John Kane, MD, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address555 Mission Bay Blvd South
San Francisco CA 94158
Phone415-476-2241
ORCID ORCID Icon0000-0001-8049-3850 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPh.D.1971 Graduate Division (Biochemistry)

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Developing Strategies to Reduce DUP in the Age of Social Medial and the Internet
    NIH R34MH103835Aug 1, 2014 - Jun 30, 2016
    Role: Principal Investigator
    Early Phase Psychosis: Informing Treatment Decisions
    NIH P30MH090590Jul 27, 2010 - Apr 30, 2015
    Role: Principal Investigator
    Dissecting Heterogeneity of Treatment Response of First Episode Schizophrenia
    NIH P50MH080173May 9, 2008 - Apr 30, 2014
    Role: Principal Investigator
    Relapse Prevention Study: Steering and Implementation
    NIH U01MH070023Feb 1, 2006 - Dec 31, 2011
    Role: Principal Investigator
    Early Phase Schizophrenia: Optimizing Outcomes
    NIH P30MH074543Sep 28, 2005 - Jun 30, 2010
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR018535Jul 1, 2003 - Mar 31, 2012
    Role: Co-Investigator
    Treating Refractory Childhood Schizophrenia
    NIH R01MH060229Sep 1, 2001 - Jul 31, 2007
    Role: Principal Investigator
    COURSE OF ILLNESS IN SCHIZOPHRENIA: OPTIMIZING OUTCOMES
    NIH P30MH060575Feb 18, 2000 - Jan 31, 2006
    Role: Principal Investigator
    Preventing Morbidity in First Episode Schizophrenia
    NIH R01MH060004Sep 30, 1998 - Jun 30, 2010
    Role: Principal Investigator
    SPECIATION OF HDL AND LDL
    NIH R01HL050782Apr 1, 1994 - Mar 31, 1999
    Role: Principal Investigator
    NEW ANTIPSYCHOTICS--CLINICAL TRIALS AND FOLLOWUP
    NIH R01MH046633Apr 1, 1992 - Mar 31, 1999
    Role: Principal Investigator
    SCIENTIFIC AND TECHNICAL EVALUATION AWARD
    NIH U09MH049952Jan 15, 1992 - Oct 31, 1993
    Role: Principal Investigator
    TREATMENT OF NEUROLEPTIC NONRESPONSIVE SCHIZOPHRENIA
    NIH R01MH042929Aug 1, 1987 - Jul 31, 1992
    Role: Principal Investigator
    STUDY OF SCHIZOPHRENIA
    NIH P30MH041960Sep 25, 1986 - Dec 31, 1999
    Role: Principal Investigator
    CLINICAL RESEARCH CENTER FOR THE STUDY OF SCHIZOPHRENIA
    NIH P50MH041960Sep 25, 1986 - Dec 31, 1996
    Role: Principal Investigator
    PROSPECTIVE STUDY OF TARDIVE DYSKINESIA IN THE ELDERLY
    NIH R01MH040015Mar 1, 1986 - Nov 30, 1995
    Role: Principal Investigator
    TREATMENT STRATEGIES IN SCHIZOPHRENIA
    NIH U10MH039992Sep 20, 1984 - Aug 31, 1993
    Role: Principal Investigator
    High-Density Lipoprotein Species--Structures and Roles
    NIH R01HL031210Jul 1, 1984 - Aug 31, 2007
    Role: Principal Investigator
    LITHIUM LEVELS AND NEUROLEPTICS IN BIPOLAR ILLNESS
    NIH R01MH037576Sep 24, 1982 - Aug 31, 1988
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    PROSPECTIVE STUDY OF TARDIVE DYSKINESIA DEVELOPMENT
    NIH R01MH032369Mar 1, 1979 - Mar 31, 2004
    Role: Principal Investigator
    PROSPECTIVE STUDY OF TARDIVE DYSKINESIA DEVELOPMENT
    NIH R37MH032369Mar 1, 1979 - Mar 31, 1998
    Role: Principal Investigator
    SCOR IN ARTERIOSCLEROSIS
    NIH P50HL014237Dec 1, 1976 - Nov 30, 1997
    Role: Co-Investigator
    General Clinical Research Center
    NIH M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Structural variation across 138,134 samples in the TOPMed consortium. Res Sq. 2023 Feb 03. Jun G, English A, Metcalf G, Yang J, Chaisson M, Pankratz N, Menon V, Salerno W, Krasheninina O, Smith A, Lane J, Blackwell T, Kang HM, Salvi S, Meng Q, Shen H, Pasham D, Bhamidipati S, Kottapalli K, Arnett D, Ashley-Koch A, Auer P, Beutel K, Bis J, Blangero J, Bowden D, Brody J, Cade B, Chen YI, Cho M, Curran J, Fornage M, Frredman B, Fingerlin T, Gelb B, Hou L, Hung YJ, Kane JP, Kaplan R, Kim W, Loos R, Marcus G, Mathias R, McGarvey S, Montgomery C, Naseri T, Nouraie S, Preuss M, Palmer N, Peyser P, Raffield L, Ratan A, Redline S, Reupena M, Rotter J, Rich S, Rienstra M, Ruczinski I, Sankaran V, Schwartz D, Seidman C, Seidman J, Silverman E, Smith J, Stilp A, Taylor K, Telen M, Weiss S, Williams LK, Wu B, Yanek L, Zhang Y, Lasky-Su J, Gingras MC, Dutcher S, Eichler E, Gabriel S, Germer S, Kim R, Martinez K, Nickerson D, Luo J, Reiner A, Gibbs R, Boerwinkle E, Abecasis G, Sedlazeck F. PMID: 36778386; PMCID: PMC9915771.
      View in: PubMed   Mentions:
    2. Structural variation across 138,134 samples in the TOPMed consortium. bioRxiv. 2023 Jan 25. Jun G, English AC, Metcalf GA, Yang J, Chaisson MJ, Pankratz N, Menon VK, Salerno WJ, Krasheninina O, Smith AV, Lane JA, Blackwell T, Kang HM, Salvi S, Meng Q, Shen H, Pasham D, Bhamidipati S, Kottapalli K, Arnett DK, Ashley-Koch A, Auer PL, Beutel KM, Bis JC, Blangero J, Bowden DW, Brody JA, Cade BE, Chen YI, Cho MH, Curran JE, Fornage M, Freedman BI, Fingerlin T, Gelb BD, Hou L, Hung YJ, Kane JP, Kaplan R, Kim W, Loos RJF, Marcus GM, Mathias RA, McGarvey ST, Montgomery C, Naseri T, Nouraie SM, Preuss MH, Palmer ND, Peyser PA, Raffield LM, Ratan A, Redline S, Reupena S, Rotter JI, Rich SS, Rienstra M, Ruczinski I, Sankaran VG, Schwartz DA, Seidman CE, Seidman JG, Silverman EK, Smith JA, Stilp A, Taylor KD, Telen MJ, Weiss ST, Williams LK, Wu B, Yanek LR, Zhang Y, Lasky-Su J, Gingras MC, Dutcher SK, Eichler EE, Gabriel S, Germer S, Kim R, Viaud-Martinez KA, Nickerson DA, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Luo J, Reiner A, Gibbs RA, Boerwinkle E, Abecasis G, Sedlazeck FJ. PMID: 36747810; PMCID: PMC9900832.
      View in: PubMed   Mentions:
    3. Elastin Degradation and Lung Function Deterioration with Remote Secondhand Tobacco Smoke Exposure in Never-smokers. Chronic Obstr Pulm Dis. 2022 Jul 29; 9(3):377-393. Mustra Rakic J, Zeng S, Rohdin-Bibby L, Van Blarigan EL, Liu X, Ma S, Kane JP, Redberg RF, Turino GM, Oestreicher Stock E, Arjomandi M. PMID: 35700534; PMCID: PMC9448014.
      View in: PubMed   Mentions:
    4. Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia. J Lipid Res. 2022 06; 63(6):100209. Dong W, Wong KHY, Liu Y, Levy-Sakin M, Hung WC, Li M, Li B, Jin SC, Choi J, Lopez-Giraldez F, Vaka D, Poon A, Chu C, Lao R, Balamir M, Movsesyan I, Malloy MJ, Zhao H, Kwok PY, Kane JP, Lifton RP, Pullinger CR. PMID: 35460704; PMCID: PMC9126845.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus. Curr Opin Pharmacol. 2021 12; 61:21-27. Kane JP, Pullinger CR, Goldfine ID, Malloy MJ. PMID: 34562838.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    6. Machine learning and statistical approaches for classification of risk of coronary artery disease using plasma cytokines. BioData Min. 2021 Apr 15; 14(1):26. Saharan SS, Nagar P, Creasy KT, Stock EO, Feng J, Malloy MJ, Kane JP. PMID: 33858484; PMCID: PMC8050889.
