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Salivary gland-like tumors of the breast: Histopathologic and genetic features with clinical implications. Semin Diagn Pathol. 2024 Oct 05.
Schwartz CJ, Krings G. PMID: 39389890.
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PubMed Mentions: Fields:
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Targeted DNA Sequencing in Diagnosis of Malignant Phyllodes Tumors With Emphasis on Tumors With Keratin and p63 Expression. Mod Pathol. 2024 Aug 21; 37(12):100593.
Ye J, Theparee T, Bean GR, Rutland CD, Schwartz CJ, Vohra P, Allard G, Wang A, Hosfield EM, Peng Y, Chen YY, Krings G. PMID: 39154782.
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PubMed Mentions: Fields:
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A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170). Cancer Res Commun. 2024 Jul 01; 4(7):1793-1801.
Maldonado E, Rathmell WK, Shapiro GI, Takebe N, Rodon J, Mahalingam D, Trikalinos NA, Kalebasty AR, Parikh M, Boerner SA, Balido C, Krings G, Burns TF, Bergsland EK, Munster PN, Ashworth A, LoRusso P, Aggarwal RR. PMID: 38920407; PMCID: PMC11264598.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Percutaneous Balloon-Expandable Stent Implantation to Treat Transverse Aortic Arch Obstruction: Medium- to Long-Term Outcomes of a Retrospective Multicenter Study. Circ Cardiovasc Interv. 2024 Jul; 17(7):e013729.
Salavitabar A, Eisner M, Armstrong AK, Boe BA, Chisolm JL, Cheatham JP, Cheatham SL, Forbes T, Jones TK, Krings GJ, Morray BH, Steinberg ZL, Akam-Venkata J, Voskuil M, Berman DP. PMID: 38666384.
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Translation:
Humans
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The impact of unilateral pulmonary artery stenosis on right ventricular to pulmonary arterial coupling in patients with transposition of the great arteries. Catheter Cardiovasc Interv. 2024 May; 103(6):943-948.
Joosen RS, Voskuil M, Krings GJ, Handoko ML, Dickinson MG, van de Veerdonk MC, Breur JMPJ. PMID: 38577955.
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PubMed Mentions: Fields:
Translation:
Humans
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Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery. Clin Cancer Res. 2024 02 16; 30(4):729-740.
Albain KS, Yau C, Petricoin EF, Wolf DM, Lang JE, Chien AJ, Haddad T, Forero-Torres A, Wallace AM, Kaplan H, Pusztai L, Euhus D, Nanda R, Elias AD, Clark AS, Godellas C, Boughey JC, Isaacs C, Tripathy D, Lu J, Yung RL, Gallagher RI, Wulfkuhle JD, Brown-Swigart L, Krings G, Chen YY, Potter DA, Stringer-Reasor E, Blair S, Asare SM, Wilson A, Hirst GL, Singhrao R, Buxton M, Clennell JL, Sanil A, Berry S, Asare AL, Matthews JB, DeMichele AM, Hylton NM, Melisko M, Perlmutter J, Rugo HS, Symmans WF, Van't Veer LJ, Yee D, Berry DA, Esserman LJ. PMID: 38109213; PMCID: PMC10956403.
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PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Management of Concurrent Malignant Phyllodes Tumor and Invasive Breast Carcinoma. Adv Radiat Oncol. 2024 May; 9(5):101448.
Chen JJ, Zhu I, Patel A, Krings G, Chen YY, Yuen F, Mukhtar RA, Melisko M, Singer L, Park CC, Prionas ND. PMID: 38550370; PMCID: PMC10965428.
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PubMed Mentions:
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The effects of percutaneous branch pulmonary artery interventions on exercise capacity, lung perfusion, and right ventricular function in biventricular CHD: a systematic review. Cardiol Young. 2024 Mar; 34(3):473-482.
Joosen RS, Frissen JPB, van den Hoogen A, Krings GJ, Voskuil M, Slieker MG, Breur JMPJ. PMID: 38258453.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Clinicopathologic and genetic analysis of invasive breast carcinomas in women with germline CHEK2 variants. Breast Cancer Res Treat. 2024 Feb; 204(1):171-179.
Schwartz CJ, Khorsandi N, Blanco A, Mukhtar RA, Chen YY, Krings G. PMID: 38091153; PMCID: PMC10806021.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Right ventricular to pulmonary arterial coupling in patients with repaired tetralogy of Fallot: a case series. Eur Heart J Case Rep. 2023 Dec; 7(12):ytad583.
Joosen RS, Breur JMPJ, Wessels JN, Krings GJ, Voskuil M, de Man FS, van de Veerdonk MC. PMID: 38046648; PMCID: PMC10691650.
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PubMed Mentions:
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Malignant phyllodes tumour with lymph node metastasis: a diagnostic conundrum resolved by next generation DNA sequencing. Histopathology. 2024 Jan; 84(2):409-411.
