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Tony Yang, MD, PhD

TitleAssociate Professor
SchoolUCSF School of Medicine
DepartmentPsychiatry
Address401 Parnassus Ave, LangPorter
San Francisco CA 94143
Phone415-476-7797
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    Collapse Research 
    Collapse Research Activities and Funding
    A Cross-Sectional and Longitudinal Functional MRI Study of Adolescent Depression
    NIH/NIMH R01MH085734Jul 1, 2010 - May 31, 2015
    Role: Principal Investigator
    A Cross-Sectional and Longitudinal Functional MRI Study of Adolescent Depression
    NIH/NIMH R01MH085734Jul 1, 2010 - May 31, 2015
    Role: Principal Investigator
    Magnetic Resonance Imaging in Depressed Adolescents
    NIH/NIMH K23MH070791Feb 15, 2005 - Jun 30, 2010
    Role: Principal Investigator
    Magnetic Resonance Imaging in Depressed Adolescents
    NIH/NIMH K23MH070791Feb 15, 2005 - Jun 30, 2010
    Role: Principal Investigator
    NEUROSCIENCES
    NIH/NIMH F30MH010174Mar 13, 1992
    Role: Principal Investigator
    NEUROSCIENCES
    NIH/NIMH F30MH010174Mar 13, 1992
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Selected Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Henje Blom E, Tymofiyeva O, Chesney MA, Ho TC, Moran P, Connolly CG, Duncan LG, Baldini L, Weng HY, Acree M, Goldman V, Hecht FM, Yang TT. Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study. Front Psychiatry. 2016; 7:208. PMID: 28138319.
      View in: PubMed
    2. Connolly CG, Ho TC, Blom EH, LeWinn KZ, Sacchet MD, Tymofiyeva O, Simmons AN, Yang T. Resting-state functional connectivity of the amygdala and longitudinal changes in depression severity in adolescent depression. J Affect Disord. 2016 Sep 23; 207:86-94. PMID: 27716542.
      View in: PubMed
    3. Scaffidi MA, Garg A, Ro B, Wang C, Yang TT, Plener IS, Grin A, Colak E, Grover SC. Esophageal Intramural Pseudodiverticulosis and Concomitant Eosinophilic Esophagitis: A Case Series. Can J Gastroenterol Hepatol. 2016; 2016:1761874. PMID: 27648438.
      View in: PubMed
    4. Ho TC, Zhang S, Sacchet MD, Weng H, Connolly CG, Henje Blom E, Han LK, Mobayed NO, Yang TT. Fusiform Gyrus Dysfunction is Associated with Perceptual Processing Efficiency to Emotional Faces in Adolescent Depression: A Model-Based Approach. Front Psychol. 2016; 7:40. PMID: 26869950.
      View in: PubMed
    5. Yamagata B, Murayama K, Black JM, Hancock R, Mimura M, Yang T, Reiss AL, Hoeft F. Female-Specific Intergenerational Transmission Patterns of the Human Corticolimbic Circuitry. J Neurosci. 2016 Jan 27; 36(4):1254-60. PMID: 26818513.
      View in: PubMed
    6. Henje-Blom E, Ho TC, Connolly CG, LeWinn KZ, Sacchet MD, Tymofiyeva O, Weng HY, Yang T. The neuroscience and context of adolescent depression. Acta Paediatr. 2016 Apr; 105(4):358-65. PMID: 26663379.
      View in: PubMed
    7. Max JE, Lopez A, Wilde EA, Bigler ED, Schachar RJ, Saunders A, Ewing-Cobbs L, Chapman SB, Yang TT, Levin HS. Anxiety disorders in children and adolescents in the second six months after traumatic brain injury. J Pediatr Rehabil Med. 2015 Dec 1; 8(4):345-55. PMID: 26684074.
