 Sep-Oct; 37(5):431-5. PMID: 27221027.
      View in: PubMed
    54. Tamplen ML, Ricceri S, Hemmat S, Seth R, Ryan WR, Knott PD. Benefits of Immediate Extubation Following Free Tissue Transfer for Head and Neck Reconstruction. J Reconstr Microsurg. 2016 Sep; 32(7):533-9. PMID: 27110906.
      View in: PubMed
    55. Singer L, Calkins SM, Horvai AE, Ryan WR, Yom SS. Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer. J Otolaryngol Head Neck Surg. 2016 Mar 24; 45:20. PMID: 27009318.
      View in: PubMed
    56. Aubin-Pouliot A, Delagnes EA, Chang JL, Ryan WR. Sialendoscopy-assisted surgery and the chronic obstructive sialadenitis symptoms questionnaire: A prospective study. Laryngoscope. 2016 06; 126(6):1343-8. PMID: 26972293.
      View in: PubMed
    57. Y. Yu, M. Mabray, W.R. Silveira, P.Y. Shen, W.R. Ryan, A. Uzelac, S.S. Yom. Early Detection of Persistent Neck Disease With Diffusion-Weighted MRI Following Chemoradiation for Squamous Cell Carcinomas of the Oropharynx. International Journal of Radiation Oncology • Biology • Physics. 2015 Nov 1; 93(3):e347.
      View in: Publisher Site
    58. Markey JD, Seth R, Wang SJ, Ryan WR, El-Sayed IH, Knott PD. Anterolateral Thigh Adipofascial Flap: A New Option for Scalp Reconstruction. J Reconstr Microsurg. 2016 Feb; 32(2):160-3. PMID: 26340759.
      View in: PubMed
    59. Schwalje AT, Uzelac A, Ryan WR. Growth rate characteristics of Warthin's tumours of the parotid gland. Int J Oral Maxillofac Surg. 2015 Dec; 44(12):1474-9. PMID: 26314235.
      View in: PubMed
    60. Aubin-Pouliot A, Delagnes EA, Eisele DW, Chang JL, Ryan WR. The Chronic Obstructive Sialadenitis Symptoms Questionnaire to assess sialendoscopy-assisted surgery. Laryngoscope. 2016 Jan; 126(1):93-9. PMID: 26256263.
      View in: PubMed
    61. Heaton CM, Al-Shwaiheen F, Liu CS, Yom SS, Ryan WR. Prognostic significance of hyoid bone invasion in advanced base of tongue carcinoma treated by chemoradiation. Clin Otolaryngol. 2015 Jun; 40(3):260-5. PMID: 25641627.
      View in: PubMed
    62. Hemmat SM, Wang SJ, Uzelac A, Yom SS, Ryan WR. The Limitations of Routine Magnetic Resonance Imaging for Long-Term Post-Treatment Locoregional Surveillance of Salivary Carcinoma. ORL J Otorhinolaryngol Relat Spec. 2015; 77(3):132-40. PMID: 26022374.
      View in: PubMed
    63. Goepfert RP, Liu C, Ryan WR. Trans-oral robotic surgery and surgeon-performed trans-oral ultrasound for intraoperative location and excision of an isolated retropharyngeal lymph node metastasis of papillary thyroid carcinoma. Am J Otolaryngol. 2015 Sep-Oct; 36(5):710-4. PMID: 25964171.
      View in: PubMed
    64. Al-Shwaiheen FA, Wang SJ, Uzelac A, Yom SS, Ryan WR. The advantages and drawbacks of routine magnetic resonance imaging for long-term post-treatment locoregional surveillance of oral cavity squamous cell carcinoma. Am J Otolaryngol. 2015 May-Jun; 36(3):415-23. PMID: 25697087.
      View in: PubMed
    65. Goepfert RP, Yom SS, Ryan WR, Cheung SW. Development of a chemoradiation therapy toxicity staging system for oropharyngeal carcinoma. Laryngoscope. 2015 Apr; 125(4):869-76. PMID: 25388529.
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    66. Prendes BL, Aubin-Pouliot A, Egbert N, Ryan WR. Elective lymphadenectomy during salvage for locally recurrent head and neck squamous cell carcinoma after radiation. Otolaryngol Head Neck Surg. 2014 Sep; 151(3):462-7. PMID: 24894423.
      View in: PubMed
    67. Ryan WR, Chang JL, Eisele DW. Surgeon-performed ultrasound and transfacial sialoendoscopy for complete parotid duct stenosis. Laryngoscope. 2014 Feb; 124(2):418-20. PMID: 24130099.
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    68. Chase Heaton, Chia-Shang Liu, Fatemah Al-Shwaiheen, William R. Ryan. Prognostic Significance of Hyoid Bone Invasion in Advanced Base of Tongue Carcinoma Treated by Chemoradiation. Otolaryngology. 2013 Sep 1; 149(2_suppl):p187-p188.
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    69. W.R. Silveira, P.Y. Shen, J. Tan, C.M. Glastonbury, J.M. Quivey, W.R. Ryan, S.J. Wang, S.S. Yom. Diffusion-Weighted Imaging Compared to 3-month PET/CT to Predict Response in the Irradiated Neck. International Journal of Radiation Oncology • Biology • Physics. 2012 Nov 1; 84(3):s475.
