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Laurence Tecott

TitleProfessor
SchoolUCSF School of Medicine
DepartmentPsychiatry
Address1550 4th Street, Bldg 19B
San Francisco CA 94158
Phone415-476-7858
EmailLarry.Tecott@ucsf.edu
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco Residency School of Medicine
    University of California, San FranciscoM.D.1983School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Striatal Circuits In The Serotonergic Modulation Of Hedonic States
    NIH/NIMH R01MH104671Sep 10, 2015 - Jun 30, 2017
    Role: Principal Investigator
    Impact of Energy Status on the Serotonergic Regulation of Energy Balance
    NIH/NIDDK R01DK085472Aug 15, 2010 - Jun 30, 2014
    Role: Principal Investigator
    A Quantitative Approach for Detecting Anxiolytic Drug Effects in the Mouse
    NIH/NIMH R21MH079145Aug 17, 2007 - Jul 31, 2009
    Role: Principal Investigator
    Serotonergic genetic influences on the impact of maternal environment
    NIH/NICHD R21HD051591Mar 15, 2007 - Feb 28, 2009
    Role: Principal Investigator
    Management and Analysis of Mouse Behavioral Datasets
    NIH/NIMH R01MH077128Jan 24, 2007 - Dec 31, 2009
    Role: Principal Investigator
    INGESTIVE BEHAVIOR IN SEROTONIN RECEPTOR MUTANT MICE
    NIH/NIMH K02MH001949Sep 1, 2000 - Feb 28, 2006
    Role: Principal Investigator
    GENETIC APPROACHES TO SEROTONIN AND FEEDING BEHAVIOR
    NIH/NIMH R01MH061624Jun 1, 2000 - May 31, 2006
    Role: Principal Investigator
    SEROTONIN 5HT2C RECEPTORS AND THE ACTIONS OF COCAINE
    NIH/NIDA R01DA011177Aug 1, 1998 - Jun 30, 2002
    Role: Principal Investigator
    MODELS TO ANALYZE SEROTONIN RECEPTOR FUNCTIONS
    NIH/NIDA K21DA000282Jul 15, 1995 - Jun 30, 2000
    Role: Principal Investigator
    OPIATES AND NEURONAL SUBSTRATES OF ASSOCIATIVE LEARNING
    NIH/NIMH F32MH009099Oct 1, 1984
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bonasera SJ, Arikkath J, Boska MD, Chaudoin TR, DeKorver NW, Goulding EH, Hoke TA, Mojtahedzedah V, Reyelts CD, Sajja B, Schenk AK, Tecott L, Volden TA. Age-related changes in cerebellar and hypothalamic function accompany non-microglial immune gene expression, altered synapse organization, and excitatory amino acid neurotransmission deficits. Aging (Albany NY). 2016 Sep 20; 8(9):2153-2181. PMID: 27689748.
      View in: PubMed
    2. Bonasera SJ, Schenk AK, Luxenberg EJ, Wang X, Basbaum A, Tecott L. Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli. PLoS One. 2015; 10(12):e0142906. PMID: 26630489; PMCID: PMC4667991.
    3. Urban DJ, Zhu H, Marcinkiewcz CA, Michaelides M, Oshibuchi H, Rhea D, Aryal DK, Farrell MS, Lowery-Gionta E, Olsen RH, Wetsel WC, Kash TL, Hurd YL, Tecott L, Roth BL. Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons. Neuropsychopharmacology. 2016 Apr; 41(5):1404-15. PMID: 26383016; PMCID: PMC4793125 [Available on 04/01/17].
    4. Berger M, Scheel DW, Macias H, Miyatsuka T, Kim H, Hoang P, Ku GM, Honig G, Liou A, Tang Y, Regard JB, Sharifnia P, Yu L, Wang J, Coughlin SR, Conklin BR, Deneris ES, Tecott L, German MS. Gai/o-coupled receptor signaling restricts pancreatic ß-cell expansion. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):2888-93. PMID: 25695968; PMCID: PMC4352814.
