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Srilaxmi Nerella, MS

Title(s)Specialist, Medicine
SchoolSchool of Medicine
Address513 Parnassus Avenue HSE, #301
San Francisco CA 94143
PronounsShe/Her/Hers
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    Bioinformatics specialist with 14 years of experience in genomic data analysis, next-generation sequencing (NGS), and computational biology. Skilled in developing and applying bioinformatics pipelines for high-throughput sequencing data, genome annotation, biomarker discovery, and functional genomics analysis. Experienced in working with large-scale transcriptomic and genomic datasets, including bulk RNA-seq, single-cell RNA-seq, and other sequencing-based platforms. Also experienced in Drupal-based web development for scientific website design, content organization, and research data presentation. Interested in applying machine learning, statistical analysis, and high-performance computing approaches to genomics and biomedical research, with the goal of generating meaningful insights from complex biological datasets and supporting collaborative research.

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    Collapse Education and Training
    The University of Texas at AustinPostgraduate program01/2026 Artificial Intelligence and Machine Learning: Business Applications
    The University of Texas at El Paso (UTEP), USA Master of Science 2010Bioinformatics
    Osmania University College for Women (OUCW), IndiaMaster of Science2007Biotechnology
    Osmania University College for Women (OUCW), IndiaBachelor of Science 2005Genetics

