Robert Blelloch, MD, PhD

InstitutionUniversity of California San Francisco
Address35 Medical Center way
San Fancisco CA 94143
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    Rewiring of the pluripotency enhancer network during early mammalian development
    NIH/NIGMS R01GM122439Sep 7, 2017 - Jul 31, 2021
    Role: Principal Investigator
    Iteratively redefining developmental potential through poised enhancers
    NIH/NIGMS R01GM125089Sep 7, 2017 - Jul 31, 2021
    Role: Principal Investigator
    Emergence of divergent cell cycle programs during mammalian development
    NIH/NICHD R21HD093084Aug 15, 2017 - Jul 31, 2019
    Role: Principal Investigator
    In Vivo Regulated Release and Function of Extracellular Small RNAs
    NIH/NCI U19CA179512Sep 1, 2013 - Aug 31, 2018
    Role: Principal Investigator
    MicroRNA Based Pathway Discovery in Cellular Reprogramming
    NIH/NIGMS R01GM101180May 1, 2012 - Apr 30, 2016
    Role: Principal Investigator
    MiRNAs as prognostic markers for prostate cancer patients on active surveillance
    NIH/NCI R21CA161615Sep 1, 2011 - Aug 31, 2014
    Role: Principal Investigator
    Small RNAs in Stem Cell Differentiation and Neural Development
    NIH/NINDS R01NS057221Jun 15, 2007 - May 31, 2013
    Role: Principal Investigator
    Origins and Biological Consequences of Human Infertility
    NIH/NICHD P50HD055764May 3, 2007 - Mar 31, 2017
    Role: Co-Investigator
    Origins and Biological Consequences of Human Infertility
    NIH/NICHD U54HD055764May 3, 2007 - Mar 31, 2017
    Role: Co-Investigator
    Determinants of Neural &Embryonic Stem Cell Potency
    NIH/NINDS K08NS048118Jul 1, 2005 - Feb 29, 2012
    Role: Principal Investigator
    Predoctoral Training in Developmental Biology
    NIH/NICHD T32HD007470Jul 1, 1994 - Apr 30, 2019
    Role: Principal Investigator
    California National Primate Research Center
    NIH P51RR000169Jun 1, 1975 - Apr 30, 2015
    Role: Co-Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Krishnakumar R, Chen AF, Pantovich MG, Danial M, Parchem RJ, Labosky PA, Blelloch R. FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity. Cell Stem Cell. 2018 Aug 02; 23(2):306-307. PMID: 30075131.
      View in: PubMed
    2. Freimer JW, Hu TJ, Blelloch R. Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells. Elife. 2018 Jul 25; 7. PMID: 30044225.
      View in: PubMed
    3. Chen AF, Liu AJ, Krishnakumar R, Freimer JW, DeVeale B, Blelloch R. GRHL2-Dependent Enhancer Switching Maintains a Pluripotent Stem Cell Transcriptional Subnetwork after Exit from Naive Pluripotency. Cell Stem Cell. 2018 Jun 26. PMID: 30017589.
      View in: PubMed
    4. Freimer JW, Krishnakumar R, Cook MS, Blelloch R. Expression of Alternative Ago2 Isoform Associated with Loss of microRNA-Driven Translational Repression in Mouse Oocytes. Curr Biol. 2018 Jan 22; 28(2):296-302.e3. PMID: 29307557.
      View in: PubMed
    5. Paikari A, D Belair C, Saw D, Blelloch R. The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport. Development. 2017 10 15; 144(20):3731-3743. PMID: 28935707.
      View in: PubMed
    6. Ye J, Jin H, Pankov A, Song JS, Blelloch R. NF45 and NF90/NF110 coordinately regulate ESC pluripotency and differentiation. RNA. 2017 08; 23(8):1270-1284. PMID: 28487382.
      View in: PubMed
    7. Curtis A, Li DJ, DeVeale B, Onishi K, Kim MY, Blelloch R, Laird DJ, Hui EE. Patterning of sharp cellular interfaces with a reconfigurable elastic substrate. Integr Biol (Camb). 2017 01 23; 9(1):50-57. PMID: 28001149.