Schwartz CJ, Krings G, Chen YY. PMID: 37706238.
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Translation:
Humans
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Solid-Basaloid Adenoid Cystic Carcinoma of the Breast: An Aggressive Subtype Enriched for Notch Pathway and Chromatin Modifier Mutations With MYB Overexpression. Mod Pathol. 2023 Dec; 36(12):100324.
Shamir ER, Bean GR, Schwartz CJ, Vohra P, Wang A, Allard GM, Wolsky RJ, Garcia JJ, Chen YY, Krings G. PMID: 37660928.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Comparison of Four-Dimensional Flow MRI, Two-Dimensional Phase-Contrast MRI and Echocardiography in Transposition of the Great Arteries. Pediatr Cardiol. 2024 Dec; 45(8):1627-1635.
Warmerdam EG, Westenberg JJM, Voskuil M, Rijnberg FM, Roest AAW, Lamb HJ, van Wijk B, Sieswerda GT, Doevendans PA, Ter Heide H, Krings GJ, Leiner T, Grotenhuis HB. PMID: 37488239; PMCID: PMC11442473.
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PubMed Mentions: Fields:
Translation:
Humans
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Genetic and Immunohistochemical Profiling of Mammary Hidradenoma and Comparison to Mucoepidermoid Carcinoma. Mod Pathol. 2023 Oct; 36(10):100270.
Black MA, Neumann NM, Krings G, Najjar S, Troxell ML, Wang A, Devine WP, Vohra P, Gasper C, Chen YY, Cohen JN, Bean GR. PMID: 37422157.
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PubMed Mentions:
3 Fields:
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Low-grade fibromyxoid sarcoma of the breast: genetic characterization and immunohistochemical comparison to morphologic mimics. Hum Pathol. 2023 09; 139:17-26.
Cloutier JM, Moreland A, Wang L, Kunder CA, Allard G, Wang A, Krings G, Charville GW, Bean GR. PMID: 37392946.
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PubMed Mentions: Fields:
Translation:
Humans
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A phase 2 study of the WEE1 inhibitor AZD1775 in SETD2-deficient advanced solid tumor malignancies. Journal of Clinical Oncology. 2023 May 31; 41(16_suppl):3104-3104.
Maldonado ME, Rathmell RW, Shapiro SG, Rodon Ahnert RJ, Mahalingam MD, Trikalinos TN, Rezazadeh RA, Adorno Febles AV, Parikh PM, Boerner BS, Krings KG, Takebe TN, LoRusso LP, Aggarwal AR. .
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Triple-Negative Apocrine Carcinomas: Toward a Unified Group With Shared Molecular Features and Clinical Behavior. Mod Pathol. 2023 05; 36(5):100125.
Schwartz CJ, Ruiz J, Bean GR, Sirohi D, Joseph NM, Hosfield EM, Jacobs TW, Mukhtar RA, Chen YY, Krings G. PMID: 36870308.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Atypical Lobular Hyperplasia and Lobular Carcinoma In Situ. . 2022 Nov 24; 615-654.
Krings KG, Hwang HH, Chen CY. .
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Fibroepithelial Lesions. . 2022 Nov 24; 253-330.
Krings KG, Chen CY. .
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Less Common Triple-Negative Breast Cancers. . 2022 Nov 24; 463-573.
Vohra VP, Chen CY, Krings KG. .
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Association of Residual Ductal Carcinoma In Situ With Breast Cancer Recurrence in the Neoadjuvant I-SPY2 Trial. JAMA Surg. 2022 11 01; 157(11):1034-1041.
Osdoit M, Yau C, Symmans WF, Boughey JC, Ewing CA, Balassanian R, Chen YY, Krings G, Wallace AM, Zare S, Fadare O, Lancaster R, Wei S, Godellas CV, Tang P, Tuttle TM, Klein M, Sahoo S, Hieken TJ, Carter JM, Chen B, Ahrendt G, Tchou J, Feldman M, Tousimis E, Zeck J, Jaskowiak N, Sattar H, Naik AM, Lee MC, Rosa M, Khazai L, Rendi MH, Lang JE, Lu J, Tawfik O, Asare SM, Esserman LJ, Mukhtar RA. PMID: 36069821; PMCID: PMC9453630.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Correction to: Genetic and immunohistochemical profiling of small cell and large cell neuroendocrine carcinomas of the breast. Mod Pathol. 2022 Oct; 35(10):1494-1495.
Bean GR, Najjar S, Shin SJ, Hosfield EM, Caswell-Jin JL, Urisman A, Jones KD, Chen YY, Krings G. PMID: 35697932; PMCID: PMC9514987.
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PubMed Mentions: Fields:
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A 3D printed pulmonary mock loop for hemodynamic studies in congenital heart disease. Biomed Phys Eng Express. 2022 09 05; 8(6).
