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Alpha-B-crystallin immunohistochemistry: A sensitive but non-specific marker for epileptogenic lesions. Brain Pathol. 2026 Feb 18; e70087.
Güney E, Caliskan I, Saunders T, Paredes M, Lucas CH, Mirchia K, Lu R, Terry M, Cagampan E, Pekmezci M, Bollen A, Perry A, Cadwell CR, Tihan T. PMID: 41709654.
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PubMed Mentions: Fields:
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Classification accuracy of a hierarchical molecular inference-based deep-learning system for CNS tumour diagnosis: a multi-institutional, retrospective study. Lancet Oncol. 2026 Feb; 27(2):243-253.
Lalchungnunga H, Dampier CH, Singh O, Hoang DT, Shulman ED, Abdullaev Z, Li B, Luo Z, Wu Z, Pearce TM, Marker DF, McCortney K, Horbinski C, Lucas CG, Cimino PJ, Nasrallah MP, Quezado M, Chung HJ, Yefet L, Zadeh G, Brandner S, Ruppin E, Aldape K. PMID: 41643698.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Radiologic characterization and clinical management of multinodular and vacuolating neuronal tumor (MVNT): a retrospective institutional cohort study. J Neurooncol. 2025 Oct 30; 176(1):57.
Carmichael A, Arshad U, Heinemann DM, Reddy SC, Kalluri A, Serrano-Farias A, Madhu P, Lakhani DA, Sair H, Schreck KC, Lucas CH, Gonzalez-Gomez I, Jallo GI, Bettegowda C, Rincon-Torroella J. PMID: 41166014.
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PubMed Mentions: Fields:
Translation:
Humans
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Serial multiomics uncovers anti-glioblastoma responses not evident by routine clinical analyses. Sci Transl Med. 2025 Oct 08; 17(819):eadv2881.
Ling AL, Gantchev J, Prabhu MC, Basu S, Ahn R, D'Souza A, Masud N, Ball A, Nikas O, Villa GR, Regan MS, Baquer G, Ayoub G, Whittaker CA, Abou-Mrad Z, Santos A, Couturier CP, Elharouni D, Vogelzang J, Yu KKH, Chen H, He Z, Jiang W, Lucas CH, Sax HE, Lang FF, Puduvalli VK, Tabar V, W Brennan C, Boire A, Holdhoff M, Bettegowda C, Cima M, Solomon IH, Yuan Y, Tak PP, Accelerating GBM Therapies TeamLab, Sharma P, White FM, Ligon KL, Agar NYR, Reardon DA, Oliveira G, Chiocca EA. PMID: 41061048.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Increased SOX10, p16, and Cyclin D1 Immunoreactivity Differentiates MAP Kinase-activated Low-grade Gliomas From Piloid Gliosis: Erratum. Am J Surg Pathol. 2025 Oct 01; 49(10):e15.
Tang V, Zhang KY, Mirchia K, Lu R, Guney E, Terry M, Ligon AH, Ligon KL, Eberhart CG, Perry A, Lucas CG. PMID: 40958153.
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PubMed Mentions: Fields:
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The role of extent of resection, chemoradiation, and MGMT promoter methylation in overall survival in a large cohort of IDH-wildtype glioblastoma. Neurosurg Focus. 2025 Aug 01; 59(2):E9.
Parker M, Carmichael A, Serrano-Farias A, Alfonzo Horowitz M, Redmond KJ, Lucas CG, Mukherjee D, Comair Y, Bettegowda C, Rincon-Torroella J. PMID: 40749242.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Impact of peri-tumoral resection on survival in primary glioblastoma. Cancer. 2025 Aug 01; 131(15):e70016.
Tang LY, Botros D, Kim AA, Khalafallah AM, Dux H, Fox K, Hussain N, Mao Y, Pellegrino R, Sharma P, Lucas CG, Ahmed AK, Jackson CM, Gallia G, Bettegowda C, Weingart J, Brem H, Mukherjee D. PMID: 40704606.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Rare Occurrence of Distant Metastases in Prolactinoma: Insights From 2 Cases and Review of the Literature. AACE Endocrinol Diabetes. 2025 Sep-Oct; 12(3):162-168.
