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Hobart Harris, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentSurgery
Address513 Parnassus Ave, Med Sci
San Francisco CA 94117
Phone415-514-3891
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine - Surgery
    Harvard UniversityM.D.1983School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Complex Ventral Hernia Repair
    NIH/NIDDK R21DK093006Jul 15, 2013 - Jun 30, 2016
    Role: Principal Investigator
    Lipoproteins and Microbial Immunity
    NIH/NIGMS R01GM095967Aug 15, 2010 - Jul 31, 2014
    Role: Principal Investigator
    Lipoproteins Modulate the Hepatic Response to Endotoxin
    NIH/NIGMS R01GM057463May 1, 1999 - Jan 31, 2010
    Role: Principal Investigator
    CHYLOMICRON REMNANTS &ATHEROSCLEROSIS
    NIH/NHLBI F32HL007737Nov 5, 1988
    Role: Principal Investigator
    Research Training in Gastrointestinal Surgery
    NIH/NIDDK T32DK007573Jul 1, 1988 - Jun 30, 2020
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Clinical Trials
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Urisman T, Garcia A, Harris H. Impact of surgical intensive care unit interdisciplinary rounds on interprofessional collaboration and quality of care: Mixed qualitative-quantitative study. Intensive Crit Care Nurs. 2017 Aug 30. PMID: 28865984.
      View in: PubMed
    2. Kim SS, Nakakura EK, Wang ZJ, Kim GE, Corvera CU, Harris H, Kirkwood KS, Hirose R, Tempero MA, Ko AH. Preoperative FOLFIRINOX for borderline resectable pancreatic cancer: Is radiation necessary in the modern era of chemotherapy? J Surg Oncol. 2016 Oct; 114(5):587-596. PMID: 27444658.
      View in: PubMed
    3. Wong A, Lee S, Nathan NS, Wang F, Hansen SL, Harris H, Sbitany H. Postoperative Prophylactic Antibiotic Use following Ventral Hernia Repair with Placement of Surgical Drains Reduces the Postoperative Surgical-Site Infection Rate. Plast Reconstr Surg. 2016 Jan; 137(1):285-94. PMID: 26371392.
      View in: PubMed
    4. Wong A, Lee S, Nathan NS, Wang F, Hansen SL, Harris H, Sbitany H. Postoperative Prophylactic Antibiotic Use Following Ventral Hernia Repair with Placement of Surgical Drains Reduces Postoperative Surgical Site Infection Rate. Plast Reconstr Surg. 2015 Oct; 136(4 Suppl):12-3. PMID: 26397498.
      View in: PubMed
    5. Liao A, Harris H, Maharbiz MM. Towards a full-field strain sensor for guiding hernia repairs. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug; 2015:1243-6. PMID: 26736492.
      View in: PubMed
    6. Bettini A, Ulloa JG, Harris H. Appendicitis within Morgagni Hernia and simultaneous Paraesophageal Hernia. BMC Surg. 2015 Feb 02; 15:15. PMID: 25644716; PMCID: PMC4417238.
    7. Brown I, Bellevue O, Shawo A, Woldesemayat H, Lyo V, Rayikanti B, Lee M, Uzosike ED, Kasravi S, Harris H. Low-dose cyclophosphamide improves survival in a murine treatment model of sepsis. Shock. 2015 Jan; 43(1):92-8. PMID: 25243421; PMCID: PMC4269572.
    8. Carter JT, Kaplan JA, Nguyen JN, Lin MY, Rogers SJ, Harris H. A prospective, randomized controlled trial of single-incision laparoscopic vs conventional 3-port laparoscopic appendectomy for treatment of acute appendicitis. J Am Coll Surg. 2014 May; 218(5):950-9. PMID: 24684867.
