Shaeri Mukherjee, PhD

Title(s)Professor, Microbiology and Immunology
SchoolSchool of Medicine
Address513 Parnassus Ave, HSW, #1522
San Francisco CA 94143
Phone415-476-2826
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    Collapse Biography 
    Collapse Education and Training
    Albert Einstein College of Medicine, NYPh.D06/2007Cell Biology
    Yale University, CTPost-Doc12/2013Microbiology
    University of California, San Francisco, CA2021Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    Albert Einstein College of Medicine2008Julius Marmur Award for Outstanding Thesis
    Yale University2010Anna Fuller Fellowship
    Pew Charitable Trust2017Pew Scholar
    Chan Zuckerberg Initiative2022Chan Zuckerberg Investigator
    UCSF2023Bowes Biomedical Investigator

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Bowes Biomedical Investigator Program Jan 1, 2023 - Dec 31, 2027
    Role: Principal Investigator
    Role of HSC70 in protein synthesis
    NIH R01GM144378Jul 20, 2022 - Apr 30, 2026
    Role: Principal Investigator
    Chan Zuckerberg Investigator
    Chan Zuckerberg Initiative Jul 1, 2022 - Jun 30, 2027
    Role: Principal Investigator
    Turning bacterial pathogens into cell-biology tools
    Pew Charitable Trusts A129837Aug 1, 2017 - Jul 31, 2021
    Role: Principal Investigator
    Legionella effectors reveal novel signaling function for the ribosome quality control (RQC) pathway
    NIH R01GM140440Jun 15, 2016 - May 31, 2025
    Role: Principal Investigator
    Subversion of membrane transport pathways by Legionella pneumophila
    NIH R01AI118974Jun 15, 2016 - May 31, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila. Mol Biol Cell. 2024 Mar 01; 35(3):ar27. Steinbach A, Bhadkamkar V, Jimenez-Morales D, Stevenson E, Jang GM, Krogan NJ, Swaney DL, Mukherjee S. PMID: 38117589.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response. Nat Cell Biol. 2023 Nov; 25(11):1600-1615. Subramanian A, Wang L, Moss T, Voorhies M, Sangwan S, Stevenson E, Pulido EH, Kwok S, Chalkley RJ, Li KH, Krogan NJ, Swaney DL, Burlingame AL, Floor SN, Sil A, Walter P, Mukherjee S. PMID: 37857833.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila. bioRxiv. 2023 Aug 03. Steinbach AM, Bhadkamkar VL, Jimenez-Morales D, Stevenson E, Jang GM, Krogan NJ, Swaney DL, Mukherjee S. PMID: 37577546; PMCID: PMC10418220.
      View in: PubMed   Mentions:
    4. A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience. Nat Commun. 2022 11 10; 13(1):6805. Wang C, Wang B, Pandey T, Long Y, Zhang J, Oh F, Sima J, Guo R, Liu Y, Zhang C, Mukherjee S, Bassik M, Lin W, Deng H, Vale G, McDonald JG, Shen K, Ma DK. PMID: 36357390; PMCID: PMC9649747.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    5. Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors. Life Sci Alliance. 2021 12; 4(12). Ibe NU, Subramanian A, Mukherjee S. PMID: 34635501; PMCID: PMC8507491.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020 07; 583(7816):459-468. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, García-Sastre A, Shokat KM, Shoichet BK, Krogan NJ. PMID: 32353859; PMCID: PMC7431030.
      View in: PubMed   Mentions: 2284     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    7. "Make way": Pathogen exploitation of membrane traffic. Curr Opin Cell Biol. 2020 08; 65:78-85. Noack J, Mukherjee S. PMID: 32234681; PMCID: PMC7529693.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    8. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. bioRxiv. 2020 Mar 22. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Naing ZZC, Zhou Y, Peng S, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Shen W, Shi Y, Zhang Z, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Ramachandran R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Lin Y, Wankowicz SA, Bohn M, Trenker R, Young JM, Cavero D, Hiatt J, Roth T, Rathore U, Subramanian A, Noack J, Hubert M, Roesch F, Vallet T, Meyer B, White KM, Miorin L, Agard D, Emerman M, Ruggero D, García-Sastre A, Jura N, von Zastrow M, Taunton J, Schwartz O, Vignuzzi M, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor S, Fraser JS, Gross J, Sali A, Kortemme T, Beltrao P, Shokat K, Shoichet BK, Krogan NJ. PMID: 32511329; PMCID: PMC7239059.