      View in: PubMed
    8. Wagner A, Simmons AN, Oberndorfer TA, Frank GK, McCurdy-McKinnon D, Fudge JL, Yang TT, Paulus MP, Kaye WH. Altered sensitization patterns to sweet food stimuli in patients recovered from anorexia and bulimia nervosa. Psychiatry Res. 2015 Dec 30; 234(3):305-13. PMID: 26596520.
      View in: PubMed
    9. Max JE, Wilde EA, Bigler ED, Hanten G, Dennis M, Schachar RJ, Saunders AE, Ewing-Cobbs L, Chapman SB, Thompson WK, Yang TT, Levin HS. Personality Change Due to Traumatic Brain Injury in Children and Adolescents: Neurocognitive Correlates. J Neuropsychiatry Clin Neurosci. 2015; 27(4):272-9. PMID: 26185905; PMCID: PMC4618043.
    10. Bischoff-Grethe A, Buxton RB, Paulus MP, Fleisher AS, Yang TT, Brown GG. Striatal and Pallidal Activation during Reward Modulated Movement Using a Translational Paradigm. J Int Neuropsychol Soc. 2015 Jul; 21(6):399-411. PMID: 26156687; PMCID: PMC4668805 [Available on 01/09/16].
    11. Shott ME, Pryor TL, Yang TT, Frank GK. Greater Insula White Matter Fiber Connectivity in Women Recovered from Anorexia Nervosa. Neuropsychopharmacology. 2016 Jan; 41(2):498-507. PMID: 26076832.
      View in: PubMed
    12. Henje Blom E, Connolly CG, Ho TC, LeWinn KZ, Mobayed N, Han L, Paulus MP, Wu J, Simmons AN, Yang TT. Altered insular activation and increased insular functional connectivity during sad and happy face processing in adolescent major depressive disorder. J Affect Disord. 2015 Jun 1; 178:215-23. PMID: 25827506; PMCID: PMC4412607 [Available on 06/01/16].
    13. Wolkowitz OM, Mellon SH, Lindqvist D, Epel ES, Blackburn EH, Lin J, Reus VI, Burke H, Rosser R, Mahan L, Mackin S, Yang T, Weiner M, Mueller S. PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression. Psychiatry Res. 2015 Apr 30; 232(1):58-64. PMID: 25773002; PMCID: PMC4404215 [Available on 04/30/16].
    14. Max JE, Friedman K, Wilde EA, Bigler ED, Hanten G, Schachar RJ, Saunders AE, Dennis M, Ewing-Cobbs L, Chapman SB, Yang TT, Levin HS. Psychiatric disorders in children and adolescents 24 months after mild traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2015; 27(2):112-20. PMID: 25923850.
      View in: PubMed
    15. Wong JC, Dolan LM, Yang T, Hood KK. Insulin pump use and glycemic control in adolescents with type 1 diabetes: Predictors of change in method of insulin delivery across two years. Pediatr Diabetes. 2015 Dec; 16(8):592-9. PMID: 25387433; PMCID: PMC4458222.
    16. Ornstein TJ, Sagar S, Schachar RJ, Ewing-Cobbs L, Chapman SB, Dennis M, Saunders AE, Yang TT, Levin HS, Max JE. Neuropsychological performance of youth with secondary attention-deficit/hyperactivity disorder 6- and 12-months after traumatic brain injury. J Int Neuropsychol Soc. 2014 Nov; 20(10):971-81. PMID: 25489810.
      View in: PubMed
    17. Ho TC, Connolly CG, Henje Blom E, LeWinn KZ, Strigo IA, Paulus MP, Frank G, Max JE, Wu J, Chan M, Tapert SF, Simmons AN, Yang T. Emotion-Dependent Functional Connectivity of the Default Mode Network in Adolescent Depression. Biol Psychiatry. 2015 Nov 1; 78(9):635-46. PMID: 25483399; PMCID: PMC4362932 [Available on 11/01/16].