      View in: PubMed   Mentions: 1  
    7. Levels of Prebeta-1 High-Density Lipoprotein Are a Strong Independent Positive Risk Factor for Coronary Heart Disease and Myocardial Infarction: A Meta-Analysis. J Am Heart Assoc. 2021 04 06; 10(7):e018381. Pullinger CR, O'Connor PM, Naya-Vigne JM, Kunitake ST, Movsesyan I, Frost PH, Malloy MJ, Kane JP. PMID: 33728928; PMCID: PMC8174380.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Ancestry-specific profiles of genetic determinants of severe hypertriglyceridemia. J Clin Lipidol. 2021 Jan-Feb; 15(1):88-96. Gill PK, Dron JS, Dilliott AA, McIntyre AD, Cao H, Wang J, Movsesyan IG, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. PMID: 33303403.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2020 08; 40(8):1935-1941. Dron JS, Dilliott AA, Lawson A, McIntyre AD, Davis BD, Wang J, Cao H, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. PMID: 32580631.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    10. Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method. J Lipid Res. 2020 03; 61(3):455-463. Jones GM, Caccavello R, Palii SP, Pullinger CR, Kane JP, Mulligan K, Gugliucci A, Schwarz JM. PMID: 31888979; PMCID: PMC7053834.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Three patients with homozygous familial hypercholesterolemia: Genomic sequencing and kindred analysis. Mol Genet Genomic Med. 2019 12; 7(12):e1007. Wong KHY, Levy-Sakin M, Ma W, Gonzaludo N, Mak ACY, Vaka D, Poon A, Chu C, Lao R, Balamir M, Grenville Z, Wong N, Kane JP, Kwok PY, Malloy MJ, Pullinger CR. PMID: 31617323; PMCID: PMC6900368.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    12. Cardiac 123I-MIBG normal uptake values are population-specific: Results from a cohort of controls over 60 years of age. J Nucl Cardiol. 2021 08; 28(4):1692-1701. Roberts G, Lloyd JJ, Kane JPM, Durcan R, Lawley S, Howe K, Petrides GS, O'Brien JT, Thomas AJ. PMID: 31529384.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Partial LPL deletions: rare copy-number variants contributing towards severe hypertriglyceridemia. J Lipid Res. 2019 11; 60(11):1953-1958. Dron JS, Wang J, McIntyre AD, Cao H, Robinson JF, Duell PB, Manjoo P, Feng J, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. PMID: 31519763; PMCID: PMC6824486.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Emerging roles of HDL in immune function. Curr Opin Lipidol. 2018 12; 29(6):486-487. Creasy KT, Kane JP, Malloy MJ. PMID: 30382953.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Severe hypertriglyceridemia is primarily polygenic. J Clin Lipidol. 2019 Jan - Feb; 13(1):80-88. Dron JS, Wang J, Cao H, McIntyre AD, Iacocca MA, Menard JR, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. PMID: 30466821.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    16. Multi-ethnic genome-wide association study for atrial fibrillation. Nat Genet. 2018 06 11; 50(9):1225-1233. Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, D?rr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, K??b S, K?h?nen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtim?ki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytik?inen LP, Macfarlane PW, Magnusson PK, Mahajan A, Malik R, Mansur AJ, Marcus GM, Margolin L, Margulies KB, M?rz W, McManus DD, Melander O, Mohanty S, Montgomery JA, Morley MP, Morris AP, M?ller-Nurasyid M, Natale A, Nazarian S, Neumann B, Newton-Cheh C, Niemeijer MN, Nikus K, Nilsson P, Noordam R, Oellers H, Olesen MS, Orho-Melander M, Padmanabhan S, Pak HN, Par? G, Pedersen NL, Pera J, Pereira A, Porteous D, Psaty BM, Pulit SL, Pullinger CR, Rader DJ, Refsgaard L, Ribas?s M, Ridker PM, Rienstra M, Risch L, Roden DM, Rosand J, Rosenberg MA, Rost N, Rotter JI, Saba S, Sandhu RK, Schnabel RB, Schramm K, Schunkert H, Schurman C, Scott SA, Sepp?l? I, Shaffer C, Shah S, Shalaby AA, Shim J, Shoemaker MB, Siland JE, Sinisalo J, Sinner MF, Slowik A, Smith AV, Smith BH, Smith JG, Smith JD, Smith NL, Soliman EZ, Sotoodehnia N, Stricker BH, Sun A, Sun H, Svendsen JH, Tanaka T, Tanriverdi K, Taylor KD, Teder-Laving M, Teumer A, Th?riault S, Trompet S, Tucker NR, Tveit A, Uitterlinden AG, Van Der Harst P, Van Gelder IC, Van Wagoner DR, Verweij N, Vlachopoulou E, V?lker U, Wang B, Weeke PE, Weijs B, Weiss R, Weiss S, Wells QS, Wiggins KL, Wong JA, Woo D, Worrall BB, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Lubitz SA, Lunetta KL, Ellinor PT. PMID: 29892015; PMCID: PMC6136836.
      View in: PubMed   Mentions: 244     Fields:    Translation:HumansCells
    17. Levels of prebeta-1 high-density lipoprotein are elevated in 3 phenotypes of dyslipidemia. J Clin Lipidol. 2018 Jan - Feb; 12(1):99-109. Stock EO, Ferrara CT, O'Connor PM, Naya-Vigne JM, Frost PH, Malloy MJ, Kane JP, Pullinger CR. PMID: 29198898.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    18. Moderate statin treatment reduces prebeta-1 high-density lipoprotein levels in dyslipidemic patients. J Clin Lipidol. 2017 Jul - Aug; 11(4):908-914. Quinn AG, Schwemberger R, Stock EO, Movsesyan I, Axtell A, Chang S, Ishida BY, Malloy MJ, Kane JP, Pullinger CR. PMID: 28558949.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Biochemical Analysis of the Lipoprotein Lipase Truncation Variant, LPLS447X, Reveals Increased Lipoprotein Uptake. Biochemistry. 2017 01 24; 56(3):525-533. Hayne CK, Lafferty MJ, Eglinger BJ, Kane JP, Neher SB. PMID: 27984852; PMCID: PMC5848218.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    20. Lipoproteins and amyloid vascular disease. Curr Opin Lipidol. 2016 12; 27(6):640-641. Kane JP, Malloy MJ. PMID: 27805977.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Familial hypercholesterolaemia: cholesterol efflux and coronary disease. Eur J Clin Invest. 2016 Jul; 46(7):643-50. Versmissen J, Vongpromek R, Yahya R, van der Net JB, van Vark-van der Zee L, Blommesteijn-Touw J, Wattimena D, Rietveld T, Pullinger CR, Christoffersen C, Dahlb?ck B, Kane JP, Mulder M, Sijbrands EJ. PMID: 27208892; PMCID: PMC5113689.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    22. Infectious basophilia? Am J Hematol. 2016 Feb; 91(2):E8. Kane JP. PMID: 26572775.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    23. Emerging molecular strategies for management of dyslipidemias. Curr Opin Lipidol. 2015 Dec; 26(6):601-2. Kane JP, Malloy MJ. PMID: 26780015.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib. J Am Coll Cardiol. 2015 Nov 17; 66(20):2201-2210. Nicholls SJ, Ruotolo G, Brewer HB, Kane JP, Wang MD, Krueger KA, Adelman SJ, Nissen SE, Rader DJ. PMID: 26564598.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCTClinical Trials
    25. An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish. Elife. 2015 Oct 16; 4:e09406. Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC. PMID: 26473617; PMCID: PMC4720518.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    26. Identification and metabolic profiling of patients with lysosomal acid lipase deficiency. J Clin Lipidol. 2015 Sep-Oct; 9(5):716-26.e1. Pullinger CR, Stock EO, Movsesyan I, Malloy MJ, Frost PH, Tripuraneni R, Quinn AG, Ishida BY, Schaefer EJ, Asztalos BF, Kane JP. PMID: 26350820.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    27. HDL cholesterol efflux capacity and cardiovascular events. N Engl J Med. 2015 05 07; 372(19):1871. Kane JP, Malloy MJ, Pullinger CR. PMID: 25946301.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Exome sequencing in suspected monogenic dyslipidemias. Circ Cardiovasc Genet. 2015 Apr; 8(2):343-50. Stitziel NO, Peloso GM, Abifadel M, Cefalu AB, Fouchier S, Motazacker MM, Tada H, Larach DB, Awan Z, Haller JF, Pullinger CR, Varret M, Rab?s JP, Noto D, Tarugi P, Kawashiri MA, Nohara A, Yamagishi M, Risman M, Deo R, Ruel I, Shendure J, Nickerson DA, Wilson JG, Rich SS, Gupta N, Farlow DN, Neale BM, Daly MJ, Kane JP, Freeman MW, Genest J, Rader DJ, Mabuchi H, Kastelein JJ, Hovingh GK, Averna MR, Gabriel S, Boileau C, Kathiresan S. PMID: 25632026; PMCID: PMC4406825.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    29. Congenital absence of apolipoprotein E and neurological function-reply. JAMA Neurol. 2014 Dec; 71(12):1579. Malloy MJ, Kane JP. PMID: 25486213.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. JAMA Neurol. 2014 Oct; 71(10):1228-36. Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, Castellano JM, Wyss-Coray T, Duncan JL, Miller BL, Kane JP, Kwok PY, Malloy MJ. PMID: 25111166; PMCID: PMC4714860.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    31. Aberrant hetero-disulfide bond formation by the hypertriglyceridemia-associated p.Gly185Cys APOA5 variant (rs2075291). Arterioscler Thromb Vasc Biol. 2014 Oct; 34(10):2254-60. Sharma V, Witkowski A, Witkowska HE, Dykstra A, Simonsen JB, Nelbach L, Beckstead JA, Pullinger CR, Kane JP, Malloy MJ, Watson G, Forte TM, Ryan RO. PMID: 25127531; PMCID: PMC4178935.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    32. Sebelipase alfa over 52 weeks reduces serum transaminases, liver volume and improves serum lipids in patients with lysosomal acid lipase deficiency. J Hepatol. 2014 Nov; 61(5):1135-42. Valayannopoulos V, Malinova V, Honz?k T, Balwani M, Breen C, Deegan PB, Enns GM, Jones SA, Kane JP, Stock EO, Tripuraneni R, Eckert S, Schneider E, Hamilton G, Middleton MS, Sirlin C, Kessler B, Bourdon C, Boyadjiev SA, Sharma R, Twelves C, Whitley CB, Quinn AG. PMID: 24993530; PMCID: PMC4203712.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    33. Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients. Diabetes Metab. 2014 Dec; 40(6):452-8. Arndt C, Leclercq I, Nazeyrollas P, Durlach A, Ducasse A, Movesayan I, Socquard E, Clavel C, Malloy MM, Pullinger CR, Kane JP, Durlach V. PMID: 24852509.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Lipoprotein (a), LPA Ile4399Met, and fibrin clot properties. Thromb Res. 2014 May; 133(5):863-7. Rowland CM, Pullinger CR, Luke MM, Shiffman D, Green L, Movsesyan I, Devlin JJ, Malloy MJ, Kane JP, Undas A. PMID: 24502962.