    5. Tong CK, Chen J, Cebrián-Silla A, Mirzadeh Z, Obernier K, Guinto CD, Tecott L, García-Verdugo JM, Kriegstein A, Alvarez-Buylla A. Axonal control of the adult neural stem cell niche. Cell Stem Cell. 2014 Apr 03; 14(4):500-11. PMID: 24561083; PMCID: PMC4080817.
    6. Donovan MH, Tecott L. Serotonin and the regulation of mammalian energy balance. Front Neurosci. 2013; 7:36. PMID: 23543912; PMCID: PMC3608917.
    7. Pennanen L, van der Hart M, Yu L, Tecott L. Impact of serotonin (5-HT)2C receptors on executive control processes. Neuropsychopharmacology. 2013 May; 38(6):957-67. PMID: 23303047; PMCID: PMC3629384.
    8. Ohta Y, Kosaka Y, Kishimoto N, Wang J, Smith SB, Honig G, Kim H, Gasa RM, Neubauer N, Liou A, Tecott L, Deneris ES, German MS. Convergence of the insulin and serotonin programs in the pancreatic ß-cell. Diabetes. 2011 Dec; 60(12):3208-16. PMID: 22013016; PMCID: PMC3219954.
    9. Xiong H, Goulding EH, Carlson EJ, Tecott L, McCulloch CE, Sen S. A flexible estimating equations approach for mapping function-valued traits. Genetics. 2011 Sep; 189(1):305-16. PMID: 21705752; PMCID: PMC3176135.
    10. Urban R, Scherrer G, Goulding EH, Tecott L, Basbaum AI. Behavioral indices of ongoing pain are largely unchanged in male mice with tissue or nerve injury-induced mechanical hypersensitivity. Pain. 2011 May; 152(5):990-1000. PMID: 21256675; PMCID: PMC3079194.
    11. Honig G, Liou A, Berger M, German MS, Tecott L. Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line. J Biomed Sci. 2010 Oct 17; 17:82. PMID: 20950489; PMCID: PMC2966455.
    12. Oury F, Yadav VK, Wang Y, Zhou B, Liu XS, Guo XE, Tecott L, Schutz G, Means AR, Karsenty G. CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons. Genes Dev. 2010 Oct 15; 24(20):2330-42. PMID: 20952540; PMCID: PMC2956211.
    13. Hsu JL, Yu L, Sullivan E, Bowman M, Mistlberger RE, Tecott L. Enhanced food anticipatory activity associated with enhanced activation of extrahypothalamic neural pathways in serotonin2C receptor null mutant mice. PLoS One. 2010 Jul 27; 5(7):e11802. PMID: 20668550; PMCID: PMC2910710.
    14. Kim H, Toyofuku Y, Lynn FC, Chak E, Uchida T, Mizukami H, Fujitani Y, Kawamori R, Miyatsuka T, Kosaka Y, Yang K, Honig G, van der Hart M, Kishimoto N, Wang J, Yagihashi S, Tecott L, Watada H, German MS. Serotonin regulates pancreatic beta cell mass during pregnancy. Nat Med. 2010 Jul; 16(7):804-8. PMID: 20581837; PMCID: PMC2921604.
    15. Mikulski Z, Zaslona Z, Cakarova L, Hartmann P, Wilhelm J, Tecott L, Lohmeyer J, Kummer W. Serotonin activates murine alveolar macrophages through 5-HT2C receptors. Am J Physiol Lung Cell Mol Physiol. 2010 Aug; 299(2):L272-80. PMID: 20495077.
      View in: PubMed
    16. Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott L, Mann JJ, Hen R, Horvath TL, Karsenty G. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell. 2009 Sep 04; 138(5):976-89. PMID: 19737523; PMCID: PMC2768582.
    17. Honig G, Jongsma ME, van der Hart MC, Tecott L. Chronic citalopram administration causes a sustained suppression of serotonin synthesis in the mouse forebrain. PLoS One. 2009 Aug 27; 4(8):e6797. PMID: 19710918; PMCID: PMC2728775.
    18. Mao R, Page DT, Merzlyak I, Kim C, Tecott L, Janak PH, Rubenstein JL, Sur M. Reduced conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of interneurons. J Neurodev Disord. 2009 Sep; 1(3):224-36. PMID: 19816534.
