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Sandy Feng, MD, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentSurgery
Address505 Parnassus Avenue
San Francisco CA 94117
Phone415-353-8725
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityM.D.1990School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Donor-Alloantigen-Reactive Regulatory T Cell Therapy in Liver Transplantation
    NIH/NIAID U01AI110658Jun 1, 2014 - May 31, 2019
    Role: Principal Investigator
    Polyclonal Tregs to Promote Tolerance in Pediatric Liver Transplant Recipients
    NIH U01AI104347Feb 1, 2013 - Jan 31, 2018
    Role: Principal Investigator
    Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients
    NIH U01AI100807Jul 27, 2012 - Jun 30, 2017
    Role: Principal Investigator
    "Donor-Specific Regulatory T Cell Therapy in Liver Transplantation"
    NIH/NIAID R34AI095135Apr 1, 2012 - Mar 31, 2014
    Role: Principal Investigator
    Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients
    NIH U34DK083031Sep 30, 2009 - Mar 31, 2013
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Global Health
    Collapse Websites
    Collapse In The News
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lai JC, Segev DL, McCulloch CE, Covinsky KE, Dodge JL, Feng S. Physical frailty after liver transplantation. Am J Transplant. 2018 Jan 30. PMID: 29380529.
      View in: PubMed
    2. Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S. Reply (to LTE HEP-17-2332). Hepatology. 2018 Jan 29. PMID: 29377206.
      View in: PubMed
    3. Lai JC, Covinsky KE, McCulloch CE, Feng S. The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis. Am J Gastroenterol. 2018 Feb; 113(2):235-242. PMID: 29231189.
      View in: PubMed
    4. Feng S, Bucuvalas J. Tolerance after liver transplantation: Where are we? Liver Transpl. 2017 Dec; 23(12):1601-1614. PMID: 28834221.
      View in: PubMed
    5. Feng S. Living donor liver transplantation in high Model for End-Stage Liver Disease score patients. Liver Transpl. 2017 10; 23(S1):S9-S21. PMID: 28719072.
      View in: PubMed
    6. McLin VA, Allen U, Boyer O, Bucuvalas J, Colledan M, Cuturi MC, d'Antiga L, Debray D, Dezsofi A, Goyet JV, Dhawan A, Durmaz O, Falk C, Feng S, Fischler B, Franchi-Abella S, Frauca E, Ganschow R, Gottschalk S, Hadzic N, Hierro L, Horslen S, Hubscher S, Karam V, Kelly D, Maecker-Kolhoff B, Mazariegos G, McKiernan P, Melk A, Nobili V, Ozgenç F, Reding R, Sciveres M, Sharif K, Socha P, Toso C, Vajro P, Verma A, Wildhaber BE, Baumann U. Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference. J Pediatr Gastroenterol Nutr. 2017 Sep; 65(3):e53-e59. PMID: 28319600.
      View in: PubMed
    7. Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S. Development of a novel frailty index to predict mortality in patients with end-stage liver disease. Hepatology. 2017 08; 66(2):564-574. PMID: 28422306.
      View in: PubMed
    8. Feng S. Optimizing Graft Survival by Pretreatment of the Donor. Clin J Am Soc Nephrol. 2017 03 07; 12(3):388-390. PMID: 28213389.
      View in: PubMed
    9. Chandran S, Feng S. Current status of tolerance in kidney transplantation. Curr Opin Nephrol Hypertens. 2016 11; 25(6):591-601. PMID: 27636772.
      View in: PubMed
    10. Wang CW, Feng S, Covinsky KE, Hayssen H, Zhou LQ, Yeh BM, Lai JC. A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates: Results From the Functional Assessment in Liver Transplantation Study. Transplantation. 2016 Aug; 100(8):1692-8. PMID: 27314169; PMCID: PMC4962324 [Available on 08/01/17].
      View in: PubMed, PubMed Central
    11. Feng S, Demetris AJ, Spain KM, Kanaparthi S, Burrell BE, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK. Five-year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R. Hepatology. 2017 02; 65(2):647-660. PMID: 27302659.
      View in: PubMed
    12. Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge J, Roberts JP, Terrault NA, Feng S. Response to clinical assessments of health status as a potential marker to identify patients who are too sick to undergo transplantation. Liver Int. 2016 Apr; 36(4):611. PMID: 26584013.
      View in: PubMed
    13. Feng S. Spontaneous and induced tolerance for liver transplant recipients. Curr Opin Organ Transplant. 2016 Feb; 21(1):53-8. PMID: 26709575.
