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Salomeh Keyhani, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    University of California, Davis, Davis, California MD06/1999Medicine
    Johns Hopkins Hospital, Baltimore, Maryland06/2002Internal Medicine Residency
    Johns Hopkins School of Medicine, Baltimore, Maryland06/2004Robert Wood Johnson Clinical Scholar
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MarylandMPH06/2004Public Health

    Collapse Overview 
    Collapse Overview
    Dr. Keyhani is a general internist and a health services researcher. She has experience in retrospective cohort study designs, use of natural language processing to construct cohorts, and use of advanced statistical techniques for observational research. She is currently leading multiple NIH funded cohort studies and has used natural language processing for either cohort construction or data extraction in all studies. Areas of focus include the cardiovascular health effects of marijuana use, the management of carotid and predictors of 30-day readmission.

    She also has an active research program in health care quality and health policy. Her quality of care research to date has focused on examining the underuse and overuse of medical procedures, comparing receipt of appropriate therapy in different systems of care (e.g. Medicare versus Veterans Health Administration) and examining system factors that contribute to improved quality. More recently her quality of care work has focused more specifically on stroke therapies such as carotid endarterectomy and thrombolytic therapy. Her policy research has largely focused on areas important to health care reform and factors that may contribute to inefficiency and the use of inappropriate care in the US health care system. She has surveyed physicians on their views towards national guidelines, comparative effectiveness research, defensive medicine and conflicts of interest in medicine.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Keyhani S, Abraham A, Cohen B, Vali M, Yoo SR, Dollinger C, Steigerwald S. Development of a Cannabis Assessment Tool (CAT-1) to measure current and lifetime marijuana use among older Veterans. BMJ Open. 2020 Jan 14; 10(1):e034274. PMID: 31941767.
      View in: PubMed
    2. Steigerwald S, Cohen BE, Vali M, Hasin D, Cerda M, Keyhani S. Differences in Opinions About Marijuana Use and Prevalence of Use by State Legalization Status. J Addict Med. 2019 Dec 04. PMID: 31821192.
      View in: PubMed
    3. Stacey Steigerwald, Beth E. Cohen, Marzieh Vali, Deborah Hasin, Magdalena Cerda, Salomeh Keyhani. Differences in Opinions About Marijuana Use and Prevalence of Use by State Legalization Status. Journal of Addiction Medicine. 2019 Dec 1; 1.
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    4. Wray CM, Vali M, Byers A, Keyhani S. Examining the Association of Social Determinants of Health with Missed Clinic Visits in Patients with Heart Failure in the Veterans Health Administration. J Gen Intern Med. 2019 Nov 11. PMID: 31713034.
      View in: PubMed
    5. Ghasemiesfe M, Barrow B, Leonard S, Keyhani S, Korenstein D. Association Between Marijuana Use and Risk of Cancer: A Systematic Review and Meta-analysis. JAMA Netw Open. 2019 Nov 01; 2(11):e1916318. PMID: 31774524.
      View in: PubMed
    6. Ishida JH, Zhang AJ, Steigerwald S, Cohen BE, Vali M, Keyhani S. Sources of Information and Beliefs About the Health Effects of Marijuana. J Gen Intern Med. 2019 Oct 21. PMID: 31637640.
      View in: PubMed
    7. Tummalapalli SL, Keyhani S. Trends in Preventative Health Services for Veterans with Military Coverage Compared to Non-Military Coverage. J Gen Intern Med. 2019 Oct 16. PMID: 31621048.
      View in: PubMed
    8. Ishida JH, Wong PO, Cohen BE, Vali M, Steigerwald S, Keyhani S. Substitution of marijuana for opioids in a national survey of US adults. PLoS One. 2019; 14(10):e0222577. PMID: 31584957.
      View in: PubMed
    9. Ghasemiesfe M, Ravi D, Casino T, Korenstein D, Keyhani S. Acute Cardiovascular Effects of Marijuana Use. J Gen Intern Med. 2019 Aug 13. PMID: 31407239.
      View in: PubMed
    10. Tummalapalli SL, Powe NR, Keyhani S. Trends in Quality of Care for Patients with CKD in the United States. Clin J Am Soc Nephrol. 2019 Aug 07; 14(8):1142-1150. PMID: 31296503.
