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John Kane, MD, PhD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentMedicine
Address555 Mission Bay Blvd South
San Francisco CA 94158
Phone415-476-1517
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPh.D.1971 Graduate Division (Biochemistry)

    Collapse Research 
    Collapse Research Activities and Funding
    Developing Strategies to Reduce DUP in the Age of Social Medial and the Internet
    NIH R34MH103835Aug 1, 2014 - Jun 30, 2016
    Role: Principal Investigator
    Early Phase Psychosis: Informing Treatment Decisions
    NIH P30MH090590Jul 27, 2010 - Apr 30, 2015
    Role: Principal Investigator
    Dissecting Heterogeneity of Treatment Response of First Episode Schizophrenia
    NIH P50MH080173May 9, 2008 - Apr 30, 2014
    Role: Principal Investigator
    Relapse Prevention Study: Steering and Implementation
    NIH U01MH070023Feb 1, 2006 - Dec 31, 2011
    Role: Principal Investigator
    Early Phase Schizophrenia: Optimizing Outcomes
    NIH P30MH074543Sep 28, 2005 - Jun 30, 2010
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR018535Jul 1, 2003 - Mar 31, 2012
    Role: Co-Investigator
    Treating Refractory Childhood Schizophrenia
    NIH R01MH060229Sep 1, 2001 - Jul 31, 2007
    Role: Principal Investigator
    COURSE OF ILLNESS IN SCHIZOPHRENIA: OPTIMIZING OUTCOMES
    NIH P30MH060575Feb 18, 2000 - Jan 31, 2006
    Role: Principal Investigator
    Preventing Morbidity in First Episode Schizophrenia
    NIH R01MH060004Sep 30, 1998 - Jun 30, 2010
    Role: Principal Investigator
    SPECIATION OF HDL AND LDL
    NIH/NHLBI R01HL050782Apr 1, 1994 - Mar 31, 1999
    Role: Principal Investigator
    NEW ANTIPSYCHOTICS--CLINICAL TRIALS AND FOLLOWUP
    NIH R01MH046633Apr 1, 1992 - Mar 31, 1999
    Role: Principal Investigator
    SCIENTIFIC AND TECHNICAL EVALUATION AWARD
    NIH U09MH049952Jan 15, 1992 - Oct 31, 1993
    Role: Principal Investigator
    TREATMENT OF NEUROLEPTIC NONRESPONSIVE SCHIZOPHRENIA
    NIH R01MH042929Aug 1, 1987 - Jul 31, 1992
    Role: Principal Investigator
    STUDY OF SCHIZOPHRENIA
    NIH P30MH041960Sep 25, 1986 - Dec 31, 1999
    Role: Principal Investigator
    CLINICAL RESEARCH CENTER FOR THE STUDY OF SCHIZOPHRENIA
    NIH P50MH041960Sep 25, 1986 - Dec 31, 1996
    Role: Principal Investigator
    PROSPECTIVE STUDY OF TARDIVE DYSKINESIA IN THE ELDERLY
    NIH R01MH040015Mar 1, 1986 - Nov 30, 1995
    Role: Principal Investigator
    TREATMENT STRATEGIES IN SCHIZOPHRENIA
    NIH U10MH039992Sep 20, 1984 - Aug 31, 1993
    Role: Principal Investigator
    High-Density Lipoprotein Species--Structures and Roles
    NIH/NHLBI R01HL031210Jul 1, 1984 - Aug 31, 2007
    Role: Principal Investigator
    LITHIUM LEVELS AND NEUROLEPTICS IN BIPOLAR ILLNESS
    NIH R01MH037576Sep 24, 1982 - Aug 31, 1988
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    PROSPECTIVE STUDY OF TARDIVE DYSKINESIA DEVELOPMENT
    NIH R01MH032369Mar 1, 1979 - Mar 31, 2004
    Role: Principal Investigator
    PROSPECTIVE STUDY OF TARDIVE DYSKINESIA DEVELOPMENT
    NIH R37MH032369Mar 1, 1979 - Mar 31, 1998
    Role: Principal Investigator
    SCOR IN ARTERIOSCLEROSIS
    NIH P50HL014237Dec 1, 1976 - Nov 30, 1997
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Clinical Trials
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hayne CK, Lafferty MJ, Eglinger BJ, Kane J, Neher SB. Biochemical Analysis of the LPL Truncation Variant, LPLS447X Reveals Increased Lipoprotein Uptake. Biochemistry. 2016 Dec 16. PMID: 27984852.
      View in: PubMed
    2. Kane J, Malloy MJ. Lipoproteins and amyloid vascular disease. Curr Opin Lipidol. 2016 Dec; 27(6):640-641. PMID: 27805977.
      View in: PubMed
    3. Versmissen J, Vongpromek R, Yahya R, van der Net JB, van Vark-van der Zee L, Blommesteijn-Touw J, Wattimena D, Rietveld T, Pullinger CR, Christoffersen C, Dahlbäck B, Kane J, Mulder M, Sijbrands EJ. Familial hypercholesterolaemia: cholesterol efflux and coronary disease. Eur J Clin Invest. 2016 Jul; 46(7):643-50. PMID: 27208892.
      View in: PubMed
    4. Kane J. Infectious basophilia? Am J Hematol. 2016 Feb; 91(2):E8. PMID: 26572775.
      View in: PubMed
    5. Kane J, Malloy MJ. Emerging molecular strategies for management of dyslipidemias. Curr Opin Lipidol. 2015 Dec; 26(6):601-2. PMID: 26780015.
      View in: PubMed
    6. Nicholls SJ, Ruotolo G, Brewer HB, Kane J, Wang MD, Krueger KA, Adelman SJ, Nissen SE, Rader DJ. Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib. J Am Coll Cardiol. 2015 Nov 17; 66(20):2201-10. PMID: 26564598.
      View in: PubMed
    7. Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane J, Hart DO, Kwok PY, Deo RC. An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish. Elife. 2015; 4. PMID: 26473617.
      View in: PubMed
    8. Pullinger CR, Stock EO, Movsesyan I, Malloy MJ, Frost PH, Tripuraneni R, Quinn AG, Ishida BY, Schaefer EJ, Asztalos BF, Kane J. Identification and metabolic profiling of patients with lysosomal acid lipase deficiency. J Clin Lipidol. 2015 Sep-Oct; 9(5):716-26.e1. PMID: 26350820.
      View in: PubMed
    9. Kane J, Malloy MJ, Pullinger CR. HDL cholesterol efflux capacity and cardiovascular events. N Engl J Med. 2015 May 7; 372(19):1871. PMID: 25946301.
      View in: PubMed
    10. Stitziel NO, Peloso GM, Abifadel M, Cefalu AB, Fouchier S, Motazacker MM, Tada H, Larach DB, Awan Z, Haller JF, Pullinger CR, Varret M, Rabès JP, Noto D, Tarugi P, Kawashiri MA, Nohara A, Yamagishi M, Risman M, Deo R, Ruel I, Shendure J, Nickerson DA, Wilson JG, Rich SS, Gupta N, Farlow DN, Neale BM, Daly MJ, Kane J, Freeman MW, Genest J, Rader DJ, Mabuchi H, Kastelein JJ, Hovingh GK, Averna MR, Gabriel S, Boileau C, Kathiresan S. Exome sequencing in suspected monogenic dyslipidemias. Circ Cardiovasc Genet. 2015 Apr; 8(2):343-50. PMID: 25632026; PMCID: PMC4406825.
      View in: PubMed, PubMed Central
    11. Malloy MJ, Kane J. Congenital absence of apolipoprotein E and neurological function-reply. JAMA Neurol. 2014 Dec; 71(12):1579. PMID: 25486213.
      View in: PubMed
    12. Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, Castellano JM, Wyss-Coray T, Duncan JL, Miller BL, Kane J, Kwok PY, Malloy MJ. Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. JAMA Neurol. 2014 Oct; 71(10):1228-36. PMID: 25111166.
      View in: PubMed
    13. Sharma V, Witkowski A, Witkowska HE, Dykstra A, Simonsen JB, Nelbach L, Beckstead JA, Pullinger CR, Kane J, Malloy MJ, Watson G, Forte TM, Ryan RO. Aberrant hetero-disulfide bond formation by the hypertriglyceridemia-associated p.Gly185Cys APOA5 variant (rs2075291). Arterioscler Thromb Vasc Biol. 2014 Oct; 34(10):2254-60. PMID: 25127531; PMCID: PMC4178935.
      View in: PubMed, PubMed Central
    14. Valayannopoulos V, Malinova V, Honzík T, Balwani M, Breen C, Deegan PB, Enns GM, Jones SA, Kane J, Stock EO, Tripuraneni R, Eckert S, Schneider E, Hamilton G, Middleton MS, Sirlin C, Kessler B, Bourdon C, Boyadjiev SA, Sharma R, Twelves C, Whitley CB, Quinn AG. Sebelipase alfa over 52 weeks reduces serum transaminases, liver volume and improves serum lipids in patients with lysosomal acid lipase deficiency. J Hepatol. 2014 Nov; 61(5):1135-42. PMID: 24993530; PMCID: PMC4203712.
