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Gregory Szot, MS

Title(s)Mgr, Islet Transplant Facility, Surgery
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSE, #504
San Francisco CA 94143
PronounsHe/Him/His
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreas. J Immunother Cancer. 2025 Aug 14; 13(8). Quandt Z, Young A, Barlow GL, Smith JA, Kusmartseva I, Dong S, Shapiro MR, Kang JH, Felton JL, Nguyen VQ, Szot G, Hassoun AA, Perdigoto AL, Herold KC, Nolan G, Bollyky PL, Brusko TM, Nakayama M, Cooper S, Anderson MS. PMID: 40813111; PMCID: PMC12359507.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. A Multi-Modal Approach to Islet and Pancreas Transplantation With Calcineurin-Sparing Immunosuppression Maintains Long-Term Insulin Independence in Patients With Type I Diabetes. Transpl Int. 2023; 36:11367. Wisel SA, Posselt AM, Szot GL, Nunez M, Santos-Parker K, Gardner JM, Worner G, Roll GR, Syed S, Kelly Y, Ward C, Tavakol M, Johnson K, Masharani U, Stock PG. PMID: 37359825; PMCID: PMC10285771.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    3. Characterization of human islet function in a convection-driven intravascular bioartificial pancreas. Bioeng Transl Med. 2023 Mar; 8(2):e10444. Santandreu AG, Taheri-Tehrani P, Feinberg B, Torres A, Blaha C, Shaheen R, Moyer J, Wright N, Szot GL, Fissell WH, Vartanian S, Posselt A, Roy S. PMID: 36925691; PMCID: PMC10013798.
      View in: PubMed   Mentions: 4  
    4. Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis. Gut. 2022 09; 71(9):1831-1842. Lee B, Namkoong H, Yang Y, Huang H, Heller D, Szot GL, Davis MM, Husain SZ, Pandol SJ, Bellin MD, Habtezion A. PMID: 34702715; PMCID: PMC9105403.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    5. Superporous agarose scaffolds for encapsulation of adult human islets and human stem-cell-derived β cells for intravascular bioartificial pancreas applications. J Biomed Mater Res A. 2021 12; 109(12):2438-2448. Shaheen R, Gurlin RE, Gologorsky R, Blaha C, Munnangi P, Santandreu A, Torres A, Carnese P, Nair GG, Szot G, Fissell WH, Hebrok M, Roy S. PMID: 34196100.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    6. Arguments against the Requirement of a Biological License Application for Human Pancreatic Islets: The Position Statement of the Islets for US Collaborative Presented during the FDA Advisory Committee Meeting. J Clin Med. 2021 Jun 29; 10(13). Witkowski P, Odorico J, Pyda J, Anteby R, Stratta RJ, Schrope BA, Hardy MA, Buse J, Leventhal JR, Cui W, Hussein S, Niederhaus S, Gaglia J, Desai CS, Wijkstrom M, Kandeel F, Bachul PJ, Becker YT, Wang LJ, Robertson RP, Olaitan OK, Kozlowski T, Abrams PL, Josephson MA, Andreoni KA, Harland RC, Kandaswamy R, Posselt AM, Szot GL, Ricordi C. PMID: 34209541; PMCID: PMC8269003.
      View in: PubMed   Mentions: 2  
    7. Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose control. MAbs. 2021 Jan-Dec; 13(1):1893425. Liu Q, Garg P, Hasdemir B, Wang L, Tuscano E, Sever E, Keane E, Hernandez AGL, Yuan TZ, Kwan E, Lai J, Szot G, Paruthiyil S, Axelrod F, K Sato A. PMID: 33706686; PMCID: PMC7971233.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    8. Pancreas collagen digestion during islet of Langerhans isolation-a prospective study. Transpl Int. 2020 11; 33(11):1516-1528. Meier RPH, Meyer J, Muller YD, Szot GL, Bédat B, Andres A, Massé N, Lablanche S, Puppa G, Bosco D, Berney T. PMID: 32852857.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    9. Distinct immune characteristics distinguish hereditary and idiopathic chronic pancreatitis. J Clin Invest. 2020 05 01; 130(5):2705-2711. Lee B, Adamska JZ, Namkoong H, Bellin MD, Wilhelm J, Szot GL, Louis DM, Davis MM, Pandol SJ, Habtezion A. PMID: 32053120; PMCID: PMC7190911.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    10. Long-term follow-up of beta cell replacement therapy in 10 HIV-infected patients with renal failure secondary to type 1 diabetes mellitus. Am J Transplant. 2020 08; 20(8):2091-2100. Roll GR, Posselt AM, Freise J, Baird J, Syed S, Mo Kang S, Hirose R, Szot GL, Zarinsefat A, Feng S, Worner G, Sarwal M, Stock PG. PMID: 31994295; PMCID: PMC7650842.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Author Correction: Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells. Nat Cell Biol. 2019 06; 21(6):792. Nair GG, Liu JS, Russ HA, Tran S, Saxton MS, Chen R, Juang C, Li ML, Nguyen VQ, Giacometti S, Puri S, Xing Y, Wang Y, Szot GL, Oberholzer J, Bhushan A, Hebrok M. PMID: 30914825.