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    35. Impact of a 4q25 genetic variant in atrial flutter and on the risk of atrial fibrillation after cavotricuspid isthmus ablation. J Cardiovasc Electrophysiol. 2014 Mar; 25(3):271-277. Roberts JD, Hsu JC, Aouizerat BE, Pullinger CR, Malloy MJ, Kane JP, Olgin JE, Marcus GM. PMID: 24237655; PMCID: PMC3947706.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    36. Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population. Metab Syndr Relat Disord. 2014 Feb; 12(1):25-30. Pullinger CR, Goldfine ID, Tanyola? S, Movsesyan I, Faynboym M, Durlach V, Chiefari E, Foti DP, Frost PH, Malloy MJ, Brunetti A, Kane JP. PMID: 24148075.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    37. Needed: a better understanding of the antiatherogenic properties of HDL. Curr Opin Lipidol. 2013 Oct; 24(5):453-4. Kane JP, Malloy MJ. PMID: 24005220.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    38. New horizons in lipid management. J Am Coll Cardiol. 2013 Sep 24; 62(13):1163-4. Kane JP. PMID: 23770169.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Deficiency of TDAG51 protects against atherosclerosis by modulating apoptosis, cholesterol efflux, and peroxiredoxin-1 expression. J Am Heart Assoc. 2013 May 17; 2(3):e000134. Hossain GS, Lynn EG, Maclean KN, Zhou J, Dickhout JG, Lhot?k S, Trigatti B, Capone J, Rho J, Tang D, McCulloch CA, Al-Bondokji I, Malloy MJ, Pullinger CR, Kane JP, Li Y, Shiffman D, Austin RC. PMID: 23686369; PMCID: PMC3698773.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    40. Clinical effect and safety profile of recombinant human lysosomal acid lipase in patients with cholesteryl ester storage disease. Hepatology. 2013 Sep; 58(3):950-7. Balwani M, Breen C, Enns GM, Deegan PB, Honz?k T, Jones S, Kane JP, Malinova V, Sharma R, Stock EO, Valayannopoulos V, Wraith JE, Burg J, Eckert S, Schneider E, Quinn AG. PMID: 23348766; PMCID: PMC3728169.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCTClinical Trials
    41. Hyperlipidemia and cardiovascular disease. Curr Opin Lipidol. 2012 Dec; 23(6):591-2. Malloy MJ, Kane JP. PMID: 23160407.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    42. Prebeta-1 HDL and coronary heart disease. Curr Opin Lipidol. 2012 Aug; 23(4):367-71. Kane JP, Malloy MJ. PMID: 22517613.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    43. New molecular insights into CETP structure and function: a review. J Lipid Res. 2012 Aug; 53(8):1451-8. Charles MA, Kane JP. PMID: 22679067; PMCID: PMC3540851.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    44. Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis. Am J Hum Genet. 2012 May 04; 90(5):796-808. Jordan CT, Cao L, Roberson ED, Duan S, Helms CA, Nair RP, Duffin KC, Stuart PE, Goldgar D, Hayashi G, Olfson EH, Feng BJ, Pullinger CR, Kane JP, Wise CA, Goldbach-Mansky R, Lowes MA, Peddle L, Chandran V, Liao W, Rahman P, Krueger GG, Gladman D, Elder JT, Menter A, Bowcock AM. PMID: 22521419; PMCID: PMC3376540.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansCells
    45. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2012 Jun; 9(6):961-7. Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM. PMID: 22300662; PMCID: PMC3349006.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    46. Polymorphisms and noncardioembolic stroke in three case-control studies. Cerebrovasc Dis. 2012; 33(1):80-5. Luke MM, Berger K, Rowland CM, Catanese JJ, Tong CH, Ross DA, Garcia V, Kuhlenbaeumer G, Ringelstein EB, Pullinger CR, Malloy MJ, Deedwania P, Ellis SG, Kane JP, Devlin JJ, Lalouschek W, Mannhalter C. PMID: 22134093.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. Association between regulator of G protein signaling 9-2 and body weight. PLoS One. 2011; 6(11):e27984. Waugh JL, Celver J, Sharma M, Dufresne RL, Terzi D, Risch SC, Fairbrother WG, Neve RL, Kane JP, Malloy MJ, Pullinger CR, Gu HF, Tsatsanis C, Hamilton SP, Gold SJ, Zachariou V, Kovoor A. PMID: 22132185; PMCID: PMC3223194.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    48. Relation of increased prebeta-1 high-density lipoprotein levels to risk of coronary heart disease. Am J Cardiol. 2011 Aug 01; 108(3):360-6. Guey LT, Pullinger CR, Ishida BY, O'Connor PM, Zellner C, Francone OL, Laramie JM, Naya-Vigne JM, Siradze KA, Deedwania P, Redberg RF, Frost PH, Seymour AB, Kane JP, Malloy MJ. PMID: 21757044.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    49. Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2012 Jul 15; 59(1):52-6. DuBois SG, Goldsby R, Segal M, Woo J, Copren K, Kane JP, Pullinger CR, Matthay KK, Witte J, Lessnick SL, Robison LL, Bhatia S, Strong LC. PMID: 21793187; PMCID: PMC3204324.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    50. Mechanisms of statin-induced myalgia assessed by physiogenomic associations. Atherosclerosis. 2011 Oct; 218(2):451-6. Rua?o G, Windemuth A, Wu AH, Kane JP, Malloy MJ, Pullinger CR, Kocherla M, Bogaard K, Gordon BR, Holford TR, Gupta A, Seip RL, Thompson PD. PMID: 21868014; PMCID: PMC3224998.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    51. Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels. J Lipid Res. 2011 Nov; 52(11):1974-83. Francone OL, Ishida BY, de la Llera-Moya M, Royer L, Happe C, Zhu J, Chalkey RJ, Schaefer P, Cox C, Burlingame A, Kane JP, Rothblat GH. PMID: 21771977; PMCID: PMC3196229.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    52. Functional variants of the HMGA1 gene and type 2 diabetes mellitus. JAMA. 2011 Mar 02; 305(9):903-12. Chiefari E, Tanyola? S, Paonessa F, Pullinger CR, Capula C, Iiritano S, Mazza T, Forlin M, Fusco A, Durlach V, Durlach A, Malloy MJ, Kane JP, Heiner SW, Filocamo M, Foti DP, Goldfine ID, Brunetti A. PMID: 21364139.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    53. Association of endothelial lipase Thr111Ile polymorphism with lipid metabolism and microvascular complications in type 2 diabetic patients. Diabetes Metab. 2011 Feb; 37(1):64-71. Durlach V, Durlach A, Movesayan I, Socquard E, Zellner C, Clavel C, Nazeyrollas P, Malloy MJ, Pullinger CR, Kane JP, Ducasse A, Aouizerat BE. PMID: 21145773.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy. J Lipid Res. 2011 Jan; 52(1):175-84. Zhang L, Song J, Cavigiolio G, Ishida BY, Zhang S, Kane JP, Weisgraber KH, Oda MN, Rye KA, Pownall HJ, Ren G. PMID: 20978167; PMCID: PMC2999936.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    55. Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Pharmacogenomics. 2010 Jul; 11(7):959-71. Rua?o G, Thompson PD, Kane JP, Pullinger CR, Windemuth A, Seip RL, Kocherla M, Holford TR, Wu AH. PMID: 20602615; PMCID: PMC2921920.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    56. Metabolic abnormalities and coronary heart disease risk in human immunodeficiency virus-infected adults. Metab Syndr Relat Disord. 2010 Jun; 8(3):279-86. Pullinger CR, Aouizerat BE, Gay C, Coggins T, Movsesyan I, Davis H, Kane JP, Portillo C, Lee KA. PMID: 20235745; PMCID: PMC3085320.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    57. Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus. Atherosclerosis. 2010 Sep; 212(1):193-6. Shiffman D, Louie JZ, Rowland CM, Malloy MJ, Kane JP, Devlin JJ. PMID: 20605575.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    58. Effect of niacin on preβ-1 high-density lipoprotein levels in diabetes. Metabolism. 2011 Feb; 60(2):292-7. Pan J, Shilian P, Ishida B, Wu X, Kane JP, Malloy MJ, Charles MA. PMID: 20303127.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    59. High-density lipoprotein metabolism and the human embryo. Hum Reprod Update. 2010 Jan-Feb; 16(1):20-38. Fujimoto VY, Kane JP, Ishida BY, Bloom MS, Browne RW. PMID: 19700490.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    60. Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects. Metab Syndr Relat Disord. 2009 Dec; 7(6):543-8. Tanyolaç S, Bremer AA, Hodoglugil U, Movsesyan I, Pullinger CR, Heiner SW, Malloy MJ, Kane JP, Goldfine ID. PMID: 19656007; PMCID: PMC3139525.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    61. The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles. Atherosclerosis. 2010 Apr; 209(2):498-503. Arai K, Luke MM, Koschinsky ML, Miller ER, Pullinger CR, Witztum JL, Kane JP, Tsimikas S. PMID: 19880117.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    62. HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property. FASEB J. 2009 Sep; 23(9):3129-39. Ortiz-Muñoz G, Houard X, Martín-Ventura JL, Ishida BY, Loyau S, Rossignol P, Moreno JA, Kane JP, Chalkley RJ, Burlingame AL, Michel JB, Meilhac O. PMID: 19417089; PMCID: PMC2735359.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    63. Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium. Br J Ophthalmol. 2009 Aug; 93(8):1116-20. Duncan KG, Hosseini K, Bailey KR, Yang H, Lowe RJ, Matthes MT, Kane JP, LaVail MM, Schwartz DM, Duncan JL. PMID: 19304587; PMCID: PMC3541028.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    64. Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1. J Lipid Res. 2009 Jul; 50(7):1330-9. Zhu J, Gardner J, Pullinger CR, Kane JP, Thompson JF, Francone OL. PMID: 19237735; PMCID: PMC2694332.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    65. Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Hum Mol Genet. 2009 Mar 15; 18(6):1140-7. Calton MA, Ersoy BA, Zhang S, Kane JP, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R, Ahituv N, Vaisse C. PMID: 19091795; PMCID: PMC2649015.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    66. GOSR2 Lys67Arg is associated with hypertension in whites. Am J Hypertens. 2009 Feb; 22(2):163-8. Meyer TE, Shiffman D, Morrison AC, Rowland CM, Louie JZ, Bare LA, Ross DA, Arellano AR, Chasman DI, Ridker PM, Pankow JS, Coresh J, Malloy MJ, Kane JP, Ellis SG, Devlin JJ, Boerwinkle E. PMID: 19057520; PMCID: PMC4346180.