Audrey Parent • UCSF Profiles

Audrey Parent, PhD

Title(s)	Associate Professor, Diabetes Center
School	School of Medicine
Address	513 Parnassus Ave, HSW, #1116 San Francisco CA 94143
Phone	415-514-2111
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Overview

Websites

Parent Lab

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency. Nature. 2023 Nov 08. Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, Perez Lorenzo M, Rackaityte E, Rinchai D, Zhang P, Bizien L, Hancioglu G, Ghillani-Dalbin P, Charuel JL, Philippot Q, Gueye MS, Maglorius Renkilaraj MRL, Ogishi M, Soudée C, Migaud M, Rozenberg F, Momenilandi M, Riller Q, Imberti L, Delmonte OM, Müller G, Keller B, Orrego J, Franco Gallego WA, Rubin T, Emiroglu M, Parvaneh N, Eriksson D, Aranda-Guillen M, Berrios DI, Vong L, Katelaris CH, Mustillo P, Raedler J, Bohlen J, Bengi Celik J, Astudillo C, Winter S, NF-?B Consortium, COVID Human Genetic Effort, McLean C, Guffroy A, DeRisi JL, Yu D, Miller C, Feng Y, Guichard A, Béziat V, Bustamante J, Pan-Hammarström Q, Zhang Y, Rosen LB, Holland SM, Bosticardo M, Kenney H, Castagnoli R, Slade CA, Boztug K, Mahlaoui N, Latour S, Abraham RS, Lougaris V, Hauck F, Sediva A, Atschekzei F, Sogkas G, Poli MC, Slatter MA, Palterer B, Keller MD, Pinzon-Charry A, Sullivan A, Droney L, Suan D, Wong M, Kane A, Hu H, Ma C, Grombiríková H, Ciznar P, Dalal I, Aladjidi N, Hie M, Lazaro E, Franco J, Keles S, Malphettes M, Pasquet M, Maccari ME, Meinhardt A, Ikinciogullari A, Shahrooei M, Celmeli F, Frosk P, Goodnow CC, Gray PE, Belot A, Kuehn HS, Rosenzweig SD, Miyara M, Licciardi F, Servettaz A, Barlogis V, Le Guenno G, Herrmann VM, Kuijpers T, Ducoux G, Sarrot-Reynauld F, Schuetz C, Cunningham-Rundles C, Rieux-Laucat F, Tangye SG, Sobacchi C, Doffinger R, Warnatz K, Grimbacher B, Fieschi C, Berteloot L, Bryant VL, Trouillet Assant S, Su H, Neven B, Abel L, Zhang Q, Boisson B, Cobat A, Jouanguy E, Kampe O, Bastard P, Roifman CM, Landegren N, Notarangelo LD, Anderson MS, Casanova JL, Puel A. PMID: 37938781.

View in: PubMed Mentions: Fields:
Sci Science
Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance. Sci Immunol. 2023 Oct 27; 8(88):eabq3109. Sin JH, Sucharov J, Kashyap S, Wang Y, Proekt I, Liu X, Parent AV, Gupta A, Kastner P, Chan S, Gardner JM, Ntranos V, Miller CN, Anderson MS, Schjerven H, Waterfield MR. PMID: 37889983.

View in: PubMed Mentions: Fields:
All Allergy and Immunology
Translation:Humans Animals
Redox Regulation of m 6 A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes. bioRxiv. 2023 Feb 16. De Jesus DF, Zhang Z, Brown NK, Li X, Gaffrey MJ, Kahraman S, Wei J, Hu J, Basile G, Xiao L, Rana TM, Mathews C, Powers AC, Atkinson MA, Eizirik DL, Dhe-Paganon S, Parent AV, Qian WJ, He C, Kulkarni RN. PMID: 36824909; PMCID: PMC9948953.

View in: PubMed Mentions:
Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy. Diabetes. 2023 01 01; 72(1):59-70. Mandel-Brehm C, Vazquez SE, Liverman C, Cheng M, Quandt Z, Kung AF, Parent A, Miao B, Disse E, Cugnet-Anceau C, Dalle S, Orlova E, Frolova E, Alba D, Michels A, Oftedal BE, Lionakis MS, Husebye ES, Agarwal AK, Li X, Zhu C, Li Q, Oral E, Brown R, Anderson MS, Garg A, DeRisi JL. PMID: 35709010; PMCID: PMC9797316.