      View in: PubMed   Mentions: 5     Fields:    
    12. Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells. Nat Cell Biol. 2019 02; 21(2):263-274. Nair GG, Liu JS, Russ HA, Tran S, Saxton MS, Chen R, Juang C, Li ML, Nguyen VQ, Giacometti S, Puri S, Xing Y, Wang Y, Szot GL, Oberholzer J, Bhushan A, Hebrok M. PMID: 30710150; PMCID: PMC6746427.
      View in: PubMed   Mentions: 258     Fields:    Translation:HumansAnimalsCells
    13. Oxygen Perfusion (Persufflation) of Human Pancreata Enhances Insulin Secretion and Attenuates Islet Proinflammatory Signaling. Transplantation. 2019 01; 103(1):160-167. Kelly AC, Smith KE, Purvis WG, Min CG, Weber CS, Cooksey AM, Hasilo C, Paraskevas S, Suszynski TM, Weegman BP, Anderson MJ, Camacho LE, Harland RC, Loudovaris T, Jandova J, Molano DS, Price ND, Georgiev IG, Scott WE, Manas DMD, Shaw JAM, O'Gorman D, Kin T, McCarthy FM, Szot GL, Posselt AM, Stock PG, Karatzas T, Shapiro AMJ, Lynch RM, Limesand SW, Papas KK. PMID: 30095738; PMCID: PMC6371803.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    14. Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant. Stem Cell Reports. 2017 09 12; 9(3):807-819. Faleo G, Russ HA, Wisel S, Parent AV, Nguyen V, Nair GG, Freise JE, Villanueva KE, Szot GL, Hebrok M, Tang Q. PMID: 28803916; PMCID: PMC5599226.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    15. Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428. Diabetes. 2017 09; 66(9):2531. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AMJ. PMID: 28663189; PMCID: PMC5566298.
      View in: PubMed   Mentions:    Fields:    
    16. Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide. CellR4 Repair Replace Regen Reprogram. 2017; 5(3). NIH CIT Consortium Chemistry Manufacturing Controls Monitoring Committee, Ansite J, Balamurugan AN, Barbaro B, Battle J, Brandhorst D, Cano J, Chen X, Deng S, Feddersen D, Friberg A, Gilmore T, Goldstein JS, Holbrook E, Khan A, Kin T, Lei J, Linetsky E, Liu C, Luo X, McElvaney K, Min Z, Moreno J, O'Gorman D, Papas KK, Putz G, Ricordi C, Szot G, Templeton T, Wang L, Wilhelm JJ, Willits J, Wilson T, Zhang X, NIH CIT Consortium, Avila J, Begley B, Cano J, Carpentier S, Holbrook E, Hutchinson J, Larsen CP, Moreno J, Sears M, Turgeon NA, Webster D, Deng S, Lei J, Markmann JF, Bridges ND, Czarniecki CW, Goldstein JS, Putz G, Templeton T, Wilson T, Eggerman TL, Al-Saden P, Battle J, Chen X, Hecyk A, Kissler H, Luo X, Molitch M, Monson N, Stuart E, Wallia A, Wang L, Wang S, Zhang X, Bigam D, Campbell P, Dinyari P, Kin T, Kneteman N, Lyon J, Malcolm A, O'Gorman D, Onderka C, Owen R, Pawlick R, Richer B, Rosichuk S, Sarman D, Schroeder A, Senior PA, Shapiro AMJ, Toth L, Toth V, Zhai W, Johnson K, McElroy J, Posselt AM, Ramos M, Rojas T, Stock PG, Szot G, Barbaro B, Martellotto J, Oberholzer J, Qi M, Wang Y, Bayman L, Chaloner K, Clarke W, Dillon JS, Diltz C, Doelle GC, Ecklund D, Feddersen D, Foster E, Hunsicker LG, Jasperson C, Lafontant DE, McElvaney K, Neill-Hudson T, Nollen D, Qidwai J, Riss H, Schwieger T, Willits J, Yankey J, Alejandro R, Corrales AC, Faradji R, Froud T, Garcia AA, Herrada E, Ichii H, Inverardi L, Kenyon N, Khan A, Linetsky E, Montelongo J, Peixoto E, Peterson K, Ricordi C, Szust J, Wang X, Abdulla MH, Ansite J, Balamurugan AN, Bellin MD, Brandenburg M, Gilmore T, Harmon JV, Hering BJ, Kandaswamy R, Loganathan G, Mueller K, Papas KK, Pedersen J, Wilhelm JJ, Witson J, Dalton-Bakes C, Fu H, Kamoun M, Kearns J, Li Y, Liu C, Luning-Prak E, Luo Y, Markmann E, Min Z, Naji A, Palanjian M, Rickels M, Shlansky-Goldberg R, Vivek K, Ziaie AS, Fernandez L, Kaufman DB, Zitur L, Brandhorst D, Friberg A, Korsgren O. PMID: 30613755; PMCID: PMC6319648.