Conijn M, Wintermans LM, Metselaar R, Ruisch J, Bax EA, van Egmond CAW, Nieuwenstein B, Warmerdam EG, Krings GJ. PMID: 35970091.
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PubMed Mentions: Fields:
Translation:
Humans
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Genetic and immunohistochemical profiling of small cell and large cell neuroendocrine carcinomas of the breast. Mod Pathol. 2022 10; 35(10):1349-1361.
Bean GR, Najjar S, Shin SJ, Hosfield EM, Caswell-Jin JL, Urisman A, Jones KD, Chen YY, Krings G. PMID: 35590107; PMCID: PMC9514991.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Treatment Efficacy Score-continuous residual cancer burden-based metric to compare neoadjuvant chemotherapy efficacy between randomized trial arms in breast cancer trials. Ann Oncol. 2022 08; 33(8):814-823.
Marczyk M, Mrukwa A, Yau C, Wolf D, Chen YY, Balassanian R, Nanda R, Parker BA, Krings G, Sattar H, Zeck JC, Albain KS, Boughey JC, Liu MC, Elias AD, Clark AS, Venters SJ, Shad S, Basu A, Asare SM, Buxton M, Asare AL, Rugo HS, Perlmutter J, DeMichele AM, Yee D, Berry DA, Veer LV, Symmans WF, Esserman L, Pusztai L, I-SPY Consortium. PMID: 35513244.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Standardizing Pathologic Evaluation of Breast Carcinoma After Neoadjuvant Chemotherapy. Arch Pathol Lab Med. 2022 05 01; 147(5):591-603.
Sahoo S, Krings G, Chen YY, Carter JM, Chen B, Guo H, Hibshoosh H, Reisenbichler E, Fan F, Wei S, Khazai L, Balassanian R, Klein ME, Shad S, Venters SJ, Borowsky AD, Symmans WF, Ocal IT. PMID: 35976643.
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PubMed Mentions: Fields:
Translation:
Humans
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Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial. JAMA Oncol. 2021 Nov 01; 7(11):1654-1663.
Symmans WF, Yau C, Chen YY, Balassanian R, Klein ME, Pusztai L, Nanda R, Parker BA, Datnow B, Krings G, Wei S, Feldman MD, Duan X, Chen B, Sattar H, Khazai L, Zeck JC, Sams S, Mhawech-Fauceglia P, Rendi M, Sahoo S, Ocal IT, Fan F, LeBeau LG, Vinh T, Troxell ML, Chien AJ, Wallace AM, Forero-Torres A, Ellis E, Albain KS, Murthy RK, Boughey JC, Liu MC, Haley BB, Elias AD, Clark AS, Kemmer K, Isaacs C, Lang JE, Han HS, Edmiston K, Viscusi RK, Northfelt DW, Khan QJ, Leyland-Jones B, Venters SJ, Shad S, Matthews JB, Asare SM, Buxton M, Asare AL, Rugo HS, Schwab RB, Helsten T, Hylton NM, van 't Veer L, Perlmutter J, DeMichele AM, Yee D, Berry DA, Esserman LJ. PMID: 34529000; PMCID: PMC8446908.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection. NPJ Breast Cancer. 2021 May 25; 7(1):59.
Glencer AC, Wong JM, Hylton NM, Krings G, McCune E, Rothschild HT, Loveday TA, Alvarado MD, Esserman LJ, Campbell MJ, Campbell MJ. PMID: 34035311; PMCID: PMC8149838.
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PubMed Mentions:
5
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Predicted sensitivity to endocrine therapy for stage II-III hormone receptor-positive and HER2-negative (HR+/HER2-) breast cancer before chemo-endocrine therapy. Ann Oncol. 2021 05; 32(5):642-651.
Du L, Yau C, Brown-Swigart L, Gould R, Krings G, Hirst GL, Bedrosian I, Layman RM, Carter JM, Klein M, Venters S, Shad S, van der Noordaa M, Chien AJ, Haddad T, Isaacs C, Pusztai L, Albain K, Nanda R, Tripathy D, Liu MC, Boughey J, Schwab R, Hylton N, DeMichele A, Perlmutter J, Yee D, Berry D, Van't Veer L, Valero V, Esserman LJ, Symmans WF. PMID: 33617937.
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PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
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Abstract PS1-03: Active surveillance for DCIS: Clinical outcomes at 5.6 years mean follow-up. Cancer Research. 2021 Feb 15; 81(4_Supplement):ps1-03-ps1-03.
Brabham BC, Mukhtar MR, Liang LA, Kim KP, Hirst HG, Basu BA, Greenwood GH, Freimanis FR, Borowsky BA, Hwang HS, Baehner BR, Krings KG, Hylton HN, Esserman EL. .
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Abstract PS4-09: Pathologic features of the inter-regimen biopsy predict response to neoadjuvant therapy in the I-SPY 2 TRIAL. Cancer Research. 2021 Feb 15; 81(4_Supplement):ps4-09-ps4-09.