      View in: PubMed
    14. Lai JC, Dodge JL, Sen S, Covinsky K, Feng S. Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study. Hepatology. 2016 Feb; 63(2):574-80. PMID: 26517301; PMCID: PMC4718851 [Available on 02/01/17].
      View in: PubMed, PubMed Central
    15. Wang CW, Covinsky KE, Feng S, Hayssen H, Segev DL, Lai JC. Functional impairment in older liver transplantation candidates: From the functional assessment in liver transplantation study. Liver Transpl. 2015 Dec; 21(12):1465-70. PMID: 26359787; PMCID: PMC4715618 [Available on 12/01/16].
      View in: PubMed, PubMed Central
    16. Dumontet E, Danger R, Vagefi PA, Londoño MC, Pallier A, Lozano JJ, Giral M, Degauque N, Soulillou JP, Martínez-Llordella M, Lee H, Latournerie M, Boudjema K, Dulong J, Tarte K, Sanchez-Fueyo A, Feng S, Brouard S, Conchon S. Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients. Liver Int. 2016 Mar; 36(3):401-9. PMID: 26193627.
      View in: PubMed
    17. Dirchwolf M, Dodge JL, Gralla J, Bambha KM, Nydam T, Hung KW, Rosen HR, Feng S, Terrault NA, Biggins SW. The corrected donor age for hepatitis C virus-infected liver transplant recipients. Liver Transpl. 2015 Aug; 21(8):1022-30. PMID: 26074140; PMCID: PMC4809736.
      View in: PubMed, PubMed Central
    18. Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge JL, Roberts JP, Terrault NA, Feng S. Clinician assessments of health status predict mortality in patients with end-stage liver disease awaiting liver transplantation. Liver Int. 2015 Sep; 35(9):2167-73. PMID: 25644788.
      View in: PubMed
    19. Brennan TV, Lunsford KE, Vagefi PA, Bostrom A, Ma M, Feng S. Renal outcomes of simultaneous liver-kidney transplantation compared to liver transplant alone for candidates with renal dysfunction. Clin Transplant. 2015 Jan; 29(1):34-43. PMID: 25328090; PMCID: PMC4800976.
      View in: PubMed, PubMed Central
    20. Sharpton SR, Feng S, Hameed B, Yao F, Lai JC. Combined effects of recipient age and model for end-stage liver disease score on liver transplantation outcomes. Transplantation. 2014 Sep 15; 98(5):557-62. PMID: 24717221; PMCID: PMC4461209.
      View in: PubMed, PubMed Central
    21. Feng S, Lai JC. Expanded criteria donors. Clin Liver Dis. 2014 Aug; 18(3):633-49. PMID: 25017080; PMCID: PMC4809362.
      View in: PubMed, PubMed Central
    22. Vagefi PA, Feng S, Dodge JL, Markmann JF, Roberts JP. Multiple listings as a reflection of geographic disparity in liver transplantation. J Am Coll Surg. 2014 Sep; 219(3):496-504. PMID: 25026876; PMCID: PMC4394199.
      View in: PubMed, PubMed Central
    23. Shores NJ, Dodge JL, Feng S, Terrault NA. Donor Risk Index for African American liver transplant recipients with hepatitis C virus. Hepatology. 2013 Oct; 58(4):1263-9. PMID: 23696235; PMCID: PMC4561529.
      View in: PubMed, PubMed Central
    24. Parekh J, Roll GR, Feng S, Niemann CU, Hirose R. Peri-operative hyperglycemia is associated with delayed graft function in deceased donor renal transplantation. Clin Transplant. 2013 Jul-Aug; 27(4):E424-30. PMID: 23808826.
      View in: PubMed
    25. Lai JC, Feng S, Vittinghoff E, Roberts JP. Offer patterns of nationally placed livers by donation service area. Liver Transpl. 2013 Apr; 19(4):404-10. PMID: 23447450; PMCID: PMC3689315.
      View in: PubMed, PubMed Central
    26. Lai JC, Feng S, Roberts JP. An examination of liver offers to candidates on the liver transplant wait-list. Gastroenterology. 2012 Nov; 143(5):1261-5. PMID: 22841780; PMCID: PMC3480537.
      View in: PubMed, PubMed Central
    27. Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP, Rosenthal P, Alonso EM, Philogene MC, Ikle D, Poole KM, Bridges ND, Turka LA, Tchao NK. Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants. JAMA. 2012 Jan 18; 307(3):283-93. PMID: 22253395.
      View in: PubMed
    28. Singh KM, Phung YT, Kohla MS, Lan BY, Chan S, Suen DL, Murad S, Rheault S, Davidson P, Evans J, Singh M, Dohil S, Osorio RW, Wakil AE, Page K, Feng S, Cooper SL. KIR genotypic diversity can track ancestries in heterogeneous populations: a potential confounder for disease association studies. Immunogenetics. 2012 Feb; 64(2):97-109. PMID: 21898189; PMCID: PMC4143378.