      View in: PubMed
    8. Gambardella G, Carissimo A, Chen A, Cutillo L, Nowakowski TJ, di Bernardo D, Blelloch R. The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells. Nat Commun. 2017 Jan 19; 8:14126. PMID: 28102192.
      View in: PubMed
    9. D'Aniello C, Habibi E, Cermola F, Paris D, Russo F, Fiorenzano A, Di Napoli G, Melck DJ, Cobellis G, Angelini C, Fico A, Blelloch R, Motta A, Stunnenberg HG, De Cesare D, Patriarca EJ, Minchiotti G. Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum. Stem Cell Reports. 2017 01 10; 8(1):1-10. PMID: 28017658.
      View in: PubMed
    10. Coffre M, Benhamou D, Rieß D, Blumenberg L, Snetkova V, Hines MJ, Chakraborty T, Bajwa S, Jensen K, Chong MMW, Getu L, Silverman GJ, Blelloch R, Littman DR, Calado D, Melamed D, Skok JA, Rajewsky K, Koralov SB. miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation. Cell Rep. 2016 11 22; 17(9):2271-2285. PMID: 27880903.
      View in: PubMed
    11. Tran ND, Kissner M, Subramanyam D, Parchem RJ, Laird DJ, Blelloch R. A miR-372/let-7 Axis Regulates Human Germ Versus Somatic Cell Fates. Stem Cells. 2016 07; 34(7):1985-91. PMID: 27066911.
      View in: PubMed
    12. Krishnakumar R, Chen AF, Pantovich MG, Danial M, Parchem RJ, Labosky PA, Blelloch R. FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity. Cell Stem Cell. 2016 Jan 07; 18(1):104-17. PMID: 26748757; PMCID: PMC4775235 [Available on 01/07/17].
    13. Wang ES, Reyes NA, Melton C, Huskey NE, Momcilovic O, Goga A, Blelloch R, Oakes SA. Fas-Activated Mitochondrial Apoptosis Culls Stalled Embryonic Stem Cells to Promote Differentiation. Curr Biol. 2015 Dec 07; 25(23):3110-8. PMID: 26585277; PMCID: PMC4703423 [Available on 12/07/16].
    14. Patton JG, Franklin JL, Weaver AM, Vickers K, Zhang B, Coffey RJ, Ansel KM, Blelloch R, Goga A, Huang B, L'Etoille N, Raffai RL, Lai CP, Krichevsky AM, Mateescu B, Greiner VJ, Hunter C, Voinnet O, McManus MT. Biogenesis, delivery, and function of extracellular RNA. J Extracell Vesicles. 2015; 4:27494. PMID: 26320939; PMCID: PMC4553266.
    15. Belair CD, Paikari A, Moltzahn F, Shenoy A, Yau C, Dall'Era M, Simko J, Benz C, Blelloch R. DGCR8 is essential for tumor progression following PTEN loss in the prostate. EMBO Rep. 2015 Sep; 16(9):1219-32. PMID: 26206718; PMCID: PMC4576988.
    16. Parchem RJ, Moore N, Fish JL, Parchem JG, Braga TT, Shenoy A, Oldham MC, Rubenstein JL, Schneider RA, Blelloch R. miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015 Aug 04; 12(5):760-73. PMID: 26212322; PMCID: PMC4741278.
    17. Russ HA, Parent AV, Ringler JJ, Hennings TG, Nair GG, Shveygert M, Guo T, Puri S, Haataja L, Cirulli V, Blelloch R, Szot GL, Arvan P, Hebrok M. Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro. EMBO J. 2015 Jul 02; 34(13):1759-72. PMID: 25908839; PMCID: PMC4516429.
    18. Huskey NE, Guo T, Evason KJ, Momcilovic O, Pardo D, Creasman KJ, Judson RL, Blelloch R, Oakes SA, Hebrok M, Goga A. CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation. Stem Cell Reports. 2015 Mar 10; 4(3):374-89. PMID: 25733019; PMCID: PMC4375943.