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    67. Galanin preproprotein is associated with elevated plasma triglycerides. Arterioscler Thromb Vasc Biol. 2009 Jan; 29(1):147-52. Plaisier CL, Kyttälä M, Weissglas-Volkov D, Sinsheimer JS, Huertas-Vazquez A, Riba L, Ramírez-Jiménez S, de Bruin TW, Tusié-Luna T, Aouizerat BE, Pullinger CR, Malloy MJ, Kane JP, Cruz-Bautista I, Herrera MF, Aguilar-Salinas C, Kuusisto J, Laakso M, Taskinen MR, van der Kallen CJ, Pajukanta P. PMID: 18988886; PMCID: PMC2650822.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    68. Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction. PLoS One. 2008 Aug 06; 3(8):e2895. Shiffman D, Kane JP, Louie JZ, Arellano AR, Ross DA, Catanese JJ, Malloy MJ, Ellis SG, Devlin JJ. PMID: 18682748; PMCID: PMC2483345.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    69. Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and coronary heart disease risk in familial hypercholesterolemia. Atherosclerosis. 2009 Apr; 203(2):472-8. van der Net JB, Versmissen J, Oosterveer DM, Defesche JC, Yazdanpanah M, Aouizerat BE, Steyerberg EW, Malloy MJ, Pullinger CR, Kane JP, Kastelein JJ, Sijbrands EJ. PMID: 18775537.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    70. WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels. Am J Hum Genet. 2008 Aug; 83(2):180-92. Lee JC, Weissglas-Volkov D, Kyttälä M, Dastani Z, Cantor RM, Sobel EM, Plaisier CL, Engert JC, van Greevenbroek MM, Kane JP, Malloy MJ, Pullinger CR, Huertas-Vazquez A, Aguilar-Salinas CA, Tusie-Luna T, de Bruin TW, Aouizerat BE, van der Kallen CC, Croce CM, Aqeilan RI, Marcil M, Viikari JS, Lehtimäki T, Raitakari OT, Kuusisto J, Laakso M, Taskinen MR, Genest J, Pajukanta P. PMID: 18674750; PMCID: PMC2495060.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    71. Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. Eur Heart J. 2008 Sep; 29(18):2195-201. van der Net JB, Oosterveer DM, Versmissen J, Defesche JC, Yazdanpanah M, Aouizerat BE, Steyerberg EW, Malloy MJ, Pullinger CR, Kastelein JJ, Kane JP, Sijbrands EJ. PMID: 18599554; PMCID: PMC2733738.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    72. An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients. J Lipid Res. 2008 Aug; 49(8):1846-54. Pullinger CR, Aouizerat BE, Movsesyan I, Durlach V, Sijbrands EJ, Nakajima K, Poon A, Dallinga-Thie GM, Hattori H, Green LL, Kwok PY, Havel RJ, Frost PH, Malloy MJ, Kane JP. PMID: 18441017; PMCID: PMC2444008.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    73. A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet. 2008 Mar 28; 4(3):e1000041. Liu Y, Helms C, Liao W, Zaba LC, Duan S, Gardner J, Wise C, Miner A, Malloy MJ, Pullinger CR, Kane JP, Saccone S, Worthington J, Bruce I, Kwok PY, Menter A, Krueger J, Barton A, Saccone NL, Bowcock AM. PMID: 18369459; PMCID: PMC2274885.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansCells
    74. Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat Genet. 2007 Dec; 39(12):1483-7. Péterfy M, Ben-Zeev O, Mao HZ, Weissglas-Volkov D, Aouizerat BE, Pullinger CR, Frost PH, Kane JP, Malloy MJ, Reue K, Pajukanta P, Doolittle MH. PMID: 17994020.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    75. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 2008 Jan; 28(1):173-9. Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP, Ellis SG, Tracy RP, Devlin JJ, Psaty BM. PMID: 17975119; PMCID: PMC2636623.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    76. Five common gene variants identify elevated genetic risk for coronary heart disease. Genet Med. 2007 Oct; 9(10):682-9. Bare LA, Morrison AC, Rowland CM, Shiffman D, Luke MM, Iakoubova OA, Kane JP, Malloy MJ, Ellis SG, Pankow JS, Willerson JT, Devlin JJ, Boerwinkle E. PMID: 18073581.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    77. Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery. Anesthesiology. 2007 Sep; 107(3):406-11. Leung JM, Sands LP, Wang Y, Poon A, Kwok PY, Kane JP, Pullinger CR. PMID: 17721242.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    78. Assessment of lipoprotein profiles study (ALPS) and antioxidant activity in healthy subjects treated with AGI-1067. J Clin Lipidol. 2007 Aug; 1(4):271-9. Davidson MH, Smith J, Scott R, Small R, Choi J, Ishida BY, Kane JP, ALPS Investigators. PMID: 21291691.
      View in: PubMed   Mentions: 1     Fields:    
    79. A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease. Arterioscler Thromb Vasc Biol. 2007 Sep; 27(9):2030-6. Luke MM, Kane JP, Liu DM, Rowland CM, Shiffman D, Cassano J, Catanese JJ, Pullinger CR, Leong DU, Arellano AR, Tong CH, Movsesyan I, Naya-Vigne J, Noordhof C, Feric NT, Malloy MJ, Topol EJ, Koschinsky ML, Devlin JJ, Ellis SG. PMID: 17569884.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    80. Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. Am J Epidemiol. 2007 Jul 01; 166(1):28-35. Morrison AC, Bare LA, Chambless LE, Ellis SG, Malloy M, Kane JP, Pankow JS, Devlin JJ, Willerson JT, Boerwinkle E. PMID: 17443022.
      View in: PubMed   Mentions: 134     Fields:    Translation:Humans
    81. The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion. Lipids Health Dis. 2006 Jul 05; 5:19. Wung SF, Kulkarni MV, Pullinger CR, Malloy MJ, Kane JP, Aouizerat BE. PMID: 16822320; PMCID: PMC1538992.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    82. Gene variants of VAMP8 and HNRPUL1 are associated with early-onset myocardial infarction. Arterioscler Thromb Vasc Biol. 2006 Jul; 26(7):1613-8. Shiffman D, Rowland CM, Louie JZ, Luke MM, Bare LA, Bolonick JI, Young BA, Catanese JJ, Stiggins CF, Pullinger CR, Topol EJ, Malloy MJ, Kane JP, Ellis SG, Devlin JJ. PMID: 16690874.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    83. High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture. Br J Ophthalmol. 2006 May; 90(5):616-20. Ishida BY, Duncan KG, Bailey KR, Kane JP, Schwartz DM. PMID: 16622093; PMCID: PMC1857047.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    84. Lack of support for the association between GAD2 polymorphisms and severe human obesity. PLoS Biol. 2005 Sep; 3(9):e315. Swarbrick MM, Waldenmaier B, Pennacchio LA, Lind DL, Cavazos MM, Geller F, Merriman R, Ustaszewska A, Malloy M, Scherag A, Hsueh WC, Rief W, Mauvais-Jarvis F, Pullinger CR, Kane JP, Dent R, McPherson R, Kwok PY, Hinney A, Hebebrand J, Vaisse C. PMID: 16122350; PMCID: PMC1193520.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    85. Identification of four gene variants associated with myocardial infarction. Am J Hum Genet. 2005 Oct; 77(4):596-605. Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane JP. PMID: 16175505; PMCID: PMC1275608.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    86. Parotid secretory protein is an HDL-associated protein with anticandidal activity. Am J Physiol Regul Integr Comp Physiol. 2005 May; 288(5):R1306-15. Khovidhunkit W, Hachem JP, Medzihradszky KF, Duchateau PN, Shigenaga JK, Moser AH, Movsesyan I, Naya-Vigne J, Kane JP, Feingold KR, Grunfeld C. PMID: 15637169.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    87. Variations in human HM74 (GPR109B) and HM74A (GPR109A) niacin receptors. Hum Mutat. 2005 Jan; 25(1):18-21. Zellner C, Pullinger CR, Aouizerat BE, Frost PH, Kwok PY, Malloy MJ, Kane JP. PMID: 15580557.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    88. Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL. J Lipid Res. 2005 Mar; 46(3):469-74. Albert TS, Duchateau PN, Deeb SS, Pullinger CR, Cho MH, Heilbron DC, Malloy MJ, Kane JP, Brown BG. PMID: 15604524.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    89. Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL. Atherosclerosis. 2004 Sep; 176(1):37-44. Khovidhunkit W, Duchateau PN, Medzihradszky KF, Moser AH, Naya-Vigne J, Shigenaga JK, Kane JP, Grunfeld C, Feingold KR. PMID: 15306172.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    90. The primary stone event: a new hypothesis involving a vascular etiology. J Urol. 2004 May; 171(5):1920-4. Stoller ML, Meng MV, Abrahams HM, Kane JP. PMID: 15076312.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    91. Regulated expression of apolipoprotein E by human retinal pigment epithelial cells. J Lipid Res. 2004 Feb; 45(2):263-71. Ishida BY, Bailey KR, Duncan KG, Chalkley RJ, Burlingame AL, Kane JP, Schwartz DM. PMID: 14594998.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    92. Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts. Biochem Biophys Res Commun. 2003 Jun 27; 306(2):463-8. Huuskonen J, Abedin M, Vishnu M, Pullinger CR, Baranzini SE, Kane JP, Fielding PE, Fielding CJ. PMID: 12804586.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    93. Apolipoprotein A-II: active or passive role in familial combined hyperlipidemia. Circ Res. 2003 Jun 13; 92(11):1179-81. Aouizerat BE, Kane JP. PMID: 12805235.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    94. Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders. Expert Rev Cardiovasc Ther. 2003 May; 1(1):107-19. Pullinger CR, Kane JP, Malloy MJ. PMID: 15030301.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    95. Genetic analysis of a polymorphism in the human apoA-V gene: effect on plasma lipids. J Lipid Res. 2003 Jun; 44(6):1167-73. Aouizerat BE, Kulkarni M, Heilbron D, Drown D, Raskin S, Pullinger CR, Malloy MJ, Kane JP. PMID: 12671030.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    96. The effects of physical exercise on plasma prebeta-1 high-density lipoprotein. Metabolism. 2003 Apr; 52(4):437-42. Jafari M, Leaf DA, Macrae H, Kasem J, O'conner P, Pullinger C, Malloy M, Kane JP. PMID: 12701055.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    97. Apolipoprotein L-I is the trypanosome lytic factor of human serum. Nature. 2003 Mar 06; 422(6927):83-7. Vanhamme L, Paturiaux-Hanocq F, Poelvoorde P, Nolan DP, Lins L, Van Den Abbeele J, Pays A, Tebabi P, Van Xong H, Jacquet A, Moguilevsky N, Dieu M, Kane JP, De Baetselier P, Brasseur R, Pays E. PMID: 12621437.
