Mingliang Jin, PhD

Title(s)Specialist, Biochemistry and Biophysics
SchoolSchool of Medicine
Address35 Medical Center Way, #3300
San Francisco CA 94143
Phone415-514-9708
PronounsHe/Him/His
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    SIBCB, ShanghaiPhD05/2019

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Discovery of Diphenyl Ether Derivatives as Novel BKCa Channel Activators: Structure-Activity Relationship, Cryo-EM Complex Structures, and In Vivo Animal Studies. J Med Chem. 2025 Feb 27; 68(4):4259-4286. Park SB, Lee NY, Lee EY, Kim S, Lee N, Roh EC, Kim YG, Kim HJ, Jin MS, Park CS, Kim YC. PMID: 39947888.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Discovery of Diphenyl Ether Derivatives as Novel BKCa Channel Activators: Structure-Activity Relationship, Cryo-EM Complex Structures, and In Vivo Animal Studies. J Med Chem. 2025 Feb 27; 68(4):4259-4286. Park SB, Lee NY, Lee EY, Kim S, Lee N, Roh EC, Kim YG, Kim HJ, Jin MS, Park CS, Kim YC. PMID: 39947888.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Cryo-EM structures reveal the H+/citrate symport mechanism of Drosophila INDY. Life Sci Alliance. 2025 Apr; 8(4). Kim S, Park JG, Choi SH, Kim JW, Jin MS. PMID: 39884835; PMCID: PMC11782487.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. Latent-TGF-β has a domain swapped architecture. Res Sq. 2024 Nov 01. Nishimura S, Jin M, Seed R, Shing T, Cheng Y. PMID: 39574885; PMCID: PMC11581116.
      View in: PubMed   Mentions:
    5. Dynamic allostery drives autocrine and paracrine TGF-β signaling. Cell. 2024 Oct 31; 187(22):6200-6219.e23. Jin M, Seed RI, Cai G, Shing T, Wang L, Ito S, Cormier A, Wankowicz SA, Jespersen JM, Baron JL, Carey ND, Campbell MG, Yu Z, Tang PK, Cossio P, Wen W, Lou J, Marks J, Nishimura SL, Cheng Y. PMID: 39288764; PMCID: PMC11531391.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    6. Cryo-EM structure of the human glucose transporter GLUT7. Biochem Biophys Res Commun. 2024 12 17; 738:150544. Lee SS, Kim S, Jin MS. PMID: 39163817.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. J Biol Chem. 2022 09; 298(9):102288. Yu Z, Chen J, Takagi E, Wang F, Saha B, Liu X, Joubert LM, Gleason CE, Jin M, Li C, Nowotny C, Agard D, Cheng Y, Pearce D. PMID: 35926713; PMCID: PMC9440446.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    8. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. Res Sq. 2021 May 19. Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, Li F, Li Y, Nguyen HC, Nowotny C, Owens TW, Peters JK, Rizo AN, Schulze-Gahmen U, Smith AM, Young ID, Yu Z, Asarnow D, Billesbølle C, Campbell MG, Chen J, Chen KH, Chio US, Dickinson MS, Doan L, Jin M, Kim K, Li J, Li YL, Linossi E, Liu Y, Lo M, Lopez J, Lopez KE, Mancino A, Moss FR, Paul MD, Pawar KI, Pelin A, Pospiech TH, Puchades C, Remesh SG, Safari M, Schaefer K, Sun M, Tabios MC, Thwin AC, Titus EW, Trenker R, Tse E, Tsui TKM, Wang F, Zhang K, Zhang Y, Zhao J, Zhou F, Zhou Y, Zuliani-Alvarez L, QCRG Structural Biology Consortium, Agard DA, Cheng Y, Fraser JS, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Swaney DL, Krogan NJ, Frost A, Rosenberg OS, Verba KA. PMID: 34031651; PMCID: PMC8142659.