      View in: PubMed
    11. Wray CM, Vali M, Abraham A, Zhang A, Walter LC, Keyhani S. Validation of Administrative Measures of Social and Behavioral Risk in Veterans Affairs Medical Records. J Gen Intern Med. 2019 Jun; 34(6):796-798. PMID: 30604115.
      View in: PubMed
    12. Tummalapalli SL, Leonard S, Estrella MM, Keyhani S. The Effect of Medicaid Expansion on Self-Reported Kidney Disease. Clin J Am Soc Nephrol. 2019 Aug 07; 14(8):1238-1240. PMID: 31097453.
      View in: PubMed
    13. Wray CM, Vali M, Walter LC, Lopez L, Austin PC, Byers A, Keyhani S. Examining the Utility of 30-day Readmission Rates and Hospital Profiling in the Veterans Health Administration. J Hosp Med. 2019 May; 14(5):266-271. PMID: 30794141.
      View in: PubMed
    14. S. Keyhani, E. Madden, E.M. Cheng, D.M. Bravata, E. Halm, P.C. Austin. Risk Prediction Tools to Improve Patient Selection for Carotid Endarterectomy Among Patients With Asymptomatic Carotid Stenosis. Journal of Vascular Surgery. 2019 May 1; 69(5):1645-1646.
      View in: Publisher Site
    15. Conway M, Keyhani S, Christensen L, South BR, Vali M, Walter LC, Mowery DL, Abdelrahman S, Chapman WW. Moonstone: a novel natural language processing system for inferring social risk from clinical narratives. J Biomed Semantics. 2019 04 11; 10(1):6. PMID: 30975223.
      View in: PubMed
    16. Wray CM, Lopez L, Keyhani S. "Comparing VA and Non-VA Care Quality". J Gen Intern Med. 2019 Apr; 34(4):485. PMID: 30543019.
      View in: PubMed
    17. Keyhani S, Madden E, Cheng EM, Bravata DM, Halm E, Austin PC, Ghasemiesfe M, Abraham AS, Zhang AJ, Johanning JM. Risk Prediction Tools to Improve Patient Selection for Carotid Endarterectomy Among Patients With Asymptomatic Carotid Stenosis. JAMA Surg. 2019 Apr 01; 154(4):336-344. PMID: 30624562.
      View in: PubMed
    18. Yoo SR, Dollinger C, Vali M, Steigerwald S, Cohen BE, Ishida JH, Keyhani S. Perceptions of the Comparative Safety of Different Forms of Marijuana Use Among the Adult US Population. J Gen Intern Med. 2019 Apr; 34(4):504-506. PMID: 30535750.
      View in: PubMed
    19. Korenstein D, Chimonas S, Barrow B, Keyhani S, Troy A, Lipitz-Snyderman A. Development of a Conceptual Map of Negative Consequences for Patients of Overuse of Medical Tests and Treatments. JAMA Intern Med. 2018 10 01; 178(10):1401-1407. PMID: 30105371.
      View in: PubMed
    20. Steigerwald S, Wong PO, Khorasani A, Keyhani S. The Form and Content of Cannabis Products in the United States. J Gen Intern Med. 2018 09; 33(9):1426-1428. PMID: 29770952.
      View in: PubMed
    21. Abraham A, Zhang AJ, Ahn R, Woodbridge A, Korenstein D, Keyhani S. Media Content Analysis of Marijuana's Health Effects in News Coverage. J Gen Intern Med. 2018 09; 33(9):1438-1440. PMID: 29845473.
      View in: PubMed
    22. Steigerwald S, Wong PO, Cohen BE, Ishida JH, Vali M, Madden E, Keyhani S. Smoking, Vaping, and Use of Edibles and Other Forms of Marijuana Among U.S. Adults. Ann Intern Med. 2018 12 18; 169(12):890-892. PMID: 30167665.
      View in: PubMed
    23. Keyhani S, Steigerwald S, Ishida J, Vali M, Cerdá M, Hasin D, Dollinger C, Yoo SR, Cohen BE. Risks and Benefits of Marijuana Use: A National Survey of U.S. Adults. Ann Intern Med. 2018 09 04; 169(5):282-290. PMID: 30039154.