      View in: PubMed   Mentions: 209     Fields:    Translation:HumansAnimalsCells
    98. Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. J Clin Invest. 2002 Jul; 110(1):109-17. Pullinger CR, Eng C, Salen G, Shefer S, Batta AK, Erickson SK, Verhagen A, Rivera CR, Mulvihill SJ, Malloy MJ, Kane JP. PMID: 12093894; PMCID: PMC151029.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansCells
    99. Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding. Clin Chim Acta. 2002 Jul; 321(1-2):113-21. Gaffney D, Pullinger CR, O'Reilly DS, Hoffs MS, Cameron I, Vass JK, Kulkarni MV, Kane JP, Schumaker VN, Watts GF, Packard CJ. PMID: 12031600.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    100. Human retinal pigment epithelial cells express scavenger receptors BI and BII. Biochem Biophys Res Commun. 2002 Apr 12; 292(4):1017-22. Duncan KG, Bailey KR, Kane JP, Schwartz DM. PMID: 11944916.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    101. Does hypertriglyceridemia present an indication for pioglitazone therapy in diabetes? Diabetes Technol Ther. 2002; 4(2):153-5. Kane JP. PMID: 12079618.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    102. Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. J Lipid Res. 2001 Apr; 42(4):620-30. Duchateau PN, Pullinger CR, Cho MH, Eng C, Kane JP. PMID: 11290834.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    103. Elevated baseline triglyceride levels modulate effects of HMGCoA reductase inhibitors on plasma lipoproteins. J Cardiovasc Pharmacol Ther. 2001 Jan; 6(1):47-56. Drmanac S, Heilbron DC, Pullinger CR, Jafari M, Gietzen D, Ukrainczyk T, Cho MH, Frost PH, Siradze K, Drmanac RT, Kane JP, Malloy MJ. PMID: 11452336.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    104. Haplotypes of the human renin gene associated with essential hypertension and stroke. J Hum Hypertens. 2001 Jan; 15(1):49-55. Frossard PM, Malloy MJ, Lestringant GG, Kane JP. PMID: 11224002.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    105. A risk factor for atherosclerosis: triglyceride-rich lipoproteins. Adv Intern Med. 2001; 47:111-36. Malloy MJ, Kane JP. PMID: 11795072.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    106. Plasma apolipoprotein L concentrations correlate with plasma triglycerides and cholesterol levels in normolipidemic, hyperlipidemic, and diabetic subjects. J Lipid Res. 2000 Aug; 41(8):1231-6. Duchateau PN, Movsesyan I, Yamashita S, Sakai N, Hirano K, Schoenhaus SA, O'Connor-Kearns PM, Spencer SJ, Jaffe RB, Redberg RF, Ishida BY, Matsuzawa Y, Kane JP, Malloy MJ. PMID: 10946010.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    107. Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype. J Lipid Res. 2000 Aug; 41(8):1290-301. Mahley RW, Pépin J, Palaoglu KE, Malloy MJ, Kane JP, Bersot TP. PMID: 10946017.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    108. Analysis of hABC1 gene 5' end: additional peptide sequence, promoter region, and four polymorphisms. Biochem Biophys Res Commun. 2000 May 10; 271(2):451-5. Pullinger CR, Hakamata H, Duchateau PN, Eng C, Aouizerat BE, Cho MH, Fielding CJ, Kane JP. PMID: 10799318.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    109. Lack of association of lipoprotein(a) levels with coronary calcium deposits in asymptomatic postmenopausal women. J Am Coll Cardiol. 2000 Feb; 35(2):314-20. Nishino M, Malloy MJ, Naya-Vigne J, Russell J, Kane JP, Redberg RF. PMID: 10676675.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    110. Human renin gene BglI dimorphism associated with hypertension in two independent populations. Clin Genet. 1999 Dec; 56(6):428-33. Frossard PM, Lestringant GG, Malloy MJ, Kane JP. PMID: 10665661.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    111. Renin gene MboI dimorphism is a discriminator for hypertension in hyperlipidaemic subjects. Hypertens Res. 1999 Nov; 22(4):285-9. Frossard PM, Kane JP, Malloy MJ, Bener A. PMID: 10580395.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    112. Evaluation of Langerhans' cells in the cervical epithelium of women with cervical intraepithelial neoplasia. Gynecol Oncol. 1999 Oct; 75(1):130-5. Connor JP, Ferrer K, Kane JP, Goldberg JM. PMID: 10502439.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    113. A multilocus genotyping assay for candidate markers of cardiovascular disease risk. Genome Res. 1999 Oct; 9(10):936-49. Cheng S, Grow MA, Pallaud C, Klitz W, Erlich HA, Visvikis S, Chen JJ, Pullinger CR, Malloy MJ, Siest G, Kane JP. PMID: 10523522; PMCID: PMC310821.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    114. Polymorphism of the lipopolysaccharide receptor (CD14) and myocardial infarction. New evidence for a role of gram-negative bacterial infection? Circulation. 1999 Jun 29; 99(25):3210-2. Kane JP, Havel RJ. PMID: 10385489.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    115. The apolipoprotein B R3531C mutation. Characteristics of 24 subjects from 9 kindreds. J Lipid Res. 1999 Feb; 40(2):318-27. Pullinger CR, Gaffney D, Gutierrez MM, Malloy MJ, Schumaker VN, Packard CJ, Kane JP. PMID: 9925662.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    116. A multilocus genotyping assay for cardiovascular disease. Clin Chem Lab Med. 1998 Aug; 36(8):561-6. Cheng S, Pallaud C, Grow MA, Scharf SJ, Erlich HA, Klitz W, Pullinger CR, Malloy MJ, Kane JP, Siest G, Visvikis S. PMID: 9806460.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    117. Rationale and design of the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study that evaluates atorvastatin in unstable angina pectoris and in non-Q-wave acute myocardial infarction. Am J Cardiol. 1998 Mar 01; 81(5):578-81. Schwartz GG, Oliver MF, Ezekowitz MD, Ganz P, Waters D, Kane JP, Texter M, Pressler ML, Black D, Chaitman BR, Olsson AG. PMID: 9514453.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    118. Prebeta-1 HDL in plasma of normolipidemic individuals: influences of plasma lipoproteins, age, and gender. J Lipid Res. 1998 Mar; 39(3):670-8. O'Connor PM, Zysow BR, Schoenhaus SA, Ishida BY, Kunitake ST, Naya-Vigne JM, Duchateau PN, Redberg RF, Spencer SJ, Mark S, Mazur M, Heilbron DC, Jaffe RB, Malloy MJ, Kane JP. PMID: 9548598.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    119. Aggressive medical therapy for the prevention and treatment of coronary artery disease. Dis Mon. 1998 Jan; 44(1):1-40. Malloy MJ, Kane JP. PMID: 9457050.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    120. Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. Circulation. 1997 Nov 18; 96(10):3774-7. Sudhir K, Chou TM, Chatterjee K, Smith EP, Williams TC, Kane JP, Malloy MJ, Korach KS, Rubanyi GM. PMID: 9396482.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    121. Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L. J Biol Chem. 1997 Oct 10; 272(41):25576-82. Duchateau PN, Pullinger CR, Orellana RE, Kunitake ST, Naya-Vigne J, O'Connor PM, Malloy MJ, Kane JP. PMID: 9325276.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    122. Measurement of prebeta-1 HDL in human plasma by an ultrafiltration-isotope dilution technique. Anal Biochem. 1997 Sep 05; 251(2):234-40. O'Connor PM, Naya-Vigne JM, Duchateau PN, Ishida BY, Mazur M, Schoenhaus SA, Zysow BR, Malloy MJ, Kunitake ST, Kane JP. PMID: 9299021.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    123. Isolation of subpopulations of high density lipoproteins: three particle species containing apoE and two species devoid of apoE that have affinity for heparin. J Lipid Res. 1997 Sep; 38(9):1859-68. Hennessy LK, Kunitake ST, Jarvis M, Hamilton RL, Endeman G, Protter A, Kane JP. PMID: 9323595.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    124. A novel apolipoprotein C-III variant, apoC-III(Gln38-->Lys), associated with moderate hypertriglyceridemia in a large kindred of Mexican origin. J Lipid Res. 1997 Sep; 38(9):1833-40. Pullinger CR, Malloy MJ, Shahidi AK, Ghassemzadeh M, Duchateau P, Villagomez J, Allaart J, Kane JP. PMID: 9323592.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    125. A single copy of apolipoprotein B-48 is present on the human chylomicron remnant. J Lipid Res. 1997 Jun; 38(6):1170-7. Phillips ML, Pullinger C, Kroes I, Kroes J, Hardman DA, Chen G, Curtiss LK, Gutierrez MM, Kane JP, Schumaker VN. PMID: 9215545.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    126. Cryo-electron microscopy of low density lipoprotein and reconstituted discoidal high density lipoprotein: imaging of the apolipoprotein moiety. J Lipid Res. 1997 Apr; 38(4):659-69. van Antwerpen R, Chen GC, Pullinger CR, Kane JP, LaBelle M, Krauss RM, Luna-Chavez C, Forte TM, Gilkey JC. PMID: 9144081.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    127. Aggressive medical therapy for the prevention and treatment of coronary artery disease. Adv Intern Med. 1997; 42:1-38. Malloy MJ, Kane JP. PMID: 9048115.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    128. The apolipoprotein B Q3405E polymorphism has no effect on its low-density-lipoprotein receptor binding affinity. Hum Genet. 1996 Dec; 98(6):678-80. Pullinger CR, Love JA, Liu W, Hennessy LK, Ghassemzadeh M, Newcomb KC, Illingworth DR, Kane JP. PMID: 8931699.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    129. Angiographically silent atherosclerosis detected by intravascular ultrasound in patients with familial hypercholesterolemia and familial combined hyperlipidemia: correlation with high density lipoproteins. J Am Coll Cardiol. 1996 Jun; 27(7):1562-70. Hausmann D, Johnson JA, Sudhir K, Mullen WL, Friedrich G, Fitzgerald PJ, Chou TM, Ports TA, Kane JP, Malloy MJ, Yock PG. PMID: 8636537.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    130. Identification of apolipoprotein B100 polymorphisms that affect low-density lipoprotein metabolism: description of a new approach involving monoclonal antibodies and dynamic light scattering. Biochemistry. 1995 Jul 25; 34(29):9571-80. Chatterton JE, Schlapfer P, Bütler E, Gutierrez MM, Puppione DL, Pullinger CR, Kane JP, Curtiss LK, Schumaker VN. PMID: 7626627.