Thomas Ferrin, PhD
|School||UCSF School of Pharmacy|
|Address||600 16th Street|
San Francisco CA 94158
My research lab develops software and advanced web-based resources for the integrated visualization and analysis of molecular structure at scales ranging from atomic to supramolecular. Our objective is to create methods and tools for handling the diverse types of data associated with these structures and their broader contexts, and then deploy these tools to study structure-function relationships to reveal the molecular mechanisms of biological processes. Our primary efforts are in visualization and analysis of protein structure at multiple scales, protein interaction and similarity networks, and defining principles by which enzyme structure mediates catalytic function. Our aims are to advance the understanding of the molecular basis of disease and phenotypic variation, annotate proteins of unknown function, identify targets for drug development, more effectively design drugs, and engineer proteins with new functions.
I'm also the director of the Resource for Biocomputing, Visualization, and Informatics, an NIH National Center for Research Resources Biomedical Technology Research Center.
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