      View in: PubMed, PubMed Central
    15. Arndt C, Leclercq I, Nazeyrollas P, Durlach A, Ducasse A, Movesayan I, Socquard E, Clavel C, Malloy MM, Pullinger CR, Kane J, Durlach V. Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients. Diabetes Metab. 2014 Dec; 40(6):452-8. PMID: 24852509.
      View in: PubMed
    16. Rowland CM, Pullinger CR, Luke MM, Shiffman D, Green L, Movsesyan I, Devlin JJ, Malloy MJ, Kane J, Undas A. Lipoprotein (a), LPA Ile4399Met, and fibrin clot properties. Thromb Res. 2014 May; 133(5):863-7. PMID: 24502962.
      View in: PubMed
    17. Pullinger CR, Goldfine ID, Tanyolaç S, Movsesyan I, Faynboym M, Durlach V, Chiefari E, Foti DP, Frost PH, Malloy MJ, Brunetti A, Kane J. Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population. Metab Syndr Relat Disord. 2014 Feb; 12(1):25-30. PMID: 24148075.
      View in: PubMed
    18. Kane J, Malloy MJ. Needed: a better understanding of the antiatherogenic properties of HDL. Curr Opin Lipidol. 2013 Oct; 24(5):453-4. PMID: 24005220.
      View in: PubMed
    19. Kane J. New horizons in lipid management. J Am Coll Cardiol. 2013 Sep 24; 62(13):1163-4. PMID: 23770169.
      View in: PubMed
    20. Hossain GS, Lynn EG, Maclean KN, Zhou J, Dickhout JG, Lhoták S, Trigatti B, Capone J, Rho J, Tang D, McCulloch CA, Al-Bondokji I, Malloy MJ, Pullinger CR, Kane J, Li Y, Shiffman D, Austin RC. Deficiency of TDAG51 protects against atherosclerosis by modulating apoptosis, cholesterol efflux, and peroxiredoxin-1 expression. J Am Heart Assoc. 2013 Jun; 2(3):e000134. PMID: 23686369; PMCID: PMC3698773.
      View in: PubMed, PubMed Central
    21. Balwani M, Breen C, Enns GM, Deegan PB, Honzík T, Jones S, Kane J, Malinova V, Sharma R, Stock EO, Valayannopoulos V, Wraith JE, Burg J, Eckert S, Schneider E, Quinn AG. Clinical effect and safety profile of recombinant human lysosomal acid lipase in patients with cholesteryl ester storage disease. Hepatology. 2013 Sep; 58(3):950-7. PMID: 23348766; PMCID: PMC3728169.
      View in: PubMed, PubMed Central
    22. Malloy MJ, Kane J. Hyperlipidemia and cardiovascular disease. Curr Opin Lipidol. 2012 Dec; 23(6):591-2. PMID: 23160407.
      View in: PubMed
    23. Kane J, Malloy MJ. Prebeta-1 HDL and coronary heart disease. Curr Opin Lipidol. 2012 Aug; 23(4):367-71. PMID: 22517613.
      View in: PubMed
    24. Charles MA, Kane J. New molecular insights into CETP structure and function: a review. J Lipid Res. 2012 Aug; 53(8):1451-8. PMID: 22679067; PMCID: PMC3540851.
      View in: PubMed, PubMed Central
    25. Jordan CT, Cao L, Roberson ED, Duan S, Helms CA, Nair RP, Duffin KC, Stuart PE, Goldgar D, Hayashi G, Olfson EH, Feng BJ, Pullinger CR, Kane J, Wise CA, Goldbach-Mansky R, Lowes MA, Peddle L, Chandran V, Liao W, Rahman P, Krueger GG, Gladman D, Elder JT, Menter A, Bowcock AM. Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis. Am J Hum Genet. 2012 May 4; 90(5):796-808. PMID: 22521419; PMCID: PMC3376540.
      View in: PubMed, PubMed Central
    26. Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane J, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2012 Jun; 9(6):961-7. PMID: 22300662; PMCID: PMC3349006.
      View in: PubMed, PubMed Central
    27. Luke MM, Berger K, Rowland CM, Catanese JJ, Tong CH, Ross DA, Garcia V, Kuhlenbaeumer G, Ringelstein EB, Pullinger CR, Malloy MJ, Deedwania P, Ellis SG, Kane J, Devlin JJ, Lalouschek W, Mannhalter C. Polymorphisms and noncardioembolic stroke in three case-control studies. Cerebrovasc Dis. 2012; 33(1):80-5. PMID: 22134093.
      View in: PubMed
    28. Waugh JL, Celver J, Sharma M, Dufresne RL, Terzi D, Risch SC, Fairbrother WG, Neve RL, Kane J, Malloy MJ, Pullinger CR, Gu HF, Tsatsanis C, Hamilton SP, Gold SJ, Zachariou V, Kovoor A. Association between regulator of G protein signaling 9-2 and body weight. PLoS One. 2011; 6(11):e27984. PMID: 22132185; PMCID: PMC3223194.
      View in: PubMed, PubMed Central
    29. Guey LT, Pullinger CR, Ishida BY, O'Connor PM, Zellner C, Francone OL, Laramie JM, Naya-Vigne JM, Siradze KA, Deedwania P, Redberg RF, Frost PH, Seymour AB, Kane J, Malloy MJ. Relation of increased prebeta-1 high-density lipoprotein levels to risk of coronary heart disease. Am J Cardiol. 2011 Aug 1; 108(3):360-6. PMID: 21757044.
      View in: PubMed
    30. DuBois SG, Goldsby R, Segal M, Woo J, Copren K, Kane J, Pullinger CR, Matthay KK, Witte J, Lessnick SL, Robison LL, Bhatia S, Strong LC. Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2012 Jul 15; 59(1):52-6. PMID: 21793187; PMCID: PMC3204324.
      View in: PubMed, PubMed Central
    31. Ruaño G, Windemuth A, Wu AH, Kane J, Malloy MJ, Pullinger CR, Kocherla M, Bogaard K, Gordon BR, Holford TR, Gupta A, Seip RL, Thompson PD. Mechanisms of statin-induced myalgia assessed by physiogenomic associations. Atherosclerosis. 2011 Oct; 218(2):451-6. PMID: 21868014; PMCID: PMC3224998.
      View in: PubMed, PubMed Central
    32. Francone OL, Ishida BY, de la Llera-Moya M, Royer L, Happe C, Zhu J, Chalkey RJ, Schaefer P, Cox C, Burlingame A, Kane J, Rothblat GH. Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels. J Lipid Res. 2011 Nov; 52(11):1974-83. PMID: 21771977; PMCID: PMC3196229.
      View in: PubMed, PubMed Central
    33. Chiefari E, Tanyolaç S, Paonessa F, Pullinger CR, Capula C, Iiritano S, Mazza T, Forlin M, Fusco A, Durlach V, Durlach A, Malloy MJ, Kane J, Heiner SW, Filocamo M, Foti DP, Goldfine ID, Brunetti A. Functional variants of the HMGA1 gene and type 2 diabetes mellitus. JAMA. 2011 Mar 2; 305(9):903-12. PMID: 21364139.
      View in: PubMed
    34. Durlach V, Durlach A, Movesayan I, Socquard E, Zellner C, Clavel C, Nazeyrollas P, Malloy MJ, Pullinger CR, Kane J, Ducasse A, Aouizerat BE. Association of endothelial lipase Thr111Ile polymorphism with lipid metabolism and microvascular complications in type 2 diabetic patients. Diabetes Metab. 2011 Feb; 37(1):64-71. PMID: 21145773.
      View in: PubMed
    35. Zhang L, Song J, Cavigiolio G, Ishida BY, Zhang S, Kane J, Weisgraber KH, Oda MN, Rye KA, Pownall HJ, Ren G. Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy. J Lipid Res. 2011 Jan; 52(1):175-84. PMID: 20978167; PMCID: PMC2999936.
      View in: PubMed, PubMed Central
    36. Ruaño G, Thompson PD, Kane J, Pullinger CR, Windemuth A, Seip RL, Kocherla M, Holford TR, Wu AH. Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Pharmacogenomics. 2010 Jul; 11(7):959-71. PMID: 20602615; PMCID: PMC2921920.
      View in: PubMed, PubMed Central
    37. Pullinger CR, Aouizerat BE, Gay C, Coggins T, Movsesyan I, Davis H, Kane J, Portillo C, Lee KA. Metabolic abnormalities and coronary heart disease risk in human immunodeficiency virus-infected adults. Metab Syndr Relat Disord. 2010 Jun; 8(3):279-86. PMID: 20235745; PMCID: PMC3085320.
      View in: PubMed, PubMed Central
    38. Shiffman D, Louie JZ, Rowland CM, Malloy MJ, Kane J, Devlin JJ. Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus. Atherosclerosis. 2010 Sep; 212(1):193-6. PMID: 20605575.
      View in: PubMed
    39. Pan J, Shilian P, Ishida B, Wu X, Kane J, Malloy MJ, Charles MA. Effect of niacin on preß-1 high-density lipoprotein levels in diabetes. Metabolism. 2011 Feb; 60(2):292-7. PMID: 20303127.
