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    Michael Kattah, MD, PhD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    Address513 Parnassus Avenue
    San Francisco CA 94117
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      Collapse Biography 
      Collapse Education and Training
      Stanford UniversityMD/PhDMedicine2010
      Brigham and Women's HospitalMedicine ResidencyMedicine2012
      UCSFGastroenterology FellowshipGastroenterology/Medicine2016
      Collapse Awards and Honors
      Stanford University2008Hugh McDevitt Award
      Brigham and Women's Hospital2012Resident Mentoring Award
      DDW 20162016Recognition for Scientific Accomplishment as an Early Stage Investigator

      Collapse Overview 
      Collapse Overview
      As an Assistant Adjunct Professor in the Division of GI at UCSF, I am interested in the molecular underpinnings of intestinal inflammation and Inflammatory Bowel Disease (IBD). We employ various tools to study intracellular signaling proteins involved in cell death and inflammation. Currently, we are using chemical screening and proteomics to try and develop novel therapies for IBD and other autoimmune diseases.

      Collapse Interests
      Inflammatory Bowel Disease, IBD, Crohn's Disease, CD, Ulcerative Colitis, UC, Immunology, Autoimmunity, Genomics, Proteomics, Drug Development, High-throughput Screening, Intestinal Organoids, Innate Immunity, Ubiquitin, Apoptosis, Necroptosis, Precision Medicine

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Kattah MG, Mahadevan U. Confocal laser endomicroscopy for membrane-bound tumor necrosis factor predicts response to therapy in Crohn's disease. Gastroenterology. 2015 May; 148(5):1067-9. PMID: 25824357.
        View in: PubMed
      2. Kattah NH, Newell EW, Jarrell JA, Chu AD, Xie J, Kattah MG, Goldberger O, Ye J, Chakravarty EF, Davis MM, Utz PJ. Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease. Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10):3044-9. PMID: 25713364; PMCID: PMC4364210.
      3. Haddon DJ, Jarrell JA, Hughes MR, Snyder K, McNagny KM, Kattah MG, Utz PJ. Measurement of mast cell surface molecules by high-throughput immunophenotyping using transcription (HIT). Methods Mol Biol. 2015; 1220:381-400. PMID: 25388264.
        View in: PubMed
      4. Kattah MG, Mahadevan U. Insights into the molecular pathophysiology of inflammatory bowel disease: ATG16L1 suppresses nod-driven inflammation. Gastroenterology. 2014 Aug; 147(2):528-30. PMID: 24953625.
        View in: PubMed
      5. Kattah NH, Kattah MG, Utz PJ. The U1-snRNP complex: structural properties relating to autoimmune pathogenesis in rheumatic diseases. Immunol Rev. 2010 Jan; 233(1):126-45. PMID: 20192997; PMCID: PMC3074261.
      6. Lin JT, Lineberry NB, Kattah MG, Su LL, Utz PJ, Fathman CG, Wu L. Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression. J Immunol. 2009 May 15; 182(10):5919-28. PMID: 19414743; PMCID: PMC2853371.
      7. Lee JW, Wang P, Kattah MG, Youssef S, Steinman L, DeFea K, Straus DS. Differential regulation of chemokines by IL-17 in colonic epithelial cells. J Immunol. 2008 Nov 1; 181(9):6536-45. PMID: 18941244.
        View in: PubMed
      8. Chen Z, Tabakman SM, Goodwin AP, Kattah MG, Daranciang D, Wang X, Zhang G, Li X, Liu Z, Utz PJ, Jiang K, Fan S, Dai H. Protein microarrays with carbon nanotubes as multicolor Raman labels. Nat Biotechnol. 2008 Nov; 26(11):1285-92. PMID: 18953353.
        View in: PubMed
      9. Kattah MG, Coller J, Cheung RK, Oshidary N, Utz PJ. HIT: a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular proteins and surface molecules. Nat Med. 2008 Nov; 14(11):1284-9. PMID: 18849997; PMCID: PMC3334282.
      10. Kattah MG, Utz PJ, Balboni I. Protein microarrays address the elephant in the room. Clin Chem. 2008 Jun; 54(6):937-9. PMID: 18509011.
        View in: PubMed
      11. Kattah MG, Wong MT, Yocum MD, Utz PJ. Cytokines secreted in response to Toll-like receptor ligand stimulation modulate differentiation of human Th17 cells. Arthritis Rheum. 2008 Jun; 58(6):1619-29. PMID: 18512782; PMCID: PMC4124044.
      12. Pennathur S, Baldessari F, Santiago JG, Kattah MG, Steinman JB, Utz PJ. Free-solution oligonucleotide separation in nanoscale channels. Anal Chem. 2007 Nov 1; 79(21):8316-22. PMID: 17883279.
        View in: PubMed
      13. Kattah MG, Alemi GR, Thibault DL, Balboni I, Utz PJ. A new two-color Fab labeling method for autoantigen protein microarrays. Nat Methods. 2006 Sep; 3(9):745-51. PMID: 16929321.
        View in: PubMed
      14. Busch R, Byrne B, Gandrud L, Sears D, Meyer E, Kattah M, Kurihara C, Haertel E, Parnes JR, Mellins ED. Medicine on a need-to-know basis. Nat Immunol. 2006 Jun; 7(6):543-7. PMID: 16715061.
        View in: PubMed
      15. Balboni I, Chan SM, Kattah M, Tenenbaum JD, Butte AJ, Utz PJ. Multiplexed protein array platforms for analysis of autoimmune diseases. Annu Rev Immunol. 2006; 24:391-418. PMID: 16551254.
        View in: PubMed
      16. Koehler NK, Yang CY, Varady J, Lu Y, Wu XW, Liu M, Yin D, Bartels M, Xu BY, Roller PP, Long YQ, Li P, Kattah M, Cohn ML, Moran K, Tilley E, Richert JR, Wang S. Structure-based discovery of nonpeptidic small organic compounds to block the T cell response to myelin basic protein. J Med Chem. 2004 Oct 7; 47(21):4989-97. PMID: 15456243.
        View in: PubMed
      17. Radaev S, Kattah M, Rostro B, Colonna M, Sun PD. Crystal structure of the human myeloid cell activating receptor TREM-1. Structure. 2003 Dec; 11(12):1527-35. PMID: 14656437.
        View in: PubMed
      18. Radaev S, Kattah M, Zou Z, Colonna M, Sun PD. Making sense of the diverse ligand recognition by NKG2D. J Immunol. 2002 Dec 1; 169(11):6279-85. PMID: 12444134.
        View in: PubMed
      19. Sun PD, Radaev S, Kattah M. Generating isomorphous heavy-atom derivatives by a quick-soak method. Part I: test cases. Acta Crystallogr D Biol Crystallogr. 2002 Jul; 58(Pt 7):1092-8. PMID: 12077427.
        View in: PubMed
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