      View in: PubMed
    24. Ghasemiesfe M, Ravi D, Vali M, Korenstein D, Arjomandi M, Frank J, Austin PC, Keyhani S. Marijuana Use, Respiratory Symptoms, and Pulmonary Function: A Systematic Review and Meta-analysis. Ann Intern Med. 2018 07 17; 169(2):106-115. PMID: 29971337.
      View in: PubMed
    25. Abraham A, Ahn R, Woodbridge A, Madden E, Keyhani S, Korenstein D. What Constitutes an Independent Statistical Analysis? J Gen Intern Med. 2018 06; 33(6):786-788. PMID: 29549498.
      View in: PubMed
    26. Keyhani S, Vali M, Cohen B, Woodbridge A, Arenson M, Eilkhani E, Aivadyan C, Hasin D. A search algorithm for identifying likely users and non-users of marijuana from the free text of the electronic medical record. PLoS One. 2018; 13(3):e0193706. PMID: 29509775.
      View in: PubMed
    27. Woodbridge A, Abraham A, Ahn R, Saba S, Korenstein D, Madden E, Keyhani S. A Cross-Sectional Analysis of Spin in Randomized Controlled Trials. J Gen Intern Med. 2018 03; 33(3):247-248. PMID: 29313224.
      View in: PubMed
    28. Jones CW, Misemer BS, Platts-Mills TF, Ahn R, Woodbridge A, Abraham A, Saba S, Korenstein D, Madden E, Keyhani S. Primary outcome switching among drug trials with and without principal investigator financial ties to industry: a cross-sectional study. BMJ Open. 2018 02 08; 8(2):e019831. PMID: 29439079.
      View in: PubMed
    29. Ravi D, Ghasemiesfe M, Korenstein D, Cascino T, Keyhani S. Associations Between Marijuana Use and Cardiovascular Risk Factors and Outcomes: A Systematic Review. Ann Intern Med. 2018 02 06; 168(3):187-194. PMID: 29357394.
      View in: PubMed
    30. Cascino T, Vali M, Redberg R, Bravata DM, Boscardin J, Eilkhani E, Keyhani S. Guideline concordance of new statin prescriptions: who got a statin? Am J Manag Care. 2017 Sep; 23(9):528-533. PMID: 29087155.
      View in: PubMed
    31. Baxi SS, Kale M, Keyhani S, Roman BR, Yang A, Derosa AP, Korenstein D. Overuse of Health Care Services in the Management of Cancer: A Systematic Review. Med Care. 2017 07; 55(7):723-733. PMID: 28498197.
      View in: PubMed
    32. Ahn R, Woodbridge A, Abraham A, Saba S, Korenstein D, Madden E, Boscardin WJ, Keyhani S. Financial ties of principal investigators and randomized controlled trial outcomes: cross sectional study. BMJ. 2017 Jan 17; 356:i6770. PMID: 28096109.
      View in: PubMed
    33. Flynn S, Hebert P, Korenstein D, Ryan M, Jordan WB, Keyhani S. Leveraging Social Media to Promote Evidence-Based Continuing Medical Education. PLoS One. 2017; 12(1):e0168962. PMID: 28060854.
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    34. Shrujal S. Baxi, Minal Kale, Benjamin R Roman, Annie Yang, Antonio Derosa, Azalea Kim, Salomeh Keyhani, Deborah Korenstein. Systematic review of overuse in oncology. Journal of Clinical Oncology. 2016 May 20; 34(15_suppl):e18257-e18257.
      View in: Publisher Site
    35. Mowery DL, Chapman BE, Conway M, South BR, Madden E, Keyhani S, Chapman WW. Extracting a stroke phenotype risk factor from Veteran Health Administration clinical reports: an information content analysis. J Biomed Semantics. 2016; 7:26. PMID: 27175226.
      View in: PubMed
    36. Keyhani S, Cheng EM, Naseri A, Halm EA, Williams LS, Johanning J, Madden E, Rofagha S, Woodbridge A, Abraham A, Ahn R, Saba S, Eilkhani E, Hebert P, Bravata DM. Common Reasons That Asymptomatic Patients Who Are 65 Years and Older Receive Carotid Imaging. JAMA Intern Med. 2016 05 01; 176(5):626-33. PMID: 27088224.