View in: PubMed Mentions: 1 Fields:
End Endocrinology
Translation:Humans Animals
Stem cell-based multi-tissue platforms to model human autoimmune diabetes. Mol Metab. 2022 12; 66:101610. Leavens KF, Alvarez-Dominguez JR, Vo LT, Russ HA, Parent AV. PMID: 36209784; PMCID: PMC9587366.

View in: PubMed Mentions: 3 Fields:
Met Metabolism
Translation:Humans Cells
Development of a scalable method to isolate subsets of stem cell-derived pancreatic islet cells. Stem Cell Reports. 2022 04 12; 17(4):979-992. Parent AV, Ashe S, Nair GG, Li ML, Chavez J, Liu JS, Zhong Y, Streeter PR, Hebrok M. PMID: 35245441; PMCID: PMC9023773.

View in: PubMed Mentions: 11 Fields:
Cel Cell Biology
Translation:Humans Cells
Modeling human T1D-associated autoimmune processes. Mol Metab. 2022 02; 56:101417. Khosravi-Maharlooei M, Madley R, Borsotti C, Ferreira LMR, Sharp RC, Brehm MA, Greiner DL, Parent AV, Anderson MS, Sykes M, Creusot RJ. PMID: 34902607; PMCID: PMC8739876.

View in: PubMed Mentions: 6 Fields:
Met Metabolism
Translation:Humans Animals Cells
Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection. Cell Rep. 2021 08 17; 36(7):109538. Parent AV, Faleo G, Chavez J, Saxton M, Berrios DI, Kerper NR, Tang Q, Hebrok M. PMID: 34407395.

View in: PubMed Mentions: 19 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Humans Animals Cells
From type 1 diabetes biology to therapy: The Human Islet Research Network. Mol Metab. 2021 12; 54:101283. Kaddis JS, Rouse L, Parent AV, Saunders DC, Shalev A, Stabler CL, Stoffers DA, Wagner BK, Niland JC. PMID: 34224917; PMCID: PMC8711046.

View in: PubMed Mentions: 1 Fields:
Met Metabolism
Translation:Humans Cells
Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla. Nat Commun. 2021 02 17; 12(1):1096. Bautista JL, Cramer NT, Miller CN, Chavez J, Berrios DI, Byrnes LE, Germino J, Ntranos V, Sneddon JB, Burt TD, Gardner JM, Ye CJ, Anderson MS, Parent AV. PMID: 33597545; PMCID: PMC7889611.

View in: PubMed Mentions: 52 Fields:
Bio Biology Sci Science
Translation:Humans Animals Cells
High-resolution epitope mapping of anti-Hu and anti-Yo autoimmunity by programmable phage display. Brain Commun. 2020; 2(2):fcaa059. O'Donovan B, Mandel-Brehm C, Vazquez SE, Liu J, Parent AV, Anderson MS, Kassimatis T, Zekeridou A, Hauser SL, Pittock SJ, Chow E, Wilson MR, DeRisi JL. PMID: 32954318; PMCID: PMC7425417.

View in: PubMed Mentions: 21
Landscape of stimulation-responsive chromatin across diverse human immune cells. Nat Genet. 2019 10; 51(10):1494-1505. Calderon D, Nguyen MLT, Mezger A, Kathiria A, Müller F, Nguyen V, Lescano N, Wu B, Trombetta J, Ribado JV, Knowles DA, Gao Z, Blaeschke F, Parent AV, Burt TD, Anderson MS, Criswell LA, Greenleaf WJ, Marson A, Pritchard JK. PMID: 31570894; PMCID: PMC6858557.

View in: PubMed Mentions: 102 Fields:
Gen Genetics
Translation:Humans Cells
Supporting Survival of Transplanted Stem-Cell-Derived Insulin-Producing Cells in an Encapsulation Device Augmented with Controlled Release of Amino Acids. Adv Biosyst. 2019 Sep; 3(9). Chendke GS, Faleo G, Juang C, Parent AV, Bernards DA, Hebrok M, Tang Q, Desai TA. PMID: 31633004; PMCID: PMC6800235.

View in: PubMed Mentions: 5 Fields:
Bio Biomedical Engineering Bio Biotechnology
Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature. 2018 07; 559(7715):627-631. Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS. PMID: 30022164; PMCID: PMC6062473.