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    19. Abdallah L, Bonasera SJ, Hopf FW, O'Dell L, Giorgetti M, Jongsma M, Carra S, Pierucci M, Di Giovanni G, Esposito E, Parsons LH, Bonci A, Tecott L. Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function. J Neurosci. 2009 Jun 24; 29(25):8156-65. PMID: 19553455; PMCID: PMC3077993.
    20. Goulding EH, Schenk AK, Juneja P, MacKay AW, Wade JM, Tecott L. A robust automated system elucidates mouse home cage behavioral structure. Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52):20575-82. PMID: 19106295; PMCID: PMC2634928.
    21. Fyffe SL, Neul JL, Samaco RC, Chao HT, Ben-Shachar S, Moretti P, McGill BE, Goulding EH, Sullivan E, Tecott L, Zoghbi HY. Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress. Neuron. 2008 Sep 25; 59(6):947-58. PMID: 18817733; PMCID: PMC2597031.
    22. Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA, Cook EH, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott L, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biol Psychiatry. 2008 Apr 15; 63(8):725-7. PMID: 18371494.
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    23. Casper RC, Sullivan EL, Tecott L. Relevance of animal models to human eating disorders and obesity. Psychopharmacology (Berl). 2008 Aug; 199(3):313-29. PMID: 18317734.
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    24. Scott-McKean JJ, Wenger GR, Tecott L, Costa AC. 5-HT(1A) Receptor Null Mutant Mice Responding Under a Differential-Reinforcement-of-Low-Rate 72-Second Schedule of Reinforcement. Open Neuropsychopharmacol J. 2008 Jan 01; 1:24-32. PMID: 20352018.
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    25. Bonasera SJ, Schenk AK, Luxenberg EJ, Tecott L. A novel method for automatic quantification of psychostimulant-evoked route-tracing stereotypy: application to Mus musculus. Psychopharmacology (Berl). 2008 Mar; 196(4):591-602. PMID: 18097652; PMCID: PMC2562621.
    26. Wade JM, Juneja P, MacKay AW, Graham J, Havel PJ, Tecott L, Goulding EH. Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors. Endocrinology. 2008 Mar; 149(3):955-61. PMID: 18039786; PMCID: PMC2275362.
    27. Tecott L. Serotonin and the orchestration of energy balance. Cell Metab. 2007 Nov; 6(5):352-61. PMID: 17983581.
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    28. Heisler LK, Pronchuk N, Nonogaki K, Zhou L, Raber J, Tung L, Yeo GS, O'Rahilly S, Colmers WF, Elmquist JK, Tecott L. Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation. J Neurosci. 2007 Jun 27; 27(26):6956-64. PMID: 17596444.
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    29. Heisler LK, Zhou L, Bajwa P, Hsu J, Tecott L. Serotonin 5-HT(2C) receptors regulate anxiety-like behavior. Genes Brain Behav. 2007 Jul; 6(5):491-6. PMID: 17451451.
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    30. Zhang J, Pho V, Bonasera SJ, Holtzman J, Tang AT, Hellmuth J, Tang S, Janak PH, Tecott L, Huang EJ. Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons. Nat Neurosci. 2007 Jan; 10(1):77-86. PMID: 17159989; PMCID: PMC3578579.
    31. O'Connell TD, Swigart PM, Rodrigo MC, Ishizaka S, Joho S, Turnbull L, Tecott L, Baker AJ, Foster E, Grossman W, Simpson PC. Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload. J Clin Invest. 2006 Apr; 116(4):1005-15. PMID: 16585965; PMCID: PMC1421341.
    32. Bonasera SJ, Chu HM, Brennan TJ, Tecott L. A null mutation of the serotonin 6 receptor alters acute responses to ethanol. Neuropsychopharmacology. 2006 Aug; 31(8):1801-13. PMID: 16452990.