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    131. Triglyceride-rich lipoproteins prevent septic death in rats. J Exp Med. 1995 Jul 01; 182(1):267-72. Read TE, Grunfeld C, Kumwenda ZL, Calhoun MC, Kane JP, Feingold KR, Rapp JH. PMID: 7790821; PMCID: PMC2192094.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    132. Familial ligand-defective apolipoprotein B. Identification of a new mutation that decreases LDL receptor binding affinity. J Clin Invest. 1995 Mar; 95(3):1225-34. Pullinger CR, Hennessy LK, Chatterton JE, Liu W, Love JA, Mendel CM, Frost PH, Malloy MJ, Schumaker VN, Kane JP. PMID: 7883971; PMCID: PMC441461.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    133. Increased prevalence of coronary ectasia in heterozygous familial hypercholesterolemia. Circulation. 1995 Mar 01; 91(5):1375-80. Sudhir K, Ports TA, Amidon TM, Goldberger JJ, Bhushan V, Kane JP, Yock P, Malloy MJ. PMID: 7867176.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    134. The effects of colestipol tablets compared with colestipol granules on plasma cholesterol and other lipids in moderately hypercholesterolemic patients. Atherosclerosis. 1995 Jan 20; 112(2):223-35. Insull W, Davidson MH, Demke DM, Dujovne CA, Eckert SM, Ginsberg D, Goldberg AC, Hodis HN, Hughes TA, Kane JP, et al. PMID: 7772081.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    135. Triglyceride-rich lipoproteins improve survival when given after endotoxin in rats. Surgery. 1995 Jan; 117(1):62-7. Read TE, Grunfeld C, Kumwenda Z, Calhoun MC, Kane JP, Feingold KR, Rapp JH. PMID: 7809838.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    136. Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. Arterioscler Thromb. 1994 Nov; 14(11):1767-74. Rapp JH, Lespine A, Hamilton RL, Colyvas N, Chaumeton AH, Tweedie-Hardman J, Kotite L, Kunitake ST, Havel RJ, Kane JP. PMID: 7947602.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    137. Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J Exp Med. 1994 Sep 01; 180(3):1025-35. Wurfel MM, Kunitake ST, Lichenstein H, Kane JP, Wright SD. PMID: 8064223; PMCID: PMC2191628.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansCells
    138. The apolipoprotein C-II variant apoC-IILys19-->Thr is not associated with dyslipidemia in an affected kindred. Clin Genet. 1994 Jun; 45(6):292-7. Zysow BR, Pullinger CR, Hennessy LK, Farese RV, Ghassemzadeh M, Kane JP. PMID: 7923858.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    139. Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption. Biochemistry. 1994 Mar 01; 33(8):1988-93. Kunitake ST, Carilli CT, Lau K, Protter AA, Naya-Vigne J, Kane JP. PMID: 8117655.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    140. Medical management of hyperlipidemic states. Adv Intern Med. 1994; 39:603-31. Malloy MJ, Kane JP. PMID: 8140966.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    141. The protective effect of serum lipoproteins against bacterial lipopolysaccharide. Eur Heart J. 1993 Dec; 14 Suppl K:125-9. Read TE, Harris HW, Grunfeld C, Feingold KR, Kane JP, Rapp JH. PMID: 8131781.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    142. Exploratory data analysis of hyperlipidemia on the Macintosh: software tools for analysis of biochemical, clinical, and genetic variables in 1677 consecutive lipid clinic patients. J Med Syst. 1993 Aug; 17(3-4):187-93. Bhushan V, Malloy MJ, Engler MM, Engler MB, Drown D, Kane JP. PMID: 8254263.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    143. Chylomicrons enhance endotoxin excretion in bile. Infect Immun. 1993 Aug; 61(8):3496-502. Read TE, Harris HW, Grunfeld C, Feingold KR, Calhoun MC, Kane JP, Rapp JH. PMID: 8335381; PMCID: PMC281028.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    144. Apolipoprotein A-I-containing lipoproteins, with or without apolipoprotein A-II, as progenitors of pre-beta high-density lipoprotein particles. Biochemistry. 1993 Jun 08; 32(22):5759-65. Hennessy LK, Kunitake ST, Kane JP. PMID: 8504094.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    145. Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. J Clin Invest. 1993 Mar; 91(3):1028-34. Harris HW, Grunfeld C, Feingold KR, Read TE, Kane JP, Jones AL, Eichbaum EB, Bland GF, Rapp JH. PMID: 8450032; PMCID: PMC288056.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    146. Molecular cloning and characteristics of a new apolipoprotein C-II mutant identified in three unrelated individuals with hypercholesterolemia and hypertriglyceridemia. Hum Mol Genet. 1993 Jan; 2(1):69-74. Pullinger CR, Zysow BR, Hennessy LK, Frost PH, Malloy MJ, Kane JP. PMID: 8490626.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    147. Binding of transition metals by apolipoprotein A-I-containing plasma lipoproteins: inhibition of oxidation of low density lipoproteins. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):6993-7. Kunitake ST, Jarvis MR, Hamilton RL, Kane JP. PMID: 1495991; PMCID: PMC49631.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    148. Two apolipoprotein B gene defects in a kindred with hypobetalipoproteinemia, one of which results in a truncated variant, apoB-61, in VLDL and LDL. J Lipid Res. 1992 May; 33(5):699-710. Pullinger CR, Hillas E, Hardman DA, Chen GC, Naya-Vigne JM, Iwasa JA, Hamilton RL, Lalouel JM, Williams RR, Kane JP. PMID: 1619363.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    149. A polymorphic PstI site in intron 2 of the human apolipoprotein C-II gene detected by polymerase chain reaction. Hum Genet. 1992 May; 89(3):361. Zysow BR, Pullinger CR, Kane JP. PMID: 1351041.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    150. Relation of plasma lipid and apoprotein levels to progressive intimal hyperplasia after arterial endarterectomy. Circulation. 1992 Apr; 85(4):1286-92. Colyvas N, Rapp JH, Phillips NR, Stoney R, Perez S, Kane JP, Havel RJ. PMID: 1555272.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    151. Drs malloy and kane respond. West J Med. 1992 Feb; 156(2):209. Malloy MJ, Kane JP. PMID: 18750862; PMCID: PMC1003217.
      View in: PubMed   Mentions:    Fields:    
    152. Chylomicrons can inhibit endotoxin activity in vitro. J Surg Res. 1991 Nov; 51(5):413-6. Eichbaum EB, Harris HW, Kane JP, Rapp JH. PMID: 1758174.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    153. Molecular and metabolic basis for the metabolic disorder normotriglyceridemic abetalipoproteinemia. J Clin Invest. 1991 Nov; 88(5):1722-9. Hardman DA, Pullinger CR, Hamilton RL, Kane JP, Malloy MJ. PMID: 1939657; PMCID: PMC295713.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    154. Niacin--the long and the short of it. West J Med. 1991 Oct; 155(4):424-6. Malloy MJ, Frost PH, Kane JP. PMID: 1771892; PMCID: PMC1003039.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    155. Detection of endotoxin in triglyceride-rich lipoproteins in vitro. J Lab Clin Med. 1991 Aug; 118(2):186-93. Harris HW, Eichbaum EB, Kane JP, Rapp JH. PMID: 1856581.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    156. Differences in local conformation in human apolipoprotein B-100 of plasma low density and very low density lipoproteins as identified by cathepsin D. J Biol Chem. 1991 Jul 05; 266(19):12581-7. Chen GC, Lau K, Hamilton RL, Kane JP. PMID: 2061328.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    157. Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene. J Clin Invest. 1991 Apr; 87(4):1165-70. Ameis D, Kobayashi J, Davis RC, Ben-Zeev O, Malloy MJ, Kane JP, Lee G, Wong H, Havel RJ, Schotz MC. PMID: 2010533; PMCID: PMC295125.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    158. Two apolipoprotein E5 variants illustrate the importance of the position of additional positive charge on receptor-binding activity. J Lipid Res. 1991 Mar; 32(3):521-8. Wardell MR, Rall SC, Schaefer EJ, Kane JP, Weisgraber KH. PMID: 1648586.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    159. Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens. JAMA. 1990 Dec 19; 264(23):3007-12. Kane JP, Malloy MJ, Ports TA, Phillips NR, Diehl JC, Havel RJ. PMID: 2243428.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCTClinical Trials
    160. Conformation of apolipoprotein B-100 in the low density lipoproteins of tangier disease. Identification of localized conformational response to triglyceride content. J Biol Chem. 1990 Dec 05; 265(34):20739-46. Kunitake ST, Young SG, Chen GC, Pullinger CR, Zhu S, Pease RJ, Scott J, Hass P, Schilling J, Kane JP. PMID: 1701170.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    161. Pre-beta high density lipoprotein. Unique disposition of apolipoprotein A-I increases susceptibility to proteolysis. Arteriosclerosis. 1990 Jan-Feb; 10(1):25-30. Kunitake ST, Chen GC, Kung SF, Schilling JW, Hardman DA, Kane JP. PMID: 2136993.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    162. Treatment of hyperlipidemia. Annu Rev Med. 1990; 41:471-82. Kane JP, Malloy MJ. PMID: 2184745.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    163. Structural domains of human apolipoprotein B-100. Differential accessibility to limited proteolysis of B-100 in low density and very low density lipoproteins. J Biol Chem. 1989 Aug 25; 264(24):14369-75. Chen GC, Zhu S, Hardman DA, Schilling JW, Lau K, Kane JP. PMID: 2668286.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    164. Distribution of lipid-binding regions in human apolipoprotein B-100. Biochemistry. 1989 Mar 21; 28(6):2477-84. Chen GC, Hardman DA, Hamilton RL, Mendel CM, Schilling JW, Zhu S, Lau K, Wong JS, Kane JP. PMID: 2730877.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    165. Particle size distribution of lipoproteins from human atherosclerotic plaque: a preliminary report. J Vasc Surg. 1989 Jan; 9(1):81-8. Rapp JH, Harris HW, Hamilton RL, Krupski WC, Reilly LM, Ehrenfeld WK, Stoney RJ, Goldstone J, Kane JP. PMID: 2911145.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    166. Neutralization of mouse xenotropic virus by lipoproteins involves binding to the virions. J Gen Virol. 1988 Oct; 69 ( Pt 10):2657-61. Sernatinger J, Hoffman A, Hardman D, Kane JP, Levy JA. PMID: 2844973.