Carter CJ, Klein KM, Venters VS, Rabe RK, Ocal OI, Singh SK, Wolf WD, Sahoo SS, Harada HS, Khazai KL, Harigopal HM, Borowsky BA, Krings KG, Balassanian BR, Chen CY, Cole CK, Shad SS, Delson DA, Brown-Swigart BL, Esserman EL, van ‘t Veer vL, Symmans SW. .
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Inflammation Mediates the Development of Aggressive Breast Cancer Following Radiotherapy. Clin Cancer Res. 2021 03 15; 27(6):1778-1791.
Ma L, Gonzalez-Junca A, Zheng Y, Ouyang H, Illa-Bochaca I, Horst KC, Krings G, Wang Y, Fernandez-Garcia I, Chou W, Barcellos-Hoff MH. PMID: 33402361; PMCID: PMC7956216.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Low-grade endometrial stromal sarcoma metastatic to the breast: Immunohistochemical and molecular characterization of an unusual mimic of mammary myofibroblastoma. Human Pathology Case Reports. 2020 Nov 1; 22:200447.
Elliott ED, Pekmezci PM, Geiersbach GK, Krings KG, Rabban RJ, Zaloudek ZC, Chen CY. .
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Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial. JAMA Oncol. 2020 09 01; 6(9):1355-1362.
I-SPY2 Trial Consortium, Yee D, DeMichele AM, Yau C, Isaacs C, Symmans WF, Albain KS, Chen YY, Krings G, Wei S, Harada S, Datnow B, Fadare O, Klein M, Pambuccian S, Chen B, Adamson K, Sams S, Mhawech-Fauceglia P, Magliocco A, Feldman M, Rendi M, Sattar H, Zeck J, Ocal IT, Tawfik O, LeBeau LG, Sahoo S, Vinh T, Chien AJ, Forero-Torres A, Stringer-Reasor E, Wallace AM, Pusztai L, Boughey JC, Ellis ED, Elias AD, Lu J, Lang JE, Han HS, Clark AS, Nanda R, Northfelt DW, Khan QJ, Viscusi RK, Euhus DM, Edmiston KK, Chui SY, Kemmer K, Park JW, Liu MC, Olopade O, Leyland-Jones B, Tripathy D, Moulder SL, Rugo HS, Schwab R, Lo S, Helsten T, Beckwith H, Haugen P, Hylton NM, Van't Veer LJ, Perlmutter J, Melisko ME, Wilson A, Peterson G, Asare AL, Buxton MB, Paoloni M, Clennell JL, Hirst GL, Singhrao R, Steeg K, Matthews JB, Asare SM, Sanil A, Berry SM, Esserman LJ, Berry DA. PMID: 32701140; PMCID: PMC7378873.
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PubMed Mentions:
78 Fields:
Translation:
Humans
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A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population. Breast Cancer Res. 2020 07 31; 22(1):81.
Kang T, Yau C, Wong CK, Sanborn JZ, Newton Y, Vaske C, Benz SC, Krings G, Camarda R, Henry JE, Stuart J, Powell M, Benz CC. PMID: 32736587; PMCID: PMC7395362.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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A phase Ib trial of the cyclin-dependent kinase inhibitor dinaciclib (dina) in combination with pembrolizumab (P) in patients with advanced triple-negative breast cancer (TNBC) and response correlation with MYC-overexpression. Journal of Clinical Oncology. 2020 May 20; 38(15_suppl):1076-1076.
Chien CA, Gliwa GA, Rahmaputri RS, Dittrich DH, Majure MM, Rugo RH, Melisko MM, Munster MP, Park PJ, Moasser MM, Matloubian MM, Lea LT, Rohrberg RJ, Krings KG, Goga GA. .
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Evaluation of ductal carcinoma in situ grade via triple-modal molecular imaging of B7-H3 expression. NPJ Breast Cancer. 2020; 6:14.
Bachawal S, Bean GR, Krings G, Wilson KE. PMID: 32377564; PMCID: PMC7190737.
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PubMed Mentions:
7
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Mitotic score and pleomorphic histology in invasive lobular carcinoma of the breast: impact on disease-free survival. Breast Cancer Res Treat. 2020 May; 181(1):23-29.
Mukhtar RA, Krings G, Chen YY, Mamounas ME, Fahrner-Scott K, Wong J, Alvarado M, Ewing C, Esserman LJ, Rugo H. PMID: 32240457.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Phase II Single-Arm Study of Preoperative Letrozole for Estrogen Receptor-Positive Postmenopausal Ductal Carcinoma In Situ: CALGB 40903 (Alliance). J Clin Oncol. 2020 04 20; 38(12):1284-1292.