      View in: PubMed
    37. Korenstein D, Duan K, Diaz MJ, Ahn R, Keyhani S. Do Health Care Delivery System Reforms Improve Value? The Jury Is Still Out. Med Care. 2016 Jan; 54(1):55-66. PMID: 26492216.
      View in: PubMed
    38. Keyhani S, Myers LJ, Cheng E, Hebert P, Williams LS, Bravata DM. Effect of clinical and social risk factors on hospital profiling for stroke readmission: a cohort study. Ann Intern Med. 2014 Dec 02; 161(11):775-84. PMID: 25437405.
      View in: PubMed
    39. Keyhani S, Cheng E, Ofner S, Williams L, Bravata D. The underuse of carotid interventions in veterans with symptomatic carotid stenosis. Am J Manag Care. 2014 Jul 01; 20(7):e250-6. PMID: 25295544.
      View in: PubMed
    40. Blum AB, Egorova NN, Sosunov EA, Gelijns AC, DuPree E, Moskowitz AJ, Federman AD, Ascheim DD, Keyhani S. Impact of socioeconomic status measures on hospital profiling in New York City. Circ Cardiovasc Qual Outcomes. 2014 May; 7(3):391-7. PMID: 24823956.
      View in: PubMed
    41. Bishop TF, Press MJ, Keyhani S, Pincus HA. Acceptance of insurance by psychiatrists and the implications for access to mental health care. JAMA Psychiatry. 2014 Feb; 71(2):176-81. PMID: 24337499.
      View in: PubMed
    42. Kale MS, Federman AD, Keyhani S. Accurately estimating cervical cancer screening overuse among older women--reply. JAMA Intern Med. 2013 Jul 08; 173(13):1266-7. PMID: 23836274.
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    43. Keyhani S, Falk R, Howell EA, Bishop T, Korenstein D. Overuse and systems of care: a systematic review. Med Care. 2013 Jun; 51(6):503-8. PMID: 23552430.
      View in: PubMed
    44. Kale MS, Bishop TF, Federman AD, Keyhani S. Trends in the overuse of ambulatory health care services in the United States. JAMA Intern Med. 2013 Jan 28; 173(2):142-8. PMID: 23266529.
      View in: PubMed
    45. Cheng EM, Bravata DM, El-Saden S, Vassar SD, Ofner S, Williams LS, Keyhani S. Carotid artery stenosis: wide variability in reporting formats--a review of 127 Veterans Affairs medical centers. Radiology. 2013 Jan; 266(1):289-94. PMID: 23143022.
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    46. Legare K, Bakshi S, Keyhani S, Howell EA. Availability of over-the-counter emergency contraception in 2 disparate New York City neighborhoods. Am J Public Health. 2012 Nov; 102(11):e45-7. PMID: 22994248.
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    47. Keyhani S, Cheng E, Arling G, Li X, Myers L, Ofner S, Williams LS, Phipps M, Ordin D, Bravata DM. Does the inclusion of stroke severity in a 30-day mortality model change standardized mortality rates at Veterans Affairs hospitals? Circ Cardiovasc Qual Outcomes. 2012 Jul 01; 5(4):508-13. PMID: 22787062.
      View in: PubMed
    48. Cheng EM, Keyhani S, Ofner S, Williams LS, Hebert PL, Ordin DL, Bravata DM. Lower use of carotid artery imaging at minority-serving hospitals. Neurology. 2012 Jul 10; 79(2):138-44. PMID: 22700815.
      View in: PubMed
    49. E. Cheng, S. Keyhani, S. Ofner, L. Williams, D. Bravata. Standardized Reporting Is Needed To Describe Results of Carotid Artery Imaging (P01.032). Neurology. 2012 Apr 23; 78(Meeting Abstracts 1):p01.032-p01.032.
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    50. Keyhani S, Falk R, Bishop T, Howell E, Korenstein D. The relationship between geographic variations and overuse of healthcare services: a systematic review. Med Care. 2012 Mar; 50(3):257-61. PMID: 22329997.
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    51. Korenstein D, Falk R, Howell EA, Bishop T, Keyhani S. Overuse of health care services in the United States: an understudied problem. Arch Intern Med. 2012 Jan 23; 172(2):171-8. PMID: 22271125.