      View in: PubMed   Mentions: 2  
    9. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. bioRxiv. 2021 May 11. Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, Li F, Li Y, Nguyen HC, Nowotny C, Owens TW, Peters JK, Rizo AN, Schulze-Gahmen U, Smith AM, Young ID, Yu Z, Asarnow D, Billesbølle C, Campbell MG, Chen J, Chen KH, Chio US, Dickinson MS, Doan L, Jin M, Kim K, Li J, Li YL, Linossi E, Liu Y, Lo M, Lopez J, Lopez KE, Mancino A, Moss FR, Paul MD, Pawar KI, Pelin A, Pospiech TH, Puchades C, Remesh SG, Safari M, Schaefer K, Sun M, Tabios MC, Thwin AC, Titus EW, Trenker R, Tse E, Tsui TKM, Wang F, Zhang K, Zhang Y, Zhao J, Zhou F, Zhou Y, Zuliani-Alvarez L, QCRG Structural Biology Consortium, Agard DA, Cheng Y, Fraser JS, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Swaney DL, Krogan NJ, Frost A, Rosenberg OS, Verba KA. PMID: 34013269; PMCID: PMC8132225.
      View in: PubMed   Mentions: 4  
    10. An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science. 2020 12 18; 370(6523):1473-1479. Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. PMID: 33154106; PMCID: PMC7857409.
      View in: PubMed   Mentions: 239     Fields:    Translation:HumansAnimalsCells
    11. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation. bioRxiv. 2020 Aug 17. Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. PMID: 32817938; PMCID: PMC7430568.
      View in: PubMed   Mentions: 6  
    12. A complex structure of arrestin-2 bound to a G protein-coupled receptor. Cell Res. 2019 Dec; 29(12):971-983. Yin W, Li Z, Jin M, Yin YL, de Waal PW, Pal K, Yin Y, Gao X, He Y, Gao J, Wang X, Zhang Y, Zhou H, Melcher K, Jiang Y, Cong Y, Edward Zhou X, Yu X, Eric Xu H. PMID: 31776446; PMCID: PMC6951264.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansCells
    13. An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity. Proc Natl Acad Sci U S A. 2019 09 24; 116(39):19513-19522. Jin M, Han W, Liu C, Zang Y, Li J, Wang F, Wang Y, Cong Y. PMID: 31492816; PMCID: PMC6765261.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    14. TRiC/CCT Chaperonin: Structure and Function. Subcell Biochem. 2019; 93:625-654. Jin M, Liu C, Han W, Cong Y. PMID: 31939165.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    15. Development of a yeast internal-subunit eGFP labeling strategy and its application in subunit identification in eukaryotic group II chaperonin TRiC/CCT. Sci Rep. 2018 02 05; 8(1):2374. Zang Y, Wang H, Cui Z, Jin M, Liu C, Han W, Wang Y, Cong Y. PMID: 29403048; PMCID: PMC5799240.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    16. Structural insights into the oligomerization of FtsH periplasmic domain from Thermotoga maritima. Biochem Biophys Res Commun. 2018 01 01; 495(1):1201-1207. An JY, Sharif H, Kang GB, Park KJ, Lee JG, Lee S, Jin MS, Song JJ, Wang J, Eom SH. PMID: 29180014.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    17. Identification of an allosteric network that influences assembly and function of group II chaperonins. Nat Struct Mol Biol. 2017 09 07; 24(9):683-684. Jin M, Cong Y. PMID: 28880864.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    18. Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5. Genes Dev. 2016 11 01; 30(21):2391-2403. Jin W, Wang Y, Liu CP, Yang N, Jin M, Cong Y, Wang M, Xu RM. PMID: 27881601; PMCID: PMC5131779.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    19. Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM. Nat Struct Mol Biol. 2016 Dec; 23(12):1083-1091. Zang Y, Jin M, Wang H, Cui Z, Kong L, Liu C, Cong Y. PMID: 27775711.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    20. Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell. 2007 Sep 21; 130(6):1071-82. Jin MS, Kim SE, Heo JY, Lee ME, Kim HM, Paik SG, Lee H, Lee JO. PMID: 17889651.
      View in: PubMed   Mentions: 599     Fields:    Translation:HumansAnimalsCells
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