    19. Shenoy A, Danial M, Blelloch R. Let-7 and miR-125 cooperate to prime progenitors for astrogliogenesis. EMBO J. 2015 May 05; 34(9):1180-94. PMID: 25715649; PMCID: PMC4426479.
    20. Kobayashi T, Papaioannou G, Mirzamohammadi F, Kozhemyakina E, Zhang M, Blelloch R, Chong MW. Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage. Osteoarthritis Cartilage. 2015 Jul; 23(7):1214-20. PMID: 25707934; PMCID: PMC4470813.
    21. Guo WT, Wang XW, Yan YL, Li YP, Yin X, Zhang Q, Melton C, Shenoy A, Reyes NA, Oakes SA, Blelloch R, Wang Y. Suppression of epithelial-mesenchymal transition and apoptotic pathways by miR-294/302 family synergistically blocks let-7-induced silencing of self-renewal in embryonic stem cells. Cell Death Differ. 2015 Jul; 22(7):1158-69. PMID: 25501598; PMCID: PMC4572863.
    22. Ye J, Blelloch R. Regulation of pluripotency by RNA binding proteins. Cell Stem Cell. 2014 Sep 04; 15(3):271-280. PMID: 25192462; PMCID: PMC4372238.
    23. Shenoy A, Blelloch R. Regulation of microRNA function in somatic stem cell proliferation and differentiation. Nat Rev Mol Cell Biol. 2014 Sep; 15(9):565-76. PMID: 25118717; PMCID: PMC4377327.
    24. Wang SY, Shiboski S, Belair CD, Cooperberg MR, Simko JP, Stoppler H, Cowan J, Carroll PR, Blelloch R. miR-19, miR-345, miR-519c-5p serum levels predict adverse pathology in prostate cancer patients eligible for active surveillance. PLoS One. 2014; 9(6):e98597. PMID: 24893170; PMCID: PMC4043973.
    25. Parchem RJ, Ye J, Judson RL, LaRussa MF, Krishnakumar R, Blelloch A, Oldham MC, Blelloch R. Two miRNA clusters reveal alternative paths in late-stage reprogramming. Cell Stem Cell. 2014 May 01; 14(5):617-31. PMID: 24630794; PMCID: PMC4305531.
    26. Judson RL, Greve TS, Parchem RJ, Blelloch R. MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells. Nat Struct Mol Biol. 2013 Oct; 20(10):1227-35. PMID: 24037508; PMCID: PMC3955211.
    27. Krishnakumar R, Blelloch R. Epigenetics of cellular reprogramming. Curr Opin Genet Dev. 2013 Oct; 23(5):548-55. PMID: 23948105; PMCID: PMC4359361.
    28. Greve TS, Judson RL, Blelloch R. microRNA control of mouse and human pluripotent stem cell behavior. Annu Rev Cell Dev Biol. 2013; 29:213-239. PMID: 23875649; PMCID: PMC4793955.
    29. Wang Y, Melton C, Li YP, Shenoy A, Zhang XX, Subramanyam D, Blelloch R. miR-294/miR-302 promotes proliferation, suppresses G1-S restriction point, and inhibits ESC differentiation through separable mechanisms. Cell Rep. 2013 Jul 11; 4(1):99-109. PMID: 23831024; PMCID: PMC3740202.
    30. Jeker LT, Zhou X, Blelloch R, Bluestone JA. DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability. PLoS One. 2013; 8(5):e66282. PMID: 23741528; PMCID: PMC3669207.
    31. Blelloch R, Gutkind JS. Epigenetics, noncoding RNAs, and cell signaling--crossroads in the regulation of cell fate decisions. Curr Opin Cell Biol. 2013 Apr; 25(2):149-51. PMID: 23498659.
      View in: PubMed
    32. Lamouille S, Subramanyam D, Blelloch R, Derynck R. Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. Curr Opin Cell Biol. 2013 Apr; 25(2):200-7. PMID: 23434068; PMCID: PMC4240277.