      View in: PubMed   Mentions:
    17. Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells. Nat Commun. 2017 03 08; 8:14686. Lee J, Snyder ER, Liu Y, Gu X, Wang J, Flowers BM, Kim YJ, Park S, Szot GL, Hruban RH, Longacre TA, Kim SK. PMID: 28272465; PMCID: PMC5344977.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    18. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes. 2016 11; 65(11):3418-3428. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Chen X, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AM, Chen X. PMID: 27465220; PMCID: PMC5079635.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCTClinical Trials
    19. A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation. Cell Transplant. 2016; 25(8):1515-1523. Wang LJ, Kin T, O'Gorman D, Shapiro AMJ, Naziruddin B, Takita M, Levy MF, Posselt AM, Szot GL, Savari O, Barbaro B, McGarrigle J, Yeh CC, Oberholzer J, Lei J, Chen T, Lian M, Markmann JF, Alvarez A, Linetsky E, Ricordi C, Balamurugan AN, Loganathan G, Wilhelm JJ, Hering BJ, Bottino R, Trucco M, Liu C, Min Z, Li Y, Naji A, Fernandez LA, Ziemelis M, Danobeitia JS, Millis JM, Witkowski P. PMID: 26922947; PMCID: PMC5167495.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    20. A Comparative Analysis of the Safety, Efficacy, and Cost of Islet Versus Pancreas Transplantation in Nonuremic Patients With Type 1 Diabetes. Am J Transplant. 2016 Feb; 16(2):518-26. Moassesfar S, Masharani U, Frassetto LA, Szot GL, Tavakol M, Stock PG, Posselt AM. PMID: 26595767; PMCID: PMC5549848.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    21. Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro. EMBO J. 2015 Jul 02; 34(13):1759-72. Russ HA, Parent AV, Ringler JJ, Hennings TG, Nair GG, Shveygert M, Guo T, Puri S, Haataja L, Cirulli V, Blelloch R, Szot GL, Arvan P, Hebrok M. PMID: 25908839; PMCID: PMC4516429.
      View in: PubMed   Mentions: 342     Fields:    Translation:HumansAnimalsCells
    22. Autologous islet transplantation with remote islet isolation after pancreas resection for chronic pancreatitis. JAMA Surg. 2015 Feb; 150(2):118-24. Tai DS, Shen N, Szot GL, Posselt A, Feduska NJ, Habashy A, Clerkin B, Core E, Busuttil RW, Hines OJ, Reber HA, Lipshutz GS. PMID: 25494212.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    23. Tolerance induction and reversal of diabetes in mice transplanted with human embryonic stem cell-derived pancreatic endoderm. Cell Stem Cell. 2015 Feb 05; 16(2):148-57. Szot GL, Yadav M, Lang J, Kroon E, Kerr J, Kadoya K, Brandon EP, Baetge EE, Bour-Jordan H, Bluestone JA. PMID: 25533131.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    24. Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells. Elife. 2013 Nov 19; 2:e00940. Lee J, Sugiyama T, Liu Y, Wang J, Gu X, Lei J, Markmann JF, Miyazaki S, Miyazaki J, Szot GL, Bottino R, Kim SK. PMID: 24252877; PMCID: PMC3826580.