Master V, Hann CL, Gallia GL, Lucas CG, Purohit D, Ishii M, Salvatori R. PMID: 41048690; PMCID: PMC12495570.
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PubMed Mentions:
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Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth. Nat Cell Biol. 2025 May; 27(5):863-874.
Abeysundara N, Rasnitsyn A, Fong V, Bahcheli A, Van Ommeren R, Juraschka K, Vladoiu M, Ong W, Livingston B, de Antonellis P, Ly M, Holgado BL, Sirbu O, Bahrampour S, Min HK, Fan J, Nor C, Visvanathan A, Zhang J, Wang H, Qin L, Huang N, Pallotta J, Douglas T, Mak E, Su H, Ng K, Zhang KY, Daniels C, Lucas CG, Eberhart CG, Liu H, Jiang T, Notta F, Ramaswamy V, Reimand J, Gallo M, Rich JN, Wu X, Huang X, Taylor MD. PMID: 40263572; PMCID: PMC12081294.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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PSMA PET/CT scan reveals incidental meningioma in a prostate cancer patient. Urol Case Rep. 2025 May; 60:103022.
Florou VA, Halthore A, Lucas CG, Rivera Lopez CA, Pienta KJ. PMID: 40224316; PMCID: PMC11987657.
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PubMed Mentions:
1
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Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes. Neuro Oncol. 2022 10 03; 24(10):1749-1762.
Zhang Y, Lucas CG, Young JS, Morshed RA, McCoy L, Oberheim Bush NA, Taylor JW, Daras M, Butowski NA, Villanueva-Meyer JE, Cha S, Wrensch M, Wiencke JK, Lee JC, Pekmezci M, Phillips JJ, Perry A, Bollen AW, Aghi MK, Theodosopoulos P, Chang EF, Hervey-Jumper SL, Berger MS, Clarke JL, Chang SM, Molinaro AM, Solomon DA. PMID: 35395677; PMCID: PMC9527525.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1. Acta Neuropathol. 2022 10; 144(4):747-765.
Lucas CG, Sloan EA, Gupta R, Wu J, Pratt D, Vasudevan HN, Ravindranathan A, Barreto J, Williams EA, Shai A, Whipple NS, Bruggers CS, Maher O, Nabors B, Rodriguez M, Samuel D, Brown M, Carmichael J, Lu R, Mirchia K, Sullivan DV, Pekmezci M, Tihan T, Bollen AW, Perry A, Banerjee A, Mueller S, Gupta N, Hervey-Jumper SL, Oberheim Bush NA, Daras M, Taylor JW, Butowski NA, de Groot J, Clarke JL, Raleigh DR, Costello JF, Phillips JJ, Reddy AT, Chang SM, Berger MS, Solomon DA. PMID: 35945463; PMCID: PMC9468105.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma. J Neuropathol Exp Neurol. 2022 07 19; 81(8):650-657.
Lucas CG, Davidson CJ, Alashari M, Putnam AR, Whipple NS, Bruggers CS, Mendez JS, Cheshier SH, Walker JB, Ramani B, Cadwell CR, Sullivan DV, Lu R, Mirchia K, Van Ziffle J, Devine P, Goldschmidt E, Hervey-Jumper SL, Gupta N, Oberheim Bush NA, Raleigh DR, Bollen A, Tihan T, Pekmezci M, Solomon DA, Phillips JJ, Perry A. PMID: 35703914; PMCID: PMC9297094.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Intratumor and informatic heterogeneity influence meningioma molecular classification. Acta Neuropathol. 2022 09; 144(3):579-583.
Vasudevan HN, Choudhury A, Hilz S, Villanueva-Meyer JE, Chen WC, Lucas CG, Braunstein SE, Oberheim Bush NA, Butowski N, Pekmezci M, McDermott MW, Perry A, Solomon DA, Magill ST, Raleigh DR. PMID: 35759011; PMCID: PMC9618384.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Giant cell myositis associated with metastatic thymoma and granulomatous hypercalcaemia. BMJ Case Rep. 2022 Jun 06; 15(6).
Jimenez JC, Lucas CG, LaHue SC, Sharpe BA. PMID: 35667693; PMCID: PMC9171203.