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    52. Keyhani S, Arling G, Williams LS, Ross JS, Ordin DL, Myers J, Tyndall G, Vogel B, Bravata DM. The use and misuse of thrombolytic therapy within the Veterans Health Administration. Med Care. 2012 Jan; 50(1):66-73. PMID: 22182924.
      View in: PubMed
    53. Arling G, Reeves M, Ross J, Williams LS, Keyhani S, Chumbler N, Phipps MS, Roumie C, Myers LJ, Salanitro AH, Ordin DL, Myers J, Bravata DM. Estimating and reporting on the quality of inpatient stroke care by Veterans Health Administration Medical Centers. Circ Cardiovasc Qual Outcomes. 2012 Jan; 5(1):44-51. PMID: 22147888.
      View in: PubMed
    54. Neuman J, Korenstein D, Ross JS, Keyhani S. Prevalence of financial conflicts of interest among panel members producing clinical practice guidelines in Canada and United States: cross sectional study. BMJ. 2011 Oct 11; 343:d5621. PMID: 21990257.
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    55. Kale MS, Bishop TF, Federman AD, Keyhani S. "Top 5" lists top $5 billion. Arch Intern Med. 2011 Nov 14; 171(20):1856-8. PMID: 21965814.
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    56. Korenstein D, Keyhani S, Mendelson A, Ross JS. Adherence of pharmaceutical advertisements in medical journals to FDA guidelines and content for safe prescribing. PLoS One. 2011; 6(8):e23336. PMID: 21858076.
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    57. Ross JS, Arling G, Ofner S, Roumie CL, Keyhani S, Williams LS, Ordin DL, Bravata DM. Correlation of inpatient and outpatient measures of stroke care quality within veterans health administration hospitals. Stroke. 2011 Aug; 42(8):2269-75. PMID: 21719771.
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    58. Bishop TF, Federman AD, Keyhani S. Declines in physician acceptance of medicare and private coverage. Arch Intern Med. 2011 Jun 27; 171(12):1117-9. PMID: 21709115.
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    59. Federman AD, Keyhani S. Physicians' participation in the Physicians' Quality Reporting Initiative and their perceptions of its impact on quality of care. Health Policy. 2011 Oct; 102(2-3):229-34. PMID: 21628079.
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    60. Keyhani S, Kim A, Mann M, Korenstein D. A new independent authority is needed to issue National Health Care guidelines. Health Aff (Millwood). 2011 Feb; 30(2):256-65. PMID: 21289347.
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    61. Federman AD, Woodward M, Keyhani S. Physicians' opinions about reforming reimbursement: results of a national survey. Arch Intern Med. 2010 Oct 25; 170(19):1735-42. PMID: 20975020.
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    62. Keyhani S, Woodward M, Federman AD. Physician views on the use of comparative effectiveness research: a national survey. Ann Intern Med. 2010 Oct 19; 153(8):551-2. PMID: 20956718.
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    63. Federman AD, Penrod JD, Livote E, Hebert P, Keyhani S, Doucette J, Siu AL. Development of and recovery from difficulty with activities of daily living: an analysis of national data. J Aging Health. 2010 Dec; 22(8):1081-98. PMID: 20660637.
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    64. Bishop TF, Federman AD, Keyhani S. Physicians' views on defensive medicine: a national survey. Arch Intern Med. 2010 Jun 28; 170(12):1081-3. PMID: 20585077.
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    65. Keyhani S, Federman A. Health care reform and the AMA. N Engl J Med. 2010 Jun 10; 362(23):2230-2. PMID: 20558379.
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    66. Korenstein D, Keyhani S, Ross JS. Physician attitudes toward industry: a view across the specialties. Arch Surg. 2010 Jun; 145(6):570-7. PMID: 20566978.
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    67. Keyhani S, Wang S, Hebert P, Carpenter D, Anderson G. US pharmaceutical innovation in an international context. Am J Public Health. 2010 Jun; 100(6):1075-80. PMID: 20403883.
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    68. Ross JS, Keyhani S, Korenstein D. Appropriateness of collaborations between industry and the medical profession: physicians' perceptions. Am J Med. 2009 Oct; 122(10):955-60. PMID: 19786162.
