Michael Kattah, MD, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityMD/PhD2010Medicine
    Brigham and Women's HospitalMedicine Residency2012Medicine
    UCSFGastroenterology Fellowship2016Gastroenterology/Medicine
    Collapse Awards and Honors
    Stanford University2008Hugh McDevitt Award
    Brigham and Women's Hospital2012Resident Mentoring Award
    DDW 20162016Recognition for Scientific Accomplishment as an Early Stage Investigator

    Collapse Overview 
    Collapse Overview
    As an Assistant Adjunct Professor in the Division of GI at UCSF, I am interested in the molecular underpinnings of intestinal inflammation and Inflammatory Bowel Disease (IBD). We employ various tools to study intracellular signaling proteins involved in cell death and inflammation. Currently, we are using chemical screening and proteomics to try and develop novel therapies for IBD and other autoimmune diseases.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Whang MI, Tavares RM, Benjamin DI, Kattah M, Advincula R, Nomura DK, Debnath J, Malynn BA, Ma A. The Ubiquitin Binding Protein TAX1BP1 Mediates Autophagasome Induction and the Metabolic Transition of Activated T Cells. Immunity. 2017 Mar 21; 46(3):405-420. PMID: 28314591.
      View in: PubMed
    2. Kattah MG, Mahadevan U. Confocal laser endomicroscopy for membrane-bound tumor necrosis factor predicts response to therapy in Crohn's disease. Gastroenterology. 2015 May; 148(5):1067-9. PMID: 25824357.
      View in: PubMed
    3. Kattah NH, Newell EW, Jarrell JA, Chu AD, Xie J, Kattah MG, Goldberger O, Ye J, Chakravarty EF, Davis MM, Utz PJ. Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease. Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10):3044-9. PMID: 25713364; PMCID: PMC4364210.
    4. Haddon DJ, Jarrell JA, Hughes MR, Snyder K, McNagny KM, Kattah MG, Utz PJ. Measurement of mast cell surface molecules by high-throughput immunophenotyping using transcription (HIT). Methods Mol Biol. 2015; 1220:381-400. PMID: 25388264.
      View in: PubMed
    5. Kattah MG, Mahadevan U. Insights into the molecular pathophysiology of inflammatory bowel disease: ATG16L1 suppresses nod-driven inflammation. Gastroenterology. 2014 Aug; 147(2):528-30. PMID: 24953625.
      View in: PubMed
    6. Kattah NH, Kattah MG, Utz PJ. The U1-snRNP complex: structural properties relating to autoimmune pathogenesis in rheumatic diseases. Immunol Rev. 2010 Jan; 233(1):126-45. PMID: 20192997; PMCID: PMC3074261.
    7. Lin JT, Lineberry NB, Kattah MG, Su LL, Utz PJ, Fathman CG, Wu L. Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression. J Immunol. 2009 May 15; 182(10):5919-28. PMID: 19414743; PMCID: PMC2853371.
    8. Lee JW, Wang P, Kattah MG, Youssef S, Steinman L, DeFea K, Straus DS. Differential regulation of chemokines by IL-17 in colonic epithelial cells. J Immunol. 2008 Nov 01; 181(9):6536-45. PMID: 18941244.
      View in: PubMed
    9. Chen Z, Tabakman SM, Goodwin AP, Kattah MG, Daranciang D, Wang X, Zhang G, Li X, Liu Z, Utz PJ, Jiang K, Fan S, Dai H. Protein microarrays with carbon nanotubes as multicolor Raman labels. Nat Biotechnol. 2008 Nov; 26(11):1285-92. PMID: 18953353.
      View in: PubMed
    10. Kattah MG, Coller J, Cheung RK, Oshidary N, Utz PJ. HIT: a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular proteins and surface molecules. Nat Med. 2008 Nov; 14(11):1284-9. PMID: 18849997; PMCID: PMC3334282.
    11. Kattah MG, Utz PJ, Balboni I. Protein microarrays address the elephant in the room. Clin Chem. 2008 Jun; 54(6):937-9. PMID: 18509011.
      View in: PubMed
    12. Kattah MG, Wong MT, Yocum MD, Utz PJ. Cytokines secreted in response to Toll-like receptor ligand stimulation modulate differentiation of human Th17 cells. Arthritis Rheum. 2008 Jun; 58(6):1619-29. PMID: 18512782; PMCID: PMC4124044.
    13. Pennathur S, Baldessari F, Santiago JG, Kattah MG, Steinman JB, Utz PJ. Free-solution oligonucleotide separation in nanoscale channels. Anal Chem. 2007 Nov 01; 79(21):8316-22. PMID: 17883279.
      View in: PubMed
    14. Kattah MG, Alemi GR, Thibault DL, Balboni I, Utz PJ. A new two-color Fab labeling method for autoantigen protein microarrays. Nat Methods. 2006 Sep; 3(9):745-51. PMID: 16929321.
      View in: PubMed
    15. Busch R, Byrne B, Gandrud L, Sears D, Meyer E, Kattah M, Kurihara C, Haertel E, Parnes JR, Mellins ED. Medicine on a need-to-know basis. Nat Immunol. 2006 Jun; 7(6):543-7. PMID: 16715061.
      View in: PubMed
    16. Balboni I, Chan SM, Kattah M, Tenenbaum JD, Butte AJ, Utz PJ. Multiplexed protein array platforms for analysis of autoimmune diseases. Annu Rev Immunol. 2006; 24:391-418. PMID: 16551254.
      View in: PubMed
    17. Koehler NK, Yang CY, Varady J, Lu Y, Wu XW, Liu M, Yin D, Bartels M, Xu BY, Roller PP, Long YQ, Li P, Kattah M, Cohn ML, Moran K, Tilley E, Richert JR, Wang S. Structure-based discovery of nonpeptidic small organic compounds to block the T cell response to myelin basic protein. J Med Chem. 2004 Oct 07; 47(21):4989-97. PMID: 15456243.
      View in: PubMed
    18. Radaev S, Kattah M, Rostro B, Colonna M, Sun PD. Crystal structure of the human myeloid cell activating receptor TREM-1. Structure. 2003 Dec; 11(12):1527-35. PMID: 14656437.
      View in: PubMed
    19. Radaev S, Kattah M, Zou Z, Colonna M, Sun PD. Making sense of the diverse ligand recognition by NKG2D. J Immunol. 2002 Dec 01; 169(11):6279-85. PMID: 12444134.
      View in: PubMed
    20. Sun PD, Radaev S, Kattah M. Generating isomorphous heavy-atom derivatives by a quick-soak method. Part I: test cases. Acta Crystallogr D Biol Crystallogr. 2002 Jul; 58(Pt 7):1092-8. PMID: 12077427.
      View in: PubMed
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