      View in: PubMed
    40. Fujimoto VY, Kane J, Ishida BY, Bloom MS, Browne RW. High-density lipoprotein metabolism and the human embryo. Hum Reprod Update. 2010 Jan-Feb; 16(1):20-38. PMID: 19700490.
      View in: PubMed
    41. Tanyolaç S, Bremer AA, Hodoglugil U, Movsesyan I, Pullinger CR, Heiner SW, Malloy MJ, Kane J, Goldfine ID. Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects. Metab Syndr Relat Disord. 2009 Dec; 7(6):543-8. PMID: 19656007; PMCID: PMC3139525.
      View in: PubMed, PubMed Central
    42. Arai K, Luke MM, Koschinsky ML, Miller ER, Pullinger CR, Witztum JL, Kane J, Tsimikas S. The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles. Atherosclerosis. 2010 Apr; 209(2):498-503. PMID: 19880117.
      View in: PubMed
    43. Ortiz-Muñoz G, Houard X, Martín-Ventura JL, Ishida BY, Loyau S, Rossignol P, Moreno JA, Kane J, Chalkley RJ, Burlingame AL, Michel JB, Meilhac O. HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property. FASEB J. 2009 Sep; 23(9):3129-39. PMID: 19417089; PMCID: PMC2735359.
      View in: PubMed, PubMed Central
    44. Duncan KG, Hosseini K, Bailey KR, Yang H, Lowe RJ, Matthes MT, Kane J, LaVail MM, Schwartz DM, Duncan JL. Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium. Br J Ophthalmol. 2009 Aug; 93(8):1116-20. PMID: 19304587; PMCID: PMC3541028.
      View in: PubMed, PubMed Central
    45. Zhu J, Gardner J, Pullinger CR, Kane J, Thompson JF, Francone OL. Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1. J Lipid Res. 2009 Jul; 50(7):1330-9. PMID: 19237735; PMCID: PMC2694332.
      View in: PubMed, PubMed Central
    46. Calton MA, Ersoy BA, Zhang S, Kane J, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R, Ahituv N, Vaisse C. Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Hum Mol Genet. 2009 Mar 15; 18(6):1140-7. PMID: 19091795; PMCID: PMC2649015.
      View in: PubMed, PubMed Central
    47. Meyer TE, Shiffman D, Morrison AC, Rowland CM, Louie JZ, Bare LA, Ross DA, Arellano AR, Chasman DI, Ridker PM, Pankow JS, Coresh J, Malloy MJ, Kane J, Ellis SG, Devlin JJ, Boerwinkle E. GOSR2 Lys67Arg is associated with hypertension in whites. Am J Hypertens. 2009 Feb; 22(2):163-8. PMID: 19057520; PMCID: PMC4346180.
      View in: PubMed, PubMed Central
    48. Plaisier CL, Kyttälä M, Weissglas-Volkov D, Sinsheimer JS, Huertas-Vazquez A, Riba L, Ramírez-Jiménez S, de Bruin TW, Tusié-Luna T, Aouizerat BE, Pullinger CR, Malloy MJ, Kane J, Cruz-Bautista I, Herrera MF, Aguilar-Salinas C, Kuusisto J, Laakso M, Taskinen MR, van der Kallen CJ, Pajukanta P. Galanin preproprotein is associated with elevated plasma triglycerides. Arterioscler Thromb Vasc Biol. 2009 Jan; 29(1):147-52. PMID: 18988886; PMCID: PMC2650822.
      View in: PubMed, PubMed Central
    49. Shiffman D, Kane J, Louie JZ, Arellano AR, Ross DA, Catanese JJ, Malloy MJ, Ellis SG, Devlin JJ. Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction. PLoS One. 2008; 3(8):e2895. PMID: 18682748; PMCID: PMC2483345.
      View in: PubMed, PubMed Central
    50. van der Net JB, Versmissen J, Oosterveer DM, Defesche JC, Yazdanpanah M, Aouizerat BE, Steyerberg EW, Malloy MJ, Pullinger CR, Kane J, Kastelein JJ, Sijbrands EJ. Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and coronary heart disease risk in familial hypercholesterolemia. Atherosclerosis. 2009 Apr; 203(2):472-8. PMID: 18775537.
      View in: PubMed
    51. Lee JC, Weissglas-Volkov D, Kyttälä M, Dastani Z, Cantor RM, Sobel EM, Plaisier CL, Engert JC, van Greevenbroek MM, Kane J, Malloy MJ, Pullinger CR, Huertas-Vazquez A, Aguilar-Salinas CA, Tusie-Luna T, de Bruin TW, Aouizerat BE, van der Kallen CC, Croce CM, Aqeilan RI, Marcil M, Viikari JS, Lehtimäki T, Raitakari OT, Kuusisto J, Laakso M, Taskinen MR, Genest J, Pajukanta P. WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels. Am J Hum Genet. 2008 Aug; 83(2):180-92. PMID: 18674750; PMCID: PMC2495060.
      View in: PubMed, PubMed Central
    52. van der Net JB, Oosterveer DM, Versmissen J, Defesche JC, Yazdanpanah M, Aouizerat BE, Steyerberg EW, Malloy MJ, Pullinger CR, Kastelein JJ, Kane J, Sijbrands EJ. Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. Eur Heart J. 2008 Sep; 29(18):2195-201. PMID: 18599554; PMCID: PMC2733738.
      View in: PubMed, PubMed Central
    53. Pullinger CR, Aouizerat BE, Movsesyan I, Durlach V, Sijbrands EJ, Nakajima K, Poon A, Dallinga-Thie GM, Hattori H, Green LL, Kwok PY, Havel RJ, Frost PH, Malloy MJ, Kane J. An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients. J Lipid Res. 2008 Aug; 49(8):1846-54. PMID: 18441017; PMCID: PMC2444008.
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    54. Liu Y, Helms C, Liao W, Zaba LC, Duan S, Gardner J, Wise C, Miner A, Malloy MJ, Pullinger CR, Kane J, Saccone S, Worthington J, Bruce I, Kwok PY, Menter A, Krueger J, Barton A, Saccone NL, Bowcock AM. A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet. 2008 Mar; 4(3):e1000041. PMID: 18369459; PMCID: PMC2274885.
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    55. Péterfy M, Ben-Zeev O, Mao HZ, Weissglas-Volkov D, Aouizerat BE, Pullinger CR, Frost PH, Kane J, Malloy MJ, Reue K, Pajukanta P, Doolittle MH. Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat Genet. 2007 Dec; 39(12):1483-7. PMID: 17994020.
      View in: PubMed
    56. Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane J, Ellis SG, Tracy RP, Devlin JJ, Psaty BM. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 2008 Jan; 28(1):173-9. PMID: 17975119; PMCID: PMC2636623.
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    57. Bare LA, Morrison AC, Rowland CM, Shiffman D, Luke MM, Iakoubova OA, Kane J, Malloy MJ, Ellis SG, Pankow JS, Willerson JT, Devlin JJ, Boerwinkle E. Five common gene variants identify elevated genetic risk for coronary heart disease. Genet Med. 2007 Oct; 9(10):682-9. PMID: 18073581.
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    58. Leung JM, Sands LP, Wang Y, Poon A, Kwok PY, Kane J, Pullinger CR. Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery. Anesthesiology. 2007 Sep; 107(3):406-11. PMID: 17721242.
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    59. Davidson MH, Smith J, Scott R, Small R, Choi J, Ishida BY, Kane J. Assessment of lipoprotein profiles study (ALPS) and antioxidant activity in healthy subjects treated with AGI-1067. J Clin Lipidol. 2007 Aug; 1(4):271-9. PMID: 21291691.
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    60. Luke MM, Kane J, Liu DM, Rowland CM, Shiffman D, Cassano J, Catanese JJ, Pullinger CR, Leong DU, Arellano AR, Tong CH, Movsesyan I, Naya-Vigne J, Noordhof C, Feric NT, Malloy MJ, Topol EJ, Koschinsky ML, Devlin JJ, Ellis SG. A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease. Arterioscler Thromb Vasc Biol. 2007 Sep; 27(9):2030-6. PMID: 17569884.
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    61. Morrison AC, Bare LA, Chambless LE, Ellis SG, Malloy M, Kane J, Pankow JS, Devlin JJ, Willerson JT, Boerwinkle E. Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. Am J Epidemiol. 2007 Jul 1; 166(1):28-35. PMID: 17443022.
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    62. Wung SF, Kulkarni MV, Pullinger CR, Malloy MJ, Kane J, Aouizerat BE. The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion. Lipids Health Dis. 2006; 5:19. PMID: 16822320; PMCID: PMC1538992.
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    63. Shiffman D, Rowland CM, Louie JZ, Luke MM, Bare LA, Bolonick JI, Young BA, Catanese JJ, Stiggins CF, Pullinger CR, Topol EJ, Malloy MJ, Kane J, Ellis SG, Devlin JJ. Gene variants of VAMP8 and HNRPUL1 are associated with early-onset myocardial infarction. Arterioscler Thromb Vasc Biol. 2006 Jul; 26(7):1613-8. PMID: 16690874.