Hwang ES, Hyslop T, Hendrix LH, Duong S, Bedrosian I, Price E, Caudle A, Hieken T, Guenther J, Hudis CA, Winer E, Lyss AP, Dickson-Witmer D, Hoefer R, Ollila DW, Hardman T, Marks J, Chen YY, Krings G, Esserman L, Hylton N. PMID: 32125937; PMCID: PMC7164489.
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PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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Primary mammary angiosarcomas harbor frequent mutations in KDR and PIK3CA and show evidence of distinct pathogenesis. Mod Pathol. 2020 08; 33(8):1518-1526.
Beca F, Krings G, Chen YY, Hosfield EM, Vohra P, Sibley RK, Troxell ML, West RB, Allison KH, Bean GR. PMID: 32123305.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Abstract P3-08-20: The normal breast Active transcriptome associated with future breast cancer risk is driven by a dysregulated adipocyte microenvironment. Cancer Research. 2020 Feb 15; 80(4_Supplement):p3-08-20-p3-08-20.
Benz BC, Kang KT, Yau YC, Wong WC, Newton NY, Vaske VC, Benz BS, Krings KG, Camarda CR, Henry HJ, Stuart SJ, Powell PM. .
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Abstract P6-10-02: Assessing biomarkers to inform treatment de-escalation: Mid-treatment biopsy cellularity predicts pCR in the I-SPY 2 Trial. Cancer Research. 2020 Feb 15; 80(4_Supplement):p6-10-02-p6-10-02.
Venters VS, Wolf WD, Brown-Swigart BL, Yau YC, Delson DA, Parker PB, Balassanian BR, Carter CJ, Chen CY, Cole CK, Khazai KL, Klein KM, Kokh KD, Krings KG, Sahoo SS, Wei WJ, Esserman EL, van't Veer vL, Symmans SW. .
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Genetic analysis of pleomorphic and florid lobular carcinoma in situ variants: frequent ERBB2/ERBB3 alterations and clonal relationship to classic lobular carcinoma in situ and invasive lobular carcinoma. Mod Pathol. 2020 06; 33(6):1078-1091.
Shamir ER, Chen YY, Krings G. PMID: 31907376.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Immunohistochemical analysis of IDH2 R172 hotspot mutations in breast papillary neoplasms: applications in the diagnosis of tall cell carcinoma with reverse polarity. Mod Pathol. 2020 06; 33(6):1056-1064.
Pareja F, da Silva EM, Frosina D, Geyer FC, Lozada JR, Basili T, Da Cruz Paula A, Zhong E, Derakhshan F, D'Alfonso T, Wen HY, Giri DD, Hayes MM, Krings G, Bhargava R, Palazzo JP, Rakha EA, Hoda SA, Sanders ME, Collins LC, Schnitt SJ, Chen YY, Weigelt B, Jungbluth AA, Reis-Filho JS, Brogi E. PMID: 31896809; PMCID: PMC7286791.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Pan-TRK Immunohistochemistry: A Useful Diagnostic Adjunct For Secretory Carcinoma of the Breast. Am J Surg Pathol. 2019 12; 43(12):1693-1700.
Harrison BT, Fowler E, Krings G, Chen YY, Bean GR, Vincent-Salomon A, Fuhrmann L, Barnick SE, Chen B, Hosfield EM, Hornick JL, Schnitt SJ. PMID: 31498178.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Abstract 3314: Normal breast tissue at risk for cancer development: A breast cancer initiating role for mammary adipocytes. Prevention, Early Detection, and Interception. 2019 Jul 1; 3314-3314.
Kang KT, Yau YC, Benz BS, Krings KG, Camarda CR, Henry HJ, Powell PM, Benz BC. .
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Genomic profiling of combined hepatocellular-cholangiocarcinoma reveals similar genetics to hepatocellular carcinoma. J Pathol. 2019 06; 248(2):164-178.
Joseph NM, Tsokos CG, Umetsu SE, Shain AH, Kelley RK, Onodera C, Bowman S, Talevich E, Ferrell LD, Kakar S, Krings G. PMID: 30690729.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Pleomorphic and Florid Lobular Carcinoma In Situ Variants of the Breast: A Clinicopathologic Study of 85 Cases With and Without Invasive Carcinoma From a Single Academic Center. Am J Surg Pathol. 2019 03; 43(3):399-408.
Shamir ER, Chen YY, Chu T, Pekmezci M, Rabban JT, Krings G. PMID: 30489319.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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CRTC1-MAML2 fusion in mucoepidermoid carcinoma of the breast. Histopathology. 2019 Feb; 74(3):463-473.
Bean GR, Krings G, Otis CN, Solomon DA, García JJ, van Zante A, Camelo-Piragua S, van Ziffle J, Chen YY. PMID: 30380176.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer. Nat Med. 2019 01; 25(1):111-118.
