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Lorenzo Pasquini, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentNeurology
Address675 Nelson Rising Lane
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    Technische Universität München, MunichPhD09/2016Neuroimaging of dementia
    Brain Institute, Natal (Brazil)Visiting scholar03/2016Neuroimaging
    King's College London, LondonVisiting scholar06/2015Epidemiology
    Ludwig Maximilians Universität, MunichMS09/2015Public Health
    Université Paris Sud, ParisErasmus student09/2008Neuroscience
    Ludwig Maximilians Universität, MunichDiploma09/2011Biology
    Collapse Awards and Honors
    Society of Neuroscience2017  - 2017Minisymposium
    Big Data Neuroscience 20172017  - 2017Travel Fellowsip
    AAIC2016  - 2016Travel Fellowship
    German Academic Foundation2014  - 2016PhD Fellowship

    Collapse Overview 
    Collapse Overview
    I have joined the Seeley lab in November 2016 as a postdoctoral fellow. My background is in Neuroscience and Public Health. I obtained my PhD from the Technical University of Munich, where I investigated large-scale brain network dysfunctions in Alzheimer’s disease, with a specific focus on multimodal neuroimaging and intrinsic activity of the medial temporal lobes. Among other projects, I have collaborated with the Psychiatry Department of King’s College London on a project investigating neurological determinants of dementia in low and middle income countries (10/66 Research Group), and with the Brain Institute in Natal on a fMRI project investigating the effects of the psychedelic substance Ayahuasca on brain activity. My main interests are to investigate the link between neuropathology and neuroimaging, and to develop subject tailored neuroimaging biomarkers for frontotemporal dementia.


    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Göttler J, Preibisch C, Riederer I, Pasquini L, Alexopoulos P, Bohn KP, Yakushev I, Beller E, Kaczmarz S, Zimmer C, Grimmer T, Drzezga A, Sorg C. Reduced blood oxygenation level dependent connectivity is related to hypoperfusion in Alzheimer's disease. J Cereb Blood Flow Metab. 2018 Jan 01; 271678X18759182. PMID: 29431005.
      View in: PubMed
    2. Pasquini L, Benson G, Grothe MJ, Utz L, Myers NE, Yakushev I, Grimmer T, Scherr M, Sorg C. Individual Correspondence of Amyloid-ß and Intrinsic Connectivity in the Posterior Default Mode Network Across Stages of Alzheimer's Disease. J Alzheimers Dis. 2017; 58(3):763-773. PMID: 28482640.
      View in: PubMed
    3. Nuttall R, Pasquini L, Scherr M, Sorg C. Degradation in intrinsic connectivity networks across the Alzheimer's disease spectrum. Alzheimers Dement (Amst). 2016; 5:35-42. PMID: 28054026.
      View in: PubMed
    4. Ortner M, Pasquini L, Barat M, Alexopoulos P, Grimmer T, Förster S, Diehl-Schmid J, Kurz A, Förstl H, Zimmer C, Wohlschläger A, Sorg C, Peters H. Progressively Disrupted Intrinsic Functional Connectivity of Basolateral Amygdala in Very Early Alzheimer's Disease. Front Neurol. 2016; 7:132. PMID: 27698649.
      View in: PubMed
    5. Pasquini L, Scherr M, Tahmasian M, Myers NE, Ortner M, Kurz A, Förstl H, Zimmer C, Grimmer T, Akhrif A, Wohlschläger AM, Riedl V, Sorg C. Increased Intrinsic Activity of Medial-Temporal Lobe Subregions is Associated with Decreased Cortical Thickness of Medial-Parietal Areas in Patients with Alzheimer's Disease Dementia. J Alzheimers Dis. 2016; 51(1):313-26. PMID: 26836175.
      View in: PubMed
    6. Tahmasian M, Pasquini L, Scherr M, Meng C, Förster S, Mulej Bratec S, Shi K, Yakushev I, Schwaiger M, Grimmer T, Diehl-Schmid J, Riedl V, Sorg C, Drzezga A. The lower hippocampus global connectivity, the higher its local metabolism in Alzheimer disease. Neurology. 2015 May 12; 84(19):1956-63. PMID: 25878180.
      View in: PubMed
    7. Pasquini L, Scherr M, Tahmasian M, Meng C, Myers NE, Ortner M, Mühlau M, Kurz A, Förstl H, Zimmer C, Grimmer T, Wohlschläger AM, Riedl V, Sorg C. Link between hippocampus' raised local and eased global intrinsic connectivity in AD. Alzheimers Dement. 2015 May; 11(5):475-84. PMID: 25043909.
      View in: PubMed
    8. Koch K, Myers NE, Göttler J, Pasquini L, Grimmer T, Förster S, Manoliu A, Neitzel J, Kurz A, Förstl H, Riedl V, Wohlschläger AM, Drzezga A, Sorg C. Disrupted Intrinsic Networks Link Amyloid-ß Pathology and Impaired Cognition in Prodromal Alzheimer's Disease. Cereb Cortex. 2015 Dec; 25(12):4678-88. PMID: 24996404; PMCID: PMC4635914 [Available on 12/01/16].
    9. Pasquini L, Tonch A, Plant C, Zherdin A, Ortner M, Kurz A, Förstl H, Zimmer C, Grimmer T, Wohlschäger A, Riedl V, Sorg C. Intrinsic brain activity of cognitively normal older persons resembles more that of patients both with and at risk for Alzheimer's disease than that of healthy younger persons. Brain Connect. 2014 Jun; 4(5):323-36. PMID: 24689864; PMCID: PMC4064725.
    10. Myers N, Pasquini L, Göttler J, Grimmer T, Koch K, Ortner M, Neitzel J, Mühlau M, Förster S, Kurz A, Förstl H, Zimmer C, Wohlschläger AM, Riedl V, Drzezga A, Sorg C. Within-patient correspondence of amyloid-ß and intrinsic network connectivity in Alzheimer's disease. Brain. 2014 Jul; 137(Pt 7):2052-64. PMID: 24771519; PMCID: PMC4065018.
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