      View in: PubMed   Mentions: 90     Fields:    Translation:Humans
    25. Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation. Am J Transplant. 2013 Nov; 13(11):3010-20. Putnam AL, Safinia N, Medvec A, Laszkowska M, Wray M, Mintz MA, Trotta E, Szot GL, Liu W, Lares A, Lee K, Laing A, Lechler RI, Riley JL, Bluestone JA, Lombardi G, Tang Q. PMID: 24102808; PMCID: PMC4161737.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    26. Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Diabetes. 2013 Aug; 62(8):2870-8. Villalta SA, Lang J, Kubeck S, Kabre B, Szot GL, Calderon B, Wasserfall C, Atkinson MA, Brekken RA, Pullen N, Arch RH, Bluestone JA. PMID: 23835340; PMCID: PMC3717875.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    27. Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade. Transplantation. 2010 Dec 27; 90(12):1595-601. Posselt AM, Szot GL, Frassetto LA, Masharani U, Tavakol M, Amin R, McElroy J, Ramos MD, Kerlan RK, Fong L, Vincenti F, Bluestone JA, Stock PG. PMID: 20978464; PMCID: PMC4296579.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    28. Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab. Am J Transplant. 2010 Aug; 10(8):1870-80. Posselt AM, Bellin MD, Tavakol M, Szot GL, Frassetto LA, Masharani U, Kerlan RK, Fong L, Vincenti FG, Hering BJ, Bluestone JA, Stock PG. PMID: 20659093; PMCID: PMC2911648.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    29. Clinical islet transplantation at the University of California, San Francisco. Clin Transpl. 2010; 235-43. Posselt AM, Szot GL, Frassetto LA, Masharani U, Stock PG. PMID: 21698834.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Successful clinical islet isolation using a GMP-manufactured collagenase and neutral protease. Transplantation. 2009 Sep 27; 88(6):753-6. Szot GL, Lee MR, Tavakol MM, Lang J, Dekovic F, Kerlan RK, Stock PG, Posselt AM. PMID: 19920770; PMCID: PMC2782539.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    31. Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues. J Immunol. 2009 Mar 01; 182(5):2590-600. Melli K, Friedman RS, Martin AE, Finger EB, Miao G, Szot GL, Krummel MF, Tang Q. PMID: 19234153; PMCID: PMC3057894.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    32. Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes. 2009 Mar; 58(3):652-62. Putnam AL, Brusko TM, Lee MR, Liu W, Szot GL, Ghosh T, Atkinson MA, Bluestone JA. PMID: 19074986; PMCID: PMC2646064.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansCells
    33. Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18895-900. Louvet C, Szot GL, Lang J, Lee MR, Martinier N, Bollag G, Zhu S, Weiss A, Bluestone JA. PMID: 19015530; PMCID: PMC2596241.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
    34. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature. 2008 Oct 23; 455(7216):1109-13. Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, Stonebraker AC, Hu C, Wong FS, Szot GL, Bluestone JA, Gordon JI, Chervonsky AV. PMID: 18806780; PMCID: PMC2574766.
      View in: PubMed   Mentions: 994     Fields:    Translation:AnimalsCells
    35. Human albumin preserves islet mass and function better than whole serum during pretransplantation islet culture. Transplant Proc. 2008 Mar; 40(2):384-6. Lee RH, Carter J, Szot GL, Posselt A, Stock P. PMID: 18374076.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    36. Transplantation of pancreatic islets into the kidney capsule of diabetic mice. J Vis Exp. 2007; (9):404. Szot GL, Koudria P, Bluestone JA. PMID: 18989445; PMCID: PMC2566322.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    37. Murine pancreatic islet isolation. J Vis Exp. 2007; (7):255. Szot GL, Koudria P, Bluestone JA. PMID: 18989427; PMCID: PMC2565847.
      View in: PubMed   Mentions: 74     Fields:    Translation:Animals
    38. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med. 2006 Jul 10; 203(7):1701-11. Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, Gottlieb PA, Kapranov P, Gingeras TR, Fazekas de St Groth B, Clayberger C, Soper DM, Ziegler SF, Bluestone JA. PMID: 16818678; PMCID: PMC2118339.