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    69. Keyhani S, Federman A. Doctors on coverage--physicians' views on a new public insurance option and Medicare expansion. N Engl J Med. 2009 Oct 01; 361(14):e24. PMID: 19752465.
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    70. Keyhani S, Federman A. Fact or fiction: the need for independent pharmaceutical policy research. J Gen Intern Med. 2009 May; 24(5):692-4. PMID: 19343457.
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    71. Federman AD, Safran DG, Keyhani S, Cole H, Halm EA, Siu AL. Awareness of pharmaceutical cost-assistance programs among inner-city seniors. Am J Geriatr Pharmacother. 2009 Apr; 7(2):117-29. PMID: 19447364.
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    72. Keyhani S, Siu AL. The underuse of overuse research. Health Serv Res. 2008 Dec; 43(6):1923-30. PMID: 19166411.
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    73. Keyhani S, Hebert PL, Ross JS, Federman A, Zhu CW, Siu AL. Electronic health record components and the quality of care. Med Care. 2008 Dec; 46(12):1267-72. PMID: 19300317.
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    74. Keyhani S, Kleinman LC, Rothschild M, Bernstein JM, Anderson R, Chassin M. Overuse of tympanostomy tubes in New York metropolitan area: evidence from five hospital cohort. BMJ. 2008 Oct 03; 337:a1607. PMID: 18835846.
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    75. Federman AD, Safran DG, Keyhani S, Siu AL, Halm EA. Low levels of awareness of pharmaceutical cost-assistance programs among inner-city seniors. JAMA. 2008 Sep 24; 300(12):1412-4. PMID: 18812531.
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    76. Ross JS, Keyhani S, Keenan PS, Bernheim SM, Penrod JD, Boockvar KS, Federman AD, Krumholz HM, Siu AL. Use of recommended ambulatory care services: is the Veterans Affairs quality gap narrowing? Arch Intern Med. 2008 May 12; 168(9):950-8. PMID: 18474759.
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    77. Ross JS, Keyhani S, Keenan PS, Bernheim SM, Penrod JD, Boockvar KS, Krumholz HM, Siu AL. Dual use of Veterans Affairs services and use of recommended ambulatory care. Med Care. 2008 Mar; 46(3):309-16. PMID: 18388846.
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    78. Keyhani S, Scobie JV, Hebert PL, McLaughlin MA. Gender disparities in blood pressure control and cardiovascular care in a national sample of ambulatory care visits. Hypertension. 2008 Apr; 51(4):1149-55. PMID: 18259013.
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    79. Keyhani S, Kleinman LC, Rothschild M, Bernstein JM, Anderson R, Simon M, Chassin M. Clinical characteristics of New York City children who received tympanostomy tubes in 2002. Pediatrics. 2008 Jan; 121(1):e24-33. PMID: 18166541.
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    80. Keyhani S, Ross JS. The cost of pharmaceutical innovation to patients. Expert Opin Drug Discov. 2007 Nov; 2(11):1431-4. PMID: 23484595.
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    81. Keyhani S, Ross JS, Hebert P, Dellenbaugh C, Penrod JD, Siu AL. Use of preventive care by elderly male veterans receiving care through the Veterans Health Administration, Medicare fee-for-service, and Medicare HMO plans. Am J Public Health. 2007 Dec; 97(12):2179-85. PMID: 17971544.
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    82. Salomeh Keyhani. Time: The Authors Respond. Health Affairs. 2006 Jul 1; 25(4):1188-1188.
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    83. Keyhani S, Diener-West M, Powe N. Are development times for pharmaceuticals increasing or decreasing? Health Aff (Millwood). 2006 Mar-Apr; 25(2):461-8. PMID: 16522587.
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    84. Broumand V, Keyhani S, Broumand B. The importance of origins? Science. 2005 Sep 09; 309(5741):1673-5; author reply 1673-5. PMID: 16156011.
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    85. Keyhani S, Diener-West M, Powe N. Do drug prices reflect development time and government investment? Med Care. 2005 Aug; 43(8):753-62. PMID: 16034288.
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    86. Anderson GF, Shea DG, Hussey PS, Keyhani S, Zephyrin L. Doughnut holes and price controls. Health Aff (Millwood). 2004 Jul-Dec; Suppl Web Exclusives:W4-396-404. PMID: 15451953.
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