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    33. Kushwaha N, Harwood SC, Wilson AM, Berger M, Tecott L, Roth BL, Albert PR. Molecular determinants in the second intracellular loop of the 5-hydroxytryptamine-1A receptor for G-protein coupling. Mol Pharmacol. 2006 May; 69(5):1518-26. PMID: 16410407.
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    34. Storm EE, Tecott L. Social circuits: peptidergic regulation of mammalian social behavior. Neuron. 2005 Aug 18; 47(4):483-6. PMID: 16102531.
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    35. Cannon CM, Abdallah L, Tecott L, During MJ, Palmiter RD. Dysregulation of striatal dopamine signaling by amphetamine inhibits feeding by hungry mice. Neuron. 2004 Oct 28; 44(3):509-20. PMID: 15504330.
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    36. Cremers TI, Giorgetti M, Bosker FJ, Hogg S, Arnt J, Mørk A, Honig G, Bøgesø KP, Westerink BH, den Boer H, Wikstrom HV, Tecott L. Inactivation of 5-HT(2C) receptors potentiates consequences of serotonin reuptake blockade. Neuropsychopharmacology. 2004 Oct; 29(10):1782-9. PMID: 15138437.
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    37. Tecott L, Nestler EJ. Neurobehavioral assessment in the information age. Nat Neurosci. 2004 May; 7(5):462-6. PMID: 15114359.
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    38. Giorgetti M, Tecott L. Contributions of 5-HT(2C) receptors to multiple actions of central serotonin systems. Eur J Pharmacol. 2004 Mar 19; 488(1-3):1-9. PMID: 15044029.
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    39. Tecott L, Abdallah L. Mouse genetic approaches to feeding regulation: serotonin 5-HT2C receptor mutant mice. CNS Spectr. 2003 Aug; 8(8):584-8. PMID: 12907921.
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    40. Xu B, Goulding EH, Zang K, Cepoi D, Cone RD, Jones KR, Tecott L, Reichardt LF. Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci. 2003 Jul; 6(7):736-42. PMID: 12796784; PMCID: PMC2710100.
    41. Heisler LK, Cowley MA, Kishi T, Tecott L, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro J, Zigman JM, Cone RD, Elmquist JK. Central serotonin and melanocortin pathways regulating energy homeostasis. Ann N Y Acad Sci. 2003 Jun; 994:169-74. PMID: 12851313.
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    42. Tecott L. The genes and brains of mice and men. Am J Psychiatry. 2003 Apr; 160(4):646-56. PMID: 12668350.
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    43. Nonogaki K, Abdallah L, Goulding EH, Bonasera SJ, Tecott L. Hyperactivity and reduced energy cost of physical activity in serotonin 5-HT(2C) receptor mutant mice. Diabetes. 2003 Feb; 52(2):315-20. PMID: 12540602.
      View in: PubMed
    44. Rocha BA, Goulding EH, O'Dell LE, Mead AN, Coufal NG, Parsons LH, Tecott L. Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice. J Neurosci. 2002 Nov 15; 22(22):10039-45. PMID: 12427861.
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    45. Frank MG, Stryker MP, Tecott L. Sleep and sleep homeostasis in mice lacking the 5-HT2c receptor. Neuropsychopharmacology. 2002 Nov; 27(5):869-73. PMID: 12431861; PMCID: PMC2452994.
    46. Heisler LK, Cowley MA, Tecott L, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK. Activation of central melanocortin pathways by fenfluramine. Science. 2002 Jul 26; 297(5581):609-11. PMID: 12142539.
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    47. Nonogaki K, Memon RA, Grunfeld C, Feingold KR, Tecott L. Altered gene expressions involved in energy expenditure in 5-HT(2C) receptor mutant mice. Biochem Biophys Res Commun. 2002 Jul 12; 295(2):249-54. PMID: 12150939.
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    48. López-Giménez JF, Tecott L, Palacios JM, Mengod G, Vilaró MT. Serotonin 5- HT (2C) receptor knockout mice: autoradiographic analysis of multiple serotonin receptors. J Neurosci Res. 2002 Jan 01; 67(1):69-85. PMID: 11754082.