      View in: PubMed
    9. Sanchez Rodriguez R, Pauli ML, Neuhaus IM, Yu SS, Arron ST, Harris H, Yang SH, Anthony BA, Sverdrup FM, Krow-Lucal E, MacKenzie TC, Johnson DS, Meyer EH, Löhr A, Hsu A, Koo J, Liao W, Gupta R, Debbaneh MG, Butler D, Huynh M, Levin EC, Leon A, Hoffman WY, McGrath MH, Alvarado MD, Ludwig CH, Truong HA, Maurano MM, Gratz IK, Abbas AK, Rosenblum MD. Memory regulatory T cells reside in human skin. J Clin Invest. 2014 Mar; 124(3):1027-36. PMID: 24509084; PMCID: PMC3934172.
    10. Beard JH, Oresanya LB, Akoko L, Mwanga A, Dicker RA, Harris H. An estimation of inguinal hernia epidemiology adjusted for population age structure in Tanzania. Hernia. 2014 Apr; 18(2):289-95. PMID: 24241326.
      View in: PubMed
    11. Harris H. Clinical outcomes of biologic mesh: where do we stand? Surg Clin North Am. 2013 Oct; 93(5):1217-25. PMID: 24035084.
      View in: PubMed
    12. Harris H. Biologic mesh for ventral hernia repair: a cautionary tale. Ann Surg. 2013 Jun; 257(6):997-8. PMID: 23629526.
      View in: PubMed
    13. Beard JH, Oresanya LB, Ohene-Yeboah M, Dicker RA, Harris H. Characterizing the global burden of surgical disease: a method to estimate inguinal hernia epidemiology in Ghana. World J Surg. 2013 Mar; 37(3):498-503. PMID: 23224074.
      View in: PubMed
    14. Primus FE, Harris H. A critical review of biologic mesh use in ventral hernia repairs under contaminated conditions. Hernia. 2013 Feb; 17(1):21-30. PMID: 23296600; PMCID: PMC3601571.
    15. Chuang KI, Corley D, Postlethwaite DA, Merchant M, Harris H. Does increased experience with laparoscopic cholecystectomy yield more complex bile duct injuries? Am J Surg. 2012 Apr; 203(4):480-7. PMID: 22326050.
      View in: PubMed
    16. Chuang KI, Leung B, Hsu N, Harris H. Heparin protects against septic mortality via apoE-antagonism. Am J Surg. 2011 Sep; 202(3):325-35. PMID: 21741028; PMCID: PMC3163763.
    17. Leung B, Harris H. NKT cells: the culprits of sepsis? J Surg Res. 2011 May 01; 167(1):87-95. PMID: 21035139.
      View in: PubMed
    18. Leung B, Harris H. NKT cells in sepsis. Clin Dev Immunol. 2010; 2010. PMID: 20953368; PMCID: PMC2952903.
    19. Spitzer AL, Chuang KI, Victorino GP, Kasravi B, Curran B, Lee D, Harris H. Chylomicrons combined with endotoxin moderate microvascular permeability. Innate Immun. 2011 Feb; 17(3):283-92. PMID: 20423922.
      View in: PubMed
    20. Chuang K, Elford EL, Tseng J, Leung B, Harris H. An expanding role for apolipoprotein E in sepsis and inflammation. Am J Surg. 2010 Sep; 200(3):391-7. PMID: 20409531; PMCID: PMC2909338.
    21. Rogers SJ, Cello JP, Horn JK, Siperstein AE, Schecter WP, Campbell AR, Mackersie RC, Rodas A, Kreuwel HT, Harris H. Prospective randomized trial of LC+LCBDE vs ERCP/S+LC for common bile duct stone disease. Arch Surg. 2010 Jan; 145(1):28-33. PMID: 20083751.
      View in: PubMed
    22. Mohebali K, Young DM, Hansen SL, Shawo A, Freise CE, Chang DS, Maa J, Harris H. Open incisional hernia repair at an academic tertiary care medical center. Arch Surg. 2009 Sep; 144(9):848-52. PMID: 19797110.
      View in: PubMed
    23. Schecter WP, Hirshberg A, Chang DS, Harris H, Napolitano LM, Wexner SD, Dudrick SJ. Enteric fistulas: principles of management. J Am Coll Surg. 2009 Oct; 209(4):484-91. PMID: 19801322.
      View in: PubMed
    24. Jamshidi R, Hill A, Harris H. Anaphylaxis caused by recurrent hydatid disease. Surg Infect (Larchmt). 2009 Apr; 10(2):155-7. PMID: 18687050.
      View in: PubMed
    25. Mukhtar RA, Kattan OM, Harris H. Variation in annual volume at a university hospital does not predict mortality for pancreatic resections. HPB Surg. 2008; 2008:190914. PMID: 19259261; PMCID: PMC2648113.
    26. Jancelewicz T, Vu LT, Shawo AE, Yeh B, Gasper WJ, Harris H. Predicting strangulated small bowel obstruction: an old problem revisited. J Gastrointest Surg. 2009 Jan; 13(1):93-9. PMID: 18685902.
      View in: PubMed
    27. Kattan OM, Kasravi FB, Elford EL, Schell MT, Harris H. Apolipoprotein E-mediated immune regulation in sepsis. J Immunol. 2008 Jul 15; 181(2):1399-408. PMID: 18606694.
      View in: PubMed
    28. Maa J, Wachter RM, Gosnell JE, Harris H. The future of general surgery. JAMA. 2008 Mar 05; 299(9):1015; author reply 1015-6. PMID: 18319410.
      View in: PubMed
    29. Somsouk M, Shergill AK, Grenert JP, Harris H, Cello JP, Shah JN. Actinomycosis mimicking a pancreatic head neoplasm diagnosed by EUS-guided FNA. Gastrointest Endosc. 2008 Jul; 68(1):186-7. PMID: 18291393.
      View in: PubMed
    30. Jamshidi R, Harris H, Campbell AR. The value of teaching anatomy to medical students. Bull Am Coll Surg. 2008 Mar; 93(3):36. PMID: 18390228.
      View in: PubMed
    31. Schell MT, Barcia A, Spitzer AL, Harris H. Pancreaticoduodenectomy: volume is not associated with outcome within an academic health care system. HPB Surg. 2008; 2008:825940. PMID: 18475317; PMCID: PMC2246060.
    32. Maa J, Gosnell JE, Carter JT, Wachter RM, Harris H. The surgical hospitalist: a new solution for emergency surgical care? Bull Am Coll Surg. 2007 Nov; 92(11):8-17. PMID: 18041231.
      View in: PubMed
    33. Rajendran PM, Young D, Maurer T, Chambers H, Perdreau-Remington F, Ro P, Harris H. Randomized, double-blind, placebo-controlled trial of cephalexin for treatment of uncomplicated skin abscesses in a population at risk for community-acquired methicillin-resistant Staphylococcus aureus infection. Antimicrob Agents Chemother. 2007 Nov; 51(11):4044-8. PMID: 17846141; PMCID: PMC2151464.
    34. Kasravi B, Lee DH, Lee JW, Dada S, Harris H. Chylomicron-bound LPS selectively inhibits the hepatocellular response to proinflammatory cytokines. J Surg Res. 2008 May 01; 146(1):96-103. PMID: 17707407; PMCID: PMC2829601.
    35. Maa J, Carter JT, Gosnell JE, Wachter R, Harris H. The surgical hospitalist: a new model for emergency surgical care. J Am Coll Surg. 2007 Nov; 205(5):704-11. PMID: 17964447.
      View in: PubMed
    36. Derish PA, Maa J, Ascher NL, Harris H. Enhancing the mission of academic surgery by promoting scientific writing skills. J Surg Res. 2007 Jun 15; 140(2):177-83. PMID: 17509262.
      View in: PubMed
    37. Rajendran PM, Young DM, Maurer T, Chambers HF, Jacobson MA, Harris H. Antibiotic use in the treatment of soft tissue abscesses: a survey of current practice. Surg Infect (Larchmt). 2007 Apr; 8(2):237-8. PMID: 17437370.
      View in: PubMed
    38. Maa J, Gosnell JE, Gibbs VC, Harris H. Exporting excellence for Whipple resection to refine the Leapfrog Initiative. J Surg Res. 2007 Apr; 138(2):189-97. PMID: 17292411.
      View in: PubMed
    39. Paydar KZ, Hansen SL, Charlebois ED, Harris H, Young DM. Inappropriate antibiotic use in soft tissue infections. Arch Surg. 2006 Sep; 141(9):850-4; discussion 855-6. PMID: 16983028.
      View in: PubMed
    40. Spitzer AL, Barcia AM, Schell MT, Barber A, Norman J, Grendell J, Harris H. Applying Ockham's razor to pancreatitis prognostication: a four-variable predictive model. Ann Surg. 2006 Mar; 243(3):380-8. PMID: 16495704; PMCID: PMC1448950.
    41. Spitzer AL, Harris H. Statins attenuate sepsis. Surgery. 2006 Mar; 139(3):283-7. PMID: 16546490.
      View in: PubMed
    42. Barcia AM, Harris H. Triglyceride-rich lipoproteins as agents of innate immunity. Clin Infect Dis. 2005 Nov 15; 41 Suppl 7:S498-503. PMID: 16237653.
      View in: PubMed
    43. Harris H. Apolipoprotein E: from Alzheimer's to sepsis. Crit Care Med. 2005 Nov; 33(11):2696-7. PMID: 16276207.
      View in: PubMed
    44. Spitzer AL, Mukhtar RA, Harris H. Image of the month--quiz case. Traumatic intramuscular cyst of the duodenum. Arch Surg. 2005 Oct; 140(10):1005-6. PMID: 16230553.
      View in: PubMed
    45. Harris H, Davis BR, Vitale GC. Cholecystectomy after endoscopic sphincterotomy for common bile duct stones: is surgery necessary? Surg Innov. 2005 Sep; 12(3):187-94. PMID: 16224638.
      View in: PubMed
    46. Spitzer AL, Thoeni RF, Barcia AM, Schell MT, Harris H. Early nonenhanced abdominal computed tomography can predict mortality in severe acute pancreatitis. J Gastrointest Surg. 2005 Sep-Oct; 9(7):928-33. PMID: 16137586.
      View in: PubMed
    47. Schell MT, Spitzer AL, Johnson JA, Lee D, Harris H. Heat shock inhibits NF-kB activation in a dose- and time-dependent manner. J Surg Res. 2005 Nov; 129(1):90-3. PMID: 16139305.
      View in: PubMed
    48. Harris H. Lipoproteins are protective beyond high-density lipoprotein cholesterol and heart disease. Crit Care Med. 2005 Aug; 33(8):1859-60. PMID: 16096467.
      View in: PubMed
    49. Davis BR, Harris H, Vitale GC. The evolution of endoscopy: wireless capsule cameras for the diagnosis of occult gastrointestinal bleeding and inflammatory bowel disease. Surg Innov. 2005 Jun; 12(2):129-33. PMID: 16034501.
      View in: PubMed
    50. Kasravi FB, Lee DH, Weisgraber K, Harris H. Lipoprotein-bound endotoxin exerts an immunomodulatory effect on hepatocytes through the lipid A domain of LPS. J Endotoxin Res. 2005; 11(1):19-24. PMID: 15826374.
      View in: PubMed
    51. Young DM, Harris H, Charlebois ED, Chambers H, Campbell A, Perdreau-Remington F, Lee C, Mankani M, Mackersie R, Schecter WP. An epidemic of methicillin-resistant Staphylococcus aureus soft tissue infections among medically underserved patients. Arch Surg. 2004 Sep; 139(9):947-51; discussion 951-3. PMID: 15381611.
      View in: PubMed
    52. Harris H, Barcia A, Schell MT, Thoeni RF, Schecter WP. Necrotizing pancreatitis: a surgical approach independent of documented infection. HPB (Oxford). 2004; 6(3):161-8. PMID: 18333070; PMCID: PMC2020671.