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PubMed Mentions: Fields:
Translation:
HumansCells
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A genetically distinct pediatric subtype of primary CNS large B-cell lymphoma is associated with favorable clinical outcome. Blood Adv. 2022 05 24; 6(10):3189-3193.
Güney E, Lucas CG, Qi Z, Yu J, Zhang R, Ohgami RS, Rubenstein JL, Boué DR, Schafernak K, Wertheim GB, Dahiya S, Giulino-Roth L, Attarbaschi A, Barth MJ, Kothari S, Abla O, Cohen AL, Mendez JS, Bollen A, Perry A, Tihan T, Pekmezci M, Solomon DA, Wen KW. PMID: 35157770; PMCID: PMC9131901.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Recurrent ACVR1 mutations in posterior fossa ependymoma. Acta Neuropathol. 2022 08; 144(2):373-376.
Pratt D, Lucas CG, Selvam PP, Abdullaev Z, Ketchum C, Quezado M, Armstrong TS, Gilbert MR, Papanicolau-Sengos A, Raffeld M, Choo-Wosoba H, Chan P, Whipple N, Nasrallah M, Santi M, Ramaswamy V, Giannini C, Ritzmann TA, Grundy RG, Burford A, Jones C, Hawkins C, Venneti S, Solomon DA, Aldape K. PMID: 35587280; PMCID: PMC12433320.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet. 2022 05; 54(5):649-659.
Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW, Qiu Z, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. PMID: 35534562; PMCID: PMC9374001.
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PubMed Mentions:
160 Fields:
Translation:
HumansCells
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Resection with intraoperative cesium-131 brachytherapy as salvage therapy for recurrent brain tumors. J Neurosurg. 2022 Oct 01; 137(4):924-930.
Chen WC, Lafreniere M, Phuong C, Liu SJ, Baal JD, Lometti M, Morin O, Ziemer B, Vasudevan HN, Lucas CG, Hervey-Jumper SL, Theodosopoulos PV, Magill ST, Fogh S, Nakamura JL, Boreta L, Sneed PK, McDermott MW, Raleigh DR, Braunstein SE. PMID: 35061986.
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PubMed Mentions:
11 Fields:
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Activating NTRK2 and ALK receptor tyrosine kinase fusions extend the molecular spectrum of pleomorphic xanthoastrocytomas of early childhood: a diagnostic overlap with infant-type hemispheric glioma. Acta Neuropathol. 2022 02; 143(2):283-286.
Lucas CG, Abdullaev Z, Bruggers CS, Mirchia K, Whipple NS, Alashari MM, Lowichik A, Cheshier S, Phillips JJ, Devine P, Solomon DA, Quezado M, Aldape KD, Perry A. PMID: 34910220; PMCID: PMC8742815.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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EWSR1-BEND2 fusion defines an epigenetically distinct subtype of astroblastoma. Acta Neuropathol. 2022 01; 143(1):109-113.
Lucas CG, Gupta R, Wu J, Shah K, Ravindranathan A, Barreto J, Gener M, Ginn KF, Prall OWJ, Xu H, Kee D, Ko HS, Yaqoob N, Zia N, Florez A, Cha S, Perry A, Clarke JL, Chang SM, Berger MS, Solomon DA. PMID: 34825267; PMCID: PMC8732961.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Diffuse hemispheric glioma, H3 G34-mutant: Genomic landscape of a new tumor entity and prospects for targeted therapy. Neuro Oncol. 2021 11 02; 23(11):1974-1976.
Lucas CG, Mueller S, Reddy A, Taylor JW, Oberheim Bush NA, Clarke JL, Chang SM, Gupta N, Berger MS, Perry A, Phillips JJ, Solomon DA. PMID: 34519829; PMCID: PMC8628364.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Sarcomatous Meningioma: Diagnostic Pitfalls and the Utility of Molecular Testing. J Neuropathol Exp Neurol. 2021 09 10; 80(8):764-768.
Lucas CG, Devine P, Solomon DA, Giannini C, Reifenberger G, Dahiya S, Caccamo D, Perry A. PMID: 34128073; PMCID: PMC9432138.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Targeted Next-Generation Sequencing Identifies Molecular and Genetic Events in Dedifferentiated Chondrosarcoma. Arch Pathol Lab Med. 2021 08 01; 145(8):1009-1017.
