David Bulkley, PhD
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Title(s) | RESEARCHER, Biochemistry and Biophysics |
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School | School of Medicine |
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Address | Location Required Varies CA 00000
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Phone | 415-514-9708 |
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vCard | Download vCard |
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Research Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.)
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An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science. 2020 12 18; 370(6523):1473-1479.
Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, Walter P, Manglik A. PMID: 33154106.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimalsCells
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Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit. Proc Natl Acad Sci U S A. 2020 Nov 17; 117(46):28838-28846.
Zhang Y, Lu WJ, Bulkley DP, Liang J, Ralko A, Han S, Roberts KJ, Li A, Cho W, Cheng Y, Manglik A, Beachy PA. PMID: 33139559.
View in: PubMed Mentions: Fields:
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Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization. bioRxiv. 2020 Jul 15.
Wang B, Asarnow D, Lee WH, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Hu Y, Seah SGK, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI. PMID: 32699850.
View in: PubMed Mentions:
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Ion transport and regulation in a synaptic vesicle glutamate transporter. Science. 2020 05 22; 368(6493):893-897.
Li F, Eriksen J, Finer-Moore J, Chang R, Nguyen P, Bowen A, Myasnikov A, Yu Z, Bulkley D, Cheng Y, Edwards RH, Stroud RM. PMID: 32439795.
View in: PubMed Mentions: 1 Fields: Translation: AnimalsCells
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Abstract OR-16: High Resolution Cryo-Electron Microscopy and New Direct Electron Detector from Gatan - K3. International Journal of Biomedicine. 2019 Jun 30; 9(Suppl_1):s12-s12.
Alexander Myasnikov, Shawn Zheng, David Bulkley, Yifan Cheng, David Agard. .
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Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched. Cell. 2018 11 15; 175(5):1352-1364.e14.
Zhang Y, Bulkley DP, Xin Y, Roberts KJ, Asarnow DE, Sharma A, Myers BR, Cho W, Cheng Y, Beachy PA. PMID: 30415841.
View in: PubMed Mentions: 24 Fields: Translation: HumansAnimalsCells
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K3 - A First Look at The New Direct Electron Detection Camera from Gatan Company. Microscopy and Microanalysis. 2018 Aug 1; 24(S1):890-891.
Alexander Myasnikov, Shawn Zheng, David Bulkley, Yifan Cheng, David Agard. .
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A simple and robust procedure for preparing graphene-oxide cryo-EM grids. J Struct Biol. 2018 10; 204(1):80-84.
Palovcak E, Wang F, Zheng SQ, Yu Z, Li S, Betegon M, Bulkley D, Agard DA, Cheng Y. PMID: 30017701.
View in: PubMed Mentions: 13 Fields:
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Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nat Commun. 2018 06 13; 9(1):2302.
Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkley D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ. PMID: 29899465.
View in: PubMed Mentions: 17 Fields: Translation: HumansAnimalsCells
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Graphene-Oxide Substrate for High-Resolution Single Particle Cryo-EM. Biophysical Journal. 2018 Feb 1; 114(3):11a.
Eugene Palovcak, David Bulkley, Shawn Zheng, Feng Wang, David Agard, Yifan Cheng. .
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Cryo-EM structure of the Mechanotransduction Channel NOMPC. Biophysical Journal. 2018 Feb 1; 114(3):22a.
Peng Jin, David Bulkley, Yanmeng Guo, Wei Zhang, Zhenhao Guo, Walter Huynh, Shenping Wu, Shan Meltzer, Tong Cheng, Lily Yeh Jan, Yuh-Nung Jan, Yifan Cheng. .
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Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature. 2017 12 21; 552(7685):426-429.
Dang S, Feng S, Tien J, Peters CJ, Bulkley D, Lolicato M, Zhao J, Zuberbühler K, Ye W, Qi L, Chen T, Craik CS, Jan YN, Minor DL, Cheng Y, Jan LY. PMID: 29236684.
View in: PubMed Mentions: 51 Fields: Translation: HumansAnimalsCells
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Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature. 2017 07 06; 547(7661):118-122.
Jin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Cheng T, Jan LY, Jan YN, Cheng Y. PMID: 28658211.
View in: PubMed Mentions: 51 Fields: Translation: AnimalsCells
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The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs. Cell. 2016 Oct 20; 167(3):763-773.e11.
Shen PS, Yang X, DeCaen PG, Liu X, Bulkley D, Clapham DE, Cao E. PMID: 27768895.
View in: PubMed Mentions: 71 Fields: Translation: HumansAnimalsCells
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Conformational changes of elongation factor G on the ribosome during tRNA translocation. Cell. 2015 Jan 15; 160(1-2):219-27.
Lin J, Gagnon MG, Bulkley D, Steitz TA. PMID: 25594181.
View in: PubMed Mentions: 46 Fields: Translation: Cells
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Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Mol Cell. 2014 Nov 20; 56(4):531-40.
Polikanov YS, Osterman IA, Szal T, Tashlitsky VN, Serebryakova MV, Kusochek P, Bulkley D, Malanicheva IA, Efimenko TA, Efremenkova OV, Konevega AL, Shaw KJ, Bogdanov AA, Rodnina MV, Dontsova OA, Mankin AS, Steitz TA, Sergiev PV. PMID: 25306919.
View in: PubMed Mentions: 25 Fields: Translation: Cells
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Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome. Science. 2014 Aug 08; 345(6197):684-7.
Gagnon MG, Lin J, Bulkley D, Steitz TA. PMID: 25104389.
View in: PubMed Mentions: 23 Fields: Translation: Cells
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Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome. Science. 2012 Mar 16; 335(6074):1370-2.
Gagnon MG, Seetharaman SV, Bulkley D, Steitz TA. PMID: 22422986.
View in: PubMed Mentions: 43 Fields: Translation: Cells
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Structural Studies of the Functional Complexes of the 50S and 70S Ribosome, a Major Antibiotic Target. Macromolecular Crystallography. 2012 Jan 1; 135-148.
Thomas A. Steitz, Gregor Blaha, C. Axel Innis, Robin Evans Stanley, David Bulkley. .
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Structural studies of complexes of the 70S ribosome. Ribosomes. 2011 Jan 1; 31-43.
C. Axel Innis, Gregor Blaha, David Bulkley, Thomas A. Steitz. .
View in: Publisher Site Mentions:
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Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc Natl Acad Sci U S A. 2010 Oct 05; 107(40):17158-63.
Bulkley D, Innis CA, Blaha G, Steitz TA. PMID: 20876130.
View in: PubMed Mentions: 78 Fields: Translation: Cells
This graph shows the total number of publications by year. To see the data as text, click here.
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Year | Publications |
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2010 | 1 | 2011 | 1 | 2012 | 2 | 2014 | 2 | 2015 | 1 | 2016 | 1 | 2017 | 2 | 2018 | 6 | 2019 | 1 | 2020 | 4 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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