 Heather Fullerton, MD
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| Title | Associate Professor in Residence |
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| School | UCSF School of Medicine |
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| Department | Neurology |
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| Address | 675 Nelson Rising Lane
San Francisco CA 94158
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| Phone | 415-353-7596 |
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 Overview Dr. Heather Fullerton is pediatric vascular neurologist with an active clinical research program in childhood stroke. She is the Director of the UCSF Pediatric Stroke and Cerebrovascular Disease Center, which she established in 2006, and Director of the UCSF Stroke Sciences Group, a group of stroke investigators first established by Dr. Clay Johnston, an adult stroke neurologist and epidemiologist. After graduating from Baylor College of Medicine in 1996, Dr. Fullerton came to UCSF for her pediatrics residency and child neurology fellowship, and then joined the Child Neurology faculty in July 2002. She completed a vascular neurology fellowship between 2002 and 2003, and a two-year Masters in Clinical Research at UCSF in 2005. In 2001, she began collaborating with Dr. Johnston at UCSF using administrative data to describe the incidence and demographics of childhood stroke. She then obtained a grant from the American Heart Association to perform a population-based study of childhood stroke within Kaiser Permanente, a large managed care organization. This study led to NIH funding for another retrospective Kaiser study on the role of infection in the pathogenesis of childhood stroke. She is now the PI on an NIH-funded prospective 25-center international study entitled, The Vascular effects of Infection in Pediatric Stroke (VIPS). This study will determine the association between common infections and a focal cerebral arteriopathy that is commonly observed in previously healthy children presenting with an ischemic stroke. It will also provide data on recurrence rates after a first childhood stroke. Her long-term goal is to develop clinical trials for primary and secondary stroke prevention in children.
Bibliographic
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Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Franco S, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Huffman MD, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Magid D, Marcus GM, Marelli A, Matchar DB, McGuire DK, Mohler ER, Moy CS, Mussolino ME, Nichol G, Paynter NP, Schreiner PJ, Sorlie PD, Stein J, Turan TN, Virani SS, Wong ND, Woo D, Turner MB. Executive summary: heart disease and stroke statistics--2013 update: a report from the american heart association. Circulation. 2013 Jan 1; 127(1):143-52.
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Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Franco S, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Huffman MD, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Magid D, Marcus GM, Marelli A, Matchar DB, McGuire DK, Mohler ER, Moy CS, Mussolino ME, Nichol G, Paynter NP, Schreiner PJ, Sorlie PD, Stein J, Turan TN, Virani SS, Wong ND, Woo D, Turner MB. Heart disease and stroke statistics--2013 update: a report from the american heart association. Circulation. 2013 Jan 1; 127(1):e6-e245.
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Hills NK, Johnston SC, Sidney S, Zielinski BA, Fullerton HJ. Recent trauma and acute infection as risk factors for childhood arterial ischemic stroke. Ann Neurol. 2012 Dec; 72(6):850-8.
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Tangtiphaiboontana J, Hess CP, Bayer M, Drolet BA, Nassif LM, Metry DW, Barkovich AJ, Frieden IJ, Fullerton HJ. Neurodevelopmental Abnormalities in Children With PHACE Syndrome. J Child Neurol. 2013 May; 28(5):608-14.
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Hetts SW, Keenan K, Fullerton HJ, Young WL, English JD, Gupta N, Dowd CF, Higashida RT, Lawton MT, Halbach VV. Pediatric intracranial nongalenic pial arteriovenous fistulas: clinical features, angioarchitecture, and outcomes. AJNR Am J Neuroradiol. 2012 Oct; 33(9):1710-9.
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Fox CK, Johnston SC, Sidney S, Fullerton HJ. High critical care usage due to pediatric stroke: results of a population-based study. Neurology. 2012 Jul 31; 79(5):420-7.
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Siegel DH, Tefft KA, Kelly T, Johnson C, Metry D, Burrows P, Pope E, Cordisco M, Holland KE, Maheshwari M, Keith P, Garzon M, Hess C, Frieden IJ, Fullerton HJ, Drolet BA. Stroke in children with posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities (PHACE) syndrome: a systematic review of the literature. Stroke. 2012 Jun; 43(6):1672-4.
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Tatum J, Farid H, Cooke D, Fullerton H, Smith W, Higashida R, Halbach VV, Dowd C. Mechanical embolectomy for treatment of large vessel acute ischemic stroke in children. J Neurointerv Surg. 2013 Mar 1; 5(2):128-34.
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Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D, Turner MB. Executive summary: heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation. 2012 Jan 3; 125(1):188-97.
