Tamara Alliston, PhD
|School||UCSF School of Medicine|
|Address||513 Parnassus Ave, Med Sci|
San Francisco CA 94143
Our research focuses on the mechanobiologic pathways controlling stem cell and skeletal cell differentiation in bone and cartilage. We seek to understand how these pathways maintain the mechanical integrity of the healthy skeleton, and how this is disrupted in skeletal diseases like arthritis and osteoporosis.
In particular, we study the mechanobiology of TGFß in the skeleton. To answer these questions we combine molecular, cellular, physiologic, bioengineering, and materials science approaches. This interdisciplinary approach will advance the development of therapies that can prevent skeletal disease and improve the speed and success of skeletal tissue regeneration.
Skeletal cell differentiation
, bone quality
, extracellular matrix
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