      View in: PubMed   Mentions: 1154     Fields:    Translation:HumansCells
    39. Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. J Clin Invest. 2004 Oct; 114(7):979-87. Bour-Jordan H, Salomon BL, Thompson HL, Szot GL, Bernhard MR, Bluestone JA. PMID: 15467837; PMCID: PMC518661.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    40. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med. 2004 Jun 07; 199(11):1455-65. Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, Ye J, Masteller EL, McDevitt H, Bonyhadi M, Bluestone JA. PMID: 15184499; PMCID: PMC2211775.
      View in: PubMed   Mentions: 534     Fields:    Translation:AnimalsCells
    41. IL-6 protects pancreatic islet beta cells from pro-inflammatory cytokines-induced cell death and functional impairment in vitro and in vivo. Transpl Immunol. 2004 Jun-Jul; 13(1):43-53. Choi SE, Choi KM, Yoon IH, Shin JY, Kim JS, Park WY, Han DJ, Kim SC, Ahn C, Kim JY, Hwang ES, Cha CY, Szot GL, Yoon KH, Park CG. PMID: 15203128.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    42. Targeting and blocking B7 costimulatory molecules on antigen-presenting cells using CTLA4Ig-conjugated liposomes: in vitro characterization and in vivo factors affecting biodistribution. Pharm Res. 2003 Aug; 20(8):1239-48. Park CG, Thiex NW, Lee KM, Szot GL, Bluestone JA, Lee KD. PMID: 12948022.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    43. CD28/B7 regulation of anti-CD3-mediated immunosuppression in vivo. J Immunol. 2003 Feb 01; 170(3):1510-6. Tang Q, Smith JA, Szot GL, Zhou P, Alegre ML, Henriksen KJ, Thompson CB, Bluestone JA. PMID: 12538715.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    44. Inability to induce tolerance through direct antigen presentation. Am J Transplant. 2002 Jul; 2(6):510-9. Rulifson IC, Szot GL, Palmer E, Bluestone JA. PMID: 12118894.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    45. Different mechanisms of cardiac allograft rejection in wildtype and CD28-deficient mice. Am J Transplant. 2001 May; 1(1):38-46. Szot GL, Zhou P, Rulifson I, Wang J, Guo Z, Kim O, Newel KA, Thistlethwaite JR, Bluestone JA, Alegre ML. PMID: 12095035.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    46. Role of STAT6 signaling in the induction and long-term maintenance of tolerance mediated by CTLA4-Ig. Transplant Proc. 2001 Feb-Mar; 33(1-2):214-6. Zhou P, Szot G, Guo Z, Kim O, He G, Wang J, Grusby M, Newell K, Thistlethwaite J, Bluestone J, Alegre M. PMID: 11266784.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    47. Blockade of the CD40 pathway fails to prevent CD8 T cell-mediated intestinal allograft rejection. Transplant Proc. 2001 Feb-Mar; 33(1-2):418-20. Meng L, Guo Z, Kim O, He G, Hart J, Szot GL, Wang J, Pearson TC, Larsen CP, Newell KA. PMID: 11266891.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    48. Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance. J Immunol. 2000 Nov 15; 165(10):5580-7. Zhou P, Szot GL, Guo Z, Kim O, He G, Wang J, Grusby MJ, Newell KA, Thistlethwaite JR, Bluestone JA, Alegre ML. PMID: 11067913.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    49. Absence of host B7 expression is sufficient for long-term murine vascularized heart allograft survival. Transplantation. 2000 Mar 15; 69(5):904-9. Szot GL, Zhou P, Sharpe AH, He G, Kim O, Newell KA, Bluestone JA, Thistlethwaite JR. PMID: 10755548.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    50. Cutting edge: blockade of the CD28/B7 costimulatory pathway inhibits intestinal allograft rejection mediated by CD4+ but not CD8+ T cells. J Immunol. 1999 Sep 01; 163(5):2358-62. Newell KA, He G, Guo Z, Kim O, Szot GL, Rulifson I, Zhou P, Hart J, Thistlethwaite JR, Bluestone JA. PMID: 10452966.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    51. Induction, maintenance, and reversal of streptozotocin-induced insulin-dependent diabetes mellitus in the juvenile cynomolgus monkey (Macaca fascilularis). Transplantation. 1999 Aug 15; 68(3):331-7. Theriault BR, Thistlethwaite JR, Levisetti MG, Wardrip CL, Szot G, Bruce DS, Rilo H, Li X, Gray GS, Bluestone JA, Padrid PA. PMID: 10459535.