Loading...

Clay Gustafson, MD, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentPediatrics
Address1450 3rd Street
San Francisco CA 94158
EmailClay.Gustafson@ucsf.edu
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Rice University, Houston, TexasBA1996Biochemistry/English Literature
    University of Texas Medical BranchMD, PhD2005Medicine/Biochemistry and Genetics
    University of Texas SouthwesternPediatrics Residency2008Pediatrics
    University of California San FranciscoHematology/Oncology Fellowship2012Pediatric Hematology/Oncology
    Collapse Awards and Honors
    Alex's Lemonade Stand2012  - 2014ALSF "A" Award

    Collapse Overview 

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Clinical Trials
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Fan Q, Aksoy O, Wong RA, Ilkhanizadeh S, Novotny CJ, Gustafson C, Truong AY, Cayanan G, Simonds EF, Haas-Kogan D, Phillips JJ, Nicolaides T, Okaniwa M, Shokat KM, Weiss WA. A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma. Cancer Cell. 2017 Mar 13; 31(3):424-435. PMID: 28292440.
      View in: PubMed
    2. Vo KT, Karski EE, Nasholm NM, Allen S, Hollinger F, Gustafson C, Long-Boyle JR, Shiboski S, Matthay KK, DuBois SG. Phase 1 study of sirolimus in combination with oral cyclophosphamide and topotecan in children and young adults with relapsed and refractory solid tumors. Oncotarget. 2016 Oct 25. PMID: 27793021.
      View in: PubMed
    3. Lee JK, Phillips JW, Smith BA, Park JW, Stoyanova T, McCaffrey EF, Baertsch R, Sokolov A, Meyerowitz JG, Mathis C, Cheng D, Stuart JM, Shokat KM, Gustafson C, Huang J, Witte ON. N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. Cancer Cell. 2016 Apr 11; 29(4):536-47. PMID: 27050099.
      View in: PubMed
    4. Yu D, Dong Z, Gustafson C, Ruiz-González R, Signor L, Marzocca F, Borel F, Klassen MP, Makhijani K, Royant A, Jan YN, Weiss WA, Guo S, Shu X. Rational design of a monomeric and photostable far-red fluorescent protein for fluorescence imaging in vivo. Protein Sci. 2016 Feb; 25(2):308-15. PMID: 26549191.
      View in: PubMed
    5. Lee JS, Wu R, Wong T, DuBois SG, Matthay K, Gustafson C, Hawkins R, Roy-Burman A. Extended Sedation With Continuous Midazolam or Dexmedetomidine Infusion for Young Children Receiving (131) I-MIBG Radiopharmaceutical Therapy for Advanced Neuroblastoma. Pediatr Blood Cancer. 2016 Mar; 63(3):471-8. PMID: 26585842.
      View in: PubMed
    6. Temple W, Mendelsohn L, Kim GE, Nekritz E, Gustafson C, Lin L, Giacomini K, Naranjo A, Van Ryn C, Yanik GA, Kreissman SG, Hogarty M, Matthay KK, DuBois SG. Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's Oncology Group. Eur J Nucl Med Mol Imaging. 2016 Mar; 43(3):474-81. PMID: 26338179.
      View in: PubMed
    7. Cage TA, Chanthery Y, Chesler L, Grimmer M, Knight Z, Shokat K, Weiss WA, Gustafson WC. Downregulation of MYCN through PI3K Inhibition in Mouse Models of Pediatric Neural Cancer. Front Oncol. 2015; 5:111. PMID: 26029667; PMCID: PMC4429235.
    8. Meyerowitz JG, Weiss WA, Gustafson C. A new "angle" on kinase inhibitor design: Prioritizing amphosteric activity above kinase inhibition. Mol Cell Oncol. 2015 Apr-Jun; 2(2):e975641. PMID: 27308435.
      View in: PubMed
    9. Chen J, Hackett CS, Zhang S, Song YK, Bell RJ, Molinaro AM, Quigley DA, Balmain A, Song JS, Costello JF, Gustafson WC, Van Dyke T, Kwok PY, Khan J, Weiss WA. The genetics of splicing in neuroblastoma. Cancer Discov. 2015 Apr; 5(4):380-95. PMID: 25637275; PMCID: PMC4390477.
    10. Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, Kozlov S, Mao JH, Van Dyke T, Kwok PY, Khan J, Balmain A, Fan Q, Weiss WA. Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. Cell Rep. 2014 Nov 6; 9(3):1034-46. PMID: 25437558; PMCID: PMC4251494.
    11. Gustafson WC, Meyerowitz JG, Nekritz EA, Chen J, Benes C, Charron E, Simonds EF, Seeger R, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA. Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell. 2014 Sep 8; 26(3):414-27. PMID: 25175806; PMCID: PMC4160413.
    12. Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X. An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. Nat Commun. 2014; 5:3626. PMID: 24832154; PMCID: PMC4077998.
    13. Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, Fouse SD, Yamamoto S, Ueda H, Tatsuno K, Asthana S, Jalbert LE, Nelson SJ, Bollen AW, Gustafson WC, Charron E, Weiss WA, Smirnov IV, Song JS, Olshen AB, Cha S, Zhao Y, Moore RA, Mungall AJ, Jones SJ, Hirst M, Marra MA, Saito N, Aburatani H, Mukasa A, Berger MS, Chang SM, Taylor BS, Costello JF. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science. 2014 Jan 10; 343(6167):189-93. PMID: 24336570; PMCID: PMC3998672.