      View in: PubMed, PubMed Central
    29. Levine MH, Parekh J, Feng S, Freise C. Kidney transplant performed after liver transplant: a single center experience. Clin Transplant. 2011 Nov-Dec; 25(6):915-20. PMID: 21077957.
      View in: PubMed
    30. Gelb B, Feng S. Management of the liver transplant patient. Expert Rev Gastroenterol Hepatol. 2009 Dec; 3(6):631-47. PMID: 19929584.
      View in: PubMed
    31. Kuo A, Tan V, Lan B, Khalili M, Feng S, Roberts JP, Terrault NA. Long-term histological effects of preemptive antiviral therapy in liver transplant recipients with hepatitis C virus infection. Liver Transpl. 2008 Oct; 14(10):1491-7. PMID: 18825708.
      View in: PubMed
    32. Feng S. Long-term management of immunosuppression after pediatric liver transplantation: is minimization or withdrawal desirable or possible or both? Curr Opin Organ Transplant. 2008 Oct; 13(5):506-12. PMID: 19060534.
      View in: PubMed
    33. Yao FY, Kerlan RK, Hirose R, Davern TJ, Bass NM, Feng S, Peters M, Terrault N, Freise CE, Ascher NL, Roberts JP. Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysis. Hepatology. 2008 Sep; 48(3):819-27. PMID: 18688876; PMCID: PMC4142499.
      View in: PubMed, PubMed Central
    34. Feng S. Steatotic livers for liver transplantation--life-saving but at a cost. Nat Clin Pract Gastroenterol Hepatol. 2008 Jul; 5(7):360-1. PMID: 18493235.
      View in: PubMed
    35. Roayaie K, Feng S. Allocation policy for hepatocellular carcinoma in the MELD era: room for improvement? Liver Transpl. 2007 Nov; 13(11 Suppl 2):S36-43. PMID: 17969067.
      View in: PubMed
    36. Gilmore AS, Helderman JH, Ricci JF, Ryskina KL, Feng S, Kang N, Legorreta AP. Linking the US transplant registry to administrative claims data: expanding the potential of transplant research. Med Care. 2007 Jun; 45(6):529-36. PMID: 17515780.
      View in: PubMed
    37. Sekine S, Gutiérrez PJ, Lan BY, Feng S, Hebrok M. Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. Hepatology. 2007 Feb; 45(2):361-8. PMID: 17256747.
      View in: PubMed
    38. Biggins SW, Feng S. In a MELD-based economy, how can we fight off inflation? Liver Transpl. 2007 Jan; 13(1):2-4. PMID: 17192889.
      View in: PubMed
    39. Brennan TV, Bostrom A, Feng S. Optimizing living donor kidney graft function by donor-recipient pair selection. Transplantation. 2006 Sep 15; 82(5):651-6. PMID: 16969288.
      View in: PubMed
    40. Rafaelian O, Coakley FV, Qayyum A, Breiman RS, Yeh BM, Joe BN, Westphalen AC, Feng S. Magnetic resonance imaging of hepatocellular carcinoma mimicking focal nodular hyperplasia: a potential pitfall in patients with cirrhosis? J Comput Assist Tomogr. 2006 Sep-Oct; 30(5):796-9. PMID: 16954932.
      View in: PubMed
    41. Merion RM, Goodrich NP, Feng S. How can we define expanded criteria for liver donors? J Hepatol. 2006 Oct; 45(4):484-8. PMID: 16905221.
      View in: PubMed
    42. Fuller TF, Hoff U, Rose F, Linde Y, Freise CE, Dragun D, Feng S. Effect of mycophenolate mofetil on rat kidney grafts with prolonged cold preservation. Kidney Int. 2006 Aug; 70(3):570-7. PMID: 16788694.
      View in: PubMed
    43. Sekine S, Lan BY, Bedolli M, Feng S, Hebrok M. Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice. Hepatology. 2006 Apr; 43(4):817-25. PMID: 16557553.
      View in: PubMed
    44. Feng S, Si M, Taranto SE, McBride MA, Mudge C, Stritzel S, Roberts JP, Rosenthal P. Trends over a decade of pediatric liver transplantation in the United States. Liver Transpl. 2006 Apr; 12(4):578-84. PMID: 16555314.
