Irina Proekt, PhD

Title(s)Assistant Researcher, Diabetes Center
SchoolSchool of Medicine
Phone415-502-9581
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Validation of a murine proteome-wide phage display library for identification of autoantibody specificities. JCI Insight. 2023 Dec 08; 8(23). Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik CR, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, DeRisi JL. PMID: 37934865.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance. Sci Immunol. 2023 10 27; 8(88):eabq3109. Sin JH, Sucharov J, Kashyap S, Wang Y, Proekt I, Liu X, Parent AV, Gupta A, Kastner P, Chan S, Gardner JM, Ntranos V, Miller CN, Anderson MS, Schjerven H, Waterfield MR. PMID: 37889983.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. Validation of a murine proteome-wide phage display library for the identification of autoantibody specificities. bioRxiv. 2023 Apr 07. Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik C, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, DeRisi JL. PMID: 37066405; PMCID: PMC10104109.
      View in: PubMed   Mentions:
    4. Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq. Elife. 2022 10 27; 11. Vazquez SE, Mann SA, Bodansky A, Kung AF, Quandt Z, Ferré EMN, Landegren N, Eriksson D, Bastard P, Zhang SY, Liu J, Mitchell A, Proekt I, Yu D, Mandel-Brehm C, Wang CY, Miao B, Sowa G, Zorn K, Chan AY, Tagi VM, Shimizu C, Tremoulet A, Lynch K, Wilson MR, Kämpe O, Dobbs K, Delmonte OM, Bacchetta R, Notarangelo LD, Burns JC, Casanova JL, Lionakis MS, Torgerson TR, Anderson MS, DeRisi JL. PMID: 36300623; PMCID: PMC9711525.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    5. Thymic regulatory T cells arise via two distinct developmental programs. Nat Immunol. 2019 02; 20(2):195-205. Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, Farrar MA. PMID: 30643267; PMCID: PMC6650268.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    6. Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature. 2018 07; 559(7715):627-631. Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS. PMID: 30022164; PMCID: PMC6062473.
      View in: PubMed   Mentions: 142     Fields:    Translation:HumansAnimalsCells
    7. Insights into immune tolerance from AIRE deficiency. Curr Opin Immunol. 2017 Dec; 49:71-78. Proekt I, Miller CN, Lionakis MS, Anderson MS. PMID: 29065385; PMCID: PMC5705335.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    8. LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity. J Clin Invest. 2016 10 03; 126(10):3758-3771. Proekt I, Miller CN, Jeanne M, Fasano KJ, Moon JJ, Lowell CA, Gould DB, Anderson MS, DeFranco AL. PMID: 27571405; PMCID: PMC5087700.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    9. Identification of a novel cis-regulatory element essential for immune tolerance. J Exp Med. 2015 Nov 16; 212(12):1993-2002. LaFlam TN, Seumois G, Miller CN, Lwin W, Fasano KJ, Waterfield M, Proekt I, Vijayanand P, Anderson MS. PMID: 26527800; PMCID: PMC4647269.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    10. Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4448-57. Yoshida H, Bansal K, Schaefer U, Chapman T, Rioja I, Proekt I, Anderson MS, Prinjha RK, Tarakhovsky A, Benoist C, Mathis D. PMID: 26216992; PMCID: PMC4538633.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    11. Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells. Eur J Immunol. 2011 Dec; 41(12):3645-55. Gross AJ, Proekt I, DeFranco AL. PMID: 21928281; PMCID: PMC3517141.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    12. Natural killer cells in NOD.NK1.1 mice acquire cytolytic function during viral infection and provide protection against cytomegalovirus. Proc Natl Acad Sci U S A. 2010 Sep 07; 107(36):15844-9. Orr MT, Beilke JN, Proekt I, Lanier LL. PMID: 20733071; PMCID: PMC2936652.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    13. Notch/Delta signaling constrains reengineering of pro-T cells by PU.1. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):11993-8. Franco CB, Scripture-Adams DD, Proekt I, Taghon T, Weiss AH, Yui MA, Adams SL, Diamond RA, Rothenberg EV. PMID: 16880393; PMCID: PMC1567686.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    14. Somatostatin receptor type 5 modulates somatostatin receptor type 2 regulation of adrenocorticotropin secretion. J Biol Chem. 2005 Jun 24; 280(25):24011-21. Ben-Shlomo A, Wawrowsky KA, Proekt I, Wolkenfeld NM, Ren SG, Taylor J, Culler MD, Melmed S. PMID: 15857828.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
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