    18. Lindqvist D, Mueller S, Mellon SH, Su Y, Epel ES, Reus VI, Rosser R, Mahan L, Mackin RS, Yang TT, Wolkowitz OM. Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings. Psychiatry Res. 2014 Dec 30; 224(3):168-74. PMID: 25266915; PMCID: PMC4254356 [Available on 12/30/15].
    19. Henje Blom E, Duncan LG, Ho TC, Connolly CG, LeWinn KZ, Chesney M, Hecht FM, Yang TT. The development of an RDoC-based treatment program for adolescent depression: "Training for Awareness, Resilience, and Action" (TARA). Front Hum Neurosci. 2014; 8:630. PMID: 25191250; PMCID: PMC4137278.
    20. LeWinn KZ, Connolly CG, Wu J, Drahos M, Hoeft F, Ho TC, Simmons AN, Yang TT. White matter correlates of adolescent depression: structural evidence for frontolimbic disconnectivity. J Am Acad Child Adolesc Psychiatry. 2014 Aug; 53(8):899-909, 909.e1-7. PMID: 25062597; PMCID: PMC4112055.
    21. Blom EH, Forsman M, Yang TT, Serlachius E, Larsson JO. Latent Classes of Symptoms related to Clinically Depressed Mood in Adolescents. Scand J Child Adolesc Psychiatr Psychol. 2014; 2(1):19-28. PMID: 25419518.
      View in: PubMed
    22. Spadoni AD, Simmons AN, Yang TT, Tapert SF. Family history of alcohol use disorders and neuromaturation: a functional connectivity study with adolescents. Am J Drug Alcohol Abuse. 2013 Nov; 39(6):356-64. PMID: 24200205; PMCID: PMC3959877.
    23. Ho TC, Yang G, Wu J, Cassey P, Brown SD, Hoang N, Chan M, Connolly CG, Henje-Blom E, Duncan LG, Chesney MA, Paulus MP, Max JE, Patel R, Simmons AN, Yang TT. Functional connectivity of negative emotional processing in adolescent depression. J Affect Disord. 2014 Feb; 155:65-74. PMID: 24268546.
      View in: PubMed
    24. Oberndorfer TA, Frank GK, Simmons AN, Wagner A, McCurdy D, Fudge JL, Yang TT, Paulus MP, Kaye WH. Altered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa. Am J Psychiatry. 2013 Oct; 170(10):1143-51. PMID: 23732817; PMCID: PMC3971875.
    25. Oberndorfer T, Simmons A, McCurdy D, Strigo I, Matthews S, Yang T, Irvine Z, Kaye W. Greater anterior insula activation during anticipation of food images in women recovered from anorexia nervosa versus controls. Psychiatry Res. 2013 Nov 30; 214(2):132-41. PMID: 23993362; PMCID: PMC3880160.
    26. Frank GK, Shott ME, Hagman JO, Yang TT. Localized brain volume and white matter integrity alterations in adolescent anorexia nervosa. J Am Acad Child Adolesc Psychiatry. 2013 Oct; 52(10):1066-1075.e5. PMID: 24074473; PMCID: PMC4082770.
    27. Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT. Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents. Biol Psychiatry. 2013 Dec 15; 74(12):898-907. PMID: 23910949; PMCID: PMC4103629.
    28. Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT. Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression. J Am Acad Child Adolesc Psychiatry. 2013 Oct; 52(10):1076-1091.e2. PMID: 24074474; PMCID: PMC3825460.
    29. Wetherill RR, Squeglia LM, Yang TT, Tapert SF. A longitudinal examination of adolescent response inhibition: neural differences before and after the initiation of heavy drinking. Psychopharmacology (Berl). 2013 Dec; 230(4):663-71. PMID: 23832422; PMCID: PMC3840110.
    30. Mettler LN, Shott ME, Pryor T, Yang TT, Frank GK. White matter integrity is reduced in bulimia nervosa. Int J Eat Disord. 2013 Apr; 46(3):264-73. PMID: 23354827; PMCID: PMC3722416.