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    49. Tecott L, Wehner JM. Mouse molecular genetic technologies: promise for psychiatric research. Arch Gen Psychiatry. 2001 Nov; 58(11):995-1004. PMID: 11695945.
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    50. Shekhar A, McCann UD, Meaney MJ, Blanchard DC, Davis M, Frey KA, Liberzon I, Overall KL, Shear MK, Tecott L, Winsky L. Summary of a National Institute of Mental Health workshop: developing animal models of anxiety disorders. Psychopharmacology (Berl). 2001 Oct; 157(4):327-39. PMID: 11605091.
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    51. Ruan Y, Tecott L, Jiang MM, Jan LY, Jan YN. Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9907-12. PMID: 11481456; PMCID: PMC55551.
    52. Parsons LH, Kerr TM, Tecott L. 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission. J Neurochem. 2001 Apr; 77(2):607-17. PMID: 11299323.
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    53. Memon RA, Tecott L, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR. Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice. Endocrinology. 2000 Nov; 141(11):4021-31. PMID: 11089532.
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    54. Bonasera SJ, Tecott L. Mouse models of serotonin receptor function: toward a genetic dissection of serotonin systems. Pharmacol Ther. 2000 Nov; 88(2):133-42. PMID: 11150593.
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    55. Memon RA, Tecott L, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR. Up-Regulation of Peroxisome Proliferator-Activated Receptors (PPAR-a) and PPAR-? Messenger Ribonucleic Acid Expression in the Liver in Murine Obesity: Troglitazone Induces Expression of PPAR-?-Responsive Adipose Tissue-Specific Genes in the Liver of Obese Diabetic Mice* * This work was supported by grants from the Research Service of the Department of Veterans Affairs (to C.G. and K.R.F.), NIH Grant DK-49448 (to C.G.), and Merck Research Laboratories (to L.H.T. and K.N.). Endocrinology. 2000 Nov 01; 141(11):4021-4031. PMID: 28200855.
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    56. Tecott L. Designer genes and anti-anxiety drugs. Nat Neurosci. 2000 Jun; 3(6):529-30. PMID: 10816304.
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    57. Rueter LE, Tecott L, Blier P. In vivo electrophysiological examination of 5-HT2 responses in 5-HT2C receptor mutant mice. Naunyn Schmiedebergs Arch Pharmacol. 2000 May; 361(5):484-91. PMID: 10832601.
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    58. Heisler LK, Tecott L. A paradoxical locomotor response in serotonin 5-HT(2C) receptor mutant mice. J Neurosci. 2000 Apr 15; 20(8):RC71. PMID: 10751458.
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    59. Shelbourne PF, Killeen N, Hevner RF, Johnston HM, Tecott L, Lewandoski M, Ennis M, Ramirez L, Li Z, Iannicola C, Littman DR, Myers RM. A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice. Hum Mol Genet. 1999 May; 8(5):763-74. PMID: 10196365.
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    60. Vickers SP, Clifton PG, Dourish CT, Tecott L. Reduced satiating effect of d-fenfluramine in serotonin 5-HT(2C) receptor mutant mice. Psychopharmacology (Berl). 1999 Apr; 143(3):309-14. PMID: 10353435.
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    61. Heisler LK, Tecott L. Knockout Corner: Neurobehavioural consequences of a serotonin 5-HT(2C) receptor gene mutation. Int J Neuropsychopharmacol. 1999 Mar; 2(1):67-69. PMID: 11281972.
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    62. Kash SF, Tecott L, Hodge C, Baekkeskov S. Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4):1698-703. PMID: 9990087; PMCID: PMC15565.
    63. Toth M, Tecott L. Transgenic approaches to epilepsy. Adv Neurol. 1999; 79:291-6. PMID: 10514821.
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    64. Heisler LK, Chu HM, Tecott L. Epilepsy and obesity in serotonin 5-HT2C receptor mutant mice. Ann N Y Acad Sci. 1998 Dec 15; 861:74-8. PMID: 9928241.
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    65. Tecott L, Heberlein U. Y do we drink? Cell. 1998 Dec 11; 95(6):733-5. PMID: 9865690.