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    64. Ishida BY, Duncan KG, Bailey KR, Kane J, Schwartz DM. High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture. Br J Ophthalmol. 2006 May; 90(5):616-20. PMID: 16622093; PMCID: PMC1857047.
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    65. Swarbrick MM, Waldenmaier B, Pennacchio LA, Lind DL, Cavazos MM, Geller F, Merriman R, Ustaszewska A, Malloy M, Scherag A, Hsueh WC, Rief W, Mauvais-Jarvis F, Pullinger CR, Kane J, Dent R, McPherson R, Kwok PY, Hinney A, Hebebrand J, Vaisse C. Lack of support for the association between GAD2 polymorphisms and severe human obesity. PLoS Biol. 2005 Sep; 3(9):e315. PMID: 16122350; PMCID: PMC1193520.
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    66. Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane J. Identification of four gene variants associated with myocardial infarction. Am J Hum Genet. 2005 Oct; 77(4):596-605. PMID: 16175505; PMCID: PMC1275608.
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    67. Khovidhunkit W, Hachem JP, Medzihradszky KF, Duchateau PN, Shigenaga JK, Moser AH, Movsesyan I, Naya-Vigne J, Kane J, Feingold KR, Grunfeld C. Parotid secretory protein is an HDL-associated protein with anticandidal activity. Am J Physiol Regul Integr Comp Physiol. 2005 May; 288(5):R1306-15. PMID: 15637169.
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    68. Zellner C, Pullinger CR, Aouizerat BE, Frost PH, Kwok PY, Malloy MJ, Kane J. Variations in human HM74 (GPR109B) and HM74A (GPR109A) niacin receptors. Hum Mutat. 2005 Jan; 25(1):18-21. PMID: 15580557.
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    69. Albert TS, Duchateau PN, Deeb SS, Pullinger CR, Cho MH, Heilbron DC, Malloy MJ, Kane J, Brown BG. Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL. J Lipid Res. 2005 Mar; 46(3):469-74. PMID: 15604524.
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    70. Khovidhunkit W, Duchateau PN, Medzihradszky KF, Moser AH, Naya-Vigne J, Shigenaga JK, Kane J, Grunfeld C, Feingold KR. Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL. Atherosclerosis. 2004 Sep; 176(1):37-44. PMID: 15306172.
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    71. Stoller ML, Meng MV, Abrahams HM, Kane J. The primary stone event: a new hypothesis involving a vascular etiology. J Urol. 2004 May; 171(5):1920-4. PMID: 15076312.
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    72. Ishida BY, Bailey KR, Duncan KG, Chalkley RJ, Burlingame AL, Kane J, Schwartz DM. Regulated expression of apolipoprotein E by human retinal pigment epithelial cells. J Lipid Res. 2004 Feb; 45(2):263-71. PMID: 14594998.
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    73. Huuskonen J, Abedin M, Vishnu M, Pullinger CR, Baranzini SE, Kane J, Fielding PE, Fielding CJ. Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts. Biochem Biophys Res Commun. 2003 Jun 27; 306(2):463-8. PMID: 12804586.
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    74. Aouizerat BE, Kane J. Apolipoprotein A-II: active or passive role in familial combined hyperlipidemia. Circ Res. 2003 Jun 13; 92(11):1179-81. PMID: 12805235.
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    75. Pullinger CR, Kane J, Malloy MJ. Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders. Expert Rev Cardiovasc Ther. 2003 May; 1(1):107-19. PMID: 15030301.
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    76. Aouizerat BE, Kulkarni M, Heilbron D, Drown D, Raskin S, Pullinger CR, Malloy MJ, Kane J. Genetic analysis of a polymorphism in the human apoA-V gene: effect on plasma lipids. J Lipid Res. 2003 Jun; 44(6):1167-73. PMID: 12671030.
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    77. Jafari M, Leaf DA, Macrae H, Kasem J, O'conner P, Pullinger C, Malloy M, Kane J. The effects of physical exercise on plasma prebeta-1 high-density lipoprotein. Metabolism. 2003 Apr; 52(4):437-42. PMID: 12701055.
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    78. Vanhamme L, Paturiaux-Hanocq F, Poelvoorde P, Nolan DP, Lins L, Van Den Abbeele J, Pays A, Tebabi P, Van Xong H, Jacquet A, Moguilevsky N, Dieu M, Kane J, De Baetselier P, Brasseur R, Pays E. Apolipoprotein L-I is the trypanosome lytic factor of human serum. Nature. 2003 Mar 6; 422(6927):83-7. PMID: 12621437.
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    79. Pullinger CR, Eng C, Salen G, Shefer S, Batta AK, Erickson SK, Verhagen A, Rivera CR, Mulvihill SJ, Malloy MJ, Kane J. Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. J Clin Invest. 2002 Jul; 110(1):109-17. PMID: 12093894; PMCID: PMC151029.
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    80. Gaffney D, Pullinger CR, O'Reilly DS, Hoffs MS, Cameron I, Vass JK, Kulkarni MV, Kane J, Schumaker VN, Watts GF, Packard CJ. Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding. Clin Chim Acta. 2002 Jul; 321(1-2):113-21. PMID: 12031600.
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    81. Duncan KG, Bailey KR, Kane J, Schwartz DM. Human retinal pigment epithelial cells express scavenger receptors BI and BII. Biochem Biophys Res Commun. 2002 Apr 12; 292(4):1017-22. PMID: 11944916.
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    82. Kane J. Does hypertriglyceridemia present an indication for pioglitazone therapy in diabetes? Diabetes Technol Ther. 2002; 4(2):153-5. PMID: 12079618.
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    83. Duchateau PN, Pullinger CR, Cho MH, Eng C, Kane J. Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. J Lipid Res. 2001 Apr; 42(4):620-30. PMID: 11290834.
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    84. Malloy MJ, Kane J. A risk factor for atherosclerosis: triglyceride-rich lipoproteins. Adv Intern Med. 2001; 47:111-36. PMID: 11795072.
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    85. Frossard PM, Malloy MJ, Lestringant GG, Kane J. Haplotypes of the human renin gene associated with essential hypertension and stroke. J Hum Hypertens. 2001 Jan; 15(1):49-55. PMID: 11224002.
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    86. Drmanac S, Heilbron DC, Pullinger CR, Jafari M, Gietzen D, Ukrainczyk T, Cho MH, Frost PH, Siradze K, Drmanac RT, Kane J, Malloy MJ. Elevated baseline triglyceride levels modulate effects of HMGCoA reductase inhibitors on plasma lipoproteins. J Cardiovasc Pharmacol Ther. 2001 Jan; 6(1):47-56. PMID: 11452336.
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    87. Mahley RW, Pépin J, Palaoglu KE, Malloy MJ, Kane J, Bersot TP. Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype. J Lipid Res. 2000 Aug; 41(8):1290-301. PMID: 10946017.
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    88. Duchateau PN, Movsesyan I, Yamashita S, Sakai N, Hirano K, Schoenhaus SA, O'Connor-Kearns PM, Spencer SJ, Jaffe RB, Redberg RF, Ishida BY, Matsuzawa Y, Kane J, Malloy MJ. Plasma apolipoprotein L concentrations correlate with plasma triglycerides and cholesterol levels in normolipidemic, hyperlipidemic, and diabetic subjects. J Lipid Res. 2000 Aug; 41(8):1231-6. PMID: 10946010.
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    89. Pullinger CR, Hakamata H, Duchateau PN, Eng C, Aouizerat BE, Cho MH, Fielding CJ, Kane J. Analysis of hABC1 gene 5' end: additional peptide sequence, promoter region, and four polymorphisms. Biochem Biophys Res Commun. 2000 May 10; 271(2):451-5. PMID: 10799318.
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    90. Nishino M, Malloy MJ, Naya-Vigne J, Russell J, Kane J, Redberg RF. Lack of association of lipoprotein(a) levels with coronary calcium deposits in asymptomatic postmenopausal women. J Am Coll Cardiol. 2000 Feb; 35(2):314-20. PMID: 10676675.
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    91. Frossard PM, Lestringant GG, Malloy MJ, Kane J. Human renin gene BglI dimorphism associated with hypertension in two independent populations. Clin Genet. 1999 Dec; 56(6):428-33. PMID: 10665661.
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    92. Frossard PM, Kane J, Malloy MJ, Bener A. Renin gene MboI dimorphism is a discriminator for hypertension in hyperlipidaemic subjects. Hypertens Res. 1999 Nov; 22(4):285-9. PMID: 10580395.
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    93. Cheng S, Grow MA, Pallaud C, Klitz W, Erlich HA, Visvikis S, Chen JJ, Pullinger CR, Malloy MJ, Siest G, Kane J. A multilocus genotyping assay for candidate markers of cardiovascular disease risk. Genome Res. 1999 Oct; 9(10):936-49. PMID: 10523522; PMCID: PMC310821.
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    94. Connor JP, Ferrer K, Kane J, Goldberg JM. Evaluation of Langerhans' cells in the cervical epithelium of women with cervical intraepithelial neoplasia. Gynecol Oncol. 1999 Oct; 75(1):130-5. PMID: 10502439.