    33. Cook MS, Blelloch R. Small RNAs in germline development. Curr Top Dev Biol. 2013; 102:159-205. PMID: 23287033.
      View in: PubMed
    34. Seumois G, Vijayanand P, Eisley CJ, Omran N, Kalinke L, North M, Ganesan AP, Simpson LJ, Hunkapiller N, Moltzahn F, Woodruff PG, Fahy JV, Erle DJ, Djukanovic R, Blelloch R, Ansel KM. An integrated nano-scale approach to profile miRNAs in limited clinical samples. Am J Clin Exp Immunol. 2012 Nov 30; 1(2):70-89. PMID: 23304658.
      View in: PubMed
    35. Venere M, Han YG, Bell R, Song JS, Alvarez-Buylla A, Blelloch R. Sox1 marks an activated neural stem/progenitor cell in the hippocampus. Development. 2012 Nov; 139(21):3938-49. PMID: 22992951; PMCID: PMC3472585.
    36. Hsu R, Schofield CM, Dela Cruz CG, Jones-Davis DM, Blelloch R, Ullian EM. Loss of microRNAs in pyramidal neurons leads to specific changes in inhibitory synaptic transmission in the prefrontal cortex. Mol Cell Neurosci. 2012 Jul; 50(3-4):283-92. PMID: 22728723; PMCID: PMC3613865.
    37. Manoli DS, Subramanyam D, Carey C, Sudin E, Van Westerhuyzen JA, Bales KL, Blelloch R, Shah NM. Generation of induced pluripotent stem cells from the prairie vole. PLoS One. 2012; 7(5):e38119. PMID: 22675440; PMCID: PMC3365000.
    38. Barad O, Mann M, Chapnik E, Shenoy A, Blelloch R, Barkai N, Hornstein E. Efficiency and specificity in microRNA biogenesis. Nat Struct Mol Biol. 2012 May 13; 19(6):650-2. PMID: 22580560; PMCID: PMC4378260.
    39. Shenoy A, Blelloch R. microRNA induced transdifferentiation. F1000 Biol Rep. 2012; 4:3. PMID: 22312415; PMCID: PMC3270586.
    40. Chapnik E, Sasson V, Blelloch R, Hornstein E. Dgcr8 controls neural crest cells survival in cardiovascular development. Dev Biol. 2012 Feb 01; 362(1):50-6. PMID: 22138056.
      View in: PubMed
    41. Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R, Ansel KM. MicroRNA-29 regulates T-box transcription factors and interferon-? production in helper T cells. Immunity. 2011 Aug 26; 35(2):169-81. PMID: 21820330; PMCID: PMC3361370.
    42. Moltzahn F, Hunkapiller N, Mir AA, Imbar T, Blelloch R. High throughput microRNA profiling: optimized multiplex qRT-PCR at nanoliter scale on the fluidigm dynamic arrayTM IFCs. J Vis Exp. 2011 Aug 03; (54). PMID: 21847076; PMCID: PMC3211115.
    43. Babiarz JE, Hsu R, Melton C, Thomas M, Ullian EM, Blelloch R. A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing. RNA. 2011 Aug; 17(8):1489-501. PMID: 21712401.
      View in: PubMed
    44. Subramanyam D, Blelloch R. From microRNAs to targets: pathway discovery in cell fate transitions. Curr Opin Genet Dev. 2011 Aug; 21(4):498-503. PMID: 21636265; PMCID: PMC3210035.
    45. Suh N, Blelloch R. Small RNAs in early mammalian development: from gametes to gastrulation. Development. 2011 May; 138(9):1653-61. PMID: 21486922; PMCID: PMC3074443.
    46. Subramanyam D, Lamouille S, Judson RL, Liu JY, Bucay N, Derynck R, Blelloch R. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat Biotechnol. 2011 May; 29(5):443-8. PMID: 21490602; PMCID: PMC3685579.
    47. Schofield CM, Hsu R, Barker AJ, Gertz CC, Blelloch R, Ullian EM. Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex. Neural Dev. 2011 Apr 05; 6:11. PMID: 21466685; PMCID: PMC3082233.