      View in: PubMed   Mentions: 28  
    9. CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis. J Cell Biol. 2020 01 06; 219(1). Camus SM, Camus MD, Figueras-Novoa C, Boncompain G, Sadacca LA, Esk C, Bigot A, Gould GW, Kioumourtzoglou D, Perez F, Bryant NJ, Mukherjee S, Brodsky FM. PMID: 31863584; PMCID: PMC7039200.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    10. Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. Cell Host Microbe. 2019 10 09; 26(4):551-563.e6. Jeng EE, Bhadkamkar V, Ibe NU, Gause H, Jiang L, Chan J, Jian R, Jimenez-Morales D, Stevenson E, Krogan NJ, Swaney DL, Snyder MP, Mukherjee S, Bassik MC. PMID: 31540829; PMCID: PMC6800164.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    11. A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis. Cell Host Microbe. 2019 03 13; 25(3):454-462.e6. Moss SM, Taylor IR, Ruggero D, Gestwicki JE, Shokat KM, Mukherjee S. PMID: 30827827; PMCID: PMC6529236.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    12. How to rewire the host cell: A home improvement guide for intracellular bacteria. J Cell Biol. 2017 12 04; 216(12):3931-3948. Cornejo E, Schlaermann P, Mukherjee S. PMID: 29097627; PMCID: PMC5716269.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    13. Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):E4776-83. Levin RS, Hertz NT, Burlingame AL, Shokat KM, Mukherjee S. PMID: 27482120; PMCID: PMC4995946.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    14. Legionella suppresses the host unfolded protein response via multiple mechanisms. Nat Commun. 2015 Jul 29; 6:7887. Treacy-Abarca S, Mukherjee S. PMID: 26219498; PMCID: PMC4519984.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    15. Legionella pneumophila subversion of host vesicular transport by SidC effector proteins. Traffic. 2014 May; 15(5):488-99. Horenkamp FA, Mukherjee S, Alix E, Schauder CM, Hubber AM, Roy CR, Reinisch KM. PMID: 24483784; PMCID: PMC4041529.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    16. Structure of the Legionella effector AnkX reveals the mechanism of phosphocholine transfer by the FIC domain. EMBO J. 2013 May 15; 32(10):1469-77. Campanacci V, Mukherjee S, Roy CR, Cherfils J. PMID: 23572077; PMCID: PMC3655470.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    17. Subversion of membrane transport pathways by vacuolar pathogens. J Cell Biol. 2011 Dec 12; 195(6):943-52. Alix E, Mukherjee S, Roy CR. PMID: 22123831; PMCID: PMC3241728.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    18. Modulation of Rab GTPase function by a protein phosphocholine transferase. Nature. 2011 Aug 07; 477(7362):103-6. Mukherjee S, Liu X, Arasaki K, McDonough J, Galán JE, Roy CR. PMID: 21822290; PMCID: PMC3206611.
      View in: PubMed   Mentions: 168     Fields:    Translation:HumansAnimalsCells
    19. The Golgi protein p115 associates with gamma-tubulin and plays a role in Golgi structure and mitosis progression. J Biol Chem. 2011 Jun 17; 286(24):21915-26. Radulescu AE, Mukherjee S, Shields D. PMID: 21536679; PMCID: PMC3122246.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    20. Opposing action of casein kinase 1 and calcineurin in nucleo-cytoplasmic shuttling of mammalian translation initiation factor eIF6. J Biol Chem. 2011 Jan 28; 286(4):3129-38. Biswas A, Mukherjee S, Das S, Shields D, Chow CW, Maitra U. PMID: 21084295; PMCID: PMC3024805.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    21. Bacterial FIC Proteins AMP Up Infection. Sci Signal. 2009 Mar 17; 2(62):pe14. Roy CR, Mukherjee S. PMID: 19293428.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    22. Nuclear import is required for the pro-apoptotic function of the Golgi protein p115. J Biol Chem. 2009 Jan 16; 284(3):1709-17. Mukherjee S, Shields D. PMID: 19028683; PMCID: PMC2615508.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    23. Fragmentation of the Golgi apparatus: an early apoptotic event independent of the cytoskeleton. Traffic. 2007 Apr; 8(4):369-78. Mukherjee S, Chiu R, Leung SM, Shields D. PMID: 17394485.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    24. Characterization of Drosophila nitric oxide synthase: a biochemical study. Biochem Biophys Res Commun. 2003 Jun 27; 306(2):590-7. Sengupta R, Sahoo R, Mukherjee S, Regulski M, Tully T, Stuehr DJ, Ghosh S. PMID: 12804606.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    25. A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis. J Cell Biol. 2002 Nov 25; 159(4):637-48. Chiu R, Novikov L, Mukherjee S, Shields D. PMID: 12438416; PMCID: PMC2173109.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
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