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    95. Kane J, Havel RJ. Polymorphism of the lipopolysaccharide receptor (CD14) and myocardial infarction. New evidence for a role of gram-negative bacterial infection? Circulation. 1999 Jun 29; 99(25):3210-2. PMID: 10385489.
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    96. Pullinger CR, Gaffney D, Gutierrez MM, Malloy MJ, Schumaker VN, Packard CJ, Kane J. The apolipoprotein B R3531C mutation. Characteristics of 24 subjects from 9 kindreds. J Lipid Res. 1999 Feb; 40(2):318-27. PMID: 9925662.
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    97. Cheng S, Pallaud C, Grow MA, Scharf SJ, Erlich HA, Klitz W, Pullinger CR, Malloy MJ, Kane J, Siest G, Visvikis S. A multilocus genotyping assay for cardiovascular disease. Clin Chem Lab Med. 1998 Aug; 36(8):561-6. PMID: 9806460.
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    98. O'Connor PM, Zysow BR, Schoenhaus SA, Ishida BY, Kunitake ST, Naya-Vigne JM, Duchateau PN, Redberg RF, Spencer SJ, Mark S, Mazur M, Heilbron DC, Jaffe RB, Malloy MJ, Kane J. Prebeta-1 HDL in plasma of normolipidemic individuals: influences of plasma lipoproteins, age, and gender. J Lipid Res. 1998 Mar; 39(3):670-8. PMID: 9548598.
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    99. Schwartz GG, Oliver MF, Ezekowitz MD, Ganz P, Waters D, Kane J, Texter M, Pressler ML, Black D, Chaitman BR, Olsson AG. Rationale and design of the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study that evaluates atorvastatin in unstable angina pectoris and in non-Q-wave acute myocardial infarction. Am J Cardiol. 1998 Mar 1; 81(5):578-81. PMID: 9514453.
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    100. Malloy MJ, Kane J. Aggressive medical therapy for the prevention and treatment of coronary artery disease. Dis Mon. 1998 Jan; 44(1):1-40. PMID: 9457050.
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    101. Sudhir K, Chou TM, Chatterjee K, Smith EP, Williams TC, Kane J, Malloy MJ, Korach KS, Rubanyi GM. Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. Circulation. 1997 Nov 18; 96(10):3774-7. PMID: 9396482.
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    102. Duchateau PN, Pullinger CR, Orellana RE, Kunitake ST, Naya-Vigne J, O'Connor PM, Malloy MJ, Kane J. Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L. J Biol Chem. 1997 Oct 10; 272(41):25576-82. PMID: 9325276.
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    103. O'Connor PM, Naya-Vigne JM, Duchateau PN, Ishida BY, Mazur M, Schoenhaus SA, Zysow BR, Malloy MJ, Kunitake ST, Kane J. Measurement of prebeta-1 HDL in human plasma by an ultrafiltration-isotope dilution technique. Anal Biochem. 1997 Sep 5; 251(2):234-40. PMID: 9299021.
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    104. Pullinger CR, Malloy MJ, Shahidi AK, Ghassemzadeh M, Duchateau P, Villagomez J, Allaart J, Kane J. A novel apolipoprotein C-III variant, apoC-III(Gln38-->Lys), associated with moderate hypertriglyceridemia in a large kindred of Mexican origin. J Lipid Res. 1997 Sep; 38(9):1833-40. PMID: 9323592.
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    105. Hennessy LK, Kunitake ST, Jarvis M, Hamilton RL, Endeman G, Protter A, Kane J. Isolation of subpopulations of high density lipoproteins: three particle species containing apoE and two species devoid of apoE that have affinity for heparin. J Lipid Res. 1997 Sep; 38(9):1859-68. PMID: 9323595.
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    106. Phillips ML, Pullinger C, Kroes I, Kroes J, Hardman DA, Chen G, Curtiss LK, Gutierrez MM, Kane J, Schumaker VN. A single copy of apolipoprotein B-48 is present on the human chylomicron remnant. J Lipid Res. 1997 Jun; 38(6):1170-7. PMID: 9215545.
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    107. van Antwerpen R, Chen GC, Pullinger CR, Kane J, LaBelle M, Krauss RM, Luna-Chavez C, Forte TM, Gilkey JC. Cryo-electron microscopy of low density lipoprotein and reconstituted discoidal high density lipoprotein: imaging of the apolipoprotein moiety. J Lipid Res. 1997 Apr; 38(4):659-69. PMID: 9144081.
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    108. Malloy MJ, Kane J. Aggressive medical therapy for the prevention and treatment of coronary artery disease. Adv Intern Med. 1997; 42:1-38. PMID: 9048115.
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    109. Pullinger CR, Love JA, Liu W, Hennessy LK, Ghassemzadeh M, Newcomb KC, Illingworth DR, Kane J. The apolipoprotein B Q3405E polymorphism has no effect on its low-density-lipoprotein receptor binding affinity. Hum Genet. 1996 Dec; 98(6):678-80. PMID: 8931699.
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    110. Hausmann D, Johnson JA, Sudhir K, Mullen WL, Friedrich G, Fitzgerald PJ, Chou TM, Ports TA, Kane J, Malloy MJ, Yock PG. Angiographically silent atherosclerosis detected by intravascular ultrasound in patients with familial hypercholesterolemia and familial combined hyperlipidemia: correlation with high density lipoproteins. J Am Coll Cardiol. 1996 Jun; 27(7):1562-70. PMID: 8636537.
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    111. Chatterton JE, Schlapfer P, Bütler E, Gutierrez MM, Puppione DL, Pullinger CR, Kane J, Curtiss LK, Schumaker VN. Identification of apolipoprotein B100 polymorphisms that affect low-density lipoprotein metabolism: description of a new approach involving monoclonal antibodies and dynamic light scattering. Biochemistry. 1995 Jul 25; 34(29):9571-80. PMID: 7626627.
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    112. Read TE, Grunfeld C, Kumwenda ZL, Calhoun MC, Kane J, Feingold KR, Rapp JH. Triglyceride-rich lipoproteins prevent septic death in rats. J Exp Med. 1995 Jul 1; 182(1):267-72. PMID: 7790821; PMCID: PMC2192094.
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    113. Pullinger CR, Hennessy LK, Chatterton JE, Liu W, Love JA, Mendel CM, Frost PH, Malloy MJ, Schumaker VN, Kane J. Familial ligand-defective apolipoprotein B. Identification of a new mutation that decreases LDL receptor binding affinity. J Clin Invest. 1995 Mar; 95(3):1225-34. PMID: 7883971; PMCID: PMC441461.
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    114. Sudhir K, Ports TA, Amidon TM, Goldberger JJ, Bhushan V, Kane J, Yock P, Malloy MJ. Increased prevalence of coronary ectasia in heterozygous familial hypercholesterolemia. Circulation. 1995 Mar 1; 91(5):1375-80. PMID: 7867176.
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    115. Insull W, Davidson MH, Demke DM, Dujovne CA, Eckert SM, Ginsberg D, Goldberg AC, Hodis HN, Hughes TA, Kane J. The effects of colestipol tablets compared with colestipol granules on plasma cholesterol and other lipids in moderately hypercholesterolemic patients. Atherosclerosis. 1995 Jan 20; 112(2):223-35. PMID: 7772081.
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    116. Read TE, Grunfeld C, Kumwenda Z, Calhoun MC, Kane J, Feingold KR, Rapp JH. Triglyceride-rich lipoproteins improve survival when given after endotoxin in rats. Surgery. 1995 Jan; 117(1):62-7. PMID: 7809838.
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    117. Rapp JH, Lespine A, Hamilton RL, Colyvas N, Chaumeton AH, Tweedie-Hardman J, Kotite L, Kunitake ST, Havel RJ, Kane J. Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. Arterioscler Thromb. 1994 Nov; 14(11):1767-74. PMID: 7947602.
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    118. Wurfel MM, Kunitake ST, Lichenstein H, Kane J, Wright SD. Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J Exp Med. 1994 Sep 1; 180(3):1025-35. PMID: 8064223; PMCID: PMC2191628.
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    119. Zysow BR, Pullinger CR, Hennessy LK, Farese RV, Ghassemzadeh M, Kane J. The apolipoprotein C-II variant apoC-IILys19-->Thr is not associated with dyslipidemia in an affected kindred. Clin Genet. 1994 Jun; 45(6):292-7. PMID: 7923858.
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    120. Kunitake ST, Carilli CT, Lau K, Protter AA, Naya-Vigne J, Kane J. Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption. Biochemistry. 1994 Mar 1; 33(8):1988-93. PMID: 8117655.
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    121. Malloy MJ, Kane J. Medical management of hyperlipidemic states. Adv Intern Med. 1994; 39:603-31. PMID: 8140966.
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    122. Read TE, Harris HW, Grunfeld C, Feingold KR, Kane J, Rapp JH. The protective effect of serum lipoproteins against bacterial lipopolysaccharide. Eur Heart J. 1993 Dec; 14 Suppl K:125-9. PMID: 8131781.