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    167. Radiation inactivation of binding sites for high-density lipoproteins in human liver membranes. Biochim Biophys Acta. 1988 Jul 22; 961(2):188-93. Mendel CM, Kunitake ST, Hong K, Erickson SK, Kane JP, Kempner ES. PMID: 2839235.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    168. Bsm I RFLP at the human apolipoprotein AI-CIII gene complex locus. Nucleic Acids Res. 1988 Mar 25; 16(5):2364. Coleman RT, Cawthon RM, Malloy MJ, Kane JP, Nakashima PF, Frossard PM. PMID: 2895918; PMCID: PMC338250.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    169. NcoI dimorphic site located 8kb 3' to the human apolipoprotein AIV (APOA4) gene. Nucleic Acids Res. 1988 Feb 11; 16(3):1222. Coleman RT, Malloy MJ, Kane JP, Frossard PM. PMID: 2894008; PMCID: PMC334771.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    170. Determinants of kallikrein proteolysis of apolipoprotein B-100 in human blood plasma. Eur J Clin Invest. 1988 Feb; 18(1):75-80. Gustafson A, Kane JP, Havel RJ. PMID: 3130263.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    171. Radiation inactivation of binding sites for high density lipoproteins in human fibroblast membranes. J Biol Chem. 1988 Jan 25; 263(3):1314-9. Mendel CM, Kunitake ST, Kane JP, Kempner ES. PMID: 2826475.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    172. When to treat hyperlipidemia. Adv Intern Med. 1988; 33:143-63. Kane JP, Malloy MJ. PMID: 3278503.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    173. Carboxyl terminal analysis of human B-48 protein confirms the novel mechanism proposed for chain termination. Biochem Biophys Res Commun. 1987 Dec 31; 149(3):1214-9. Hardman DA, Protter AA, Schilling JW, Kane JP. PMID: 3426612.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    174. Complementarity of colestipol, niacin, and lovastatin in treatment of severe familial hypercholesterolemia. Ann Intern Med. 1987 Nov; 107(5):616-23. Malloy MJ, Kane JP, Kunitake ST, Tun P. PMID: 3662275.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    175. Human apolipoprotein CI (apoC1) gene locus: DraI dimorphic site. Nucleic Acids Res. 1987 Feb 25; 15(4):1884. Frossard PM, Coleman RT, Malloy MJ, Kane JP, Levy-Wilson B, Appleby VA. PMID: 2881281; PMCID: PMC340600.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    176. Human apolipoprotein CI (ApoC1) gene locus: BglI dimorphic site. Nucleic Acids Res. 1987 Feb 11; 15(3):1344. Frossard PM, Lim DW, Coleman RT, Funke H, Assmann G, Malloy MJ, Kane JP. PMID: 2881271; PMCID: PMC340542.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    177. DraI RFLP in the human apolipoprotein AI-CIII-AIV gene complex. Nucleic Acids Res. 1986 Nov 11; 14(21):8699. Frossard PM, Coleman RT, Dillan NA, Lim DW, Malloy MJ, Kane JP, Funke H, Assmann G. PMID: 2878415; PMCID: PMC311899.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    178. TaqI and XbaI RFLPs detected with a human apo IV (Apo4) cDNA probe. Nucleic Acids Res. 1986 Oct 10; 14(19):7818. Coleman RT, Dillan NA, Lim DW, Malloy MJ, Kane JP, Frossard PM. PMID: 2877436; PMCID: PMC311808.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    179. Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in patients with familial dysbetalipoproteinemia. J Clin Invest. 1986 Sep; 78(3):722-8. Stalenhoef AF, Malloy MJ, Kane JP, Havel RJ. PMID: 3745433; PMCID: PMC423660.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    180. Analysis of cDNA clones encoding the entire B-26 region of human apolipoprotein B. Proc Natl Acad Sci U S A. 1986 Aug; 83(15):5678-82. Protter AA, Hardman DA, Sato KY, Schilling JW, Yamanaka M, Hort YJ, Hjerrild KA, Chen GC, Kane JP. PMID: 3461454; PMCID: PMC386352.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    181. Scission of human apolipoprotein B-100 by kallikrein: characterization of the cleavage site. Biochem Biophys Res Commun. 1986 Jun 13; 137(2):821-5. Hardman DA, Gustafson A, Schilling JW, Donaldson VH, Kane JP. PMID: 3637099.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    182. A variant primary structure of apolipoprotein C-II in individuals of African descent. J Clin Invest. 1986 Feb; 77(2):595-601. Menzel HJ, Kane JP, Malloy MJ, Havel RJ. PMID: 3944271; PMCID: PMC423392.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    183. Discrimination between subclasses of human high-density lipoproteins by the HDL binding sites of bovine liver. Biochim Biophys Acta. 1986 Jan 03; 875(1):59-68. Mendel CM, Kunitake ST, Kane JP. PMID: 3000454.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    184. Speciation of HDL. Adv Exp Med Biol. 1986; 201:29-35. Kane JP. PMID: 3541521.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    185. Treatment of hypercholesterolemia. Annu Rev Med. 1986; 37:427-35. Kane JP, Havel RJ. PMID: 3518611.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    186. Apolipoprotein A-I-containing lipoproteins with pre-beta electrophoretic mobility. J Lipid Res. 1985 May; 26(5):549-55. Kunitake ST, La Sala KJ, Kane JP. PMID: 3926924.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    187. Circular dichroic spectra of apolipoprotein E in model complexes and cholesterol-rich lipoproteins: lipid contribution. Biochemistry. 1984 Dec 18; 23(26):6530-8. Chen GC, Guo LS, Hamilton RL, Gordon V, Richards EG, Kane JP. PMID: 6529567.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    188. Thermal behavior of cores of human serum triglyceride-rich lipoproteins: a study of induced circular dichroism of beta-carotene. Biochemistry. 1984 Mar 13; 23(6):1119-24. Chen GC, Kane JP, Hamilton RL. PMID: 6712939.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    189. Characteristics of human lipoproteins isolated by selected-affinity immunosorption of apolipoprotein A-I. Proc Natl Acad Sci U S A. 1984 Mar; 81(5):1356-60. McVicar JP, Kunitake ST, Hamilton RL, Kane JP. PMID: 6424116; PMCID: PMC344832.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    190. Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in normal and lipoprotein lipase-deficient humans. Proc Natl Acad Sci U S A. 1984 Mar; 81(6):1839-43. Stalenhoef AF, Malloy MJ, Kane JP, Havel RJ. PMID: 6584917; PMCID: PMC345017.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    191. Sex-related differences in the concentrations of apolipoprotein E in human blood plasma and plasma lipoproteins. J Lipid Res. 1983 Nov; 24(11):1525-31. Phillips NR, Havel RJ, Kane JP. PMID: 6655368.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    192. Secretion of lipoproteins from the liver of normal and Watanabe heritable hyperlipidemic rabbits. Proc Natl Acad Sci U S A. 1983 Oct; 80(19):6096-100. Hornick CA, Kita T, Hamilton RL, Kane JP, Havel RJ. PMID: 6577469; PMCID: PMC534367.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    193. Apolipoprotein and size heterogeneity in human umbilical cord blood low density lipoproteins. Biochim Biophys Acta. 1983 Sep 20; 753(2):186-94. Davis PA, Forte TM, Kane JP, Hardman DA, Krauss RM, Blum CB. PMID: 6615856.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    194. Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3. J Clin Invest. 1983 Jul; 72(1):379-87. Havel RJ, Kotite L, Kane JP, Tun P, Bersot T. PMID: 6860421; PMCID: PMC1129193.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    195. Cholesterol net transport, esterification, and transfer in human hyperlipidemic plasma. J Clin Invest. 1983 Mar; 71(3):449-60. Fielding PE, Fielding CJ, Havel RJ, Kane JP, Tun P. PMID: 6826717; PMCID: PMC436892.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    196. Apolipoprotein B: structural and metabolic heterogeneity. Annu Rev Physiol. 1983; 45:637-50. Kane JP. PMID: 6342527.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    197. Remnants of lipoproteins of intestinal and hepatic origin in familial dysbetalipoproteinemia. Arteriosclerosis. 1983 Jan-Feb; 3(1):47-56. Kane JP, Chen GC, Hamilton RL, Hardman DA, Malloy MJ, Havel RJ. PMID: 6824496.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    198. Concentration and composition of lipoproteins in blood plasma of the WHHL rabbit. An animal model of human familial hypercholesterolemia. Arteriosclerosis. 1982 Nov-Dec; 2(6):467-74. Havel RJ, Kita T, Kotite L, Kane JP, Hamilton RL, Goldstein JL, Brown MS. PMID: 6960858.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    199. Factors affecting the integrity of high density lipoproteins in the ultracentrifuge. J Lipid Res. 1982 Aug; 23(6):936-40. Kunitake ST, Kane JP. PMID: 6813413.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    200. Serum apolipoprotein A-I levels: relationship to lipoprotein lipid levels and selected demographic variables. Am J Epidemiol. 1982 Aug; 116(2):302-13. Phillips NR, Havel RJ, Kane JP. PMID: 6810694.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    201. Characterization and quantitation of apolipoproteins A-I and E of normal and cholesterol-fed guinea pigs. J Lipid Res. 1982 May; 23(4):531-42. Guo LS, Hamilton RL, Kane JP, Fielding CJ, Chen GC. PMID: 7182951.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    202. Transfer of mouse anti-xenotropic virus neutralizing factor to human lipoproteins. J Virol. 1982 May; 42(2):365-71. Levy JA, Dimpfl J, Hardman D, Kane JP. PMID: 6283160; PMCID: PMC256861.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    203. Hypolipidemia. Med Clin North Am. 1982 Mar; 66(2):469-84. Malloy MJ, Kane JP. PMID: 7040848.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    204. Treatment of hypercholesterolemia. Med Clin North Am. 1982 Mar; 66(2):537-50. Kane JP, Malloy MJ. PMID: 7040850.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    205. Therapy of hyperlipidemic states. Annu Rev Med. 1982; 33:417-33. Havel RJ, Kane JP. PMID: 7044276.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    206. Apolipoprotein B (B-48) of rat chylomicrons is not a precursor of the apolipoprotein of low density lipoproteins. Proc Natl Acad Sci U S A. 1982 Jan; 79(1):179-82. Van't Hooft FM, Hardman DA, Kane JP, Havel RJ. PMID: 6948299; PMCID: PMC345686.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    207. Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows. J Clin Invest. 1981 Oct; 68(4):1075-85. Schneider WJ, Kovanen PT, Brown MS, Goldstein JL, Utermann G, Weber W, Havel RJ, Kotite L, Kane JP, Innerarity TL, Mahley RW. PMID: 6270194; PMCID: PMC370895.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    208. Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein. J Clin Invest. 1981 May; 67(5):1441-50. Malloy MJ, Kane JP, Hardman DA, Hamilton RL, Dalal KB. PMID: 7229035; PMCID: PMC370711.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    209. Normalization of low-density-lipoprotein levels in heterozygous familial hypercholesterolemia with a combined drug regimen. N Engl J Med. 1981 Jan 29; 304(5):251-8. Kane JP, Malloy MJ, Tun P, Phillips NR, Freedman DD, Williams ML, Rowe JS, Havel RJ. PMID: 7003391.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCTClinical Trials