      View in: PubMed
    45. Fuller TF, Brennan TV, Feng S, Kang SM, Stock PG, Freise CE. End stage polycystic kidney disease: indications and timing of native nephrectomy relative to kidney transplantation. J Urol. 2005 Dec; 174(6):2284-8. PMID: 16280813.
      View in: PubMed
    46. Yao FY, Hirose R, LaBerge JM, Davern TJ, Bass NM, Kerlan RK, Merriman R, Feng S, Freise CE, Ascher NL, Roberts JP. A prospective study on downstaging of hepatocellular carcinoma prior to liver transplantation. Liver Transpl. 2005 Dec; 11(12):1505-14. PMID: 16315294.
      View in: PubMed
    47. Feng S. Selecting livers for transplantation: can beggars be choosers? Nat Clin Pract Gastroenterol Hepatol. 2005 Nov; 2(11):496-7. PMID: 16355138.
      View in: PubMed
    48. Carter JT, Chan S, Roberts JP, Feng S. Expanded criteria donor kidney allocation: marked decrease in cold ischemia and delayed graft function at a single center. Am J Transplant. 2005 Nov; 5(11):2745-53. PMID: 16212636.
      View in: PubMed
    49. Magee JC, Feng S. PELD: working well, but only half of the time? Am J Transplant. 2005 Aug; 5(8):1785-6. PMID: 15996222.
      View in: PubMed
    50. Carter JT, Freise CE, McTaggart RA, Mahanty HD, Kang SM, Chan SH, Feng S, Roberts JP, Posselt AM. Laparoscopic procurement of kidneys with multiple renal arteries is associated with increased ureteral complications in the recipient. Am J Transplant. 2005 Jun; 5(6):1312-8. PMID: 15888035.
      View in: PubMed
    51. McTaggart RA, Tomlanovich SJ, Feng S. Impact of sirolimus on early graft function after deceased-donor kidney transplantation. Transplantation. 2005 Apr 27; 79(8):991; author reply 991-2. PMID: 15849562.
      View in: PubMed
    52. Feng S, Roberts J. An older liver in the hand, or a (possibly) younger liver in the bush? Am J Transplant. 2005 Mar; 5(3):425-7. PMID: 15707395.
      View in: PubMed
    53. Feng S, Humar A, Pomfret E, Fishbein T, Gaber O. Surgical challenges in transplantation: the Fourth Annual American Society of Transplant Surgeons' State-of-the-Art Winter Symposium. Am J Transplant. 2005 Mar; 5(3):428-35. PMID: 15707396.
      View in: PubMed
    54. Lipshutz GS, Mahanty H, Feng S, Hirose R, Stock PG, Kang SM, Posselt AM, Freise CE. BKV in simultaneous pancreas-kidney transplant recipients: a leading cause of renal graft loss in first 2 years post-transplant. Am J Transplant. 2005 Feb; 5(2):366-73. PMID: 15643997.
      View in: PubMed
    55. Fernandes JR, Duvivier-Kali VF, Keegan M, Hollister-Lock J, Omer A, Su S, Bonner-Weir S, Feng S, Lee JS, Mulligan RC, Weir GC. Transplantation of islets transduced with CTLA4-Ig and TGFbeta using adenovirus and lentivirus vectors. Transpl Immunol. 2004 Nov; 13(3):191-200. PMID: 15381202.
      View in: PubMed
    56. Fuller TF, Feng S, Brennan TV, Tomlanovich S, Bostrom A, Freise CE. Increased rejection in living unrelated versus living related kidney transplants does not affect short-term function and survival. Transplantation. 2004 Oct 15; 78(7):1030-5. PMID: 15480170.
      View in: PubMed
    57. Beer S, Zetterberg A, Ihrie RA, McTaggart RA, Yang Q, Bradon N, Arvanitis C, Attardi LD, Feng S, Ruebner B, Cardiff RD, Felsher DW. Developmental context determines latency of MYC-induced tumorigenesis. PLoS Biol. 2004 Nov; 2(11):e332. PMID: 15455033; PMCID: PMC519000.
      View in: PubMed, PubMed Central
    58. McTaggart RA, Tomlanovich S, Bostrom A, Roberts JP, Feng S. Comparison of outcomes after delayed graft function: sirolimus-based versus other calcineurin-inhibitor sparing induction immunosuppression regimens. Transplantation. 2004 Aug 15; 78(3):475-80. PMID: 15316379.
      View in: PubMed
    59. McTaggart RA, Terrault NA, Vardanian AJ, Bostrom A, Feng S. Hepatitis C etiology of liver disease is strongly associated with early acute rejection following liver transplantation. Liver Transpl. 2004 Aug; 10(8):975-85. PMID: 15390322.