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    52. The role of CD8 and CD4 T cells in intestinal allograft rejection: a comparison of monoclonal antibody-treated and knockout mice. Transplantation. 1999 Jan 15; 67(1):131-7. He G, Hart J, Kim OS, Szot GL, Siegel CT, Thistlethwaite JR, Newell KA. PMID: 9921809.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    53. Dose and timing of interleukin (IL)-12 and timing and type of total-body irradiation: effects on graft-vs.-host disease inhibition and toxicity of exogenous IL-12 in murine bone marrow transplant recipients. Biol Blood Marrow Transplant. 1999; 5(5):277-84. Sykes M, Pearson DA, Taylor PA, Szot GL, Goldman SJ, Blazar BR. PMID: 10534057.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    54. Separate regulation of peripheral hematopoietic and thymic engraftment. Exp Hematol. 1998 Jun; 26(6):457-65. Sykes M, Szot GL, Swenson K, Pearson DA, Wekerle T. PMID: 9620278.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    55. Interleukin-12 inhibits graft-versus-host disease through an Fas-mediated mechanism associated with alterations in donor T-cell activation and expansion. Blood. 1998 May 01; 91(9):3315-22. Dey BR, Yang YG, Szot GL, Pearson DA, Sykes M. PMID: 9558388.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    56. Interleukin-12 preserves the graft-versus-leukemia effect of allogeneic CD8 T cells while inhibiting CD4-dependent graft-versus-host disease in mice. Blood. 1997 Dec 01; 90(11):4651-60. Yang YG, Sergio JJ, Pearson DA, Szot GL, Shimizu A, Sykes M. PMID: 9373279.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    57. Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation. J Immunol. 1997 Dec 01; 159(11):5187-91. Levisetti MG, Padrid PA, Szot GL, Mittal N, Meehan SM, Wardrip CL, Gray GS, Bruce DS, Thistlethwaite JR, Bluestone JA. PMID: 9548454.
      View in: PubMed   Mentions: 58     Fields:    Translation:Animals
    58. Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning. Nat Med. 1997 Jul; 3(7):783-7. Sykes M, Szot GL, Swenson KA, Pearson DA. PMID: 9212108.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    59. Immune restoration by fetal pig thymus grafts in T cell-depleted, thymectomized mice. J Immunol. 1997 Feb 15; 158(4):1641-9. Zhao Y, Fishman JA, Sergio JJ, Oliveros JL, Pearson DA, Szot GL, Wilkinson RA, Arn JS, Sachs DH, Sykes M. PMID: 9029100.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    60. Inhibition of graft-versus-host disease by interleukin-2 treatment is associated with altered cytokine production by expanded graft-versus-host-reactive CD4+ helper cells. Transplantation. 1995 Sep 15; 60(5):481-90. Wang MG, Szebeni J, Pearson DA, Szot GL, Sykes M. PMID: 7676498.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    61. Interleukin-12 inhibits murine graft-versus-host disease. Blood. 1995 Sep 15; 86(6):2429-38. Sykes M, Szot GL, Nguyen PL, Pearson DA. PMID: 7662991.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    62. IL-2-induced GVHD protection is not inhibited by cyclosporine and is maximal when IL-2 is given over a 25 h period beginning on the day following bone marrow transplantation. Bone Marrow Transplant. 1995 Mar; 15(3):395-9. Sykes M, Pearson DA, Szot GL. PMID: 7599564.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    63. IL-2 inhibits early increases in serum gamma interferon levels associated with graft-versus-host-disease. Transplantation. 1994 Dec 27; 58(12):1385-93. Szebeni J, Wang MG, Pearson DA, Szot GL, Sykes M. PMID: 7809932.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    64. Interleukin-2 inhibits graft-versus-host disease-promoting activity of CD4+ cells while preserving CD4- and CD8-mediated graft-versus-leukemia effects. Blood. 1994 May 01; 83(9):2560-9. Sykes M, Harty MW, Szot GL, Pearson DA. PMID: 7909457.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    65. Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation. J Exp Med. 1993 Jul 01; 178(1):223-9. Sykes M, Harty MW, Karlhofer FM, Pearson DA, Szot G, Yokoyama W. PMID: 8315379; PMCID: PMC2191072.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
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