    210. Levels and interrelationships of serum and lipoprotein cholesterol and triglycerides. Association with adiposity and the consumption of ethanol, tobacco, and beverages containing caffeine. Arteriosclerosis. 1981 Jan-Feb; 1(1):13-24. Phillips NR, Havel RJ, Kane JP. PMID: 7295182.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    211. Human apolipoprotein C-I: concentration in blood serum and lipoproteins. Biochem Med. 1980 Dec; 24(3):229-37. Polz E, Kotite L, Havel RJ, Kane JP, Sata T. PMID: 7283981.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    212. Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency. J Clin Invest. 1980 Dec; 66(6):1351-62. Havel RJ, Kotite L, Vigne JL, Kane JP, Tun P, Phillips N, Chen GC. PMID: 7440719; PMCID: PMC371621.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    213. beta-Carotene as a probe of lipid domains of reconstituted human plasma low-density lipoprotein: induced circular dichroism. Biochemistry. 1980 Sep 30; 19(20):4706-12. Chen GC, Krieger M, Kane JP, Wu CS, Brown MS, Goldstein JL. PMID: 7426623.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    214. Pancreatic alpha and beta cell function in familial dysbetalipoproteinemia. Horm Metab Res. 1980 Sep; 12(9):421-5. Tan MH, Havel RJ, Gerich JE, Soeldner JS, Kane JP. PMID: 7000652.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    215. Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons. Proc Natl Acad Sci U S A. 1980 May; 77(5):2465-9. Kane JP, Hardman DA, Paulus HE. PMID: 6930644; PMCID: PMC349420.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    216. Apolipoprotein is responsible for neutralization of xenotropic type C virus by mouse serum. Proc Natl Acad Sci U S A. 1979 Nov; 76(11):5957-61. Kane JP, Hardman DA, Dimpfl JC, Levy JA. PMID: 230495; PMCID: PMC411772.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    217. Secondary structure in very low density and intermediate density lipoproteins of human serum. J Lipid Res. 1979 May; 20(4):481-8. Chen GC, Kane JP. PMID: 222856.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    218. Isoelectric heterogeneity of the cofactor protein for lipoprotein lipase in human blood plasma. Biochem Med. 1979 Feb; 21(1):121-38. Havel RJ, Kotite L, Kane JP. PMID: 222259.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    219. Normocholesterolemic dysbetalipoproteinemia with xanthomatosis. Metabolism. 1979 Feb; 28(2):113-24. Abrams JJ, Grundy SM, Kane JP, Chang CM. PMID: 216881.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    220. Heterogeneity of hemoglobin gamma chains in normal newborns and in cases of alpha and beta thalassemia. Am J Hematol. 1979; 6(1):17-25. Lie-Injo LE, Randhawa ZI, Kane JP, Ganesan J, George R. PMID: 453194.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    221. Molecular weight distributions of polydisperse systems: application to very low density lipoproteins. Biochemistry. 1978 May 16; 17(10):1936-42. Kunitake ST, Loh E, Schumaker VN, Ma SK, Knobler CM, Kane JP, Hamilton RL. PMID: 207303.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    222. Familial hypercholesterolemia in children: treatment with p-aminosalicylic acid. Pediatrics. 1978 Mar; 61(3):365-72. Malloy MJ, Kane JP, Rowe JS. PMID: 205828.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    223. Bladder cancer and squamous metaplasia in spinal cord injury patients. J Urol. 1977 Dec; 118(6):967-71. Kaufman JM, Fam B, Jacobs SC, Gabilondo F, Yalla S, Kane JP, Rossier AB. PMID: 926277.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    224. Characterization of human very low density lipoproteins containing two electrophoretic populations: double pre-beta lipoproteinemia and primary dysbetalipoproteinemia. J Lipid Res. 1977 Sep; 18(5):613-22. Pagnan A, Havel RJ, Kane JP, Kotite L. PMID: 198504.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    225. Hb Leiden-beta (0) thalassemia in a Chinese with severe hemolytic anemia. Am J Hematol. 1977; 2(4):335-42. Lie-Injo LE, Ganesan J, Randhawa ZI, Peterson D, Kane JP. PMID: 602924.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    226. New protein in human blood plasma, rich in proline, with lipid-binding properties. Proc Natl Acad Sci U S A. 1976 Apr; 73(4):1063-7. Sata T, Havel RJ, Kotite L, Kane JP. PMID: 1063389; PMCID: PMC430200.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    227. Effects of a 3-day fast and of ethanol on splanchnic metabolism of FFA, amino acids, and carbohydrates in healthy young men. J Clin Invest. 1976 Feb; 57(2):329-40. Wolfe BM, Havel JR, Marliss EB, Kane JP, Seymour J, Ahuja SP. PMID: 176179; PMCID: PMC436657.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    228. Quantification of triglyceride transport in blood plasma: a critical analysis. Fed Proc. 1975 Dec; 34(13):2250-7. Havel RJ, Kane JP. PMID: 172371.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    229. Metabolism of apoprotein B of plasma very low density lipoproteins in the rat. J Clin Invest. 1975 Dec; 56(6):1396-1403. Faergeman O, Sata T, Kane JP, Havel RJ. PMID: 172530; PMCID: PMC333117.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    230. Apoprotein composition of very low density lipoproteins of human serum. J Clin Invest. 1975 Dec; 56(6):1622-34. Kane JP, Sata T, Hamilton RL, Havel RJ. PMID: 172534; PMCID: PMC333142.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    231. Stability of the apoprotein of human serum low density lipoprotein: absence of endogenous endopeptidase activity. Biochem Biophys Res Commun. 1975 Oct 06; 66(3):1030-6. Chapman MJ, Kane JP. PMID: 170935.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    232. The complement system in cryoglobulinaemia. Interaction with immunoglobulins and lipoproteins. Clin Exp Immunol. 1975 Sep; 21(3):510-9. Linscott WD, Kane JP. PMID: 173488; PMCID: PMC1538309.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    233. Temperature dependence of the optical activity of human serum low density lipoprotein. The role of lipids. Biochemistry. 1975 Jul 29; 14(15):3357-62. Chen GC, Kane JP. PMID: 167825.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    234. Editorial: Early prevention of atherosclerosis. West J Med. 1975 Apr; 122(4):328-9. Kane JP, Malloy MJ. PMID: 1154774; PMCID: PMC1129734.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    235. Contribution of carotenoids to the optical activity of human serum low-density lipoprotein. Biochemistry. 1974 Jul 30; 13(16):3330-5. Chen GC, Kane JP. PMID: 4366472.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    236. Mechanism of the hypolipemic effect of clofibrate in postabsorptive man. J Clin Invest. 1973 Sep; 52(9):2146-59. Wolfe BM, Kane JP, Havel RJ, Brewster HP. PMID: 4353773; PMCID: PMC333015.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    237. Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in triglyceride-rich lipoproteins. Proc Natl Acad Sci U S A. 1973 Jul; 70(7):2015-9. Havel RJ, Kane JP. PMID: 4352966; PMCID: PMC433655.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    238. A rapid electrophoretic technique for identification of subunit species of apoproteins in serum lipoproteins. Anal Biochem. 1973 Jun; 53(2):350-64. Kane JP. PMID: 4351944.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    239. Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man. J Clin Invest. 1973 Jan; 52(1):32-8. Havel RJ, Kane JP, Kashyap ML. PMID: 4345202; PMCID: PMC302224.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    240. Drugs and lipid metabolism. Annu Rev Pharmacol. 1973; 13:287-308. Havel RJ, Kane JP. PMID: 4576891.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    241. Cholestasis: lamellar structure of the abnormal human serum lipoprotein. Science. 1971 Apr 30; 172(3982):475-8. Hamilton RL, Havel RJ, Kane JP, Blaurock AE, Sata T. PMID: 5550502.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    242. Splanchnic metabolism of free fatty acids and production of triglycerides of very low density lipoproteins in normotriglyceridemic and hypertriglyceridemic humans. J Clin Invest. 1970 Nov; 49(11):2017-35. Havel RJ, Kane JP, Balasse EO, Segel N, Basso LV. PMID: 5475985; PMCID: PMC535780.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    243. Subunit heterogeneity in human serum beta lipoprotein. Proc Natl Acad Sci U S A. 1970 Aug; 66(4):1075-82. Kane JP, Richards EG, Havel RJ. PMID: 4990876; PMCID: PMC335788.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    244. Splanchnic metabolism in von Gierke's disease (glycogenosis type I). Trans Assoc Am Physicians. 1969; 82:305-23. Havel RJ, Balasse EO, Williams HE, Kane JP, Segel N. PMID: 5375154.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    245. STUDIES OF CARBOHYDRATE METABOLISM IN IDIOPATHIC HYPERTRIGLYCERIDEMIA. Metabolism. 1965 Apr; 14:471-86. KANE JP, LONGCOPE C, PAVLATOS FC, GRODSKY GM. PMID: 14288605.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    246. Sterol biosynthesis under the influence of a thyroxine analog (3,5-diiodothyroacetic acid). Metabolism. 1962 Dec; 11:1310-4. KANE JP, FORSHAM PH. PMID: 13962187.
      View in: PubMed   Mentions:    Fields:    
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