Lucas CG, Grenert JP, Horvai A. PMID: 33147331.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Low-grade glioneuronal tumors with FGFR2 fusion resolve into a single epigenetic group corresponding to 'Polymorphous low-grade neuroepithelial tumor of the young'. Acta Neuropathol. 2021 09; 142(3):595-599.
Gupta R, Lucas CG, Wu J, Barreto J, Shah K, Simon IB, Casavilca-Zambrano S, Brathwaite C, Zhou H, Caccamo D, Gilani A, Kleinschmidt-DeMasters BK, Lee JC, Perry A, Clarke JL, Chang SM, Berger MS, Solomon DA. PMID: 34322742; PMCID: PMC8357689.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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A retrospective observational study of benign anthracotic lymphadenitis and its association with PET avid lymph nodes in patients undergoing cancer evaluation. J Thorac Dis. 2021 Jul; 13(7):4228-4235.
Ivanick NM, Shrestha P, Podolsky MJ, Walavalkar V, Lucas CH, Gesthalter YB, Seeley EJ. PMID: 34422351; PMCID: PMC8339750.
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PubMed Mentions:
2
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Letter: Patterns of Intermediate- and High-Risk Meningioma Recurrence After Treatment With Postoperative External Beam Radiotherapy. Neurosurgery. 2021 06 15; 89(1):E99-E101.
Susko MS, Chen WC, Vasudevan HN, Magill ST, Lucas CG, Oberheim Bush NA, Solomon DA, Theodosopoulos PV, McDermott MW, Villanueva-Meyer JE, Boreta L, Nakamura JL, Sneed PK, Braunstein SE, Raleigh DR. PMID: 33887769; PMCID: PMC8203419.
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PubMed Mentions:
1 Fields:
-
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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A Prognostic Gene-Expression Signature and Risk Score for Meningioma Recurrence After Resection. Neurosurgery. 2020 12 15; 88(1):202-210.
Chen WC, Vasudevan HN, Choudhury A, Pekmezci M, Lucas CG, Phillips J, Magill ST, Susko MS, Braunstein SE, Oberheim Bush NA, Boreta L, Nakamura JL, Villanueva-Meyer JE, Sneed PK, Perry A, McDermott MW, Solomon DA, Theodosopoulos PV, Raleigh DR. PMID: 32860417; PMCID: PMC7735867.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Primary Central Nervous System Lymphomas: A Diagnostic Overview of Key Histomorphologic, Immunophenotypic, and Genetic Features. Diagnostics (Basel). 2020 Dec 11; 10(12).
Lauw MIS, Lucas CG, Ohgami RS, Wen KW. PMID: 33322508; PMCID: PMC7764608.
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PubMed Mentions:
25
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Histopathologic findings in malignant peripheral nerve sheath tumor predict response to radiotherapy and overall survival. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa131.
Lucas CG, Vasudevan HN, Chen WC, Magill ST, Braunstein SE, Jacques L, Dahiya S, Rodriguez FJ, Horvai AE, Perry A, Pekmezci M, Raleigh DR. PMID: 33880447; PMCID: PMC8044670.
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PubMed Mentions:
15
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Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor. Acta Neuropathol Commun. 2020 08 28; 8(1):151.
Lucas CG, Gupta R, Doo P, Lee JC, Cadwell CR, Ramani B, Hofmann JW, Sloan EA, Kleinschmidt-DeMasters BK, Lee HS, Wood MD, Grafe M, Born D, Vogel H, Salamat S, Puccetti D, Scharnhorst D, Samuel D, Cooney T, Cham E, Jin LW, Khatib Z, Maher O, Chamyan G, Brathwaite C, Bannykh S, Mueller S, Kline CN, Banerjee A, Reddy A, Taylor JW, Clarke JL, Oberheim Bush NA, Butowski N, Gupta N, Auguste KI, Sun PP, Roland JL, Raffel C, Aghi MK, Theodosopoulos P, Chang E, Hervey-Jumper S, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Chang S, Berger MS, Perry A, Solomon DA. PMID: 32859279; PMCID: PMC7456392.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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Clinicopathological features and outcomes of parenchymal rejection in liver transplant biopsies. Histopathology. 2020 May; 76(6):822-831.