Shah KN, Bhatt R, Rotow J, Rohrberg J, Olivas V, Wang VE, Hemmati G, Martins MM, Maynard A, Kuhn J, Galeas J, Donnella HJ, Kaushik S, Ku A, Dumont S, Krings G, Haringsma HJ, Robillard L, Simmons AD, Harding TC, McCormick F, Goga A, Blakely CM, Bivona TG, Bandyopadhyay S. PMID: 30478424; PMCID: PMC6324945.
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PubMed Mentions:
132 Fields:
Translation:
HumansAnimalsCells
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DICER1 mutations are frequent in müllerian adenosarcomas and are independent of rhabdomyosarcomatous differentiation. Mod Pathol. 2019 02; 32(2):280-289.
Bean GR, Anderson J, Sangoi AR, Krings G, Garg K. PMID: 30266945.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Identification of high-risk human papillomavirus and Rb/E2F pathway genomic alterations in mutually exclusive subsets of colorectal neuroendocrine carcinoma. Mod Pathol. 2019 02; 32(2):290-305.
Shamir ER, Devine WP, Pekmezci M, Umetsu SE, Krings G, Federman S, Cho SJ, Saunders TA, Jen KY, Bergsland E, Jones K, Kim GE, Kakar S, Chiu CY, Joseph NM. PMID: 30237525.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer. J Natl Cancer Inst. 2018 07 01; 110(7):726-733.
Lindström LS, Yau C, Czene K, Thompson CK, Hoadley KA, Van't Veer LJ, Balassanian R, Bishop JW, Carpenter PM, Chen YY, Datnow B, Hasteh F, Krings G, Lin F, Zhang Y, Nordenskjöld B, Stål O, Benz CC, Fornander T, Borowsky AD, Esserman LJ, STO Trialists Group. PMID: 29361175; PMCID: PMC6037086.
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PubMed Mentions:
46 Fields:
Translation:
Humans
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Abstract 1957: Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer. Experimental and Molecular Therapeutics. 2018 Jul 1; 1957-1957.
Shah SK, Bhatt BR, Rotow RJ, Rohrberg RJ, Olivas OV, Hemmati HG, Krings KG, Haringsma HH, Simmons SA, Harding HT, Goga GA, Blakely BC, Bivona BT, Bandyopadhyay BS. .
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Publisher Site Mentions:
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Genomic profiling of metaplastic breast carcinomas reveals genetic heterogeneity and relationship to ductal carcinoma. Mod Pathol. 2018 11; 31(11):1661-1674.
Krings G, Chen YY. PMID: 29946183.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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EWSR1-NFATC2 gene fusion in a soft tissue tumor with epithelioid round cell morphology and abundant stroma: a case report and review of the literature. Hum Pathol. 2018 11; 81:281-290.
Cohen JN, Sabnis AJ, Krings G, Cho SJ, Horvai AE, Davis JL. PMID: 29626598; PMCID: PMC8104452.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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452 (PB-085) The impact of mitotic score versus pleomorphic subtype on disease free survival in invasive lobular carcinoma of the breast. European Journal of Cancer. 2018 Apr 1; 92:s132.
Mamounas MM, Wong WJ, Fahrner-Scott FK, Chen CY, Krings KG, Ewing EC, Esserman EL, Alvarado AM, Rugo RH, Mukhtar MR. .
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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HDAC inhibition potentiates immunotherapy in triple negative breast cancer. Oncotarget. 2017 Dec 26; 8(69):114156-114172.
Terranova-Barberio M, Thomas S, Ali N, Pawlowska N, Park J, Krings G, Rosenblum MD, Budillon A, Munster PN. PMID: 29371976; PMCID: PMC5768393.
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PubMed Mentions:
96 Fields:
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Comprehensive analysis of normal adjacent to tumor transcriptomes. Nat Commun. 2017 10 20; 8(1):1077.
Aran D, Camarda R, Odegaard J, Paik H, Oskotsky B, Krings G, Goga A, Sirota M, Butte AJ. PMID: 29057876; PMCID: PMC5651823.
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PubMed Mentions:
272 Fields:
Translation:
HumansCells
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Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors. Breast Cancer Res. 2017 Sep 11; 19(1):107.
Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Bo P, Hann B, Coppé JP, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer RJ, de Vries N, Rosing H, Pawlowska N, Thomas S, Dhawan M, Aggarwal R, Munster PN, Esserman LJ, Ruan W, Wu AHB, Yee D, Dartois V, Savic RM, Wolf DM, van 't Veer L. PMID: 28893315; PMCID: PMC5594551.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Myofibroblastic, fibroblastic and myoid lesions of the breast. Semin Diagn Pathol. 2017 Sep; 34(5):427-437.
Krings G, McIntire P, Shin SJ. PMID: 28751104.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Fibroepithelial lesions; The WHO spectrum. Semin Diagn Pathol. 2017 Sep; 34(5):438-452.
Krings G, Bean GR, Chen YY. PMID: 28688536.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Genomic profiling of breast secretory carcinomas reveals distinct genetics from other breast cancers and similarity to mammary analog secretory carcinomas. Mod Pathol. 2017 08; 30(8):1086-1099.
Krings G, Joseph NM, Bean GR, Solomon D, Onodera C, Talevich E, Yeh I, Grenert JP, Hosfield E, Crawford ED, Jordan RC, van Zante A, Zaloudek C, Shin SJ, Chen YY. PMID: 28548128.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Targeted next-generation DNA sequencing of paired tumor and normal DNA to reveal frequent actionable germline alterations. Journal of Clinical Oncology. 2017 May 20; 35(15_suppl):11575-11575.
Korn KW, Yey YI, Van Ziffle VJ, Grenert GJ, Joseph JN, Solomon SD, Laurance LM, Talevich TE, Onodera OC, Krings KG, Stohr SB, Blanco BA, Bastian BB. .
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The molecular basis of breast cancer pathological phenotypes. J Pathol. 2017 Feb; 241(3):375-391.
Heng YJ, Lester SC, Tse GM, Factor RE, Allison KH, Collins LC, Chen YY, Jensen KC, Johnson NB, Jeong JC, Punjabi R, Shin SJ, Singh K, Krings G, Eberhard DA, Tan PH, Korski K, Waldman FM, Gutman DA, Sanders M, Reis-Filho JS, Flanagan SR, Gendoo DM, Chen GM, Haibe-Kains B, Ciriello G, Hoadley KA, Perou CM, Beck AH. PMID: 27861902; PMCID: PMC5499709.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast. Breast Cancer Res Treat. 2017 01; 161(1):17-28.
Campbell MJ, Campbell MJ, Baehner F, O'Meara T, Ojukwu E, Han B, Mukhtar R, Tandon V, Endicott M, Zhu Z, Wong J, Krings G, Au A, Gray JW, Esserman L. PMID: 27785654; PMCID: PMC5225037.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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'Non-classical' HER2 FISH results in breast cancer: a multi-institutional study. Mod Pathol. 2017 02; 30(2):227-235.
Ballard M, Jalikis F, Krings G, Schmidt RA, Chen YY, Rendi MH, Dintzis SM, Jensen KC, West RB, Sibley RK, Troxell ML, Allison KH. PMID: 27739440.
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PubMed Mentions:
27 Fields:
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Humans
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Abstract 2673: Inhibition of fatty-acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Molecular and Cellular Biology, Genetics. 2016 Jul 15; 2673-2673.
Camarda CR, Zhou ZA, Kohnz KR, Balakrishnan BS, Mahieu MC, Anderton AB, Eyob EH, Kajimura KS, Tward TA, Krings KG, Nomura ND, Goga GA. .
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Proliferative index facilitates distinction between benign biliary lesions and intrahepatic cholangiocarcinoma. Hum Pathol. 2016 11; 57:61-67.
Tsokos CG, Krings G, Yilmaz F, Ferrell LD, Gill RM. PMID: 27396933; PMCID: PMC5250508.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Small-cell predominant extranodal NK/T cell lymphoma, nasal type: clinicopathological analysis of a series of cases diagnosed in a Western population. Histopathology. 2016 Oct; 69(4):667-79.
McKelvie PA, Climent F, Krings G, Hasserjian RP, Abramson JS, Pilch BZ, Harris NL, Ferry JA, Zukerberg LR, Sohani AR. PMID: 27144366.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity. Mod Pathol. 2016 09; 29(9):1012-27.
Liu SY, Joseph NM, Ravindranathan A, Stohr BA, Greenland NY, Vohra P, Hosfield E, Yeh I, Talevich E, Onodera C, Van Ziffle JA, Grenert JP, Bastian BC, Chen YY, Krings G. PMID: 27255162.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells. Elife. 2016 Mar 07; 5:e10647.
Myers SA, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, Thomas S, Maynard J, Broeker M, Thomson M, Pollard K, Yamanaka S, Burlingame AL, Panning B. PMID: 26949256; PMCID: PMC4841768.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat Med. 2016 04; 22(4):427-32.
Camarda R, Zhou AY, Kohnz RA, Balakrishnan S, Mahieu C, Anderton B, Eyob H, Kajimura S, Tward A, Krings G, Nomura DK, Goga A. PMID: 26950360; PMCID: PMC4892846.
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PubMed Mentions:
273 Fields:
Translation:
HumansCells
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SATB2 Expression Distinguishes Ovarian Metastases of Colorectal and Appendiceal Origin From Primary Ovarian Tumors of Mucinous or Endometrioid Type. Am J Surg Pathol. 2016 Mar; 40(3):419-32.
Moh M, Krings G, Ates D, Aysal A, Kim GE, Rabban JT. PMID: 26551622.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Abstract PD3-05: Inhibition of fatty-acid oxidation as a therapy for triple-negative breast cancer. Poster Discussion Abstracts. 2016 Feb 15; pd3-05-pd3-05.
