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Trevor Burt, MD

Title(s)Assistant Professor, Pediatrics
SchoolSchool of Medicine
Phone415-502-2525
ORCID ORCID Icon0000-0001-7933-529X Additional info
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    Collapse Biography 
    Collapse Education and Training
    Harvard UniversityM.D.2002School of Medicine
    Collapse Awards and Honors
    American Society for Clinical Investigation2014Young Physician Scientist Award
    Burroughs Wellcome Fund2014  - 2018Preterm Birth Initiative Award - Fetal Immune Activation and Lineage Switching in Preterm Birth
    University of California San Francisco2014  - 2015A Novel Approach to Study Human Fetal T Cell Differentiation and Function in vitro using iPS cells.
    UCSF-Gladstone Institute of Virology and Immunology Center for AIDS Research (CFAR) 2010  - 2011“Outside the Box” AIDS Vaccine Discovery Award
    Pediatric Scientist Development Program (PSDP)2006  - 2009PSDP Fellowship
    Sarnoff Cardiovascular Research Foundation2000  - 2001Sarnoff Fellowship

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Understanding Molecular Pathways for Fetal T Cell Development and Function
    NIH/NIAID R21AI120032Jul 1, 2015 - Jun 30, 2017
    Role: Principal Investigator
    Defining Transition from Fetal to Adult T Cell Predominance in the Human Fetus
    NIH/NICHD K08HD067295Feb 10, 2011 - Jan 31, 2016
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ng MSF, Roth TL, Mendoza VF, Marson A, Burt TD. Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. Sci Immunol. 2019 Nov 22; 4(41). PMID: 31757834.
      View in: PubMed
    2. Calderon D, Nguyen MLT, Mezger A, Kathiria A, Müller F, Nguyen V, Lescano N, Wu B, Trombetta J, Ribado JV, Knowles DA, Gao Z, Blaeschke F, Parent AV, Burt TD, Anderson MS, Criswell LA, Greenleaf WJ, Marson A, Pritchard JK. Landscape of stimulation-responsive chromatin across diverse human immune cells. Nat Genet. 2019 Sep 30. PMID: 31570894.
      View in: PubMed
    3. Halkias J, Rackaityte E, Hillman SL, Aran D, Mendoza VF, Marshall LR, MacKenzie TC, Burt TD. CD161 contributes to prenatal immune suppression of IFN?-producing PLZF+ T cells. J Clin Invest. 2019 May 30; 130:3562-3577. PMID: 31145102.
      View in: PubMed
    4. Odorizzi PM, Jagannathan P, McIntyre TI, Budker R, Prahl M, Auma A, Burt TD, Nankya F, Nalubega M, Sikyomu E, Musinguzi K, Naluwu K, Kakuru A, Dorsey G, Kamya MR, Feeney ME. In utero priming of highly functional effector T cell responses to human malaria. Sci Transl Med. 2018 10 17; 10(463). PMID: 30333241.
      View in: PubMed
    5. Kattah MG, Milush JM, Burt T, McCabe RP, Whang MI, Ma A, Mahadevan U. Correction: Anti-TNF and thiopurine therapy in pregnant IBD patients does not significantly alter a panel of B-cell and T-cell subsets in 1-year-old infants. Clin Transl Gastroenterol. 2018 07 31; 9(7):172. PMID: 30065242.
      View in: PubMed
    6. Kattah MG, Milush JM, Burt T, McCabe RP, Whang MI, Ma A, Mahadevan U. Anti-TNF and thiopurine therapy in pregnant IBD patients does not significantly alter a panel of B-cell and T-cell subsets in 1-year-old infants. Clin Transl Gastroenterol. 2018 04 03; 9(4):143. PMID: 29618720.
      View in: PubMed
    7. Bronevetsky Y, Burt TD, McCune JM. Lin28b Regulates Fetal Regulatory T Cell Differentiation through Modulation of TGF-ß Signaling. J Immunol. 2016 12 01; 197(11):4344-4350. PMID: 27793996.
      View in: PubMed
    8. Seu L, Ortiz GM, Burt TD, Deeks SG, Martin JN, McCune JM. Levels of circulating myeloid subpopulations and of heme oxygenase-1 do not predict CD4(+) T cell recovery after the initiation of antiretroviral therapy for HIV disease. AIDS Res Ther. 2014; 11:27. PMID: 25180041.
      View in: PubMed
    9. Krow-Lucal ER, Kim CC, Burt TD, McCune JM. Distinct functional programming of human fetal and adult monocytes. Blood. 2014 Mar 20; 123(12):1897-904. PMID: 24518760.
      View in: PubMed
    10. Burt TD. Fetal regulatory T cells and peripheral immune tolerance in utero: implications for development and disease. Am J Reprod Immunol. 2013 Apr; 69(4):346-58. PMID: 23432802.
      View in: PubMed
    11. Seu L, Burt TD, Witte JS, Martin JN, Deeks SG, McCune JM. Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-Americans. Genes Immun. 2012 Apr; 13(3):258-67. PMID: 22048453.
      View in: PubMed
    12. Mold JE, Venkatasubrahmanyam S, Burt TD, Michaëlsson J, Rivera JM, Galkina SA, Weinberg K, Stoddart CA, McCune JM. Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. Science. 2010 Dec 17; 330(6011):1695-9. PMID: 21164017.
      View in: PubMed
    13. Burt TD, Seu L, Mold JE, Kappas A, McCune JM. Naive human T cells are activated and proliferate in response to the heme oxygenase-1 inhibitor tin mesoporphyrin. J Immunol. 2010 Nov 01; 185(9):5279-88. PMID: 20921523.
      View in: PubMed
    14. Mold JE, Michaëlsson J, Burt TD, Muench MO, Beckerman KP, Busch MP, Lee TH, Nixon DF, McCune JM. Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. Science. 2008 Dec 05; 322(5907):1562-5. PMID: 19056990.
      View in: PubMed
    15. Burt TD, Agan BK, Marconi VC, He W, Kulkarni H, Mold JE, Cavrois M, Huang Y, Mahley RW, Dolan MJ, McCune JM, Ahuja SK. Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression. Proc Natl Acad Sci U S A. 2008 Jun 24; 105(25):8718-23. PMID: 18562290.
      View in: PubMed
    16. Napolitano LA, Burt TD, Bacchetti P, Barrón Y, French AL, Kovacs A, Anastos K, Young M, McCune JM, Greenblatt RM. Increased circulating interleukin-7 levels in HIV-1-infected women. J Acquir Immune Defic Syndr. 2005 Dec 15; 40(5):581-4. PMID: 16284535.
      View in: PubMed
    17. Hirsch GM, Kearsey J, Burt T, Karnovsky MJ, Lee T. Medial smooth muscle cell loss in arterial allografts occurs by cytolytic cell induced apoptosis. Eur J Cardiothorac Surg. 1998 Jul; 14(1):89-96; discussion 96-7. PMID: 9726621.
      View in: PubMed
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