Fels Elliott DR, Tavakol M, Lucas CH, Sheahon K, Kakar S, Hameed B, Ferrell LD, Gill RM. PMID: 31894595.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Coccidioidomycosis Presenting with Fever and Back Pain. J Gen Intern Med. 2020 06; 35(6):1887-1888.
Pillsbury MM, Rubio LA, Lucas CG, Babik JM. PMID: 32185657; PMCID: PMC7280379.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Educational Case: Mitochondrial Myopathy. Acad Pathol. 2019 Jan-Dec; 6:2374289519888732.
Lucas CG, Margeta M. PMID: 31828221; PMCID: PMC6886267.
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PubMed Mentions:
2
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Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features. Brain Pathol. 2020 05; 30(3):479-494.
Lucas CG, Villanueva-Meyer JE, Whipple N, Oberheim Bush NA, Cooney T, Chang S, McDermott M, Berger M, Cham E, Sun PP, Putnam A, Zhou H, Bollo R, Cheshier S, Poppe MM, Fung KM, Sung S, Glenn C, Fan X, Bannykh S, Hu J, Danielpour M, Li R, Alva E, Johnston J, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. PMID: 31609499; PMCID: PMC7780370.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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A review of recently described genetic alterations in central nervous system tumors. Hum Pathol. 2020 02; 96:56-66.
Lucas CG, Solomon DA, Perry A. PMID: 31678207.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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ALK-positive histiocytosis with KIF5B-ALK fusion in the central nervous system. Acta Neuropathol. 2019 08; 138(2):335-337.
Lucas CG, Gilani A, Solomon DA, Liang X, Maher OM, Chamyan G, Kleinschmidt-Demasters BK, Perry A. PMID: 31119374; PMCID: PMC6712982.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Meningioma metastases: incidence and proposed screening paradigm. J Neurosurg. 2020 05 01; 132(5):1447-1455.
Dalle Ore CL, Magill ST, Yen AJ, Shahin MN, Lee DS, Lucas CG, Chen WC, Viner JA, Aghi MK, Theodosopoulos PV, Raleigh DR, Villanueva-Meyer JE, McDermott MW. PMID: 30952122.
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PubMed Mentions:
45 Fields:
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Preoperative MR Imaging to Differentiate Chordoid Meningiomas from Other Meningioma Histologic Subtypes. AJNR Am J Neuroradiol. 2019 03; 40(3):433-439.
Baal JD, Chen WC, Solomon DA, Pai JS, Lucas CH, Hara JH, Oberheim Bush NA, McDermott MW, Raleigh DR, Villanueva-Meyer JE. PMID: 30819773; PMCID: PMC6420369.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Surgical Outcomes, Complications, and Management Strategies for Foramen Magnum Meningiomas. J Neurol Surg B Skull Base. 2019 Feb; 80(1):1-9.
Magill ST, Shahin MN, Lucas CG, Yen AJ, Lee DS, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. PMID: 30733894; PMCID: PMC6365236.
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PubMed Mentions:
5
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View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
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Tuberculum sellae meningiomas: grading scale to assess surgical outcomes using the transcranial versus transsphenoidal approach. Neurosurg Focus. 2018 04; 44(4):E9.
Magill ST, Morshed RA, Lucas CG, Aghi MK, Theodosopoulos PV, Berger MS, de Divitiis O, Solari D, Cappabianca P, Cavallo LM, McDermott MW. PMID: 29606045.
View in:
PubMed Mentions:
44 Fields:
Translation:
Humans
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Cortical neurons are a prominent source of the proinflammatory cytokine osteopontin in HIV-associated neurocognitive disorders. J Neurovirol. 2015 Apr; 21(2):174-85.
Silva K, Hope-Lucas C, White T, Hairston TK, Rameau T, Brown A. PMID: 25636782; PMCID: PMC4372685.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Altered subcellular localization of the NeuN/Rbfox3 RNA splicing factor in HIV-associated neurocognitive disorders (HAND). Neurosci Lett. 2014 Jan 13; 558:97-102.
Lucas CH, Calvez M, Babu R, Brown A. PMID: 24215932; PMCID: PMC3880598.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells