 Smriti Sangwan, PhD
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| Title(s) | Postdoctoral Scholar, Biochemistry and Biophysics |
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| School | School of Medicine |
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| Phone | 415-476-4636 |
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| vCard | Download vCard |
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 Biography | University of California, Los Angeles | Ph.D. | 2017 | Molecular Biology | | University of California, Los Angeles | M.S. | 2012 | Biomedical Engineering |
ORNG Applications Bibliographic
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Sangwan S, Sawaya MR, Murray KA, Hughes MP, Eisenberg DS. Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations. Protein Sci. 2018 Jul; 27(7):1231-1242. PMID: 29453800.
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Do TD, Sangwan S, de Almeida NEC, Ilitchev AI, Giammona M, Sawaya MR, Buratto SK, Eisenberg DS, Bowers MT. Distal amyloid ß-protein fragments template amyloid assembly. Protein Sci. 2018 Jul; 27(7):1181-1190. PMID: 29349888.
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Sangwan S, Zhao A, Adams KL, Jayson CK, Sawaya MR, Guenther EL, Pan AC, Ngo J, Moore DM, Soriaga AB, Do TD, Goldschmidt L, Nelson R, Bowers MT, Koehler CM, Shaw DE, Novitch BG, Eisenberg DS. Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A. 2017 08 15; 114(33):8770-8775. PMID: 28760994.
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Soriaga AB, Sangwan S, Macdonald R, Sawaya MR, Eisenberg D. Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets. J Phys Chem B. 2016 07 07; 120(26):5810-6. PMID: 26629790.
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Sangwan S, Eisenberg DS. Perspective on SOD1 mediated toxicity in Amyotrophic Lateral Sclerosis. Postepy Biochem. 2016; 62(3):362-369. PMID: 28132491.
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Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS. Structure of the toxic core of a-synuclein from invisible crystals. Nature. 2015 Sep 24; 525(7570):486-90. PMID: 26352473.
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Do TD, LaPointe NE, Sangwan S, Teplow DB, Feinstein SC, Sawaya MR, Eisenberg DS, Bowers MT. Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. J Phys Chem B. 2014 Jul 03; 118(26):7247-56. PMID: 24915112.
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