    53. Kasravi FB, Brecht WJ, Weisgraber KH, Harris H. Induction of cytokine tolerance requires internalization of Chylomicron-Bound LPS into hepatocytes. J Surg Res. 2003 Dec; 115(2):303-9. PMID: 14697298.
      View in: PubMed
    54. Miller G, Schecter WP, Harris H. Gallbladder ascariasis in a patient with severe pancreatitis. Surgery. 2003 Apr; 133(4):445-6. PMID: 12717365.
      View in: PubMed
    55. Kasravi FB, Welch WJ, Peters-Lideu CA, Weisgraber KH, Harris H. Induction of cytokine tolerance in rodent hepatocytes by chylomicron-bound LPS is low-density lipoprotein receptor dependent. Shock. 2003 Feb; 19(2):157-62. PMID: 12578125.
      View in: PubMed
    56. Harris H, Kasravi FB. Lipoprotein-bound LPS induces cytokine tolerance in hepatocytes. J Endotoxin Res. 2003; 9(1):45-50. PMID: 12691618.
      View in: PubMed
    57. Harris H, Young DM. Care of injection drug users with soft tissue infections in San Francisco, California. Arch Surg. 2002 Nov; 137(11):1217-22. PMID: 12413304.
      View in: PubMed
    58. Kumwenda ZL, Wong CB, Johnson JA, Gosnell JE, Welch WJ, Harris H. Chylomicron-bound endotoxin selectively inhibits NF-kappaB activation in rat hepatocytes. Shock. 2002 Aug; 18(2):182-8. PMID: 12166784.
      View in: PubMed
    59. Harris H, Brady SE, Rapp JH. Hepatic endosomal trafficking of lipoprotein-bound endotoxin in rats. J Surg Res. 2002 Jul; 106(1):188-95. PMID: 12127825.
      View in: PubMed
    60. Harris H, Johnson JA, Wigmore SJ. Endogenous lipoproteins impact the response to endotoxin in humans. Crit Care Med. 2002 Jan; 30(1):23-31. PMID: 11902267.
      View in: PubMed
    61. Gosnell FE, O'Neill BB, Harris H. Necrotizing pancreatitis during pregnancy: a rare cause and review of the literature. J Gastrointest Surg. 2001 Jul-Aug; 5(4):371-6. PMID: 11985977.
      View in: PubMed
    62. O'Neill BB, Gosnell JE, Lull RJ, Schecter WP, Koch J, Halvorsen RA, Harris H. Cinematic nuclear scintigraphy reliably directs surgical intervention for patients with gastrointestinal bleeding. Arch Surg. 2000 Sep; 135(9):1076-81; discussion 1081-2. PMID: 10982513.
      View in: PubMed
    63. Gosnell JE, Wong CB, Kumwenda ZL, Welch WJ, Harris H. Extracellular matrix regulates the hepatocellular heat shock response. J Surg Res. 2000 Jun 01; 91(1):43-9. PMID: 10816348.
      View in: PubMed
    64. Harris H, Gosnell JE, Kumwenda ZL. The lipemia of sepsis: triglyceride-rich lipoproteins as agents of innate immunity. J Endotoxin Res. 2000; 6(6):421-30. PMID: 11521066.
      View in: PubMed
    65. Harris H, Morabito DJ, Mackersie RC, Halvorsen RA, Schecter WP. Leukocytosis and free fluid are important indicators of isolated intestinal injury after blunt trauma. J Trauma. 1999 Apr; 46(4):656-9. PMID: 10217230.
      View in: PubMed
    66. Harris H, Rockey DC, Young DM, Welch WJ. Diet-induced protection against lipopolysaccharide includes increased hepatic NO production. J Surg Res. 1999 Apr; 82(2):339-45. PMID: 10090849.