    48. Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M. Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 01; 25(7):755-66. PMID: 21460039; PMCID: PMC3070937.
    49. Wang Y, Blelloch R. Cell cycle regulation by microRNAs in stem cells. Results Probl Cell Differ. 2011; 53:459-72. PMID: 21630156.
      View in: PubMed
    50. Moltzahn F, Olshen AB, Baehner L, Peek A, Fong L, Stöppler H, Simko J, Hilton JF, Carroll P, Blelloch R. Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients. Cancer Res. 2011 Jan 15; 71(2):550-60. PMID: 21098088; PMCID: PMC3022112.
    51. Elefanty AG, Blelloch R, Passegué E, Wernig M, Mummery CL. On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. Cell Stem Cell. 2010 Oct 08; 7(4):443-50. PMID: 20887950.
      View in: PubMed
    52. Swarbrick A, Woods SL, Shaw A, Balakrishnan A, Phua Y, Nguyen A, Chanthery Y, Lim L, Ashton LJ, Judson RL, Huskey N, Blelloch R, Haber M, Norris MD, Lengyel P, Hackett CS, Preiss T, Chetcuti A, Sullivan CS, Marcusson EG, Weiss W, L'Etoile N, Goga A. miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nat Med. 2010 Oct; 16(10):1134-40. PMID: 20871609; PMCID: PMC3019350.
    53. Subramanyam D, Belair CD, Barry-Holson KQ, Lin H, Kogan SC, Passegué E, Blelloch R. PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia. Cancer Res. 2010 Nov 01; 70(21):8792-801. PMID: 20861188; PMCID: PMC3021794.
    54. Bezman NA, Cedars E, Steiner DF, Blelloch R, Hesslein DG, Lanier LL. Distinct requirements of microRNAs in NK cell activation, survival, and function. J Immunol. 2010 Oct 01; 185(7):3835-46. PMID: 20805417; PMCID: PMC2943981.
    55. Song G, Sharma AD, Roll GR, Ng R, Lee AY, Blelloch R, Frandsen NM, Willenbring H. MicroRNAs control hepatocyte proliferation during liver regeneration. Hepatology. 2010 May; 51(5):1735-43. PMID: 20432256; PMCID: PMC3108060.
    56. Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP. Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev. 2010 May 15; 24(10):992-1009. PMID: 20413612; PMCID: PMC2867214.
    57. Suh N, Baehner L, Moltzahn F, Melton C, Shenoy A, Chen J, Blelloch R. MicroRNA function is globally suppressed in mouse oocytes and early embryos. Curr Biol. 2010 Feb 09; 20(3):271-7. PMID: 20116247; PMCID: PMC2872512.
    58. Melton C, Judson RL, Blelloch R. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature. 2010 Feb 04; 463(7281):621-6. PMID: 20054295; PMCID: PMC2894702.
    59. Melton C, Blelloch R. MicroRNA Regulation of Embryonic Stem Cell Self-Renewal and Differentiation. Adv Exp Med Biol. 2010; 695:105-17. PMID: 21222202.
      View in: PubMed
    60. Blelloch R. Journal club. A computational biologist looks at how mRNA length changes during development. Nature. 2009 Nov 12; 462(7270):141. PMID: 19907454.
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    61. Subramanyam D, Blelloch R. Watching reprogramming in real time. Nat Biotechnol. 2009 Nov; 27(11):997-8. PMID: 19898451.
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    62. Shenoy A, Blelloch R. Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8. PLoS One. 2009 Sep 11; 4(9):e6971. PMID: 19759829; PMCID: PMC2736397.
    63. Rao PK, Toyama Y, Chiang HR, Gupta S, Bauer M, Medvid R, Reinhardt F, Liao R, Krieger M, Jaenisch R, Lodish HF, Blelloch R. Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res. 2009 Sep 11; 105(6):585-94. PMID: 19679836; PMCID: PMC2828903.
    64. Wang Y, Blelloch R. Cell cycle regulation by MicroRNAs in embryonic stem cells. Cancer Res. 2009 May 15; 69(10):4093-6. PMID: 19435891; PMCID: PMC2894693.