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    123. Read TE, Harris HW, Grunfeld C, Feingold KR, Calhoun MC, Kane J, Rapp JH. Chylomicrons enhance endotoxin excretion in bile. Infect Immun. 1993 Aug; 61(8):3496-502. PMID: 8335381; PMCID: PMC281028.
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    124. Bhushan V, Malloy MJ, Engler MM, Engler MB, Drown D, Kane J. Exploratory data analysis of hyperlipidemia on the Macintosh: software tools for analysis of biochemical, clinical, and genetic variables in 1677 consecutive lipid clinic patients. J Med Syst. 1993 Aug; 17(3-4):187-93. PMID: 8254263.
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    125. Hennessy LK, Kunitake ST, Kane J. Apolipoprotein A-I-containing lipoproteins, with or without apolipoprotein A-II, as progenitors of pre-beta high-density lipoprotein particles. Biochemistry. 1993 Jun 8; 32(22):5759-65. PMID: 8504094.
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    126. Harris HW, Grunfeld C, Feingold KR, Read TE, Kane J, Jones AL, Eichbaum EB, Bland GF, Rapp JH. Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. J Clin Invest. 1993 Mar; 91(3):1028-34. PMID: 8450032; PMCID: PMC288056.
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    127. Pullinger CR, Zysow BR, Hennessy LK, Frost PH, Malloy MJ, Kane J. Molecular cloning and characteristics of a new apolipoprotein C-II mutant identified in three unrelated individuals with hypercholesterolemia and hypertriglyceridemia. Hum Mol Genet. 1993 Jan; 2(1):69-74. PMID: 8490626.
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    128. Kunitake ST, Jarvis MR, Hamilton RL, Kane J. Binding of transition metals by apolipoprotein A-I-containing plasma lipoproteins: inhibition of oxidation of low density lipoproteins. Proc Natl Acad Sci U S A. 1992 Aug 1; 89(15):6993-7. PMID: 1495991; PMCID: PMC49631.
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    129. Pullinger CR, Hillas E, Hardman DA, Chen GC, Naya-Vigne JM, Iwasa JA, Hamilton RL, Lalouel JM, Williams RR, Kane J. Two apolipoprotein B gene defects in a kindred with hypobetalipoproteinemia, one of which results in a truncated variant, apoB-61, in VLDL and LDL. J Lipid Res. 1992 May; 33(5):699-710. PMID: 1619363.
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    130. Zysow BR, Pullinger CR, Kane J. A polymorphic PstI site in intron 2 of the human apolipoprotein C-II gene detected by polymerase chain reaction. Hum Genet. 1992 May; 89(3):361. PMID: 1351041.
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    131. Colyvas N, Rapp JH, Phillips NR, Stoney R, Perez S, Kane J, Havel RJ. Relation of plasma lipid and apoprotein levels to progressive intimal hyperplasia after arterial endarterectomy. Circulation. 1992 Apr; 85(4):1286-92. PMID: 1555272.
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    132. Malloy MJ, Kane J. Drs malloy and kane respond. West J Med. 1992 Feb; 156(2):209. PMID: 18750862.
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    133. Hardman DA, Pullinger CR, Hamilton RL, Kane J, Malloy MJ. Molecular and metabolic basis for the metabolic disorder normotriglyceridemic abetalipoproteinemia. J Clin Invest. 1991 Nov; 88(5):1722-9. PMID: 1939657; PMCID: PMC295713.
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    134. Eichbaum EB, Harris HW, Kane J, Rapp JH. Chylomicrons can inhibit endotoxin activity in vitro. J Surg Res. 1991 Nov; 51(5):413-6. PMID: 1758174.
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    135. Malloy MJ, Frost PH, Kane J. Niacin--the long and the short of it. West J Med. 1991 Oct; 155(4):424-6. PMID: 1771892; PMCID: PMC1003039.
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    136. Harris HW, Eichbaum EB, Kane J, Rapp JH. Detection of endotoxin in triglyceride-rich lipoproteins in vitro. J Lab Clin Med. 1991 Aug; 118(2):186-93. PMID: 1856581.
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    137. Chen GC, Lau K, Hamilton RL, Kane J. Differences in local conformation in human apolipoprotein B-100 of plasma low density and very low density lipoproteins as identified by cathepsin D. J Biol Chem. 1991 Jul 5; 266(19):12581-7. PMID: 2061328.
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    138. Ameis D, Kobayashi J, Davis RC, Ben-Zeev O, Malloy MJ, Kane J, Lee G, Wong H, Havel RJ, Schotz MC. Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene. J Clin Invest. 1991 Apr; 87(4):1165-70. PMID: 2010533; PMCID: PMC295125.
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    139. Wardell MR, Rall SC, Schaefer EJ, Kane J, Weisgraber KH. Two apolipoprotein E5 variants illustrate the importance of the position of additional positive charge on receptor-binding activity. J Lipid Res. 1991 Mar; 32(3):521-8. PMID: 1648586.
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    140. Kane J, Malloy MJ, Ports TA, Phillips NR, Diehl JC, Havel RJ. Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens. JAMA. 1990 Dec 19; 264(23):3007-12. PMID: 2243428.
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    141. Kunitake ST, Young SG, Chen GC, Pullinger CR, Zhu S, Pease RJ, Scott J, Hass P, Schilling J, Kane J. Conformation of apolipoprotein B-100 in the low density lipoproteins of tangier disease. Identification of localized conformational response to triglyceride content. J Biol Chem. 1990 Dec 5; 265(34):20739-46. PMID: 1701170.
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    142. Kane J, Malloy MJ. Treatment of hyperlipidemia. Annu Rev Med. 1990; 41:471-82. PMID: 2184745.
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    143. Kunitake ST, Chen GC, Kung SF, Schilling JW, Hardman DA, Kane J. Pre-beta high density lipoprotein. Unique disposition of apolipoprotein A-I increases susceptibility to proteolysis. Arteriosclerosis. 1990 Jan-Feb; 10(1):25-30. PMID: 2136993.
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    144. Chen GC, Zhu S, Hardman DA, Schilling JW, Lau K, Kane J. Structural domains of human apolipoprotein B-100. Differential accessibility to limited proteolysis of B-100 in low density and very low density lipoproteins. J Biol Chem. 1989 Aug 25; 264(24):14369-75. PMID: 2668286.
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    145. Chen GC, Hardman DA, Hamilton RL, Mendel CM, Schilling JW, Zhu S, Lau K, Wong JS, Kane J. Distribution of lipid-binding regions in human apolipoprotein B-100. Biochemistry. 1989 Mar 21; 28(6):2477-84. PMID: 2730877.
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    146. Rapp JH, Harris HW, Hamilton RL, Krupski WC, Reilly LM, Ehrenfeld WK, Stoney RJ, Goldstone J, Kane J. Particle size distribution of lipoproteins from human atherosclerotic plaque: a preliminary report. J Vasc Surg. 1989 Jan; 9(1):81-8. PMID: 2911145.
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    147. Sernatinger J, Hoffman A, Hardman D, Kane J, Levy JA. Neutralization of mouse xenotropic virus by lipoproteins involves binding to the virions. J Gen Virol. 1988 Oct; 69 ( Pt 10):2657-61. PMID: 2844973.
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    148. Mendel CM, Kunitake ST, Hong K, Erickson SK, Kane J, Kempner ES. Radiation inactivation of binding sites for high-density lipoproteins in human liver membranes. Biochim Biophys Acta. 1988 Jul 22; 961(2):188-93. PMID: 2839235.
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    149. Coleman RT, Cawthon RM, Malloy MJ, Kane J, Nakashima PF, Frossard PM. Bsm I RFLP at the human apolipoprotein AI-CIII gene complex locus. Nucleic Acids Res. 1988 Mar 25; 16(5):2364. PMID: 2895918; PMCID: PMC338250.
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    150. Coleman RT, Malloy MJ, Kane J, Frossard PM. NcoI dimorphic site located 8kb 3' to the human apolipoprotein AIV (APOA4) gene. Nucleic Acids Res. 1988 Feb 11; 16(3):1222. PMID: 2894008; PMCID: PMC334771.
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    151. Gustafson A, Kane J, Havel RJ. Determinants of kallikrein proteolysis of apolipoprotein B-100 in human blood plasma. Eur J Clin Invest. 1988 Feb; 18(1):75-80. PMID: 3130263.
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    152. Mendel CM, Kunitake ST, Kane J, Kempner ES. Radiation inactivation of binding sites for high density lipoproteins in human fibroblast membranes. J Biol Chem. 1988 Jan 25; 263(3):1314-9. PMID: 2826475.
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    153. Kane J, Malloy MJ. When to treat hyperlipidemia. Adv Intern Med. 1988; 33:143-63. PMID: 3278503.
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    154. Hardman DA, Protter AA, Schilling JW, Kane J. Carboxyl terminal analysis of human B-48 protein confirms the novel mechanism proposed for chain termination. Biochem Biophys Res Commun. 1987 Dec 31; 149(3):1214-9. PMID: 3426612.
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    155. Malloy MJ, Kane J, Kunitake ST, Tun P. Complementarity of colestipol, niacin, and lovastatin in treatment of severe familial hypercholesterolemia. Ann Intern Med. 1987 Nov; 107(5):616-23. PMID: 3662275.