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    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. HuR Regulates GATA3-Driven Type 2 Inflammation in CD4? T cells and ILC2 in Airway Inflammation. bioRxiv. 2026 May 14. Atasoy U, Fattahi F, Yaekle L, Holden J, Tepper B, Hussein K, Meier J, Xu L, Nerella S, Lei J, Bentley K, Hershenson M, Huang SK. PMID: 42094570; PMCID: PMC13142492.
      View in: PubMed   Mentions:
    2. Resolving fibrosis by stimulating HSC-dependent extracellular matrix degradation. Sci Transl Med. 2025 Aug 27; 17(813):eads9470. Sharma S, Prathigudupu V, Cable C, Serrano LR, Nerella S, Chen A, Hassan G, Lakins J, Valenzuela CL, Tsukui T, Ramamoorthi R, Kim JJ, Willenbring H, Mattis AN, Volk RF, Zaro BW, Coon JJ, Beresis R, DeGrado WF, Weaver VM, Christenson SA, Jo H, Chen JY. PMID: 40864684; PMCID: PMC12474517.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    3. Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. Genome Med. 2021 Apr 21; 13(1):66. Kasela S, Ortega VE, Martorella M, Garudadri S, Nguyen J, Ampleford E, Pasanen A, Nerella S, Buschur KL, Barjaktarevic IZ, Barr RG, Bleecker ER, Bowler RP, Comellas AP, Cooper CB, Couper DJ, Criner GJ, Curtis JL, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Krishnan JA, Martinez FJ, McDonald MN, Meyers DA, Paine R, Peters SP, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Levy BD, Li X, Moore WC, Wenzel SE, Zein J, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS), NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Langelier C, Woodruff PG, Lappalainen T, Christenson SA. PMID: 33883027; PMCID: PMC8059115.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    4. Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells. Cell Rep. 2021 01 05; 34(1):108573. Bunis DG, Bronevetsky Y, Krow-Lucal E, Bhakta NR, Kim CC, Nerella S, Jones N, Mendoza VF, Bryson YJ, Gern JE, Rutishauser RL, Ye CJ, Sirota M, McCune JM, Burt TD. PMID: 33406429; PMCID: PMC10263444.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    5. IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma. Am J Respir Crit Care Med. 2018 02 01; 197(3):313-324. Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG. PMID: 29064281; PMCID: PMC5811952.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    6. Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence. Alcohol Clin Exp Res. 2017 Apr; 41(4):711-718. Clark SL, McClay JL, Adkins DE, Kumar G, Aberg KA, Nerella S, Xie L, Collins AL, Crowley JJ, Quackenbush CR, Hilliard CE, Shabalin AA, Vrieze SI, Peterson RE, Copeland WE, Silberg JL, McGue M, Maes H, Iacono WG, Sullivan PF, Costello EJ, van den Oord EJ. PMID: 28196272; PMCID: PMC5378639.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction. Genome Biol. 2015 Dec 23; 16:291. McClay JL, Shabalin AA, Dozmorov MG, Adkins DE, Kumar G, Nerella S, Clark SL, Bergen SE, Swedish Schizophrenia Consortium, Hultman CM, Magnusson PK, Sullivan PF, Aberg KA, van den Oord EJ. PMID: 26699738; PMCID: PMC4699364.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    8. Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses. Nicotine Tob Res. 2016 May; 18(5):626-31. Clark SL, McClay JL, Adkins DE, Aberg KA, Kumar G, Nerella S, Xie L, Collins AL, Crowley JJ, Quakenbush CR, Hillard CE, Gao G, Shabalin AA, Peterson RE, Copeland WE, Silberg JL, Maes H, Sullivan PF, Costello EJ, van den Oord EJ. PMID: 26283763; PMCID: PMC5942610.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use. Alcohol Clin Exp Res. 2015 Aug; 39(8):1396-405. Clark SL, Aberg KA, Nerella S, Kumar G, McClay JL, Chen W, Xie LY, Harada A, Shabalin AA, Gao G, Bergen SE, Hultman CM, Magnusson PK, Sullivan PF, van den Oord EJ. PMID: 26146898; PMCID: PMC4515164.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    10. Refinement of schizophrenia GWAS loci using methylome-wide association data. Hum Genet. 2015 Jan; 134(1):77-87. Kumar G, Clark SL, McClay JL, Shabalin AA, Adkins DE, Xie L, Chan R, Nerella S, Kim Y, Sullivan PF, Hultman CM, Magnusson PK, Aberg KA, van den Oord EJ. PMID: 25284466; PMCID: PMC4282961.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    11. Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults. JAMA Psychiatry. 2014 Mar; 71(3):255-64. Aberg KA, McClay JL, Nerella S, Clark S, Kumar G, Chen W, Khachane AN, Xie L, Hudson A, Gao G, Harada A, Hultman CM, Sullivan PF, Magnusson PK, van den Oord EJ. PMID: 24402055; PMCID: PMC4331014.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansCells
    12. A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects. Hum Mol Genet. 2014 Mar 01; 23(5):1175-85. McClay JL, Aberg KA, Clark SL, Nerella S, Kumar G, Xie LY, Hudson AD, Harada A, Hultman CM, Magnusson PK, Sullivan PF, Van Den Oord EJ. PMID: 24135035; PMCID: PMC3919012.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    13. Testing two models describing how methylome-wide studies in blood are informative for psychiatric conditions. Epigenomics. 2013 Aug; 5(4):367-77. Aberg KA, Xie LY, McClay JL, Nerella S, Vunck S, Snider S, Beardsley PM, van den Oord EJ. PMID: 23895651; PMCID: PMC3904748.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    14. High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot. Epigenetics. 2013 May; 8(5):542-7. Aberg KA, Xie LY, Nerella S, Copeland WE, Costello EJ, van den Oord EJ. PMID: 23644822; PMCID: PMC3741224.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    15. MethylPCA: a toolkit to control for confounders in methylome-wide association studies. BMC Bioinformatics. 2013 Mar 02; 14:74. Chen W, Gao G, Nerella S, Hultman CM, Magnusson PK, Sullivan PF, Aberg KA, van den Oord EJ. PMID: 23452721; PMCID: PMC3599654.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    16. Estimation of CpG coverage in whole methylome next-generation sequencing studies. BMC Bioinformatics. 2013 Feb 12; 14:50. van den Oord EJ, Bukszar J, Rudolf G, Nerella S, McClay JL, Xie LY, Aberg KA. PMID: 23398781; PMCID: PMC3599116.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    17. MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case--control samples. Epigenomics. 2012 Dec; 4(6):605-21. Aberg KA, McClay JL, Nerella S, Xie LY, Clark SL, Hudson AD, Bukszár J, Adkins D, Swedish Schizophrenia Consortium, Hultman CM, Sullivan PF, Magnusson PK, van den Oord EJ. PMID: 23244307; PMCID: PMC3923085.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    18. Methylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines. Eur J Hum Genet. 2012 Sep; 20(9):953-5. Åberg K, Khachane AN, Rudolf G, Nerella S, Fugman DA, Tischfield JA, van den Oord EJ. PMID: 22378283; PMCID: PMC3421118.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
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