Goga GA, Camarda CR, Zhou ZA, Kohnz KR, Balakrishnan BS, Anderton AB, Mahieu MC, Eyob EH, Krings KG, Nomura ND. .
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Fibroepithelial Lesions. A Comprehensive Guide to Core Needle Biopsies of the Breast. 2016 Jan 1; 241-319.
Krings KG, Chen CY. .
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Less Common Triple Negative Breast Cancers. A Comprehensive Guide to Core Needle Biopsies of the Breast. 2016 Jan 1; 445-518.
Vohra VP, Krings KG, Chen CY. .
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Abstract C61: Non-homogeneous drug penetrance of veliparib measured in triple negative breast tumors. Drug Metabolism, Transport, and Biodistribution. 2015 Dec 1; c61-c61.
Bartelink BI, Prideaux PB, Krings KG, Wilmes WL, Lee LP, Hann HB, Coppé CJ, Heditsian HD, Swigart-Brown SL, Jones JE, Magnitsky MS, Keizer KR, Esserman EL, Ruan RW, Wu WA, Yee YD, Dartois DV, Wolf WD, Savic SR, vantVeer vL. .
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Spatial distribution of veliparib measured by matrix-assisted laser desorption ionization mass spectrometry in triple-negative breast cancer tumors. Journal of Clinical Oncology. 2014 Sep 10; 32(26_suppl):161-161.
Bartelink BI, Prideaux PB, Hann HB, Krings KG, Coppe CJ, Brown Swigart BL, Lee LE, Esserman EL, Yee YD, Wolf WD, Savic SR. .
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Diagnostic utility and sensitivities of GATA3 antibodies in triple-negative breast cancer. Hum Pathol. 2014 Nov; 45(11):2225-32.
Krings G, Nystrom M, Mehdi I, Vohra P, Chen YY. PMID: 25150746.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Predictive biomarkers of invasive carcinoma on excision in patients with a diagnosis of ductal carcinoma in situ of the breast by needle biopsy. Journal of Clinical Oncology. 2014 May 20; 32(15_suppl):e12029-e12029.
Mori MM, Krings KG, Chan CL, Wolf WD, Chen CY, Kerlikowske KK, Tlsty TT, Coppe CJ, Matsuda MN, Suzuki SK, Nakamura NS, van't Veer vL. .
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Aberrant centrizonal features in chronic hepatic venous outflow obstruction: centrilobular mimicry of portal-based disease. Am J Surg Pathol. 2014 Feb; 38(2):205-14.
Krings G, Can B, Ferrell L. PMID: 24418854.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Abstract P5-16-04: Predictive biomarkers for invasion on final pathology in patients with preoperative diagnosis of ductal carcinoma in situ of the breast by needle biopsy. Poster Session Abstracts. 2013 Dec 15; p5-16-04-p5-16-04.
Mori MM, Krings KG, Chan CL, Chen CY, Kerlikowske KK, Tlsty TT, Matsuda MN, Suzuki SK, van't Veer vL. .
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Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma. Mod Pathol. 2013 Jun; 26(6):782-91.
Krings G, Ramachandran R, Jain D, Wu TT, Yeh MM, Torbenson M, Kakar S. PMID: 23348905.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Ocular melanoma metastatic to the pancreas after a 28-year disease-free interval. Surgery. 2010 Jul; 148(1):151-4.
Vagefi PA, Stangenberg L, Krings G, Forcione DG, Wargo JA. PMID: 19744448.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):12831-6.
Bastia D, Zzaman S, Krings G, Saxena M, Peng X, Greenberg MM. PMID: 18708526; PMCID: PMC2529109.
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PubMed Mentions:
24 Fields:
Translation:
Cells
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Molecular architecture of a eukaryotic DNA replication terminus-terminator protein complex. Mol Cell Biol. 2006 Nov; 26(21):8061-74.
Krings G, Bastia D. PMID: 16940176; PMCID: PMC1636744.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Sap1p binds to Ter1 at the ribosomal DNA of Schizosaccharomyces pombe and causes polar replication fork arrest. J Biol Chem. 2005 Nov 25; 280(47):39135-42.
Krings G, Bastia D. PMID: 16195226.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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swi1- and swi3-dependent and independent replication fork arrest at the ribosomal DNA of Schizosaccharomyces pombe. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14085-90.
Krings G, Bastia D. PMID: 15371597; PMCID: PMC521093.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Chlamydophila pneumoniae induces ICAM-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB. Circ Res. 2003 May 30; 92(10):1130-7.
Vielma SA, Krings G, Lopes-Virella MF. PMID: 12714566.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Immunochemical characterization of purified human oxidized low-density lipoprotein antibodies. Clin Immunol. 2000 May; 95(2):135-44.
Virella G, Koskinen S, Krings G, Onorato JM, Thorpe SR, Lopes-Virella M. PMID: 10779407.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells