Roberto Ricardo Gonzalez, MD, PhD

Title(s)Associate Professor, Dermatology
SchoolSchool of Medicine
Address513 Parnassus Ave, MSB, #1004
San Francisco CA 94117
Phone--
ORCID ORCID Icon0000-0002-6135-4035 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Puerto Rico - MayagüezB.S.2001Industrial Biotechnology
    Stanford University School of MedicinePh.D.2009Immunology
    Stanford University School of MedicineM.D.2011Medicine
    Brigham and Women's HospitalInternship2012Internal Medicine
    University of California San FranciscoResidency2015Dermatology
    University of California San FranciscoFellowship2016Dermatology
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    Robert Wood Johnson Foundation2017Harold Amos Medical Faculty Development Program

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Elucidating the role of type 2 immunity in skin homeostasis
    NIH K08AR075880Sep 24, 2019 - Aug 31, 2024
    Role: Principal Investigator
    Minority Predoctoral Fellowship Program
    NIH F31AI066402Sep 30, 2005 - Sep 29, 2009
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Innate type 2 immunity controls hair follicle commensalism by Demodex mites. Immunity. 2022 10 11; 55(10):1891-1908.e12. Ricardo-Gonzalez RR, Kotas ME, O'Leary CE, Singh K, Damsky W, Liao C, Arouge E, Tenvooren I, Marquez DM, Schroeder AW, Cohen JN, Fassett MS, Lee J, Daniel SG, Bittinger K, Díaz RE, Fraser JS, Ali N, Ansel KM, Spitzer MH, Liang HE, Locksley RM. PMID: 36044899; PMCID: PMC9561030.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    2. 012 Tissue-specific manipulation of regulatory T cells reveals the skin to be a site of immune tolerance. Journal of Investigative Dermatology. 2022 Aug 1; 142(8):s2. Cohen CJ, Moreau MJ, Gouirand GV, Macon MC, Boothby BI, Gratz GI, Stoecklinger SA, Weaver WC, Sharpe SA, Ricardo-Gonzalez RR, Rosenblum RM. .
      View in: Publisher Site   Mentions:
    3. Classification of human chronic inflammatory skin disease based on single-cell immune profiling. Sci Immunol. 2022 04 15; 7(70):eabl9165. Liu Y, Wang H, Taylor M, Cook C, Martínez-Berdeja A, North JP, Harirchian P, Hailer AA, Zhao Z, Ghadially R, Ricardo-Gonzalez RR, Grekin RC, Mauro TM, Kim E, Choi J, Purdom E, Cho RJ, Cheng JB. PMID: 35427179; PMCID: PMC9301819.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    4. Bile acid-sensitive tuft cells regulate biliary neutrophil influx. Sci Immunol. 2022 03 04; 7(69):eabj1080. O'Leary CE, Sbierski-Kind J, Kotas ME, Wagner JC, Liang HE, Schroeder AW, de Tenorio JC, von Moltke J, Ricardo-Gonzalez RR, Eckalbar WL, Molofsky AB, Schneider C, Locksley RM. PMID: 35245089; PMCID: PMC9166270.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    5. ILC2s - development, divergence, dispersal. Curr Opin Immunol. 2022 04; 75:102168. Ricardo-Gonzalez RR, Molofsky AB, Locksley RM. PMID: 35176675; PMCID: PMC9131705.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    6. CISH constrains the tuft-ILC2 circuit to set epithelial and immune tone. Mucosal Immunol. 2021 11; 14(6):1295-1305. Kotas ME, Mroz NM, Koga S, Liang HE, Schroeder AW, Ricardo-Gonzalez RR, Schneider C, Locksley RM. PMID: 34290377; PMCID: PMC8528700.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    7. A role for IL-33-activated ILC2s in eosinophilic vasculitis. JCI Insight. 2021 06 22; 6(12). Kotas ME, Dion J, Van Dyken S, Ricardo-Gonzalez RR, Danel CJ, Taillé C, Mouthon L, Locksley RM, Terrier B. PMID: 33974563; PMCID: PMC8262498.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    8. Skin-resident innate lymphoid cells converge on a pathogenic effector state. Nature. 2021 04; 592(7852):128-132. Bielecki P, Riesenfeld SJ, Hütter JC, Torlai Triglia E, Kowalczyk MS, Ricardo-Gonzalez RR, Lian M, Amezcua Vesely MC, Kroehling L, Xu H, Slyper M, Muus C, Ludwig LS, Christian E, Tao L, Kedaigle AJ, Steach HR, York AG, Skadow MH, Yaghoubi P, Dionne D, Jarret A, McGee HM, Porter CBM, Licona-Limón P, Bailis W, Jackson R, Gagliani N, Gasteiger G, Locksley RM, Regev A, Flavell RA. PMID: 33536623; PMCID: PMC8336632.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    9. Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation. iScience. 2020 Oct 23; 23(10):101582. Liu Y, Cook C, Sedgewick AJ, Zhang S, Fassett MS, Ricardo-Gonzalez RR, Harirchian P, Kashem SW, Hanakawa S, Leistico JR, North JP, Taylor MA, Zhang W, Man MQ, Charruyer A, Beliakova-Bethell N, Benz SC, Ghadially R, Mauro TM, Kaplan DH, Kabashima K, Choi J, Song JS, Cho RJ, Cheng JB. PMID: 33205009; PMCID: PMC7648132.
      View in: PubMed   Mentions: 17  
    10. 716 Supporting diversity in skin science: Development of a summer curriculum for underrepresented minority medical students. Journal of Investigative Dermatology. 2020 Jul 1; 140(7):s96. Paul PM, Lester LJ, Ricardo-Gonzalez RR, Naik NH. .
      View in: Publisher Site   Mentions:
    11. 095 Single-cell Profiling Reveals a Highly Specific, Compartmentalized Functional Response in the Cutaneous Immune System. Journal of Investigative Dermatology. 2020 Jul 1; 140(7):s11. Liu LY, Cook CC, Haririchian HP, Ricardo-Gonzalez RR, North NJ, Charruyer CA, Ghadially GR, Cho CR, Cheng CJ. .
      View in: Publisher Site   Mentions:
    12. Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity. J Exp Med. 2020 04 06; 217(4). Ricardo-Gonzalez RR, Schneider C, Liao C, Lee J, Liang HE, Locksley RM. PMID: 32031571; PMCID: PMC7144525.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    13. Skin-Resident Innate Lymphoid Cells - Cutaneous Innate Guardians and Regulators. Trends Immunol. 2020 02; 41(2):100-112. Kobayashi T, Ricardo-Gonzalez RR, Moro K. PMID: 31948873; PMCID: PMC7364860.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    14. ILC2s chew the fat. J Exp Med. 2019 09 02; 216(9):1972-1973. Ricardo-Gonzalez RR, Locksley RM. PMID: 31405894; PMCID: PMC6719424.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    15. Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming. Immunity. 2019 06 18; 50(6):1425-1438.e5. Schneider C, Lee J, Koga S, Ricardo-Gonzalez RR, Nussbaum JC, Smith LK, Villeda SA, Liang HE, Locksley RM. PMID: 31128962; PMCID: PMC6645687.
      View in: PubMed   Mentions: 112     Fields:    Translation:AnimalsCells
    16. Tissue signals imprint ILC2 identity with anticipatory function. Nat Immunol. 2018 10; 19(10):1093-1099. Ricardo-Gonzalez RR, Van Dyken SJ, Schneider C, Lee J, Nussbaum JC, Liang HE, Vaka D, Eckalbar WL, Molofsky AB, Erle DJ, Locksley RM. PMID: 30201992; PMCID: PMC6202223.
      View in: PubMed   Mentions: 209     Fields:    Translation:AnimalsCells
    17. 940 ILC2s and Type 2 immunity influence hair follicle stem cell proliferation and skin homeostasis. Journal of Investigative Dermatology. 2018 May 1; 138(5):s160. Ricardo-Gonzalez RR, Van Dyken VS, Locksley LR. .
      View in: Publisher Site   Mentions:
    18. 1021 Origin of type 2 innate lymphoid cells in the skin. Journal of Investigative Dermatology. 2018 May 1; 138(5):s173. Lee LJ, Schneider SC, Liang LH, Ricardo-Gonzalez RR, Nussbaum NJ, Smith SL, Villeda VS, Locksley LR. .
      View in: Publisher Site   Mentions:
    19. LB973 Characterization of tissue-resident ILC2 heterogeneity in homeostasis. Journal of Investigative Dermatology. 2017 Oct 1; 137(10):b8. Ricardo-Gonzalez RR, Van Dyken VS, Molofsky MA, Nussbaum NJ, Lee LJ, Locksley LR. .
      View in: Publisher Site   Mentions:
    20. Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation. Cell. 2017 Jun 01; 169(6):1119-1129.e11. Ali N, Zirak B, Rodriguez RS, Pauli ML, Truong HA, Lai K, Ahn R, Corbin K, Lowe MM, Scharschmidt TC, Taravati K, Tan MR, Ricardo-Gonzalez RR, Nosbaum A, Bertolini M, Liao W, Nestle FO, Paus R, Cotsarelis G, Abbas AK, Rosenblum MD. PMID: 28552347; PMCID: PMC5504703.
      View in: PubMed   Mentions: 269     Fields:    Translation:HumansAnimalsCells
    21. Neutrophil-rich subcutaneous fat necrosis of the newborn: A potential mimic of infection. J Am Acad Dermatol. 2016 Jul; 75(1):177-185.e17. Ricardo-Gonzalez RR, Lin JR, Mathes EF, McCalmont TH, Pincus LB. PMID: 27157147.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. A case of Wong-type dermatomyositis with concomitant anti-MDA5 features. J Am Acad Dermatol. 2014 Mar; 70(3):e62-4. Canavan T, Sidorsky T, Doan LT, Ricardo-Gonzalez RR, Shen G, Rosenblum MD. PMID: 24528920.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    23. Plasmacytoid carcinoma of the bladder: a urothelial carcinoma variant with a predilection for intraperitoneal spread. J Urol. 2012 Mar; 187(3):852-5. Ricardo-Gonzalez RR, Nguyen M, Gokden N, Sangoi AR, Presti JC, McKenney JK. PMID: 22245324.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    24. Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. Science. 2011 Apr 08; 332(6026):243-7. Wu D, Molofsky AB, Liang HE, Ricardo-Gonzalez RR, Jouihan HA, Bando JK, Chawla A, Locksley RM. PMID: 21436399; PMCID: PMC3144160.
      View in: PubMed   Mentions: 677     Fields:    Translation:AnimalsCells
    25. IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22617-22. Ricardo-Gonzalez RR, Red Eagle A, Odegaard JI, Jouihan H, Morel CR, Heredia JE, Mukundan L, Wu D, Locksley RM, Chawla A. PMID: 21149710; PMCID: PMC3012500.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    26. PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance. Nat Med. 2009 Nov; 15(11):1266-72. Mukundan L, Odegaard JI, Morel CR, Heredia JE, Mwangi JW, Ricardo-Gonzalez RR, Goh YP, Eagle AR, Dunn SE, Awakuni JU, Nguyen KD, Steinman L, Michie SA, Chawla A. PMID: 19838202; PMCID: PMC2783696.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimalsCells
    27. Regulation of macrophage activation and function by PPARs. Cytokine. 2009 Oct 1; 48(1-2):34. Odegaard OJ, Mukundan ML, Ricardo-Gonzalez RR, Morel MC, Chawla CA. .
      View in: Publisher Site   Mentions:
    28. Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. Cell Metab. 2008 Jun; 7(6):496-507. Odegaard JI, Ricardo-Gonzalez RR, Red Eagle A, Vats D, Morel CR, Goforth MH, Subramanian V, Mukundan L, Ferrante AW, Chawla A. PMID: 18522831; PMCID: PMC2587370.
      View in: PubMed   Mentions: 428     Fields:    Translation:AnimalsCells
    29. A role for GPRx, a novel GPR3/6/12-related G-protein coupled receptor, in the maintenance of meiotic arrest in Xenopus laevis oocytes. Dev Biol. 2008 May 01; 317(1):380-8. Ríos-Cardona D, Ricardo-González RR, Chawla A, Ferrell JE. PMID: 18381211; PMCID: PMC2409273.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    30. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature. 2007 Jun 28; 447(7148):1116-20. Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW, Chawla A. PMID: 17515919; PMCID: PMC2587297.
      View in: PubMed   Mentions: 1039     Fields:    Translation:AnimalsCells
    31. Quantitative expansion of ES cell-derived myeloid progenitors capable of differentiating into macrophages. J Leukoc Biol. 2007 Mar; 81(3):711-9. Odegaard JI, Vats D, Zhang L, Ricardo-Gonzalez R, Smith KL, Sykes DB, Kamps MP, Chawla A. PMID: 17158607; PMCID: PMC1904487.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    32. Clinical benefits in patients with psoriasis after efalizumab therapy: clinical trials versus practice. Cutis. 2004 Sep; 74(3):193-200. Ricardo RR, Rhoa M, Orenberg EK, Li N, Rundle AC, Caro I. PMID: 15499762.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
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