      View in: Publisher Site
    70. Ryan WR, Orloff LA. Intraoperative tumor localization with surgeon-performed ultrasound-guided needle dye injection. Laryngoscope. 2011 Aug; 121(8):1651-5. PMID: 21660975.
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    71. Ryan WR, Ramachandra T, Hwang PH. Correlations between symptoms, nasal endoscopy, and in-office computed tomography in post-surgical chronic rhinosinusitis patients. Laryngoscope. 2011 Mar; 121(3):674-8. PMID: 21305550.
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    72. Ryan WR, Hwang PH. Safety of a preservative-free acidified saline nasal spray: a randomized, double-blind, placebo-controlled, crossover clinical trial. Arch Otolaryngol Head Neck Surg. 2010 Nov; 136(11):1099-103. PMID: 21079163.
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    73. Ryan WR, Most SP. A prospective evaluation of the efficacy of topical adhesive pads for the reduction of facial rhytids. Arch Facial Plast Surg. 2009 Jul-Aug; 11(4):252-6. PMID: 19620531.
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    74. Ryan WR, Fee WE. Long-term great auricular nerve morbidity after sacrifice during parotidectomy. Laryngoscope. 2009 Jun; 119(6):1140-6. PMID: 19399835.
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    75. Ryan WR, Fee WE. Great auricular nerve morbidity after nerve sacrifice during parotidectomy. Arch Otolaryngol Head Neck Surg. 2006 Jun; 132(6):642-9. PMID: 16785410.
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    76. Ryan WR, Fee WE, Le QT, Pinto HA. Positron-emission tomography for surveillance of head and neck cancer. Laryngoscope. 2005 Apr; 115(4):645-50. PMID: 15805874.
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    77. Ryan WR, Allan RN, Yamamoto T, Keighley MR. Crohn's disease patients who quit smoking have a reduced risk of reoperation for recurrence. Am J Surg. 2004 Feb; 187(2):219-25. PMID: 14769308.
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    78. Ryan WR, Ley C, Allan RN, Keighley MR. Patients with Crohn's disease are unaware of the risks that smoking has on their disease. J Gastrointest Surg. 2003 Jul-Aug; 7(5):706-11. PMID: 12850686.
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    79. Quigley TM, Ryan WR, Morgan S. Patient satisfaction after carotid endarterectomy using a selective policy of local anesthesia. Am J Surg. 2000 May; 179(5):382-5. PMID: 10930485.
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    80. Fisher RL, Ryan WR, Dugdale TW, Zimmermann GA. Arthroscopic ankle fusion. Conn Med. 1997 Oct; 61(10):643-6. PMID: 9375450.
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    81. Panigrahi K, Delmas PD, Singer F, Ryan W, Reiss O, Fisher R, Miller PD, Mizrahi I, Darte C, Kress BC. Characteristics of a two-site immunoradiometric assay for human skeletal alkaline phosphatase in serum. Clin Chem. 1994 May; 40(5):822-8. PMID: 8174258.
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    82. Ho JJ, Chung YS, Ryan W, Henslee JG, Kim YS. Evaluation of factors affecting the performance of enzymatic SPan-1 immunoassays for pancreatic cancer. J Immunol Methods. 1989 Dec 20; 125(1-2):97-104. PMID: 2691579.
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    83. Ho JJ, Chung YS, Fujimoto Y, Bi N, Ryan W, Yuan SZ, Byrd JC, Kim YS. Mucin-like antigens in a human pancreatic cancer cell line identified by murine monoclonal antibodies SPan-1 and YPan-1. Cancer Res. 1988 Jul 15; 48(14):3924-31. PMID: 2454732.
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    84. Ryan W, Gates GA, Cantu E, Hearne EM. Current status of laryngectomee rehabilitation: III. understanding of esophageal speech. Am J Otolaryngol. 1982 Mar-Apr; 3(2):91-6. PMID: 7091545.
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    85. Gates GA, Ryan W, Lauder E. Current status of laryngectomee rehabilitation: IV. attitudes about laryngectomee rehabilitation should change. Am J Otolaryngol. 1982 Mar-Apr; 3(2):97-103. PMID: 7091546.
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    86. Gates GA, Ryan W, Cantu E, Hearne E. Current status of laryngectomee rehabilitation: II. Causes of failure. Am J Otolaryngol. 1982 Jan-Feb; 3(1):8-14. PMID: 7114393.
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    87. Gates GA, Ryan W, Cooper JC, Lawlis GF, Cantu E, Hayashi T, Lauder E, Welch RW, Hearne E. Current status of laryngectomee rehabilitation: I. Results of therapy. Am J Otolaryngol. 1982 Jan-Feb; 3(1):1-7. PMID: 7114387.
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    88. Gibson JG, Tullis JL, Tinch RJ, Ryan WR, DiForte S. The post-thaw viability of red blood cells of ACD and CPD blood preserved in the frozen state with and without added adenine. Transfusion. 1972 May-Jun; 12(3):198-207. PMID: 5026173.
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