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Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D, Turner MB. Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation. 2012 Jan 3; 125(1):e2-e220.
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Bernard TJ, Manco-Johnson MJ, Lo W, MacKay MT, Ganesan V, DeVeber G, Goldenberg NA, Armstrong-Wells J, Dowling MM, Roach ES, Tripputi M, Fullerton HJ, Furie KL, Benseler SM, Jordan LC, Kirton A, Ichord R. Towards a consensus-based classification of childhood arterial ischemic stroke. Stroke. 2012 Feb; 43(2):371-7.
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Hills NK, Fullerton HJ. Atherosclerotic stroke in children? A public health red flag. Ann Neurol. 2011 Nov; 70(5):675-6.
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Dlamini N, Freeman JL, Mackay MT, Hawkins C, Shroff M, Fullerton HJ, Deveber GA. Intracranial dissection mimicking transient cerebral arteriopathy in childhood arterial ischemic stroke. J Child Neurol. 2011 Sep; 26(9):1203-6.
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Fullerton HJ, Elkind MS, Barkovich AJ, Glaser C, Glidden D, Hills NK, Leiva-Salinas C, Wintermark M, Deveber GA. The vascular effects of infection in Pediatric Stroke (VIPS) Study. J Child Neurol. 2011 Sep; 26(9):1101-10.
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Ichord RN, Bastian R, Abraham L, Askalan R, Benedict S, Bernard TJ, Beslow L, Deveber G, Dowling M, Friedman N, Fullerton H, Jordan L, Kan L, Kirton A, Amlie-Lefond C, Licht D, Lo W, McClure C, Pavlakis S, Smith SE, Tan M, Kasner S, Jawad AF. Interrater reliability of the Pediatric National Institutes of Health Stroke Scale (PedNIHSS) in a multicenter study. Stroke. 2011 Mar; 42(3):613-7.
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Roger VL, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, Carnethon MR, Dai S, de Simone G, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Greenlund KJ, Hailpern SM, Heit JA, Ho PM, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, McDermott MM, Meigs JB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Rosamond WD, Sorlie PD, Stafford RS, Turan TN, Turner MB, Wong ND, Wylie-Rosett J. Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation. 2011 Feb 1; 123(4):e18-e209.
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Kim AS, Fullerton HJ, Johnston SC. Risk of vascular events in emergency department patients discharged home with diagnosis of dizziness or vertigo. Ann Emerg Med. 2011 Jan; 57(1):34-41.
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Hess CP, Fullerton HJ, Metry DW, Drolet BA, Siegel DH, Auguste KI, Gupta N, Haggstrom AN, Dowd CF, Frieden IJ, Barkovich AJ. Cervical and intracranial arterial anomalies in 70 patients with PHACE syndrome. AJNR Am J Neuroradiol. 2010 Nov; 31(10):1980-6.
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Gelfand AA, Fullerton HJ, Goadsby PJ. Child neurology: Migraine with aura in children. Neurology. 2010 Aug 3; 75(5):e16-9.
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Fox CK, Fullerton HJ. Recent advances in childhood arterial ischemic stroke. Curr Atheroscler Rep. 2010 Jul; 12(4):217-24.
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Kenet G, Lütkhoff LK, Albisetti M, Bernard T, Bonduel M, Brandao L, Chabrier S, Chan A, deVeber G, Fiedler B, Fullerton HJ, Goldenberg NA, Grabowski E, Günther G, Heller C, Holzhauer S, Iorio A, Journeycake J, Junker R, Kirkham FJ, Kurnik K, Lynch JK, Male C, Manco-Johnson M, Mesters R, Monagle P, van Ommen CH, Raffini L, Rostásy K, Simioni P, Sträter RD, Young G, Nowak-Göttl U. Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of observational studies. Circulation. 2010 Apr 27; 121(16):1838-47.
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Amlie-Lefond C, Fullerton HJ. Rashes, sniffles, and stroke: a role for infection in ischemic stroke of childhood. Infect Disord Drug Targets. 2010 Apr; 10(2):67-75.
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Gardner MA, Hills NK, Sidney S, Johnston SC, Fullerton HJ. The 5-year direct medical cost of neonatal and childhood stroke in a population-based cohort. Neurology. 2010 Feb 2; 74(5):372-8.
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Waldron JS, Hetts SW, Armstrong-Wells J, Dowd CF, Fullerton HJ, Gupta N, Lawton MT. Multiple intracranial aneurysms and moyamoya disease associated with microcephalic osteodysplastic primordial dwarfism type II: surgical considerations. J Neurosurg Pediatr. 2009 Nov; 4(5):439-44.