    14. Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 2013 Oct 14; 24(4):438-49. PMID: 24135280; PMCID: PMC3819146.
    15. Puissant A, Frumm SM, Alexe G, Bassil CF, Qi J, Chanthery YH, Nekritz EA, Zeid R, Gustafson WC, Greninger P, Garnett MJ, McDermott U, Benes CH, Kung AL, Weiss WA, Bradner JE, Stegmaier K. Targeting MYCN in neuroblastoma by BET bromodomain inhibition. Cancer Discov. 2013 Mar; 3(3):308-23. PMID: 23430699; PMCID: PMC3672953.
    16. Seo Y, Gustafson WC, Dannoon SF, Nekritz EA, Lee CL, Murphy ST, VanBrocklin HF, Hernandez-Pampaloni M, Haas-Kogan DA, Weiss WA, Matthay KK. Tumor dosimetry using [124I]m-iodobenzylguanidine microPET/CT for [131I]m-iodobenzylguanidine treatment of neuroblastoma in a murine xenograft model. Mol Imaging Biol. 2012 Dec; 14(6):735-42. PMID: 22382618; PMCID: PMC3369020.
    17. Cheng CK, Gustafson WC, Charron E, Houseman BT, Zunder E, Goga A, Gray NS, Pollok B, Oakes SA, James CD, Shokat KM, Weiss WA, Fan QW. Dual blockade of lipid and cyclin-dependent kinases induces synthetic lethality in malignant glioma. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12722-7. PMID: 22802621; PMCID: PMC3411950.
    18. Chanthery YH, Gustafson WC, Itsara M, Persson A, Hackett CS, Grimmer M, Charron E, Yakovenko S, Kim G, Matthay KK, Weiss WA. Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma. Sci Transl Med. 2012 Jan 4; 4(115):115ra3. PMID: 22218692; PMCID: PMC3402217.
    19. Gustafson WC, Matthay KK. Progress towards personalized therapeutics: biologic- and risk-directed therapy for neuroblastoma. Expert Rev Neurother. 2011 Oct; 11(10):1411-23. PMID: 21955198.
      View in: PubMed
    20. Gustafson WC, Weiss WA. Addiction to B-MYB. Oncotarget. 2010 Aug; 1(4):235-6. PMID: 21304174; PMCID: PMC3248101.
    21. Gustafson WC, Weiss WA. Myc proteins as therapeutic targets. Oncogene. 2010 Mar 4; 29(9):1249-59. PMID: 20101214; PMCID: PMC2904682.
    22. Gustafson WC, De Berry BB, Evers BM, Chung DH. Role of gastrointestinal hormones in neuroblastoma. World J Surg. 2005 Mar; 29(3):281-6. PMID: 15706438.
      View in: PubMed
    23. Ray S, Lu Y, Kaufmann SH, Gustafson WC, Karp JE, Boldogh I, Fields AP, Brasier AR. Genomic mechanisms of p210BCR-ABL signaling: induction of heat shock protein 70 through the GATA response element confers resistance to paclitaxel-induced apoptosis. J Biol Chem. 2004 Aug 20; 279(34):35604-15. PMID: 15155749.
      View in: PubMed
    24. Gustafson WC, Ray S, Jamieson L, Thompson EA, Brasier AR, Fields AP. Bcr-Abl regulates protein kinase Ciota (PKCiota) transcription via an Elk1 site in the PKCiota promoter. J Biol Chem. 2004 Mar 5; 279(10):9400-8. PMID: 14670960.
      View in: PubMed
    25. Fields AP, Murray NR, Gustafson WC. Characterization of the role of protein kinase C isozymes in colon carcinogenesis using transgenic mouse models. Methods Mol Biol. 2003; 233:539-53. PMID: 12840533.
      View in: PubMed
    26. Fields AP, Gustafson WC. Protein kinase C in disease: cancer. Methods Mol Biol. 2003; 233:519-37. PMID: 12840532.
      View in: PubMed
    27. Chen L, Finnerty C, Gustafson WC, Bush CR, Chi P, Guo H, Luxon B, Fields AP, Thompson EA. Genomic analysis of glucocorticoid-regulated promoters in murine T-lymphoma cells. Recent Prog Horm Res. 2003; 58:155-74. PMID: 12795418.
      View in: PubMed
    28. Stuart CA, Wen G, Gustafson WC, Thompson EA. Comparison of GLUT1, GLUT3, and GLUT4 mRNA and the subcellular distribution of their proteins in normal human muscle. Metabolism. 2000 Dec; 49(12):1604-9. PMID: 11145124.
      View in: PubMed
    29. Gustafson WC, Taylor CW, Valdez BC, Henning D, Phippard A, Ren Y, Busch H, Durban E. Nucleolar protein p120 contains an arginine-rich domain that binds to ribosomal RNA. Biochem J. 1998 Apr 15; 331 ( Pt 2):387-93. PMID: 9531475; PMCID: PMC1219366.
    30. Ren Y, Busch R, Durban E, Taylor C, Gustafson WC, Valdez B, Li YP, Smetana K, Busch H. Overexpression of human nucleolar proteins in insect cells: characterization of nucleolar protein p120. Protein Expr Purif. 1996 Mar; 7(2):212-9. PMID: 8812864.
      View in: PubMed
    31. Durban E, Valdez BC, Gustafson WC, Taylor CW, Cardellini E, Busch H. Functional domains of nucleolar phosphoprotein p120. Physiol Chem Phys Med NMR. 1995; 27(4):303-11. PMID: 8768786.
      View in: PubMed
    Clay's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _
    Back to TOP