    65. Judson RL, Babiarz JE, Venere M, Blelloch R. Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat Biotechnol. 2009 May; 27(5):459-61. PMID: 19363475; PMCID: PMC2743930.
    66. Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN. Posttranscriptional crossregulation between Drosha and DGCR8. Cell. 2009 Jan 09; 136(1):75-84. PMID: 19135890; PMCID: PMC2680683.
    67. Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet. 2008 Dec; 40(12):1478-83. PMID: 18978791; PMCID: PMC2630798.
    68. Chaivorapol C, Melton C, Wei G, Yeh RF, Ramalho-Santos M, Blelloch R, Li H. CompMoby: comparative MobyDick for detection of cis-regulatory motifs. BMC Bioinformatics. 2008 Oct 27; 9:455. PMID: 18950538; PMCID: PMC2605473.
    69. Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R. Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev. 2008 Oct 15; 22(20):2773-85. PMID: 18923076; PMCID: PMC2569885.
    70. Blelloch R. Regenerative medicine: short cut to cell replacement. Nature. 2008 Oct 02; 455(7213):604-5. PMID: 18833266.
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    71. Blelloch R, Venere M, Yen J, Ramalho-Santos M. Generation of induced pluripotent stem cells in the absence of drug selection. Cell Stem Cell. 2007 Sep 13; 1(3):245-7. PMID: 18371358; PMCID: PMC2894698.
    72. Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet. 2007 Mar; 39(3):380-5. PMID: 17259983; PMCID: PMC3008549.
    73. Blelloch R, Wang Z, Meissner A, Pollard S, Smith A, Jaenisch R. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem Cells. 2006 Sep; 24(9):2007-13. PMID: 16709876; PMCID: PMC3000431.
    74. Blelloch R, Hochedlinger K, Yamada Y, Brennan C, Kim M, Mintz B, Chin L, Jaenisch R. Nuclear cloning of embryonal carcinoma cells. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):13985-90. PMID: 15306687; PMCID: PMC521109.
    75. Mathies LD, Schvarzstein M, Morphy KM, Blelloch R, Spence AM, Kimble J. TRA-1/GLI controls development of somatic gonadal precursors in C. elegans. Development. 2004 Sep; 131(17):4333-43. PMID: 15294864.
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    76. Hochedlinger K, Blelloch R, Brennan C, Yamada Y, Kim M, Chin L, Jaenisch R. Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev. 2004 Aug 01; 18(15):1875-85. PMID: 15289459; PMCID: PMC517407.
    77. Hochedlinger K, Rideout WM, Kyba M, Daley GQ, Blelloch R, Jaenisch R. Nuclear transplantation, embryonic stem cells and the potential for cell therapy. Hematol J. 2004; 5 Suppl 3:S114-7. PMID: 15190291.
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    78. Jaenisch R, Hochedlinger K, Blelloch R, Yamada Y, Baldwin K, Eggan K. Nuclear cloning, epigenetic reprogramming, and cellular differentiation. Cold Spring Harb Symp Quant Biol. 2004; 69:19-27. PMID: 16117629.
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    79. Blelloch R, Anna-Arriola SS, Gao D, Li Y, Hodgkin J, Kimble J. The gon-1 gene is required for gonadal morphogenesis in Caenorhabditis elegans. Dev Biol. 1999 Dec 01; 216(1):382-93. PMID: 10588887.
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    80. Blelloch R, Newman C, Kimble J. Control of cell migration during Caenorhabditis elegans development. Curr Opin Cell Biol. 1999 Oct; 11(5):608-13. PMID: 10508660.
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    81. Blelloch R, Kimble J. Control of organ shape by a secreted metalloprotease in the nematode Caenorhabditis elegans. Nature. 1999 Jun 10; 399(6736):586-90. PMID: 10376599.
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    82. Roehl H, Bosenberg M, Blelloch R, Kimble J. Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor. EMBO J. 1996 Dec 16; 15(24):7002-12. PMID: 9003776; PMCID: PMC452526.