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    156. Frossard PM, Coleman RT, Malloy MJ, Kane J, Levy-Wilson B, Appleby VA. Human apolipoprotein CI (apoC1) gene locus: DraI dimorphic site. Nucleic Acids Res. 1987 Feb 25; 15(4):1884. PMID: 2881281; PMCID: PMC340600.
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    157. Frossard PM, Lim DW, Coleman RT, Funke H, Assmann G, Malloy MJ, Kane J. Human apolipoprotein CI (ApoC1) gene locus: BglI dimorphic site. Nucleic Acids Res. 1987 Feb 11; 15(3):1344. PMID: 2881271; PMCID: PMC340542.
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    158. Frossard PM, Coleman RT, Dillan NA, Lim DW, Malloy MJ, Kane J, Funke H, Assmann G. DraI RFLP in the human apolipoprotein AI-CIII-AIV gene complex. Nucleic Acids Res. 1986 Nov 11; 14(21):8699. PMID: 2878415; PMCID: PMC311899.
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    159. Coleman RT, Dillan NA, Lim DW, Malloy MJ, Kane J, Frossard PM. TaqI and XbaI RFLPs detected with a human apo IV (Apo4) cDNA probe. Nucleic Acids Res. 1986 Oct 10; 14(19):7818. PMID: 2877436; PMCID: PMC311808.
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    160. Stalenhoef AF, Malloy MJ, Kane J, Havel RJ. Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in patients with familial dysbetalipoproteinemia. J Clin Invest. 1986 Sep; 78(3):722-8. PMID: 3745433; PMCID: PMC423660.
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    161. Protter AA, Hardman DA, Sato KY, Schilling JW, Yamanaka M, Hort YJ, Hjerrild KA, Chen GC, Kane J. Analysis of cDNA clones encoding the entire B-26 region of human apolipoprotein B. Proc Natl Acad Sci U S A. 1986 Aug; 83(15):5678-82. PMID: 3461454; PMCID: PMC386352.
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    162. Hardman DA, Gustafson A, Schilling JW, Donaldson VH, Kane J. Scission of human apolipoprotein B-100 by kallikrein: characterization of the cleavage site. Biochem Biophys Res Commun. 1986 Jun 13; 137(2):821-5. PMID: 3637099.
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    163. Menzel HJ, Kane J, Malloy MJ, Havel RJ. A variant primary structure of apolipoprotein C-II in individuals of African descent. J Clin Invest. 1986 Feb; 77(2):595-601. PMID: 3944271; PMCID: PMC423392.
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    164. Mendel CM, Kunitake ST, Kane J. Discrimination between subclasses of human high-density lipoproteins by the HDL binding sites of bovine liver. Biochim Biophys Acta. 1986 Jan 3; 875(1):59-68. PMID: 3000454.
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    165. Kane J, Havel RJ. Treatment of hypercholesterolemia. Annu Rev Med. 1986; 37:427-35. PMID: 3518611.
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    166. Kane J. Speciation of HDL. Adv Exp Med Biol. 1986; 201:29-35. PMID: 3541521.
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    167. Kunitake ST, La Sala KJ, Kane J. Apolipoprotein A-I-containing lipoproteins with pre-beta electrophoretic mobility. J Lipid Res. 1985 May; 26(5):549-55. PMID: 3926924.
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    168. Chen GC, Guo LS, Hamilton RL, Gordon V, Richards EG, Kane J. Circular dichroic spectra of apolipoprotein E in model complexes and cholesterol-rich lipoproteins: lipid contribution. Biochemistry. 1984 Dec 18; 23(26):6530-8. PMID: 6529567.
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    169. Chen GC, Kane J, Hamilton RL. Thermal behavior of cores of human serum triglyceride-rich lipoproteins: a study of induced circular dichroism of beta-carotene. Biochemistry. 1984 Mar 13; 23(6):1119-24. PMID: 6712939.
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    170. Stalenhoef AF, Malloy MJ, Kane J, Havel RJ. Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in normal and lipoprotein lipase-deficient humans. Proc Natl Acad Sci U S A. 1984 Mar; 81(6):1839-43. PMID: 6584917; PMCID: PMC345017.
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    171. McVicar JP, Kunitake ST, Hamilton RL, Kane J. Characteristics of human lipoproteins isolated by selected-affinity immunosorption of apolipoprotein A-I. Proc Natl Acad Sci U S A. 1984 Mar; 81(5):1356-60. PMID: 6424116; PMCID: PMC344832.
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    172. Phillips NR, Havel RJ, Kane J. Sex-related differences in the concentrations of apolipoprotein E in human blood plasma and plasma lipoproteins. J Lipid Res. 1983 Nov; 24(11):1525-31. PMID: 6655368.
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    173. Hornick CA, Kita T, Hamilton RL, Kane J, Havel RJ. Secretion of lipoproteins from the liver of normal and Watanabe heritable hyperlipidemic rabbits. Proc Natl Acad Sci U S A. 1983 Oct; 80(19):6096-100. PMID: 6577469; PMCID: PMC534367.
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    174. Davis PA, Forte TM, Kane J, Hardman DA, Krauss RM, Blum CB. Apolipoprotein and size heterogeneity in human umbilical cord blood low density lipoproteins. Biochim Biophys Acta. 1983 Sep 20; 753(2):186-94. PMID: 6615856.
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    175. Havel RJ, Kotite L, Kane J, Tun P, Bersot T. Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3. J Clin Invest. 1983 Jul; 72(1):379-87. PMID: 6860421; PMCID: PMC1129193.
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    176. Fielding PE, Fielding CJ, Havel RJ, Kane J, Tun P. Cholesterol net transport, esterification, and transfer in human hyperlipidemic plasma. J Clin Invest. 1983 Mar; 71(3):449-60. PMID: 6826717; PMCID: PMC436892.
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    177. Kane J, Chen GC, Hamilton RL, Hardman DA, Malloy MJ, Havel RJ. Remnants of lipoproteins of intestinal and hepatic origin in familial dysbetalipoproteinemia. Arteriosclerosis. 1983 Jan-Feb; 3(1):47-56. PMID: 6824496.
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    178. Kane J. Apolipoprotein B: structural and metabolic heterogeneity. Annu Rev Physiol. 1983; 45:637-50. PMID: 6342527.
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    179. Havel RJ, Kita T, Kotite L, Kane J, Hamilton RL, Goldstein JL, Brown MS. Concentration and composition of lipoproteins in blood plasma of the WHHL rabbit. An animal model of human familial hypercholesterolemia. Arteriosclerosis. 1982 Nov-Dec; 2(6):467-74. PMID: 6960858.
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    180. Phillips NR, Havel RJ, Kane J. Serum apolipoprotein A-I levels: relationship to lipoprotein lipid levels and selected demographic variables. Am J Epidemiol. 1982 Aug; 116(2):302-13. PMID: 6810694.
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    181. Kunitake ST, Kane J. Factors affecting the integrity of high density lipoproteins in the ultracentrifuge. J Lipid Res. 1982 Aug; 23(6):936-40. PMID: 6813413.
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    182. Guo LS, Hamilton RL, Kane J, Fielding CJ, Chen GC. Characterization and quantitation of apolipoproteins A-I and E of normal and cholesterol-fed guinea pigs. J Lipid Res. 1982 May; 23(4):531-42. PMID: 7182951.
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    183. Malloy MJ, Kane J. Hypolipidemia. Med Clin North Am. 1982 Mar; 66(2):469-84. PMID: 7040848.
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    184. Kane J, Malloy MJ. Treatment of hypercholesterolemia. Med Clin North Am. 1982 Mar; 66(2):537-50. PMID: 7040850.
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    185. Havel RJ, Kane J. Therapy of hyperlipidemic states. Annu Rev Med. 1982; 33:417-33. PMID: 7044276.
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    186. Van't Hooft FM, Hardman DA, Kane J, Havel RJ. Apolipoprotein B (B-48) of rat chylomicrons is not a precursor of the apolipoprotein of low density lipoproteins. Proc Natl Acad Sci U S A. 1982 Jan; 79(1):179-82. PMID: 6948299; PMCID: PMC345686.
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    187. Schneider WJ, Kovanen PT, Brown MS, Goldstein JL, Utermann G, Weber W, Havel RJ, Kotite L, Kane J, Innerarity TL, Mahley RW. Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows. J Clin Invest. 1981 Oct; 68(4):1075-85. PMID: 6270194; PMCID: PMC370895.
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    188. Malloy MJ, Kane J, Hardman DA, Hamilton RL, Dalal KB. Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein. J Clin Invest. 1981 May; 67(5):1441-50. PMID: 7229035; PMCID: PMC370711.
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    189. Kane J, Malloy MJ, Tun P, Phillips NR, Freedman DD, Williams ML, Rowe JS, Havel RJ. Normalization of low-density-lipoprotein levels in heterozygous familial hypercholesterolemia with a combined drug regimen. N Engl J Med. 1981 Jan 29; 304(5):251-8. PMID: 7003391.