      View in: PubMed
    67. Sheen-Chen SM, Chau P, Harris H. Obstructive jaundice alters Kupffer cell function independent of bacterial translocation. J Surg Res. 1998 Dec; 80(2):205-9. PMID: 9878315.
      View in: PubMed
    68. Harris H, Kumwenda ZL, Sheen-Chen SM, Shah A, Schecter WP. Recurrent pyogenic cholangitis. Am J Surg. 1998 Jul; 176(1):34-7. PMID: 9683129.
      View in: PubMed
    69. Harris H, Rockey DC, Chau P. Chylomicrons alter the hepatic distribution and cellular response to endotoxin in rats. Hepatology. 1998 May; 27(5):1341-8. PMID: 9581689.
      View in: PubMed
    70. Glasgow RE, Visser BC, Harris H, Patti MG, Kilpatrick SJ, Mulvihill SJ. Changing management of gallstone disease during pregnancy. Surg Endosc. 1998 Mar; 12(3):241-6. PMID: 9502704.
      View in: PubMed
    71. Harris H, Schecter WP. Surgical risk assessment and management in patients with HIV disease. Gastroenterol Clin North Am. 1997 Jun; 26(2):377-91. PMID: 9187930.
      View in: PubMed
    72. Ghermay AP, Brady S, Havel RJ, Harris H, Rapp JH. Sepsis increases endocytosis of endotoxin into hepatocytes. Surgery. 1996 Aug; 120(2):389-93; discussion 393-4. PMID: 8751609.
      View in: PubMed
    73. Read TE, Harris H, Grunfeld C, Feingold KR, Kane JP, Rapp JH. The protective effect of serum lipoproteins against bacterial lipopolysaccharide. Eur Heart J. 1993 Dec; 14 Suppl K:125-9. PMID: 8131781.
      View in: PubMed
    74. Read TE, Harris H, Grunfeld C, Feingold KR, Calhoun MC, Kane JP, Rapp JH. Chylomicrons enhance endotoxin excretion in bile. Infect Immun. 1993 Aug; 61(8):3496-502. PMID: 8335381; PMCID: PMC281028.
    75. Harris H, Grunfeld C, Feingold KR, Read TE, Kane JP, Jones AL, Eichbaum EB, Bland GF, Rapp JH. Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. J Clin Invest. 1993 Mar; 91(3):1028-34. PMID: 8450032; PMCID: PMC288056.
    76. Eichbaum EB, Harris H, Kane JP, Rapp JH. Chylomicrons can inhibit endotoxin activity in vitro. J Surg Res. 1991 Nov; 51(5):413-6. PMID: 1758174.
      View in: PubMed
    77. Harris H, Eichbaum EB, Kane JP, Rapp JH. Detection of endotoxin in triglyceride-rich lipoproteins in vitro. J Lab Clin Med. 1991 Aug; 118(2):186-93. PMID: 1856581.
      View in: PubMed
    78. Harris H, Grunfeld C, Feingold KR, Rapp JH. Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice. J Clin Invest. 1990 Sep; 86(3):696-702. PMID: 2394827; PMCID: PMC296783.
    79. Harris H, Rapp JH, Reilly LM, Orlando PA, Krupski WC, Goldstone J. Saphenous vein bypass to pedal arteries. An aggressive strategy for foot salvage. Arch Surg. 1989 Oct; 124(10):1232-5; discussion 1235-6. PMID: 2802989.
      View in: PubMed
    80. Pan X, Rapp JH, Harris H, Krupski WC, Hale JD, Sheldon P, Kaufman L. Identification of aortic thrombus by magnetic resonance imaging. J Vasc Surg. 1989 Jun; 9(6):801-5. PMID: 2724465.
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    81. Rapp JH, Harris H, Hamilton RL, Krupski WC, Reilly LM, Ehrenfeld WK, Stoney RJ, Goldstone J, Kane JP. Particle size distribution of lipoproteins from human atherosclerotic plaque: a preliminary report. J Vasc Surg. 1989 Jan; 9(1):81-8. PMID: 2911145.
      View in: PubMed
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