View in: PubMed Mentions: 134 Fields:
Sci Science
Translation:Humans Animals Cells
Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant. Stem Cell Reports. 2017 09 12; 9(3):807-819. Faleo G, Russ HA, Wisel S, Parent AV, Nguyen V, Nair GG, Freise JE, Villanueva KE, Szot GL, Hebrok M, Tang Q. PMID: 28803916; PMCID: PMC5599226.

View in: PubMed Mentions: 23 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Nanoporous Immunoprotective Device for Stem-Cell-Derived β-Cell Replacement Therapy. ACS Nano. 2017 08 22; 11(8):7747-7757. Chang R, Faleo G, Russ HA, Parent AV, Elledge SK, Bernards DA, Allen JL, Villanueva K, Hebrok M, Tang Q, Desai TA. PMID: 28763191; PMCID: PMC5667644.

View in: PubMed Mentions: 29 Fields:
Nan Nanotechnology
Translation:Animals
Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro. EMBO J. 2015 Jul 02; 34(13):1759-72. Russ HA, Parent AV, Ringler JJ, Hennings TG, Nair GG, Shveygert M, Guo T, Puri S, Haataja L, Cirulli V, Blelloch R, Szot GL, Arvan P, Hebrok M. PMID: 25908839; PMCID: PMC4516429.

View in: PubMed Mentions: 289 Fields:
Bio Biotechnology Mol Molecular Biology
Translation:Humans Animals Cells
Generation of functional thymic epithelium from human embryonic stem cells that supports host T cell development. Cell Stem Cell. 2013 Aug 01; 13(2):219-29. Parent AV, Russ HA, Khan IS, LaFlam TN, Metzger TC, Anderson MS, Hebrok M. PMID: 23684540; PMCID: PMC3869399.

View in: PubMed Mentions: 80 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):17010-5. Landsman L, Parent A, Hebrok M. PMID: 21969560; PMCID: PMC3193206.

View in: PubMed Mentions: 38 Fields:
Sci Science
Translation:Animals Cells
WDR36 acts as a scaffold protein tethering a G-protein-coupled receptor, Gαq and phospholipase Cβ in a signalling complex. J Cell Sci. 2011 Oct 01; 124(Pt 19):3292-304. Cartier A, Parent A, Labrecque P, Laroche G, Parent JL. PMID: 21940795.

View in: PubMed Mentions: 14 Fields:
Cel Cell Biology
Translation:Humans Cells
ANKRD13C acts as a molecular chaperone for G protein-coupled receptors. J Biol Chem. 2010 Dec 24; 285(52):40838-51. Parent A, Roy SJ, Iorio-Morin C, Lépine MC, Labrecque P, Gallant MA, Slipetz D, Parent JL. PMID: 20959461; PMCID: PMC3003385.

View in: PubMed Mentions: 11 Fields:
Bio Biochemistry
Translation:Humans Cells
Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: identification of a recycling motif. Eur J Pharmacol. 2010 Mar 25; 630(1-3):10-8. Roy SJ, Parent A, Gallant MA, de Brum-Fernandes AJ, Stanková J, Parent JL. PMID: 20035740.

View in: PubMed Mentions: 7 Fields:
Pha Pharmacology
Translation:Humans Cells
Rab11 regulates the recycling of the beta2-adrenergic receptor through a direct interaction. Biochem J. 2009 Feb 15; 418(1):163-72. Parent A, Hamelin E, Germain P, Parent JL. PMID: 18983266.

View in: PubMed Mentions: 41 Fields:
Bio Biochemistry
Translation:Humans Cells
RACK1 regulates the cell surface expression of the G protein-coupled receptor for thromboxane A(2). Traffic. 2008 Mar; 9(3):394-407. Parent A, Laroche G, Hamelin E, Parent JL. PMID: 18088317.

View in: PubMed Mentions: 21 Fields:
Phy Physiology
Translation:Humans Cells
Peroxiredoxin-4 interacts with and regulates the thromboxane A(2) receptor. FEBS Lett. 2007 Aug 07; 581(20):3863-8. Giguère P, Turcotte ME, Hamelin E, Parent A, Brisson J, Laroche G, Labrecque P, Dupuis G, Parent JL. PMID: 17644091.

View in: PubMed Mentions: 21 Fields:
Bio Biochemistry
Translation:Humans Cells