    31. Max JE, Pardo D, Hanten G, Schachar RJ, Saunders AE, Ewing-Cobbs L, Chapman SB, Dennis M, Wilde EA, Bigler ED, Thompson WK, Yang TT, Levin HS. Psychiatric disorders in children and adolescents six-to-twelve months after mild traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2013; 25(4):272-82. PMID: 24247854.
      View in: PubMed
    32. Max JE, Wilde EA, Bigler ED, Thompson WK, MacLeod M, Vasquez AC, Merkley TL, Hunter JV, Chu ZD, Yallampalli R, Hotz G, Chapman SB, Yang TT, Levin HS. Neuroimaging correlates of novel psychiatric disorders after pediatric traumatic brain injury. J Am Acad Child Adolesc Psychiatry. 2012 Nov; 51(11):1208-17. PMID: 23101746; PMCID: PMC3511860.
    33. Frank GK, Reynolds JR, Shott ME, Jappe L, Yang TT, Tregellas JR, O'Reilly RC. Anorexia nervosa and obesity are associated with opposite brain reward response. Neuropsychopharmacology. 2012 Aug; 37(9):2031-46. PMID: 22549118; PMCID: PMC3398719.
    34. Perlman G, Simmons AN, Wu J, Hahn KS, Tapert SF, Max JE, Paulus MP, Brown GG, Frank GK, Campbell-Sills L, Yang TT. Amygdala response and functional connectivity during emotion regulation: a study of 14 depressed adolescents. J Affect Disord. 2012 Jun; 139(1):75-84. PMID: 22401827; PMCID: PMC3340443.
    35. Max JE, Wilde EA, Bigler ED, MacLeod M, Vasquez AC, Schmidt AT, Chapman SB, Hotz G, Yang TT, Levin HS. Psychiatric disorders after pediatric traumatic brain injury: a prospective, longitudinal, controlled study. J Neuropsychiatry Clin Neurosci. 2012; 24(4):427-36. PMID: 23224448.
      View in: PubMed
    36. Max JE, Keatley E, Wilde EA, Bigler ED, Schachar RJ, Saunders AE, Ewing-Cobbs L, Chapman SB, Dennis M, Yang TT, Levin HS. Depression in children and adolescents in the first 6 months after traumatic brain injury. Int J Dev Neurosci. 2012 May; 30(3):239-45. PMID: 22197971; PMCID: PMC3322312.
    37. Wetherill RR, Bava S, Thompson WK, Boucquey V, Pulido C, Yang TT, Tapert SF. Frontoparietal connectivity in substance-naïve youth with and without a family history of alcoholism. Brain Res. 2012 Jan 13; 1432:66-73. PMID: 22138427; PMCID: PMC3246051.
    38. Jappe LM, Frank GK, Shott ME, Rollin MD, Pryor T, Hagman JO, Yang TT, Davis E. Heightened sensitivity to reward and punishment in anorexia nervosa. Int J Eat Disord. 2011 May; 44(4):317-24. PMID: 21472750; PMCID: PMC3072848.
    39. Kazlouski D, Rollin MD, Tregellas J, Shott ME, Jappe LM, Hagman JO, Pryor T, Yang TT, Frank GK. Altered fimbria-fornix white matter integrity in anorexia nervosa predicts harm avoidance. Psychiatry Res. 2011 May 31; 192(2):109-16. PMID: 21498054; PMCID: PMC3085716.
    40. Max JE, Keatley E, Wilde EA, Bigler ED, Levin HS, Schachar RJ, Saunders A, Ewing-Cobbs L, Chapman SB, Dennis M, Yang TT. Anxiety disorders in children and adolescents in the first six months after traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2011; 23(1):29-39. PMID: 21304136.