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    190. Phillips NR, Havel RJ, Kane J. Levels and interrelationships of serum and lipoprotein cholesterol and triglycerides. Association with adiposity and the consumption of ethanol, tobacco, and beverages containing caffeine. Arteriosclerosis. 1981 Jan-Feb; 1(1):13-24. PMID: 7295182.
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    191. Havel RJ, Kotite L, Vigne JL, Kane J, Tun P, Phillips N, Chen GC. Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency. J Clin Invest. 1980 Dec; 66(6):1351-62. PMID: 7440719; PMCID: PMC371621.
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    192. Polz E, Kotite L, Havel RJ, Kane J, Sata T. Human apolipoprotein C-I: concentration in blood serum and lipoproteins. Biochem Med. 1980 Dec; 24(3):229-37. PMID: 7283981.
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    193. Chen GC, Krieger M, Kane J, Wu CS, Brown MS, Goldstein JL. beta-Carotene as a probe of lipid domains of reconstituted human plasma low-density lipoprotein: induced circular dichroism. Biochemistry. 1980 Sep 30; 19(20):4706-12. PMID: 7426623.
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    194. Tan MH, Havel RJ, Gerich JE, Soeldner JS, Kane J. Pancreatic alpha and beta cell function in familial dysbetalipoproteinemia. Horm Metab Res. 1980 Sep; 12(9):421-5. PMID: 7000652.
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    195. Kane J, Hardman DA, Paulus HE. Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons. Proc Natl Acad Sci U S A. 1980 May; 77(5):2465-9. PMID: 6930644; PMCID: PMC349420.
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    196. Kane J, Hardman DA, Dimpfl JC, Levy JA. Apolipoprotein is responsible for neutralization of xenotropic type C virus by mouse serum. Proc Natl Acad Sci U S A. 1979 Nov; 76(11):5957-61. PMID: 230495; PMCID: PMC411772.
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    197. Chen GC, Kane J. Secondary structure in very low density and intermediate density lipoproteins of human serum. J Lipid Res. 1979 May; 20(4):481-8. PMID: 222856.
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    198. Abrams JJ, Grundy SM, Kane J, Chang CM. Normocholesterolemic dysbetalipoproteinemia with xanthomatosis. Metabolism. 1979 Feb; 28(2):113-24. PMID: 216881.
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    199. Havel RJ, Kotite L, Kane J. Isoelectric heterogeneity of the cofactor protein for lipoprotein lipase in human blood plasma. Biochem Med. 1979 Feb; 21(1):121-38. PMID: 222259.
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    200. Lie-Injo LE, Randhawa ZI, Kane J, Ganesan J, George R. Heterogeneity of hemoglobin gamma chains in normal newborns and in cases of alpha and beta thalassemia. Am J Hematol. 1979; 6(1):17-25. PMID: 453194.
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    201. Kunitake ST, Loh E, Schumaker VN, Ma SK, Knobler CM, Kane J, Hamilton RL. Molecular weight distributions of polydisperse systems: application to very low density lipoproteins. Biochemistry. 1978 May 16; 17(10):1936-42. PMID: 207303.
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    202. Malloy MJ, Kane J, Rowe JS. Familial hypercholesterolemia in children: treatment with p-aminosalicylic acid. Pediatrics. 1978 Mar; 61(3):365-72. PMID: 205828.
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    203. Kaufman JM, Fam B, Jacobs SC, Gabilondo F, Yalla S, Kane J, Rossier AB. Bladder cancer and squamous metaplasia in spinal cord injury patients. J Urol. 1977 Dec; 118(6):967-71. PMID: 926277.
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    204. Pagnan A, Havel RJ, Kane J, Kotite L. Characterization of human very low density lipoproteins containing two electrophoretic populations: double pre-beta lipoproteinemia and primary dysbetalipoproteinemia. J Lipid Res. 1977 Sep; 18(5):613-22. PMID: 198504.
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    205. Lie-Injo LE, Ganesan J, Randhawa ZI, Peterson D, Kane J. Hb Leiden-beta (0) thalassemia in a Chinese with severe hemolytic anemia. Am J Hematol. 1977; 2(4):335-42. PMID: 602924.
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    206. Sata T, Havel RJ, Kotite L, Kane J. New protein in human blood plasma, rich in proline, with lipid-binding properties. Proc Natl Acad Sci U S A. 1976 Apr; 73(4):1063-7. PMID: 1063389; PMCID: PMC430200.
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    207. Wolfe BM, Havel JR, Marliss EB, Kane J, Seymour J, Ahuja SP. Effects of a 3-day fast and of ethanol on splanchnic metabolism of FFA, amino acids, and carbohydrates in healthy young men. J Clin Invest. 1976 Feb; 57(2):329-40. PMID: 176179; PMCID: PMC436657.
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    208. Kane J, Sata T, Hamilton RL, Havel RJ. Apoprotein composition of very low density lipoproteins of human serum. J Clin Invest. 1975 Dec; 56(6):1622-34. PMID: 172534; PMCID: PMC333142.
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    209. Havel RJ, Kane J. Quantification of triglyceride transport in blood plasma: a critical analysis. Fed Proc. 1975 Dec; 34(13):2250-7. PMID: 172371.
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    210. Faergeman O, Sata T, Kane J, Havel RJ. Metabolism of apoprotein B of plasma very low density lipoproteins in the rat. J Clin Invest. 1975 Dec; 56(6):1396-1403. PMID: 172530; PMCID: PMC333117.
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    211. Chapman MJ, Kane J. Stability of the apoprotein of human serum low density lipoprotein: absence of endogenous endopeptidase activity. Biochem Biophys Res Commun. 1975 Oct 6; 66(3):1030-6. PMID: 170935.
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    212. Linscott WD, Kane J. The complement system in cryoglobulinaemia. Interaction with immunoglobulins and lipoproteins. Clin Exp Immunol. 1975 Sep; 21(3):510-9. PMID: 173488; PMCID: PMC1538309.
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    213. Chen GC, Kane J. Temperature dependence of the optical activity of human serum low density lipoprotein. The role of lipids. Biochemistry. 1975 Jul 29; 14(15):3357-62. PMID: 167825.
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    214. Kane J, Malloy MJ. Editorial: Early prevention of atherosclerosis. West J Med. 1975 Apr; 122(4):328-9. PMID: 1154774; PMCID: PMC1129734.
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    215. Chen GC, Kane J. Contribution of carotenoids to the optical activity of human serum low-density lipoprotein. Biochemistry. 1974 Jul 30; 13(16):3330-5. PMID: 4366472.
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    216. Wolfe BM, Kane J, Havel RJ, Brewster HP. Mechanism of the hypolipemic effect of clofibrate in postabsorptive man. J Clin Invest. 1973 Sep; 52(9):2146-59. PMID: 4353773; PMCID: PMC333015.
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    217. Havel RJ, Kane J. Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in triglyceride-rich lipoproteins. Proc Natl Acad Sci U S A. 1973 Jul; 70(7):2015-9. PMID: 4352966; PMCID: PMC433655.
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    218. Kane J. A rapid electrophoretic technique for identification of subunit species of apoproteins in serum lipoproteins. Anal Biochem. 1973 Jun; 53(2):350-64. PMID: 4351944.
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    219. Havel RJ, Kane J, Kashyap ML. Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man. J Clin Invest. 1973 Jan; 52(1):32-8. PMID: 4345202; PMCID: PMC302224.
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    220. Havel RJ, Kane J. Drugs and lipid metabolism. Annu Rev Pharmacol. 1973; 13:287-308. PMID: 4576891.
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    221. Hamilton RL, Havel RJ, Kane J, Blaurock AE, Sata T. Cholestasis: lamellar structure of the abnormal human serum lipoprotein. Science. 1971 Apr 30; 172(3982):475-8. PMID: 5550502.
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    222. Havel RJ, Kane J, Balasse EO, Segel N, Basso LV. Splanchnic metabolism of free fatty acids and production of triglycerides of very low density lipoproteins in normotriglyceridemic and hypertriglyceridemic humans. J Clin Invest. 1970 Nov; 49(11):2017-35. PMID: 5475985; PMCID: PMC535780.
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    223. Kane J, Richards EG, Havel RJ. Subunit heterogeneity in human serum beta lipoprotein. Proc Natl Acad Sci U S A. 1970 Aug; 66(4):1075-82. PMID: 4990876; PMCID: PMC335788.
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    224. Havel RJ, Balasse EO, Williams HE, Kane J, Segel N. Splanchnic metabolism in von Gierke's disease (glycogenosis type I). Trans Assoc Am Physicians. 1969; 82:305-23. PMID: 5375154.
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    225. KANE JP, LONGCOPE C, PAVLATOS FC, GRODSKY GM. STUDIES OF CARBOHYDRATE METABOLISM IN IDIOPATHIC HYPERTRIGLYCERIDEMIA. Metabolism. 1965 Apr; 14:471-86. PMID: 14288605.
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    226. KANE JP, FORSHAM PH. Sterol biosynthesis under the influence of a thyroxine analog (3,5-diiodothyroacetic acid). Metabolism. 1962 Dec; 11:1310-4. PMID: 13962187.
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