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    66. Tecott L, Logue SF, Wehner JM, Kauer JA. Perturbed dentate gyrus function in serotonin 5-HT2C receptor mutant mice. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):15026-31. PMID: 9844009; PMCID: PMC24569.
    67. Heisler LK, Chu HM, Brennan TJ, Danao JA, Bajwa P, Parsons LH, Tecott L. Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):15049-54. PMID: 9844013; PMCID: PMC24573.
    68. Applegate CD, Tecott L. Global increases in seizure susceptibility in mice lacking 5-HT2C receptors: a behavioral analysis. Exp Neurol. 1998 Dec; 154(2):522-30. PMID: 9878187.
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    69. Nonogaki K, Strack AM, Dallman MF, Tecott L. Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. Nat Med. 1998 Oct; 4(10):1152-6. PMID: 9771748.
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    70. Kash SF, Johnson RS, Tecott L, Noebels JL, Mayfield RD, Hanahan D, Baekkeskov S. Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A. 1997 Dec 09; 94(25):14060-5. PMID: 9391152; PMCID: PMC28432.
    71. Brennan TJ, Seeley WW, Kilgard M, Schreiner CE, Tecott L. Sound-induced seizures in serotonin 5-HT2c receptor mutant mice. Nat Genet. 1997 Aug; 16(4):387-90. PMID: 9241279.
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    72. Tecott L, Barondes SH. Genes and aggressiveness. Behavioral genetics. Curr Biol. 1996 Mar 01; 6(3):238-40. PMID: 8805235.
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    73. Marmar CR, Schoenfeld F, Weiss DS, Metzler T, Zatzick D, Wu R, Smiga S, Tecott L, Neylan T. Open trial of fluvoxamine treatment for combat-related posttraumatic stress disorder. J Clin Psychiatry. 1996; 57 Suppl 8:66-70; discussion 71-2. PMID: 8698684.
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    74. Tecott L, Sun LM, Akana SF, Strack AM, Lowenstein DH, Dallman MF, Julius D. Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors. Nature. 1995 Apr 06; 374(6522):542-6. PMID: 7700379.
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    75. Tecott L, Shtrom S, Julius D. Expression of a serotonin-gated ion channel in embryonic neural and nonneural tissues. Mol Cell Neurosci. 1995 Feb; 6(1):43-55. PMID: 7541286.
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    76. Tecott L, Julius D. A new wave of serotonin receptors. Curr Opin Neurobiol. 1993 Jun; 3(3):310-5. PMID: 8369625.
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    77. Tecott L, Maricq AV, Julius D. Nervous system distribution of the serotonin 5-HT3 receptor mRNA. Proc Natl Acad Sci U S A. 1993 Feb 15; 90(4):1430-4. PMID: 8434003; PMCID: PMC45887.
    78. Milatovich A, Hsieh CL, Bonaminio G, Tecott L, Julius D, Francke U. Serotonin receptor 1c gene assigned to X chromosome in human (band q24) and mouse (bands D-F4). Hum Mol Genet. 1992 Dec; 1(9):681-4. PMID: 1302605.
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    79. Tecott L, Rubenstein JL, Paxinos G, Evans CJ, Eberwine JH, Valentino KL. Developmental expression of proenkephalin mRNA and peptides in rat striatum. Brain Res Dev Brain Res. 1989 Sep 01; 49(1):75-86. PMID: 2791268.
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    80. Tecott L, Barchas JD, Eberwine JH. In situ transcription: specific synthesis of complementary DNA in fixed tissue sections. Science. 1988 Jun 17; 240(4859):1661-4. PMID: 2454508.
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    81. Tecott L, Kwong LL, Uhr S, Peroutka SJ. Differential modulation of dopamine D2 receptors by chronic haloperidol, nitrendipine, and pimozide. Biol Psychiatry. 1986 Oct; 21(12):1114-22. PMID: 2428411.
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    82. Levine JD, Feldmesser M, Tecott L, Lane S, Gordon NC. The role of stimulus intensity and stress in opioid-mediated analgesia. Brain Res. 1984 Jun 25; 304(2):265-9. PMID: 6744043.
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