      View in: PubMed
    41. Yang TT, Simmons AN, Matthews SC, Tapert SF, Frank GK, Max JE, Bischoff-Grethe A, Lansing AE, Brown G, Strigo IA, Wu J, Paulus MP. Adolescents with major depression demonstrate increased amygdala activation. J Am Acad Child Adolesc Psychiatry. 2010 Jan; 49(1):42-51. PMID: 20215925; PMCID: PMC2935523.
    42. Bava S, Jacobus J, Mahmood O, Yang TT, Tapert SF. Neurocognitive correlates of white matter quality in adolescent substance users. Brain Cogn. 2010 Apr; 72(3):347-54. PMID: 19932550; PMCID: PMC2832074.
    43. Medina KL, McQueeny T, Nagel BJ, Hanson KL, Yang TT, Tapert SF. Prefrontal cortex morphometry in abstinent adolescent marijuana users: subtle gender effects. Addict Biol. 2009 Sep; 14(4):457-68. PMID: 19650817; PMCID: PMC2741544.
    44. Yang TT, Simmons AN, Matthews SC, Tapert SF, Frank GK, Bischoff-Grethe A, Lansing AE, Wu J, Brown GG, Paulus MP. Depressed adolescents demonstrate greater subgenual anterior cingulate activity. Neuroreport. 2009 Mar 4; 20(4):440-4. PMID: 19218875; PMCID: PMC2672880.
    45. Matthews S, Simmons A, Strigo I, Gianaros P, Yang T, Paulus M. Inhibition-related activity in subgenual cingulate is associated with symptom severity in major depression. Psychiatry Res. 2009 Apr 30; 172(1):1-6. PMID: 19239982.
      View in: PubMed
    46. Yang TT, Simmons AN, Matthews SC, Tapert SF, Frank GK, Bischoff-Grethe A, Lansing AE, Wu J, Paulus MP. Adolescent subgenual anterior cingulate activity is related to harm avoidance. Neuroreport. 2009 Jan 7; 20(1):19-23. PMID: 19034055; PMCID: PMC2852645.
    47. Matthews SC, Strigo IA, Simmons AN, Yang TT, Paulus MP. Decreased functional coupling of the amygdala and supragenual cingulate is related to increased depression in unmedicated individuals with current major depressive disorder. J Affect Disord. 2008 Nov; 111(1):13-20. PMID: 18603301.
      View in: PubMed
    48. Yang TT, Simmons AN, Matthews SC, Tapert SF, Bischoff-Grethe A, Frank GK, Arce E, Paulus MP. Increased amygdala activation is related to heart rate during emotion processing in adolescent subjects. Neurosci Lett. 2007 Nov 27; 428(2-3):109-14. PMID: 18029095; PMCID: PMC2171034.
    49. Frank GK, Oberndorfer TA, Simmons AN, Paulus MP, Fudge JL, Yang TT, Kaye WH. Sucrose activates human taste pathways differently from artificial sweetener. Neuroimage. 2008 Feb 15; 39(4):1559-69. PMID: 18096409.
      View in: PubMed
    50. Tapert SF, Schweinsburg AD, Drummond SP, Paulus MP, Brown SA, Yang TT, Frank LR. Functional MRI of inhibitory processing in abstinent adolescent marijuana users. Psychopharmacology (Berl). 2007 Oct; 194(2):173-83. PMID: 17558500; PMCID: PMC2269705.
    51. Yang TT, Menon V, Reid AJ, Gotlib IH, Reiss AL. Amygdalar activation associated with happy facial expressions in adolescents: a 3-T functional MRI study. J Am Acad Child Adolesc Psychiatry. 2003 Aug; 42(8):979-85. PMID: 12874501.
      View in: PubMed
    52. Yang TT, Menon V, Eliez S, Blasey C, White CD, Reid AJ, Gotlib IH, Reiss AL. Amygdalar activation associated with positive and negative facial expressions. Neuroreport. 2002 Oct 7; 13(14):1737-41. PMID: 12395114.
      View in: PubMed
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