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Potter CA, Armstrong-Wells J, Fullerton HJ, Young WL, Higashida RT, Dowd CF, Halbach VV, Hetts SW. Neonatal giant pial arteriovenous malformation: genesis or rapid enlargement in the third trimester. J Neurointerv Surg. 2009 Dec; 1(2):151-3.
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Goldenberg NA, Bernard TJ, Fullerton HJ, Gordon A, deVeber G. Antithrombotic treatments, outcomes, and prognostic factors in acute childhood-onset arterial ischaemic stroke: a multicentre, observational, cohort study. Lancet Neurol. 2009 Dec; 8(12):1120-7.
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Agrawal N, Johnston SC, Wu YW, Sidney S, Fullerton HJ. Imaging data reveal a higher pediatric stroke incidence than prior US estimates. Stroke. 2009 Nov; 40(11):3415-21.
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Amlie-Lefond C, deVeber G, Chan AK, Benedict S, Bernard T, Carpenter J, Dowling MM, Fullerton H, Hovinga C, Kirton A, Lo W, Zamel K, Ichord R. Use of alteplase in childhood arterial ischaemic stroke: a multicentre, observational, cohort study. Lancet Neurol. 2009 Jun; 8(6):530-6.
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Armstrong-Wells J, Grimes B, Sidney S, Kronish D, Shiboski SC, Adams RJ, Fullerton HJ. Utilization of TCD screening for primary stroke prevention in children with sickle cell disease. Neurology. 2009 Apr 14; 72(15):1316-21.
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Hetts SW, Narvid J, Sanai N, Lawton MT, Gupta N, Fullerton HJ, Dowd CF, Higashida RT, Halbach VV. Intracranial aneurysms in childhood: 27-year single-institution experience. AJNR Am J Neuroradiol. 2009 Aug; 30(7):1315-24.
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Amlie-Lefond C, Fullerton HJ. Thrombolytics for hyperacute stroke in children. Pediatr Hematol Oncol. 2009 Apr-May; 26(3):103-7.
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Amlie-Lefond C, Bernard TJ, Sébire G, Friedman NR, Heyer GL, Lerner NB, DeVeber G, Fullerton HJ. Predictors of cerebral arteriopathy in children with arterial ischemic stroke: results of the International Pediatric Stroke Study. Circulation. 2009 Mar 17; 119(10):1417-23.
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Armstrong-Wells J, Johnston SC, Wu YW, Sidney S, Fullerton HJ. Prevalence and predictors of perinatal hemorrhagic stroke: results from the kaiser pediatric stroke study. Pediatrics. 2009 Mar; 123(3):823-8.
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Jordan LC, Johnston SC, Wu YW, Sidney S, Fullerton HJ. The importance of cerebral aneurysms in childhood hemorrhagic stroke: a population-based study. Stroke. 2009 Feb; 40(2):400-5.
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Golomb MR, Fullerton HJ, Nowak-Gottl U, Deveber G. Male predominance in childhood ischemic stroke: findings from the international pediatric stroke study. Stroke. 2009 Jan; 40(1):52-7.
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Bernard TJ, Goldenberg NA, Armstrong-Wells J, Amlie-Lefond C, Fullerton HJ. Treatment of childhood arterial ischemic stroke. Ann Neurol. 2008 Jun; 63(6):679-96.
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Amlie-Lefond C, Sébire G, Fullerton HJ. Recent developments in childhood arterial ischaemic stroke. Lancet Neurol. 2008 May; 7(5):425-35.
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Sanai N, Fullerton H, Karl TR, Lawton MT. Aortocarotid bypass for hemispheric hypoperfusion in a child. J Neurosurg Pediatr. 2008 Apr; 1(4):343-7.
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Fullerton HJ, Wu YW, Sidney S, Johnston SC. Recurrent hemorrhagic stroke in children: a population-based cohort study. Stroke. 2007 Oct; 38(10):2658-62.
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Fullerton HJ. Thrombolytic therapy for ischemic stroke--suitable for children? Nat Clin Pract Neurol. 2007 Sep; 3(9):494-5.
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Fullerton HJ, Wu YW, Sidney S, Johnston SC. Risk of recurrent childhood arterial ischemic stroke in a population-based cohort: the importance of cerebrovascular imaging. Pediatrics. 2007 Mar; 119(3):495-501.
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Fullerton HJ, Gardner M, Adams RJ, Lo LC, Johnston SC. Obstacles to primary stroke prevention in children with sickle cell disease. Neurology. 2006 Sep 26; 67(6):1098-9.