      View in: PubMed
    60. Takemoto SK, Zeevi A, Feng S, Colvin RB, Jordan S, Kobashigawa J, Kupiec-Weglinski J, Matas A, Montgomery RA, Nickerson P, Platt JL, Rabb H, Thistlethwaite R, Tyan D, Delmonico FL. National conference to assess antibody-mediated rejection in solid organ transplantation. Am J Transplant. 2004 Jul; 4(7):1033-41. PMID: 15196059.
      View in: PubMed
    61. Brennan TV, Freise CE, Fuller TF, Bostrom A, Tomlanovich SJ, Feng S. Early graft function after living donor kidney transplantation predicts rejection but not outcomes. Am J Transplant. 2004 Jun; 4(6):971-9. PMID: 15147432.
      View in: PubMed
    62. McTaggart RA, Feng S. An uncomfortable silence em leader while we all search for a better reporter gene in adult stem cell biology. Hepatology. 2004 Apr; 39(4):1143-6. PMID: 15057919.
      View in: PubMed
    63. Collignon FP, Holland EC, Feng S. Organ donors with malignant gliomas: an update. Am J Transplant. 2004 Jan; 4(1):15-21. PMID: 14678030.
      View in: PubMed
    64. Fuller TF, Freise CE, Serkova N, Niemann CU, Olson JL, Feng S. Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury. Transplantation. 2003 Dec 15; 76(11):1594-9. PMID: 14702530.
      View in: PubMed
    65. Feng S, Buell JF, Chari RS, DiMaio JM, Hanto DW. Tumors and transplantation: The 2003 Third Annual ASTS State-of-the-Art Winter Symposium. Am J Transplant. 2003 Dec; 3(12):1481-7. PMID: 14629278.
      View in: PubMed
    66. Lipshutz GS, Baxter-Lowe LA, Nguyen T, Jones KD, Ascher NL, Feng S. Death from donor-transmitted malignancy despite emergency liver retransplantation. Liver Transpl. 2003 Oct; 9(10):1102-7. PMID: 14526407.
      View in: PubMed
    67. Freise CE, Kang SM, Feng S, Hirose R, Stock P. Excellent short-term results with steroid-free maintenance immunosuppression in low-risk simultaneous pancreas-kidney transplantation. Arch Surg. 2003 Oct; 138(10):1121-5; discussion 1125-6. PMID: 14557130.
      View in: PubMed
    68. Fuller TF, Kang SM, Hirose R, Feng S, Stock PG, Freise CE. Management of lymphoceles after renal transplantation: laparoscopic versus open drainage. J Urol. 2003 Jun; 169(6):2022-5. PMID: 12771709.
      View in: PubMed
    69. McTaggart RA, Gottlieb D, Brooks J, Bacchetti P, Roberts JP, Tomlanovich S, Feng S. Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation. Am J Transplant. 2003 Apr; 3(4):416-23. PMID: 12694063.
      View in: PubMed
    70. Metzger RA, Delmonico FL, Feng S, Port FK, Wynn JJ, Merion RM. Expanded criteria donors for kidney transplantation. Am J Transplant. 2003; 3 Suppl 4:114-25. PMID: 12694055.
      View in: PubMed
    71. Feng S, Buell JF, Cherikh WS, Deng MC, Hanto DW, Kauffman HM, Leichtman AB, Lorber MI, Maters RG, McBride MA, Metzger RA, Nolte FS, O'Connor KJ, Roth D, Terrault NA, Henry ML. Organ donors with positive viral serology or malignancy: risk of disease transmission by transplantation. Transplantation. 2002 Dec 27; 74(12):1657-63. PMID: 12499875.
      View in: PubMed
    72. Rosengard BR, Feng S, Alfrey EJ, Zaroff JG, Emond JC, Henry ML, Garrity ER, Roberts JP, Wynn JJ, Metzger RA, Freeman RB, Port FK, Merion RM, Love RB, Busuttil RW, Delmonico FL. Report of the Crystal City meeting to maximize the use of organs recovered from the cadaver donor. Am J Transplant. 2002 Sep; 2(8):701-11. PMID: 12243491.
      View in: PubMed
    73. Chang GJ, Liu T, Feng S, Bedolli M, O'rourke RW, Schmidt G, Roberts JP, Stock PG. Targeted gene therapy with CD40Ig to induce long-term acceptance of liver allografts. Surgery. 2002 Aug; 132(2):149-56. PMID: 12219005.
      View in: PubMed
    74. Feng S, Holland EC. HIV-1 tat trans-activation requires the loop sequence within tar. Nature. 1988 Jul 14; 334(6178):165-7. PMID: 3386755.
      View in: PubMed
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