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Wu YW, Lindan CE, Henning LH, Yoshida CK, Fullerton HJ, Ferriero DM, Barkovich AJ, Croen LA. Neuroimaging abnormalities in infants with congenital hemiparesis. Pediatr Neurol. 2006 Sep; 35(3):191-6.
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Sanchez-Mejia RO, Chennupati SK, Gupta N, Fullerton H, Young WL, Lawton MT. Superior outcomes in children compared with adults after microsurgical resection of brain arteriovenous malformations. J Neurosurg. 2006 Aug; 105(2 Suppl):82-7.
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Golomb MR, Fullerton HJ. Kinky vessels and double joints: useful clues for childhood stroke? Neurology. 2006 Jul 25; 67(2):199-200.
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Sofronas M, Ichord RN, Fullerton HJ, Lynch JK, Massicotte MP, Willan AR, deVeber G. Pediatric stroke initiatives and preliminary studies: What is known and what is needed? Pediatr Neurol. 2006 Jun; 34(6):439-45.
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Fullerton H, Lynch JK, deVeber G. The call for multicenter studies of pediatric stroke. Stroke. 2006 Feb; 37(2):330-1.
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Fullerton HJ. The emerging quandary of childhood stoke: better aim but no magic bullet. Stroke. 2006 Jan; 37(1):3.
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Fullerton HJ, Achrol AS, Johnston SC, McCulloch CE, Higashida RT, Lawton MT, Sidney S, Young WL. Long-term hemorrhage risk in children versus adults with brain arteriovenous malformations. Stroke. 2005 Oct; 36(10):2099-104.
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Chi JH, Fullerton HJ, Gupta N. Time trends and demographics of deaths from congenital hydrocephalus in children in the United States: National Center for Health Statistics data, 1979 to 1998. J Neurosurg. 2005 Aug; 103(2 Suppl):113-8.
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Lee J, Croen LA, Backstrand KH, Yoshida CK, Henning LH, Lindan C, Ferriero DM, Fullerton HJ, Barkovich AJ, Wu YW. Maternal and infant characteristics associated with perinatal arterial stroke in the infant. JAMA. 2005 Feb 9; 293(6):723-9.
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Wu YW, Backstrand KH, Zhao S, Fullerton HJ, Johnston SC. Declining diagnosis of birth asphyxia in California: 1991-2000. Pediatrics. 2004 Dec; 114(6):1584-90.
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Sébire G, Fullerton H, Riou E, deVeber G. Toward the definition of cerebral arteriopathies of childhood. Curr Opin Pediatr. 2004 Dec; 16(6):617-22.
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Fullerton HJ, Elkins JS, Johnston SC. Pediatric Stroke Belt: geographic variation in stroke mortality in US children. Stroke. 2004 Jul; 35(7):1570-3.
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Bautista J, Fullerton H, Briseno M, Cui H, Fass R. The effect of an empirical trial of high-dose lansoprazole on symptom response of patients with non-cardiac chest pain--a randomized, double-blind, placebo-controlled, crossover trial. Aliment Pharmacol Ther. 2004 May 15; 19(10):1123-30.
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Fullerton HJ, Adams RJ, Zhao S, Johnston SC. Declining stroke rates in Californian children with sickle cell disease. Blood. 2004 Jul 15; 104(2):336-9.
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Fullerton HJ, Von Scheven E. Back to school on APS: rethinking the risk of recurrent stroke in children. Neurology. 2004 Jan 27; 62(2):172-3.
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Fullerton HJ, Aminoff AR, Ferriero DM, Gupta N, Dowd CF. Neurodevelopmental outcome after endovascular treatment of vein of Galen malformations. Neurology. 2003 Nov 25; 61(10):1386-90.
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Fullerton HJ, Wu YW, Zhao S, Johnston SC. Risk of stroke in children: ethnic and gender disparities. Neurology. 2003 Jul 22; 61(2):189-94.
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Fullerton HJ, Chetkovich DM, Wu YW, Smith WS, Johnston SC. Deaths from stroke in US children, 1979 to 1998. Neurology. 2002 Jul 9; 59(1):34-9.
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Fullerton HJ, Johnston SC, Smith WS. Arterial dissection and stroke in children. Neurology. 2001 Oct 9; 57(7):1155-60.
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Fullerton HJ, Ditelberg JS, Chen SF, Sarco DP, Chan PH, Epstein CJ, Ferriero DM. Copper/zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia. Ann Neurol. 1998 Sep; 44(3):357-64.
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Fullerton GD, Cameron IL, Hunter K, Fullerton HJ. Proton magnetic resonance relaxation behavior of whole muscle with fatty inclusions. Radiology. 1985 Jun; 155(3):727-30.
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